Opaleye Management Inc. Quant / Systematic

CIK: 0001595855 · Show all filings

Period: Q2 2014 (← Previous) (Next →)

Filing Date: Aug 14, 2014

Total Value ($000): $115,981 (100.0% shares, 0.0% debt)

Holdings (27)

— CHIMERIX INC 14.9%

Value ($000) $17,333 Shares 790,000 Est. Cost $22.55 Unrealized —

— RETROPHIN INC 12.3%

Value ($000) $14,281 Shares 1,216,400 Est. Cost $20.71 Unrealized —

— ARIAD PHARMACEUTICALS INC 9.1%

Value ($000) $10,574 Shares 1,660,000 Est. Cost $7100.00 Unrealized —

— PHARMACYCLICS INC 7.7%

Value ($000) $8,971 Shares 100,000 Est. Cost $108000.00 Unrealized —

— GENMARK DIAGNOSTICS INC 5.8%

Value ($000) $6,765 Shares 500,000 Est. Cost $10.41 Unrealized —

— BIND THERAPEUTICS INC 5.6%

Value ($000) $6,485 Shares 492,000 Est. Cost $4324.41 Unrealized —

— INSPIREMD INC 5.5%

Value ($000) $6,431 Shares 2,180,000 Est. Cost $1354.42 Unrealized —

— CEMPRA INC 4.7%

Value ($000) $5,417 Shares 504,800 Est. Cost $9402.92 Unrealized —

— CLOVIS ONCOLOGY INC 4.6%

Value ($000) $5,369 Shares 130,000 Est. Cost $41.30 Unrealized —

AGIO AGIOS PHARMACEUTICALS INC 4.5%

Value ($000) $5,269 Shares 115,000 Est. Cost $40.76 Unrealized 0.0%

— CARDIOVASCULAR SYS INC DEL 3.6%

Value ($000) $4,207 Shares 135,000 Est. Cost $33000.00 Unrealized —

CPRX CATALYST PHARM PARTNERS INC 3.0%

Value ($000) $3,488 Shares 1,378,584 Est. Cost $2.02 Unrealized +5.6%

— INSYS THERAPEUTICS INC NEW 2.3%

Value ($000) $2,680 Shares 85,800 Est. Cost $31.24 Unrealized —

— TETRAPHASE PHARMACEUTICALS I 2.0%

Value ($000) $2,289 Shares 169,700 Est. Cost $11760.18 Unrealized —

— MAZOR ROBOTICS LTD 1.8%

Value ($000) $2,108 Shares 120,000 Est. Cost $17.57 Unrealized —

RARE ULTRAGENYX PHARMACEUTICAL IN 1.7%

Value ($000) $2,020 Shares 45,000 Est. Cost $41.17 Unrealized 0.0%

— EVOKE PHARMA INC 1.7%

Value ($000) $1,962 Shares 242,500 Est. Cost $8.37 Unrealized —

— RECRO PHARMA INC 1.5%

Value ($000) $1,762 Shares 220,000 Est. Cost $8.01 Unrealized —

— CELGENE CORP 1.5%

Value ($000) $1,716 Shares 660,000 Est. Cost $2800.00 Unrealized —

— KARYOPHARM THERAPEUTICS INC 1.2%

Value ($000) $1,397 Shares 30,000 Est. Cost $46.57 Unrealized —

— BIOLINERX LTD 1.2%

Value ($000) $1,352 Shares 650,000 Est. Cost $1426.15 Unrealized —

CDXS CODEXIS INC 1.0%

Value ($000) $1,197 Shares 820,000 Est. Cost $1.79 Unrealized -11.4%

— CELATOR PHARMACEUTICALS INC 0.9%

Value ($000) $1,073 Shares 338,402 Est. Cost $2840.08 Unrealized —

— KALOBIOS PHARMACEUTICALS INC 0.6%

Value ($000) $730 Shares 320,000 Est. Cost $2145.33 Unrealized —

ALNY ALNYLAM PHARMACEUTICALS INC 0.4%

Value ($000) $455 Shares 7,200 Est. Cost $59.44 Unrealized 0.0%

— KIPS BAY MED INC 0.3%

Value ($000) $355 Shares 772,031 Est. Cost $0.69 Unrealized —

PRTA PROTHENA CORP PLC 0.3%

Value ($000) $295 Shares 13,104 Est. Cost $25.01 Unrealized 0.0%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
—	CHIMERIX INC	790,000	$17,333	14.9%	$22.55	—	COM	16934W106
—	RETROPHIN INC	1,216,400	$14,281	12.3%	$20.71	—	COM	761299106
—	ARIAD PHARMACEUTICALS INC	1,660,000	$10,574	9.1%	$7100.00	—	COM	04033A100
—	PHARMACYCLICS INC	100,000	$8,971	7.7%	$108000.00	—	COM	716933106
—	GENMARK DIAGNOSTICS INC	500,000	$6,765	5.8%	$10.41	—	COM	372309104
—	BIND THERAPEUTICS INC	492,000	$6,485	5.6%	$4324.41	—	COM	05548N107
—	INSPIREMD INC	2,180,000	$6,431	5.5%	$1354.42	—	COM NEW	45779A309
—	CEMPRA INC	504,800	$5,417	4.7%	$9402.92	—	COM	15130J109
—	CLOVIS ONCOLOGY INC	130,000	$5,369	4.6%	$41.30	—	COM	189464100
AGIO	AGIOS PHARMACEUTICALS INC	115,000	$5,269	4.5%	$40.76	0.0%	COM	00847X104
—	CARDIOVASCULAR SYS INC DEL	135,000	$4,207	3.6%	$33000.00	—	COM	141619106
CPRX	CATALYST PHARM PARTNERS INC	1,378,584	$3,488	3.0%	$2.02	+5.6%	COM	14888U101
—	INSYS THERAPEUTICS INC NEW	85,800	$2,680	2.3%	$31.24	—	COM NEW	45824V209
—	TETRAPHASE PHARMACEUTICALS I	169,700	$2,289	2.0%	$11760.18	—	COM	88165N105
—	MAZOR ROBOTICS LTD	120,000	$2,108	1.8%	$17.57	—	COM	57886P103
RARE	ULTRAGENYX PHARMACEUTICAL IN	45,000	$2,020	1.7%	$41.17	0.0%	COM	90400D108
—	EVOKE PHARMA INC	242,500	$1,962	1.7%	$8.37	—	COM	30049G104
—	RECRO PHARMA INC	220,000	$1,762	1.5%	$8.01	—	COM	75629F109
—	CELGENE CORP	660,000	$1,716	1.5%	$2800.00	—	RIGHT 12/31/2030	151020112
—	KARYOPHARM THERAPEUTICS INC	30,000	$1,397	1.2%	$46.57	—	COM	48576U106
—	BIOLINERX LTD	650,000	$1,352	1.2%	$1426.15	—	COM	09071M106
CDXS	CODEXIS INC	820,000	$1,197	1.0%	$1.79	-11.4%	COM	192005106
—	CELATOR PHARMACEUTICALS INC	338,402	$1,073	0.9%	$2840.08	—	COM	15089R102
—	KALOBIOS PHARMACEUTICALS INC	320,000	$730	0.6%	$2145.33	—	COM	48344T100
ALNY	ALNYLAM PHARMACEUTICALS INC	7,200	$455	0.4%	$59.44	0.0%	COM	02043Q107
—	KIPS BAY MED INC	772,031	$355	0.3%	$0.69	—	COM	49726K105
PRTA	PROTHENA CORP PLC	13,104	$295	0.3%	$25.01	0.0%	COM	G72800108