Location: New York, NY
CIK: 0001263508 · Show all filings
Period: Q1 2025 (← Previous) (Next →)
Filing Date: May 15, 2025
Total Value: $9.037B (98.9% shares, 1.1% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| ONC | BeiGene, Ltd. | 8,799,053 | $2.395B | 26.5% | $136.93 | — | SPONSORED ADR | 07725L102 |
| INCY | Incyte Corporation | 30,739,953 | $1.861B | 20.6% | $72.80 | -4.2% | COM | 45337C102 |
| ACAD | ACADIA Pharmaceuticals Inc. | 42,877,916 | $712M | 7.9% | $18.93 | -4.0% | COM | 004225108 |
| MDGL | Madrigal Pharmaceuticals, Inc. | 1,974,590 | $654M | 7.2% | $119.77 | +174.3% | COM | 558868105 |
| SMMT | Summit Therapeutics Inc. | 24,424,865 | $471M | 5.2% | $5.82 | +244.5% | COM | 86627T108 |
| INSM | Insmed Incorporated | 5,380,626 | $410M | 4.5% | $49.30 | +55.2% | COM PAR $.01 | 457669307 |
| RYTM | Rhythm Pharmaceuticals, Inc. | 5,604,483 | $297M | 3.3% | $23.49 | +136.2% | COM | 76243J105 |
| RVMD | Revolution Medicines, Inc. | 7,936,972 | $281M | 3.1% | $27.73 | +46.4% | COM | 76155X100 |
| KYMR | Kymera Therapeutics, Inc. | 5,995,929 | $164M | 1.8% | $28.14 | +29.6% | COM | 501575104 |
| ALKS | Alkermes plc | 4,483,285 | $148M | 1.6% | $25.07 | +30.1% | SHS | G01767105 |
| EWTX | Edgewise Therapeutics, Inc. | 6,155,940 | $135M | 1.5% | $14.27 | +83.8% | COM | 28036F105 |
| REPL | Replimune Group, Inc. | 11,045,336 | $108M | 1.2% | $14.45 | -14.4% | COM | 76029N106 |
| — | Insmed Incorporated | 42,850,000 | $102M | 1.1% | $2.11 | — | Note 0.75% 6/1/2028 | 457669AB5 |
| IMVT | Immunovant, Inc. | 5,457,881 | $93.28M | 1.0% | $22.96 | -8.9% | COM | 45258J102 |
| BCYC | Bicycle Therapeutics plc | 10,885,357 | $92.42M | 1.0% | $20.78 | — | SPONSORED ADS | 088786108 |
| IMCR | Immunocore Holdings plc | 2,322,656 | $68.91M | 0.8% | $38.09 | — | ADS | 45258D105 |
| KNSA | Kiniksa Pharmaceuticals International, plc | 2,818,323 | $62.59M | 0.7% | $18.73 | +9.9% | ORD SHS CL A | G52694109 |
| ABCL | AbCellera Biologics Inc. | 27,525,640 | $61.38M | 0.7% | $21.02 | -86.4% | COM | 00288U106 |
| RARE | Ultragenyx Pharmaceutical Inc. | 1,576,114 | $57.07M | 0.6% | $64.34 | -35.3% | COM | 90400D108 |
| DNLI | Denali Therapeutics Inc. | 3,731,695 | $50.73M | 0.6% | $23.78 | -19.4% | COM | 24823R105 |
| KOD | Kodiak Sciences Inc. | 17,310,490 | $48.56M | 0.5% | $30.30 | -82.1% | COM | 50015M109 |
| NRIX | Nurix Therapeutics, Inc. | 3,882,125 | $46.12M | 0.5% | $22.27 | -24.9% | COM | 67080M103 |
| ARGX | argenx SE | 77,760 | $46.02M | 0.5% | $79.01 | — | SPONSORED ADR | 04016X101 |
| TRDA | Entrada Therapeutics, Inc. | 4,865,819 | $43.99M | 0.5% | $16.96 | — | COM | 29384C108 |
| CELC | Celcuity Inc. | 4,257,735 | $43.05M | 0.5% | $13.18 | -14.1% | COM | 15102K100 |
| GRAL | GRAIL, Inc. | 1,630,125 | $41.63M | 0.5% | $16.26 | +90.0% | COM | 384747101 |
| ROIV | Roivant Sciences Ltd. | 3,767,773 | $38.02M | 0.4% | $9.71 | +11.3% | SHS | G76279101 |
| IMTX | Immatics N.V. | 7,275,830 | $32.81M | 0.4% | $10.61 | -50.8% | SHS | N44445109 |
| STOK | Stoke Therapeutics, Inc. | 4,633,838 | $30.82M | 0.3% | $9.30 | +0.2% | COM | 86150R107 |
| CERS | Cerus Corporation | 19,351,087 | $26.9M | 0.3% | $4.19 | -60.0% | COM | 157085101 |
| PCVX | Vaxcyte, Inc. | 640,885 | $24.2M | 0.3% | $76.85 | +4.0% | COM | 92243G108 |
| GLUE | Monte Rosa Therapeutics, Inc. | 4,916,095 | $22.81M | 0.3% | $6.49 | -5.6% | COM | 61225M102 |
| CRSP | CRISPR Therapeutics AG | 654,099 | $22.26M | 0.2% | $50.03 | -15.3% | NAMEN AKT | H17182108 |
| — | Akero Therapeutics, Inc. | 548,713 | $22.21M | 0.2% | $32.79 | — | COM | 00973Y108 |
| SERA | Sera Prognostics, Inc. | 5,498,170 | $20.23M | 0.2% | $3.09 | +64.6% | CLASS A COM | 81749D107 |
| CNTA | Centessa Pharmaceuticals plc | 1,227,178 | $17.65M | 0.2% | $12.88 | — | SPONSORED ADS | 152309100 |
| NGNE | Neurogene Inc. | 1,486,200 | $17.4M | 0.2% | $19.35 | -10.2% | COM | 64135M105 |
| IDYA | IDEAYA Biosciences, Inc. | 1,062,123 | $17.4M | 0.2% | $14.62 | +45.7% | COM | 45166A102 |
| — | Verona Pharma plc | 223,843 | $14.21M | 0.2% | $63.49 | — | SPONSORED ADS | 925050106 |
| CADL | Candel Therapeutics, Inc. | 2,437,189 | $13.77M | 0.2% | $5.91 | +38.3% | COM | 137404109 |
| PRAX | Praxis Precision Medicines, Inc. | 331,533 | $12.56M | 0.1% | $50.85 | +22.8% | COM | 74006W207 |
| — | 2seventy bio, Inc. | 2,497,526 | $12.34M | 0.1% | $18.72 | — | COMMON STOCK | 901384107 |
| XENE | Xenon Pharmaceuticals Inc. | 347,408 | $11.66M | 0.1% | $18.51 | +105.2% | COM | 98420N105 |
| BCAX | Bicara Therapeutics Inc. | 833,333 | $10.86M | 0.1% | $25.50 | -47.9% | COM | 055477103 |
| IONS | Ionis Pharmaceuticals, Inc. | 357,915 | $10.8M | 0.1% | $43.09 | -24.0% | COM | 462222100 |
| DBVT | DBV Technologies S.A. | 1,461,425 | $9.967M | 0.1% | $3.09 | — | SPONSORED ADS | 23306J309 |
| ALMS | Alumis Inc. | 1,562,500 | $9.594M | 0.1% | $13.30 | -56.3% | COM | 022307102 |
| — | Merus N.V. | 223,500 | $9.407M | 0.1% | $53.46 | — | COM | N5749R100 |
| PRLD | Prelude Therapeutics Inc. | 10,123,824 | $7.775M | 0.1% | $28.24 | -96.7% | COM | 74065P101 |
| — | Verve Therapeutics, Inc. | 1,691,530 | $7.73M | 0.1% | $52.72 | — | COM | 92539P101 |
| RCKT | Rocket Pharmaceuticals, Inc. | 1,097,079 | $7.318M | 0.1% | $10.34 | -4.4% | COM | 77313F106 |
| XNCR | Xencor, Inc. | 670,431 | $7.133M | 0.1% | $21.77 | -24.1% | COM | 98401F105 |
| DYN | Dyne Therapeutics, Inc. | 672,096 | $7.03M | 0.1% | $26.33 | -45.7% | COM | 26818M108 |
| KALA | KALA BIO, Inc. | 1,201,894 | $6.887M | 0.1% | $7.72 | -2.0% | COM | 483119202 |
| DSGN | Design Therapeutics, Inc. | 1,743,725 | $6.731M | 0.1% | $12.06 | -60.4% | COM | 25056L103 |
| GPCR | Structure Therapeutics Inc. | 361,565 | $6.259M | 0.1% | $31.09 | — | SPONSORED ADS | 86366E106 |
| TSHA | Taysha Gene Therapies, Inc. | 4,004,756 | $5.567M | 0.1% | $1.91 | -12.6% | COM SHS | 877619106 |
| — | Regulus Therapeutics Inc. | 2,694,044 | $4.715M | 0.1% | $1.75 | — | COM | 75915K309 |
| — | IGM Biosciences, Inc. | 4,095,257 | $4.71M | 0.1% | $15.73 | — | COM | 449585108 |
| NTLA | Intellia Therapeutics, Inc. | 644,116 | $4.58M | 0.1% | $15.61 | -35.3% | COM | 45826J105 |
| CLDX | Celldex Therapeutics, Inc. | 247,644 | $4.495M | 0.0% | $29.41 | -24.0% | COM | 15117B202 |
| SION | Sionna Therapeutics, Inc. | 400,000 | $4.184M | 0.0% | $16.34 | 0.0% | COM | 829401108 |
| BNTX | BioNTech SE | 45,031 | $4.101M | 0.0% | $113.95 | — | SPONSORED ADS | 09075V102 |
| TCRX | TScan Therapeutics, Inc. | 2,784,792 | $3.843M | 0.0% | $6.08 | -64.4% | COM | 89854M101 |
| IRON | Disc Medicine, Inc. | 77,050 | $3.825M | 0.0% | $57.84 | -3.9% | COM | 254604101 |
| VIR | Vir Biotechnology, Inc. | 542,539 | $3.516M | 0.0% | $7.89 | +12.7% | COM | 92764N102 |
| SANA | Sana Biotechnology, Inc. | 2,030,949 | $3.412M | 0.0% | $4.55 | -38.6% | COM | 799566104 |
| SGMT | Sagimet Biosciences Inc. | 952,996 | $3.107M | 0.0% | $9.53 | -56.0% | COM SER A | 786700104 |
| RLAY | Relay Therapeutics, Inc. | 1,160,117 | $3.04M | 0.0% | $13.78 | -71.6% | COM | 75943R102 |
| WVE | Wave Life Sciences Ltd. | 344,063 | $2.78M | 0.0% | $5.98 | +83.0% | SHS | Y95308105 |
| FATE | Fate Therapeutics, Inc. | 3,258,402 | $2.574M | 0.0% | $5.24 | -76.6% | COM | 31189P102 |
| SKYE | Skye Bioscience, Inc. | 1,450,638 | $2.307M | 0.0% | $7.74 | -64.7% | COM | 83086J200 |
| TARA | Protara Therapeutics, Inc. | 536,832 | $2.287M | 0.0% | $13.35 | -66.5% | COM STK | 74365U107 |
| ELVN | Enliven Therapeutics, Inc. | 114,833 | $2.26M | 0.0% | $15.34 | +40.3% | COM | 29337E102 |
| CTNM | Contineum Therapeutics, Inc. | 312,500 | $2.181M | 0.0% | $16.10 | -43.5% | CL A | 21217B100 |
| PRME | Prime Medicine, Inc. | 1,028,466 | $2.047M | 0.0% | $18.06 | -85.9% | COM | 74168J101 |
| TECX | Tectonic Therapeutic, Inc. | 100,000 | $1.771M | 0.0% | $32.59 | 0.0% | COM | 878972108 |
| VTVT | vTv Therapeutics, Inc. | 97,314 | $1.685M | 0.0% | $12.72 | +31.3% | CL A | 918385204 |
| CMPX | Compass Therapeutics, Inc. | 547,498 | $1.04M | 0.0% | $3.99 | -33.3% | COM | 20454B104 |
| NMRA | Neumora Therapeutics, Inc. | 1,034,600 | $1.035M | 0.0% | $13.91 | -87.7% | COM | 640979100 |
| HOOK | HOOKIPA Pharma Inc. | 812,814 | $878K | 0.0% | $7.93 | -79.2% | COM | 43906K209 |
| — | Generation Bio Co. | 1,944,945 | $788K | 0.0% | $2.93 | — | COM | 37148K100 |
| ALGS | Aligos Therapeutics, Inc. | 83,055 | $685K | 0.0% | $12.44 | +76.2% | COM | 01626L204 |
| CYPH | Leap Therapeutics, Inc. | 404,744 | $123K | 0.0% | $5.02 | -78.1% | COM | 52187K200 |
| IPSC | Century Therapeutics, Inc. | 241,684 | $115K | 0.0% | $9.79 | -92.3% | COM | 15673T100 |
| TYRA | Tyra Biosciences, Inc. | 10,607 | $98,645 | 0.0% | $12.95 | -0.0% | COM | 90240B106 |
| ACRV | Acrivon Therapeutics, Inc. | 22,809 | $46,302 | 0.0% | $4.64 | +16.0% | COMMON STOCK | 004890109 |
| SRZNW | Surrozen, Inc. | 833,333 | $25,000 | 0.0% | $1.14 | — | W EXP 8/11/2026 | 86889P117 |
| OPTEY | Opthea Limited | 2,087,320 | $0 | 0.0% | $11.12 | — | SPONSORED ADS | 68386J208 |