Integral Health Asset Management, LLC Quant / Systematic

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
DXCM	DEXCOM INC	500,000	$33,185	1.6%	$64.65	0.0%	COM	252131107
TEVA	TEVA PHARMACEUTICAL INDS LTD	1,000,000	$31,210	1.5%	$31.21	—	SPONSORED ADS	881624209
TFX	TELEFLEX INCORPORATED	250,000	$30,510	1.5%	$121.00	0.0%	COM	879369106
MRK	MERCK & CO INC	250,000	$26,315	1.3%	$93.24	0.0%	COM	58933Y105
BIIB	BIOGEN INC	100,000	$17,599	0.9%	$163.37	0.0%	COM	09062X103
UNH	UNITEDHEALTH GROUP INC	50,000	$16,506	0.8%	$337.21	0.0%	COM	91324P102
SLNO	SOLENO THERAPEUTICS INC	325,000	$15,048	0.7%	$54.83	0.0%	COM	834203309
PRAX	PRAXIS PRECISION MEDICINES I	40,000	$11,790	0.6%	$186.22	0.0%	COM NEW	74006W207
MLYS	MINERALYS THERAPEUTICS INC	250,000	$9,073	0.5%	$12.33	+225.3%	CALL	603170101
CELC	CELCUITY INC	80,000	$7,979	0.4%	$82.21	0.0%	COM	15102K100
LNTH	LANTHEUS HLDGS INC	100,000	$6,655	0.3%	$58.19	0.0%	COM	516544103
BRKR	BRUKER CORP	125,000	$5,889	0.3%	$42.23	0.0%	COM	116794108
—	MIND MEDICINE MINDMED INC	350,000	$4,687	0.2%	$13.39	—	COM NEW	60255C885
SNDX	SYNDAX PHARMACEUTICALS INC	200,000	$4,202	0.2%	$17.45	0.0%	COM	87164F105
MAZE	MAZE THERAPEUTICS INC	100,000	$4,143	0.2%	$34.37	0.0%	COM	578784100
EYPT	EYEPOINT INC	200,000	$3,654	0.2%	$14.17	0.0%	COM NEW	30233G209
IKT	INHIBIKASE THERAPEUTICS INC	1,750,000	$3,588	0.2%	$1.59	0.0%	COM NEW	45719W205
VKTX	VIKING THERAPEUTICS INC	100,000	$3,518	0.2%	$35.43	0.0%	COM	92686J106
GPCR	STRUCTURE THERAPEUTICS INC	50,000	$3,478	0.2%	$69.55	—	SPONSORED ADS	86366E106
SGHT	SIGHT SCIENCES INC	425,000	$3,370	0.2%	$6.39	0.0%	COM	82657M105
GOSS	GOSSAMER BIO INC	1,000,000	$3,100	0.2%	$2.85	0.0%	COM	38341P102
EVMN	EVOMMUNE INC	125,000	$2,140	0.1%	$18.78	0.0%	COM SHS	30054Y107
TNGX	TANGO THERAPEUTICS INC	200,000	$1,772	0.1%	$8.62	0.0%	COM	87583X109
BCRX	BIOCRYST PHARMACEUTICALS INC	200,000	$1,560	0.1%	$7.23	0.0%	COM	09058V103

Increased Positions (34)

RVMD REVOLUTION MEDICINES INC 4.7%

Value ($000) $95,580 (+411.7%) Shares 1,200,000 (+200.0%) Est. Cost $56.25 Unrealized +16.6%

REGN REGENERON PHARMACEUTICALS 4.0%

Value ($000) $81,046 (+188.3%) Shares 105,000 (+110.0%) Est. Cost $620.32 Unrealized +9.4%

ISRG INTUITIVE SURGICAL INC 3.1%

Value ($000) $62,300 (+457.2%) Shares 110,000 (+340.0%) Est. Cost $520.44 Unrealized +2.3%

MDT MEDTRONIC PLC 3.2%

Value ($000) $64,841 (+353.9%) Shares 675,000 (+350.0%) Est. Cost $94.24 Unrealized +3.1%

VERA VERA THERAPEUTICS INC 4.5%

Value ($000) $91,152 (+84.5%) Shares 1,800,000 (+5.9%) Est. Cost $35.24 Unrealized +0.8%

RYTM RHYTHM PHARMACEUTICALS INC 2.5%

Value ($000) $50,844 (+128.8%) Shares 475,000 (+115.9%) Est. Cost $91.96 Unrealized +15.3%

GKOS GLAUKOS CORP 1.8%

Value ($000) $36,696 (+350.0%) Shares 325,000 (+225.0%) Est. Cost $94.71 Unrealized +0.9%

CVS CVS HEALTH CORP 2.0%

Value ($000) $39,680 (+163.2%) Shares 500,000 (+150.0%) Est. Cost $69.51 Unrealized +13.2%

CAH CARDINAL HEALTH INC 2.0%

Value ($000) $41,100 (+101.4%) Shares 200,000 (+53.8%) Est. Cost $161.33 Unrealized +16.4%

COO COOPER COS INC 1.3%

Value ($000) $26,637 (+309.0%) Shares 325,000 (+242.1%) Est. Cost $74.91 Unrealized -0.1%

PEN PENUMBRA INC 1.5%

Value ($000) $31,091 (+145.5%) Shares 100,000 (+100.0%) Est. Cost $271.60 Unrealized +1.7%

ALHC ALIGNMENT HEALTHCARE INC 2.2%

Value ($000) $43,450 (+55.6%) Shares 2,200,000 (+37.5%) Est. Cost $15.51 Unrealized +15.8%

QURE UNIQURE NV 1.1%

Value ($000) $21,537 (-38.5%) Shares 900,000 (+50.0%) Est. Cost $18.84 Unrealized +104.9%

LFST LIFESTANCE HEALTH GROUP INC 1.0%

Value ($000) $21,120 (+156.0%) Shares 3,000,000 (+100.0%) Est. Cost $5.47 Unrealized +10.4%

CNC CENTENE CORP DEL 1.3%

Value ($000) $26,748 (+87.4%) Shares 650,000 (+62.5%) Est. Cost $32.98 Unrealized +13.5%

EW EDWARDS LIFESCIENCES CORP 1.4%

Value ($000) $27,706 (+78.1%) Shares 325,000 (+62.5%) Est. Cost $76.30 Unrealized +7.6%

IRTC IRHYTHM TECHNOLOGIES INC 1.1%

Value ($000) $23,067 (+106.3%) Shares 130,000 (+100.0%) Est. Cost $158.93 Unrealized +11.5%

UPB UPSTREAM BIO INC 1.0%

Value ($000) $20,363 (+88.3%) Shares 750,000 (+30.4%) Est. Cost $17.72 Unrealized +40.5%

SRRK SCHOLAR ROCK HLDG CORP 0.7%

Value ($000) $13,215 (+254.9%) Shares 300,000 (+200.0%) Est. Cost $31.38 Unrealized +19.5%

AZN ASTRAZENECA PLC 1.6%

Value ($000) $32,176 (+39.8%) Shares 350,000 (+16.7%) Est. Cost $74.98 Unrealized —

NVS NOVARTIS AG 1.7%

Value ($000) $34,468 (+34.4%) Shares 250,000 (+25.0%) Est. Cost $116.76 Unrealized —

ASND ASCENDIS PHARMA A/S 1.0%

Value ($000) $19,192 (+60.9%) Shares 90,000 (+50.0%) Est. Cost $203.62 Unrealized —

BHVN BIOHAVEN LTD 0.8%

Value ($000) $16,935 (+73.6%) Shares 1,500,000 (+130.8%) Est. Cost $16.02 Unrealized -22.6%

ROIV ROIVANT SCIENCES LTD 0.9%

Value ($000) $18,445 (+62.5%) Shares 850,000 (+13.3%) Est. Cost $12.14 Unrealized +62.5%

RGNX REGENXBIO INC 0.9%

Value ($000) $17,280 (+62.8%) Shares 1,200,000 (+9.1%) Est. Cost $13.18 Unrealized -5.4%

TARA PROTARA THERAPEUTICS INC 0.6%

Value ($000) $11,993 (+96.9%) Shares 2,250,000 (+60.7%) Est. Cost $4.11 Unrealized +35.3%

BEAM BEAM THERAPEUTICS INC 0.8%

Value ($000) $15,246 (+57.0%) Shares 550,000 (+37.5%) Est. Cost $19.62 Unrealized +30.0%

DNTH DIANTHUS THERAPEUTICS INC 0.6%

Value ($000) $11,333 (+92.0%) Shares 275,000 (+83.3%) Est. Cost $31.56 Unrealized +22.8%

SANA SANA BIOTECHNOLOGY INC 0.6%

Value ($000) $12,210 (+72.0%) Shares 3,000,000 (+50.0%) Est. Cost $5.31 Unrealized -15.6%

ELV ELEVANCE HEALTH INC FORMERLY 1.0%

Value ($000) $21,033 (+30.2%) Shares 60,000 (+20.0%) Est. Cost $384.68 Unrealized -12.5%

DOCS DOXIMITY INC 0.9%

Value ($000) $17,712 (+34.5%) Shares 400,000 (+122.2%) Est. Cost $60.22 Unrealized -6.8%

FMS FRESENIUS MEDICAL CARE AG 0.8%

Value ($000) $15,483 (+30.7%) Shares 650,000 (+44.4%) Est. Cost $23.00 Unrealized —

ORIC ORIC PHARMACEUTICALS INC 0.5%

Value ($000) $9,816 (-9.1%) Shares 1,200,000 (+33.3%) Est. Cost $7.91 Unrealized +45.5%

ACLX ARCELLX INC 0.6%

Value ($000) $13,040 (+5.9%) Shares 200,000 (+33.3%) Est. Cost $73.94 Unrealized +7.9%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
RVMD	REVOLUTION MEDICINES INC	1,200,000 (+200.0%)	$95,580 (+411.7%)	4.7%	$56.25	+16.6%	COM	76155X100
REGN	REGENERON PHARMACEUTICALS	105,000 (+110.0%)	$81,046 (+188.3%)	4.0%	$620.32	+9.4%	COM	75886F107
ISRG	INTUITIVE SURGICAL INC	110,000 (+340.0%)	$62,300 (+457.2%)	3.1%	$520.44	+2.3%	COM NEW	46120E602
MDT	MEDTRONIC PLC	675,000 (+350.0%)	$64,841 (+353.9%)	3.2%	$94.24	+3.1%	SHS	G5960L103
VERA	VERA THERAPEUTICS INC	1,800,000 (+5.9%)	$91,152 (+84.5%)	4.5%	$35.24	+0.8%	CL A	92337R101
RYTM	RHYTHM PHARMACEUTICALS INC	475,000 (+115.9%)	$50,844 (+128.8%)	2.5%	$91.96	+15.3%	COM	76243J105
GKOS	GLAUKOS CORP	325,000 (+225.0%)	$36,696 (+350.0%)	1.8%	$94.71	+0.9%	COM	377322102
CVS	CVS HEALTH CORP	500,000 (+150.0%)	$39,680 (+163.2%)	2.0%	$69.51	+13.2%	COM	126650100
CAH	CARDINAL HEALTH INC	200,000 (+53.8%)	$41,100 (+101.4%)	2.0%	$161.33	+16.4%	COM	14149Y108
COO	COOPER COS INC	325,000 (+242.1%)	$26,637 (+309.0%)	1.3%	$74.91	-0.1%	COM	216648501
PEN	PENUMBRA INC	100,000 (+100.0%)	$31,091 (+145.5%)	1.5%	$271.60	+1.7%	COM	70975L107
ALHC	ALIGNMENT HEALTHCARE INC	2,200,000 (+37.5%)	$43,450 (+55.6%)	2.2%	$15.51	+15.8%	COM	01625V104
QURE	UNIQURE NV	900,000 (+50.0%)	$21,537 (-38.5%)	1.1%	$18.84	+104.9%	SHS	N90064101
LFST	LIFESTANCE HEALTH GROUP INC	3,000,000 (+100.0%)	$21,120 (+156.0%)	1.0%	$5.47	+10.4%	COM	53228F101
CNC	CENTENE CORP DEL	650,000 (+62.5%)	$26,748 (+87.4%)	1.3%	$32.98	+13.5%	COM	15135B101
EW	EDWARDS LIFESCIENCES CORP	325,000 (+62.5%)	$27,706 (+78.1%)	1.4%	$76.30	+7.6%	COM	28176E108
IRTC	IRHYTHM TECHNOLOGIES INC	130,000 (+100.0%)	$23,067 (+106.3%)	1.1%	$158.93	+11.5%	COM	450056106
UPB	UPSTREAM BIO INC	750,000 (+30.4%)	$20,363 (+88.3%)	1.0%	$17.72	+40.5%	COM	91678A107
SRRK	SCHOLAR ROCK HLDG CORP	300,000 (+200.0%)	$13,215 (+254.9%)	0.7%	$31.38	+19.5%	COM	80706P103
AZN	ASTRAZENECA PLC	350,000 (+16.7%)	$32,176 (+39.8%)	1.6%	$74.98	—	SPONSORED ADR	046353108
NVS	NOVARTIS AG	250,000 (+25.0%)	$34,468 (+34.4%)	1.7%	$116.76	—	SPONSORED ADR	66987V109
ASND	ASCENDIS PHARMA A/S	90,000 (+50.0%)	$19,192 (+60.9%)	1.0%	$203.62	—	SPONSORED ADR	04351P101
BHVN	BIOHAVEN LTD	1,500,000 (+130.8%)	$16,935 (+73.6%)	0.8%	$16.02	-22.6%	COM	G1110E107
ROIV	ROIVANT SCIENCES LTD	850,000 (+13.3%)	$18,445 (+62.5%)	0.9%	$12.14	+62.5%	SHS	G76279101
RGNX	REGENXBIO INC	1,200,000 (+9.1%)	$17,280 (+62.8%)	0.9%	$13.18	-5.4%	COM	75901B107
TARA	PROTARA THERAPEUTICS INC	2,250,000 (+60.7%)	$11,993 (+96.9%)	0.6%	$4.11	+35.3%	COM STK	74365U107
BEAM	BEAM THERAPEUTICS INC	550,000 (+37.5%)	$15,246 (+57.0%)	0.8%	$19.62	+30.0%	COM	07373V105
DNTH	DIANTHUS THERAPEUTICS INC	275,000 (+83.3%)	$11,333 (+92.0%)	0.6%	$31.56	+22.8%	COM	252828108
SANA	SANA BIOTECHNOLOGY INC	3,000,000 (+50.0%)	$12,210 (+72.0%)	0.6%	$5.31	-15.6%	COM	799566104
ELV	ELEVANCE HEALTH INC FORMERLY	60,000 (+20.0%)	$21,033 (+30.2%)	1.0%	$384.68	-12.5%	COM	036752103
DOCS	DOXIMITY INC	400,000 (+122.2%)	$17,712 (+34.5%)	0.9%	$60.22	-6.8%	CL A	26622P107
FMS	FRESENIUS MEDICAL CARE AG	650,000 (+44.4%)	$15,483 (+30.7%)	0.8%	$23.00	—	SPONSORED ADR	358029106
ORIC	ORIC PHARMACEUTICALS INC	1,200,000 (+33.3%)	$9,816 (-9.1%)	0.5%	$7.91	+45.5%	COM	68622P109
ACLX	ARCELLX INC	200,000 (+33.3%)	$13,040 (+5.9%)	0.6%	$73.94	+7.9%	COMMON STOCK	03940C100

Exited Positions (14)

NAMS NEWAMSTERDAM PHARMA COMPANY 1.4%

Value ($000) $28,440 Shares 1,000,000 Est. Cost — Unrealized —

NVO NOVO-NORDISK A S 1.1%

Value ($000) $22,196 Shares 400,000 Est. Cost — Unrealized —

INSM INSMED INC 0.7%

Value ($000) $14,401 Shares 100,000 Est. Cost $33.41 Unrealized +446.2%

PFE PFIZER INC 0.6%

Value ($000) $12,740 Shares 500,000 Est. Cost $23.36 Unrealized +7.2%

MCK MCKESSON CORP 0.6%

Value ($000) $11,588 Shares 15,000 Est. Cost $605.85 Unrealized +34.6%

A AGILENT TECHNOLOGIES INC 0.6%

Value ($000) $11,552 Shares 90,000 Est. Cost $114.89 Unrealized +25.1%

EXAS EXACT SCIENCES CORP 0.5%

Value ($000) $10,942 Shares 200,000 Est. Cost $50.38 Unrealized +59.4%

DYN DYNE THERAPEUTICS INC 0.5%

Value ($000) $10,120 Shares 800,000 Est. Cost $11.41 Unrealized +66.0%

IQV IQVIA HLDGS INC 0.4%

Value ($000) $8,547 Shares 45,000 Est. Cost $181.84 Unrealized +19.7%

ACHC ACADIA HEALTHCARE COMPANY IN 0.4%

Value ($000) $7,428 Shares 300,000 Est. Cost $37.08 Unrealized -49.0%

HOLX HOLOGIC INC 0.3%

Value ($000) $6,749 Shares 100,000 Est. Cost $59.94 Unrealized +21.9%

JNJ JOHNSON & JOHNSON 0.3%

Value ($000) $5,563 Shares 30,000 Est. Cost $169.51 Unrealized +16.2%

PHVS PHARVARIS N V 0.2%

Value ($000) $4,990 Shares 200,000 Est. Cost $22.18 Unrealized +8.6%

ESPR ESPERION THERAPEUTICS INC NE 0.2%

Value ($000) $3,975 Shares 1,500,000 Est. Cost $1.93 Unrealized +67.1%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
NAMS	NEWAMSTERDAM PHARMA COMPANY	1,000,000	$28,440	1.4%	—	—	PUT	N62509109
NVO	NOVO-NORDISK A S	400,000	$22,196	1.1%	—	—	PUT	670100205
INSM	INSMED INC	100,000	$14,401	0.7%	$33.41	+446.2%	PUT	457669307
PFE	PFIZER INC	500,000	$12,740	0.6%	$23.36	+7.2%	—	717081103
MCK	MCKESSON CORP	15,000	$11,588	0.6%	$605.85	+34.6%	—	58155Q103
A	AGILENT TECHNOLOGIES INC	90,000	$11,552	0.6%	$114.89	+25.1%	—	00846U101
EXAS	EXACT SCIENCES CORP	200,000	$10,942	0.5%	$50.38	+59.4%	—	30063P105
DYN	DYNE THERAPEUTICS INC	800,000	$10,120	0.5%	$11.41	+66.0%	—	26818M108
IQV	IQVIA HLDGS INC	45,000	$8,547	0.4%	$181.84	+19.7%	—	46266C105
ACHC	ACADIA HEALTHCARE COMPANY IN	300,000	$7,428	0.4%	$37.08	-49.0%	—	00404A109
HOLX	HOLOGIC INC	100,000	$6,749	0.3%	$59.94	+21.9%	—	436440101
JNJ	JOHNSON & JOHNSON	30,000	$5,563	0.3%	$169.51	+16.2%	—	478160104
PHVS	PHARVARIS N V	200,000	$4,990	0.2%	$22.18	+8.6%	—	N69605108
ESPR	ESPERION THERAPEUTICS INC NE	1,500,000	$3,975	0.2%	$1.93	+67.1%	—	29664W105

Decreased Positions (20)

THC TENET HEALTHCARE CORP 1.0%

Value ($000) $19,872 (-67.4%) Shares 100,000 (-66.7%) Est. Cost $94.23 Unrealized +114.5%

MLYS MINERALYS THERAPEUTICS INC 1.4%

Value ($000) $27,218 (-52.1%) Shares 750,000 (-50.0%) Est. Cost $12.33 Unrealized +225.3%

EHC ENCOMPASS HEALTH CORP 0.5%

Value ($000) $10,614 (-58.2%) Shares 100,000 (-50.0%) Est. Cost $74.91 Unrealized +54.5%

INSM INSMED INC 10.8%

Value ($000) $217,550 (-5.6%) Shares 1,250,000 (-21.9%) Est. Cost $33.41 Unrealized +446.2%

ELAN ELANCO ANIMAL HEALTH INC 0.3%

Value ($000) $5,658 (-64.9%) Shares 250,000 (-68.8%) Est. Cost $14.54 Unrealized +49.7%

TERN TERNS PHARMACEUTICALS INC 0.9%

Value ($000) $17,170 (+140.7%) Shares 425,000 (-55.3%) Est. Cost $6.42 Unrealized +259.8%

CYTK CYTOKINETICS INC 1.6%

Value ($000) $31,770 (-22.9%) Shares 500,000 (-33.3%) Est. Cost $51.92 Unrealized +19.8%

RDNT RADNET INC 0.7%

Value ($000) $14,270 (-37.6%) Shares 200,000 (-33.3%) Est. Cost $57.56 Unrealized +34.1%

BSX BOSTON SCIENTIFIC CORP 1.1%

Value ($000) $21,454 (-26.8%) Shares 225,000 (-25.0%) Est. Cost $63.91 Unrealized +53.4%

OSCR OSCAR HEALTH INC 0.1%

Value ($000) $2,874 (-72.4%) Shares 200,000 (-63.6%) Est. Cost $16.41 Unrealized +5.4%

BTSG BRIGHTSPRING HEALTH SVCS INC 1.4%

Value ($000) $28,088 (-17.4%) Shares 750,000 (-34.8%) Est. Cost $17.09 Unrealized +96.2%

ANRO ALTO NEUROSCIENCE INC 0.3%

Value ($000) $6,675 (+315.1%) Shares 375,000 (-6.3%) Est. Cost $5.58 Unrealized +125.9%

DGX QUEST DIAGNOSTICS INC 0.6%

Value ($000) $13,015 (-19.7%) Shares 75,000 (-11.8%) Est. Cost $172.09 Unrealized +5.8%

NRIX NURIX THERAPEUTICS INC 0.3%

Value ($000) $5,691 (+76.0%) Shares 300,000 (-14.3%) Est. Cost $16.65 Unrealized -13.7%

INSP INSPIRE MED SYS INC 0.3%

Value ($000) $6,917 (-22.3%) Shares 75,000 (-37.5%) Est. Cost $142.33 Unrealized -32.8%

TARS TARSUS PHARMACEUTICALS INC 0.8%

Value ($000) $16,376 (+10.2%) Shares 200,000 (-20.0%) Est. Cost $31.65 Unrealized +135.9%

ARWR ARROWHEAD PHARMACEUTICALS IN 0.3%

Value ($000) $6,639 (-14.4%) Shares 100,000 (-55.6%) Est. Cost $21.98 Unrealized +122.9%

APLS APELLIS PHARMACEUTICALS INC 0.2%

Value ($000) $5,024 (-11.2%) Shares 200,000 (-20.0%) Est. Cost $23.32 Unrealized +0.6%

CRL CHARLES RIV LABS INTL INC 0.4%

Value ($000) $8,977 (-4.4%) Shares 45,000 (-25.0%) Est. Cost $133.35 Unrealized +36.0%

NVST ENVISTA HOLDINGS CORPORATION 0.5%

Value ($000) $10,855 (-3.1%) Shares 500,000 (-9.1%) Est. Cost $20.54 Unrealized -0.1%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
THC	TENET HEALTHCARE CORP	100,000 (-66.7%)	$19,872 (-67.4%)	1.0%	$94.23	+114.5%	COM NEW	88033G407
MLYS	MINERALYS THERAPEUTICS INC	750,000 (-50.0%)	$27,218 (-52.1%)	1.4%	$12.33	+225.3%	COM	603170101
EHC	ENCOMPASS HEALTH CORP	100,000 (-50.0%)	$10,614 (-58.2%)	0.5%	$74.91	+54.5%	COM	29261A100
INSM	INSMED INC	1,250,000 (-21.9%)	$217,550 (-5.6%)	10.8%	$33.41	+446.2%	COM PAR $.01	457669307
ELAN	ELANCO ANIMAL HEALTH INC	250,000 (-68.8%)	$5,658 (-64.9%)	0.3%	$14.54	+49.7%	COM	28414H103
TERN	TERNS PHARMACEUTICALS INC	425,000 (-55.3%)	$17,170 (+140.7%)	0.9%	$6.42	+259.8%	COM	880881107
CYTK	CYTOKINETICS INC	500,000 (-33.3%)	$31,770 (-22.9%)	1.6%	$51.92	+19.8%	CALL	23282W605
RDNT	RADNET INC	200,000 (-33.3%)	$14,270 (-37.6%)	0.7%	$57.56	+34.1%	COM	750491102
BSX	BOSTON SCIENTIFIC CORP	225,000 (-25.0%)	$21,454 (-26.8%)	1.1%	$63.91	+53.4%	COM	101137107
OSCR	OSCAR HEALTH INC	200,000 (-63.6%)	$2,874 (-72.4%)	0.1%	$16.41	+5.4%	CL A	687793109
BTSG	BRIGHTSPRING HEALTH SVCS INC	750,000 (-34.8%)	$28,088 (-17.4%)	1.4%	$17.09	+96.2%	COM	10950A106
ANRO	ALTO NEUROSCIENCE INC	375,000 (-6.3%)	$6,675 (+315.1%)	0.3%	$5.58	+125.9%	COM SHS	02157Q109
DGX	QUEST DIAGNOSTICS INC	75,000 (-11.8%)	$13,015 (-19.7%)	0.6%	$172.09	+5.8%	COM	74834L100
NRIX	NURIX THERAPEUTICS INC	300,000 (-14.3%)	$5,691 (+76.0%)	0.3%	$16.65	-13.7%	COM	67080M103
INSP	INSPIRE MED SYS INC	75,000 (-37.5%)	$6,917 (-22.3%)	0.3%	$142.33	-32.8%	COM	457730109
TARS	TARSUS PHARMACEUTICALS INC	200,000 (-20.0%)	$16,376 (+10.2%)	0.8%	$31.65	+135.9%	COM	87650L103
ARWR	ARROWHEAD PHARMACEUTICALS IN	100,000 (-55.6%)	$6,639 (-14.4%)	0.3%	$21.98	+122.9%	COM	04280A100
APLS	APELLIS PHARMACEUTICALS INC	200,000 (-20.0%)	$5,024 (-11.2%)	0.2%	$23.32	+0.6%	COM	03753U106
CRL	CHARLES RIV LABS INTL INC	45,000 (-25.0%)	$8,977 (-4.4%)	0.4%	$133.35	+36.0%	COM	159864107
NVST	ENVISTA HOLDINGS CORPORATION	500,000 (-9.1%)	$10,855 (-3.1%)	0.5%	$20.54	-0.1%	COM	29415F104

Unchanged Positions (8)

RZLT REZOLUTE INC 0.2%

Value ($000) $4,720 Shares 2,000,000 Est. Cost $4.28 Unrealized +83.0%

EWTX EDGEWISE THERAPEUTICS INC 1.8%

Value ($000) $37,223 Shares 1,500,000 Est. Cost $21.71 Unrealized -7.6%

CYTK CYTOKINETICS INC 4.4%

Value ($000) $88,956 Shares 1,400,000 Est. Cost $51.92 Unrealized +19.8%

LLY ELI LILLY & CO 1.1%

Value ($000) $21,494 Shares 20,000 Est. Cost $773.40 Unrealized +23.6%

ALNY ALNYLAM PHARMACEUTICALS INC 1.2%

Value ($000) $23,859 Shares 60,000 Est. Cost $274.56 Unrealized +61.2%

TENX TENAX THERAPEUTICS INC 0.1%

Value ($000) $2,036 Shares 167,000 Est. Cost $6.41 Unrealized +35.6%

LBRX LB PHARMACEUTICALS INC 0.1%

Value ($000) $2,226 Shares 100,000 Est. Cost $15.87 Unrealized +10.1%

NBIX NEUROCRINE BIOSCIENCES INC 1.1%

Value ($000) $21,275 Shares 150,000 Est. Cost $123.68 Unrealized +17.1%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
RZLT	REZOLUTE INC	2,000,000	$4,720	0.2%	$4.28	+83.0%	COM NEW	76200L309
EWTX	EDGEWISE THERAPEUTICS INC	1,500,000	$37,223	1.8%	$21.71	-7.6%	COM	28036F105
CYTK	CYTOKINETICS INC	1,400,000	$88,956	4.4%	$51.92	+19.8%	COM NEW	23282W605
LLY	ELI LILLY & CO	20,000	$21,494	1.1%	$773.40	+23.6%	COM	532457108
ALNY	ALNYLAM PHARMACEUTICALS INC	60,000	$23,859	1.2%	$274.56	+61.2%	COM	02043Q107
TENX	TENAX THERAPEUTICS INC	167,000	$2,036	0.1%	$6.41	+35.6%	COM NEW	88032L605
LBRX	LB PHARMACEUTICALS INC	100,000	$2,226	0.1%	$15.87	+10.1%	COM SHS	50180M108
NBIX	NEUROCRINE BIOSCIENCES INC	150,000	$21,275	1.1%	$123.68	+17.1%	COM	64125C109