Location: New York, NY
CIK: 0001263508 · Show all filings
Period: Q2 2025 (← Previous) (Next →)
Filing Date: Aug 14, 2025
Total Value: $10.31B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| ONC | BeOne Medicines Ltd. | 8,799,053 | $2.13B | 20.7% | $136.93 | — | SPONSORED ADS | 07725L102 |
| INCY | Incyte Corporation | 30,743,275 | $2.094B | 20.3% | $72.80 | -13.0% | COM | 45337C102 |
| ACAD | ACADIA Pharmaceuticals Inc. | 42,896,690 | $925M | 9.0% | $18.93 | -1.8% | COM | 004225108 |
| INSM | Insmed Incorporated | 7,712,900 | $776M | 7.5% | $57.51 | +33.0% | COM PAR $.01 | 457669307 |
| SMMT | Summit Therapeutics Inc. | 33,722,974 | $718M | 7.0% | $10.51 | +117.1% | COM | 86627T108 |
| MDGL | Madrigal Pharmaceuticals, Inc. | 1,976,018 | $598M | 5.8% | $119.77 | +148.8% | COM | 558868105 |
| RYTM | Rhythm Pharmaceuticals, Inc. | 5,604,483 | $354M | 3.4% | $23.49 | +160.7% | COM | 76243J105 |
| RVMD | Revolution Medicines, Inc. | 9,364,972 | $345M | 3.3% | $29.36 | +30.9% | COM | 76155X100 |
| KYMR | Kymera Therapeutics, Inc. | 6,651,429 | $290M | 2.8% | $28.76 | +19.7% | COM | 501575104 |
| ALKS | Alkermes plc | 6,410,603 | $183M | 1.8% | $26.48 | +12.4% | SHS | G01767105 |
| REPL | Replimune Group, Inc. | 11,045,336 | $103M | 1.0% | $14.45 | -39.6% | COM | 76029N106 |
| RARE | Ultragenyx Pharmaceutical Inc. | 2,772,692 | $101M | 1.0% | $52.13 | -30.8% | COM | 90400D108 |
| EWTX | Edgewise Therapeutics, Inc. | 7,305,940 | $95.78M | 0.9% | $14.29 | +0.9% | COM | 28036F105 |
| ABCL | AbCellera Biologics Inc. | 27,525,640 | $94.41M | 0.9% | $21.02 | -88.2% | COM | 00288U106 |
| IMVT | Immunovant, Inc. | 5,457,881 | $87.33M | 0.8% | $22.96 | -34.1% | COM | 45258J102 |
| GRAL | GRAIL, Inc. | 1,630,125 | $83.82M | 0.8% | $16.26 | +122.6% | COM | 384747101 |
| KNSA | Kiniksa Pharmaceuticals International, plc | 2,824,669 | $78.16M | 0.8% | $18.73 | +35.9% | ORD SHS CL A | G52694109 |
| BCYC | Bicycle Therapeutics plc | 10,885,357 | $75.65M | 0.7% | $20.78 | — | SPONSORED ADS | 088786108 |
| IMCR | Immunocore Holdings plc | 2,322,656 | $72.88M | 0.7% | $38.09 | — | ADS | 45258D105 |
| CELC | Celcuity Inc. | 5,450,445 | $72.76M | 0.7% | $12.68 | -14.1% | COM | 15102K100 |
| KOD | Kodiak Sciences Inc. | 17,310,490 | $64.57M | 0.6% | $30.30 | -88.3% | COM | 50015M109 |
| IMTX | Immatics N.V. | 10,168,901 | $54.71M | 0.5% | $9.00 | -44.9% | SHS | N44445109 |
| STOK | Stoke Therapeutics, Inc. | 4,633,838 | $52.59M | 0.5% | $9.30 | +2.1% | COM | 86150R107 |
| DNLI | Denali Therapeutics Inc. | 3,731,695 | $52.21M | 0.5% | $23.78 | -40.8% | COM | 24823R105 |
| GPCR | Structure Therapeutics Inc. | 2,508,767 | $52.03M | 0.5% | $22.23 | — | SPONSORED ADS | 86366E106 |
| IDYA | IDEAYA Biosciences, Inc. | 2,118,728 | $44.54M | 0.4% | $16.90 | +13.5% | COM | 45166A102 |
| NRIX | Nurix Therapeutics, Inc. | 3,882,125 | $44.22M | 0.4% | $22.27 | -51.5% | COM | 67080M103 |
| ROIV | Roivant Sciences Ltd. | 3,767,773 | $42.46M | 0.4% | $9.71 | +11.6% | SHS | G76279101 |
| BNTX | BioNTech SE | 368,923 | $39.28M | 0.4% | $107.38 | — | SPONSORED ADS | 09075V102 |
| TRDA | Entrada Therapeutics, Inc. | 4,865,819 | $32.7M | 0.3% | $16.96 | — | COM | 29384C108 |
| — | Merus N.V. | 574,377 | $30.21M | 0.3% | $52.94 | — | COM | N5749R100 |
| PRAX | Praxis Precision Medicines, Inc. | 689,488 | $28.99M | 0.3% | $44.22 | -13.9% | COM | 74006W207 |
| NTLA | Intellia Therapeutics, Inc. | 2,675,674 | $25.1M | 0.2% | $9.99 | -17.8% | COM | 45826J105 |
| VRDN | Viridian Therapeutics, Inc. | 1,744,406 | $24.39M | 0.2% | $13.57 | 0.0% | COM | 92790C104 |
| GLUE | Monte Rosa Therapeutics, Inc. | 4,916,095 | $22.17M | 0.2% | $6.49 | -31.3% | COM | 61225M102 |
| — | Verona Pharma plc | 223,843 | $21.17M | 0.2% | $63.49 | — | SPONSORED ADS | 925050106 |
| PCVX | Vaxcyte, Inc. | 640,885 | $20.84M | 0.2% | $76.85 | -57.3% | COM | 92243G108 |
| ARGX | argenx SE | 37,760 | $20.81M | 0.2% | $79.01 | — | SPONSORED ADR | 04016X101 |
| — | Verve Therapeutics, Inc. | 1,691,530 | $19M | 0.2% | $52.72 | — | COM | 92539P101 |
| CERS | Cerus Corporation | 12,883,844 | $18.17M | 0.2% | $4.19 | -68.1% | COM | 157085101 |
| IRON | Disc Medicine, Inc. | 337,050 | $17.85M | 0.2% | $49.46 | -5.0% | COM | 254604101 |
| — | Akero Therapeutics, Inc. | 324,630 | $17.32M | 0.2% | $32.79 | — | COM | 00973Y108 |
| — | Blueprint Medicines Corporation | 125,538 | $16.09M | 0.2% | $128.18 | — | COM | 09627Y109 |
| SERA | Sera Prognostics, Inc. | 5,498,170 | $15.23M | 0.1% | $3.09 | -20.0% | CLASS A COM | 81749D107 |
| ARWR | Arrowhead Pharmaceuticals, Inc. | 939,174 | $14.84M | 0.1% | $14.35 | 0.0% | COM | 04280A100 |
| NGNE | Neurogene Inc. | 991,691 | $14.83M | 0.1% | $19.35 | -18.9% | COM | 64135M105 |
| DNTH | Dianthus Therapeutics, Inc. | 789,759 | $14.71M | 0.1% | $18.76 | 0.0% | COM | 252828108 |
| CLDX | Celldex Therapeutics, Inc. | 665,370 | $13.54M | 0.1% | $23.17 | -16.0% | COM | 15117B202 |
| DBVT | DBV Technologies S.A. | 1,461,425 | $13.39M | 0.1% | $3.09 | — | SPONSORED ADS | 23306J309 |
| XENE | Xenon Pharmaceuticals Inc. | 370,208 | $11.59M | 0.1% | $19.37 | +68.4% | COM | 98420N105 |
| — | Cidara Therapeutics, Inc. | 227,272 | $11.07M | 0.1% | $48.71 | — | COM | 171757206 |
| ACLX | Arcellx, Inc. | 166,825 | $10.99M | 0.1% | $62.26 | 0.0% | COMMON STOCK | 03940C100 |
| NUVL | Nuvalent, Inc. | 143,937 | $10.98M | 0.1% | $73.17 | 0.0% | COM | 670703107 |
| SYRE | Spyre Therapeutics, Inc. | 626,703 | $9.382M | 0.1% | $14.80 | 0.0% | COM | 00773J202 |
| TSHA | Taysha Gene Therapies, Inc. | 4,004,756 | $9.251M | 0.1% | $1.91 | +13.4% | COM SHS | 877619106 |
| PRLD | Prelude Therapeutics Inc. | 10,123,824 | $8.194M | 0.1% | $28.24 | -96.9% | COM | 74065P101 |
| CRNX | Crinetics Pharmaceuticals, Inc. | 280,000 | $8.053M | 0.1% | $30.88 | 0.0% | COM | 22663K107 |
| CTMX | CytomX Therapeutics, Inc. | 3,484,226 | $7.909M | 0.1% | $1.61 | 0.0% | COM | 23284F105 |
| SGMT | Sagimet Biosciences Inc. | 952,996 | $7.262M | 0.1% | $9.53 | -55.7% | COM SER A | 786700104 |
| SION | Sionna Therapeutics, Inc. | 400,000 | $6.94M | 0.1% | $16.34 | -19.8% | COM | 829401108 |
| AGIO | Agios Pharmaceuticals, Inc. | 189,866 | $6.315M | 0.1% | $30.31 | 0.0% | COM | 00847X104 |
| RAPP | Rapport Therapeutics, Inc. | 550,090 | $6.255M | 0.1% | $10.61 | 0.0% | COM | 75383L102 |
| SKYE | Skye Bioscience, Inc. | 1,450,638 | $6.064M | 0.1% | $7.74 | -73.3% | COM | 83086J200 |
| DSGN | Design Therapeutics, Inc. | 1,712,882 | $5.772M | 0.1% | $12.06 | -69.0% | COM | 25056L103 |
| KALA | KALA BIO, Inc. | 1,201,894 | $5.721M | 0.1% | $7.72 | -49.5% | COM | 483119202 |
| SANA | Sana Biotechnology, Inc. | 2,030,949 | $5.544M | 0.1% | $4.55 | -54.7% | COM | 799566104 |
| XNCR | Xencor, Inc. | 670,431 | $5.27M | 0.1% | $21.77 | -58.8% | COM | 98401F105 |
| ALMS | Alumis Inc. | 1,562,500 | $4.688M | 0.0% | $13.30 | -64.5% | COM | 022307102 |
| — | IGM Biosciences, Inc. | 4,096,210 | $4.588M | 0.0% | $15.73 | — | COM | 449585108 |
| TCRX | TScan Therapeutics, Inc. | 2,784,792 | $4.038M | 0.0% | $6.08 | -76.2% | COM | 89854M101 |
| RLAY | Relay Therapeutics, Inc. | 1,160,117 | $4.014M | 0.0% | $13.78 | -78.4% | COM | 75943R102 |
| FATE | Fate Therapeutics, Inc. | 2,485,018 | $2.783M | 0.0% | $5.24 | -77.8% | COM | 31189P102 |
| VIR | Vir Biotechnology, Inc. | 542,539 | $2.734M | 0.0% | $7.89 | -32.0% | COM | 92764N102 |
| ELVN | Enliven Therapeutics, Inc. | 114,833 | $2.304M | 0.0% | $15.34 | +23.4% | COM | 29337E102 |
| WVE | Wave Life Sciences Ltd. | 344,063 | $2.236M | 0.0% | $5.98 | +10.5% | SHS | Y95308105 |
| TECX | Tectonic Therapeutic, Inc. | 100,000 | $1.987M | 0.0% | $32.59 | -37.8% | COM | 878972108 |
| CADL | Candel Therapeutics, Inc. | 355,112 | $1.797M | 0.0% | $5.91 | -12.9% | COM | 137404109 |
| TARA | Protara Therapeutics, Inc. | 536,832 | $1.627M | 0.0% | $13.35 | -74.2% | COM STK | 74365U107 |
| VTVT | vTv Therapeutics, Inc. | 97,314 | $1.46M | 0.0% | $12.72 | +44.1% | CL A | 918385204 |
| RCKT | Rocket Pharmaceuticals, Inc. | 552,079 | $1.353M | 0.0% | $10.34 | -51.0% | COM | 77313F106 |
| CTNM | Contineum Therapeutics, Inc. | 312,500 | $1.241M | 0.0% | $16.10 | -73.0% | CL A | 21217B100 |
| HOOK | HOOKIPA Pharma Inc. | 812,814 | $1.02M | 0.0% | $7.93 | -84.4% | COM | 43906K209 |
| NMRA | Neumora Therapeutics, Inc. | 1,034,600 | $759K | 0.0% | $13.91 | -94.6% | COM | 640979100 |
| — | Generation Bio Co. | 1,944,945 | $623K | 0.0% | $2.93 | — | COM | 37148K100 |
| ALGS | Aligos Therapeutics, Inc. | 83,055 | $599K | 0.0% | $12.44 | -51.9% | COM | 01626L204 |
| TYRA | Tyra Biosciences, Inc. | 10,607 | $102K | 0.0% | $12.95 | -26.6% | COM | 90240B106 |
| ACRV | Acrivon Therapeutics, Inc. | 22,809 | $27,143 | 0.0% | $4.64 | -70.4% | COMMON STOCK | 004890109 |
| SRZNW | Surrozen, Inc. | 833,333 | $15,083 | 0.0% | $1.14 | — | W EXP 8/11/2026 | 86889P117 |
| OPTEY | Opthea Limited | 2,087,320 | $0 | 0.0% | $11.12 | — | SPONSORED ADS | 68386J208 |