Location: New York, NY
CIK: 0001263508 · Show all filings
Period: Q2 2017 (← Previous) (Next →)
Filing Date: Aug 14, 2017
Total Value: $11.44B (99.0% shares, 1.0% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| INCY | Incyte Corporation | 34,130,161 | $4.297B | 37.6% | $73.07 | +74.1% | COM | 45337C102 |
| — | Seattle Genetics, Inc. | 45,725,556 | $2.366B | 20.7% | $35.70 | — | COM | 812578102 |
| — | Alexion Pharmaceuticals, Inc. | 8,553,864 | $1.041B | 9.1% | $166.88 | — | COM | 015351109 |
| ACAD | ACADIA Pharmaceuticals Inc. | 25,819,768 | $720M | 6.3% | $16.42 | +81.5% | COM | 004225108 |
| BMRN | BioMarin Pharmaceutical Inc. | 5,905,673 | $536M | 4.7% | $79.34 | +14.7% | COM | 09061G101 |
| — | Genomic Health, Inc. | 13,779,866 | $449M | 3.9% | $31.71 | — | COM | 37244C101 |
| — | DBV Technologies S.A. | 5,509,560 | $197M | 1.7% | $32.87 | — | SPONSORED ADR | 23306J101 |
| ONC | BeiGene, Ltd. | 3,673,175 | $165M | 1.4% | $29.81 | — | SPONSORED ADR | 07725L102 |
| — | Aquinox Pharmaceuticals, Inc. | 10,934,154 | $154M | 1.3% | $13.36 | — | COM | 03842B101 |
| — | Achaogen, Inc. | 4,804,604 | $104M | 0.9% | $13.47 | — | COM | 004449104 |
| — | Amarin Corporation plc | 22,669,509 | $91.36M | 0.8% | $3.15 | — | SPONSORED ADR NEW | 023111206 |
| — | Advanced Accelerator Applications S.A. | 2,221,706 | $86.73M | 0.8% | $29.75 | — | SPONSORED ADS | 00790T100 |
| — | Spark Therapeutics, Inc. | 1,318,341 | $78.76M | 0.7% | $76.38 | — | COM | 84652J103 |
| — | Invitae Corporation | 7,288,300 | $69.68M | 0.6% | $15.87 | — | COM | 46185L103 |
| BCRX | BioCryst Pharmaceuticals, Inc. | 11,716,784 | $65.14M | 0.6% | $7.34 | -17.0% | COM | 09058V103 |
| — | Bellicum Pharmaceuticals, Inc. | 5,032,313 | $58.78M | 0.5% | $22.31 | — | COM | 079481107 |
| — | AveXis, Inc. | 625,000 | $51.35M | 0.4% | $62.98 | — | COM | 05366U100 |
| EXEL | Exelixis, Inc. | 2,082,012 | $51.28M | 0.4% | $7.37 | +187.1% | COM | 30161Q104 |
| ASND | Ascendis Pharma A/S | 1,751,463 | $48.62M | 0.4% | $21.73 | — | SPONSORED ADR | 04351P101 |
| — | Novavax, Inc. | 108,500,000 | $46.43M | 0.4% | $0.45 | — | NOTE 3.75% 2/1/2023 | 670002AB0 |
| HRTX | Heron Therapeutics, Inc. | 2,783,569 | $38.55M | 0.3% | $13.67 | +5.9% | COM | 427746102 |
| SGMO | Sangamo Therapeutics, Inc. | 4,113,376 | $36.2M | 0.3% | $11.28 | -43.1% | COM | 800677106 |
| — | bluebird bio, Inc. | 301,441 | $31.67M | 0.3% | $41.25 | — | COM | 09609G100 |
| — | Acorda Therapeutics, Inc. | 35,083,000 | $29.98M | 0.3% | $0.99 | — | NOTE 1.75% 6/15/2021 | 00484MAA4 |
| — | Versartis, Inc. | 1,660,593 | $28.98M | 0.3% | $22.68 | — | COM | 92529L102 |
| NBIX | Neurocrine Biosciences, Inc. | 616,682 | $28.37M | 0.2% | $28.92 | +67.7% | COM | 64125C109 |
| CERS | Cerus Corporation | 10,241,943 | $25.71M | 0.2% | $4.68 | -31.7% | COM | 157085101 |
| — | ImmunoGen, Inc. | 3,015,353 | $21.44M | 0.2% | $11.68 | — | COM | 45253H101 |
| — | Progenics Pharmaceuticals, Inc. | 3,150,808 | $21.39M | 0.2% | $4.44 | — | COM | 743187106 |
| HALO | Halozyme Therapeutics, Inc. | 1,581,424 | $20.27M | 0.2% | $7.32 | +82.4% | COM | 40637H109 |
| GLPG | Galapagos NV | 259,894 | $19.89M | 0.2% | $51.50 | — | SPONSORED ADR | 36315X101 |
| XNCR | Xencor, Inc. | 872,072 | $18.41M | 0.2% | $11.07 | +102.6% | COM | 98401F105 |
| — | Merus N.V. | 1,160,014 | $18.39M | 0.2% | $8.27 | — | COM | N5749R100 |
| — | Idera Pharmaceuticals, Inc. | 10,294,970 | $17.71M | 0.2% | $2.56 | — | COM NEW | 45168K306 |
| — | NeuroDerm Ltd. | 571,667 | $17.09M | 0.1% | $18.48 | — | ORD SHS | M74231107 |
| NTLA | Intellia Therapeutics, Inc. | 1,062,120 | $16.99M | 0.1% | $26.61 | -47.5% | COM | 45826J105 |
| — | Sage Therapeutics, Inc. | 208,328 | $16.59M | 0.1% | $37.36 | — | COM | 78667J108 |
| — | Aerie Pharmaceuticals, Inc. | 299,356 | $15.73M | 0.1% | $17.96 | — | COM | 00771V108 |
| — | La Jolla Pharmaceutical Company | 504,732 | $15.03M | 0.1% | $29.30 | — | COM PAR $.0001 2 | 503459604 |
| CPRX | Catalyst Pharmaceuticals, Inc. | 5,102,153 | $14.08M | 0.1% | $2.61 | -20.1% | COM | 14888U101 |
| — | Aimmune Therapeutics, Inc. | 673,908 | $13.86M | 0.1% | $16.20 | — | COM | 00900T107 |
| — | BioMarin Pharmaceutical Inc. | 12,228,000 | $13.55M | 0.1% | $1.06 | — | NOTE 0.75% 10/15/2018 | 09061GAE1 |
| — | Array BioPharma Inc. | 1,585,913 | $13.27M | 0.1% | $6.65 | — | COM | 04269X105 |
| — | Aegerion Pharmaceuticals, Inc. | 14,517,000 | $11.55M | 0.1% | $0.75 | — | NOTE 2.0% 8/15/2019 | 00767EAB8 |
| — | Foamix Pharmaceuticals Ltd. | 2,466,702 | $11.45M | 0.1% | $7.55 | — | SHS | M46135105 |
| — | Loxo Oncology, Inc. | 138,312 | $11.09M | 0.1% | $17.33 | — | COM | 548862101 |
| — | Abeona Therapeutics Inc. | 1,684,364 | $10.78M | 0.1% | $4.92 | — | COM | 00289Y107 |
| — | Ignyta, Inc. | 896,000 | $9.274M | 0.1% | $9.04 | — | COM | 451731103 |
| — | Syros Pharmaceuticals, Inc. | 574,835 | $9.249M | 0.1% | $16.82 | — | COM | 87184Q107 |
| LGND | Ligand Pharmaceuticals Incorporated | 73,386 | $8.909M | 0.1% | $41.68 | +67.8% | COM NEW | 53220K504 |
| ALKS | Alkermes plc | 150,251 | $8.71M | 0.1% | $70.02 | -17.0% | SHS | G01767105 |
| — | Achillion Pharmaceuticals, Inc. | 1,856,637 | $8.522M | 0.1% | $8.21 | — | COM | 00448Q201 |
| — | Mirati Therapeutics, Inc. | 2,269,198 | $8.283M | 0.1% | $18.66 | — | COM | 60468T105 |
| — | Intra-Cellular Therapies, Inc. | 609,166 | $7.566M | 0.1% | $37.28 | — | COM | 46116X101 |
| — | CymaBay Therapeutics, Inc. | 1,291,775 | $7.441M | 0.1% | $3.74 | — | COM | 23257D103 |
| — | Rigel Pharmaceuticals, Inc. | 2,518,882 | $6.877M | 0.1% | $2.56 | — | COM NEW | 766559603 |
| INSM | Insmed Incorporated | 400,000 | $6.864M | 0.1% | $14.37 | +18.8% | COM PAR $.01 | 457669307 |
| AGIO | Agios Pharmaceuticals, Inc. | 128,666 | $6.62M | 0.1% | $37.79 | +35.3% | COM | 00847X104 |
| MGNX | MacroGenics, Inc. | 363,676 | $6.368M | 0.1% | $23.98 | -20.4% | COM | 556099109 |
| — | GlycoMimetics, Inc. | 563,312 | $6.287M | 0.1% | $8.53 | — | COM | 38000Q102 |
| — | ContraFect Corporation | 4,045,876 | $5.867M | 0.1% | $2.48 | — | COM | 212326102 |
| — | Stemline Therapeutics, Inc. | 633,497 | $5.828M | 0.1% | $16.60 | — | COM | 85858C107 |
| — | Selecta Biosciences, Inc. | 289,809 | $5.756M | 0.1% | $16.30 | — | COM | 816212104 |
| — | Assembly Biosciences, Inc. | 250,000 | $5.163M | 0.0% | $13.24 | — | COM | 045396108 |
| — | Spring Bank Pharmaceuticals, Inc. | 373,144 | $5.052M | 0.0% | $10.28 | — | COM | 849431101 |
| — | Aeglea BioTherapeutics, Inc. | 1,137,872 | $4.381M | 0.0% | $4.02 | — | COM | 00773J103 |
| — | Albireo Pharma, Inc. | 200,000 | $4.12M | 0.0% | $20.60 | — | COM | 01345P106 |
| — | Array BioPharma Inc. | 3,000,000 | $4.066M | 0.0% | $1.25 | — | NOTE 3.0% 6/1/2020 | 04269XAA3 |
| — | NewLink Genetics Corporation | 500,000 | $3.675M | 0.0% | $7.35 | — | COM | 651511107 |
| — | Nabriva Therapeutics plc | 350,000 | $3.668M | 0.0% | $10.48 | — | SHS ADDED | G63637105 |
| — | Epizyme, Inc. | 232,481 | $3.51M | 0.0% | $21.12 | — | COM | 29428V104 |
| OVID | Ovid Therapeutics Inc. | 333,333 | $3.497M | 0.0% | $13.06 | 0.0% | COM ADDED | 690469101 |
| — | Ra Pharmaceuticals, Inc. | 177,952 | $3.335M | 0.0% | $15.19 | — | COM | 74933V108 |
| — | Adamas Pharmaceuticals, Inc. | 172,630 | $3.019M | 0.0% | $14.46 | — | COM | 00548A106 |
| — | Inotek Pharmaceuticals Corporation | 5,000,000 | $2.978M | 0.0% | $1.34 | — | NOTE 5.75% 8/1/2021 | 45780VAB8 |
| ANAB | AnaptysBio, Inc. | 117,211 | $2.805M | 0.0% | $23.32 | +7.8% | COM | 032724106 |
| — | Zogenix, Inc. | 185,290 | $2.687M | 0.0% | $13.50 | — | COM NEW | 98978L204 |
| — | Protalix BioTherapeutics, Inc. | 3,423,000 | $2.572M | 0.0% | $0.76 | — | NOTE 4.5% 9/15/2018 | 74365AAB7 |
| — | Alder BioPharmaceuticals, Inc. | 217,328 | $2.488M | 0.0% | $24.97 | — | COM | 014339105 |
| NTRA | Natera, Inc. | 228,676 | $2.483M | 0.0% | $13.15 | -25.7% | COM | 632307104 |
| — | Novavax, Inc. | 2,000,000 | $2.3M | 0.0% | $1.15 | — | COM | 670002104 |
| — | Akari Therapeutics plc | 496,901 | $2.291M | 0.0% | $21.86 | — | SPONSORED ADR | 00972G108 |
| — | Tonix Pharmaceuticals Holding Corp. | 510,922 | $2.212M | 0.0% | $4.63 | — | COM | 890260409 |
| — | Trevena, Inc. | 950,000 | $2.185M | 0.0% | $6.70 | — | COM | 89532E109 |
| — | Aevi Genomic Medicine, Inc. | 1,618,089 | $2.152M | 0.0% | $3.67 | — | COM | 00835P105 |
| ARGX | argenx SE | 100,000 | $2.121M | 0.0% | $21.21 | — | SPONSORED ADR ADDED | 04016X101 |
| — | Sunesis Pharmaceuticals, Inc. | 741,665 | $2.002M | 0.0% | $4.37 | — | COM PAR | 867328700 |
| — | Karyopharm Therapeutics Inc. | 216,990 | $1.964M | 0.0% | $31.09 | — | COM | 48576U106 |
| — | Trillium Therapeutics Inc. | 413,697 | $1.82M | 0.0% | $13.74 | — | COM NEW | 89620X506 |
| — | Dimension Therapeutics, Inc. | 1,251,881 | $1.815M | 0.0% | $11.23 | — | COM | 25433V105 |
| RARE | Ultragenyx Pharmaceutical Inc. | 25,000 | $1.553M | 0.0% | $51.09 | +17.9% | COM | 90400D108 |
| — | MediWound Ltd. | 226,000 | $1.537M | 0.0% | $11.38 | — | ORD SHS | M68830104 |
| — | Juno Therapeutics, Inc. | 50,000 | $1.495M | 0.0% | $52.22 | — | COM | 48205A109 |
| — | Immune Design Corp. | 148,937 | $1.452M | 0.0% | $20.65 | — | COM | 45252L103 |
| — | Seres Therapeutics, Inc. | 125,000 | $1.413M | 0.0% | $41.50 | — | COM | 81750R102 |
| — | Jounce Therapeutics, Inc. | 100,000 | $1.403M | 0.0% | $21.99 | — | COM | 481116101 |
| — | MyoKardia, Inc. | 100,000 | $1.31M | 0.0% | $16.34 | — | COM | 62857M105 |
| CLLS | Cellectis S.A. | 50,000 | $1.291M | 0.0% | $34.58 | — | SPONSORED ADS | 15117K103 |
| — | InVivo Therapeutics Holdings Corp. | 400,000 | $1.08M | 0.0% | $6.98 | — | COM NEW | 46186M209 |
| MDGL | Madrigal Pharmaceuticals, Inc. | 57,762 | $939K | 0.0% | $9.69 | +61.3% | COM | 558868105 |
| INFIQ | Infinity Pharmaceuticals, Inc. | 580,400 | $911K | 0.0% | $1.54 | +25.5% | COM | 45665G303 |
| — | Palatin Technologies, Inc. | 2,050,000 | $882K | 0.0% | $0.73 | — | COM PAR $.01 | 696077403 |
| — | Acceleron Pharma Inc. | 28,765 | $874K | 0.0% | $39.60 | — | COM | 00434H108 |
| — | Affimed N.V. | 400,000 | $820K | 0.0% | $6.30 | — | COM | N01045108 |
| — | Corbus Pharmaceuticals Holdings, Inc. | 130,129 | $820K | 0.0% | $8.45 | — | COM | 21833P103 |
| FLGT | Fulgent Genetics, Inc. | 125,000 | $799K | 0.0% | $9.20 | -12.4% | COM | 359664109 |
| — | Dynavax Technologies Corporation | 75,000 | $724K | 0.0% | $24.55 | — | COM NEW | 268158201 |
| ABUS | Arbutus Biopharma Corporation | 180,582 | $650K | 0.0% | $8.87 | -61.2% | COM | 03879J100 |
| — | Chimerix, Inc. | 115,216 | $628K | 0.0% | $40.26 | — | COM | 16934W106 |
| — | BioDelivery Sciences International, Inc. | 210,021 | $588K | 0.0% | $5.21 | — | COM | 09060J106 |
| — | Five Prime Therapeutics, Inc. | 19,247 | $580K | 0.0% | $16.80 | — | COM | 33830X104 |
| — | Bioverativ Inc. | 8,249 | $496K | 0.0% | $54.43 | — | COM | 09075E100 |
| — | ChemoCentryx, Inc. | 49,064 | $459K | 0.0% | $14.14 | — | COM | 16383L106 |
| — | Proteon Therapeutics, Inc. | 298,591 | $455K | 0.0% | $9.69 | — | COM | 74371L109 |
| ADAPY | Adaptimmune Therapeutics plc | 100,000 | $449K | 0.0% | $18.33 | — | SPONSORED ADR | 00653A107 |
| — | BioPharmX Corporation | 598,758 | $287K | 0.0% | $0.50 | — | COM | 09072X101 |
| — | Ritter Pharmaceuticals, Inc. | 400,000 | $220K | 0.0% | $4.45 | — | COM | 767836109 |
| — | Tenax Therapeutics, Inc. | 132,974 | $98,000 | 0.0% | $0.74 | — | COM | 88032L100 |
| — | Cyclacel Pharmaceuticals, Inc. | 13,253 | $82,000 | 0.0% | $7.20 | — | PFD CONV EX 6% | 23254L207 |
| — | BioTime, Inc. | 20,084 | $7,000 | 0.0% | $1.07 | — | *W EXP 10/1/201 | 09066L162 |