Location: New York, NY
CIK: 0001493215 · Show all filings
Period: Q4 2021 (← Previous) (Next →)
Filing Date: Feb 14, 2022
Total Value: $6.848B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| SPY | SPDR S&P 500 ETF TR | 889,739 | $423M | 6.2% | $399.35 | — | TR UNIT | 78462F103 |
| RCKT | ROCKET PHARMACEUTICALS INC | 15,802,802 | $345M | 5.0% | $17.68 | +54.3% | COM | 77313F106 |
| ALNY | ALNYLAM PHARMACEUTICALS INC | 1,975,879 | $335M | 4.9% | $95.85 | +93.9% | COM | 02043Q107 |
| TMO | THERMO FISHER SCIENTIFIC INC | 435,500 | $291M | 4.2% | $545.71 | +13.1% | COM | 883556102 |
| MASI | MASIMO CORP | 849,971 | $249M | 3.6% | $171.03 | +66.5% | COM | 574795100 |
| — | MIRATI THERAPEUTICS INC | 1,561,497 | $229M | 3.3% | $108.92 | — | COM | 60468T105 |
| PTCT | PTC THERAPEUTICS INC | 5,293,966 | $211M | 3.1% | $34.80 | +10.0% | COM | 69366J200 |
| ILMN | ILLUMINA INC | 490,399 | $187M | 2.7% | $350.77 | +8.0% | COM | 452327109 |
| PEN | PENUMBRA INC | 620,871 | $178M | 2.6% | $267.12 | -1.0% | COM | 70975L107 |
| VCEL | VERICEL CORP | 4,517,570 | $178M | 2.6% | $12.98 | +237.8% | COM | 92346J108 |
| TNDM | TANDEM DIABETES CARE INC | 1,160,734 | $175M | 2.6% | $82.98 | +62.7% | COM NEW | 875372203 |
| NTRA | NATERA INC | 1,862,234 | $174M | 2.5% | $42.82 | +142.4% | COM | 632307104 |
| ESTA | ESTABLISHMENT LABS HLDGS INC | 2,319,138 | $157M | 2.3% | $24.65 | +183.5% | COM | G31249108 |
| CLDX | CELLDEX THERAPEUTICS INC NEW | 3,921,579 | $152M | 2.2% | $8.74 | +398.8% | COM NEW | 15117B202 |
| — | PROMETHEUS BIOSCIENCES INC | 3,264,031 | $129M | 1.9% | $15.85 | — | COM | 74349U108 |
| GMED | GLOBUS MED INC | 1,670,811 | $121M | 1.8% | $57.59 | +26.0% | CL A | 379577208 |
| CYTK | CYTOKINETICS INC | 2,561,182 | $117M | 1.7% | $26.72 | +44.4% | COM NEW | 23282W605 |
| RARE | ULTRAGENYX PHARMACEUTICAL IN | 1,373,284 | $115M | 1.7% | $81.37 | 0.0% | COM | 90400D108 |
| RNAM | AVIDITY BIOSCIENCES INC | 4,795,000 | $114M | 1.7% | $27.65 | -13.6% | COM | 05370A108 |
| — | IVERIC BIO INC | 6,722,624 | $112M | 1.6% | $5.11 | — | COM | 46583P102 |
| ARGX | ARGENX SE | 317,447 | $111M | 1.6% | $302.46 | — | SPONSORED ADR | 04016X101 |
| — | ITEOS THERAPEUTICS INC | 2,353,015 | $110M | 1.6% | $29.58 | — | COM | 46565G104 |
| TXG | 10X GENOMICS INC | 734,481 | $109M | 1.6% | $88.44 | +73.2% | CL A COM | 88025U109 |
| — | AXONICS INC | 1,943,864 | $109M | 1.6% | $21.35 | — | COM | 05465P101 |
| APLS | APELLIS PHARMACEUTICALS INC | 1,990,404 | $94.11M | 1.4% | $39.37 | 0.0% | COM | 03753U106 |
| PTGX | PROTAGONIST THERAPEUTICS INC | 2,599,822 | $88.91M | 1.3% | $18.14 | +74.2% | COM | 74366E102 |
| STOK | STOKE THERAPEUTICS INC | 3,644,248 | $87.43M | 1.3% | $27.59 | -13.5% | COM | 86150R107 |
| GH | GUARDANT HEALTH INC | 813,342 | $81.35M | 1.2% | $110.63 | -6.5% | COM | 40131M109 |
| CCCC | C4 THERAPEUTICS INC | 2,494,965 | $80.34M | 1.2% | $30.91 | +27.9% | COM STK | 12529R107 |
| PMVP | PMV PHARMACEUTICALS INC | 2,980,960 | $68.86M | 1.0% | $27.06 | -10.7% | COM | 69353Y103 |
| FULC | FULCRUM THERAPEUTICS INC | 3,866,872 | $68.41M | 1.0% | $13.13 | +50.9% | COM | 359616109 |
| MGNX | MACROGENICS INC | 3,975,554 | $63.81M | 0.9% | $22.70 | -17.1% | COM | 556099109 |
| AXSM | AXSOME THERAPEUTICS INC | 1,618,819 | $61.16M | 0.9% | $40.14 | -8.3% | COM | 05464T104 |
| RGNX | REGENXBIO INC | 1,845,366 | $60.34M | 0.9% | $34.74 | -2.0% | COM | 75901B107 |
| IDYA | IDEAYA BIOSCIENCES INC | 2,520,076 | $59.58M | 0.9% | $16.35 | +42.1% | COM | 45166A102 |
| — | CUTERA INC | 1,397,063 | $57.73M | 0.8% | $47.33 | — | COM | 232109108 |
| PRQR | PROQR THRAPEUTICS N V | 7,027,725 | $56.29M | 0.8% | $10.69 | -28.8% | SHS EURO | N71542109 |
| BCYC | BICYCLE THERAPEUTICS PLC | 869,271 | $52.91M | 0.8% | $60.87 | — | SPONSORED ADS | 088786108 |
| — | ADICET BIO INC | 3,023,744 | $52.88M | 0.8% | $17.49 | — | COM | 007002108 |
| SRPT | SAREPTA THERAPEUTICS INC | 582,265 | $52.43M | 0.8% | $85.49 | 0.0% | COM | 803607100 |
| GHRS | GH RESEARCH PLC | 2,168,957 | $50.6M | 0.7% | $20.43 | +7.6% | ORDINARY SHARES | G3855L106 |
| — | SCIENCE 37 HOLDINGS INC | 3,975,000 | $49.57M | 0.7% | $12.47 | — | COM | 808644108 |
| DMTKQ | DERMTECH INC | 3,118,666 | $49.27M | 0.7% | $9.75 | — | COM | 24984K105 |
| RLMD | RELMADA THERAPEUTICS INC | 2,186,324 | $49.26M | 0.7% | $31.64 | -29.7% | COM | 75955J402 |
| — | BELLUS HEALTH INC NEW | 5,968,017 | $48.04M | 0.7% | $6.71 | — | COM NEW | 07987C204 |
| TNYA | TENAYA THERAPEUTICS INC | 2,458,750 | $46.59M | 0.7% | $21.49 | +1.4% | COM | 87990A106 |
| — | AVADEL PHARMACEUTICALS PLC | 5,741,939 | $46.4M | 0.7% | $7.74 | — | SPONSORED ADR | 05337M104 |
| TARS | TARSUS PHARMACEUTICALS INC | 2,013,601 | $45.31M | 0.7% | $28.48 | -8.7% | COM | 87650L103 |
| APYX | APYX MEDICAL CORPORATION | 3,398,279 | $43.57M | 0.6% | $7.55 | +85.4% | COM | 03837C106 |
| IMCR | IMMUNOCORE HLDGS PLC | 1,245,532 | $42.65M | 0.6% | $40.26 | — | ADS | 45258D105 |
| — | OUTSET MED INC | 894,652 | $41.23M | 0.6% | $51.78 | — | COM | 690145107 |
| — | OYSTER PT PHARMA INC | 2,058,504 | $37.59M | 0.5% | $30.67 | — | COM | 69242L106 |
| — | ESSA PHARMA INC | 2,637,192 | $37.45M | 0.5% | $28.61 | — | COM NEW | 29668H708 |
| LUNG | PULMONX CORP | 1,164,600 | $37.35M | 0.5% | $48.68 | -25.0% | COM | 745848101 |
| VTYX | VENTYX BIOSCIENCES INC | 1,551,778 | $30.82M | 0.5% | $18.95 | 0.0% | COM | 92332V107 |
| QTRX | QUANTERIX CORP | 686,470 | $29.11M | 0.4% | $46.70 | 0.0% | COM | 74766Q101 |
| MIST | MILESTONE PHARMACEUTICALS IN | 4,315,102 | $28.26M | 0.4% | $20.06 | -70.1% | COM | 59935V107 |
| CTMX | CYTOMX THERAPEUTICS INC | 6,029,700 | $26.11M | 0.4% | $7.45 | -21.4% | COM | 23284F105 |
| CSTL | CASTLE BIOSCIENCES INC | 599,009 | $25.68M | 0.4% | $26.48 | +97.4% | COM | 14843C105 |
| — | NANOSTRING TECHNOLOGIES INC | 604,029 | $25.51M | 0.4% | $26.11 | — | COM | 63009R109 |
| — | ATHIRA PHARMA INC | 1,906,557 | $24.84M | 0.4% | $17.00 | — | COM | 04746L104 |
| GLUE | MONTE ROSA THERAPEUTICS INC | 1,214,572 | $24.8M | 0.4% | $20.37 | +2.8% | COM | 61225M102 |
| — | JOUNCE THERAPEUTICS INC | 2,863,198 | $23.91M | 0.3% | $7.90 | — | COM | 481116101 |
| PYXS | PYXIS ONCOLOGY INC | 2,120,760 | $23.27M | 0.3% | $11.45 | 0.0% | COMMON STOCK | 747324101 |
| ARWR | ARROWHEAD PHARMACEUTICALS IN | 346,842 | $23M | 0.3% | $68.71 | 0.0% | COM | 04280A100 |
| — | CEREVEL THERAPEUTICS HLDNG I | 666,666 | $21.61M | 0.3% | $19.81 | — | COM | 15678U128 |
| JNJ | JOHNSON & JOHNSON | 125,127 | $21.41M | 0.3% | $119.09 | +21.8% | COM | 478160104 |
| SGHT | SIGHT SCIENCES INC | 1,183,871 | $20.8M | 0.3% | $32.87 | -33.3% | COM | 82657M105 |
| — | LANDOS BIOPHARMA INC | 4,275,722 | $20.52M | 0.3% | $8.96 | — | COM | 515069102 |
| — | RENOVACOR INC | 2,647,540 | $20.39M | 0.3% | $8.61 | — | COM | 75989E106 |
| — | AGENUS INC | 5,868,315 | $18.9M | 0.3% | $4.50 | — | COM NEW | 00847G705 |
| — | OLINK HLDG AB | 1,018,188 | $18.53M | 0.3% | $34.10 | — | SPONSORED ADS | 680710100 |
| WHWK | AADI BIOSCIENCES INC | 764,701 | $18.47M | 0.3% | $30.48 | -17.6% | COM | 00032Q104 |
| TELA | TELA BIO INC | 1,399,686 | $17.92M | 0.3% | $12.40 | +2.2% | COM | 872381108 |
| IMUX | IMMUNIC INC | 1,715,470 | $16.42M | 0.2% | $13.18 | -31.7% | COM | 4525EP101 |
| — | ADVERUM BIOTECHNOLOGIES INC | 7,554,817 | $13.3M | 0.2% | $4.52 | — | COM | 00773U108 |
| BWAY | BRAINSWAY LTD | 1,602,381 | $12.34M | 0.2% | $9.54 | — | SPONSORED ADS | 10501L106 |
| — | LA JOLLA PHARMACEUTICAL CO | 2,327,903 | $10.82M | 0.2% | $10.40 | — | COM PAR $.0001 2 | 503459604 |
| NEO | NEOGENOMICS INC | 311,111 | $10.62M | 0.2% | $44.31 | -11.6% | COM NEW | 64049M209 |
| — | CLEARSIDE BIOMEDICAL INC | 3,806,018 | $10.47M | 0.2% | $0.77 | — | COM | 185063104 |
| OSUR | ORASURE TECHNOLOGIES INC | 1,154,380 | $10.03M | 0.1% | $10.98 | -10.0% | COM | 68554V108 |
| ABUS | ARBUTUS BIOPHARMA CORP | 2,504,493 | $9.742M | 0.1% | $3.30 | +17.6% | COM | 03879J100 |
| XGN | EXAGEN INC | 821,414 | $9.553M | 0.1% | $17.90 | -34.6% | COM | 30068X103 |
| — | GENETRON HLDGS LTD | 1,421,894 | $8.674M | 0.1% | $21.46 | — | ADS | 37186H100 |
| URGN | UROGEN PHARMA LTD | 857,464 | $8.154M | 0.1% | $15.85 | -11.0% | COM | M96088105 |
| ROIV | ROIVANT SCIENCES LTD | 802,717 | $8.091M | 0.1% | $8.32 | 0.0% | SHS | G76279101 |
| NYXH | NYXOAH S A | 344,911 | $7.933M | 0.1% | $31.50 | -27.1% | SHS | B6S7WD106 |
| — | VINCERX PHARMA INC | 741,236 | $7.553M | 0.1% | $18.27 | — | COM NEW | 92731L106 |
| — | MERUS N V | 196,231 | $6.24M | 0.1% | $31.80 | — | COM | N5749R100 |
| — | RESEARCH ALLIANCE CORP II | 637,000 | $6.192M | 0.1% | $10.25 | — | COM CL A | 760873109 |
| — | BCLS ACQUISITION CORP | 612,500 | $6.003M | 0.1% | $11.14 | — | COM CL A | G0904B105 |
| NAUT | NAUTILUS BIOTECHNOLOGY INC | 1,100,000 | $5.698M | 0.1% | $10.83 | -50.6% | COM | 63909J108 |
| — | SUMMIT HEALTHCRE ACQUISTN CO | 500,000 | $4.975M | 0.1% | $10.01 | — | UNIT 06/03/2026 | G8566R128 |
| — | ARYA SCIENCES ACQU CORP IV | 500,000 | $4.958M | 0.1% | $10.47 | — | CL A | G31659108 |
| PRCT | PROCEPT BIOROBOTICS CORP | 194,136 | $4.855M | 0.1% | $38.38 | -3.6% | COM | 74276L105 |
| — | ARYA SCIENCES ACQUISITN CORP | 500,000 | $4.85M | 0.1% | $9.88 | — | CLASS A ORD SHS | G31658100 |
| IMTX | IMMATICS N.V | 350,000 | $4.704M | 0.1% | $10.53 | +18.7% | SHS | N44445109 |
| BMEA | BIOMEA FUSION INC | 593,846 | $4.424M | 0.1% | $17.65 | -40.1% | COM | 09077A106 |
| SOPH | SOPHIA GENETICS SA | 300,000 | $4.23M | 0.1% | $17.59 | -16.2% | ORDINARY SHARES | H82027105 |
| — | 5 01 ACQUISITION CORP | 392,000 | $3.861M | 0.1% | $10.17 | — | COM CL A | 33836P105 |
| — | ASLAN PHARMACEUTICALS LTD | 3,250,000 | $3.64M | 0.1% | $3.35 | — | ADS | 04522R101 |
| — | ISOPLEXIS CORP | 365,000 | $3.354M | 0.0% | $9.19 | — | COM | 465005106 |
| — | MEDICUS SCIENCES ACQUISITION | 300,000 | $2.907M | 0.0% | $9.65 | — | CL A SHS | G5960S108 |
| MXCT | MAXCYTE INC | 275,000 | $2.802M | 0.0% | $15.08 | -28.8% | COM | 57777K106 |
| — | POINT BIOPHARMA GLOBAL INC | 490,000 | $2.744M | 0.0% | $7.69 | — | COM | 730541109 |
| — | CONNECT BIOPHARMA HLDGS LTD | 450,000 | $2.318M | 0.0% | $18.50 | — | ADS | 207523101 |
| — | APOLLO ENDOSURGERY INC | 258,064 | $2.175M | 0.0% | $8.43 | — | COM | 03767D108 |
| — | CODEX DNA INC | 200,000 | $2.16M | 0.0% | $22.00 | — | COM | 192003101 |
| TNGX | TANGO THERAPEUTICS INC | 180,819 | $1.978M | 0.0% | $11.99 | +0.3% | COM | 87583X109 |
| — | MINK THERAPEUTICS INC | 416,666 | $1.858M | 0.0% | $4.46 | — | COM | 603693102 |
| MDXG | MIMEDX GROUP INC | 295,748 | $1.786M | 0.0% | $5.08 | +36.6% | COM | 602496101 |
| — | SEMA4 HOLDINGS CORP | 400,000 | $1.784M | 0.0% | $7.34 | — | COM CL A | 81663L101 |
| RXST | RXSIGHT INC | 150,000 | $1.688M | 0.0% | $13.76 | -12.7% | COM | 78349D107 |
| — | AKOYA BIOSCIENCES INC | 100,000 | $1.531M | 0.0% | $19.34 | — | COM | 00974H104 |
| — | MIROMATRIX MED INC | 280,000 | $1.313M | 0.0% | $11.65 | — | COM | 60471P108 |
| RCEL | AVITA MEDICAL INC | 106,667 | $1.278M | 0.0% | $23.25 | -34.4% | COM | 05380C102 |
| — | SINGULAR GENOMICS SYSTEMS IN | 100,000 | $1.156M | 0.0% | $27.48 | — | COM | 82933R100 |
| MASS | 908 DEVICES INC | 40,000 | $1.035M | 0.0% | $58.41 | -49.6% | COM | 65443P102 |
| — | MINERVA SURGICAL INC | 166,000 | $853K | 0.0% | $5.14 | — | COM | 60343F106 |
| — | BOLT BIOTHERAPEUTICS INC | 126,365 | $619K | 0.0% | $32.91 | — | COM | 097702104 |
| — | ZYMERGEN INC | 70,000 | $468K | 0.0% | $40.01 | — | COM | 98985X100 |
| — | RENOVACOR INC | 350,000 | $200K | 0.0% | $0.64 | — | *W EXP 99/99/999 | 75989E114 |
| — | ACHILLES THERAPEUTICS PLC | 12,229 | $61,000 | 0.0% | $4.99 | — | SPONSORED ADS | 00449L102 |
| — | MEDICUS SCIENCES ACQUISITION | 33,331 | $24,000 | 0.0% | $1.02 | — | *W EXP 02/12/202 | G5960S124 |