STEMPOINT CAPITAL LP Hedge Fund

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
TWST	TWIST BIOSCIENCE CORP	518,355	$16,442	2.8%	$31.20	0.0%	COM	90184D100
ADPT	ADAPTIVE BIOTECHNOLOGIES COR	606,825	$9,855	1.7%	$16.32	0.0%	COM	00650F109
PALI	PALISADE BIO INC	4,192,375	$9,852	1.7%	$1.92	0.0%	COM	696389402
CYTK	CYTOKINETICS INC	146,978	$9,339	1.6%	$62.21	0.0%	COM NEW	23282W605
EWTX	EDGEWISE THERAPEUTICS INC	360,876	$8,955	1.5%	$20.07	0.0%	COM	28036F105
DRUG	BRIGHT MINDS BIOSCIENCES INC	97,340	$7,596	1.3%	$66.83	0.0%	COM NEW	10919W405
JNJ	JOHNSON & JOHNSON	35,000	$7,243	1.2%	$197.01	0.0%	COM	478160104
EYPT	EYEPOINT INC	353,849	$6,465	1.1%	$14.17	0.0%	COM NEW	30233G209
IMTX	IMMATICS N.V	610,308	$6,408	1.1%	$10.09	0.0%	SHS	N44445109
PRAX	PRAXIS PRECISION MEDICINES I	21,067	$6,209	1.1%	$186.22	0.0%	COM NEW	74006W207
APGE	APOGEE THERAPEUTICS INC	80,574	$6,082	1.0%	$62.99	0.0%	COM	03770N101
MAZE	MAZE THERAPEUTICS INC	125,877	$5,215	0.9%	$34.37	0.0%	COM	578784100
LLY	ELI LILLY & CO	4,759	$5,114	0.9%	$955.55	0.0%	COM	532457108
VRDN	VIRIDIAN THERAPEUTICS INC	154,320	$4,802	0.8%	$27.43	0.0%	COM	92790C104
MLTX	MOONLAKE IMMUNOTHERAPEUTICS	348,401	$4,592	0.8%	$11.80	0.0%	CLASS A ORD	61559X104
CTMX	CYTOMX THERAPEUTICS INC	1,036,311	$4,415	0.8%	$3.80	0.0%	COM	23284F105
RGEN	REPLIGEN CORP	15,707	$2,574	0.4%	$156.63	0.0%	COM	759916109
QNCX	QUINCE THERAPEUTICS INC	739,264	$2,477	0.4%	$2.52	0.0%	COM	22053A107
AVTX	AVALO THERAPEUTICS INC	135,552	$2,462	0.4%	$16.88	0.0%	COM NEW	05338F306
ABBV	ABBVIE INC	9,325	$2,131	0.4%	$227.54	0.0%	COM	00287Y109
MPLT	MAPLIGHT THERAPEUTICS INC	100,000	$1,757	0.3%	$16.75	0.0%	COM	56565P103
PHVS	PHARVARIS N V	58,389	$1,620	0.3%	$24.09	0.0%	COM	N69605108
LEGN	LEGEND BIOTECH CORP	73,328	$1,594	0.3%	$21.74	—	SPONSORED ADS	52490G102
BLTE	BELITE BIO INC	9,163	$1,466	0.3%	$159.96	—	SPONSORED ADS	07782B104
XLO	XILIO THERAPEUTICS INC	2,030,028	$1,300	0.2%	$0.75	0.0%	COM	98422T100
EVMN	EVOMMUNE INC	68,196	$1,168	0.2%	$18.78	0.0%	COM SHS	30054Y107
SYRE	SPYRE THERAPEUTICS INC	32,377	$1,061	0.2%	$26.13	0.0%	COM NEW	00773J202
GLUE	MONTE ROSA THERAPEUTICS INC	61,577	$966	0.2%	$13.48	0.0%	COM	61225M102
SABS	SAB BIOTHERAPEUTICS INC	146,558	$548	0.1%	$3.29	0.0%	COM NEW	78397T202
VNDA	VANDA PHARMACEUTICALS INC	58,989	$520	0.1%	$5.50	0.0%	COM	921659108
CAPR	CAPRICOR THERAPEUTICS INC	17,853	$515	0.1%	$13.06	0.0%	COM NEW	14070B309
KTTA	PASITHEA THERAPEUTICS CORP	355,082	$458	0.1%	$0.88	0.0%	COM NEW	70261F202

Increased Positions (28)

ABVX ABIVAX SA 9.1%

Value ($000) $52,834 (+274.3%) Shares 391,783 (+135.6%) Est. Cost $96.35 Unrealized —

GPCR STRUCTURE THERAPEUTICS INC 4.2%

Value ($000) $24,417 (+574.2%) Shares 351,073 (+171.4%) Est. Cost $54.24 Unrealized —

ACLX ARCELLX INC 3.7%

Value ($000) $21,702 (+2223.7%) Shares 332,860 (+2826.0%) Est. Cost $79.36 Unrealized +0.5%

TERN TERNS PHARMACEUTICALS INC 3.0%

Value ($000) $17,340 (+2476.4%) Shares 429,198 (+378.9%) Est. Cost $19.62 Unrealized +17.8%

CNTA CENTESSA PHARMACEUTICALS PLC 4.9%

Value ($000) $28,864 (+81.6%) Shares 1,154,114 (+76.1%) Est. Cost $19.20 Unrealized —

SRRK SCHOLAR ROCK HLDG CORP 6.7%

Value ($000) $39,068 (+44.5%) Shares 886,893 (+22.1%) Est. Cost $36.48 Unrealized +2.8%

DYN DYNE THERAPEUTICS INC 2.8%

Value ($000) $16,337 (+172.1%) Shares 835,200 (+76.0%) Est. Cost $14.66 Unrealized +29.2%

XENE XENON PHARMACEUTICALS INC 2.7%

Value ($000) $15,624 (+102.4%) Shares 348,605 (+81.3%) Est. Cost $38.26 Unrealized +9.8%

MDGL MADRIGAL PHARMACEUTICALS INC 1.8%

Value ($000) $10,328 (+174.4%) Shares 17,736 (+116.1%) Est. Cost $423.30 Unrealized +20.7%

CLPT CLEARPOINT NEURO INC 1.1%

Value ($000) $6,592 (+1716.8%) Shares 481,858 (+2793.9%) Est. Cost $18.30 Unrealized +1.3%

MLYS MINERALYS THERAPEUTICS INC 1.8%

Value ($000) $10,526 (+75.6%) Shares 290,049 (+83.4%) Est. Cost $26.14 Unrealized +53.4%

NKTR NEKTAR THERAPEUTICS 1.3%

Value ($000) $7,537 (+149.0%) Shares 178,274 (+235.1%) Est. Cost $49.14 Unrealized +13.9%

ABUS ARBUTUS BIOPHARMA CORP 0.8%

Value ($000) $4,746 (+409.0%) Shares 986,751 (+380.4%) Est. Cost $4.33 Unrealized +4.0%

ASMB ASSEMBLY BIOSCIENCES INC 0.9%

Value ($000) $5,330 (+214.9%) Shares 156,728 (+137.0%) Est. Cost $27.88 Unrealized +15.5%

AMLX AMYLYX PHARMACEUTICALS INC 1.2%

Value ($000) $6,827 (+81.5%) Shares 565,140 (+104.1%) Est. Cost $11.54 Unrealized +17.7%

WHWK WHITEHAWK THERAPEUTICS INC 0.6%

Value ($000) $3,530 (+338.1%) Shares 1,458,807 (+244.0%) Est. Cost $2.16 Unrealized +6.1%

INCY INCYTE CORP 1.0%

Value ($000) $6,068 (+63.5%) Shares 61,435 (+40.4%) Est. Cost $84.14 Unrealized +15.0%

OCUL OCULAR THERAPEUTIX INC 1.1%

Value ($000) $6,345 (+51.0%) Shares 522,693 (+45.4%) Est. Cost $12.02 Unrealized +1.1%

IVVD INVIVYD INC 0.4%

Value ($000) $2,445 (+697.8%) Shares 989,822 (+255.3%) Est. Cost $1.74 Unrealized +19.3%

PTGX PROTAGONIST THERAPEUTICS INC 0.9%

Value ($000) $5,191 (+62.9%) Shares 59,430 (+23.9%) Est. Cost $57.93 Unrealized +41.3%

IVA INVENTIVA SA 0.4%

Value ($000) $2,173 (+1117.4%) Shares 467,242 (+1415.8%) Est. Cost $4.73 Unrealized —

TRVI TREVI THERAPEUTICS INC 0.9%

Value ($000) $5,002 (+55.9%) Shares 399,557 (+13.9%) Est. Cost $7.99 Unrealized +44.6%

XFOR X4 PHARMACEUTICALS INC 0.6%

Value ($000) $3,594 (+89.2%) Shares 898,465 (+61.8%) Est. Cost $2.98 Unrealized +21.9%

DNTH DIANTHUS THERAPEUTICS INC 0.6%

Value ($000) $3,267 (+100.6%) Shares 79,284 (+91.6%) Est. Cost $31.87 Unrealized +21.6%

MGTX MEIRAGTX HLDGS PLC 0.4%

Value ($000) $2,287 (+239.5%) Shares 287,689 (+251.4%) Est. Cost $8.20 Unrealized +1.4%

MBX MBX BIOSCIENCES INC 0.4%

Value ($000) $2,478 (+88.8%) Shares 78,553 (+4.7%) Est. Cost $11.08 Unrealized +119.1%

ADCT ADC THERAPEUTICS SA 0.3%

Value ($000) $1,774 (+56.6%) Shares 502,570 (+77.4%) Est. Cost $2.96 Unrealized +37.3%

SRRK SCHOLAR ROCK HLDG CORP 0.1%

Value ($000) $485 (+1926.5%) Shares 277,000 (+1405.4%) Est. Cost $36.48 Unrealized +2.8%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
ABVX	ABIVAX SA	391,783 (+135.6%)	$52,834 (+274.3%)	9.1%	$96.35	—	SPONSORED ADS	00370M103
GPCR	STRUCTURE THERAPEUTICS INC	351,073 (+171.4%)	$24,417 (+574.2%)	4.2%	$54.24	—	SPONSORED ADS	86366E106
ACLX	ARCELLX INC	332,860 (+2826.0%)	$21,702 (+2223.7%)	3.7%	$79.36	+0.5%	COMMON STOCK	03940C100
TERN	TERNS PHARMACEUTICALS INC	429,198 (+378.9%)	$17,340 (+2476.4%)	3.0%	$19.62	+17.8%	COM	880881107
CNTA	CENTESSA PHARMACEUTICALS PLC	1,154,114 (+76.1%)	$28,864 (+81.6%)	4.9%	$19.20	—	SPONSORED ADS	152309100
SRRK	SCHOLAR ROCK HLDG CORP	886,893 (+22.1%)	$39,068 (+44.5%)	6.7%	$36.48	+2.8%	COM	80706P103
DYN	DYNE THERAPEUTICS INC	835,200 (+76.0%)	$16,337 (+172.1%)	2.8%	$14.66	+29.2%	COM	26818M108
XENE	XENON PHARMACEUTICALS INC	348,605 (+81.3%)	$15,624 (+102.4%)	2.7%	$38.26	+9.8%	COM	98420N105
MDGL	MADRIGAL PHARMACEUTICALS INC	17,736 (+116.1%)	$10,328 (+174.4%)	1.8%	$423.30	+20.7%	COM	558868105
CLPT	CLEARPOINT NEURO INC	481,858 (+2793.9%)	$6,592 (+1716.8%)	1.1%	$18.30	+1.3%	COM	18507C103
MLYS	MINERALYS THERAPEUTICS INC	290,049 (+83.4%)	$10,526 (+75.6%)	1.8%	$26.14	+53.4%	COM	603170101
NKTR	NEKTAR THERAPEUTICS	178,274 (+235.1%)	$7,537 (+149.0%)	1.3%	$49.14	+13.9%	COM NEW	640268306
ABUS	ARBUTUS BIOPHARMA CORP	986,751 (+380.4%)	$4,746 (+409.0%)	0.8%	$4.33	+4.0%	COM	03879J100
ASMB	ASSEMBLY BIOSCIENCES INC	156,728 (+137.0%)	$5,330 (+214.9%)	0.9%	$27.88	+15.5%	COM NEW	045396207
AMLX	AMYLYX PHARMACEUTICALS INC	565,140 (+104.1%)	$6,827 (+81.5%)	1.2%	$11.54	+17.7%	COM	03237H101
WHWK	WHITEHAWK THERAPEUTICS INC	1,458,807 (+244.0%)	$3,530 (+338.1%)	0.6%	$2.16	+6.1%	COM	00032Q104
INCY	INCYTE CORP	61,435 (+40.4%)	$6,068 (+63.5%)	1.0%	$84.14	+15.0%	COM	45337C102
OCUL	OCULAR THERAPEUTIX INC	522,693 (+45.4%)	$6,345 (+51.0%)	1.1%	$12.02	+1.1%	COM	67576A100
IVVD	INVIVYD INC	989,822 (+255.3%)	$2,445 (+697.8%)	0.4%	$1.74	+19.3%	COM	00534A102
PTGX	PROTAGONIST THERAPEUTICS INC	59,430 (+23.9%)	$5,191 (+62.9%)	0.9%	$57.93	+41.3%	COM	74366E102
IVA	INVENTIVA SA	467,242 (+1415.8%)	$2,173 (+1117.4%)	0.4%	$4.73	—	ADS	46124U107
TRVI	TREVI THERAPEUTICS INC	399,557 (+13.9%)	$5,002 (+55.9%)	0.9%	$7.99	+44.6%	COM	89532M101
XFOR	X4 PHARMACEUTICALS INC	898,465 (+61.8%)	$3,594 (+89.2%)	0.6%	$2.98	+21.9%	COM NEW	98420X202
DNTH	DIANTHUS THERAPEUTICS INC	79,284 (+91.6%)	$3,267 (+100.6%)	0.6%	$31.87	+21.6%	COM	252828108
MGTX	MEIRAGTX HLDGS PLC	287,689 (+251.4%)	$2,287 (+239.5%)	0.4%	$8.20	+1.4%	COM	G59665102
MBX	MBX BIOSCIENCES INC	78,553 (+4.7%)	$2,478 (+88.8%)	0.4%	$11.08	+119.1%	COM	55287L101
ADCT	ADC THERAPEUTICS SA	502,570 (+77.4%)	$1,774 (+56.6%)	0.3%	$2.96	+37.3%	SHS	H0036K147
SRRK	SCHOLAR ROCK HLDG CORP	277,000 (+1405.4%)	$485 (+1926.5%)	0.1%	$36.48	+2.8%	CALL	80706P103

Exited Positions (42)

WVE WAVE LIFE SCIENCES LTD 2.6%

Value ($000) $15,446 Shares 2,110,152 Est. Cost $7.61 Unrealized +33.5%

BHVN BIOHAVEN LTD 2.6%

Value ($000) $15,270 Shares 1,017,311 Est. Cost $18.27 Unrealized -32.2%

— CIDARA THERAPEUTICS INC 2.5%

Value ($000) $14,587 Shares 152,325 Est. Cost $48.71 Unrealized —

ARGX ARGENX SE 1.6%

Value ($000) $9,194 Shares 12,465 Est. Cost $737.56 Unrealized —

RZLT REZOLUTE INC 1.5%

Value ($000) $8,626 Shares 917,630 Est. Cost $4.59 Unrealized +70.8%

GHRS GH RESEARCH PLC 1.3%

Value ($000) $7,797 Shares 545,275 Est. Cost $13.43 Unrealized +1.4%

ALKS ALKERMES PLC 1.2%

Value ($000) $7,249 Shares 241,637 Est. Cost $29.07 Unrealized +3.0%

BBIO BRIDGEBIO PHARMA INC 1.1%

Value ($000) $6,619 Shares 127,435 Est. Cost $42.32 Unrealized +55.1%

INSM INSMED INC 1.1%

Value ($000) $6,251 Shares 43,419 Est. Cost $72.02 Unrealized +153.4%

— AKERO THERAPEUTICS INC 1.0%

Value ($000) $5,765 Shares 121,410 Est. Cost $40.75 Unrealized —

JAZZ JAZZ PHARMACEUTICALS PLC 0.9%

Value ($000) $5,150 Shares 39,072 Est. Cost $119.94 Unrealized +27.8%

RNA AVIDITY BIOSCIENCES INC 0.9%

Value ($000) $4,969 Shares 114,053 Est. Cost $40.43 Unrealized +59.8%

TECX TECTONIC THERAPEUTIC INC 0.5%

Value ($000) $2,965 Shares 188,999 Est. Cost $20.56 Unrealized -9.6%

HROW HARROW INC 0.5%

Value ($000) $2,776 Shares 57,619 Est. Cost $37.67 Unrealized +11.4%

EQ EQUILLIUM INC 0.5%

Value ($000) $2,730 Shares 1,908,935 Est. Cost $1.06 Unrealized +15.1%

UTHR UNITED THERAPEUTICS CORP DEL 0.5%

Value ($000) $2,626 Shares 6,264 Est. Cost $336.31 Unrealized +38.5%

CGON CG ONCOLOGY INC 0.4%

Value ($000) $2,538 Shares 63,019 Est. Cost $29.07 Unrealized +42.3%

QQQ INVESCO QQQ TR 0.4%

Value ($000) $2,280 Shares 3,797 Est. Cost $600.37 Unrealized —

TNGX TANGO THERAPEUTICS INC 0.4%

Value ($000) $2,061 Shares 245,378 Est. Cost $3.11 Unrealized +176.8%

ORIC ORIC PHARMACEUTICALS INC 0.3%

Value ($000) $1,998 Shares 166,461 Est. Cost $6.71 Unrealized +71.5%

PEPG PEPGEN INC 0.3%

Value ($000) $1,798 Shares 389,189 Est. Cost $1.61 Unrealized +222.0%

PCSC PERCEPTIVE CAP SOLUTIONS COR 0.3%

Value ($000) $1,590 Shares 150,000 Est. Cost $10.07 Unrealized +11.9%

TARA PROTARA THERAPEUTICS INC 0.3%

Value ($000) $1,582 Shares 363,666 Est. Cost $4.05 Unrealized +37.2%

CMPS COMPASS PATHWAYS PLC 0.3%

Value ($000) $1,579 Shares 275,620 Est. Cost $5.73 Unrealized —

PYXS PYXIS ONCOLOGY INC 0.3%

Value ($000) $1,531 Shares 689,538 Est. Cost $1.44 Unrealized +144.9%

BHVN BIOHAVEN LTD 0.2%

Value ($000) $1,188 Shares 480,000 Est. Cost $18.27 Unrealized -32.2%

— MIND MEDICINE MINDMED INC 0.2%

Value ($000) $906 Shares 76,875 Est. Cost $6.49 Unrealized —

ENTA ENANTA PHARMACEUTICALS INC 0.2%

Value ($000) $900 Shares 75,194 Est. Cost $7.99 Unrealized +58.9%

ZBIO ZENAS BIOPHARMA INC 0.1%

Value ($000) $860 Shares 38,742 Est. Cost $16.28 Unrealized +102.0%

XBI SPDR SERIES TRUST 0.1%

Value ($000) $725 Shares 1,490,100 Est. Cost — Unrealized —

CRVS CORVUS PHARMACEUTICALS INC 0.1%

Value ($000) $711 Shares 96,439 Est. Cost $5.12 Unrealized +54.1%

KALV KALVISTA PHARMACEUTICALS INC 0.1%

Value ($000) $691 Shares 56,770 Est. Cost $10.36 Unrealized +27.9%

ARCT ARCTURUS THERAPEUTICS HLDGS 0.1%

Value ($000) $656 Shares 35,606 Est. Cost $16.06 Unrealized -32.8%

VTYX VENTYX BIOSCIENCES INC 0.1%

Value ($000) $521 Shares 167,470 Est. Cost $2.65 Unrealized +182.1%

— ATAI LIFE SCIENCES NV 0.1%

Value ($000) $402 Shares 76,032 Est. Cost $5.29 Unrealized —

IONS IONIS PHARMACEUTICALS INC 0.0%

Value ($000) $138 Shares 50,000 Est. Cost — Unrealized —

CRSP CRISPR THERAPEUTICS AG 0.0%

Value ($000) $59 Shares 40,000 Est. Cost — Unrealized —

SNDX SYNDAX PHARMACEUTICALS INC 0.0%

Value ($000) $55 Shares 100,000 Est. Cost $15.22 Unrealized +14.7%

IMVT IMMUNOVANT INC 0.0%

Value ($000) $50 Shares 250,000 Est. Cost $24.09 Unrealized -7.4%

ARKG ARK ETF TR 0.0%

Value ($000) $30 Shares 200,000 Est. Cost — Unrealized —

— AKERO THERAPEUTICS INC 0.0%

Value ($000) $10 Shares 15,500 Est. Cost $40.75 Unrealized —

ABUS ARBUTUS BIOPHARMA CORP 0.0%

Value ($000) $10 Shares 95,000 Est. Cost $4.33 Unrealized +4.0%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
WVE	WAVE LIFE SCIENCES LTD	2,110,152	$15,446	2.6%	$7.61	+33.5%	—	Y95308105
BHVN	BIOHAVEN LTD	1,017,311	$15,270	2.6%	$18.27	-32.2%	—	G1110E107
—	CIDARA THERAPEUTICS INC	152,325	$14,587	2.5%	$48.71	—	—	171757206
ARGX	ARGENX SE	12,465	$9,194	1.6%	$737.56	—	—	04016X101
RZLT	REZOLUTE INC	917,630	$8,626	1.5%	$4.59	+70.8%	—	76200L309
GHRS	GH RESEARCH PLC	545,275	$7,797	1.3%	$13.43	+1.4%	—	G3855L106
ALKS	ALKERMES PLC	241,637	$7,249	1.2%	$29.07	+3.0%	—	G01767105
BBIO	BRIDGEBIO PHARMA INC	127,435	$6,619	1.1%	$42.32	+55.1%	—	10806X102
INSM	INSMED INC	43,419	$6,251	1.1%	$72.02	+153.4%	—	457669307
—	AKERO THERAPEUTICS INC	121,410	$5,765	1.0%	$40.75	—	—	00973Y108
JAZZ	JAZZ PHARMACEUTICALS PLC	39,072	$5,150	0.9%	$119.94	+27.8%	—	G50871105
RNA	AVIDITY BIOSCIENCES INC	114,053	$4,969	0.9%	$40.43	+59.8%	—	05370A108
TECX	TECTONIC THERAPEUTIC INC	188,999	$2,965	0.5%	$20.56	-9.6%	—	878972108
HROW	HARROW INC	57,619	$2,776	0.5%	$37.67	+11.4%	—	415858109
EQ	EQUILLIUM INC	1,908,935	$2,730	0.5%	$1.06	+15.1%	—	29446K106
UTHR	UNITED THERAPEUTICS CORP DEL	6,264	$2,626	0.5%	$336.31	+38.5%	—	91307C102
CGON	CG ONCOLOGY INC	63,019	$2,538	0.4%	$29.07	+42.3%	—	156944100
QQQ	INVESCO QQQ TR	3,797	$2,280	0.4%	$600.37	—	—	46090E103
TNGX	TANGO THERAPEUTICS INC	245,378	$2,061	0.4%	$3.11	+176.8%	—	87583X109
ORIC	ORIC PHARMACEUTICALS INC	166,461	$1,998	0.3%	$6.71	+71.5%	—	68622P109
PEPG	PEPGEN INC	389,189	$1,798	0.3%	$1.61	+222.0%	—	713317105
PCSC	PERCEPTIVE CAP SOLUTIONS COR	150,000	$1,590	0.3%	$10.07	+11.9%	—	G70077105
TARA	PROTARA THERAPEUTICS INC	363,666	$1,582	0.3%	$4.05	+37.2%	—	74365U107
CMPS	COMPASS PATHWAYS PLC	275,620	$1,579	0.3%	$5.73	—	—	20451W101
PYXS	PYXIS ONCOLOGY INC	689,538	$1,531	0.3%	$1.44	+144.9%	—	747324101
BHVN	BIOHAVEN LTD	480,000	$1,188	0.2%	$18.27	-32.2%	CALL	G1110E107
—	MIND MEDICINE MINDMED INC	76,875	$906	0.2%	$6.49	—	—	60255C885
ENTA	ENANTA PHARMACEUTICALS INC	75,194	$900	0.2%	$7.99	+58.9%	—	29251M106
ZBIO	ZENAS BIOPHARMA INC	38,742	$860	0.1%	$16.28	+102.0%	—	98937L105
XBI	SPDR SERIES TRUST	1,490,100	$725	0.1%	—	—	PUT	78464A870
CRVS	CORVUS PHARMACEUTICALS INC	96,439	$711	0.1%	$5.12	+54.1%	—	221015100
KALV	KALVISTA PHARMACEUTICALS INC	56,770	$691	0.1%	$10.36	+27.9%	—	483497103
ARCT	ARCTURUS THERAPEUTICS HLDGS	35,606	$656	0.1%	$16.06	-32.8%	—	03969T109
VTYX	VENTYX BIOSCIENCES INC	167,470	$521	0.1%	$2.65	+182.1%	—	92332V107
—	ATAI LIFE SCIENCES NV	76,032	$402	0.1%	$5.29	—	—	N0731H103
IONS	IONIS PHARMACEUTICALS INC	50,000	$138	0.0%	—	—	CALL	462222100
CRSP	CRISPR THERAPEUTICS AG	40,000	$59	0.0%	—	—	CALL	H17182108
SNDX	SYNDAX PHARMACEUTICALS INC	100,000	$55	0.0%	$15.22	+14.7%	CALL	87164F105
IMVT	IMMUNOVANT INC	250,000	$50	0.0%	$24.09	-7.4%	CALL	45258J102
ARKG	ARK ETF TR	200,000	$30	0.0%	—	—	CALL	00214Q302
—	AKERO THERAPEUTICS INC	15,500	$10	0.0%	$40.75	—	PUT	00973Y108
ABUS	ARBUTUS BIOPHARMA CORP	95,000	$10	0.0%	$4.33	+4.0%	CALL	03879J100

Decreased Positions (17)

ROIV ROIVANT SCIENCES LTD 3.6%

Value ($000) $20,977 (-67.0%) Shares 966,698 (-77.0%) Est. Cost $12.06 Unrealized +63.5%

QURE UNIQURE NV 0.2%

Value ($000) $1,041 (-96.6%) Shares 43,485 (-91.7%) Est. Cost $13.36 Unrealized +188.8%

DNLI DENALI THERAPEUTICS INC 1.2%

Value ($000) $6,919 (-72.5%) Shares 419,058 (-75.8%) Est. Cost $17.43 Unrealized -3.2%

IMVT IMMUNOVANT INC 2.8%

Value ($000) $16,395 (-36.0%) Shares 644,959 (-59.4%) Est. Cost $24.09 Unrealized -7.4%

VTGN VISTAGEN THERAPEUTICS INC 0.0%

Value ($000) $142 (-98.2%) Shares 616,749 (-75.2%) Est. Cost $3.55 Unrealized +1.7%

SNDX SYNDAX PHARMACEUTICALS INC 4.8%

Value ($000) $28,140 (+33.9%) Shares 1,339,379 (-2.0%) Est. Cost $15.22 Unrealized +14.7%

CELC CELCUITY INC 2.0%

Value ($000) $11,803 (+74.8%) Shares 118,333 (-13.4%) Est. Cost $40.03 Unrealized +105.4%

IDYA IDEAYA BIOSCIENCES INC 1.0%

Value ($000) $5,589 (-44.8%) Shares 161,659 (-56.5%) Est. Cost $22.34 Unrealized +42.7%

RVMD REVOLUTION MEDICINES INC 0.8%

Value ($000) $4,941 (-42.9%) Shares 62,032 (-66.5%) Est. Cost $39.15 Unrealized +67.5%

SRZN SURROZEN INC 2.2%

Value ($000) $12,672 (+37.8%) Shares 619,766 (-13.1%) Est. Cost $9.58 Unrealized +68.9%

RYTM RHYTHM PHARMACEUTICALS INC 1.1%

Value ($000) $6,306 (-31.7%) Shares 58,915 (-35.6%) Est. Cost $59.81 Unrealized +77.4%

TSHA TAYSHA GENE THERAPIES INC 0.2%

Value ($000) $1,002 (-63.5%) Shares 182,130 (-78.3%) Est. Cost $2.17 Unrealized +123.5%

NAMS NEWAMSTERDAM PHARMA COMPANY 0.4%

Value ($000) $2,565 (-40.1%) Shares 73,106 (-51.4%) Est. Cost $20.97 Unrealized +73.5%

ARQT ARCUTIS BIOTHERAPEUTICS INC 1.1%

Value ($000) $6,526 (-15.9%) Shares 224,740 (-45.4%) Est. Cost $10.89 Unrealized +135.2%

BBOT BRIDGEBIO ONCOLOGY THERAPEUT 0.2%

Value ($000) $1,083 (-49.9%) Shares 86,517 (-53.6%) Est. Cost $11.58 Unrealized —

CNTA CENTESSA PHARMACEUTICALS PLC 0.0%

Value ($000) $26 (-97.1%) Shares 75,000 (-56.5%) Est. Cost $19.20 Unrealized —

ASND ASCENDIS PHARMA A/S 0.5%

Value ($000) $3,165 (+5.1%) Shares 14,842 (-2.0%) Est. Cost $198.81 Unrealized —

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
ROIV	ROIVANT SCIENCES LTD	966,698 (-77.0%)	$20,977 (-67.0%)	3.6%	$12.06	+63.5%	SHS	G76279101
QURE	UNIQURE NV	43,485 (-91.7%)	$1,041 (-96.6%)	0.2%	$13.36	+188.8%	SHS	N90064101
DNLI	DENALI THERAPEUTICS INC	419,058 (-75.8%)	$6,919 (-72.5%)	1.2%	$17.43	-3.2%	COM	24823R105
IMVT	IMMUNOVANT INC	644,959 (-59.4%)	$16,395 (-36.0%)	2.8%	$24.09	-7.4%	COM	45258J102
VTGN	VISTAGEN THERAPEUTICS INC	616,749 (-75.2%)	$142 (-98.2%)	0.0%	$3.55	+1.7%	COM	92840H400
SNDX	SYNDAX PHARMACEUTICALS INC	1,339,379 (-2.0%)	$28,140 (+33.9%)	4.8%	$15.22	+14.7%	COM	87164F105
CELC	CELCUITY INC	118,333 (-13.4%)	$11,803 (+74.8%)	2.0%	$40.03	+105.4%	COM	15102K100
IDYA	IDEAYA BIOSCIENCES INC	161,659 (-56.5%)	$5,589 (-44.8%)	1.0%	$22.34	+42.7%	COM	45166A102
RVMD	REVOLUTION MEDICINES INC	62,032 (-66.5%)	$4,941 (-42.9%)	0.8%	$39.15	+67.5%	COM	76155X100
SRZN	SURROZEN INC	619,766 (-13.1%)	$12,672 (+37.8%)	2.2%	$9.58	+68.9%	COM NEW	86889P208
RYTM	RHYTHM PHARMACEUTICALS INC	58,915 (-35.6%)	$6,306 (-31.7%)	1.1%	$59.81	+77.4%	COM	76243J105
TSHA	TAYSHA GENE THERAPIES INC	182,130 (-78.3%)	$1,002 (-63.5%)	0.2%	$2.17	+123.5%	COM SHS	877619106
NAMS	NEWAMSTERDAM PHARMA COMPANY	73,106 (-51.4%)	$2,565 (-40.1%)	0.4%	$20.97	+73.5%	ORDINARY SHARES	N62509109
ARQT	ARCUTIS BIOTHERAPEUTICS INC	224,740 (-45.4%)	$6,526 (-15.9%)	1.1%	$10.89	+135.2%	COM	03969K108
BBOT	BRIDGEBIO ONCOLOGY THERAPEUT	86,517 (-53.6%)	$1,083 (-49.9%)	0.2%	$11.58	—	COM NEW	107924102
CNTA	CENTESSA PHARMACEUTICALS PLC	75,000 (-56.5%)	$26 (-97.1%)	0.0%	$19.20	—	CALL	152309100
ASND	ASCENDIS PHARMA A/S	14,842 (-2.0%)	$3,165 (+5.1%)	0.5%	$198.81	—	SPONSORED ADR	04351P101