Location: Boston, MA
CIK: 0001346824 · Show all filings
Period: Q2 2022 (← Previous) (Next →)
Filing Date: Aug 15, 2022
Total Value: $3.751B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Share Price | Est. Cost/Share | Unrealized @ Report Date | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|---|
| ASND | ASCENDIS PHARMA A/S | 7,567,900 | $704M | 18.8% | $92.96 | $73.22 | — | SPONSORED ADR | 04351P101 |
| BIIB | BIOGEN INC | 727,024 | $148M | 4.0% | $203.94 | $217.46 | -6.0% | COM | 09062X103 |
| CTKB | CYTEK BIOSCIENCES INC | 13,381,054 | $144M | 3.8% | $10.73 * | $20.70 | -51.9% | COM | 23285D109 |
| — | AEROVATE THERAPEUTICS INC | 8,263,982 | $129M | 3.4% | $15.63 | $22.83 | — | COM | 008064107 |
| DAWN | DAY ONE BIOPHARMACEUTICALS I | 7,040,622 | $126M | 3.4% | $17.90 * | $18.13 | -43.1% | COM | 23954D109 |
| TVTX | TRAVERE THERAPEUTICS INC | 4,922,941 | $119M | 3.2% | $24.23 * | $24.15 | +4.1% | COM | 89422G107 |
| JANX | JANUX THERAPEUTICS INC | 8,670,644 | $106M | 2.8% | $12.21 * | $22.27 | -46.8% | COM | 47103J105 |
| PCVX | VAXCYTE INC | 4,581,203 | $99.69M | 2.7% | $21.76 * | $30.49 | -24.1% | COM | 92243G108 |
| — | IMMUNOGEN INC | 21,741,458 | $97.84M | 2.6% | $4.50 | $5.49 | — | COM | 45253H101 |
| NKTX | NKARTA INC | 7,805,129 | $96.16M | 2.6% | $12.32 * | $24.86 | -47.2% | COM | 65487U108 |
| — | BELLUS HEALTH INC NEW | 10,230,274 | $94.53M | 2.5% | $9.24 | $8.05 | — | COM NEW | 07987C204 |
| — | ITEOS THERAPEUTICS INC | 4,417,259 | $91M | 2.4% | $20.60 | $24.67 | — | COM | 46565G104 |
| — | VERU INC | 7,900,000 | $89.27M | 2.4% | $11.30 | $11.30 | — | COM | 92536C103 |
| — | DICE THERAPEUTICS INC | 5,208,911 | $80.84M | 2.2% | $15.52 | $32.75 | — | COM | 23345J104 |
| PEPG | PEPGEN INC | 8,131,952 | $80.75M | 2.2% | $9.93 * | $11.15 | 0.0% | COM | 713317105 |
| — | FORMA THERAPEUTICS HLDGS INC | 9,011,651 | $62.09M | 1.7% | $6.89 | $46.49 | — | SHS | 34633R104 |
| ACRS | ACLARIS THERAPEUTICS INC | 4,398,453 | $61.4M | 1.6% | $13.96 | $13.86 | +1.1% | COM | 00461U105 |
| — | POINT BIOPHARMA GLOBAL INC | 9,003,018 | $61.31M | 1.6% | $6.81 | $7.66 | — | COM | 730541109 |
| CLDX | CELLDEX THERAPEUTICS INC NEW | 2,075,000 | $55.94M | 1.5% | $26.96 * | $44.65 | -35.0% | COM NEW | 15117B202 |
| WVE | WAVE LIFE SCIENCES LTD | 17,202,009 | $55.91M | 1.5% | $3.25 * | $8.85 | -78.3% | SHS | Y95308105 |
| — | VOR BIOPHARMA INC | 11,120,973 | $55.27M | 1.5% | $4.97 | $43.10 | — | COM | 929033108 |
| — | KINNATE BIOPHARMA INC | 4,264,144 | $53.77M | 1.4% | $12.61 | $35.29 | — | COM | 49705R105 |
| TYRA | TYRA BIOSCIENCES INC | 7,236,454 | $51.74M | 1.4% | $7.15 * | $19.11 | -58.3% | COM | 90240B106 |
| GHRS | GH RESEARCH PLC | 4,898,373 | $48.89M | 1.3% | $9.98 * | $19.20 | -32.3% | ORDINARY SHARES | G3855L106 |
| GERN | GERON CORP | 30,126,299 | $46.7M | 1.2% | $1.55 * | $1.49 | -5.5% | COM | 374163103 |
| NTRA | NATERA INC | 1,310,289 | $46.44M | 1.2% | $35.44 * | $60.09 | -38.4% | COM | 632307104 |
| ABOS | ACUMEN PHARMACEUTICALS INC | 9,770,773 | $45.92M | 1.2% | $4.70 * | $16.64 | -77.4% | COM | 00509G209 |
| — | NANOSTRING TECHNOLOGIES | 3,584,478 | $45.52M | 1.2% | $12.70 | $12.70 | — | COM | 63009R109 |
| RXST | RXSIGHT INC | 3,052,796 | $42.98M | 1.1% | $14.08 * | $13.76 | -4.2% | COM | 78349D107 |
| ENTA | ENANTA PHARMACEUTICALS INC | 896,724 | $42.39M | 1.1% | $47.27 * | $65.07 | -16.6% | COM | 29251M106 |
| CLYM | ELIEM THERAPEUTICS INC | 13,150,849 | $39.72M | 1.1% | $3.02 * | $20.66 | -77.1% | COM | 28658R106 |
| RLMD | RELMADA THERAPEUTICS INC | 2,000,000 | $37.98M | 1.0% | $18.99 * | $22.24 | -1.9% | COM | 75955J402 |
| — | INSTIL BIO INC | 7,670,793 | $35.44M | 0.9% | $4.62 | $17.61 | — | COM | 45783C101 |
| — | ICOSAVAX INC | 5,963,565 | $34.17M | 0.9% | $5.73 | $28.89 | — | COM | 45114M109 |
| RNAM | AVIDITY BIOSCIENCES INC | 2,167,391 | $31.49M | 0.8% | $14.53 * | $17.92 | -17.0% | COM | 05370A108 |
| DSGN | DESIGN THERAPEUTICS INC | 2,186,636 | $30.61M | 0.8% | $14.00 * | $31.14 | -56.6% | COM | 25056L103 |
| ANTX | AN2 THERAPEUTICS INC | 3,748,389 | $29.05M | 0.8% | $7.75 * | $15.13 | -12.5% | COM | 037326105 |
| RCKT | ROCKET PHARMACEUTICALS INC | 2,107,149 | $28.99M | 0.8% | $13.76 * | $36.45 | -67.3% | COM | 77313F106 |
| EYPT | EYEPOINT PHARMACEUTICALS INC | 3,370,506 | $26.53M | 0.7% | $7.87 * | $11.52 | -12.8% | COM NEW | 30233G209 |
| — | 89BIO INC | 7,782,669 | $25.06M | 0.7% | $3.22 | $17.59 | — | COM | 282559103 |
| — | SATSUMA PHARMACEUTICALS INC | 5,914,252 | $24.48M | 0.7% | $4.14 | $13.11 | — | COM | 80405P107 |
| PMVP | PMV PHARMACEUTICALS INC | 1,710,265 | $24.37M | 0.6% | $14.25 * | $36.80 | -60.5% | COM | 69353Y103 |
| VERA | VERA THERAPEUTICS INC | 1,578,820 | $21.49M | 0.6% | $13.61 * | $21.52 | -18.9% | CL A | 92337R101 |
| — | VERONA PHARMA PLC | 5,100,000 | $21.37M | 0.6% | $4.19 | $6.24 | — | SPONSORED ADS | 925050106 |
| RYTM | RHYTHM PHARMACEUTICALS INC | 4,871,067 | $20.21M | 0.5% | $4.15 * | $24.79 | -77.9% | COM | 76243J105 |
| TNYA | TENAYA THERAPEUTICS INC | 3,551,508 | $20M | 0.5% | $5.63 * | $21.49 | -62.3% | COM | 87990A106 |
| DYN | DYNE THERAPEUTICS INC | 2,805,045 | $19.27M | 0.5% | $6.87 | $21.96 | -68.6% | COM | 26818M108 |
| — | HILLEVAX INC | 1,760,019 | $19.24M | 0.5% | $10.93 | $10.93 | — | COM | 43157M102 |
| GH | GUARDANT HEALTH INC | 476,380 | $19.22M | 0.5% | $40.34 * | $68.43 | -27.6% | COM | 40131M109 |
| — | PARDES BIOSCIENCES INC | 6,175,038 | $18.96M | 0.5% | $3.07 | $11.85 | — | COM | 69945Q105 |
| HOWL | WEREWOLF THERAPEUTICS INC | 4,291,881 | $17.55M | 0.5% | $4.09 * | $13.70 | -66.7% | COM | 95075A107 |
| — | DA32 LIFE SCNCE | 1,500,000 | $14.54M | 0.4% | $9.69 | $9.83 | — | CLASS A COM | 23312M106 |
| — | CONCERT PHARMACEUTICALS INC | 3,307,203 | $13.92M | 0.4% | $4.21 | $7.05 | — | COM | 206022105 |
| MIST | MILESTONE PHARMACEUTICALS IN | 2,246,503 | $13.82M | 0.4% | $6.15 | $7.17 | -14.3% | COM | 59935V107 |
| — | ACHILLES THERAPEUTICS PLC | 5,014,687 | $12.64M | 0.3% | $2.52 | $11.66 | — | SPONSORED ADS | 00449L102 |
| — | BCLS ACQUISITION CORP | 1,250,000 | $12.38M | 0.3% | $9.90 | $11.14 | — | COM CL A | G0904B105 |
| — | OTONOMY INC | 5,600,000 | $11.65M | 0.3% | $2.08 | $2.03 | — | COM | 68906L105 |
| LIANY | LIANBIO | 4,622,574 | $9.985M | 0.3% | $2.16 | $6.16 | — | SPONSORED ADS | 53000N108 |
| — | FRAZIER LIFESCIENCES ACQU CO | 1,000,000 | $9.87M | 0.3% | $9.87 | $10.38 | — | CL A SHS | G3710A121 |
| — | ARYA SCIENCES ACQUISITN | 1,000,000 | $9.72M | 0.3% | $9.72 | $9.88 | — | CLASS A ORD SHS | G31658100 |
| RLAY | RELAY THERAPEUTICS INC | 549,055 | $9.197M | 0.2% | $16.75 * | $31.60 | -32.2% | COM | 75943R102 |
| IOBT | IO BIOTECH INC | 1,857,755 | $8.676M | 0.2% | $4.67 * | $9.66 | -36.6% | COM | 449778109 |
| — | SOLID BIOSCIENCES INC | 12,367,873 | $7.614M | 0.2% | $0.62 | $7.59 | — | COM | 83422E105 |
| — | 5 01 ACQUISITION CORP | 750,000 | $7.425M | 0.2% | $9.90 | $10.17 | — | COM CL A | 33836P105 |
| — | SYNLOGIC INC | 5,825,858 | $6.7M | 0.2% | $1.15 | $3.05 | — | COM | 87166L100 |
| BDTX | BLACK DIAMOND THERAPEUTICS I | 2,589,904 | $6.371M | 0.2% | $2.46 * | $30.22 | -92.3% | COM | 09203E105 |
| IPSC | CENTURY THERAPEUTICS INC | 756,821 | $6.357M | 0.2% | $8.40 * | $25.37 | -61.3% | COM | 15673T100 |
| — | HEALTH SCIENCES ACQ CORP 2 | 625,000 | $6.225M | 0.2% | $9.96 | $11.00 | — | ORD SHS | G4411D109 |
| — | CONNECT BIOPHARMA HLDGS LTD | 6,991,003 | $6.082M | 0.2% | $0.87 | $19.09 | — | ADS | 207523101 |
| BMEA | BIOMEA FUSION INC | 500,000 | $5.99M | 0.2% | $11.98 * | $17.65 | -66.8% | COM | 09077A106 |
| — | ATHIRA PHARMA INC | 1,878,000 | $5.728M | 0.2% | $3.05 | $3.05 | — | COM | 04746L104 |
| XLO | XILIO THERAPEUTICS INC | 1,649,711 | $4.817M | 0.1% | $2.92 * | $17.03 | -77.8% | COM | 98422T100 |
| WHWK | AADI BIOSCIENCE INC | 383,028 | $4.719M | 0.1% | $12.32 * | $14.85 | 0.0% | COM | 00032Q104 |
| LAB | STANDARD BIOTOOLS INC | 1,987,589 | $3.18M | 0.1% | $1.60 * | $2.47 | 0.0% | COM | 34385P108 |
| ENTX | ENTERA BIO LTD | 2,353,000 | $3.129M | 0.1% | $1.33 * | $3.70 | -39.9% | SHS | M40527109 |
| TERN | TERNS PHARMACEUTICALS INC | 1,261,435 | $3.128M | 0.1% | $2.48 * | $2.00 | 0.0% | COM | 880881107 |
| BCAB | BIOATLA INC | 1,031,805 | $2.941M | 0.1% | $2.85 * | $3.18 | 0.0% | COM | 09077B104 |
| — | ASTRIA THERAPEUTICS INC | 760,857 | $2.283M | 0.1% | $3.00 | $8.84 | — | COM | 04635X102 |
| PYXS | PYXIS ONCOLOGY INC | 953,393 | $2.269M | 0.1% | $2.38 * | $11.45 | -76.7% | COMMON STOCK | 747324101 |
| — | ADVERUM BIOTECHNOLOGIES INC | 1,726,019 | $2.071M | 0.1% | $1.20 | $1.20 | — | COM | 00773U108 |
| LRMR | LARIMAR THERAPEUTICS INC | 1,031,482 | $2.022M | 0.1% | $1.96 * | $11.65 | -74.6% | COM | 517125100 |
| — | ORCHARD THERAPEUTICS PLC | 3,040,885 | $1.776M | 0.0% | $0.58 | $10.43 | — | ADS | 68570P101 |
| CVRX | CVRX INC | 275,000 | $1.653M | 0.0% | $6.01 * | $28.00 | -79.5% | COM | 126638105 |
| — | SENSEI BIOTHERAPEUTICS | 723,549 | $1.642M | 0.0% | $2.27 | $2.27 | — | COM | 81728A108 |
| OLMA | OLEMA PHARMACEUTICALS INC | 233,793 | $952K | 0.0% | $4.07 * | $46.89 | -93.2% | COM | 68062P106 |
| — | BOLT BIOTHERAPEUTICS INC | 450,141 | $918K | 0.0% | $2.04 | $2.04 | — | COM | 097702104 |
| — | AVROBIO INC | 559,600 | $515K | 0.0% | $0.92 | $0.92 | — | COM | 05455M100 |
| — | CALADRIUS BIOSCIENCES | 752,500 | $399K | 0.0% | $0.53 | $0.53 | — | COM | 128058203 |