Location: Baltimore, MD
CIK: 0001595725 · Show all filings
Period: Q1 2021 (← Previous) (Next →)
Filing Date: May 17, 2021
Total Value: $4.584B (99.1% shares, 0.9% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| AGIO | AGIOS PHARMACEUTICALS INC | 2,543,600 | $131M | 2.9% | $42.75 | +15.9% | COM | 00847X104 |
| HUM | HUMANA INC | 301,000 | $126M | 2.8% | $338.61 | +12.6% | COM | 444859102 |
| ZLAB | ZAI LAB LTD | 933,500 | $125M | 2.7% | $49.06 | — | ADR | 98887Q104 |
| AVIR | ATEA PHARMACEUTICALS INC | 1,694,903 | $105M | 2.3% | $32.23 | +109.6% | COM | 04683R106 |
| UNH | UNITEDHEALTH GROUP INC | 275,000 | $102M | 2.2% | $189.39 | +68.8% | COM | 91324P102 |
| — | FIVE PRIME THERAPEUTICS INC | 2,660,822 | $100M | 2.2% | $31.99 | — | COM | 33830X104 |
| NBIX | NEUROCRINE BIOSCIENCES INC | 1,015,000 | $98.71M | 2.2% | $73.06 | +43.5% | COM | 64125C109 |
| IMCR | IMMUNOCORE HLDGS PLC | 2,292,285 | $97.58M | 2.1% | $42.57 | — | ADS | 45258D105 |
| PODD | INSULET CORP | 371,000 | $96.8M | 2.1% | $141.29 | +89.5% | COM | 45784P101 |
| ALGN | ALIGN TECHNOLOGY INC | 177,500 | $96.12M | 2.1% | $261.79 | +111.2% | COM | 016255101 |
| ACRS | ACLARIS THERAPEUTICS INC | 3,569,192 | $89.94M | 2.0% | $10.01 | +95.4% | COM | 00461U105 |
| ISRG | INTUITIVE SURGICAL INC | 120,000 | $88.67M | 1.9% | $105.96 | +137.4% | COM NEW | 46120E602 |
| IDXX | IDEXX LABS INC | 180,000 | $88.08M | 1.9% | $292.33 | +71.4% | COM | 45168D104 |
| HCA | HCA HEALTHCARE INC | 450,000 | $84.75M | 1.8% | $96.26 | +75.5% | COM | 40412C101 |
| — | INVITAE CORP | 2,213,977 | $84.6M | 1.8% | $23.00 | — | COM | 46185L103 |
| NVAX | NOVAVAX INC | 461,000 | $83.58M | 1.8% | $40.40 | +393.2% | COM NEW | 670002401 |
| ARGX | ARGENX SE | 300,000 | $82.62M | 1.8% | $127.14 | — | SPONSORED ADR | 04016X101 |
| FRPT | FRESHPET INC | 506,500 | $80.44M | 1.8% | $50.14 | +200.8% | COM | 358039105 |
| EXAS | EXACT SCIENCES CORP | 570,000 | $75.11M | 1.6% | $56.53 | +142.1% | COM | 30063P105 |
| — | BLUEPRINT MEDICINES CORP | 746,732 | $72.61M | 1.6% | $69.72 | — | COM | 09627Y109 |
| PCRX | PACIRA BIOSCIENCES INC | 1,025,000 | $71.84M | 1.6% | $48.35 | +47.7% | COM | 695127100 |
| ONC | BEIGENE LTD | 200,000 | $69.62M | 1.5% | $43.43 | — | SPONSORED ADR | 07725L102 |
| — | NEVRO CORP | 485,000 | $67.66M | 1.5% | $95.91 | — | COM | 64157F103 |
| IRTC | IRHYTHM TECHNOLOGIES INC | 432,496 | $60.06M | 1.3% | $54.86 | +226.7% | COM | 450056106 |
| — | HORIZON THERAPEUTICS PUB L | 625,000 | $57.52M | 1.3% | $77.68 | — | SHS | G46188101 |
| — | MIRATI THERAPEUTICS INC | 323,647 | $55.44M | 1.2% | $73.57 | — | COM | 60468T105 |
| TFX | TELEFLEX INCORPORATED | 130,000 | $54.01M | 1.2% | $242.14 | +60.1% | COM | 879369106 |
| — | BOLT BIOTHERAPEUTICS INC | 1,559,248 | $51.31M | 1.1% | $32.91 | — | COM | 097702104 |
| RARE | ULTRAGENYX PHARMACEUTICAL IN | 450,000 | $51.24M | 1.1% | $55.19 | +146.7% | COM | 90400D108 |
| EW | EDWARDS LIFESCIENCES CORP | 582,000 | $48.68M | 1.1% | $59.31 | +42.5% | COM | 28176E108 |
| — | MERSANA THERAPEUTICS INC | 2,775,127 | $44.9M | 1.0% | $16.44 | — | COM | 59045L106 |
| CGEM | CULLINAN ONCOLOGY INC | 1,075,912 | $44.83M | 1.0% | $40.60 | 0.0% | COM | 230031106 |
| — | KARUNA THERAPEUTICS INC | 368,764 | $44.34M | 1.0% | $66.05 | — | COM | 48576A100 |
| PHR | PHREESIA INC | 850,000 | $44.28M | 1.0% | $28.21 | +123.3% | COM | 71944F106 |
| — | EARGO INC | 851,671 | $42.54M | 0.9% | $44.82 | — | COM | 270087109 |
| ALNY | ALNYLAM PHARMACEUTICALS INC | 300,000 | $42.36M | 0.9% | $85.91 | +75.2% | COM | 02043Q107 |
| — | COVETRUS INC | 1,400,000 | $41.96M | 0.9% | $21.36 | — | COM | 22304C100 |
| ARVN | ARVINAS INC | 621,800 | $41.1M | 0.9% | $32.84 | +133.0% | COM | 04335A105 |
| EHC | ENCOMPASS HEALTH CORP | 500,000 | $40.95M | 0.9% | $45.98 | +34.4% | COM | 29261A100 |
| ACHC | ACADIA HEALTHCARE COMPANY IN | 700,000 | $40M | 0.9% | $44.80 | +20.8% | COM | 00404A109 |
| PEN | PENUMBRA INC | 147,500 | $39.91M | 0.9% | $55.16 | +368.0% | COM | 70975L107 |
| TVTX | TRAVERE THERAPEUTICS INC | 1,475,564 | $36.84M | 0.8% | $24.67 | +12.0% | COM | 89422G107 |
| HCAT | HEALTH CATALYST INC | 785,000 | $36.71M | 0.8% | $33.94 | +42.7% | COM | 42225T107 |
| — | ALLAKOS INC | 305,706 | $35.09M | 0.8% | $73.38 | — | COM | 01671P100 |
| — | SEAGEN INC | 250,000 | $34.72M | 0.8% | $175.14 | — | COM | 81181C104 |
| ARDX | ARDELYX INC | 5,176,561 | $34.27M | 0.7% | $7.05 | -2.7% | COM | 039697107 |
| AZN | ASTRAZENECA PLC | 650,000 | $32.32M | 0.7% | $49.72 | — | SPONSORED ADR | 046353108 |
| BIIB | BIOGEN INC | 113,500 | $31.75M | 0.7% | $299.45 | -9.9% | COM | 09062X103 |
| BSX | BOSTON SCIENTIFIC CORP | 800,000 | $30.92M | 0.7% | $35.85 | +5.6% | COM | 101137107 |
| GH | GUARDANT HEALTH INC | 200,000 | $30.53M | 0.7% | $42.73 | +253.7% | COM | 40131M109 |
| MDGL | MADRIGAL PHARMACEUTICALS INC | 258,500 | $30.24M | 0.7% | $40.26 | +189.6% | COM | 558868105 |
| ASND | ASCENDIS PHARMA A/S | 233,500 | $30.09M | 0.7% | $29.70 | — | SPONSORED ADR | 04351P101 |
| MIRM | MIRUM PHARMACEUTICALS INC | 1,502,800 | $29.79M | 0.6% | $12.84 | +49.1% | COM | 604749101 |
| EVH | EVOLENT HEALTH INC | 1,445,000 | $29.19M | 0.6% | $19.02 | 0.0% | CL A | 30050B101 |
| PRTA | PROTHENA CORP PLC | 1,156,900 | $29.06M | 0.6% | $11.75 | +60.1% | SHS | G72800108 |
| — | SHOCKWAVE MED INC | 220,000 | $28.66M | 0.6% | $50.28 | — | COM | 82489T104 |
| — | ACCOLADE INC | 625,000 | $28.36M | 0.6% | $41.47 | — | COM | 00437E102 |
| ACAD | ACADIA PHARMACEUTICALS INC | 1,076,200 | $27.77M | 0.6% | $41.60 | +5.8% | COM | 004225108 |
| LUNG | PULMONX CORP | 592,500 | $27.1M | 0.6% | $50.28 | +14.1% | COM | 745848101 |
| — | SPRUCE BIOSCIENCES INC | 1,579,301 | $26.22M | 0.6% | $24.31 | — | COM | 85209E109 |
| ADPT | ADAPTIVE BIOTECHNOLOGIES COR | 650,000 | $26.17M | 0.6% | $43.96 | +23.1% | COM | 00650F109 |
| — | AMARIN CORP PLC | 4,195,000 | $26.05M | 0.6% | $4.95 | — | SPONS ADR NEW | 023111206 |
| — | PPD INC | 675,000 | $25.54M | 0.6% | $23.83 | — | COM | 69355F102 |
| SRPT | SAREPTA THERAPEUTICS INC | 328,750 | $24.5M | 0.5% | $54.43 | +69.5% | COM | 803607100 |
| — | EPIZYME INC | 2,802,954 | $24.41M | 0.5% | $13.98 | — | COM | 29428V104 |
| KYMR | KYMERA THERAPEUTICS INC | 621,777 | $24.16M | 0.5% | $30.53 | +97.2% | COM | 501575104 |
| NVCR | NOVOCURE LTD | 175,000 | $23.13M | 0.5% | $37.58 | +320.9% | ORD SHS | G6674U108 |
| — | INTERSECT ENT INC | 1,080,200 | $22.55M | 0.5% | $23.15 | — | COM | 46071F103 |
| COLL | COLLEGIUM PHARMACEUTICAL INC | 920,000 | $21.8M | 0.5% | $15.97 | +48.7% | COM | 19459J104 |
| INSP | INSPIRE MED SYS INC | 100,000 | $20.7M | 0.5% | $74.71 | +184.5% | COM | 457730109 |
| — | ABCAM PLC | 1,069,236 | $20.55M | 0.4% | $21.24 | — | ADS | 000380204 |
| — | OAK STR HEALTH INC | 375,000 | $20.35M | 0.4% | $54.98 | — | COM | 67181A107 |
| KURA | KURA ONCOLOGY INC | 710,035 | $20.07M | 0.4% | $34.14 | -7.3% | COM | 50127T109 |
| BMRN | BIOMARIN PHARMACEUTICAL INC | 253,500 | $19.14M | 0.4% | $85.83 | -4.8% | COM | 09061G101 |
| — | CYTOKINETICS INC | 8,000,000 | $19.09M | 0.4% | $1.32 | — | NOTE 4.000%11/1 | 23282WAA8 |
| RCKT | ROCKET PHARMACEUTICALS INC | 403,070 | $17.88M | 0.4% | $36.45 | +50.6% | COM | 77313F106 |
| — | SIERRA ONCOLOGY INC | 1,017,358 | $17.53M | 0.4% | $16.56 | — | COM NEW | 82640U404 |
| — | GAMIDA CELL LTD | 2,100,300 | $16.99M | 0.4% | $4.95 | — | SHS | M47364100 |
| — | INOZYME PHARMA INC | 827,900 | $16.39M | 0.4% | $26.29 | — | COM | 45790W108 |
| PRLD | PRELUDE THERAPEUTICS INC | 378,195 | $16.39M | 0.4% | $30.04 | +120.9% | COM | 74065P101 |
| — | DYNAVAX TECHNOLOGIES CORP | 1,658,520 | $16.3M | 0.4% | $6.77 | — | COM NEW | 268158201 |
| — | RIGEL PHARMACEUTICALS INC | 4,742,000 | $16.22M | 0.4% | $2.87 | — | COM NEW | 766559603 |
| NKTX | NKARTA INC | 491,848 | $16.18M | 0.4% | $29.47 | +62.1% | COM | 65487U108 |
| MREO | MEREO BIOPHARMA GROUP PLC | 4,494,869 | $15.15M | 0.3% | $3.37 | — | ADS | 589492107 |
| — | AKERO THERAPEUTICS INC | 521,171 | $15.12M | 0.3% | $24.66 | — | COM | 00973Y108 |
| — | ESSA PHARMA INC | 503,035 | $14.61M | 0.3% | $29.05 | — | COM NEW | 29668H708 |
| — | ATHIRA PHARMA INC | 788,202 | $14.5M | 0.3% | $18.46 | — | COM | 04746L104 |
| — | OLINK HLDG AB | 400,000 | $14.4M | 0.3% | $36.00 | — | SPONSORED ADS | 680710100 |
| SPRO | SPERO THERAPEUTICS INC | 965,928 | $14.22M | 0.3% | $11.82 | +48.9% | COM | 84833T103 |
| — | GOSSAMER BIO INC | 15,573,000 | $13.98M | 0.3% | $1.01 | — | NOTE 5.000% 6/0 | 38341PAA0 |
| TBPH | THERAVANCE BIOPHARMA INC | 682,600 | $13.93M | 0.3% | $21.11 | -10.0% | COM | G8807B106 |
| — | CEREVEL THERAPEUTICS HLDNG I | 1,005,100 | $13.8M | 0.3% | $16.58 | — | COM | 15678U128 |
| — | APPLIED THERAPEUTICS INC | 701,680 | $13.16M | 0.3% | $31.74 | — | COM | 03828A101 |
| TGTX | TG THERAPEUTICS INC | 266,520 | $12.85M | 0.3% | $16.11 | +198.3% | COM | 88322Q108 |
| RYTM | RHYTHM PHARMACEUTICALS INC | 599,280 | $12.75M | 0.3% | $24.11 | +20.3% | COM | 76243J105 |
| GLPG | GALAPAGOS NV | 165,000 | $12.72M | 0.3% | $55.87 | — | SPON ADR | 36315X101 |
| MGNX | MACROGENICS INC | 393,479 | $12.53M | 0.3% | $22.34 | +8.7% | COM | 556099109 |
| — | AEGLEA BIOTHERAPEUTICS INC | 1,577,296 | $12.49M | 0.3% | $7.80 | — | COM | 00773J103 |
| INNV | INNOVAGE HLDG CORP | 475,000 | $12.25M | 0.3% | $24.64 | 0.0% | COM | 45784A104 |
| — | PARATEK PHARMACEUTICALS INC | 1,684,714 | $11.89M | 0.3% | $6.16 | — | COM | 699374302 |
| BAX | BAXTER INTL INC | 140,000 | $11.81M | 0.3% | $64.04 | +11.6% | COM | 071813109 |
| ANAB | ANAPTYSBIO INC | 535,232 | $11.53M | 0.3% | $28.24 | -10.6% | COM | 032724106 |
| STTK | SHATTUCK LABS INC | 388,499 | $11.36M | 0.2% | $32.14 | +30.7% | COM | 82024L103 |
| CNMD | CONMED CORP | 85,085 | $11.11M | 0.2% | $89.83 | +28.4% | COM | 207410101 |
| TARA | PROTARA THERAPEUTICS INC | 689,942 | $10.86M | 0.2% | $22.87 | -18.9% | COM STK | 74365U107 |
| — | FIBROGEN INC | 312,687 | $10.85M | 0.2% | $30.26 | — | COM | 31572Q808 |
| — | TRANSLATE BIO INC | 649,900 | $10.72M | 0.2% | $12.61 | — | COM | 89374L104 |
| — | NGM BIOPHARMACEUTICALS INC | 364,800 | $10.61M | 0.2% | $14.90 | — | COM | 62921N105 |
| — | PROMETHEUS BIOSCIENCES INC | 574,858 | $10.5M | 0.2% | $18.26 | — | COM | 74349U108 |
| CGEN | COMPUGEN LTD | 1,219,488 | $10.47M | 0.2% | $6.07 | +82.6% | ORD | M25722105 |
| — | CHINOOK THERAPEUTICS INC | 673,049 | $10.46M | 0.2% | $15.86 | — | COM | 16961L106 |
| XENE | XENON PHARMACEUTICALS INC | 572,500 | $10.25M | 0.2% | $14.47 | +17.1% | COM | 98420N105 |
| — | KINNATE BIOPHARMA INC | 326,386 | $10.17M | 0.2% | $39.78 | — | COM | 49705R105 |
| — | FUSION PHARMACEUTICALS INC | 948,327 | $10.17M | 0.2% | $17.41 | — | COM | 36118A100 |
| AUPH | AURINIA PHARMACEUTICALS INC | 781,569 | $10.15M | 0.2% | $14.49 | +0.2% | COM | 05156V102 |
| FOLD | AMICUS THERAPEUTICS INC | 1,012,506 | $10M | 0.2% | $11.49 | +34.7% | COM | 03152W109 |
| — | ORION ACQUISITION CORP | 1,000,000 | $10M | 0.2% | $10.00 | — | UNIT 02/19/2026 | 68626A207 |
| DSGN | DESIGN THERAPEUTICS INC | 327,250 | $9.785M | 0.2% | $31.14 | 0.0% | COM | 25056L103 |
| NRIX | NURIX THERAPEUTICS INC | 310,950 | $9.667M | 0.2% | $27.38 | +38.2% | COM | 67080M103 |
| LEGN | LEGEND BIOTECH CORP | 312,618 | $9.072M | 0.2% | $38.05 | — | SPONSORED ADS | 52490G102 |
| RLAY | RELAY THERAPEUTICS INC | 252,127 | $8.716M | 0.2% | $38.13 | +13.8% | COM | 75943R102 |
| ADAPY | ADAPTIMMUNE THERAPEUTICS PLC | 1,545,000 | $8.204M | 0.2% | $10.05 | — | SPONDS ADR | 00653A107 |
| WST | WEST PHARMACEUTICAL SVSC INC | 28,500 | $8.031M | 0.2% | $96.51 | +193.0% | COM | 955306105 |
| — | ATRECA INC | 453,930 | $6.959M | 0.2% | $13.97 | — | CL A COM | 04965G109 |
| — | CHIASMA INC | 2,174,583 | $6.806M | 0.1% | $7.90 | — | COM | 16706W102 |
| — | TRILLIUM THERAPEUTICS INC | 620,800 | $6.667M | 0.1% | $4.22 | — | COM NEW | 89620X506 |
| — | ACELRX PHARMACEUTICALS INC | 3,785,457 | $6.435M | 0.1% | $1.42 | — | COM | 00444T100 |
| FATE | FATE THERAPEUTICS INC | 70,000 | $5.772M | 0.1% | $95.82 | 0.0% | COM | 31189P102 |
| — | CONSTELLATION PHARMCETICLS I | 232,000 | $5.426M | 0.1% | $37.77 | — | COM | 210373106 |
| DXCM | DEXCOM INC | 15,000 | $5.391M | 0.1% | $93.87 | 0.0% | COM | 252131107 |
| — | PHASEBIO PHARMACEUTICALS INC | 1,553,974 | $5.377M | 0.1% | $5.65 | — | COM | 717224109 |
| GRTX | GALERA THERAPEUTICS INC | 568,252 | $5.012M | 0.1% | $12.01 | -8.6% | COM | 36338D108 |
| NUVB | NUVATION BIO INC | 402,088 | $4.202M | 0.1% | $11.18 | 0.0% | COM CL A | 67080N101 |
| RPRX | ROYALTY PHARMA PLC | 80,000 | $3.49M | 0.1% | $49.50 | -4.2% | SHS CLASS A | G7709Q104 |
| — | RETROPHIN INC | 3,250,000 | $3.36M | 0.1% | $0.79 | — | NOTE 2.500% 9/1 | 761299AB2 |
| — | BCLS ACQUISITION CORP | 309,000 | $3.266M | 0.1% | $11.14 | — | COM CL A | G0904B105 |
| — | POSEIDA THERAPEUTICS INC | 289,754 | $2.767M | 0.1% | $8.87 | — | COM | 73730P108 |
| — | CONNECT BIOPHARMA HLDGS LTD | 119,114 | $2.204M | 0.0% | $18.50 | — | ADS | 207523101 |
| — | LIFESCI ACQUISITION II CORP | 206,200 | $2.091M | 0.0% | $10.67 | — | COM | 53229E103 |
| — | FS DEVELOPMENT CORP II | 209,332 | $2.085M | 0.0% | $9.96 | — | COM CL A | 30318F100 |
| — | EUCRATES BIOMEDICAL ACQU COR | 206,000 | $2.063M | 0.0% | $10.66 | — | UNIT 10/23/2027 | G3141W114 |
| — | TURMERIC ACQUISITION CORP | 206,000 | $2.06M | 0.0% | $10.27 | — | UNIT 10/08/2025 | G9127T116 |
| — | JIYA ACQUISITION CORP | 206,200 | $2.029M | 0.0% | $10.30 | — | COM CL A | 47760M102 |
| — | POPULATION HEALTH INVS CO IN | 201,044 | $2.02M | 0.0% | $10.45 | — | UNIT 99/99/9999 | G71716123 |
| MLTX | HELIX ACQUISITION CORP | 154,500 | $1.576M | 0.0% | $11.37 | — | COM CL A | G4444C102 |
| — | THERAVANCE BIOPHARMA INC | 1,500,000 | $1.526M | 0.0% | $1.14 | — | NOTE 3.250%11/0 | 88339KAA0 |
| — | RADIUS HEALTH INC | 1,500,000 | $1.401M | 0.0% | $1.01 | — | NOTE 3.000% 9/0 | 750469AA6 |
| — | NEUROCRINE BIOSCIENCES INC | 1,000,000 | $1.354M | 0.0% | $1.45 | — | NOTE 2.250% 5/1 | 64125CAD1 |
| — | PACIRA BIOSCIENCES INC | 1,000,000 | $1.211M | 0.0% | $0.91 | — | NOTE 2.375% 4/0 | 695127AD2 |
| — | NEVRO CORP | 500,000 | $771K | 0.0% | $1.37 | — | NOTE 2.750% 4/0 | 64157FAC7 |
| — | NUVATION BIO INC | 134,028 | $358K | 0.0% | $2.67 | — | *W EXP 07/07/202 | 67080N119 |