Location: San Francisco, CA
CIK: 0000909661 · Show all filings
Period: Q4 2019 (← Previous) (Next →)
Filing Date: May 15, 2020
Total Value: $14.82B
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| — | ALLERGAN PLC | 7,990,000 | $1.527B | 10.3% | $173.21 | — | — | G0177J108 |
| SPY | SPDR S&P 500 ETF TR | 4,385,000 | $1.411B | 9.5% | — | — | PUT | 78462F103 |
| — | WELLCARE HEALTH PLANS INC | 2,400,000 | $793M | 5.3% | $280.54 | — | — | 94946T106 |
| — | IAC INTERACTIVECORP | 2,066,500 | $515M | 3.5% | $227.15 | — | — | 44919P508 |
| FIS | FIDELITY NATL INFORMATION SV | 3,485,757 | $485M | 3.3% | $85.64 | +38.5% | — | 31620M106 |
| WAB | WABTEC CORP | 5,069,187 | $394M | 2.7% | $77.32 | -7.7% | — | 929740108 |
| ELV | ANTHEM INC | 1,250,000 | $378M | 2.5% | $210.91 | +20.1% | — | 036752103 |
| GOOG | ALPHABET INC | 274,903 | $368M | 2.5% | $52.81 | +21.3% | — | 02079K107 |
| SMH | VANECK VECTORS ETF TRUST | 2,505,000 | $354M | 2.4% | — | — | PUT | 92189F676 |
| MSFT | MICROSOFT CORP | 2,185,790 | $345M | 2.3% | $89.96 | +54.8% | — | 594918104 |
| CHTR | CHARTER COMMUNICATIONS INC N | 683,093 | $331M | 2.2% | $310.85 | +48.0% | — | 16119P108 |
| CI | CIGNA CORP NEW | 1,500,000 | $307M | 2.1% | $180.36 | -7.0% | — | 125523100 |
| IQV | IQVIA HLDGS INC | 1,854,687 | $287M | 1.9% | $109.72 | +33.1% | — | 46266C105 |
| V | VISA INC | 1,522,460 | $286M | 1.9% | $106.64 | +61.8% | — | 92826C839 |
| — | MEDICINES CO | 3,315,000 | $282M | 1.9% | $84.94 | — | — | 584688105 |
| CRM | SALESFORCE COM INC | 1,724,880 | $281M | 1.9% | $154.88 | 0.0% | — | 79466L302 |
| TMO | THERMO FISHER SCIENTIFIC INC | 853,160 | $277M | 1.9% | $298.40 | 0.0% | — | 883556102 |
| — | PLAYA HOTELS & RESORTS NV | 30,606,930 | $257M | 1.7% | $10.52 | — | — | N70544106 |
| PANW | PALO ALTO NETWORKS INC | 1,108,416 | $256M | 1.7% | $36.48 | +3.7% | — | 697435105 |
| EQIX | EQUINIX INC | 416,323 | $243M | 1.6% | $377.50 | +32.8% | — | 29444U700 |
| BABA | ALIBABA GROUP HLDG LTD | 1,132,500 | $240M | 1.6% | $163.44 | — | — | 01609W102 |
| — | ZAYO GROUP HLDGS INC | 6,820,000 | $236M | 1.6% | $33.70 | — | — | 98919V105 |
| ABBV | ABBVIE INC | 2,500,000 | $221M | 1.5% | $59.81 | +8.1% | — | 00287Y109 |
| SHW | SHERWIN WILLIAMS CO | 367,775 | $215M | 1.4% | $132.62 | +36.2% | — | 824348106 |
| META | FACEBOOK INC | 1,030,313 | $211M | 1.4% | $164.54 | +16.9% | — | 30303M102 |
| — | IHS MARKIT LTD | 2,743,550 | $207M | 1.4% | $42.59 | — | — | G47567105 |
| ASND | ASCENDIS PHARMA A S | 1,279,000 | $178M | 1.2% | $66.74 | — | — | 04351P101 |
| SPGI | S&P GLOBAL INC | 640,382 | $175M | 1.2% | $182.65 | +35.2% | — | 78409V104 |
| GD | GENERAL DYNAMICS CORP | 981,365 | $173M | 1.2% | $167.23 | -6.8% | — | 369550108 |
| IOVA | IOVANCE BIOTHERAPEUTICS INC | 6,250,000 | $173M | 1.2% | $12.45 | +82.7% | — | 462260100 |
| ALNY | ALNYLAM PHARMACEUTICALS INC | 1,450,000 | $167M | 1.1% | $85.60 | +16.5% | — | 02043Q107 |
| — | MYOKARDIA INC | 2,050,000 | $149M | 1.0% | $47.32 | — | — | 62857M105 |
| EXEL | EXELIXIS INC | 7,500,000 | $132M | 0.9% | $17.68 | -4.1% | — | 30161Q104 |
| TRU | TRANSUNION | 1,527,771 | $131M | 0.9% | $57.98 | +39.5% | — | 89400J107 |
| ENTA | ENANTA PHARMACEUTICALS INC | 1,750,000 | $108M | 0.7% | $61.14 | +1.4% | — | 29251M106 |
| — | ACCELERON PHARMA INC | 2,000,000 | $106M | 0.7% | $43.22 | — | — | 00434H108 |
| — | BROADMARK RLTY CAP INC | 7,174,613 | $91.48M | 0.6% | $12.75 | — | — | 11135B100 |
| — | BRISTOL MYERS SQUIBB CO | 30,374,950 | $91.43M | 0.6% | $3.01 | — | — | 110122157 |
| EFX | EQUIFAX INC | 652,189 | $91.39M | 0.6% | $108.99 | +21.2% | — | 294429105 |
| — | ZOGENIX INC | 1,750,000 | $91.23M | 0.6% | $37.78 | — | — | 98978L204 |
| — | AMARIN CORP PLC | 4,125,000 | $88.44M | 0.6% | $14.58 | — | — | 023111206 |
| — | ANIXTER INTL INC | 917,893 | $84.54M | 0.6% | $92.10 | — | — | 035290105 |
| — | ZYMEWORKS INC | 1,700,000 | $77.28M | 0.5% | $15.82 | — | — | 98985W102 |
| — | QIAGEN NV | 2,154,000 | $72.81M | 0.5% | $33.80 | — | — | N72482123 |
| GRFS | GRIFOLS S A | 3,113,222 | $72.51M | 0.5% | $20.53 | — | — | 398438408 |
| — | AUDENTES THERAPEUTICS INC | 1,190,000 | $71.21M | 0.5% | $59.84 | — | — | 05070R104 |
| AGIO | AGIOS PHARMACEUTICALS INC | 1,250,000 | $59.69M | 0.4% | $37.79 | 0.0% | — | 00847X104 |
| — | GLOBAL BLOOD THERAPEUTICS IN | 750,000 | $59.62M | 0.4% | $45.61 | — | — | 37890U108 |
| — | CHEMOCENTRYX INC | 1,500,000 | $59.33M | 0.4% | $12.09 | — | — | 16383L106 |
| — | DECIPHERA PHARMACEUTICALS IN | 950,000 | $59.13M | 0.4% | $39.90 | — | — | 24344T101 |
| — | FIBROGEN INC | 1,350,000 | $57.9M | 0.4% | $41.47 | — | — | 31572Q808 |
| — | RA PHARMACEUTICALS INC | 1,188,100 | $55.76M | 0.4% | $46.93 | — | — | 74933V108 |
| CVS | CVS HEALTH CORP | 750,000 | $55.72M | 0.4% | $54.97 | +5.1% | — | 126650100 |
| — | MOMENTA PHARMACEUTICALS INC | 2,750,000 | $54.26M | 0.4% | $19.73 | — | — | 60877T100 |
| SRPT | SAREPTA THERAPEUTICS INC | 400,000 | $51.62M | 0.3% | — | — | CALL | 803607100 |
| — | ARQULE INC | 2,520,000 | $50.3M | 0.3% | $19.96 | — | — | 04269E107 |
| — | PTC THERAPEUTICS INC | 39,676,000 | $45.85M | 0.3% | $1.13 | — | — | 69366JAB7 |
| AXSM | AXSOME THERAPEUTICS INC | 442,222 | $45.71M | 0.3% | $27.10 | +49.0% | — | 05464T104 |
| — | KARUNA THERAPEUTICS INC | 600,000 | $45.2M | 0.3% | $75.34 | — | — | 48576A100 |
| FATE | FATE THERAPEUTICS INC | 2,250,000 | $44.03M | 0.3% | $13.72 | +15.8% | — | 31189P102 |
| — | PROGENICS PHARMACEUTICALS IN | 8,250,000 | $41.99M | 0.3% | $6.28 | — | — | 743187106 |
| — | RADIUS HEALTH INC | 2,054,486 | $41.42M | 0.3% | $39.28 | — | — | 750469207 |
| — | TRICIDA INC | 1,000,000 | $37.74M | 0.3% | $34.30 | — | — | 89610F101 |
| — | CARA THERAPEUTICS INC | 2,300,000 | $37.05M | 0.3% | $19.47 | — | — | 140755109 |
| — | SAGE THERAPEUTICS INC | 500,000 | $36.09M | 0.2% | $120.01 | — | — | 78667J108 |
| PTCT | PTC THERAPEUTICS INC | 726,986 | $34.92M | 0.2% | $39.96 | +6.3% | — | 69366J200 |
| — | KARYOPHARM THERAPEUTICS INC | 24,000,000 | $34.43M | 0.2% | $1.43 | — | — | 48576UAA4 |
| — | ZEALAND PHARMA A S | 1,009,800 | $33.52M | 0.2% | $18.16 | — | — | 98920Y304 |
| — | CYPRESS SEMICONDUCTOR CORP | 18,645,000 | $32.44M | 0.2% | $1.75 | — | — | 232806AM1 |
| — | MELLANOX TECHNOLOGIES LTD | 270,000 | $31.64M | 0.2% | $113.67 | — | — | M51363113 |
| — | AVROBIO INC | 1,550,000 | $31.2M | 0.2% | $21.90 | — | — | 05455M100 |
| — | TIFFANY & CO NEW | 225,000 | $30.07M | 0.2% | $133.65 | — | — | 886547108 |
| — | INSTRUCTURE INC | 620,000 | $29.89M | 0.2% | $48.21 | — | — | 45781U103 |
| — | INVITAE CORP | 1,750,000 | $28.23M | 0.2% | $20.62 | — | — | 46185L103 |
| VCYT | VERACYTE INC | 1,000,000 | $27.92M | 0.2% | $26.03 | -0.6% | — | 92337F107 |
| — | STEMLINE THERAPEUTICS INC | 2,350,000 | $24.98M | 0.2% | $11.97 | — | — | 85858C107 |
| RC | READY CAP CORP | 1,617,170 | $24.94M | 0.2% | $13.85 | — | — | 75574U101 |
| — | QUOTIENT LTD | 2,500,000 | $23.77M | 0.2% | $7.28 | — | — | G73268107 |
| — | INTERCEPT PHARMACEUTICALS IN | 17,500,000 | $23.15M | 0.2% | $1.32 | — | — | 45845PAB4 |
| — | MIRATI THERAPEUTICS INC | 175,000 | $22.55M | 0.2% | $42.97 | — | — | 60468T105 |
| — | PRINCIPIA BIOPHARMA INC | 400,000 | $21.91M | 0.1% | $54.78 | — | — | 74257L108 |
| SVRA | SAVARA INC | 4,825,086 | $21.62M | 0.1% | $5.45 | -77.9% | — | 805111101 |
| — | AMARIN CORP PLC | 1,000,000 | $21.44M | 0.1% | $14.58 | — | CALL | 023111206 |
| CRSP | CRISPR THERAPEUTICS AG | 350,000 | $21.32M | 0.1% | $34.31 | +59.1% | — | H17182108 |
| — | WRIGHT MED GROUP N V | 690,000 | $21.03M | 0.1% | $30.48 | — | — | N96617118 |
| HRTX | HERON THERAPEUTICS INC | 875,000 | $20.56M | 0.1% | $22.12 | 0.0% | — | 427746102 |
| — | CYPRESS SEMICONDUCTOR CORP | 840,000 | $19.6M | 0.1% | $23.34 | — | — | 232806109 |
| GEN | NORTONLIFELOCK INC | 720,000 | $18.37M | 0.1% | $12.38 | 0.0% | — | 668771108 |
| — | SPRINT CORPORATION | 3,200,000 | $16.67M | 0.1% | $6.43 | — | — | 85207U105 |
| — | EIGER BIOPHARMACEUTICALS INC | 1,094,559 | $16.31M | 0.1% | $10.56 | — | — | 28249U105 |
| PACB | PACIFIC BIOSCIENCES CALIF IN | 3,000,000 | $15.42M | 0.1% | $5.08 | 0.0% | — | 69404D108 |
| — | REATA PHARMACEUTICALS INC | 75,000 | $15.33M | 0.1% | $81.93 | — | — | 75615P103 |
| APLS | APELLIS PHARMACEUTICALS INC | 500,000 | $15.31M | 0.1% | $27.68 | 0.0% | — | 03753U106 |
| — | LIVONGO HEALTH INC | 600,000 | $15.04M | 0.1% | $25.06 | — | — | 539183103 |
| XGN | EXAGEN INC | 577,699 | $14.67M | 0.1% | $16.64 | +6.9% | — | 30068X103 |
| QURE | UNIQURE NV | 200,000 | $14.33M | 0.1% | $59.35 | -7.5% | — | N90064101 |
| — | CLOVIS ONCOLOGY INC | 18,801,000 | $12.08M | 0.1% | $0.72 | — | — | 189464AC4 |
| — | LOGMEIN INC | 130,241 | $11.17M | 0.1% | $85.74 | — | — | 54142L109 |
| PTGX | PROTAGONIST THERAPEUTICS INC | 1,500,000 | $10.57M | 0.1% | $12.36 | -19.7% | — | 74366E102 |
| — | OPTINOSE INC | 900,000 | $8.298M | 0.1% | $9.22 | — | — | 68404V100 |
| RCKT | ROCKET PHARMACEUTICALS INC | 354,082 | $8.059M | 0.1% | $16.70 | 0.0% | — | 77313F106 |
| — | SANOFI | 9,195,584 | $7.91M | 0.1% | $0.46 | — | — | 80105N113 |
| GOSS | GOSSAMER BIO INC | 500,000 | $7.815M | 0.1% | $20.29 | -0.7% | — | 38341P102 |
| DMTKQ | DERMTECH INC | 615,385 | $7.631M | 0.1% | $5.60 | — | — | 24984K105 |
| — | ABEONA THERAPEUTICS INC | 2,000,000 | $6.54M | 0.0% | $3.27 | — | — | 00289Y107 |
| ARWR | ARROWHEAD PHARMACEUTICALS IN | 100,000 | $6.343M | 0.0% | $14.59 | +240.0% | — | 04280A100 |
| — | PHASEBIO PHARMACEUTICALS INC | 1,000,000 | $6.11M | 0.0% | $11.32 | — | — | 717224109 |
| — | RADIUS HEALTH INC | 6,750,000 | $5.787M | 0.0% | $0.85 | — | — | 750469AA6 |
| — | OYSTER POINT PHARMA INC | 230,800 | $5.641M | 0.0% | $24.44 | — | — | 69242L106 |
| — | ATARA BIOTHERAPEUTICS INC | 334,706 | $5.513M | 0.0% | $16.47 | — | — | 046513107 |
| XRX | XEROX HOLDINGS CORP | 130,000 | $4.793M | 0.0% | $34.97 | 0.0% | — | 98421M106 |
| OPK | OPKO HEALTH INC | 2,500,000 | $3.675M | 0.0% | $1.67 | 0.0% | — | 68375N103 |
| — | BROADMARK RLTY CAP INC | 7,174,613 | $2.726M | 0.0% | $0.38 | — | — | 11135B118 |
| — | ZAFGEN INC | 1,808,360 | $2.007M | 0.0% | $9.98 | — | — | 98885E103 |
| — | APTINYX INC | 408,549 | $1.397M | 0.0% | $24.69 | — | — | 03836N103 |
| — | CYCLERION THERAPEUTICS INC | 350,000 | $952K | 0.0% | $14.81 | — | — | 23255M105 |