RA CAPITAL MANAGEMENT, L.P. Diversified Active

CIK: 0001346824 · Show all filings

Period: Q4 2021 (← Previous) (Next →)

Filing Date: Feb 14, 2022

Total Value ($000): $5,671,942 (100.0% shares, 0.0% debt)

Holdings (97)

ASND ASCENDIS PHARMA A/S 17.9%
Value ($000) $1,018,110 Shares 7,567,900 Est. Cost $73.22 Unrealized —
NVAX NOVAVAX INC 5.3%
Value ($000) $300,131 Shares 2,097,794 Est. Cost $84.76 Unrealized +102.7%
— ITEOS THERAPEUTICS INC 3.6%
Value ($000) $205,668 Shares 4,417,259 Est. Cost $24.67 Unrealized —
TVTX TRAVERE THERAPEUTICS INC 3.1%
Value ($000) $174,272 Shares 5,614,428 Est. Cost $24.15 Unrealized +16.6%
JANX JANUX THERAPEUTICS INC 3.0%
Value ($000) $171,072 Shares 8,670,644 Est. Cost $22.27 Unrealized -5.9%
CTKB CYTEK BIOSCIENCES INC 2.8%
Value ($000) $156,787 Shares 9,607,028 Est. Cost $23.52 Unrealized -11.0%
— IMMUNOGEN INC 2.6%
Value ($000) $150,192 Shares 20,241,458 Est. Cost $5.55 Unrealized —
CLYM ELIEM THERAPEUTICS INC 2.4%
Value ($000) $137,558 Shares 13,150,849 Est. Cost $20.66 Unrealized -27.8%
— ICOSAVAX INC 2.3%
Value ($000) $132,231 Shares 5,779,347 Est. Cost $29.59 Unrealized —
— DICE THERAPEUTICS INC 2.3%
Value ($000) $131,838 Shares 5,208,911 Est. Cost $32.75 Unrealized —
— VOR BIOPHARMA INC 2.3%
Value ($000) $129,226 Shares 11,120,973 Est. Cost $43.10 Unrealized —
— FORMA THERAPEUTICS 2.3%
Value ($000) $128,146 Shares 9,011,651 Est. Cost $46.49 Unrealized —
TYRA TYRA BIOSCIENCES INC 1.8%
Value ($000) $101,817 Shares 7,236,454 Est. Cost $19.11 Unrealized +3.9%
PCVX VAXCYTE INC 1.8%
Value ($000) $100,881 Shares 4,240,464 Est. Cost $31.18 Unrealized -25.4%
MGNX MACROGENICS INC 1.7%
Value ($000) $97,963 Shares 6,103,594 Est. Cost $20.01 Unrealized -6.0%
— AEROVATE THERAPEUTICS INC 1.7%
Value ($000) $97,432 Shares 8,263,982 Est. Cost $22.83 Unrealized —
NKTX NKARTA INC 1.5%
Value ($000) $86,039 Shares 5,605,129 Est. Cost $29.47 Unrealized -41.8%
DAWN DAY ONE BIOPHARMACEUTICALS 1.5%
Value ($000) $83,670 Shares 4,965,588 Est. Cost $20.76 Unrealized -1.0%
— INSTIL BIO INC 1.5%
Value ($000) $83,339 Shares 4,870,793 Est. Cost $25.08 Unrealized —
— BELLUS HEALTH INC NEW 1.5%
Value ($000) $82,354 Shares 10,230,274 Est. Cost $8.05 Unrealized —
CLDX CELLDEX THERAPEUTICS INC NEW 1.2%
Value ($000) $69,737 Shares 1,804,795 Est. Cost $46.55 Unrealized -6.4%
TNYA TENAYA THERAPEUTICS INC 1.2%
Value ($000) $67,301 Shares 3,551,508 Est. Cost $21.49 Unrealized +1.4%
GHRS GH RESEARCH PLC 1.2%
Value ($000) $66,345 Shares 2,843,757 Est. Cost $20.42 Unrealized +7.6%
ABOS ACUMEN PHARMACEUTICALS INC 1.2%
Value ($000) $66,050 Shares 9,770,773 Est. Cost $16.64 Unrealized -33.9%
— 89BIO INC 1.1%
Value ($000) $64,903 Shares 4,965,769 Est. Cost $25.74 Unrealized —
— KINNATE BIOPHARMA INC 1.1%
Value ($000) $63,669 Shares 3,593,052 Est. Cost $39.78 Unrealized —
PHAT PHATHOM PHARMACEUTICALS INC 1.1%
Value ($000) $61,272 Shares 3,115,008 Est. Cost $25.67 Unrealized -8.3%
— MIRATI THERAPEUTICS INC 1.0%
Value ($000) $55,896 Shares 381,046 Est. Cost $146.69 Unrealized —
— ZOGENIX INC 1.0%
Value ($000) $54,173 Shares 3,333,700 Est. Cost $26.04 Unrealized —
— PARDES BIOSCIENCES INC 0.9%
Value ($000) $51,190 Shares 3,127,038 Est. Cost $16.37 Unrealized —
HOWL WEREWOLF THERAPEUTICS INC 0.9%
Value ($000) $51,116 Shares 4,291,881 Est. Cost $13.70 Unrealized +10.2%
— POINT BIOPHARMA GLOBAL INC 0.9%
Value ($000) $50,417 Shares 9,003,018 Est. Cost $7.66 Unrealized —
RYTM RHYTHM PHARMACEUTICALS INC 0.9%
Value ($000) $48,613 Shares 4,871,067 Est. Cost $24.79 Unrealized -54.7%
LIANY LIANBIO 0.8%
Value ($000) $47,155 Shares 7,655,015 Est. Cost $6.16 Unrealized —
DSGN DESIGN THERAPEUTICS INC 0.8%
Value ($000) $46,816 Shares 2,186,636 Est. Cost $31.14 Unrealized -44.9%
RCKT ROCKET PHARMACEUTICALS INC 0.8%
Value ($000) $45,999 Shares 2,107,149 Est. Cost $36.45 Unrealized -25.2%
RLMD RELMADA THERAPEUTICS 0.8%
Value ($000) $45,060 Shares 2,000,000 Est. Cost $22.24 Unrealized 0.0%
CCCC C4 THERAPEUTICS INC 0.8%
Value ($000) $44,358 Shares 1,377,569 Est. Cost $29.00 Unrealized +36.4%
TGTX TG THERAPEUTICS INC 0.7%
Value ($000) $41,993 Shares 2,210,145 Est. Cost $15.45 Unrealized +68.0%
EYPT EYEPOINT PHARMACEUTICALS 0.7%
Value ($000) $41,255 Shares 3,370,506 Est. Cost $11.52 Unrealized +16.8%
CNTA CENTESSA PHARMACEUTICALS PLC 0.7%
Value ($000) $40,278 Shares 3,577,094 Est. Cost $18.67 Unrealized —
EWTX EDGEWISE THERAPEUTICS INC 0.7%
Value ($000) $39,936 Shares 2,613,623 Est. Cost $32.43 Unrealized -44.5%
PMVP PMV PHARMACEUTICALS INC 0.7%
Value ($000) $39,507 Shares 1,710,265 Est. Cost $36.80 Unrealized -34.3%
— CYTEIR THERAPEUTICS INC 0.7%
Value ($000) $38,095 Shares 3,350,506 Est. Cost $21.28 Unrealized —
GERN GERON CORP 0.6%
Value ($000) $36,754 Shares 30,126,299 Est. Cost $1.49 Unrealized -4.2%
IVVD ADAGIO THERAPEUTICS INC 0.6%
Value ($000) $36,270 Shares 4,995,807 Est. Cost $37.11 Unrealized -29.9%
— CONNECT BIOPHARMA HLDGS LTD 0.6%
Value ($000) $36,004 Shares 6,991,003 Est. Cost $19.09 Unrealized —
RXST RXSIGHT INC 0.6%
Value ($000) $34,344 Shares 3,052,796 Est. Cost $13.76 Unrealized -12.7%
— VERONA PHARMA PLC 0.6%
Value ($000) $34,272 Shares 5,100,000 Est. Cost $6.24 Unrealized —
— GRAPHITE BIO INC 0.6%
Value ($000) $33,541 Shares 2,698,369 Est. Cost $30.73 Unrealized —
DYN DYNE THERAPEUTICS INC 0.6%
Value ($000) $33,352 Shares 2,805,045 Est. Cost $21.96 Unrealized -36.0%
XLO XILIO THERAPEUTICS INC 0.6%
Value ($000) $32,035 Shares 2,002,217 Est. Cost $17.03 Unrealized 0.0%
— SATSUMA PHARMACEUTICALS INC 0.5%
Value ($000) $26,614 Shares 5,914,252 Est. Cost $13.11 Unrealized —
KALV KALVISTA PHARMACEUTICALS INC 0.5%
Value ($000) $25,538 Shares 1,930,322 Est. Cost $26.18 Unrealized -39.2%
— ACHILLES THERAPEUTICS PLC 0.4%
Value ($000) $25,124 Shares 5,014,687 Est. Cost $11.66 Unrealized —
PYXS PYXIS ONCOLOGY INC 0.4%
Value ($000) $25,035 Shares 2,282,173 Est. Cost $11.45 Unrealized 0.0%
TNGX TANGO THERAPEUTICS INC 0.4%
Value ($000) $24,615 Shares 2,250,000 Est. Cost $11.99 Unrealized +0.3%
WVE WAVE LIFE SCIENCES LTD 0.4%
Value ($000) $24,414 Shares 7,775,207 Est. Cost $17.26 Unrealized -75.9%
— SOLID BIOSCIENCES INC 0.4%
Value ($000) $21,644 Shares 12,367,873 Est. Cost $7.59 Unrealized —
OLMA OLEMA PHARMACEUTICALS INC 0.4%
Value ($000) $20,128 Shares 2,150,404 Est. Cost $46.89 Unrealized -55.8%
— AKOUOS INC 0.3%
Value ($000) $19,391 Shares 2,281,249 Est. Cost $22.50 Unrealized —
RLAY RELAY THERAPEUTICS INC 0.3%
Value ($000) $16,861 Shares 549,055 Est. Cost $31.60 Unrealized 0.0%
— CHINOOK THERAPEUTICS 0.3%
Value ($000) $16,310 Shares 1,000,000 Est. Cost $16.31 Unrealized —
— SYNLOGIC INC 0.3%
Value ($000) $16,133 Shares 6,666,666 Est. Cost $3.05 Unrealized —
MIST MILESTONE PHARMACEUTICALS IN 0.3%
Value ($000) $14,715 Shares 2,246,503 Est. Cost $7.17 Unrealized -16.5%
— DA32 LIFE SCNCE 0.3%
Value ($000) $14,715 Shares 1,500,000 Est. Cost $9.83 Unrealized —
IPSC CENTURY THERAPEUTICS INC 0.3%
Value ($000) $14,498 Shares 914,094 Est. Cost $25.37 Unrealized -26.0%
LRMR LARIMAR THERAPEUTICS INC 0.3%
Value ($000) $14,400 Shares 1,334,610 Est. Cost $11.65 Unrealized -4.5%
BDTX BLACK DIAMOND THERAPEUTICS INC 0.2%
Value ($000) $13,804 Shares 2,589,904 Est. Cost $30.22 Unrealized -76.9%
— SCPHARMACEUTICALS 0.2%
Value ($000) $13,513 Shares 2,691,770 Est. Cost $10.74 Unrealized —
— KALA PHARMACEUTICALS INC 0.2%
Value ($000) $13,158 Shares 10,874,613 Est. Cost $10.65 Unrealized —
— ORCHARD THERAPEUTICS PLC 0.2%
Value ($000) $12,797 Shares 9,694,789 Est. Cost $10.43 Unrealized —
NAUT NAUTILUS 0.2%
Value ($000) $12,621 Shares 2,436,430 Est. Cost $10.83 Unrealized -50.6%
— BCLS ACQUISITION CORP 0.2%
Value ($000) $12,250 Shares 1,250,000 Est. Cost $11.14 Unrealized —
IOBT IO BIOTECH INC 0.2%
Value ($000) $11,890 Shares 1,857,755 Est. Cost $9.66 Unrealized 0.0%
— BOLT BIOTHERAPEUTICS INC 0.2%
Value ($000) $11,654 Shares 2,378,325 Est. Cost $32.91 Unrealized —
— OTONOMY INC 0.2%
Value ($000) $11,648 Shares 5,600,000 Est. Cost $2.03 Unrealized —
SPRY SILVERBACK THERAPEUTICS INC 0.2%
Value ($000) $11,603 Shares 1,742,186 Est. Cost $33.40 Unrealized -75.7%
— VERVE THERAPEUTICS INC 0.2%
Value ($000) $11,440 Shares 310,284 Est. Cost $60.25 Unrealized —
RNAM AVIDITY BIOSCIENCES INC 0.2%
Value ($000) $10,069 Shares 423,616 Est. Cost $21.74 Unrealized +9.9%
HLTHQ CUE HEALTH INC 0.2%
Value ($000) $10,058 Shares 750,000 Est. Cost $11.81 Unrealized —
— FRAZIER LIFESCIENCES ACQU CO 0.2%
Value ($000) $9,920 Shares 1,000,000 Est. Cost $10.38 Unrealized —
— ARYA SCIENCES ACQUISITN 0.2%
Value ($000) $9,700 Shares 1,000,000 Est. Cost $9.88 Unrealized —
— CONCERT PHARMACEUTICALS INC 0.2%
Value ($000) $9,556 Shares 3,033,603 Est. Cost $7.30 Unrealized —
— IKENA ONCOLOGY INC 0.2%
Value ($000) $9,405 Shares 750,000 Est. Cost $28.25 Unrealized —
COGT COGENT BIOSCIENCES INC 0.2%
Value ($000) $8,800 Shares 1,025,641 Est. Cost $10.99 Unrealized -20.9%
— PHASEBIO PHARMACEUTICALS INC 0.1%
Value ($000) $7,439 Shares 2,850,000 Est. Cost $3.46 Unrealized —
— 5 01 ACQUISITION CORP 0.1%
Value ($000) $7,388 Shares 750,000 Est. Cost $10.17 Unrealized —
— ASTRIA THERAPEUTICS INC 0.1%
Value ($000) $6,803 Shares 1,262,193 Est. Cost $8.84 Unrealized —
ENTX ENTERA BIO LTD 0.1%
Value ($000) $6,624 Shares 2,353,000 Est. Cost $3.70 Unrealized +1.4%
— HEALTH SCIENCES ACQ CORP 2 0.1%
Value ($000) $6,300 Shares 625,000 Est. Cost $11.00 Unrealized —
CMPX COMPASS THERAPEUTICS INC 0.1%
Value ($000) $5,863 Shares 1,849,518 Est. Cost $3.29 Unrealized 0.0%
TCRX TSCAN THERAPEUTICS INC 0.1%
Value ($000) $5,649 Shares 1,255,317 Est. Cost $9.27 Unrealized -22.1%
CGEM CULLINAN ONCOLOGY INC 0.1%
Value ($000) $5,401 Shares 350,000 Est. Cost $40.60 Unrealized -50.9%
BMEA BIOMEA FUSION INC 0.1%
Value ($000) $3,725 Shares 500,000 Est. Cost $17.65 Unrealized -40.1%
CVRX CVRX INC 0.1%
Value ($000) $3,363 Shares 275,000 Est. Cost $28.00 Unrealized -48.2%
— SYROS PHARMACEUTICALS INC 0.1%
Value ($000) $2,934 Shares 900,000 Est. Cost $7.48 Unrealized —