Location: Luxembourg
CIK: 0001053906 · Show all filings
Period: Q1 2018 (← Previous) (Next →)
Filing Date: May 10, 2018
Total Value: $7.991B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| — | BLUE BUFFALO PET PRODS INC | 87,460,875 | $3.482B | 43.6% | $17.91 | — | COM | 09531U102 |
| — | WEIGHT WATCHERS INTL INC NEW | 29,443,300 | $1.876B | 23.5% | $45.56 | — | COM | 948626106 |
| LXRX | LEXICON PHARMACEUTICALS INC | 58,274,650 | $499M | 6.2% | $7.38 | +25.2% | COM NEW | 528872302 |
| SPY | SPDR S&P 500 ETF TR | 500,000 | $132M | 1.6% | — | — | Call | 78462F103 |
| BAC | BANK AMER CORP | 4,350,000 | $130M | 1.6% | — | — | Call | 060505104 |
| GM | GENERAL MTRS CO | 3,500,000 | $127M | 1.6% | — | — | Call | 37045V100 |
| ONC | BEIGENE LTD | 600,000 | $101M | 1.3% | $108.47 | — | SPONSORED ADR | 07725L102 |
| IBM | INTERNATIONAL BUSINESS MACHS | 600,000 | $92.06M | 1.2% | — | — | Call | 459200101 |
| GS | GOLDMAN SACHS GROUP INC | 350,000 | $88.15M | 1.1% | — | — | Call | 38141G104 |
| XOM | EXXON MOBIL CORP | 1,000,000 | $74.61M | 0.9% | — | — | Call | 30231G102 |
| — | NEKTAR THERAPEUTICS | 700,000 | $74.38M | 0.9% | $53.65 | — | COM | 640268108 |
| ALNY | ALNYLAM PHARMACEUTICALS INC | 600,000 | $71.46M | 0.9% | $104.60 | +23.2% | COM | 02043Q107 |
| WFC | WELLS FARGO CO NEW | 1,300,000 | $68.13M | 0.9% | — | — | Call | 949746101 |
| — | CELGENE CORP | 650,000 | $57.99M | 0.7% | — | — | Call | 151020104 |
| CVX | CHEVRON CORP NEW | 500,000 | $57.02M | 0.7% | — | — | Call | 166764100 |
| BMY | BRISTOL MYERS SQUIBB CO | 900,000 | $56.92M | 0.7% | — | — | Call | 110122108 |
| — | ATARA BIOTHERAPEUTICS INC | 1,250,000 | $48.75M | 0.6% | $21.89 | — | COM | 046513107 |
| INCY | INCYTE CORP | 550,000 | $45.83M | 0.6% | $85.79 | +5.1% | Call | 45337C102 |
| XBI | SPDR SERIES TRUST | 500,000 | $43.87M | 0.5% | — | — | Call | 78464A870 |
| — | BLUEPRINT MEDICINES CORP | 450,000 | $41.27M | 0.5% | $88.08 | — | COM | 09627Y109 |
| AGIO | AGIOS PHARMACEUTICALS INC | 500,000 | $40.89M | 0.5% | $59.53 | +29.8% | COM | 00847X104 |
| FOLD | AMICUS THERAPEUTICS INC | 2,500,000 | $37.6M | 0.5% | $12.70 | +19.8% | COM | 03152W109 |
| — | TESARO INC | 600,000 | $34.28M | 0.4% | $69.27 | — | COM | 881569107 |
| — | ACCELERON PHARMA INC | 850,000 | $33.23M | 0.4% | $30.29 | — | COM | 00434H108 |
| — | ARRAY BIOPHARMA INC | 2,000,000 | $32.64M | 0.4% | $10.18 | — | COM | 04269X105 |
| CAT | CATERPILLAR INC DEL | 200,000 | $29.48M | 0.4% | — | — | Call | 149123101 |
| — | BLUEBIRD BIO INC | 150,000 | $25.61M | 0.3% | $71.42 | — | COM | 09609G100 |
| INCY | INCYTE CORP | 300,000 | $25M | 0.3% | $85.79 | +5.1% | COM | 45337C102 |
| — | MEDICINES CO | 700,000 | $23.06M | 0.3% | $38.99 | — | Call | 584688105 |
| — | NEKTAR THERAPEUTICS | 200,000 | $21.25M | 0.3% | $53.65 | — | Call | 640268108 |
| ANAB | ANAPTYSBIO INC | 190,000 | $19.77M | 0.2% | $43.31 | +160.2% | COM | 032724106 |
| — | AVEXIS INC | 160,000 | $19.77M | 0.2% | $56.50 | — | COM | 05366U100 |
| — | ALBIREO PHARMA INC | 547,841 | $17.84M | 0.2% | $28.75 | — | COM | 01345P106 |
| FCX | FREEPORT-MCMORAN INC | 1,000,000 | $17.57M | 0.2% | — | — | Call | 35671D857 |
| REGN | REGENERON PHARMACEUTICALS | 50,000 | $17.22M | 0.2% | — | — | Call | 75886F107 |
| — | ALEXION PHARMACEUTICALS INC | 150,000 | $16.72M | 0.2% | — | — | Call | 015351109 |
| VRTX | VERTEX PHARMACEUTICALS INC | 100,000 | $16.3M | 0.2% | — | — | Call | 92532F100 |
| BMRN | BIOMARIN PHARMACEUTICAL INC | 200,000 | $16.21M | 0.2% | — | — | Call | 09061G101 |
| — | SAGE THERAPEUTICS INC | 100,000 | $16.11M | 0.2% | $81.29 | — | COM | 78667J108 |
| FOLD | AMICUS THERAPEUTICS INC | 900,000 | $13.54M | 0.2% | $12.70 | +19.8% | Call | 03152W109 |
| — | CLOVIS ONCOLOGY INC | 250,000 | $13.2M | 0.2% | $84.84 | — | Call | 189464100 |
| — | AGENUS INC | 2,750,000 | $12.95M | 0.2% | $4.34 | — | COM NEW | 00847G705 |
| ARGX | ARGENX SE | 150,000 | $12.07M | 0.2% | $52.13 | — | SPONSORED ADR | 04016X101 |
| IQ | IQIYI INC | 750,000 | $11.66M | 0.1% | $15.55 | — | SPONSORED ADS | 46267X108 |
| — | FIBROGEN INC | 250,000 | $11.55M | 0.1% | $46.20 | — | COM | 31572Q808 |
| — | ACCELERATE DIAGNOSTICS INC | 500,000 | $11.43M | 0.1% | $26.66 | — | COM | 00430H102 |
| — | RADIUS HEALTH INC | 300,000 | $10.78M | 0.1% | $35.86 | — | COM NEW | 750469207 |
| — | GLOBAL BLOOD THERAPEUTICS IN | 200,000 | $9.66M | 0.1% | $27.74 | — | COM | 37890U108 |
| XNCR | XENCOR INC | 300,000 | $8.994M | 0.1% | $24.83 | +5.3% | COM | 98401F105 |
| — | ZAFGEN INC | 1,200,000 | $8.94M | 0.1% | $4.51 | — | COM | 98885E103 |
| — | LA JOLLA PHARMACEUTICAL CO | 300,000 | $8.934M | 0.1% | $29.78 | — | COM PAR $.0001 | 503459604 |
| DNLI | DENALI THERAPEUTICS INC | 450,000 | $8.861M | 0.1% | $17.97 | +14.4% | COM | 24823R105 |
| — | TESARO INC | 150,000 | $8.571M | 0.1% | $69.27 | — | Call | 881569107 |
| FATE | FATE THERAPEUTICS INC | 850,000 | $8.296M | 0.1% | $9.58 | 0.0% | COM | 31189P102 |
| NBIX | NEUROCRINE BIOSCIENCES INC | 100,000 | $8.293M | 0.1% | $46.00 | +83.6% | Call | 64125C109 |
| — | ZOGENIX INC | 200,000 | $8.01M | 0.1% | $40.05 | — | COM NEW | 98978L204 |
| IOVA | IOVANCE BIOTHERAPEUTICS INC | 460,000 | $7.774M | 0.1% | $15.14 | 0.0% | COM | 462260100 |
| RGNX | REGENXBIO INC | 250,000 | $7.463M | 0.1% | $22.34 | +30.3% | COM | 75901B107 |
| — | VITAL THERAPIES INC | 1,000,000 | $6.8M | 0.1% | $4.35 | — | COM | 92847R104 |
| — | MEDICINES CO | 200,000 | $6.588M | 0.1% | $38.99 | — | COM | 584688105 |
| ACIU | AC IMMUNE SA | 600,000 | $6.204M | 0.1% | $13.77 | -11.7% | SHS | H00263105 |
| — | STEMLINE THERAPEUTICS INC | 400,000 | $6.12M | 0.1% | $12.12 | — | COM | 85858C107 |
| WVE | WAVE LIFE SCIENCES LTD | 150,000 | $6.015M | 0.1% | $34.13 | +23.2% | SHS | Y95308105 |
| PRQR | PROQR THRAPEUTICS N V | 1,900,000 | $5.843M | 0.1% | $4.68 | -31.2% | SHS EURO | N71542109 |
| — | GLYCOMIMETICS INC | 325,000 | $5.275M | 0.1% | $13.15 | — | COM | 38000Q102 |
| MDGL | MADRIGAL PHARMACEUTICALS INC | 45,000 | $5.256M | 0.1% | $123.44 | 0.0% | COM | 558868105 |
| — | CYMABAY THERAPEUTICS INC | 400,000 | $5.196M | 0.1% | $12.99 | — | COM | 23257D103 |
| — | ADURO BIOTECH INC | 550,000 | $5.115M | 0.1% | $10.11 | — | COM | 00739L101 |
| — | IDERA PHARMACEUTICALS INC | 2,750,000 | $5.06M | 0.1% | $1.84 | — | COM NEW | 45168K306 |
| SPRO | SPERO THERAPEUTICS INC | 350,000 | $4.988M | 0.1% | $12.27 | -1.2% | COM | 84833T103 |
| — | DYNAVAX TECHNOLOGIES CORP | 250,000 | $4.963M | 0.1% | $20.80 | — | Call | 268158201 |
| RCKT | ROCKET PHARMACEUTICALS INC | 250,000 | $4.688M | 0.1% | $16.31 | 0.0% | COM | 77313F106 |
| RCUS | ARCUS BIOSCIENCES INC | 300,000 | $4.632M | 0.1% | $16.66 | 0.0% | COM | 03969F109 |
| — | BLUEPRINT MEDICINES CORP | 50,000 | $4.585M | 0.1% | $88.08 | — | Call | 09627Y109 |
| AKBA | AKEBIA THERAPEUTICS INC | 475,000 | $4.527M | 0.1% | $13.99 | 0.0% | COM | 00972D105 |
| — | AUDENTES THERAPEUTICS INC | 150,000 | $4.508M | 0.1% | $28.01 | — | COM | 05070R104 |
| NG | NOVAGOLD RES INC | 1,000,000 | $4.33M | 0.1% | $4.01 | 0.0% | COM NEW | 66987E206 |
| — | RESTORBIO INC | 450,000 | $4.311M | 0.1% | $9.58 | — | COM | 76133L103 |
| AGIO | AGIOS PHARMACEUTICALS INC | 50,000 | $4.089M | 0.1% | $59.53 | +29.8% | Call | 00847X104 |
| — | DICERNA PHARMACEUTICALS INC | 425,000 | $4.063M | 0.1% | $9.56 | — | COM | 253031108 |
| — | SYNLOGIC INC | 400,000 | $3.752M | 0.0% | $9.70 | — | COM | 87166L100 |
| IFRX | INFLARX NV | 125,000 | $3.605M | 0.0% | $26.36 | 0.0% | COM | N44821101 |
| TGTX | TG THERAPEUTICS INC | 250,000 | $3.55M | 0.0% | $11.19 | +14.2% | COM | 88322Q108 |
| — | MIRAGEN THERAPEUTICS INC | 500,000 | $3.505M | 0.0% | $7.44 | — | COM | 60463E103 |
| IRWD | IRONWOOD PHARMACEUTICALS INC | 216,879 | $3.346M | 0.0% | $13.01 | -4.2% | COM CL A | 46333X108 |
| — | PORTOLA PHARMACEUTICALS INC | 100,000 | $3.266M | 0.0% | $48.68 | — | COM | 737010108 |
| — | CLEMENTIA PHARMACEUTICALS IN | 200,000 | $3.03M | 0.0% | $15.15 | — | COM | 185575107 |
| SGMO | SANGAMO THERAPEUTICS INC | 150,000 | $2.85M | 0.0% | $21.38 | 0.0% | COM | 800677106 |
| — | ACHILLION PHARMACEUTICALS IN | 750,000 | $2.783M | 0.0% | $4.49 | — | COM | 00448Q201 |
| — | CHIMERIX INC | 500,000 | $2.6M | 0.0% | $5.54 | — | COM | 16934W106 |
| — | ADVERUM BIOTECHNOLOGIES INC | 400,000 | $2.32M | 0.0% | $5.80 | — | COM | 00773U108 |
| SNDX | SYNDAX PHARMACEUTICALS INC | 150,000 | $2.135M | 0.0% | $10.73 | -1.1% | COM | 87164F105 |
| — | MARINUS PHARMACEUTICALS INC | 500,000 | $1.91M | 0.0% | $5.56 | — | COM | 56854Q101 |
| NTLA | INTELLIA THERAPEUTICS INC | 90,000 | $1.898M | 0.0% | $24.09 | +2.1% | COM | 45826J105 |
| — | MINERVA NEUROSCIENCES INC | 300,000 | $1.875M | 0.0% | $12.43 | — | COM | 603380106 |
| KURA | KURA ONCOLOGY INC | 100,000 | $1.875M | 0.0% | $9.39 | +107.4% | COM | 50127T109 |
| — | HOMOLOGY MEDICINES INC | 100,000 | $1.87M | 0.0% | $18.70 | — | COM | 438083107 |
| KRYS | KRYSTAL BIOTECH INC | 150,000 | $1.514M | 0.0% | $10.06 | -2.0% | COM | 501147102 |
| — | ATYR PHARMA INC | 500,000 | $1.325M | 0.0% | $4.28 | — | COM | 002120103 |
| — | SELECTA BIOSCIENCES INC | 125,000 | $1.274M | 0.0% | $10.19 | — | COM | 816212104 |
| — | TOCAGEN INC | 100,000 | $1.185M | 0.0% | $10.25 | — | COM | 888846102 |
| CRSP | CRISPR THERAPEUTICS AG | 25,000 | $1.143M | 0.0% | $19.00 | +117.2% | NAMEN AKT | H17182108 |
| — | SOLID BIOSCIENCES INC | 150,000 | $1.125M | 0.0% | $7.50 | — | COM | 83422E105 |
| — | TRILLIUM THERAPEUTICS INC | 150,000 | $1.08M | 0.0% | $7.25 | — | COM NEW | 89620X506 |
| — | NOVAVAX INC | 500,000 | $1.05M | 0.0% | $2.08 | — | COM | 670002104 |
| — | NOVELION THERAPEUTICS INC | 256,400 | $897K | 0.0% | $8.42 | — | COM NEW | 67001K202 |
| EDIT | EDITAS MEDICINE INC | 25,000 | $829K | 0.0% | $25.18 | +41.5% | COM | 28106W103 |
| XENE | XENON PHARMACEUTICALS INC | 150,000 | $735K | 0.0% | $7.86 | -53.0% | COM | 98420N105 |
| — | ONCOCYTE CORPORATION | 150,000 | $315K | 0.0% | $5.38 | — | COM | 68235C107 |