Location: New York, NY
CIK: 0001263508 · Show all filings
Period: Q3 2014 (← Previous) (Next →)
Filing Date: Nov 14, 2014
Total Value: $7.941B (75.2% shares, 24.8% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| — | Pharmacyclics Inc. | 9,656,599 | $1.134B | 14.3% | $80.38 | — | COM | 716933106 |
| — | Seattle Genetics, Inc. | 22,475,729 | $836M | 10.5% | $32.51 | — | COM | 812578102 |
| — | Salix 2.75% 5/15/15 | 219,440,000 | $737M | 9.3% | $1.52 | — | CONV BONDS | 795435AC0 |
| — | Synageva Biopharma Corp. | 10,660,432 | $733M | 9.2% | $45.53 | — | COM | 87159A103 |
| INCY | Incyte Corp. | 14,845,559 | $728M | 9.2% | $21.85 | +129.5% | COM | 45337C102 |
| ACAD | Acadia Pharmaceuticals Inc. | 20,481,442 | $507M | 6.4% | $14.07 | +66.2% | COM | 004225108 |
| — | Genomic Health Inc. | 13,655,618 | $387M | 4.9% | $31.71 | — | COM | 37244C101 |
| — | Incyte Corporation Notes 1.25% 11/15/2020 | 274,500,000 | $334M | 4.2% | $1.21 | — | CONV BONDS | 45337CAL6 |
| — | Incyte Corporation Notes 0.375% 11/15/2018 | 259,000,000 | $308M | 3.9% | $1.20 | — | CONV BONDS | 45337CAK8 |
| — | Avanir Pharmaceuticals | 20,974,677 | $250M | 3.1% | $5.99 | — | COM | 05348P401 |
| — | Incyte Corporation Notes 4.75% 10/1/2015 | 40,446,000 | $225M | 2.8% | $6.08 | — | CONV BONDS | 45337CAJ1 |
| BMRN | Biomarin Pharmaceuticals | 2,370,464 | $171M | 2.2% | $65.60 | +0.2% | COM | 09061G101 |
| — | Avanir Pharmaceuticals Inc C @ 1.0 OCT 14 | 9,356,200 | $112M | 1.4% | $5.99 | — | Call | 05348P401 |
| BCRX | Biocryst Pharmaceuticals Inc. | 10,713,686 | $105M | 1.3% | $5.72 | +114.1% | COM | 09058V103 |
| — | Anacor Pharmaceuticals | 4,204,702 | $103M | 1.3% | $19.02 | — | COM | 032420101 |
| — | Gilead 1.625% 5/1/16 | 21,500,000 | $100M | 1.3% | $2.26 | — | CONV BONDS | 375558AP8 |
| — | Xoma Corp. | 23,071,472 | $97.13M | 1.2% | $3.73 | — | COM | 98419J107 |
| — | Biomarin Pharmaceuticals Notes 1.875% 4/23/2017 | 22,898,000 | $81.36M | 1.0% | $2.76 | — | CONV BONDS | 09061GAD3 |
| — | Medivation 2.625% 4/1/17 | 34,720,000 | $67.75M | 0.9% | $1.27 | — | CONV BONDS | 58501NAA9 |
| — | Dyax Corp. | 6,157,789 | $62.32M | 0.8% | $8.91 | — | COM | 26746E103 |
| — | Acorda Therapeutics Notes 1.75% 6/15/2021 | 60,000,000 | $62.05M | 0.8% | $1.03 | — | CONV BONDS | 00484MAA4 |
| CERS | Cerus | 11,940,178 | $47.88M | 0.6% | $4.62 | -16.7% | COM | 157085101 |
| VNDA | Vanda Pharmaceuticals, Inc. | 4,372,153 | $45.38M | 0.6% | $7.41 | +76.8% | COM | 921659108 |
| — | Mirati Therapeutics Inc. | 2,380,074 | $41.67M | 0.5% | $15.40 | — | COM | 60468T105 |
| — | Xenoport | 6,815,777 | $36.67M | 0.5% | $5.22 | — | COM | 98411C100 |
| — | Salix 1.5% 3/15/19 | 15,000,000 | $36.24M | 0.5% | $1.49 | — | CONV BONDS | 795435AE6 |
| — | Derma Sciences | 3,537,137 | $29.46M | 0.4% | $12.84 | — | COM | 249827502 |
| — | Repros Therapeutics | 2,778,654 | $27.51M | 0.3% | $18.45 | — | COM | 76028H209 |
| GILD | Gilead Sciences Inc. | 256,108 | $27.26M | 0.3% | $36.21 | +87.9% | COM | 375558103 |
| — | Acorda Therapeutics, Inc. | 753,391 | $25.52M | 0.3% | $37.91 | — | COM | 00484M106 |
| HALO | Halozyme Therapeutics Inc. | 2,776,143 | $25.26M | 0.3% | $6.50 | +46.6% | COM | 40637H109 |
| — | Versartis Inc. | 1,246,089 | $23.66M | 0.3% | $28.04 | — | COM | 92529L102 |
| — | Progenics Pharmaceuticals, Inc. | 4,449,797 | $23.09M | 0.3% | $4.44 | — | COM | 743187106 |
| CPRX | Catalyst Pharmaceuticals, Inc. | 6,715,462 | $22.3M | 0.3% | $2.45 | +6.6% | COM | 14888U101 |
| TGTX | TG Therapeutics | 2,050,313 | $21.88M | 0.3% | $4.61 | +101.3% | COM | 88322Q108 |
| HRTX | Heron Therapeutics, Inc. | 2,607,784 | $21.72M | 0.3% | $12.49 | -25.5% | COM | 427746102 |
| — | Mallinckrodt PUB LTD CO | 201,856 | $18.2M | 0.2% | $90.15 | — | COM | G5785G107 |
| — | Arrowhead Research Corp. | 1,230,802 | $18.18M | 0.2% | $9.90 | — | COM | 042797209 |
| — | Ambit Biosciences Corp. | 1,093,332 | $16.84M | 0.2% | $9.65 | — | COM | 02318X100 |
| INSM | Insmed Inc. | 1,107,850 | $14.46M | 0.2% | $13.86 | +8.8% | COM | 457669307 |
| — | Biomarin Pharmaceuticals Notes 0.75% 10/15/2018 | 12,500,000 | $13.2M | 0.2% | $1.06 | — | CONV BONDS | 09061GAE1 |
| AGIO | Agios Pharmaceuticals | 169,893 | $10.42M | 0.1% | $27.47 | +56.9% | COM | 00847X104 |
| OMER | Omeros Corp. | 808,775 | $10.29M | 0.1% | $7.65 | +83.1% | COM | 682143102 |
| — | Tekmire Pharmaceuticals Corp. | 484,156 | $10.23M | 0.1% | $7.97 | — | COM | 87911B209 |
| — | Kythera Biopharmaceuticals | 311,255 | $10.2M | 0.1% | $34.55 | — | COM | 501570105 |
| SGMO | Sangamo Biosceiences, Inc. | 864,856 | $9.327M | 0.1% | $12.69 | +3.0% | COM | 800677106 |
| NBIX | Neurocrine Biosciences, Inc. | 554,590 | $8.69M | 0.1% | $16.53 | -9.6% | COM | 64125C109 |
| RARE | Ultragenyx Pharmaceuticals | 150,000 | $8.49M | 0.1% | $51.09 | -1.5% | COM | 90400D108 |
| — | Aquinox Pharmaceuticals, Inc. | 1,211,851 | $8.071M | 0.1% | $12.73 | — | COM | 03842B101 |
| — | Threshold Pharma | 2,158,141 | $7.791M | 0.1% | $4.49 | — | COM | 885807206 |
| — | QLT Inc. | 1,535,863 | $6.942M | 0.1% | $4.39 | — | COM | 746927102 |
| PRQR | ProQR Therapeutics NV | 400,000 | $6.876M | 0.1% | $16.02 | 0.0% | COM | N71542109 |
| — | Discovery Laboratories Inc. | 3,652,117 | $6.72M | 0.1% | $1.95 | — | COM | 254668403 |
| MGNX | Macrogenics, Inc. | 311,891 | $6.519M | 0.1% | $22.61 | -8.5% | COM | 556099109 |
| — | Osiris Therapeutics Inc. | 510,606 | $6.429M | 0.1% | $16.34 | — | COM | 68827R108 |
| — | Aerie Pharmaceuticals | 299,356 | $6.194M | 0.1% | $17.96 | — | COM | 00771V108 |
| — | Epizyme Inc. | 214,012 | $5.802M | 0.1% | $21.47 | — | COM | 29428V104 |
| — | Concert Pharmaceuticals, Inc. | 451,496 | $5.693M | 0.1% | $10.39 | — | COM | 206022105 |
| — | Foamix Pharmaceuticals Ltd. | 1,021,600 | $5.568M | 0.1% | $5.45 | — | COM | M46135105 |
| — | Bluebird Bio Inc. | 150,000 | $5.382M | 0.1% | $25.09 | — | COM | 09609G100 |
| — | Array Biopharma Inc. | 1,433,797 | $5.119M | 0.1% | $4.54 | — | COM | 04269X105 |
| — | Novavax Inc. | 1,223,362 | $5.101M | 0.1% | $3.15 | — | COM | 670002104 |
| XNCR | Xencor | 542,363 | $5.049M | 0.1% | $8.58 | +18.0% | COM | 98401F105 |
| — | Ignyta | 571,000 | $4.602M | 0.1% | $8.30 | — | COM | 451731103 |
| IRWD | Ironwood Pharmaceuticals | 346,160 | $4.485M | 0.1% | $11.63 | -1.6% | COM | 46333X108 |
| — | Achillion | 438,337 | $4.375M | 0.1% | $8.18 | — | COM | 00448Q201 |
| — | Stemline Therapeutics Inc. | 338,671 | $4.22M | 0.1% | $23.84 | — | COM | 85858C107 |
| INFIQ | Infinity Pharmaceuticals Inc. | 312,025 | $4.187M | 0.1% | $13.42 | -11.3% | COM | 45665G303 |
| — | Celsus Therapeutics | 673,887 | $4.111M | 0.1% | $6.49 | — | SPONSORED ADR NE | 15119A202 |
| — | La Jolla Pharmaceuticals, Inc. | 421,631 | $4.052M | 0.1% | $10.24 | — | COM | 503459604 |
| — | Celladon Corp | 375,000 | $3.923M | 0.0% | $10.46 | — | COM | 15117E107 |
| — | Isis Pharmaceuticals, Inc. | 96,303 | $3.739M | 0.0% | $26.87 | — | COM | 464330109 |
| — | Idera Pharmaceuticals Inc. | 1,619,258 | $3.708M | 0.0% | $0.91 | — | COM | 45168K306 |
| — | BioDelivery Sciences Intl. Inc. | 210,021 | $3.589M | 0.0% | $4.06 | — | COM | 09060J106 |
| LGND | Ligand Pharmaceuticals | 73,400 | $3.449M | 0.0% | $41.68 | -20.4% | COM | 53220K504 |
| — | Cytrx Corp. | 1,350,000 | $3.429M | 0.0% | $3.49 | — | COM | 232828509 |
| — | Karyopharm Therapeutics | 94,095 | $3.288M | 0.0% | $31.71 | — | COM | 48576U106 |
| — | Lipocine Inc. | 500,000 | $3.055M | 0.0% | $6.10 | — | COM | 53630X104 |
| ENTA | Enanta Pharmaceuticals | 75,357 | $2.982M | 0.0% | $19.50 | +104.4% | COM | 29251M106 |
| FOLD | Amicus Therapeutics | 481,697 | $2.866M | 0.0% | $3.07 | +70.5% | COM | 03152W109 |
| — | Biota Pharmaceuticals | 1,106,910 | $2.734M | 0.0% | $4.19 | — | COM | 090694100 |
| — | Synergy Pharmaceuticals | 973,245 | $2.71M | 0.0% | $4.32 | — | COM | 871639308 |
| — | Zogenix, Inc. | 2,350,400 | $2.703M | 0.0% | $2.18 | — | COM | 98978L105 |
| — | Affimed Therapeutics B.V. | 400,000 | $2.52M | 0.0% | $6.30 | — | COM | N01045108 |
| — | Sage Therapeutics Inc. | 75,000 | $2.363M | 0.0% | $31.51 | — | COM | 78667J108 |
| AUPH | Aurinia Pharmaceuticals, Inc. | 727,669 | $2.339M | 0.0% | $3.55 | 0.0% | COM | 05156V102 |
| — | Alder Biopharmaceutical Inc. | 153,350 | $1.944M | 0.0% | $20.07 | — | COM | 014339105 |
| OSUR | Orasure Technologies Inc. | 234,664 | $1.694M | 0.0% | $4.46 | +79.4% | COM | 68554V108 |
| — | Mast Therapeutics, Inc. | 3,000,000 | $1.671M | 0.0% | $0.56 | — | COM | 576314108 |
| — | Synta Pharmaceuticals | 500,000 | $1.505M | 0.0% | $4.99 | — | COM | 87162T206 |
| — | Receptos Inc. | 23,900 | $1.484M | 0.0% | $19.89 | — | COM | 756207106 |
| — | Foundation Medicine Inc. | 78,162 | $1.482M | 0.0% | $26.96 | — | COM | 350465100 |
| — | Ophthotech Corp. | 36,776 | $1.432M | 0.0% | $32.35 | — | COM | 683745103 |
| — | Mediwound Ltd. | 225,000 | $1.418M | 0.0% | $11.38 | — | COM | M68830104 |
| — | Salix Pharmaceuticals | 8,621 | $1.347M | 0.0% | $99.30 | — | COM | 795435106 |
| — | Marinus Pharmaceuticals Inc. | 204,476 | $1.323M | 0.0% | $6.47 | — | COM | 56854Q101 |
| — | Loxo Oncology Inc. | 100,000 | $1.313M | 0.0% | $13.13 | — | COM | 548862101 |
| — | Rigel Pharmaceuticals | 481,972 | $935K | 0.0% | $3.58 | — | COM | 766559603 |
| ALNY | Alnylam Pharmaceuticals, Inc. | 11,600 | $906K | 0.0% | $77.42 | -16.7% | COM | 02043Q107 |
| — | Achaogen Inc. | 100,000 | $896K | 0.0% | $15.46 | — | COM | 004449104 |
| — | Acceleron Pharma Inc. | 28,765 | $870K | 0.0% | $39.60 | — | COM | 00434H108 |
| — | Tesaro Inc. | 31,218 | $840K | 0.0% | $32.74 | — | COM | 881569107 |
| GERN | Geron Corp. | 402,629 | $805K | 0.0% | $1.08 | +127.2% | COM | 374163103 |
| — | Ziopharm Oncology Inc. | 244,619 | $646K | 0.0% | $2.11 | — | COM | 98973P101 |
| QURE | Uniquere B.V. | 30,672 | $284K | 0.0% | $15.95 | -31.2% | COM | N90064101 |
| — | Five Prime Therapeutics Inc. | 19,823 | $233K | 0.0% | $16.80 | — | COM | 33830X104 |
| — | Chemocentryx Inc. | 50,000 | $225K | 0.0% | $14.14 | — | COM | 16383L106 |
| — | Cyclacel Pharmaceuticals Pfd. Conv. Ex 6% | 13,253 | $103K | 0.0% | $7.20 | — | PFD CONV EX 6% | 23254L207 |