Location: Baltimore, MD
CIK: 0001595725 · Show all filings
Period: Q4 2020 (← Previous) (Next →)
Filing Date: Feb 16, 2021
Total Value: $4.716B (99.0% shares, 1.0% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| NBIX | NEUROCRINE BIOSCIENCES INC | 1,575,000 | $151M | 3.2% | $73.06 | +32.2% | COM | 64125C109 |
| IRTC | IRHYTHM TECHNOLOGIES INC | 625,000 | $148M | 3.1% | $54.86 | +315.4% | COM | 450056106 |
| UNH | UNITEDHEALTH GROUP INC | 405,000 | $142M | 3.0% | $189.39 | +62.7% | COM | 91324P102 |
| HUM | HUMANA INC | 285,000 | $117M | 2.5% | $336.21 | +18.0% | COM | 444859102 |
| ZLAB | ZAI LAB LTD | 854,899 | $116M | 2.5% | $41.30 | — | ADR | 98887Q104 |
| AGIO | AGIOS PHARMACEUTICALS INC | 2,523,521 | $109M | 2.3% | $42.75 | -7.5% | COM | 00847X104 |
| ISRG | INTUITIVE SURGICAL INC | 120,000 | $98.17M | 2.1% | $105.96 | +134.3% | COM NEW | 46120E602 |
| — | BLUEPRINT MEDICINES CORP | 842,000 | $94.43M | 2.0% | $69.72 | — | COM | 09627Y109 |
| ALGN | ALIGN TECHNOLOGY INC | 163,500 | $87.37M | 1.9% | $236.88 | +89.8% | COM | 016255101 |
| ACAD | ACADIA PHARMACEUTICALS INC | 1,612,500 | $86.2M | 1.8% | $41.60 | +19.3% | COM | 004225108 |
| ARGX | ARGENX SE | 287,500 | $84.55M | 1.8% | $120.69 | — | SPONSORED ADR | 04016X101 |
| — | MIRATI THERAPEUTICS INC | 373,152 | $81.96M | 1.7% | $73.57 | — | COM | 60468T105 |
| PODD | INSULET CORP | 318,000 | $81.29M | 1.7% | $120.20 | +106.4% | COM | 45784P101 |
| RARE | ULTRAGENYX PHARMACEUTICAL IN | 566,500 | $78.42M | 1.7% | $55.19 | +114.9% | COM | 90400D108 |
| — | INVITAE CORP | 1,852,067 | $77.44M | 1.6% | $20.03 | — | COM | 46185L103 |
| HCA | HCA HEALTHCARE INC | 450,000 | $74.01M | 1.6% | $96.26 | +45.2% | COM | 40412C101 |
| FRPT | FRESHPET INC | 506,500 | $71.92M | 1.5% | $50.14 | +157.4% | COM | 358039105 |
| AVIR | ATEA PHARMACEUTICALS INC | 1,697,403 | $70.92M | 1.5% | $32.23 | 0.0% | COM | 04683R106 |
| — | NEVRO CORP | 395,000 | $68.38M | 1.4% | $85.97 | — | COM | 64157F103 |
| EXAS | EXACT SCIENCES CORP | 485,000 | $64.26M | 1.4% | $42.45 | +184.9% | COM | 30063P105 |
| ARVN | ARVINAS INC | 746,000 | $63.36M | 1.3% | $32.84 | +5.0% | COM | 04335A105 |
| NVAX | NOVAVAX INC | 563,205 | $62.8M | 1.3% | $40.40 | +163.1% | COM NEW | 670002401 |
| IDXX | IDEXX LABS INC | 125,000 | $62.48M | 1.3% | $200.51 | +123.1% | COM | 45168D104 |
| PCRX | PACIRA BIOSCIENCES INC | 1,025,000 | $61.34M | 1.3% | $48.35 | +21.1% | COM | 695127100 |
| ONC | BEIGENE LTD | 225,000 | $58.14M | 1.2% | $43.43 | — | SPONSORED ADR | 07725L102 |
| SRPT | SAREPTA THERAPEUTICS INC | 328,750 | $56.05M | 1.2% | $54.43 | +172.2% | COM | 803607100 |
| — | MERSANA THERAPEUTICS INC | 2,063,667 | $54.91M | 1.2% | $16.53 | — | COM | 59045L106 |
| TFX | TELEFLEX INCORPORATED | 130,000 | $53.5M | 1.1% | $242.14 | +47.5% | COM | 879369106 |
| EW | EDWARDS LIFESCIENCES CORP | 582,000 | $53.1M | 1.1% | $59.31 | +39.8% | COM | 28176E108 |
| — | ALEXION PHARMACEUTICALS INC | 306,750 | $47.93M | 1.0% | $124.26 | — | COM | 015351109 |
| — | ALLAKOS INC | 341,500 | $47.81M | 1.0% | $73.38 | — | COM | 01671P100 |
| PHR | PHREESIA INC | 850,000 | $46.12M | 1.0% | $28.21 | +52.1% | COM | 71944F106 |
| — | HORIZON THERAPEUTICS PUB L | 625,000 | $45.72M | 1.0% | $77.68 | — | SHS | G46188101 |
| KYMR | KYMERA THERAPEUTICS INC | 713,865 | $44.26M | 0.9% | $30.53 | +59.8% | COM | 501575104 |
| CNC | CENTENE CORP DEL | 730,000 | $43.82M | 0.9% | $60.49 | +5.0% | COM | 15135B101 |
| — | SEAGEN INC | 250,000 | $43.78M | 0.9% | $175.14 | — | COM | 81181C104 |
| ALNY | ALNYLAM PHARMACEUTICALS INC | 335,000 | $43.54M | 0.9% | $85.91 | +55.4% | COM | 02043Q107 |
| EHC | ENCOMPASS HEALTH CORP | 500,000 | $41.34M | 0.9% | $45.98 | +20.9% | COM | 29261A100 |
| IMVT | IMMUNOVANT INC | 891,000 | $41.16M | 0.9% | $26.59 | +73.9% | COM | 45258J102 |
| — | EARGO INC | 900,000 | $40.34M | 0.9% | $44.82 | — | COM | 270087109 |
| INSP | INSPIRE MED SYS INC | 213,350 | $40.13M | 0.9% | $74.71 | +118.9% | COM | 457730109 |
| — | SPRUCE BIOSCIENCES INC | 1,631,000 | $39.65M | 0.8% | $24.31 | — | COM | 85209E109 |
| ASND | ASCENDIS PHARMA A/S | 233,500 | $38.94M | 0.8% | $29.70 | — | SPONSORED ADR | 04351P101 |
| ADPT | ADAPTIVE BIOTECHNOLOGIES COR | 635,000 | $37.55M | 0.8% | $43.72 | +18.0% | COM | 00650F109 |
| — | COVETRUS INC | 1,285,000 | $36.93M | 0.8% | $20.58 | — | COM | 22304C100 |
| ACHC | ACADIA HEALTHCARE COMPANY IN | 700,000 | $35.18M | 0.7% | $44.80 | -11.0% | COM | 00404A109 |
| LUNG | PULMONX CORP | 500,000 | $34.51M | 0.7% | $48.97 | 0.0% | COM | 745848101 |
| HCAT | HEALTH CATALYST INC | 785,000 | $34.17M | 0.7% | $33.94 | +8.7% | COM | 42225T107 |
| ARDX | ARDELYX INC | 5,148,112 | $33.31M | 0.7% | $7.05 | -15.8% | COM | 039697107 |
| NKTX | NKARTA INC | 541,000 | $33.26M | 0.7% | $29.47 | +40.9% | COM | 65487U108 |
| BIIB | BIOGEN INC | 130,000 | $31.83M | 0.7% | $303.47 | -14.6% | Call | 09062X103 |
| NVCR | NOVOCURE LTD | 175,000 | $30.28M | 0.6% | $37.58 | +264.1% | ORD SHS | G6674U108 |
| — | ATHIRA PHARMA INC | 860,902 | $29.49M | 0.6% | $18.46 | — | COM | 04746L104 |
| BSX | BOSTON SCIENTIFIC CORP | 800,000 | $28.76M | 0.6% | $35.85 | +0.5% | COM | 101137107 |
| BFAM | BRIGHT HORIZONS FAM SOL IN D | 165,500 | $28.63M | 0.6% | $118.86 | +37.7% | COM | 109194100 |
| MDGL | MADRIGAL PHARMACEUTICALS INC | 256,768 | $28.55M | 0.6% | $40.26 | +203.6% | COM | 558868105 |
| TVTX | TRAVERE THERAPEUTICS INC | 1,021,000 | $27.83M | 0.6% | $23.35 | 0.0% | COM | 89422G107 |
| PEN | PENUMBRA INC | 159,000 | $27.82M | 0.6% | $55.16 | +297.1% | COM | 70975L107 |
| — | EPIZYME INC | 2,553,208 | $27.73M | 0.6% | $14.49 | — | COM | 29428V104 |
| MIRM | MIRUM PHARMACEUTICALS INC | 1,496,525 | $26.13M | 0.6% | $12.84 | +53.1% | COM | 604749101 |
| INCY | INCYTE CORP | 300,000 | $26.09M | 0.6% | $72.84 | +18.8% | COM | 45337C102 |
| PRLD | PRELUDE THERAPEUTICS INC | 360,363 | $25.78M | 0.5% | $28.24 | +76.1% | COM | 74065P101 |
| GH | GUARDANT HEALTH INC | 200,000 | $25.78M | 0.5% | $42.73 | +169.3% | COM | 40131M109 |
| STTK | SHATTUCK LABS INC | 489,000 | $25.63M | 0.5% | $32.14 | 0.0% | COM | 82024L103 |
| TGTX | TG THERAPEUTICS INC | 489,000 | $25.44M | 0.5% | $16.11 | +109.8% | COM | 88322Q108 |
| — | KARUNA THERAPEUTICS INC | 243,950 | $24.78M | 0.5% | $38.33 | — | COM | 48576A100 |
| BIIB | BIOGEN INC | 100,000 | $24.49M | 0.5% | $303.47 | -14.6% | COM | 09062X103 |
| BAX | BAXTER INTL INC | 301,000 | $24.15M | 0.5% | $64.04 | +10.9% | COM | 071813109 |
| RPRX | ROYALTY PHARMA PLC | 480,000 | $24.02M | 0.5% | $49.50 | -14.3% | SHS CLASS A | G7709Q104 |
| SPRO | SPERO THERAPEUTICS INC | 1,235,000 | $23.95M | 0.5% | $11.82 | +31.9% | COM | 84833T103 |
| FOLD | AMICUS THERAPEUTICS INC | 1,029,000 | $23.76M | 0.5% | $11.49 | +78.0% | COM | 03152W109 |
| — | OAK STR HEALTH INC | 375,000 | $22.93M | 0.5% | $54.98 | — | COM | 67181A107 |
| — | SHOCKWAVE MED INC | 220,000 | $22.82M | 0.5% | $50.28 | — | COM | 82489T104 |
| BMRN | BIOMARIN PHARMACEUTICAL INC | 253,500 | $22.23M | 0.5% | $85.83 | -7.6% | COM | 09061G101 |
| COLL | COLLEGIUM PHARMACEUTICAL INC | 1,100,000 | $22.03M | 0.5% | $15.97 | +22.3% | COM | 19459J104 |
| RCKT | ROCKET PHARMACEUTICALS INC | 400,370 | $21.96M | 0.5% | $36.45 | 0.0% | COM | 77313F106 |
| — | ACCOLADE INC | 500,000 | $21.75M | 0.5% | $40.49 | — | COM | 00437E102 |
| — | AMARIN CORP PLC | 4,195,000 | $20.51M | 0.4% | $4.95 | — | SPONS ADR NEW | 023111206 |
| CHRS | COHERUS BIOSCIENCES INC | 1,162,500 | $20.2M | 0.4% | $18.69 | -4.8% | COM | 19249H103 |
| — | ABCAM PLC | 925,000 | $19.93M | 0.4% | $21.55 | — | ADS | 000380204 |
| — | PPD INC | 525,000 | $17.97M | 0.4% | $19.82 | — | COM | 69355F102 |
| — | GAMIDA CELL LTD | 2,094,000 | $17.57M | 0.4% | $4.95 | — | SHS | M47364100 |
| ACRS | ACLARIS THERAPEUTICS INC | 2,676,100 | $17.31M | 0.4% | $6.82 | -38.2% | COM | 00461U105 |
| — | CYTOKINETICS INC | 8,000,000 | $17.27M | 0.4% | $1.32 | — | NOTE 4.000%11/1 | 23282WAA8 |
| — | INOZYME PHARMA INC | 830,546 | $17.14M | 0.4% | $26.29 | — | COM | 45790W108 |
| RLAY | RELAY THERAPEUTICS INC | 412,000 | $17.12M | 0.4% | $38.13 | +18.6% | COM | 75943R102 |
| — | RIGEL PHARMACEUTICALS INC | 4,742,891 | $16.6M | 0.4% | $2.87 | — | COM NEW | 766559603 |
| KURA | KURA ONCOLOGY INC | 508,116 | $16.59M | 0.4% | $35.14 | 0.0% | COM | 50127T109 |
| — | CEREVEL THERAPEUTICS HLDNG I | 999,000 | $16.56M | 0.4% | $16.58 | — | COM | 15678U128 |
| GLPG | GALAPAGOS NV | 165,000 | $16.33M | 0.3% | $55.87 | — | SPON ADR | 36315X101 |
| — | INTERSECT ENT INC | 700,000 | $16.03M | 0.3% | $24.39 | — | COM | 46071F103 |
| TARA | PROTARA THERAPEUTICS INC | 643,200 | $15.57M | 0.3% | $23.19 | -7.0% | COM STK | 74365U107 |
| RYTM | RHYTHM PHARMACEUTICALS INC | 490,339 | $14.58M | 0.3% | $23.02 | +10.4% | COM | 76243J105 |
| JAZZ | JAZZ PHARMACEUTICALS PLC | 87,500 | $14.44M | 0.3% | $132.53 | +12.4% | SHS USD | G50871105 |
| — | MYOVANT SCIENCES LTD | 515,000 | $14.22M | 0.3% | $14.43 | — | COM | G637AM102 |
| — | GOSSAMER BIO INC | 15,573,000 | $14.18M | 0.3% | $1.01 | — | NOTE 5.000% 6/0 | 38341PAA0 |
| — | APPLIED THERAPEUTICS INC | 635,837 | $13.99M | 0.3% | $33.09 | — | COM | 03828A101 |
| — | GW PHARMACEUTICALS PLC | 119,188 | $13.76M | 0.3% | $113.94 | — | ADS | 36197T103 |
| CGEN | COMPUGEN LTD | 1,133,600 | $13.73M | 0.3% | $5.69 | +142.3% | ORD | M25722105 |
| PRTA | PROTHENA CORP PLC | 1,141,100 | $13.71M | 0.3% | $11.65 | +1.5% | SHS | G72800108 |
| — | AKERO THERAPEUTICS INC | 515,371 | $13.3M | 0.3% | $24.61 | — | COM | 00973Y108 |
| — | KINNATE BIOPHARMA INC | 324,686 | $12.92M | 0.3% | $39.78 | — | COM | 49705R105 |
| — | AEGLEA BIOTHERAPEUTICS INC | 1,580,000 | $12.44M | 0.3% | $7.80 | — | COM | 00773J103 |
| — | FIVE PRIME THERAPEUTICS INC | 721,633 | $12.28M | 0.3% | $16.74 | — | COM | 33830X104 |
| TBPH | THERAVANCE BIOPHARMA INC | 678,200 | $12.05M | 0.3% | $21.11 | -15.0% | COM | G8807B106 |
| — | TRANSLATE BIO INC | 643,500 | $11.86M | 0.3% | $12.61 | — | COM | 89374L104 |
| — | FIBROGEN INC | 309,387 | $11.47M | 0.2% | $30.22 | — | COM | 31572Q808 |
| — | FUSION PHARMACEUTICALS INC | 948,327 | $11.14M | 0.2% | $17.41 | — | COM | 36118A100 |
| — | NGM BIOPHARMACEUTICALS INC | 360,500 | $10.92M | 0.2% | $14.73 | — | COM | 62921N105 |
| TXG | 10X GENOMICS INC | 76,000 | $10.76M | 0.2% | $56.95 | +154.8% | CL A COM | 88025U109 |
| AUPH | AURINIA PHARMACEUTICALS INC | 773,669 | $10.7M | 0.2% | $14.49 | +0.5% | COM | 05156V102 |
| — | CHINOOK THERAPEUTICS INC | 668,849 | $10.61M | 0.2% | $15.86 | — | COM | 16961L106 |
| — | PARATEK PHARMACEUTICALS INC | 1,680,614 | $10.52M | 0.2% | $6.16 | — | COM | 699374302 |
| — | CHIASMA INC | 2,136,514 | $9.294M | 0.2% | $7.99 | — | COM | 16706W102 |
| — | TRILLIUM THERAPEUTICS INC | 618,500 | $9.098M | 0.2% | $4.22 | — | COM NEW | 89620X506 |
| — | SIERRA ONCOLOGY INC | 567,358 | $9.095M | 0.2% | $16.03 | — | COM NEW | 82640U404 |
| CNMD | CONMED CORP | 78,000 | $8.736M | 0.2% | $87.51 | +3.5% | COM | 207410101 |
| LEGN | LEGEND BIOTECH CORP | 309,418 | $8.713M | 0.2% | $38.15 | — | SPONSORED ADS | 52490G102 |
| NRIX | NURIX THERAPEUTICS INC | 257,250 | $8.458M | 0.2% | $25.20 | +31.5% | COM | 67080M103 |
| ADAPY | ADAPTIMMUNE THERAPEUTICS PLC | 1,545,000 | $8.328M | 0.2% | $10.05 | — | SPONDS ADR | 00653A107 |
| WST | WEST PHARMACEUTICAL SVSC INC | 28,500 | $8.074M | 0.2% | $96.51 | +187.1% | COM | 955306105 |
| — | IMARA INC | 360,500 | $7.949M | 0.2% | $16.03 | — | COM | 45249V107 |
| XENE | XENON PHARMACEUTICALS INC | 515,000 | $7.921M | 0.2% | $14.20 | -17.6% | COM | 98420N105 |
| QURE | UNIQURE NV | 208,500 | $7.533M | 0.2% | $56.07 | -24.8% | SHS | N90064101 |
| — | DYNAVAX TECHNOLOGIES CORP | 1,649,420 | $7.34M | 0.2% | $6.77 | — | COM NEW | 268158201 |
| — | ATRECA INC | 451,230 | $7.287M | 0.2% | $13.97 | — | CL A COM | 04965G109 |
| — | ODONATE THERAPEUTICS INC | 377,700 | $7.252M | 0.2% | $23.32 | — | COM | 676079106 |
| MGNX | MACROGENICS INC | 309,510 | $7.075M | 0.2% | $21.81 | +5.6% | COM | 556099109 |
| OSW | ONESPAWORLD HOLDINGS LIMITED | 690,000 | $6.997M | 0.1% | $11.16 | -30.1% | COM | P73684113 |
| — | INSMED INC | 6,000,000 | $6.763M | 0.1% | $0.89 | — | NOTE 1.750% 1/1 | 457669AA7 |
| — | CONSTELLATION PHARMCETICLS I | 232,743 | $6.703M | 0.1% | $37.77 | — | COM | 210373106 |
| ANAB | ANAPTYSBIO INC | 309,413 | $6.652M | 0.1% | $30.43 | -20.2% | COM | 032724106 |
| GRTX | GALERA THERAPEUTICS INC | 567,552 | $5.806M | 0.1% | $12.01 | -8.9% | COM | 36338D108 |
| — | ITEOS THERAPEUTICS INC | 159,957 | $5.41M | 0.1% | $24.67 | — | COM | 46565G104 |
| HQY | HEALTHEQUITY INC | 75,000 | $5.228M | 0.1% | $62.37 | -0.3% | COM | 42226A107 |
| — | PANACEA ACQUISITION CORP | 402,088 | $5.131M | 0.1% | $12.00 | — | UNIT 99/99/9999 | 698102209 |
| CERT | CERTARA INC | 150,000 | $5.058M | 0.1% | $36.62 | 0.0% | COM | 15687V109 |
| — | ACELRX PHARMACEUTICALS INC | 3,782,457 | $4.69M | 0.1% | $1.42 | — | COM | 00444T100 |
| — | PHASEBIO PHARMACEUTICALS INC | 1,314,374 | $4.416M | 0.1% | $6.05 | — | COM | 717224109 |
| — | BCLS ACQUISITION CORP | 309,000 | $3.442M | 0.1% | $11.14 | — | COM CL A | G0904B105 |
| — | RETROPHIN INC | 3,250,000 | $3.311M | 0.1% | $0.79 | — | NOTE 2.500% 9/1 | 761299AB2 |
| — | POSEIDA THERAPEUTICS INC | 289,754 | $3.179M | 0.1% | $8.87 | — | COM | 73730P108 |
| CORBF | GLOBAL CORD BLOOD CORPORATIO | 775,000 | $2.875M | 0.1% | $9.99 | -61.6% | SHS | G39342103 |
| — | LIFESCI ACQUISITION II CORP | 206,200 | $2.2M | 0.0% | $10.67 | — | COM | 53229E103 |
| — | EUCRATES BIOMEDICAL ACQU COR | 206,000 | $2.196M | 0.0% | $10.66 | — | UNIT 10/23/2027 | G3141W114 |
| — | JIYA ACQUISITION CORP | 206,200 | $2.124M | 0.0% | $10.30 | — | COM CL A | 47760M102 |
| — | TURMERIC ACQUISITION CORP | 206,000 | $2.116M | 0.0% | $10.27 | — | UNIT 10/08/2025 | G9127T116 |
| — | POPULATION HEALTH INVS CO IN | 201,044 | $2.101M | 0.0% | $10.45 | — | UNIT 99/99/9999 | G71716123 |
| MLTX | HELIX ACQUISITION CORP | 154,500 | $1.757M | 0.0% | $11.37 | — | COM CL A | G4444C102 |
| — | THERAVANCE BIOPHARMA INC | 1,500,000 | $1.42M | 0.0% | $1.14 | — | NOTE 3.250%11/0 | 88339KAA0 |
| — | NEUROCRINE BIOSCIENCES INC | 1,000,000 | $1.39M | 0.0% | $1.45 | — | NOTE 2.250% 5/1 | 64125CAD1 |
| — | RADIUS HEALTH INC | 1,500,000 | $1.348M | 0.0% | $1.01 | — | NOTE 3.000% 9/0 | 750469AA6 |
| — | PACIRA BIOSCIENCES INC | 1,000,000 | $1.149M | 0.0% | $0.91 | — | NOTE 2.375% 4/0 | 695127AD2 |
| ANNX | ANNEXON INC | 45,413 | $1.137M | 0.0% | $23.46 | +9.7% | COM | 03589W102 |
| — | NEVRO CORP | 500,000 | $912K | 0.0% | $1.37 | — | NOTE 2.750% 4/0 | 64157FAC7 |