Location: New York, NY
CIK: 0001263508 · Show all filings
Period: Q2 2015 (← Previous) (Next →)
Filing Date: Aug 14, 2015
Total Value: $11.4B (82.5% shares, 17.5% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| INCY | Incyte Corporation | 14,865,559 | $1.549B | 13.6% | $21.85 | +373.8% | COM | 45337C102 |
| — | Seattle Genetics, Inc. | 30,870,262 | $1.494B | 13.1% | $33.57 | — | COM | 812578102 |
| — | Alexion Pharmaceuticals, Inc. | 6,542,599 | $1.183B | 10.4% | $180.77 | — | COM | 015351109 |
| ABBV | AbbVie Inc. | 14,373,538 | $966M | 8.5% | $42.33 | 0.0% | COM | 00287Y109 |
| ACAD | ACADIA Pharmaceuticals Inc. | 20,481,442 | $858M | 7.5% | $14.07 | +175.1% | COM | 004225108 |
| — | Incyte Corporation Notes 1.25% 11/15/2020 144A | 274,500,000 | $568M | 5.0% | $1.21 | — | CONV BONDS | 45337CAL6 |
| BMRN | BioMarin Pharmaceutical Inc. | 4,095,247 | $560M | 4.9% | $75.89 | +63.3% | COM | 09061G101 |
| — | Incyte Corporation Notes 0.375% 11/15/2018 144A | 259,000,000 | $530M | 4.6% | $1.20 | — | CONV BONDS | 45337CAK8 |
| — | Incyte Corporation Notes 4.75% 10/1/2015 144A | 40,446,000 | $479M | 4.2% | $6.08 | — | CONV BONDS | 45337CAJ1 |
| — | Genomic Health Inc. | 13,657,598 | $380M | 3.3% | $31.71 | — | COM | 37244C101 |
| — | Anacor Pharmaceuticals, Inc. | 3,625,498 | $281M | 2.5% | $19.02 | — | COM | 032420101 |
| — | Dyax Corp. | 7,926,630 | $210M | 1.8% | $13.14 | — | COM | 26746E103 |
| BCRX | BioCryst Pharmaceuticals, Inc. | 11,577,299 | $173M | 1.5% | $6.26 | +81.6% | COM | 09058V103 |
| — | BioMarin Pharmaceutical Inc. Notes 1.875% 4/23/2017 | 22,379,000 | $150M | 1.3% | $2.76 | — | CONV BONDS | 09061GAD3 |
| — | Gilead, Inc. 1.625% 5/1/16 | 20,944,000 | $108M | 0.9% | $2.26 | — | CONV BONDS | 375558AP8 |
| — | Invitae Corporation | 6,554,967 | $97.54M | 0.9% | $16.76 | — | COM | 46185L103 |
| — | Bellicum Pharmaceuticals, Inc. | 4,190,594 | $89.13M | 0.8% | $23.04 | — | COM | 079481107 |
| — | Mirati Therapeutics, Inc. | 2,805,074 | $88.28M | 0.8% | $17.51 | — | COM | 60468T105 |
| HRTX | Heron Therapeutics, Inc. | 2,807,784 | $87.49M | 0.8% | $12.94 | +45.4% | COM | 427746102 |
| — | Spark Therapeutics, Inc. | 1,262,382 | $76.08M | 0.7% | $77.50 | — | COM | 84652J103 |
| — | Medivation, Inc. 2.625% 4/1/17 | 33,889,000 | $75.01M | 0.7% | $1.27 | — | CONV BONDS | 58501NAA9 |
| CERS | Cerus Corporation | 13,553,275 | $70.34M | 0.6% | $4.68 | +1.1% | COM | 157085101 |
| — | Acorda Therapeutics, Inc. Notes 1.75% 6/15/2021 | 59,583,000 | $60.05M | 0.5% | $1.04 | — | CONV BONDS | 00484MAA4 |
| — | XOMA Corporation | 14,683,513 | $56.97M | 0.5% | $3.73 | — | COM | 98419J107 |
| — | DBV Technologies S.A. | 1,862,019 | $55.45M | 0.5% | $27.61 | — | SPONSORED ADR | 23306J101 |
| — | Versartis, Inc. | 3,436,585 | $52.3M | 0.5% | $22.68 | — | COM | 92529L102 |
| — | Alder Biopharmaceuticals Inc. | 891,688 | $47.23M | 0.4% | $27.68 | — | COM | 014339105 |
| HALO | Halozyme Therapeutics, Inc. | 1,931,057 | $43.6M | 0.4% | $6.50 | +170.5% | COM | 40637H109 |
| — | aTyr Pharma Inc. | 2,335,125 | $43.25M | 0.4% | $18.52 | — | COM | 002120103 |
| — | XenoPort, Inc. | 6,508,622 | $39.9M | 0.3% | $5.27 | — | COM | 98411C100 |
| — | Array BioPharma Inc. | 5,482,505 | $39.53M | 0.3% | $6.65 | — | COM | 04269X105 |
| INSM | Insmed, Inc. | 1,583,490 | $38.67M | 0.3% | $14.99 | +51.5% | COM | 457669307 |
| SGMO | Sangamo BioSciences, Inc. | 3,230,932 | $35.83M | 0.3% | $13.18 | -2.1% | COM | 800677106 |
| — | ImmunoGen, Inc. | 2,320,424 | $33.37M | 0.3% | $12.04 | — | COM | 45253H101 |
| TGTX | TG Therapeutics, Inc. | 2,003,991 | $33.25M | 0.3% | $4.61 | +243.8% | COM | 88322Q108 |
| — | Progenics Pharmaceuticals, Inc. | 4,350,808 | $32.46M | 0.3% | $4.44 | — | COM | 743187106 |
| CPRX | Catalyst Pharmaceuticals, Inc. | 7,335,692 | $30.3M | 0.3% | $2.58 | +54.4% | COM | 14888U101 |
| GILD | Gilead Sciences, Inc. | 249,995 | $29.27M | 0.3% | $36.21 | +109.8% | COM | 375558103 |
| — | Kythera Biopharmaceuticals, Inc. | 387,741 | $29.2M | 0.3% | $40.81 | — | COM | 501570105 |
| NBIX | Neurocrine Biosciences, Inc. | 542,236 | $25.9M | 0.2% | $16.53 | +156.5% | COM | 64125C109 |
| — | Idera Pharmaceuticals, Inc. | 6,970,902 | $25.86M | 0.2% | $3.05 | — | COM | 45168K306 |
| — | bluebird bio, Inc. | 151,105 | $25.44M | 0.2% | $29.38 | — | COM | 09609G100 |
| — | Derma Sciences, Inc. | 3,457,841 | $24.76M | 0.2% | $12.84 | — | COM | 249827502 |
| — | Acorda Therapeutics, Inc. | 738,916 | $24.63M | 0.2% | $37.91 | — | COM | 00484M106 |
| — | Novavax, Inc. | 1,945,687 | $21.68M | 0.2% | $5.05 | — | COM | 670002104 |
| — | Foamix Pharmaceuticals Ltd. | 2,046,967 | $20.98M | 0.2% | $7.46 | — | SHS | M46135105 |
| XNCR | Xencor, Inc. | 872,072 | $19.16M | 0.2% | $11.07 | +54.0% | COM | 98401F105 |
| GLPG | Galapagos NV | 369,276 | $19.02M | 0.2% | $51.50 | — | SPONSORED ADR | 36315X101 |
| — | BioMarin Pharmaceutical Inc. Notes 0.75% 10/15/2018 | 12,228,000 | $18.94M | 0.2% | $1.06 | — | CONV BONDS | 09061GAE1 |
| — | Clovis Oncology, Inc. | 202,630 | $17.81M | 0.2% | $56.00 | — | COM | 189464100 |
| OMER | Omeros Corporation | 964,621 | $17.35M | 0.2% | $12.37 | +74.4% | COM | 682143102 |
| — | Zogenix, Inc. | 10,028,564 | $16.85M | 0.1% | $1.79 | — | COM | 98978L105 |
| — | Lion Biotechnologies, Inc. | 1,817,429 | $16.67M | 0.1% | $11.31 | — | COM | 53619R102 |
| PRQR | ProQR Therapeutics N.V. | 988,299 | $16.48M | 0.1% | $17.70 | +6.4% | SHS | N71542109 |
| — | Repros Therapeutics Inc. | 1,955,944 | $13.98M | 0.1% | $18.45 | — | COM | 76028H209 |
| — | Achillion Pharmaceuticals, Inc. | 1,523,739 | $13.5M | 0.1% | $8.76 | — | COM | 00448Q201 |
| RARE | Ultragenyx Pharmaceuticals | 123,894 | $12.69M | 0.1% | $51.09 | +52.0% | COM | 90400D108 |
| — | Threshold Pharmaceuticals, Inc. | 2,925,519 | $11.82M | 0.1% | $4.38 | — | COM | 885807206 |
| — | Alcobra Ltd. | 1,789,871 | $11.71M | 0.1% | $5.32 | — | SHS | M2239P109 |
| MGNX | MacroGenics, Inc. | 305,043 | $11.58M | 0.1% | $22.61 | +45.4% | COM | 556099109 |
| AGIO | Agios Pharmaceuticals, Inc. | 100,000 | $11.11M | 0.1% | $27.47 | +292.1% | COM | 00847X104 |
| — | La Jolla Pharmaceutical Company | 412,008 | $10.1M | 0.1% | $10.24 | — | COM | 503459604 |
| — | Zafgen, Inc. | 287,677 | $9.962M | 0.1% | $36.27 | — | COM | 98885E103 |
| — | Osiris Therapeutics, Inc. | 499,193 | $9.714M | 0.1% | $16.34 | — | COM | 68827R108 |
| — | Sunesis Pharmaceuticals, Inc. | 3,200,000 | $9.632M | 0.1% | $2.55 | — | COM | 867328601 |
| — | Ignyta, Inc. | 571,000 | $8.616M | 0.1% | $8.30 | — | COM | 451731103 |
| — | Aquinox Pharmaceuticals, Inc. | 1,197,366 | $8.31M | 0.1% | $12.73 | — | COM | 03842B101 |
| — | Sage Therapeutics, Inc. | 105,000 | $7.665M | 0.1% | $43.36 | — | COM | 78667J108 |
| LGND | Ligand Pharmaceuticals Incorporated | 73,386 | $7.405M | 0.1% | $41.68 | +30.9% | COM | 53220K504 |
| — | Concert Pharmaceuticals, Inc. | 495,908 | $7.384M | 0.1% | $10.71 | — | COM | 206022105 |
| — | Arrowhead Research Corp. | 1,009,509 | $7.218M | 0.1% | $9.76 | — | COM | 042797209 |
| — | Karyopharm Therapeutics Inc. | 216,990 | $5.904M | 0.1% | $31.09 | — | COM | 48576U106 |
| — | Epizyme, Inc. | 232,481 | $5.58M | 0.0% | $21.12 | — | COM | 29428V104 |
| — | Amarin Corporation plc | 2,205,710 | $5.426M | 0.0% | $2.34 | — | SPONSORED ADR | 023111206 |
| — | Affimed N.V. | 400,000 | $5.388M | 0.0% | $6.30 | — | COM | N01045108 |
| — | Chimerix, Inc. | 115,216 | $5.323M | 0.0% | $40.26 | — | COM | 16934W106 |
| — | Aerie Pharmaceuticals, Inc. | 299,356 | $5.284M | 0.0% | $17.96 | — | COM | 00771V108 |
| VNDA | Vanda Pharmaceuticals Inc. | 409,881 | $5.201M | 0.0% | $7.51 | +43.5% | COM | 921659108 |
| — | Seres Therapeutics, Inc. | 125,000 | $5.188M | 0.0% | $41.50 | — | COM | 81750R102 |
| — | CytRx Corporation | 1,319,989 | $4.91M | 0.0% | $3.49 | — | COM | 232828509 |
| — | Assembly Biosciences, Inc. | 250,000 | $4.815M | 0.0% | $13.24 | — | COM | 045396108 |
| — | Receptos, Inc. | 23,900 | $4.542M | 0.0% | $19.89 | — | COM | 756207106 |
| — | Juno Therapeutics, Inc. | 80,000 | $4.266M | 0.0% | $52.22 | — | COM | 48205A109 |
| — | Stemline Therapeutics, Inc. | 333,497 | $3.925M | 0.0% | $23.84 | — | COM | 85858C107 |
| — | NeuroDerm Ltd. | 250,000 | $3.838M | 0.0% | $14.04 | — | ORD SHS | M74231107 |
| — | Array BioPharma Inc. Notes 3.0% 6/1/2020 | 3,000,000 | $3.78M | 0.0% | $1.25 | — | CONV BONDS | 04269XAA3 |
| — | Curis, Inc. | 1,077,663 | $3.567M | 0.0% | $3.31 | — | COM | 231269101 |
| ENTA | Enanta Pharmaceuticals, Inc. | 75,357 | $3.39M | 0.0% | $19.50 | +99.5% | COM | 29251M106 |
| — | Intra-Cellular Therapies, Inc. | 104,166 | $3.328M | 0.0% | $23.88 | — | COM | 46116X101 |
| — | Isis Pharmaceuticals, Inc. | 57,140 | $3.288M | 0.0% | $26.87 | — | COM | 464330109 |
| — | Proteon Therapeutics, Inc. | 176,762 | $3.157M | 0.0% | $10.56 | — | COM | 74371L109 |
| — | Immune Design Corp. | 148,937 | $3.076M | 0.0% | $20.65 | — | COM | 45252L103 |
| — | Bellerophon Therapeutics, Inc. | 350,000 | $2.776M | 0.0% | $9.18 | — | COM | 078771102 |
| — | Vitae Pharmaceuticals, Inc. | 187,597 | $2.701M | 0.0% | $11.71 | — | COM | 92847N103 |
| — | Protalix BioTherapeutics, Inc. Notes 4.5% 9/15/18 | 3,423,000 | $2.606M | 0.0% | $0.76 | — | CONV BONDS | 74365AAB7 |
| — | Discovery Laboratories, Inc. | 3,569,643 | $2.427M | 0.0% | $1.95 | — | COM | 254668403 |
| — | Marinus Pharmaceuticals, Inc. | 200,000 | $2.32M | 0.0% | $6.47 | — | COM | 56854Q101 |
| — | Mast Therapeutics, Inc. | 4,707,464 | $2.307M | 0.0% | $0.56 | — | COM | 576314108 |
| — | ZIOPHARM Oncology, Inc. | 189,259 | $2.271M | 0.0% | $2.11 | — | COM | 98973P101 |
| — | Tekmira Pharmaceuticals Corp. | 180,582 | $2.142M | 0.0% | $7.97 | — | COM | 87911B209 |
| AUPH | Aurinia Pharmaceuticals Inc. | 711,499 | $2.13M | 0.0% | $3.55 | +4.5% | COM | 05156V102 |
| IRWD | Ironwood Pharmaceuticals, Inc. | 169,163 | $2.04M | 0.0% | $11.63 | -0.1% | COM | 46333X108 |
| — | Ophthotech Corporation | 35,649 | $1.856M | 0.0% | $32.35 | — | COM | 683745103 |
| ADAPY | Adaptimmune Therapeutics plc | 100,000 | $1.833M | 0.0% | $18.33 | — | SPONSORED ADR | 00653A107 |
| — | Palatin Technologies, Inc. | 2,050,000 | $1.825M | 0.0% | $0.73 | — | COM | 696077403 |
| CLLS | Cellectis S.A. | 50,000 | $1.804M | 0.0% | $34.58 | — | SPONSORED ADR | 15117K103 |
| — | Loxo Oncology, Inc. | 100,000 | $1.803M | 0.0% | $13.13 | — | COM | 548862101 |
| — | Ritter Pharmaceuticals, Inc. | 400,000 | $1.78M | 0.0% | $4.45 | — | COM | 767836109 |
| ASND | Ascendis Pharma A/S | 100,000 | $1.768M | 0.0% | $17.35 | — | SPONSORED ADR | 04351P101 |
| — | Dermira, Inc. | 100,000 | $1.755M | 0.0% | $18.11 | — | COM | 24983L104 |
| — | Biota Pharmaceuticals, Inc. | 830,440 | $1.719M | 0.0% | $4.19 | — | COM | 090694100 |
| — | BioDelivery Sciences International, Inc. | 210,021 | $1.672M | 0.0% | $5.21 | — | COM | 09060J106 |
| — | MediWound Ltd. | 225,000 | $1.591M | 0.0% | $11.38 | — | ORD SHS | M68830104 |
| ALNY | Alnylam Pharmaceuticals, Inc. | 11,340 | $1.359M | 0.0% | $77.42 | +54.4% | COM | 02043Q107 |
| — | Tenax Therapeutics Inc. | 355,348 | $1.311M | 0.0% | $3.69 | — | COM | 88032L100 |
| ALDX | Aldeyra Therapeutics, Inc. | 142,000 | $1.102M | 0.0% | $10.20 | -15.5% | COM | 01438T106 |
| — | Ohr Pharmaceuticals, Inc. | 370,370 | $930K | 0.0% | $2.54 | — | COM | 67778H200 |
| — | Acceleron Pharma, Inc. | 28,765 | $910K | 0.0% | $39.60 | — | COM | 00434H108 |
| QURE | UniQure B.V. | 30,000 | $810K | 0.0% | $15.95 | +78.6% | SHS | N90064101 |
| — | Foundation Medicine, Inc. | 20,892 | $707K | 0.0% | $25.16 | — | COM | 350465100 |
| — | Achaogen, Inc. | 100,000 | $603K | 0.0% | $15.46 | — | COM | 004449104 |
| — | Five Prime Therapeutics, Inc. | 19,247 | $478K | 0.0% | $16.80 | — | COM | 33830X104 |
| — | ChemoCentryx, Inc. | 49,064 | $404K | 0.0% | $14.14 | — | COM | 16383L106 |
| — | Aptose Biosciences, Inc. | 33,397 | $170K | 0.0% | $5.91 | — | COM | 03835T200 |
| — | Cyclacel Pharmaceuticals, Inc. Pfd. Conv. Ex 6% | 13,253 | $85,000 | 0.0% | $7.20 | — | PFD CONV EX 6% | 23254L207 |
| — | BioTime, Inc. Rights | 20,084 | $23,000 | 0.0% | $1.07 | — | WARRANTS | 09066L162 |