Location: Boston, MA
CIK: 0001346824 · Show all filings
Period: Q1 2024 (← Previous) (Next →)
Filing Date: May 17, 2024
Total Value: $7.86B
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| ASND | ASCENDIS PHARMA A/S - ADR | 10,108,400 | $1.528B | 19.4% | $79.32 | — | — | 04351P101 |
| PCVX | VAXCYTE INC | 8,203,754 | $560M | 7.1% | $36.65 | +89.0% | — | 92243G108 |
| LEGN | LEGEND BIOTECH CORP-ADR | 6,861,097 | $385M | 4.9% | $58.01 | — | — | 52490G102 |
| JANX | JANUX THERAPEUTICS INC | 9,165,652 | $345M | 4.4% | $21.69 | +0.4% | — | 47103J105 |
| — | AEROVATE THERAPEUTICS INC | 8,263,982 | $244M | 3.1% | $22.83 | — | — | 008064107 |
| RYTM | RHYTHM PHARMACEUTICALS INC | 5,330,412 | $231M | 2.9% | $23.94 | +82.8% | — | 76243J105 |
| EVH | EVOLENT HEALTH INC - A | 5,736,132 | $188M | 2.4% | $30.08 | +6.1% | — | 30050B101 |
| NAMS | NEWAMSTERDAM PHARMA CO NV | 7,864,000 | $186M | 2.4% | $11.79 | +72.1% | — | N62509109 |
| RXST | RXSIGHT INC | 3,442,825 | $178M | 2.3% | $15.75 | +211.7% | — | 78349D107 |
| TYRA | TYRA BIOSCIENCES INC | 10,416,609 | $171M | 2.2% | $18.29 | -10.3% | — | 90240B106 |
| EWTX | EDGEWISE THERAPEUTICS INC | 8,909,091 | $163M | 2.1% | $15.89 | 0.0% | — | 28036F105 |
| FDMT | 4D MOLECULAR THERAPEUTICS IN | 5,051,511 | $161M | 2.0% | $19.29 | +32.2% | — | 35104E100 |
| BIIB | BIOGEN INC | 740,727 | $160M | 2.0% | $221.34 | +5.8% | — | 09062X103 |
| PEPG | PEPGEN INC | 10,689,545 | $157M | 2.0% | $11.31 | +4.4% | — | 713317105 |
| GERN | GERON CORP | 46,202,425 | $152M | 1.9% | $2.42 | -7.9% | — | 374163103 |
| — | 89BIO INC | 12,766,948 | $149M | 1.9% | $16.06 | — | — | 282559103 |
| DYN | DYNE THERAPEUTICS INC | 4,954,779 | $141M | 1.8% | $22.62 | 0.0% | — | 26818M108 |
| APGE | APOGEE THERAPEUTICS INC | 1,977,901 | $131M | 1.7% | $22.03 | +98.2% | — | 03770N101 |
| DAWN | DAY ONE BIOPHARMACEUTICALS I | 7,809,852 | $129M | 1.6% | $17.63 | -15.1% | — | 23954D109 |
| NKTX | NKARTA INC | 10,805,129 | $117M | 1.5% | $20.85 | -50.1% | — | 65487U108 |
| WVE | WAVE LIFE SCIENCES LTD | 18,202,009 | $112M | 1.4% | $8.66 | -42.2% | — | Y95308105 |
| SPRY | ARS PHARMACEUTICALS INC | 10,860,977 | $111M | 1.4% | $6.66 | +12.0% | — | 82835W108 |
| FULC | FULCRUM THERAPEUTICS INC | 11,609,704 | $110M | 1.4% | $7.35 | +21.5% | — | 359616109 |
| — | VERONA PHARMA PLC - ADR | 6,317,990 | $102M | 1.3% | $7.68 | — | — | 925050106 |
| LENZ | LENZ THERAPEUTICS INC | 4,178,823 | $93.31M | 1.2% | $20.79 | 0.0% | — | 52635N103 |
| — | INHIBRX INC | 2,629,837 | $91.94M | 1.2% | $23.48 | — | — | 45720L107 |
| RNAM | AVIDITY BIOSCIENCES INC | 3,282,180 | $83.76M | 1.1% | $16.66 | -5.9% | — | 05370A108 |
| AXSM | AXSOME THERAPEUTICS INC | 1,000,000 | $79.8M | 1.0% | $73.77 | +13.8% | — | 05464T104 |
| — | LONGBOARD PHARMACEUTICALS IN | 3,289,119 | $71.04M | 0.9% | $21.60 | — | — | 54300N103 |
| DNTH | DIANTHUS THERAPEUTICS INC | 2,333,000 | $69.99M | 0.9% | $21.73 | 0.0% | — | 252828108 |
| GHRS | GH RESEARCH PLC | 6,251,714 | $66.64M | 0.8% | $16.91 | -53.0% | — | G3855L106 |
| GPCR | STRUCTURE THERAPEUTICS INC | 1,510,362 | $64.73M | 0.8% | $42.18 | — | — | 86366E106 |
| MLYS | MINERALYS THERAPEUTICS INC | 4,850,984 | $62.63M | 0.8% | $15.29 | -19.2% | — | 603170101 |
| — | ASTRIA THERAPEUTICS INC | 4,413,150 | $62.12M | 0.8% | $14.07 | — | — | 04635X102 |
| CGON | CG ONCOLOGY INC | 1,397,433 | $61.35M | 0.8% | $40.84 | 0.0% | — | 156944100 |
| ABOS | ACUMEN PHARMACEUTICALS INC | 14,932,063 | $60.47M | 0.8% | $13.02 | -71.1% | — | 00509G209 |
| — | ITEOS THERAPEUTICS INC | 4,417,259 | $60.25M | 0.8% | $24.67 | — | — | 46565G104 |
| SLDB | SOLID BIOSCIENCES INC | 4,330,446 | $57.68M | 0.7% | $7.14 | +31.1% | — | 83422E204 |
| MDGL | MADRIGAL PHARMACEUTICALS INC | 204,500 | $54.61M | 0.7% | $188.22 | +25.2% | — | 558868105 |
| — | VOR BIOPHARMA INC | 22,748,880 | $53.91M | 0.7% | $24.47 | — | — | 929033108 |
| PRAX | PRAXIS PRECISION MEDICINES I | 828,380 | $50.55M | 0.6% | $44.86 | 0.0% | — | 74006W207 |
| URGN | UROGEN PHARMA LTD | 3,083,430 | $46.25M | 0.6% | $14.46 | +13.0% | — | M96088105 |
| LRMR | LARIMAR THERAPEUTICS INC | 6,045,351 | $45.88M | 0.6% | $7.79 | 0.0% | — | 517125100 |
| CTKB | CYTEK BIOSCIENCES INC | 6,809,404 | $45.69M | 0.6% | $20.70 | -61.8% | — | 23285D109 |
| CCCC | C4 THERAPEUTICS INC | 4,878,000 | $39.85M | 0.5% | $2.28 | +239.9% | — | 12529R107 |
| HOWL | WEREWOLF THERAPEUTICS INC | 6,144,881 | $39.82M | 0.5% | $10.47 | -44.3% | — | 95075A107 |
| ELVN | ENLIVEN THERAPEUTICS INC | 2,122,465 | $37.33M | 0.5% | $20.34 | -24.6% | — | 29337E102 |
| CLYM | ELIEM THERAPEUTICS INC | 13,150,849 | $36.03M | 0.5% | $20.66 | -86.7% | — | 28658R106 |
| ACRV | ACRIVON THERAPEUTICS INC | 4,810,508 | $34.4M | 0.4% | $12.69 | -63.4% | — | 004890109 |
| TSHA | TAYSHA GENE THERAPIES INC | 10,872,503 | $31.2M | 0.4% | $1.87 | +11.6% | — | 877619106 |
| BOLD | BOUNDLESS BIO INC | 2,180,631 | $31.07M | 0.4% | $14.25 | 0.0% | — | 10170A100 |
| MGNX | MACROGENICS INC | 2,082,021 | $30.65M | 0.4% | $6.75 | +123.9% | — | 556099109 |
| TNYA | TENAYA THERAPEUTICS INC | 5,755,050 | $30.1M | 0.4% | $7.05 | -32.1% | — | 87990A106 |
| — | CYBIN INC | 58,139,535 | $24.04M | 0.3% | $0.41 | — | — | 23256X100 |
| ANRO | ALTO NEUROSCIENCE INC | 1,385,491 | $21.27M | 0.3% | $15.65 | 0.0% | — | 02157Q109 |
| CRVO | CERVOMED INC | 861,573 | $20.07M | 0.3% | $13.35 | 0.0% | — | 15713L109 |
| VXRT | VAXART INC | 15,384,615 | $20M | 0.3% | $1.05 | 0.0% | — | 92243A200 |
| BCYC | BICYCLE THERAPEUTICS PLC-ADR | 800,000 | $19.92M | 0.3% | $20.09 | — | — | 088786108 |
| EYPT | EYEPOINT PHARMACEUTICALS INC | 938,591 | $19.4M | 0.2% | $24.76 | 0.0% | — | 30233G209 |
| — | THIRD HARMONIC BIO INC | 2,033,056 | $19.19M | 0.2% | $8.80 | — | — | 88427A107 |
| PLRX | PLIANT THERAPEUTICS INC | 1,281,000 | $19.09M | 0.2% | $28.47 | -42.1% | — | 729139105 |
| SERA | SERA PROGNOSTICS INC-A | 2,024,221 | $18.42M | 0.2% | $7.92 | 0.0% | — | 81749D107 |
| MGX | METAGENOMI INC | 1,744,415 | $18.4M | 0.2% | $11.50 | 0.0% | — | 59102M104 |
| IMTX | IMMATICS NV | 1,750,000 | $18.39M | 0.2% | $11.66 | 0.0% | — | N44445109 |
| ANTX | AN2 THERAPEUTICS INC | 5,551,295 | $18.04M | 0.2% | $13.91 | -21.8% | — | 037326105 |
| — | REGULUS THERAPEUTICS INC | 6,250,000 | $18M | 0.2% | $2.88 | — | — | 75915K309 |
| BDTX | BLACK DIAMOND THERAPEUTICS I | 3,525,754 | $17.88M | 0.2% | $22.74 | -82.3% | — | 09203E105 |
| — | ADICET BIO INC | 7,541,000 | $17.72M | 0.2% | $2.35 | — | — | 007002108 |
| ARVN | ARVINAS INC | 421,348 | $17.39M | 0.2% | $23.38 | +86.9% | — | 04335A105 |
| LXEO | LEXEO THERAPEUTICS INC | 660,938 | $10.36M | 0.1% | $15.64 | 0.0% | — | 52886X107 |
| — | CHIMERIX INC | 8,800,000 | $9.328M | 0.1% | $0.96 | — | — | 16934W106 |
| — | IGM BIOSCIENCES INC | 937,500 | $9.047M | 0.1% | $9.23 | — | — | 449585108 |
| CMPS | COMPASS PATHWAYS PLC | 791,359 | $6.584M | 0.1% | $7.40 | — | — | 20451W101 |
| — | CUREVAC NV | 1,965,707 | $5.956M | 0.1% | $6.97 | — | — | N2451R105 |
| — | UNICYCIVE THERAPEUTICS INC | 3,470,688 | $4.79M | 0.1% | $0.86 | — | — | 90466Y103 |
| NAMSW | NEWAMSTERDAM PHARMA CO NV-27 | 333,333 | $3.68M | 0.0% | $0.87 | — | — | N62509117 |