Location: Luxembourg
CIK: 0001053906 · Show all filings
Period: Q4 2018 (← Previous) (Next →)
Filing Date: Feb 11, 2019
Total Value: $2.7B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| — | WEIGHT WATCHERS INTL INC NEW | 14,818,300 | $571M | 21.2% | $45.56 | — | COM | 948626106 |
| LXRX | LEXICON PHARMACEUTICALS INC | 60,240,864 | $400M | 14.8% | $7.48 | +8.4% | COM NEW | 528872302 |
| GM | GENERAL MTRS CO | 3,500,000 | $117M | 4.3% | — | — | Call | 37045V100 |
| BAC | BANK AMER CORP | 4,500,000 | $111M | 4.1% | — | — | Call | 060505104 |
| ONC | BEIGENE LTD | 600,000 | $84.16M | 3.1% | $113.50 | — | SPONSORED ADR | 07725L102 |
| MRNA | MODERNA INC | 5,256,298 | $80.26M | 3.0% | $16.43 | 0.0% | COM | 60770K107 |
| WFC | WELLS FARGO CO NEW | 1,500,000 | $69.12M | 2.6% | — | — | Call | 949746101 |
| — | CELGENE CORP | 1,000,000 | $64.09M | 2.4% | — | — | Call | 151020104 |
| MS | MORGAN STANLEY | 1,500,000 | $59.48M | 2.2% | — | — | Call | 617446448 |
| BABA | ALIBABA GROUP HLDG LTD | 412,000 | $56.47M | 2.1% | $141.44 | — | SPONSORED ADS | 01609W102 |
| SRRK | SCHOLAR ROCK HLDG CORP | 2,296,040 | $52.74M | 2.0% | $18.88 | +19.8% | COM | 80706P103 |
| — | RUBIUS THERAPEUTICS INC | 2,908,791 | $46.77M | 1.7% | $24.00 | — | COM | 78116T103 |
| — | ACCELERON PHARMA INC | 1,050,000 | $45.73M | 1.7% | $33.52 | — | COM | 00434H108 |
| GS | GOLDMAN SACHS GROUP INC | 250,000 | $41.76M | 1.5% | — | — | Call | 38141G104 |
| ALNY | ALNYLAM PHARMACEUTICALS INC | 500,000 | $36.45M | 1.4% | $104.18 | -26.2% | COM | 02043Q107 |
| NIO | NIO INC | 5,600,000 | $35.67M | 1.3% | $6.53 | — | SPONSORED ADS | 62914V106 |
| — | ARRAY BIOPHARMA INC | 2,500,000 | $35.63M | 1.3% | $11.16 | — | COM | 04269X105 |
| — | ATARA BIOTHERAPEUTICS INC | 1,000,000 | $34.74M | 1.3% | $21.89 | — | COM | 046513107 |
| — | BLUEPRINT MEDICINES CORP | 600,000 | $32.35M | 1.2% | $75.06 | — | COM | 09627Y109 |
| FOLD | AMICUS THERAPEUTICS INC | 3,000,000 | $28.74M | 1.1% | $13.30 | -17.3% | COM | 03152W109 |
| BMY | BRISTOL MYERS SQUIBB CO | 550,000 | $28.59M | 1.1% | — | — | Call | 110122108 |
| ONC | BEIGENE LTD | 200,000 | $28.05M | 1.0% | $113.50 | — | Call | 07725L102 |
| FATE | FATE THERAPEUTICS INC | 2,150,000 | $27.59M | 1.0% | $10.64 | +31.0% | COM | 31189P102 |
| — | NEKTAR THERAPEUTICS | 800,000 | $26.3M | 1.0% | $52.58 | — | COM | 640268108 |
| ARGX | ARGENX SE | 270,000 | $25.94M | 1.0% | $69.04 | — | SPONSORED ADR | 04016X101 |
| PRQR | PROQR THRAPEUTICS N V | 1,400,000 | $22.09M | 0.8% | $5.65 | +224.7% | SHS EURO | N71542109 |
| ALNY | ALNYLAM PHARMACEUTICALS INC | 300,000 | $21.87M | 0.8% | $104.18 | -26.2% | Call | 02043Q107 |
| FCX | FREEPORT-MCMORAN INC | 2,000,000 | $20.62M | 0.8% | — | — | Call | 35671D857 |
| AGIO | AGIOS PHARMACEUTICALS INC | 400,000 | $18.44M | 0.7% | $60.08 | +2.7% | COM | 00847X104 |
| IFRX | INFLARX NV | 500,000 | $18.18M | 0.7% | $32.50 | -5.3% | COM | N44821101 |
| XNCR | XENCOR INC | 500,000 | $18.08M | 0.7% | $29.95 | +22.5% | COM | 98401F105 |
| — | BLUEBIRD BIO INC | 175,000 | $17.36M | 0.6% | $83.33 | — | COM | 09609G100 |
| BMRN | BIOMARIN PHARMACEUTICAL INC | 200,000 | $17.03M | 0.6% | — | — | Call | 09061G101 |
| AUTL | AUTOLUS THERAPEUTICS PLC | 475,000 | $15.6M | 0.6% | $26.79 | — | SPONSORED ADS | 05280R100 |
| — | FIBROGEN INC | 300,000 | $13.88M | 0.5% | $46.21 | — | COM | 31572Q808 |
| — | SOLID BIOSCIENCES INC | 500,000 | $13.4M | 0.5% | $23.18 | — | COM | 83422E105 |
| — | AUDENTES THERAPEUTICS INC | 600,000 | $12.79M | 0.5% | $25.84 | — | COM | 05070R104 |
| MU | MICRON TECHNOLOGY INC | 400,000 | $12.69M | 0.5% | — | — | Call | 595112103 |
| — | ALBIREO PHARMA INC | 500,000 | $12.27M | 0.5% | $28.75 | — | COM | 01345P106 |
| — | MEDICINES CO | 600,000 | $11.48M | 0.4% | $37.84 | — | Call | 584688105 |
| ALLO | ALLOGENE THERAPEUTICS INC | 400,000 | $10.77M | 0.4% | $26.57 | 0.0% | COM | 019770106 |
| DNLI | DENALI THERAPEUTICS INC | 500,000 | $10.33M | 0.4% | $18.06 | +0.4% | COM | 24823R105 |
| — | CLEMENTIA PHARMACEUTICALS IN | 850,000 | $9.996M | 0.4% | $12.20 | — | COM | 185575107 |
| — | BLUEBIRD BIO INC | 100,000 | $9.92M | 0.4% | $83.33 | — | Call | 09609G100 |
| WYNN | WYNN RESORTS LTD | 100,000 | $9.891M | 0.4% | — | — | Call | 983134107 |
| AAL | AMERICAN AIRLS GROUP INC | 300,000 | $9.633M | 0.4% | — | — | Call | 02376R102 |
| — | SAGE THERAPEUTICS INC | 100,000 | $9.579M | 0.4% | $81.29 | — | COM | 78667J108 |
| ANAB | ANAPTYSBIO INC | 150,000 | $9.569M | 0.4% | $57.88 | +28.5% | COM | 032724106 |
| AGIO | AGIOS PHARMACEUTICALS INC | 200,000 | $9.222M | 0.3% | $60.08 | +2.7% | Call | 00847X104 |
| MLCO | MELCO RESORT ENTERTAINMENT L | 500,000 | $8.81M | 0.3% | — | — | Call | 585464100 |
| — | ACCELERON PHARMA INC | 200,000 | $8.71M | 0.3% | $33.52 | — | Call | 00434H108 |
| MDGL | MADRIGAL PHARMACEUTICALS INC | 70,000 | $7.89M | 0.3% | $136.12 | +13.7% | COM | 558868105 |
| — | MEDICINES CO | 400,000 | $7.656M | 0.3% | $37.84 | — | COM | 584688105 |
| VICI | VICI PPTYS INC | 400,000 | $7.512M | 0.3% | $14.27 | 0.0% | COM | 925652109 |
| — | ZOGENIX INC | 200,000 | $7.292M | 0.3% | $42.54 | — | COM NEW | 98978L204 |
| RGNX | REGENXBIO INC | 170,000 | $7.132M | 0.3% | $26.62 | +120.4% | COM | 75901B107 |
| ACIU | AC IMMUNE SA | 750,000 | $7.088M | 0.3% | $13.02 | -27.5% | SHS | H00263105 |
| — | FIBROGEN INC | 150,000 | $6.942M | 0.3% | $46.21 | — | Call | 31572Q808 |
| VALE | VALE S A | 500,000 | $6.595M | 0.2% | — | — | Call | 91912E105 |
| — | NEKTAR THERAPEUTICS | 200,000 | $6.574M | 0.2% | $52.58 | — | Call | 640268108 |
| — | AGENUS INC | 2,750,000 | $6.545M | 0.2% | $4.34 | — | COM NEW | 00847G705 |
| NIO | NIO INC | 1,000,000 | $6.37M | 0.2% | $6.53 | — | Call | 62914V106 |
| CRNX | CRINETICS PHARMACEUTICALS IN | 200,000 | $5.998M | 0.2% | $29.69 | -5.2% | COM | 22663K107 |
| RCKT | ROCKET PHARMACEUTICALS INC | 400,000 | $5.928M | 0.2% | $17.29 | -4.0% | COM | 77313F106 |
| — | ACCELERATE DIAGNOSTICS INC | 500,000 | $5.75M | 0.2% | $26.66 | — | COM | 00430H102 |
| KRYS | KRYSTAL BIOTECH INC | 275,000 | $5.715M | 0.2% | $15.01 | +39.5% | COM | 501147102 |
| — | DICERNA PHARMACEUTICALS INC | 525,000 | $5.612M | 0.2% | $9.78 | — | COM | 253031108 |
| FOLD | AMICUS THERAPEUTICS INC | 500,000 | $4.79M | 0.2% | $13.30 | -17.3% | Call | 03152W109 |
| SGMO | SANGAMO THERAPEUTICS INC | 400,000 | $4.592M | 0.2% | $17.00 | -26.9% | COM | 800677106 |
| REPL | REPLIMUNE GROUP INC | 450,000 | $4.5M | 0.2% | $17.53 | -22.9% | COM | 76029N106 |
| — | TRANSLATE BIO INC | 600,000 | $4.5M | 0.2% | $12.21 | — | COM | 89374L104 |
| IOVA | IOVANCE BIOTHERAPEUTICS INC | 500,000 | $4.425M | 0.2% | $14.96 | -35.5% | COM | 462260100 |
| CRSP | CRISPR THERAPEUTICS AG | 145,000 | $4.143M | 0.2% | $41.95 | -17.1% | NAMEN AKT | H17182108 |
| — | CYMABAY THERAPEUTICS INC | 500,000 | $3.935M | 0.1% | $13.21 | — | COM | 23257D103 |
| — | STEMLINE THERAPEUTICS INC | 400,000 | $3.8M | 0.1% | $12.12 | — | COM | 85858C107 |
| SPRO | SPERO THERAPEUTICS INC | 600,000 | $3.69M | 0.1% | $12.00 | -32.5% | COM | 84833T103 |
| — | CLOVIS ONCOLOGY INC | 200,000 | $3.592M | 0.1% | — | — | Call | 189464100 |
| — | ZAFGEN INC | 700,000 | $3.465M | 0.1% | $4.51 | — | COM | 98885E103 |
| TWST | TWIST BIOSCIENCE CORP | 150,000 | $3.464M | 0.1% | $22.16 | 0.0% | COM | 90184D100 |
| — | RESTORBIO INC | 400,000 | $3.448M | 0.1% | $9.50 | — | COM | 76133L103 |
| RCUS | ARCUS BIOSCIENCES INC | 300,000 | $3.231M | 0.1% | $16.66 | -29.9% | COM | 03969F109 |
| Z | ZILLOW GROUP INC | 100,000 | $3.158M | 0.1% | $35.51 | 0.0% | CL C CAP STK | 98954M200 |
| — | GRITSTONE ONCOLOGY INC | 200,000 | $3.09M | 0.1% | $14.24 | — | COM | 39868T105 |
| — | TRICIDA INC | 125,000 | $2.948M | 0.1% | $28.64 | — | COM | 89610F101 |
| — | MERUS N V | 206,125 | $2.886M | 0.1% | $14.00 | — | COM | N5749R100 |
| — | 111 INC | 450,000 | $2.763M | 0.1% | $13.52 | — | ADS | 68247Q102 |
| — | AERPIO PHARMACEUTICALS INC | 1,558,400 | $2.649M | 0.1% | $4.15 | — | COM | 00810B105 |
| — | ADURO BIOTECH INC | 1,000,000 | $2.64M | 0.1% | $6.75 | — | COM | 00739L101 |
| AKBA | AKEBIA THERAPEUTICS INC | 475,000 | $2.627M | 0.1% | $13.99 | -44.1% | COM | 00972D105 |
| — | CHIMERIX INC | 1,000,000 | $2.57M | 0.1% | $4.71 | — | COM | 16934W106 |
| CTMX | CYTOMX THERAPEUTICS INC | 150,000 | $2.265M | 0.1% | $14.84 | 0.0% | COM | 23284F105 |
| — | HOMOLOGY MEDICINES INC | 100,000 | $2.236M | 0.1% | $18.70 | — | COM | 438083107 |
| — | MOMENTA PHARMACEUTICALS INC | 200,000 | $2.208M | 0.1% | $11.04 | — | COM | 60877T100 |
| — | ALDER BIOPHARMACEUTICALS INC | 200,000 | $2.05M | 0.1% | $10.25 | — | COM | 014339105 |
| — | AVROBIO INC | 100,000 | $1.665M | 0.1% | $28.56 | — | COM | 05455M100 |
| TGTX | TG THERAPEUTICS INC | 400,000 | $1.64M | 0.1% | $12.15 | -59.1% | COM | 88322Q108 |
| — | SELECTA BIOSCIENCES INC | 600,000 | $1.596M | 0.1% | $12.17 | — | COM | 816212104 |
| — | MIRAGEN THERAPEUTICS INC | 500,000 | $1.515M | 0.1% | $7.44 | — | COM | 60463E103 |
| — | MARINUS PHARMACEUTICALS INC | 500,000 | $1.435M | 0.1% | $5.56 | — | COM | 56854Q101 |
| IRWD | IRONWOOD PHARMACEUTICALS INC | 110,532 | $1.145M | 0.0% | $13.01 | -11.8% | COM CL A | 46333X108 |
| — | MAGENTA THERAPEUTICS INC | 200,000 | $1.14M | 0.0% | $13.50 | — | COM | 55910K108 |
| — | Y MABS THERAPEUTICS INC | 50,000 | $1.017M | 0.0% | $26.56 | — | COM | 984241109 |
| — | TRILLIUM THERAPEUTICS INC | 150,000 | $257K | 0.0% | $7.25 | — | COM NEW | 89620X506 |
| — | NOVELION THERAPEUTICS INC | 256,400 | $215K | 0.0% | $8.42 | — | COM NEW | 67001K202 |