Location: Luxembourg
CIK: 0001053906 · Show all filings
Period: Q3 2018 (← Previous) (Next →)
Filing Date: Nov 9, 2018
Total Value: $3.844B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| — | WEIGHT WATCHERS INTL INC NEW | 14,818,300 | $1.067B | 27.8% | $45.56 | — | COM | 948626106 |
| LXRX | LEXICON PHARMACEUTICALS INC | 60,240,864 | $643M | 16.7% | $7.48 | +53.3% | COM NEW | 528872302 |
| GS | GOLDMAN SACHS GROUP INC | 1,050,000 | $235M | 6.1% | — | — | Call | 38141G104 |
| BAC | BANK AMER CORP | 4,500,000 | $133M | 3.4% | — | — | Call | 060505104 |
| ONC | BEIGENE LTD | 600,000 | $103M | 2.7% | $113.50 | — | SPONSORED ADR | 07725L102 |
| GM | GENERAL MTRS CO | 3,000,000 | $101M | 2.6% | — | — | Call | 37045V100 |
| MS | MORGAN STANLEY | 2,000,000 | $93.14M | 2.4% | — | — | Call | 617446448 |
| WFC | WELLS FARGO CO NEW | 1,500,000 | $78.84M | 2.1% | — | — | Call | 949746101 |
| — | RUBIUS THERAPEUTICS INC | 2,908,791 | $69.81M | 1.8% | $24.00 | — | COM | 78116T103 |
| — | CELGENE CORP | 750,000 | $67.12M | 1.7% | — | — | Call | 151020104 |
| SRRK | SCHOLAR ROCK HLDG CORP | 2,396,040 | $61.7M | 1.6% | $18.88 | -2.7% | COM | 80706P103 |
| — | ACCELERON PHARMA INC | 1,000,000 | $57.23M | 1.5% | $33.02 | — | COM | 00434H108 |
| ALNY | ALNYLAM PHARMACEUTICALS INC | 600,000 | $52.51M | 1.4% | $104.18 | -3.5% | COM | 02043Q107 |
| — | NEKTAR THERAPEUTICS | 800,000 | $48.77M | 1.3% | $52.58 | — | COM | 640268108 |
| FOLD | AMICUS THERAPEUTICS INC | 4,000,000 | $48.36M | 1.3% | $13.30 | +5.2% | COM | 03152W109 |
| BMY | BRISTOL MYERS SQUIBB CO | 750,000 | $46.56M | 1.2% | — | — | Call | 110122108 |
| — | ATARA BIOTHERAPEUTICS INC | 1,000,000 | $41.35M | 1.1% | $21.89 | — | COM | 046513107 |
| — | BLUEPRINT MEDICINES CORP | 500,000 | $39.03M | 1.0% | $79.29 | — | COM | 09627Y109 |
| FATE | FATE THERAPEUTICS INC | 2,190,000 | $35.67M | 0.9% | $10.64 | +11.1% | COM | 31189P102 |
| — | TESARO INC | 800,000 | $31.21M | 0.8% | $63.07 | — | COM | 881569107 |
| ANAB | ANAPTYSBIO INC | 300,000 | $29.93M | 0.8% | $57.88 | +43.3% | COM | 032724106 |
| — | ARRAY BIOPHARMA INC | 1,900,000 | $28.88M | 0.8% | $10.18 | — | COM | 04269X105 |
| — | BLUEBIRD BIO INC | 175,000 | $25.55M | 0.7% | $83.33 | — | COM | 09609G100 |
| PRQR | PROQR THRAPEUTICS N V | 1,300,000 | $25.16M | 0.7% | $4.68 | +127.3% | SHS EURO | N71542109 |
| AGIO | AGIOS PHARMACEUTICALS INC | 300,000 | $23.14M | 0.6% | $59.53 | +35.1% | COM | 00847X104 |
| — | ZOGENIX INC | 400,000 | $19.84M | 0.5% | $42.54 | — | COM NEW | 98978L204 |
| — | TESARO INC | 500,000 | $19.5M | 0.5% | $63.07 | — | Call | 881569107 |
| XNCR | XENCOR INC | 500,000 | $19.48M | 0.5% | $29.95 | +36.2% | COM | 98401F105 |
| BMRN | BIOMARIN PHARMACEUTICAL INC | 200,000 | $19.39M | 0.5% | — | — | Call | 09061G101 |
| XBI | SPDR SERIES TRUST | 200,000 | $19.17M | 0.5% | — | — | Call | 78464A870 |
| MU | MICRON TECHNOLOGY INC | 400,000 | $18.09M | 0.5% | — | — | Call | 595112103 |
| — | MEDICINES CO | 600,000 | $17.95M | 0.5% | $37.84 | — | Call | 584688105 |
| C | CITIGROUP INC | 250,000 | $17.93M | 0.5% | — | — | Call | 172967424 |
| IFRX | INFLARX NV | 500,000 | $17.16M | 0.4% | $32.50 | -0.7% | COM | N44821101 |
| — | ALBIREO PHARMA INC | 500,000 | $16.48M | 0.4% | $28.75 | — | COM | 01345P106 |
| BABA | ALIBABA GROUP HLDG LTD | 100,000 | $16.48M | 0.4% | $164.75 | — | Call | 01609W102 |
| AUTL | AUTOLUS THERAPEUTICS PLC | 500,000 | $15.34M | 0.4% | $26.79 | — | SPON ADS | 05280R100 |
| — | FIBROGEN INC | 250,000 | $15.19M | 0.4% | $46.20 | — | COM | 31572Q808 |
| — | SAGE THERAPEUTICS INC | 100,000 | $14.13M | 0.4% | $81.29 | — | COM | 78667J108 |
| ARGX | ARGENX SE | 185,000 | $14.03M | 0.4% | $56.62 | — | SPONSORED ADR | 04016X101 |
| FCX | FREEPORT-MCMORAN INC | 1,000,000 | $13.92M | 0.4% | — | — | Call | 35671D857 |
| WYNN | WYNN RESORTS LTD | 100,000 | $12.71M | 0.3% | — | — | Call | 983134107 |
| AAL | AMERICAN AIRLS GROUP INC | 300,000 | $12.4M | 0.3% | — | — | Call | 02376R102 |
| — | NEKTAR THERAPEUTICS | 200,000 | $12.19M | 0.3% | $52.58 | — | Call | 640268108 |
| FOLD | AMICUS THERAPEUTICS INC | 1,000,000 | $12.09M | 0.3% | $13.30 | +5.2% | Call | 03152W109 |
| — | MEDICINES CO | 400,000 | $11.96M | 0.3% | $37.84 | — | COM | 584688105 |
| — | ACCELERATE DIAGNOSTICS INC | 500,000 | $11.47M | 0.3% | $26.66 | — | COM | 00430H102 |
| — | ACCELERATE DIAGNOSTICS INC | 500,000 | $11.47M | 0.3% | $26.66 | — | Call | 00430H102 |
| RGNX | REGENXBIO INC | 150,000 | $11.32M | 0.3% | $22.34 | +222.5% | COM | 75901B107 |
| DNLI | DENALI THERAPEUTICS INC | 500,000 | $10.87M | 0.3% | $18.06 | -8.4% | COM | 24823R105 |
| BABA | ALIBABA GROUP HLDG LTD | 65,000 | $10.71M | 0.3% | $164.75 | — | SPONSORED ADS | 01609W102 |
| MDGL | MADRIGAL PHARMACEUTICALS INC | 50,000 | $10.71M | 0.3% | $128.66 | +95.0% | COM | 558868105 |
| — | SOLID BIOSCIENCES INC | 225,000 | $10.62M | 0.3% | $18.75 | — | COM | 83422E105 |
| NIO | NIO INC | 1,500,000 | $10.47M | 0.3% | $6.98 | — | SPON ADS | 62914V106 |
| — | AUDENTES THERAPEUTICS INC | 250,000 | $9.898M | 0.3% | $32.17 | — | COM | 05070R104 |
| RCKT | ROCKET PHARMACEUTICALS INC | 400,000 | $9.848M | 0.3% | $17.29 | +25.5% | COM | 77313F106 |
| — | ZAFGEN INC | 800,000 | $9.352M | 0.2% | $4.51 | — | COM | 98885E103 |
| — | CYMABAY THERAPEUTICS INC | 800,000 | $8.864M | 0.2% | $13.21 | — | COM | 23257D103 |
| ALNY | ALNYLAM PHARMACEUTICALS INC | 100,000 | $8.752M | 0.2% | $104.18 | -3.5% | Call | 02043Q107 |
| — | SELECTA BIOSCIENCES INC | 561,540 | $8.732M | 0.2% | $12.82 | — | COM | 816212104 |
| IOVA | IOVANCE BIOTHERAPEUTICS INC | 700,000 | $7.875M | 0.2% | $14.96 | -5.1% | COM | 462260100 |
| — | CLEMENTIA PHARMACEUTICALS IN | 692,000 | $7.716M | 0.2% | $12.31 | — | COM | 185575107 |
| — | RESTORBIO INC | 500,000 | $7.57M | 0.2% | $9.50 | — | COM | 76133L103 |
| REPL | REPLIMUNE GROUP INC | 450,000 | $7.245M | 0.2% | $17.53 | 0.0% | COM | 76029N106 |
| — | STEMLINE THERAPEUTICS INC | 400,000 | $6.64M | 0.2% | $12.12 | — | COM | 85858C107 |
| — | DICERNA PHARMACEUTICALS INC | 425,000 | $6.486M | 0.2% | $9.56 | — | COM | 253031108 |
| SPRO | SPERO THERAPEUTICS INC | 600,000 | $6.306M | 0.2% | $12.00 | -3.3% | COM | 84833T103 |
| — | 111 INC | 450,000 | $6.084M | 0.2% | $13.52 | — | ADS | 68247Q102 |
| ACIU | AC IMMUNE SA | 750,000 | $6M | 0.2% | $13.02 | -22.8% | SHS | H00263105 |
| — | TRANSLATE BIO INC | 600,000 | $6M | 0.2% | $12.21 | — | COM | 89374L104 |
| — | AGENUS INC | 2,750,000 | $5.885M | 0.2% | $4.34 | — | COM NEW | 00847G705 |
| — | LOGMEIN INC | 65,000 | $5.792M | 0.2% | $89.11 | — | COM | 54142L109 |
| CRNX | CRINETICS PHARMACEUTICALS IN | 200,000 | $5.73M | 0.1% | $29.69 | 0.0% | COM | 22663K107 |
| — | AVROBIO INC | 100,000 | $5.187M | 0.1% | $28.56 | — | COM | 05455M100 |
| SGMO | SANGAMO THERAPEUTICS INC | 300,000 | $5.085M | 0.1% | $18.52 | -17.9% | COM | 800677106 |
| — | MARINUS PHARMACEUTICALS INC | 500,000 | $5M | 0.1% | $5.56 | — | COM | 56854Q101 |
| — | AERPIO PHARMACEUTICALS INC | 1,558,400 | $4.815M | 0.1% | $4.15 | — | COM | 00810B105 |
| CRSP | CRISPR THERAPEUTICS AG | 100,000 | $4.435M | 0.1% | $45.18 | +15.9% | NAMEN AKT | H17182108 |
| AKBA | AKEBIA THERAPEUTICS INC | 475,000 | $4.194M | 0.1% | $13.99 | -36.1% | COM | 00972D105 |
| RCUS | ARCUS BIOSCIENCES INC | 300,000 | $4.182M | 0.1% | $16.66 | -23.4% | COM | 03969F109 |
| — | ADURO BIOTECH INC | 550,000 | $4.043M | 0.1% | $10.11 | — | COM | 00739L101 |
| — | LA JOLLA PHARMACEUTICAL CO | 200,000 | $4.026M | 0.1% | $29.78 | — | COM PAR $.0001 2 | 503459604 |
| — | Y MABS THERAPEUTICS INC | 150,000 | $3.984M | 0.1% | $26.56 | — | COM | 984241109 |
| — | CHIMERIX INC | 1,000,000 | $3.89M | 0.1% | $4.71 | — | COM | 16934W106 |
| ELAN | ELANCO ANIMAL HEALTH INC | 100,000 | $3.489M | 0.1% | $35.17 | 0.0% | COM | 28414H103 |
| XENE | XENON PHARMACEUTICALS INC | 250,000 | $3.3M | 0.1% | $9.35 | +23.9% | COM | 98420N105 |
| FLEX | FLEX LTD | 250,000 | $3.28M | 0.1% | $10.47 | 0.0% | ORD | Y2573F102 |
| — | TRICIDA INC | 100,000 | $3.055M | 0.1% | $29.90 | — | COM | 89610F101 |
| — | CONATUS PHARMACEUTICALS INC | 500,000 | $2.9M | 0.1% | $5.80 | — | COM | 20600T108 |
| — | GRITSTONE ONCOLOGY INC | 200,000 | $2.848M | 0.1% | $14.24 | — | COM | 39868T105 |
| — | SYNLOGIC INC | 200,000 | $2.842M | 0.1% | $9.70 | — | COM | 87166L100 |
| — | MIRAGEN THERAPEUTICS INC | 500,000 | $2.79M | 0.1% | $7.44 | — | COM | 60463E103 |
| KRYS | KRYSTAL BIOTECH INC | 150,000 | $2.637M | 0.1% | $10.06 | +66.8% | COM | 501147102 |
| NTLA | INTELLIA THERAPEUTICS INC | 90,000 | $2.576M | 0.1% | $24.09 | +20.8% | COM | 45826J105 |
| — | ADVERUM BIOTECHNOLOGIES INC | 400,000 | $2.42M | 0.1% | $5.80 | — | COM | 00773U108 |
| — | MAGENTA THERAPEUTICS INC | 200,000 | $2.402M | 0.1% | $13.50 | — | COM | 55910K108 |
| — | HOMOLOGY MEDICINES INC | 100,000 | $2.286M | 0.1% | $18.70 | — | COM | 438083107 |
| TGTX | TG THERAPEUTICS INC | 400,000 | $2.24M | 0.1% | $12.15 | -6.0% | COM | 88322Q108 |
| IRWD | IRONWOOD PHARMACEUTICALS INC | 110,532 | $2.04M | 0.1% | $13.01 | +21.5% | COM CL A | 46333X108 |
| — | NOVAVAX INC | 500,000 | $940K | 0.0% | $2.08 | — | COM | 670002104 |
| — | TRILLIUM THERAPEUTICS INC | 150,000 | $870K | 0.0% | $7.25 | — | COM NEW | 89620X506 |
| — | UNITY BIOTECHNOLOGY INC | 50,000 | $815K | 0.0% | $15.06 | — | COM | 91381U101 |
| — | NOVELION THERAPEUTICS INC | 256,400 | $759K | 0.0% | $8.42 | — | COM NEW | 67001K202 |
| — | ATYR PHARMA INC | 500,000 | $406K | 0.0% | $4.28 | — | COM | 002120103 |
| — | ONCOCYTE CORPORATION | 150,000 | $375K | 0.0% | $5.38 | — | COM | 68235C107 |