Location: Boston, MA
CIK: 0001346824 · Show all filings
Period: Q4 2020 (← Previous) (Next →)
Filing Date: Feb 16, 2021
Total Value: $7.154B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Share Price | Est. Cost/Share | Unrealized @ Report Date | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|---|
| ASND | ASCENDIS PHARMA A S | 5,865,338 | $978M | 13.7% | $166.78 | $53.69 | — | SPONSORED ADR | 04351P101 |
| TGTX | TG THERAPEUTICS INC | 8,685,471 | $452M | 6.3% | $52.02 * | $11.95 | +182.7% | COM | 88322Q108 |
| NVAX | NOVAVAX INC | 3,788,564 | $422M | 5.9% | $111.51 * | $84.76 | +25.4% | COM NEW | 670002401 |
| NKTX | NKARTA INC | 5,605,129 | $345M | 4.8% | $61.47 * | $29.47 | +40.9% | COM | 65487U108 |
| — | FORMA THERAPEUTICS HLDGS INC | 9,011,651 | $315M | 4.4% | $34.90 | $46.49 | — | SHS | 34633R104 |
| ARVN | ARVINAS INC | 3,672,872 | $312M | 4.4% | $84.93 * | $23.47 | +46.9% | COM | 04335A105 |
| — | CHEMOCENTRYX INC | 4,776,548 | $296M | 4.1% | $61.92 | $42.10 | — | COM | 16383L106 |
| AVIR | ATEA PHARMACEUTICALS INC | 5,368,451 | $224M | 3.1% | $41.78 * | $32.23 | 0.0% | COM | 04683R106 |
| — | ITEOS THERAPEUTICS INC | 4,417,258 | $149M | 2.1% | $33.82 | $24.67 | — | COM | 46565G104 |
| — | KINNATE BIOPHARMA INC | 3,593,052 | $143M | 2.0% | $39.78 | $39.78 | — | COM | 49705R105 |
| AXSM | AXSOME THERAPEUTICS INC | 1,655,447 | $135M | 1.9% | $81.47 * | $68.14 | +9.7% | COM | 05464T104 |
| KROS | KEROS THERAPEUTICS INC | 1,875,000 | $132M | 1.8% | $70.54 * | $30.81 | +104.5% | COM | 492327101 |
| PHAT | PHATHOM PHARMACEUTICALS INC | 3,825,008 | $127M | 1.8% | $33.22 * | $25.67 | +57.8% | COM | 71722W107 |
| RYTM | RHYTHM PHARMACEUTICALS INC | 4,179,067 | $124M | 1.7% | $29.73 * | $24.09 | +5.5% | COM | 76243J105 |
| TVTX | TRAVERE THERAPEUTICS INC | 4,557,867 | $124M | 1.7% | $27.26 * | $23.35 | 0.0% | COM | 89422G107 |
| — | IMMUNOGEN INC | 18,417,458 | $119M | 1.7% | $6.45 | $5.36 | — | COM | 45253H101 |
| RCKT | ROCKET PHARMACEUTICALS INC COM | 2,136,081 | $117M | 1.6% | $54.84 * | $36.45 | 0.0% | COM | 77313F106 |
| — | 89BIO INC | 4,736,214 | $115M | 1.6% | $24.37 | $26.08 | — | COM | 282559103 |
| — | ZOGENIX INC | 5,345,631 | $107M | 1.5% | $19.99 | $26.04 | — | COM NEW | 98978L204 |
| PMVP | PMV PHARMACEUTICALS INC | 1,710,265 | $105M | 1.5% | $61.51 * | $36.80 | +6.6% | COM | 69353Y103 |
| OLMA | OLEMA PHARMACEUTICALS INC | 2,150,404 | $103M | 1.4% | $48.08 * | $46.89 | 0.0% | COM | 68062P106 |
| — | ADVERUM BIOTECHNOLOGIES INC | 9,502,383 | $103M | 1.4% | $10.84 | $10.49 | — | COM | 00773U108 |
| MGNX | MACROGENICS INC | 4,375,217 | $100M | 1.4% | $22.86 | $17.37 | +32.5% | COM | 556099109 |
| PCVX | VAXCYTE INC | 3,710,699 | $98.59M | 1.4% | $26.57 * | $32.16 | +15.6% | COM | 92243G108 |
| — | IGM BIOSCIENCES INC | 982,723 | $86.77M | 1.2% | $88.29 | $28.47 | — | COM | 449585108 |
| BDTX | BLACK DIAMOND THERAPEUTICS INC | 2,589,904 | $83.01M | 1.2% | $32.05 * | $30.22 | +8.7% | COM | 09203E105 |
| SPRY | SILVERBACK THERAPEUTICS INC | 1,742,186 | $80.73M | 1.1% | $46.34 * | $33.40 | 0.0% | COM | 82835W108 |
| — | TRILLIUM THERAPEUTICS INC | 5,290,481 | $77.82M | 1.1% | $14.71 | $4.04 | — | COM NEW | 89620X506 |
| — | SOLID BIOSCIENCES INC | 9,976,569 | $75.62M | 1.1% | $7.58 | $8.08 | — | COM | 83422E105 |
| — | KALA PHARMACEUTICALS INC | 10,874,613 | $73.73M | 1.0% | $6.78 | $10.65 | — | COM | 483119103 |
| — | FIVE PRIME THERAPEUTICS INC | 4,285,161 | $72.89M | 1.0% | $17.01 | $17.01 | — | COM | 33830X104 |
| — | INHIBRX INC | 2,129,003 | $70.19M | 1.0% | $32.97 | $18.00 | — | COM | 45720L107 |
| LEGN | LEGEND BIOTECH CORP | 2,408,292 | $67.82M | 0.9% | $28.16 | $42.56 | — | SPONSORED ADS | 52490G102 |
| — | CURIS INC | 7,707,790 | $63.13M | 0.9% | $8.19 | $8.19 | — | COM NEW | 231269200 |
| WVE | WAVE LIFE SCIENCES LTD | 7,775,207 | $61.19M | 0.9% | $7.87 * | $17.26 | -51.4% | SHS | Y95308105 |
| CRDF | CARDIFF ONCOLOGY INC | 3,290,000 | $59.19M | 0.8% | $17.99 * | $6.60 | +166.2% | COM | 14147L108 |
| DYN | DYNE THERAPEUTICS INC | 2,805,045 | $58.91M | 0.8% | $21.00 * | $21.96 | -9.9% | COM | 26818M108 |
| — | CONSTELLATION PHARMCETICLS INC | 1,852,746 | $53.36M | 0.7% | $28.80 | $28.80 | — | COM | 210373106 |
| PACB | PACIFIC BIOSCIENCES OF CALIFORNIA INC | 1,987,997 | $51.57M | 0.7% | $25.94 * | $16.99 | 0.0% | COM | 69404D108 |
| GERN | GERON CORP | 30,126,299 | $47.9M | 0.7% | $1.59 * | $1.49 | +21.9% | COM | 374163103 |
| — | SUTRO BIOPHARMA INC | 2,118,212 | $45.99M | 0.6% | $21.71 | $7.97 | — | COM | 869367102 |
| CCCC | C4 THERAPEUTICS INC | 1,377,569 | $45.64M | 0.6% | $33.13 * | $29.00 | 0.0% | COM STK | 12529R107 |
| — | AKOUOS INC | 2,281,249 | $45.24M | 0.6% | $19.83 | $22.50 | — | COM | 00973J101 |
| RLAY | RELAY THERAPEUTICS INC | 1,000,000 | $41.56M | 0.6% | $41.56 * | $38.13 | +18.6% | COM | 75943R102 |
| — | INOZYME PHARMA INC | 2,003,653 | $41.35M | 0.6% | $20.64 | $26.29 | — | COM | 45790W108 |
| — | ORCHARD THERAPEUTICS PLC | 12,315,213 | $41.16M | 0.6% | $3.34 | $10.43 | — | ADS | 68570P101 |
| ARDX | ARDELYX INC | 6,163,086 | $39.88M | 0.6% | $6.47 * | $6.19 | -4.2% | COM | 039697107 |
| — | CEREVEL THERAPEUTICS HLDNG INC | 2,200,000 | $36.48M | 0.5% | $16.58 | $16.58 | — | COM | 15678U128 |
| ARQT | ARCUTIS BIOTHERAPEUTICS INC | 1,165,184 | $32.78M | 0.5% | $28.13 * | $26.87 | -8.8% | COM | 03969K108 |
| LRMR | LARIMAR THERAPEUTICS INC | 1,515,151 | $32.44M | 0.5% | $21.41 * | $11.65 | +72.1% | COM | 517125100 |
| — | VERONA PHARMA PLC | 5,100,000 | $31.82M | 0.4% | $6.24 | $6.24 | — | SPONSORED ADS | 925050106 |
| — | PANDION THERAPEUTICS INC | 1,770,023 | $26.29M | 0.4% | $14.85 | $11.46 | — | COM | 698340106 |
| ALEC | ALECTOR INC | 1,616,879 | $24.46M | 0.3% | $15.13 * | $23.90 | -48.0% | COM | 014442107 |
| — | CONCERT PHARMACEUTICALS INC | 1,823,520 | $23.05M | 0.3% | $12.64 | $8.84 | — | COM | 206022105 |
| SNDX | SYNDAX PHARMACEUTICALS INC | 1,023,067 | $22.75M | 0.3% | $22.24 * | $15.23 | +36.2% | COM | 87164F105 |
| — | SATSUMA PHARMACEUTICALS INC | 4,681,858 | $21.58M | 0.3% | $4.61 | $15.01 | — | COM | 80405P107 |
| ORIC | ORIC PHARMACEUTICALS INC | 584,000 | $19.77M | 0.3% | $33.85 * | $28.69 | 0.0% | COM | 68622P109 |
| — | SCPHARMACEUTICALS INC | 3,518,998 | $18.61M | 0.3% | $5.29 | $10.74 | — | COM | 810648105 |
| — | MARINUS PHARMACEUTICALS INC | 1,300,000 | $15.86M | 0.2% | $12.20 | $12.20 | — | COM NEW | 56854Q200 |
| VXRT | VAXART INC | 2,742,271 | $15.66M | 0.2% | $5.71 * | $8.91 | -28.6% | COM NEW | 92243A200 |
| MIST | MILESTONE PHARMACEUTICALS INC | 2,327,714 | $15.6M | 0.2% | $6.70 | $7.17 | -6.6% | COM | 59935V107 |
| OCUL | OCULAR THERAPEUTIX INC | 750,000 | $15.53M | 0.2% | $20.70 * | $6.63 | +124.1% | COM | 67576A100 |
| — | BCTG ACQUISITION CORP | 1,250,000 | $14.3M | 0.2% | $11.44 | $10.36 | — | COM | 05492W103 |
| — | REPARE THERAPEUTICS INC | 409,000 | $14.03M | 0.2% | $34.30 | $31.02 | — | COM | 760273102 |
| — | BCLS ACQUISITION CORP | 1,250,000 | $13.93M | 0.2% | $11.14 | $11.14 | — | COM CL A | G0904B105 |
| ADAPY | ADAPTIMMUNE THERAPEUTICS PLC | 2,499,025 | $13.47M | 0.2% | $5.39 | $3.01 | — | SPONDS ADR | 00653A107 |
| COGT | COGENT BIOSCIENCES INC | 1,025,641 | $11.52M | 0.2% | $11.23 * | $10.99 | 0.0% | COM | 19240Q201 |
| — | ARYA SCIENCES ACQUISITION CO | 1,000,000 | $10.85M | 0.2% | $10.85 | $10.81 | — | COM CL A | G3166W106 |
| — | FRAZIER LIFESCIENCES ACQUISITION CO | 1,000,000 | $10.38M | 0.1% | $10.38 | $10.38 | — | UNIT 12/09/2025 | G3710A121 |
| — | THERAPEUTICSMD INC | 7,812,500 | $9.453M | 0.1% | $1.21 | $1.21 | — | COM | 88338N107 |
| — | LYRA THERAPEUTICS INC | 815,849 | $9.301M | 0.1% | $11.40 | $11.34 | — | COM | 55234L105 |
| — | PASSAGE BIO INC | 322,630 | $8.25M | 0.1% | $25.57 | $15.75 | — | COM | 702712100 |
| — | HEALTH SCIENCES ACQ CORP 2 | 625,000 | $8.006M | 0.1% | $12.81 | $11.00 | — | ORD SHS | G4411D109 |
| CRNX | CRINETICS PHARMACEUTICALS INC | 564,102 | $7.959M | 0.1% | $14.11 | $27.24 | -48.9% | COM | 22663K107 |
| MLTX | HELIX ACQUISITION CORP | 700,000 | $7.959M | 0.1% | $11.37 | $11.37 | — | COM CL A | G4444C102 |
| — | 5 01 ACQUISITION CORP | 750,000 | $7.628M | 0.1% | $10.17 | $10.17 | — | COM CL A | 33836P105 |
| — | MIRAGEN THERAPEUTICS INC | 451,932 | $7.434M | 0.1% | $16.45 | $16.45 | — | COM NEW | 60463E202 |
| — | IMARA INC | 248,804 | $5.486M | 0.1% | $22.05 | $16.03 | — | COM | 45249V107 |
| PROF | PROFOUND MEDICAL CORP | 192,311 | $3.954M | 0.1% | $20.56 * | $18.40 | 0.0% | COM NEW | 74319B502 |
| — | X4 PHARMACEUTICALS INC | 536,962 | $3.453M | 0.0% | $6.43 | $12.24 | — | COM | 98420X103 |
| — | CEREVEL THERAPEUTICS HLDNG INC | 233,333 | $1.318M | 0.0% | $5.65 | $5.65 | — | *W EXP 06/09/2027 | 15678U102 |
| OVID | OVID THERAPEUTICS INC | 285,000 | $658K | 0.0% | $2.31 * | $4.68 | -0.3% | COM | 690469101 |