AGIOS PHARMACEUTICALS INC

Ticker: AGIO CUSIP: 00847X104 Class: Common Stock

Note: Option positions (PUT/CALL) are excluded.

New Positions (57)

Increased Positions (74)

ARMISTICE CAPITAL, LLC
Value ($000) $82,640 (+169.5%) Shares 3,036,000 (+297.4%)
ADAR1 Capital Management, LLC
Value ($000) $5,117 (+244.6%) Shares 188,000 (+408.1%)
Vestal Point Capital, LP
Value ($000) $8,847 (+73.5%) Shares 325,000 (+155.9%)
AlphaCentric Advisors LLC
Value ($000) $358 (+77.3%) Shares 13,141 (+114.0%)
ALGERT GLOBAL LLC
Value ($000) $11 (+685.2%) Shares 414,218 (+1058.0%)
Virtus Investment Advisers, LLC
Value ($000) $682 (+31.9%) Shares 25,060 (+94.6%)
Erste Asset Management GmbH
Value ($000) $76,343 (-29.7%) Shares 2,804,900 (+1.4%)
GW&K Investment Management, LLC
Value ($000) $33 (-4.0%) Shares 1,207,301 (+41.5%)
Y-Intercept (Hong Kong) Ltd
Value ($000) $2,173 (+582.5%) Shares 79,831 (+906.4%)
MOORE CAPITAL MANAGEMENT, LP
Value ($000) $4,083 (+84.9%) Shares 150,000 (+172.7%)
D. E. Shaw & Co., Inc.
Value ($000) $50,008 (+238.8%) Shares 1,837,186 (+399.6%)
KENNEDY CAPITAL MANAGEMENT LLC
Value ($000) $1,787 (+80.7%) Shares 65,655 (+166.4%)
PROFUND ADVISORS LLC
Value ($000) $1,085 (+78.9%) Shares 39,850 (+163.8%)
Caption Management, LLC
Value ($000) $2,545 (+262.4%) Shares 93,486 (+434.4%)
TWO SIGMA INVESTMENTS, LP
Value ($000) $8,170 (+241.4%) Shares 300,156 (+403.4%)
Point72 Asset Management, L.P.
Value ($000) $5,444 (+1984.3%) Shares 200,000 (+2973.6%)
Inspire Investing, LLC
Value ($000) $466 (+1.9%) Shares 17,115 (+50.2%)
CITADEL ADVISORS LLC
Value ($000) $36,719 (+85.9%) Shares 1,348,968 (+174.2%)
MILLENNIUM MANAGEMENT LLC
Value ($000) $10,841 (+5249.1%) Shares 398,267 (+7788.0%)
JANE STREET GROUP, LLC
Value ($000) $30,515 (+92.4%) Shares 1,121,050 (+183.7%)

Decreased Positions (64)

TCG Crossover Management, LLC
Value ($000) $32,170 (-44.0%) Shares 1,181,841 (-17.4%)
Rock Springs Capital Management LP
Value ($000) $21,753 (-43.5%) Shares 799,163 (-16.6%)
HighVista Strategies LLC
Value ($000) $4,019 (-48.7%) Shares 147,662 (-24.4%)
Palo Alto Investors LP
Value ($000) $5,784 (-45.7%) Shares 212,499 (-20.0%)
FARALLON CAPITAL MANAGEMENT LLC
Value ($000) $140,442 (-39.5%) Shares 5,159,505 (-10.8%)
BOOTHBAY FUND MANAGEMENT, LLC
Value ($000) $1,015 (-94.9%) Shares 37,291 (-92.5%)
ArrowMark Colorado Holdings LLC
Value ($000) $12,689 (-53.5%) Shares 466,151 (-31.4%)
Ikarian Capital, LLC
Value ($000) $3,144 (-38.3%) Shares 115,489 (-9.0%)
Jump Financial, LLC
Value ($000) $900 (-74.5%) Shares 33,052 (-62.4%)
WELLINGTON MANAGEMENT GROUP LLP
Value ($000) $16,273 (-83.6%) Shares 597,826 (-75.8%)
DEUTSCHE BANK AG\
Value ($000) $3,345 (-91.0%) Shares 122,875 (-86.7%)
OAK RIDGE INVESTMENTS LLC
Value ($000) $545 (-46.6%) Shares 20,004 (-21.2%)
Quarry LP
Value ($000) $82 (-59.3%) Shares 3,000 (-40.0%)
BANK OF AMERICA CORP /DE/
Value ($000) $14,681 (-67.6%) Shares 539,341 (-52.3%)
Pictet Asset Management Holding SA
Value ($000) $5,569 (-47.9%) Shares 205,019 (-24.7%)
TD Asset Management Inc
Value ($000) $1,559 (-69.7%) Shares 57,292 (-55.3%)
UBS Group AG
Value ($000) $3,448 (-64.6%) Shares 126,665 (-47.8%)
AQR CAPITAL MANAGEMENT LLC
Value ($000) $754 (-79.1%) Shares 27,926 (-69.5%)
Hudson Bay Capital Management LP
Value ($000) $2,722 (-44.6%) Shares 100,000 (-18.4%)
Bank of New York Mellon Corp
Value ($000) $5,359 (-50.6%) Shares 196,893 (-27.1%)

Exited Positions (44)