LINEAGE CELL THERAPEUTICS IN

Institution	Shares	Value ($000)
Defender Capital, LLC.	6,829,099	$11,405
DEFINE FINANCIAL, LLC	20,000	$33
MARSHALL WACE, LLP	1,362,061	$2,275
OMERS ADMINISTRATION Corp	283,200	$473
Lighthouse Investment Partners, LLC	84,600	$141
ExodusPoint Capital Management, LP	181,694	$303
TWO SIGMA SECURITIES, LLC	23,598	$39
Voleon Capital Management LP	70,968	$119
SEI INVESTMENTS CO	269,311	$450
Qube Research & Technologies Ltd	211,348	$353
XTX Topco Ltd	42,281	$71
Point72 Asset Management, L.P.	159,408	$266
DLD Asset Management, LP	20,000	$33
Hudson Bay Capital Management LP	74,447	$124
Squarepoint Ops LLC	65,109	$109
STONERIDGE INVESTMENT PARTNERS LLC	12,540	$0
Schonfeld Strategic Advisors LLC	13,318	$22
BOOTHBAY FUND MANAGEMENT, LLC	10,000	$17
GROUP ONE TRADING, L.P.	6,503	$11
Larson Financial Group LLC	150	$0

Increased Positions (26)

RED CRANE WEALTH MANAGEMENT, LLC

Value ($000) $997 (+15.4%) Shares 597,263 (+16.8%)

BlackRock, Inc.

Value ($000) $6,403 (+69.8%) Shares 3,834,113 (+71.9%)

GOLDMAN SACHS GROUP INC

Value ($000) $2,403 (+882.7%) Shares 1,438,746 (+894.5%)

RENAISSANCE TECHNOLOGIES LLC

Value ($000) $4,016 (+24.7%) Shares 2,404,800 (+26.2%)

MORGAN STANLEY

Value ($000) $3,338 (+96.2%) Shares 1,998,663 (+98.6%)

JANE STREET GROUP, LLC

Value ($000) $1,678 (+585.4%) Shares 1,004,794 (+593.6%)

VANGUARD GROUP INC

Value ($000) $16,106 (+5.8%) Shares 9,644,276 (+7.1%)

SUSQUEHANNA INTERNATIONAL GROUP, LLP

Value ($000) $1,180 (+277.3%) Shares 706,415 (+281.8%)

CITADEL ADVISORS LLC

Value ($000) $847 (+158.3%) Shares 507,052 (+161.4%)

NWAM LLC

Value ($000) $99 (+72.1%) Shares 62,131 (+77.5%)

BARCLAYS PLC

Value ($000) $582 (+204.3%) Shares 348,510 (+64.9%)

CITIGROUP INC

Value ($000) $118 (+4871.9%) Shares 70,738 (+4931.2%)

STATE STREET CORP

Value ($000) $1,697 (+5.1%) Shares 1,016,211 (+6.3%)

GEODE CAPITAL MANAGEMENT, LLC

Value ($000) $4,112 (+0.5%) Shares 2,461,193 (+1.7%)

NORTHERN TRUST CORP

Value ($000) $800 (+6.8%) Shares 479,273 (+8.1%)

Jain Global LLC

Value ($000) $65 (+198.7%) Shares 38,851 (+202.3%)

Tower Research Capital LLC (TRC)

Value ($000) $33 (+441.7%) Shares 19,471 (+448.2%)

Kestra Advisory Services, LLC

Value ($000) $46 (+171.5%) Shares 27,747 (+174.7%)

BNP PARIBAS ARBITRAGE, SA

Value ($000) $27 (+9760.4%) Shares 15,942 (+9863.8%)

LPL Financial LLC

Value ($000) $46 (+14.1%) Shares 27,785 (+15.5%)

Institution	Prev Shares	Curr Shares	Change
RED CRANE WEALTH MANAGEMENT, LLC	511,363	597,263	+85,900 (+16.8%)
BlackRock, Inc.	2,230,756	3,834,113	+1,603,357 (+71.9%)
GOLDMAN SACHS GROUP INC	144,676	1,438,746	+1,294,070 (+894.5%)
RENAISSANCE TECHNOLOGIES LLC	1,905,633	2,404,800	+499,167 (+26.2%)
MORGAN STANLEY	1,006,451	1,998,663	+992,212 (+98.6%)
JANE STREET GROUP, LLC	144,863	1,004,794	+859,931 (+593.6%)
VANGUARD GROUP INC	9,006,930	9,644,276	+637,346 (+7.1%)
SUSQUEHANNA INTERNATIONAL GROUP, LLP	185,000	706,415	+521,415 (+281.8%)
CITADEL ADVISORS LLC	193,968	507,052	+313,084 (+161.4%)
NWAM LLC	35,000	62,131	+27,131 (+77.5%)
BARCLAYS PLC	211,300	348,510	+137,210 (+64.9%)
CITIGROUP INC	1,406	70,738	+69,332 (+4931.2%)
STATE STREET CORP	955,622	1,016,211	+60,589 (+6.3%)
GEODE CAPITAL MANAGEMENT, LLC	2,419,766	2,461,193	+41,427 (+1.7%)
NORTHERN TRUST CORP	443,352	479,273	+35,921 (+8.1%)
Jain Global LLC	12,851	38,851	+26,000 (+202.3%)
Tower Research Capital LLC (TRC)	3,552	19,471	+15,919 (+448.2%)
Kestra Advisory Services, LLC	10,100	27,747	+17,647 (+174.7%)
BNP PARIBAS ARBITRAGE, SA	160	15,942	+15,782 (+9863.8%)
LPL Financial LLC	24,066	27,785	+3,719 (+15.5%)

Decreased Positions (26)

GSA CAPITAL PARTNERS LLP

Value ($000) $1 (-51.2%) Shares 330,981 (-50.7%)

Quadrature Capital Ltd

Value ($000) $51 (-83.2%) Shares 30,632 (-82.9%)

MILLENNIUM MANAGEMENT LLC

Value ($000) $3,524 (-22.2%) Shares 2,110,419 (-21.3%)

SummitTX Capital, L.P.

Value ($000) $36 (-71.5%) Shares 21,319 (-71.1%)

IEQ CAPITAL, LLC

Value ($000) $39 (-85.6%) Shares 23,447 (-85.4%)

ROYAL BANK OF CANADA

Value ($000) $0 (-100.0%) Shares 236 (-99.9%)

TWO SIGMA INVESTMENTS, LP

Value ($000) $444 (-25.9%) Shares 265,585 (-25.0%)

CHARLES SCHWAB INVESTMENT MANAGEMENT INC

Value ($000) $217 (-41.2%) Shares 129,909 (-40.5%)

OSAIC HOLDINGS, INC.

Value ($000) $65 (-47.5%) Shares 38,683 (-54.4%)

BANK OF AMERICA CORP /DE/

Value ($000) $330 (-16.2%) Shares 197,849 (-15.2%)

UBS Group AG

Value ($000) $306 (-13.0%) Shares 183,127 (-12.0%)

Allworth Financial LP

Value ($000) $0 (-99.8%) Shares 22 (-99.8%)

RAYMOND JAMES FINANCIAL INC

Value ($000) $134 (-12.3%) Shares 80,185 (-11.3%)

WELLS FARGO & COMPANY/MN

Value ($000) $30 (-37.0%) Shares 17,937 (-36.3%)

Bank of New York Mellon Corp

Value ($000) $39 (-26.3%) Shares 23,213 (-25.4%)

JPMORGAN CHASE & CO

Value ($000) $16 (-30.6%) Shares 9,384 (-29.8%)

Jefferies Financial Group Inc.

Value ($000) $99 (-6.1%) Shares 59,090 (-5.0%)

FMR LLC

Value ($000) $321 (-2.2%) Shares 191,960 (-1.1%)

MAI Capital Management

Value ($000) $28 (-10.8%) Shares 16,621 (-9.8%)

ORG Partners LLC

Value ($000) $58 (-4.2%) Shares 34,600 (-3.1%)

Institution	Prev Shares	Curr Shares	Change
GSA CAPITAL PARTNERS LLP	670,856	330,981	-339,875 (-50.7%)
Quadrature Capital Ltd	179,031	30,632	-148,399 (-82.9%)
MILLENNIUM MANAGEMENT LLC	2,680,003	2,110,419	-569,584 (-21.3%)
SummitTX Capital, L.P.	73,835	21,319	-52,516 (-71.1%)
IEQ CAPITAL, LLC	160,413	23,447	-136,966 (-85.4%)
ROYAL BANK OF CANADA	306,272	236	-306,036 (-99.9%)
TWO SIGMA INVESTMENTS, LP	354,347	265,585	-88,762 (-25.0%)
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	218,274	129,909	-88,365 (-40.5%)
OSAIC HOLDINGS, INC.	84,796	38,683	-46,113 (-54.4%)
BANK OF AMERICA CORP /DE/	233,436	197,849	-35,587 (-15.2%)
UBS Group AG	208,080	183,127	-24,953 (-12.0%)
Allworth Financial LP	10,005	22	-9,983 (-99.8%)
RAYMOND JAMES FINANCIAL INC	90,381	80,185	-10,196 (-11.3%)
WELLS FARGO & COMPANY/MN	28,151	17,937	-10,214 (-36.3%)
Bank of New York Mellon Corp	31,134	23,213	-7,921 (-25.4%)
JPMORGAN CHASE & CO	13,369	9,384	-3,985 (-29.8%)
Jefferies Financial Group Inc.	62,200	59,090	-3,110 (-5.0%)
FMR LLC	194,028	191,960	-2,068 (-1.1%)
MAI Capital Management	18,417	16,621	-1,796 (-9.8%)
ORG Partners LLC	35,700	34,600	-1,100 (-3.1%)

Exited Positions (12)

Dauntless Investment Group, LLC

Value ($000) $2,728 Shares 1,614,100

R Squared Ltd

Value ($000) $20 Shares 11,823

Beacon Capital Management, LLC

Value ($000) $25 Shares 15,000

DIMENSIONAL FUND ADVISORS LP

Value ($000) $46 Shares 27,121

CITIZENS FINANCIAL GROUP INC/RI

Value ($000) $25 Shares 15,000

NewEdge Advisors, LLC

Value ($000) $19 Shares 11,500

AQR CAPITAL MANAGEMENT LLC

Value ($000) $20 Shares 11,650

EverSource Wealth Advisors, LLC

Value ($000) $0 Shares 288

Wealthspire Advisors, LLC

Value ($000) $0 Shares 88

SIMPLEX TRADING, LLC

Value ($000) $0 Shares 28,017

Steward Partners Investment Advisory, LLC

Value ($000) $0 Shares 11

Sound Income Strategies, LLC

Value ($000) $0 Shares 4

Institution	Prev Shares	Prev Value ($000)
Dauntless Investment Group, LLC	1,614,100	$2,728
R Squared Ltd	11,823	$20
Beacon Capital Management, LLC	15,000	$25
DIMENSIONAL FUND ADVISORS LP	27,121	$46
CITIZENS FINANCIAL GROUP INC/RI	15,000	$25
NewEdge Advisors, LLC	11,500	$19
AQR CAPITAL MANAGEMENT LLC	11,650	$20
EverSource Wealth Advisors, LLC	288	$0
Wealthspire Advisors, LLC	88	$0
SIMPLEX TRADING, LLC	28,017	$0
Steward Partners Investment Advisory, LLC	11	$0
Sound Income Strategies, LLC	4	$0