Location: Luxembourg
CIK: 0001053906 · Show all filings
Period: Q2 2018 (← Previous) (Next →)
Filing Date: Aug 10, 2018
Total Value: $4.705B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| — | WEIGHT WATCHERS INTL INC NEW | 20,818,300 | $2.105B | 44.7% | $45.56 | — | COM | 948626106 |
| LXRX | LEXICON PHARMACEUTICALS INC | 60,240,864 | $723M | 15.4% | $7.48 | +36.8% | COM NEW | 528872302 |
| BAC | BANK AMER CORP | 6,350,000 | $179M | 3.8% | — | — | Call | 060505104 |
| — | CELGENE CORP | 2,000,000 | $159M | 3.4% | — | — | Call | 151020104 |
| ONC | BEIGENE LTD | 675,000 | $104M | 2.2% | $113.50 | — | SPONSORED ADR | 07725L102 |
| MS | MORGAN STANLEY | 1,500,000 | $71.1M | 1.5% | — | — | Call | 617446448 |
| BMY | BRISTOL MYERS SQUIBB CO | 1,250,000 | $69.17M | 1.5% | — | — | Call | 110122108 |
| GS | GOLDMAN SACHS GROUP INC | 300,000 | $66.17M | 1.4% | — | — | Call | 38141G104 |
| ALNY | ALNYLAM PHARMACEUTICALS INC | 650,000 | $64.02M | 1.4% | $104.18 | -4.8% | COM | 02043Q107 |
| GM | GENERAL MTRS CO | 1,500,000 | $59.1M | 1.3% | — | — | Call | 37045V100 |
| WFC | WELLS FARGO CO NEW | 1,000,000 | $55.44M | 1.2% | — | — | Call | 949746101 |
| IBB | ISHARES TR | 450,000 | $49.42M | 1.1% | — | — | Call | 464287556 |
| — | ACCELERON PHARMA INC | 1,000,000 | $48.52M | 1.0% | $33.02 | — | COM | 00434H108 |
| FOLD | AMICUS THERAPEUTICS INC | 2,900,000 | $45.3M | 1.0% | $13.04 | +16.0% | COM | 03152W109 |
| — | BLUEPRINT MEDICINES CORP | 700,000 | $44.44M | 0.9% | $79.29 | — | COM | 09627Y109 |
| — | NEKTAR THERAPEUTICS | 900,000 | $43.95M | 0.9% | $52.58 | — | COM | 640268108 |
| SRRK | SCHOLAR ROCK HLDG CORP | 2,396,040 | $37.38M | 0.8% | $18.88 | 0.0% | COM | 80706P103 |
| — | ATARA BIOTHERAPEUTICS INC | 1,000,000 | $36.75M | 0.8% | $21.89 | — | COM | 046513107 |
| — | TESARO INC | 800,000 | $35.58M | 0.8% | $63.07 | — | COM | 881569107 |
| — | ARRAY BIOPHARMA INC | 2,000,000 | $33.56M | 0.7% | $10.18 | — | COM | 04269X105 |
| AGIO | AGIOS PHARMACEUTICALS INC | 350,000 | $29.48M | 0.6% | $59.53 | +46.5% | COM | 00847X104 |
| — | BLUEBIRD BIO INC | 170,000 | $26.68M | 0.6% | $81.48 | — | COM | 09609G100 |
| — | MEDICINES CO | 700,000 | $25.69M | 0.5% | $37.84 | — | Call | 584688105 |
| — | ZOGENIX INC | 500,000 | $22.1M | 0.5% | $42.54 | — | COM NEW | 98978L204 |
| FATE | FATE THERAPEUTICS INC | 1,700,000 | $19.28M | 0.4% | $10.30 | +7.0% | COM | 31189P102 |
| BMRN | BIOMARIN PHARMACEUTICAL INC | 200,000 | $18.84M | 0.4% | — | — | Call | 09061G101 |
| — | ALBIREO PHARMA INC | 500,000 | $17.75M | 0.4% | $28.75 | — | COM | 01345P106 |
| FCX | FREEPORT-MCMORAN INC | 1,000,000 | $17.26M | 0.4% | — | — | Call | 35671D857 |
| IFRX | INFLARX NV | 500,000 | $16.13M | 0.3% | $32.50 | +6.3% | COM | N44821101 |
| — | SAGE THERAPEUTICS INC | 100,000 | $15.65M | 0.3% | $81.29 | — | COM | 78667J108 |
| — | FIBROGEN INC | 250,000 | $15.65M | 0.3% | $46.20 | — | COM | 31572Q808 |
| — | TESARO INC | 350,000 | $15.56M | 0.3% | $63.07 | — | Call | 881569107 |
| XNCR | XENCOR INC | 400,000 | $14.8M | 0.3% | $27.24 | +26.5% | COM | 98401F105 |
| — | MEDICINES CO | 400,000 | $14.68M | 0.3% | $37.84 | — | COM | 584688105 |
| — | NEKTAR THERAPEUTICS | 300,000 | $14.65M | 0.3% | $52.58 | — | Call | 640268108 |
| ANAB | ANAPTYSBIO INC | 200,000 | $14.21M | 0.3% | $45.34 | +85.0% | COM | 032724106 |
| AUTL | AUTOLUS THERAPEUTICS PLC | 525,000 | $14.06M | 0.3% | $26.79 | — | SPON ADS | 05280R100 |
| MDGL | MADRIGAL PHARMACEUTICALS INC | 50,000 | $13.98M | 0.3% | $128.66 | +36.5% | COM | 558868105 |
| — | BLUEPRINT MEDICINES CORP | 200,000 | $12.7M | 0.3% | $79.29 | — | Call | 09627Y109 |
| ARGX | ARGENX SE | 150,000 | $12.43M | 0.3% | $52.13 | — | SPONSORED ADR | 04016X101 |
| — | ZAFGEN INC | 1,200,000 | $12.28M | 0.3% | $4.51 | — | COM | 98885E103 |
| — | ACCELERATE DIAGNOSTICS INC | 500,000 | $11.15M | 0.2% | $26.66 | — | COM | 00430H102 |
| — | ACCELERATE DIAGNOSTICS INC | 500,000 | $11.15M | 0.2% | $26.66 | — | Call | 00430H102 |
| PRQR | PROQR THRAPEUTICS N V | 1,500,000 | $10.95M | 0.2% | $4.68 | +7.9% | SHS EURO | N71542109 |
| RGNX | REGENXBIO INC | 150,000 | $10.76M | 0.2% | $22.34 | +113.7% | COM | 75901B107 |
| EXEL | EXELIXIS INC | 500,000 | $10.76M | 0.2% | — | — | Call | 30161Q104 |
| — | CYMABAY THERAPEUTICS INC | 800,000 | $10.74M | 0.2% | $13.21 | — | COM | 23257D103 |
| ALNY | ALNYLAM PHARMACEUTICALS INC | 100,000 | $9.849M | 0.2% | $104.18 | -4.8% | Call | 02043Q107 |
| — | GLOBAL BLOOD THERAPEUTICS IN | 200,000 | $9.04M | 0.2% | $27.74 | — | COM | 37890U108 |
| — | AUDENTES THERAPEUTICS INC | 236,000 | $9.018M | 0.2% | $31.73 | — | COM | 05070R104 |
| IOVA | IOVANCE BIOTHERAPEUTICS INC | 700,000 | $8.96M | 0.2% | $14.96 | -2.3% | COM | 462260100 |
| — | SOLID BIOSCIENCES INC | 250,000 | $8.908M | 0.2% | $18.75 | — | COM | 83422E105 |
| RCKT | ROCKET PHARMACEUTICALS INC | 400,000 | $7.852M | 0.2% | $17.29 | +9.4% | COM | 77313F106 |
| — | BLUEBIRD BIO INC | 50,000 | $7.848M | 0.2% | $81.48 | — | Call | 09609G100 |
| FOLD | AMICUS THERAPEUTICS INC | 500,000 | $7.81M | 0.2% | $13.04 | +16.0% | Call | 03152W109 |
| DNLI | DENALI THERAPEUTICS INC | 500,000 | $7.625M | 0.2% | $18.06 | +4.3% | COM | 24823R105 |
| — | LA JOLLA PHARMACEUTICAL CO | 250,000 | $7.293M | 0.2% | $29.78 | — | COM PAR $.0001 2 | 503459604 |
| — | VITAL THERAPIES INC | 1,000,000 | $6.85M | 0.1% | $4.35 | — | COM | 92847R104 |
| — | SELECTA BIOSCIENCES INC | 500,000 | $6.625M | 0.1% | $12.49 | — | COM | 816212104 |
| — | AERPIO PHARMACEUTICALS INC | 1,558,400 | $6.467M | 0.1% | $4.15 | — | COM | 00810B105 |
| — | STEMLINE THERAPEUTICS INC | 400,000 | $6.42M | 0.1% | $12.12 | — | COM | 85858C107 |
| — | TRANSLATE BIO INC | 500,000 | $6.325M | 0.1% | $12.65 | — | COM | 89374L104 |
| — | AGENUS INC | 2,750,000 | $6.243M | 0.1% | $4.34 | — | COM NEW | 00847G705 |
| ACIU | AC IMMUNE SA | 600,000 | $5.592M | 0.1% | $13.77 | -28.2% | SHS | H00263105 |
| TGTX | TG THERAPEUTICS INC | 400,000 | $5.26M | 0.1% | $12.15 | +13.2% | COM | 88322Q108 |
| — | DICERNA PHARMACEUTICALS INC | 425,000 | $5.206M | 0.1% | $9.56 | — | COM | 253031108 |
| SPRO | SPERO THERAPEUTICS INC | 350,000 | $5.135M | 0.1% | $12.27 | +4.2% | COM | 84833T103 |
| — | RESTORBIO INC | 550,000 | $5.033M | 0.1% | $9.50 | — | COM | 76133L103 |
| — | ACCELERON PHARMA INC | 100,000 | $4.852M | 0.1% | $33.02 | — | Call | 00434H108 |
| AKBA | AKEBIA THERAPEUTICS INC | 475,000 | $4.741M | 0.1% | $13.99 | -28.4% | COM | 00972D105 |
| — | CLOVIS ONCOLOGY INC | 100,000 | $4.547M | 0.1% | — | — | Call | 189464100 |
| AGIO | AGIOS PHARMACEUTICALS INC | 50,000 | $4.212M | 0.1% | $59.53 | +46.5% | Call | 00847X104 |
| IRWD | IRONWOOD PHARMACEUTICALS INC | 216,879 | $4.147M | 0.1% | $13.01 | +13.8% | COM CL A | 46333X108 |
| — | GLYCOMIMETICS INC | 250,000 | $4.033M | 0.1% | $13.15 | — | COM | 38000Q102 |
| — | SYNLOGIC INC | 400,000 | $3.932M | 0.1% | $9.70 | — | COM | 87166L100 |
| — | ADURO BIOTECH INC | 550,000 | $3.85M | 0.1% | $10.11 | — | COM | 00739L101 |
| WVE | WAVE LIFE SCIENCES LTD | 100,000 | $3.825M | 0.1% | $34.13 | +26.1% | SHS | Y95308105 |
| — | DYNAVAX TECHNOLOGIES CORP | 250,000 | $3.813M | 0.1% | — | — | Call | 268158201 |
| RCUS | ARCUS BIOSCIENCES INC | 300,000 | $3.672M | 0.1% | $16.66 | -5.8% | COM | 03969F109 |
| — | IDERA PHARMACEUTICALS INC | 2,750,000 | $3.63M | 0.1% | $1.84 | — | COM NEW | 45168K306 |
| — | AVROBIO INC | 125,000 | $3.57M | 0.1% | $28.56 | — | COM | 05455M100 |
| — | MARINUS PHARMACEUTICALS INC | 500,000 | $3.535M | 0.1% | $5.56 | — | COM | 56854Q101 |
| — | MIRAGEN THERAPEUTICS INC | 500,000 | $3.205M | 0.1% | $7.44 | — | COM | 60463E103 |
| — | UNITY BIOTECHNOLOGY INC | 200,000 | $3.012M | 0.1% | $15.06 | — | COM | 91381U101 |
| — | TRICIDA INC | 100,000 | $2.99M | 0.1% | $29.90 | — | COM | 89610F101 |
| CRSP | CRISPR THERAPEUTICS AG | 50,000 | $2.938M | 0.1% | $37.98 | +50.0% | NAMEN AKT | H17182108 |
| SGMO | SANGAMO THERAPEUTICS INC | 200,000 | $2.84M | 0.1% | $20.19 | -17.7% | COM | 800677106 |
| — | MAGENTA THERAPEUTICS INC | 200,000 | $2.7M | 0.1% | $13.50 | — | COM | 55910K108 |
| — | CLEMENTIA PHARMACEUTICALS IN | 200,000 | $2.632M | 0.1% | $15.15 | — | COM | 185575107 |
| NTLA | INTELLIA THERAPEUTICS INC | 90,000 | $2.462M | 0.1% | $24.09 | +0.6% | COM | 45826J105 |
| — | CHIMERIX INC | 500,000 | $2.38M | 0.1% | $5.54 | — | COM | 16934W106 |
| KRYS | KRYSTAL BIOTECH INC | 150,000 | $2.231M | 0.0% | $10.06 | +11.5% | COM | 501147102 |
| — | ADVERUM BIOTECHNOLOGIES INC | 400,000 | $2.12M | 0.0% | $5.80 | — | COM | 00773U108 |
| — | HOMOLOGY MEDICINES INC | 100,000 | $2.04M | 0.0% | $18.70 | — | COM | 438083107 |
| — | KINIKSA PHARMACEUTICALS LTD | 100,000 | $1.735M | 0.0% | $17.35 | — | COM CL A | G5269C101 |
| SNNAQ | SIENNA BIOPHARMACEUTICALS IN | 99,000 | $1.504M | 0.0% | $16.98 | 0.0% | COM | 82622H108 |
| XENE | XENON PHARMACEUTICALS INC | 150,000 | $1.38M | 0.0% | $7.86 | -21.0% | COM | 98420N105 |
| — | NOVELION THERAPEUTICS INC | 256,400 | $944K | 0.0% | $8.42 | — | COM NEW | 67001K202 |
| — | TOCAGEN INC | 100,000 | $934K | 0.0% | $10.25 | — | COM | 888846102 |
| — | TRILLIUM THERAPEUTICS INC | 150,000 | $900K | 0.0% | $7.25 | — | COM NEW | 89620X506 |
| — | NOVAVAX INC | 500,000 | $670K | 0.0% | $2.08 | — | COM | 670002104 |
| — | ATYR PHARMA INC | 500,000 | $455K | 0.0% | $4.28 | — | COM | 002120103 |
| SNDX | SYNDAX PHARMACEUTICALS INC | 60,697 | $426K | 0.0% | $10.73 | -8.6% | COM | 87164F105 |
| — | ONCOCYTE CORPORATION | 150,000 | $383K | 0.0% | $5.38 | — | COM | 68235C107 |