Location: Boston, MA
CIK: 0001346824 · Show all filings
Period: Q2 2021 (← Previous) (Next →)
Filing Date: Aug 16, 2021
Total Value: $6.23B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| ASND | ASCENDIS PHARMA A/S | 6,806,341 | $895M | 14.4% | $64.24 | — | SPONSORED ADR | 04351P101 |
| NVAX | NOVAVAX INC | 2,559,918 | $543M | 8.7% | $84.76 | +116.2% | COM NEW | 670002401 |
| — | FORMA THERAPEUTICS HLDGS INC | 9,011,651 | $224M | 3.6% | $46.49 | — | SHS | 34633R104 |
| JANX | JANUX THERAPEUTICS INC | 8,670,644 | $216M | 3.5% | $22.27 | 0.0% | COM | 47103J105 |
| — | VOR BIOPHARMA INC | 11,120,973 | $207M | 3.3% | $43.10 | — | COM | 929033108 |
| — | AEROVATE THERAPEUTICS INC | 8,263,982 | $189M | 3.0% | $22.83 | — | COM | 008064107 |
| NKTX | NKARTA INC | 5,605,129 | $178M | 2.9% | $29.47 | -2.2% | COM | 65487U108 |
| MGNX | MACROGENICS INC | 5,943,594 | $160M | 2.6% | $20.04 | +46.1% | COM | 556099109 |
| — | CONNECT BIOPHARMA HLDGS LTD | 6,991,003 | $137M | 2.2% | $19.09 | — | ADS | 207523101 |
| TGTX | TG THERAPEUTICS INC | 3,342,743 | $130M | 2.1% | $11.95 | +228.6% | COM | 88322Q108 |
| — | IMMUNOGEN INC | 18,417,458 | $121M | 1.9% | $5.36 | — | COM | 45253H101 |
| AVIR | ATEA PHARMACEUTICALS INC | 5,368,451 | $115M | 1.9% | $32.23 | -6.8% | COM | 04683R106 |
| — | ITEOS THERAPEUTICS INC | 4,417,259 | $113M | 1.8% | $24.67 | — | COM | 46565G104 |
| DAWN | DAY ONE BIOPHARMACEUTICALS I | 4,965,588 | $113M | 1.8% | $20.76 | 0.0% | COM | 23954D109 |
| AXSM | AXSOME THERAPEUTICS INC | 1,655,447 | $112M | 1.8% | $68.14 | -11.9% | COM | 05464T104 |
| PHAT | PHATHOM PHARMACEUTICALS INC | 3,115,008 | $105M | 1.7% | $25.67 | +39.5% | COM | 71722W107 |
| — | INSTIL BIO INC | 4,870,793 | $94.1M | 1.5% | $25.08 | — | COM | 45783C101 |
| RCKT | ROCKET PHARMACEUTICALS INC COM | 2,107,149 | $93.33M | 1.5% | $36.45 | +19.1% | COM | 77313F106 |
| — | 89BIO INC | 4,965,769 | $92.86M | 1.5% | $25.74 | — | COM | 282559103 |
| — | ZOGENIX INC | 5,283,976 | $91.31M | 1.5% | $26.04 | — | COM NEW | 98978L204 |
| PCVX | VAXCYTE INC | 3,865,808 | $87.02M | 1.4% | $31.88 | -35.8% | COM | 92243G108 |
| — | KINNATE BIOPHARMA INC | 3,593,052 | $83.65M | 1.3% | $39.78 | — | COM | 49705R105 |
| — | GRAPHITE BIO INC | 2,698,369 | $82.92M | 1.3% | $30.73 | — | COM | 38870X104 |
| TVTX | TRAVERE THERAPEUTICS INC | 5,614,428 | $81.92M | 1.3% | $24.15 | -18.3% | COM | 89422G107 |
| HOWL | WEREWOLF THERAPEUTICS INC | 4,291,881 | $74.85M | 1.2% | $13.70 | 0.0% | COM | 95075A107 |
| RYTM | RHYTHM PHARMACEUTICALS INC | 4,871,067 | $71.08M | 1.1% | $24.79 | -16.2% | COM | 76243J105 |
| — | CYTEIR THERAPEUTICS INC | 3,247,117 | $69.49M | 1.1% | $21.40 | — | COM | 23284P103 |
| GHRS | GH RESEARCH PLC | 2,978,955 | $64.73M | 1.0% | $20.43 | 0.0% | ORDINARY SHARES | G3855L106 |
| OLMA | OLEMA PHARMACEUTICALS INC | 2,150,404 | $60.17M | 1.0% | $46.89 | -39.3% | COM | 68062P106 |
| DYN | DYNE THERAPEUTICS INC | 2,805,045 | $59.02M | 0.9% | $21.96 | -14.4% | COM | 26818M108 |
| PMVP | PMV PHARMACEUTICALS INC | 1,710,265 | $58.42M | 0.9% | $36.80 | -9.2% | COM | 69353Y103 |
| — | KALA PHARMACEUTICALS INC | 10,874,613 | $57.63M | 0.9% | $10.65 | — | COM | 483119103 |
| — | CURIS INC | 7,140,091 | $57.62M | 0.9% | $8.19 | — | COM NEW | 231269200 |
| — | CEREVEL THERAPEUTICS HLDNG INC | 2,200,000 | $56.36M | 0.9% | $16.58 | — | COM | 15678U128 |
| EWTX | EDGEWISE THERAPEUTICS INC | 2,613,623 | $55.75M | 0.9% | $32.43 | -15.7% | COM | 28036F105 |
| — | ORCHARD THERAPEUTICS PLC | 12,315,213 | $54.06M | 0.9% | $10.43 | — | ADS | 68570P101 |
| SPRY | SILVERBACK THERAPEUTICS INC | 1,742,186 | $53.82M | 0.9% | $33.40 | -4.0% | COM | 82835W108 |
| — | VERVE THERAPEUTICS INC | 880,284 | $53.04M | 0.9% | $60.25 | — | COM | 92539P101 |
| CCCC | C4 THERAPEUTICS INC | 1,377,569 | $52.13M | 0.8% | $29.00 | +23.5% | COM STK | 12529R107 |
| WVE | WAVE LIFE SCIENCES LTD | 7,775,207 | $51.78M | 0.8% | $17.26 | -62.1% | SHS | Y95308105 |
| — | TRILLIUM THERAPEUTICS INC | 5,290,481 | $51.32M | 0.8% | $4.04 | — | COM NEW | 89620X506 |
| — | ACHILLES THERAPEUTICS PLC | 5,014,687 | $49.09M | 0.8% | $11.66 | — | SPONSORED ADS | 00449L102 |
| — | CHEMOCENTRYX INC | 3,496,639 | $46.82M | 0.8% | $42.10 | — | COM | 16383L106 |
| KALV | KALVISTA PHARMACEUTICALS INC | 1,930,322 | $46.25M | 0.7% | $26.18 | -0.1% | COM | 483497103 |
| ARDX | ARDELYX INC | 6,077,294 | $46.07M | 0.7% | $6.19 | +19.4% | COM | 039697107 |
| — | SOLID BIOSCIENCES INC | 12,367,873 | $45.27M | 0.7% | $7.59 | — | COM | 83422E105 |
| DSGN | DESIGN THERAPEUTICS INC | 2,186,636 | $43.49M | 0.7% | $31.14 | -19.0% | COM | 25056L103 |
| GERN | GERON CORP | 30,126,299 | $42.48M | 0.7% | $1.49 | -2.7% | COM | 374163103 |
| — | SATSUMA PHARMACEUTICALS INC | 5,914,252 | $41.7M | 0.7% | $13.11 | — | COM | 80405P107 |
| LEGN | LEGEND BIOTECH CORP | 977,503 | $40.13M | 0.6% | $41.05 | — | SPONSORED ADS | 52490G102 |
| — | BOLT BIOTHERAPEUTICS INC | 2,378,325 | $36.77M | 0.6% | $32.91 | — | COM | 097702104 |
| — | INOZYME PHARMA INC | 2,003,653 | $34.14M | 0.5% | $26.29 | — | COM | 45790W108 |
| — | VERONA PHARMA PLC | 5,100,000 | $33.35M | 0.5% | $6.24 | — | SPONSORED ADS | 925050106 |
| BDTX | BLACK DIAMOND THERAPEUTICS INC | 2,589,904 | $31.57M | 0.5% | $30.22 | -34.6% | COM | 09203E105 |
| — | AKOUOS INC | 2,281,249 | $28.63M | 0.5% | $22.50 | — | COM | 00973J101 |
| CNTA | CENTESSA PHARMACEUTICALS PLC | 1,280,300 | $28.43M | 0.5% | $22.21 | — | SPONSORED ADS | 152309100 |
| IPSC | CENTURY THERAPEUTICS INC | 914,094 | $26.82M | 0.4% | $25.37 | 0.0% | COM | 15673T100 |
| NAUT | NAUTILUS BIOTECHNOLOGY INC | 2,471,430 | $24.96M | 0.4% | $10.83 | 0.0% | COM | 63909J108 |
| CTMX | CYTOMX THERAPEUTICS INC | 3,500,000 | $22.16M | 0.4% | $7.92 | -1.6% | COM | 23284F105 |
| — | SCPHARMACEUTICALS INC | 2,731,170 | $16.69M | 0.3% | $10.74 | — | COM | 810648105 |
| LRMR | LARIMAR THERAPEUTICS INC | 1,515,151 | $14.88M | 0.2% | $11.65 | -3.0% | COM | 517125100 |
| — | BCTG ACQUISITION CORP | 1,250,000 | $14.22M | 0.2% | $10.36 | — | COM | 05492W103 |
| ENTX | ENTERA BIO LTD | 2,353,000 | $14.07M | 0.2% | $3.70 | 0.0% | SHS | M40527109 |
| — | BCLS ACQUISITION CORP | 1,250,000 | $13.16M | 0.2% | $11.14 | — | COM CL A | G0904B105 |
| — | CONCERT PHARMACEUTICALS INC | 3,033,603 | $12.8M | 0.2% | $7.30 | — | COM | 206022105 |
| — | CATABASIS PHARMACEUTICALS IN | 5,947,861 | $12.55M | 0.2% | $2.11 | — | COM NEW | 14875P206 |
| MIST | MILESTONE PHARMACEUTICALS INC | 2,246,503 | $12.36M | 0.2% | $7.17 | -20.9% | COM | 59935V107 |
| — | THERAPEUTICS ACQUISITION COR | 1,098,318 | $11.28M | 0.2% | $10.27 | — | COM CL A | 88339T103 |
| EYPT | EYEPOINT PHARMACEUTICALS INC | 1,250,000 | $11.24M | 0.2% | $11.25 | -14.7% | COM NEW | 30233G209 |
| — | ARYA SCIENCES ACQU CORP IV | 1,000,000 | $10.72M | 0.2% | $10.47 | — | CL A | G31659108 |
| OCUL | OCULAR THERAPEUTIX INC | 750,000 | $10.63M | 0.2% | $6.63 | +129.4% | COM | 67576A100 |
| — | PHASEBIO PHARMACEUTICALS INC | 2,850,000 | $10.6M | 0.2% | $3.46 | — | COM | 717224109 |
| — | IKENA ONCOLOGY INC | 750,000 | $10.53M | 0.2% | $28.25 | — | COM | 45175G108 |
| ORIC | ORIC PHARMACEUTICALS INC | 584,000 | $10.33M | 0.2% | $28.69 | -23.6% | COM | 68622P109 |
| — | FRAZIER LIFESCIENCES ACQUISITION CO | 1,000,000 | $10.05M | 0.2% | $10.38 | — | UNIT 12/09/2025 | G3710A121 |
| — | FS DEVELOPMENT CORP II | 1,000,000 | $9.98M | 0.2% | $9.96 | — | COM CL A | 30318F100 |
| — | THERAPEUTICSMD INC | 7,812,500 | $9.297M | 0.1% | $1.21 | — | COM | 88338N107 |
| CGEM | CULLINAN ONCOLOGY INC | 350,000 | $9.013M | 0.1% | $40.60 | -24.2% | COM | 230031106 |
| COGT | COGENT BIOSCIENCES INC | 1,025,641 | $8.318M | 0.1% | $10.99 | -23.1% | COM | 19240Q201 |
| BMEA | BIOMEA FUSION INC | 500,000 | $7.805M | 0.1% | $17.65 | 0.0% | COM | 09077A106 |
| CVRX | CVRX INC | 275,000 | $7.7M | 0.1% | $28.00 | 0.0% | COM | 126638105 |
| — | 5 01 ACQUISITION CORP | 750,000 | $7.478M | 0.1% | $10.17 | — | COM CL A | 33836P105 |
| MLTX | HELIX ACQUISITION CORP | 700,000 | $7.245M | 0.1% | $11.37 | — | COM CL A | G4444C102 |
| — | HEALTH SCIENCES ACQ CORP 2 | 625,000 | $6.375M | 0.1% | $11.00 | — | ORD SHS | G4411D109 |
| VRDN | VIRIDIAN THERAPEUTICS INC | 312,328 | $5.712M | 0.1% | $18.72 | -8.6% | COM | 92790C104 |
| — | SYROS PHARMACEUTICALS INC | 900,000 | $4.905M | 0.1% | $7.48 | — | COM | 87184Q107 |
| — | AERPIO PHARMACEUTICALS INC | 2,693,309 | $4.552M | 0.1% | $1.69 | — | COM | 00810B105 |
| — | CEREVEL THERAPEUTICS HLDNG INC | 233,333 | $3.358M | 0.1% | $5.65 | — | *W EXP 06/09/2027 | 15678U102 |
| NTLA | INTELLIA THERAPEUTICS INC | 15,000 | $2.429M | 0.0% | $77.87 | 0.0% | COM | 45826J105 |
| — | IMARA INC | 248,804 | $1.966M | 0.0% | $16.03 | — | COM | 45249V107 |
| — | SERES THERAPEUTICS INC | 5,105,547 | $1.9M | 0.0% | $15.00 | — | COM | 81750R102 |
| — | RENEO PHARMACEUTICALS INC | 62,217 | $580K | 0.0% | $9.32 | — | COM | 75974E103 |