Bellevue Group AG Diversified Active

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
FOLD	AMICUS THERAPEUTICS INC	10,735,195	$152,869	2.9%	$9.82	0.0%	COM	03152W109
VRDN	VIRIDIAN THERAPEUTICS INC	4,358,527	$135,637	2.6%	$27.43	0.0%	COM	92790C104
NUVL	NUVALENT INC	1,037,468	$104,359	2.0%	$98.60	0.0%	COM	670703107
VERA	VERA THERAPEUTICS INC	1,698,152	$85,994	1.6%	$35.52	0.0%	CL A	92337R101
JBIO	JADE BIOSCIENCES INC	3,341,103	$51,553	1.0%	$11.73	0.0%	COM NEW	008064206
MAZE	MAZE THERAPEUTICS INC	887,708	$36,778	0.7%	$34.37	0.0%	COM	578784100
TNGX	TANGO THERAPEUTICS INC	3,927,670	$34,799	0.7%	$8.62	0.0%	COM	87583X109
MDLN	MEDLINE INC	117,720	$4,944	0.1%	$42.23	0.0%	COM CL A	58507V107
ROIV	ROIVANT SCIENCES LTD	108,039	$2,344	0.0%	$19.73	0.0%	SHS	G76279101
CMPS	COMPASS PATHWAYS PLC	142,243	$981	0.0%	$6.90	—	SPONSORED ADS	20451W101
BLLN	BILLIONTOONE INC	10,589	$867	0.0%	$101.40	0.0%	CL A	090168105
ARWR	ARROWHEAD PHARMACEUTICALS IN	11,550	$767	0.0%	$49.01	0.0%	COM	04280A100
BABA	ALIBABA GROUP HLDG LTD	4,700	$689	0.0%	$146.58	—	SPONSORED ADS	01609W102
ANET	ARISTA NETWORKS INC	4,800	$629	0.0%	$137.66	0.0%	COM SHS	040413205
MA	MASTERCARD INCORPORATED	1,100	$628	0.0%	$558.95	0.0%	CL A	57636Q104
CSCO	CISCO SYS INC	8,000	$616	0.0%	$73.79	0.0%	COM	17275R102
PG	PROCTER AND GAMBLE CO	3,900	$559	0.0%	$147.17	0.0%	COM	742718109
V	VISA INC	1,400	$491	0.0%	$340.38	0.0%	COM CL A	92826C839
BLK	BLACKROCK INC	450	$482	0.0%	$1089.41	0.0%	COM	09290D101
LULU	LULULEMON ATHLETICA INC	2,240	$465	0.0%	$181.15	0.0%	COM	550021109
PLTR	PALANTIR TECHNOLOGIES INC	2,500	$444	0.0%	$181.03	0.0%	CL A	69608A108
ADBE	ADOBE INC	1,200	$420	0.0%	$340.09	0.0%	COM	00724F101
ACN	ACCENTURE PLC IRELAND	1,500	$402	0.0%	$254.06	0.0%	SHS CLASS A	G1151C101
JD	JD.COM INC	11,000	$316	0.0%	$28.70	—	SPON ADS CL A	47215P106
CRNX	CRINETICS PHARMACEUTICALS IN	4,040	$188	0.0%	$44.52	0.0%	COM	22663K107
IDYA	IDEAYA BIOSCIENCES INC	4,942	$171	0.0%	$31.88	0.0%	COM	45166A102
TVTX	TRAVERE THERAPEUTICS INC	3,827	$146	0.0%	$32.52	0.0%	COM	89422G107
CGON	CG ONCOLOGY INC	3,095	$129	0.0%	$41.38	0.0%	COM	156944100
DNLI	DENALI THERAPEUTICS INC	7,138	$118	0.0%	$16.88	0.0%	COM	24823R105
APLS	APELLIS PHARMACEUTICALS INC	4,210	$106	0.0%	$23.46	0.0%	COM	03753U106
CRSP	CRISPR THERAPEUTICS AG	1,880	$99	0.0%	$59.89	0.0%	NAMEN AKT	H17182108
OLMA	OLEMA PHARMACEUTICALS INC	3,902	$98	0.0%	$17.79	0.0%	COM	68062P106
TRVI	TREVI THERAPEUTICS INC	7,603	$95	0.0%	$11.56	0.0%	COM	89532M101
TYRA	TYRA BIOSCIENCES INC	3,143	$83	0.0%	$18.37	0.0%	COM	90240B106
ORIC	ORIC PHARMACEUTICALS INC	9,706	$79	0.0%	$11.51	0.0%	COM	68622P109
RARE	ULTRAGENYX PHARMACEUTICAL IN	2,580	$59	0.0%	$32.88	0.0%	COM	90400D108
NTLA	INTELLIA THERAPEUTICS INC	2,978	$27	0.0%	$13.77	0.0%	COM	45826J105

Increased Positions (45)

VRTX VERTEX PHARMACEUTICALS INC 5.9%

Value ($000) $308,793 (+55.9%) Shares 681,120 (+34.7%) Est. Cost $289.65 Unrealized +48.8%

KRYS KRYSTAL BIOTECH INC 1.9%

Value ($000) $101,161 (+43577.9%) Shares 410,323 (+31174.6%) Est. Cost $210.08 Unrealized +0.2%

RNA AVIDITY BIOSCIENCES INC 3.6%

Value ($000) $189,772 (+102.3%) Shares 2,630,969 (+22.2%) Est. Cost $44.82 Unrealized +44.1%

SRRK SCHOLAR ROCK HLDG CORP 3.4%

Value ($000) $178,693 (+47.9%) Shares 4,056,592 (+25.0%) Est. Cost $25.47 Unrealized +47.3%

GKOS GLAUKOS CORP 0.6%

Value ($000) $29,575 (+548.5%) Shares 261,935 (+368.4%) Est. Cost $95.06 Unrealized +0.5%

EW EDWARDS LIFESCIENCES CORP 1.7%

Value ($000) $88,924 (+27.5%) Shares 1,043,096 (+16.3%) Est. Cost $76.43 Unrealized +7.4%

IDXX IDEXX LABS INC 1.2%

Value ($000) $63,958 (+30.7%) Shares 94,539 (+23.4%) Est. Cost $425.27 Unrealized +60.1%

JNJ JOHNSON & JOHNSON 0.5%

Value ($000) $26,241 (+89.2%) Shares 126,800 (+69.5%) Est. Cost $170.87 Unrealized +15.3%

DHR DANAHER CORPORATION 0.8%

Value ($000) $44,555 (+37.1%) Shares 194,633 (+18.8%) Est. Cost $192.32 Unrealized +14.2%

MRK MERCK & CO INC 0.2%

Value ($000) $9,696 (+232.6%) Shares 92,117 (+165.2%) Est. Cost $94.35 Unrealized -1.2%

CLDX CELLDEX THERAPEUTICS INC NEW 1.9%

Value ($000) $98,256 (+6.8%) Shares 3,617,669 (+1.7%) Est. Cost $30.41 Unrealized -13.4%

INSP INSPIRE MED SYS INC 0.2%

Value ($000) $9,293 (+113.6%) Shares 100,761 (+71.8%) Est. Cost $131.09 Unrealized -27.0%

CVS CVS HEALTH CORP 0.2%

Value ($000) $8,655 (+124.2%) Shares 109,058 (+113.0%) Est. Cost $72.21 Unrealized +9.0%

DXCM DEXCOM INC 1.1%

Value ($000) $56,242 (+6.3%) Shares 847,405 (+7.8%) Est. Cost $98.21 Unrealized -34.2%

WAY WAYSTAR HLDG CORP 0.2%

Value ($000) $7,917 (+60.7%) Shares 241,734 (+86.1%) Est. Cost $28.72 Unrealized +24.0%

ADPT ADAPTIVE BIOTECHNOLOGIES COR 0.1%

Value ($000) $4,841 (+92.1%) Shares 298,090 (+76.9%) Est. Cost $13.98 Unrealized +16.7%

AVTR AVANTOR INC 0.1%

Value ($000) $3,166 (+145.4%) Shares 276,266 (+167.3%) Est. Cost $12.52 Unrealized -1.7%

AMGN AMGEN INC 0.1%

Value ($000) $6,052 (+43.1%) Shares 18,489 (+23.4%) Est. Cost $277.28 Unrealized +13.9%

TXG 10X GENOMICS INC 0.1%

Value ($000) $5,253 (+43.2%) Shares 322,060 (+2.6%) Est. Cost $60.98 Unrealized -75.2%

BMY BRISTOL-MYERS SQUIBB CO 0.1%

Value ($000) $3,618 (+68.5%) Shares 67,082 (+40.9%) Est. Cost $45.80 Unrealized +3.8%

PFE PFIZER INC 0.0%

Value ($000) $1,415 (+369.7%) Shares 56,847 (+380.7%) Est. Cost $25.24 Unrealized -0.8%

GILD GILEAD SCIENCES INC 0.1%

Value ($000) $6,475 (+16.9%) Shares 52,752 (+5.7%) Est. Cost $71.47 Unrealized +69.1%

BBNX BETA BIONICS INC 0.0%

Value ($000) $2,203 (+72.4%) Shares 72,285 (+12.4%) Est. Cost $19.54 Unrealized +36.7%

BKD BROOKDALE SR LIVING INC 0.0%

Value ($000) $1,807 (+103.8%) Shares 167,444 (+60.0%) Est. Cost $8.45 Unrealized +16.4%

UNH UNITEDHEALTH GROUP INC 1.1%

Value ($000) $57,825 (-1.5%) Shares 175,169 (+3.0%) Est. Cost $354.01 Unrealized -4.7%

NAMS NEWAMSTERDAM PHARMA COMPANY 0.0%

Value ($000) $1,275 (+206.8%) Shares 36,336 (+148.7%) Est. Cost $29.81 Unrealized +22.1%

BNTX BIONTECH SE 0.1%

Value ($000) $4,165 (+24.4%) Shares 43,755 (+28.9%) Est. Cost $106.12 Unrealized —

UTHR UNITED THERAPEUTICS CORP DEL 0.0%

Value ($000) $1,898 (+71.5%) Shares 3,895 (+47.5%) Est. Cost $378.00 Unrealized +23.2%

BBIO BRIDGEBIO PHARMA INC 0.0%

Value ($000) $1,844 (+74.4%) Shares 24,111 (+18.4%) Est. Cost $35.61 Unrealized +84.3%

NVDA NVIDIA CORPORATION 0.0%

Value ($000) $734 (+460.0%) Shares 3,933 (+460.3%) Est. Cost $170.24 Unrealized +9.3%

MDGL MADRIGAL PHARMACEUTICALS INC 0.0%

Value ($000) $1,679 (+53.0%) Shares 2,884 (+20.5%) Est. Cost $344.12 Unrealized +48.4%

MSFT MICROSOFT CORP 0.0%

Value ($000) $620 (+489.7%) Shares 1,282 (+531.5%) Est. Cost $480.35 Unrealized +4.2%

AAPL APPLE INC 0.0%

Value ($000) $903 (+120.3%) Shares 3,320 (+106.3%) Est. Cost $247.62 Unrealized +8.4%

CYTK CYTOKINETICS INC 0.0%

Value ($000) $586 (+407.9%) Shares 9,225 (+339.3%) Est. Cost $56.66 Unrealized +9.8%

AMZN AMAZON COM INC 0.0%

Value ($000) $817 (+105.4%) Shares 3,541 (+95.4%) Est. Cost $223.16 Unrealized +2.5%

GOOGL ALPHABET INC 0.0%

Value ($000) $647 (+145.8%) Shares 2,066 (+90.9%) Est. Cost $228.46 Unrealized +25.0%

PTCT PTC THERAPEUTICS INC 0.0%

Value ($000) $514 (+230.9%) Shares 6,763 (+167.3%) Est. Cost $61.50 Unrealized +18.2%

PRCT PROCEPT BIOROBOTICS CORP 0.3%

Value ($000) $16,215 (-2.0%) Shares 515,430 (+11.2%) Est. Cost $38.47 Unrealized -13.8%

CORT CORCEPT THERAPEUTICS INC 0.0%

Value ($000) $365 (+258.1%) Shares 10,495 (+755.3%) Est. Cost $77.82 Unrealized +0.9%

META META PLATFORMS INC 0.0%

Value ($000) $528 (+79.8%) Shares 800 (+100.0%) Est. Cost $705.28 Unrealized -5.4%

ICLR ICON PLC 0.1%

Value ($000) $4,475 (+5.5%) Shares 24,560 (+1.3%) Est. Cost $167.50 Unrealized +6.3%

DOCS DOXIMITY INC 0.0%

Value ($000) $523 (-26.2%) Shares 11,817 (+21.9%) Est. Cost $39.64 Unrealized +41.6%

GH GUARDANT HEALTH INC 0.0%

Value ($000) $307 (+151.5%) Shares 3,004 (+53.8%) Est. Cost $66.66 Unrealized +34.2%

CERT CERTARA INC 0.0%

Value ($000) $876 (+20.6%) Shares 99,442 (+67.3%) Est. Cost $14.20 Unrealized -27.5%

RPRX ROYALTY PHARMA PLC 0.0%

Value ($000) $510 (+11.6%) Shares 13,201 (+1.9%) Est. Cost $36.24 Unrealized +5.2%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
VRTX	VERTEX PHARMACEUTICALS INC	681,120 (+34.7%)	$308,793 (+55.9%)	5.9%	$289.65	+48.8%	COM	92532F100
KRYS	KRYSTAL BIOTECH INC	410,323 (+31174.6%)	$101,161 (+43577.9%)	1.9%	$210.08	+0.2%	COM	501147102
RNA	AVIDITY BIOSCIENCES INC	2,630,969 (+22.2%)	$189,772 (+102.3%)	3.6%	$44.82	+44.1%	COM	05370A108
SRRK	SCHOLAR ROCK HLDG CORP	4,056,592 (+25.0%)	$178,693 (+47.9%)	3.4%	$25.47	+47.3%	COM	80706P103
GKOS	GLAUKOS CORP	261,935 (+368.4%)	$29,575 (+548.5%)	0.6%	$95.06	+0.5%	COM	377322102
EW	EDWARDS LIFESCIENCES CORP	1,043,096 (+16.3%)	$88,924 (+27.5%)	1.7%	$76.43	+7.4%	COM	28176E108
IDXX	IDEXX LABS INC	94,539 (+23.4%)	$63,958 (+30.7%)	1.2%	$425.27	+60.1%	COM	45168D104
JNJ	JOHNSON & JOHNSON	126,800 (+69.5%)	$26,241 (+89.2%)	0.5%	$170.87	+15.3%	COM	478160104
DHR	DANAHER CORPORATION	194,633 (+18.8%)	$44,555 (+37.1%)	0.8%	$192.32	+14.2%	COM	235851102
MRK	MERCK & CO INC	92,117 (+165.2%)	$9,696 (+232.6%)	0.2%	$94.35	-1.2%	COM	58933Y105
CLDX	CELLDEX THERAPEUTICS INC NEW	3,617,669 (+1.7%)	$98,256 (+6.8%)	1.9%	$30.41	-13.4%	COM NEW	15117B202
INSP	INSPIRE MED SYS INC	100,761 (+71.8%)	$9,293 (+113.6%)	0.2%	$131.09	-27.0%	COM	457730109
CVS	CVS HEALTH CORP	109,058 (+113.0%)	$8,655 (+124.2%)	0.2%	$72.21	+9.0%	COM	126650100
DXCM	DEXCOM INC	847,405 (+7.8%)	$56,242 (+6.3%)	1.1%	$98.21	-34.2%	COM	252131107
WAY	WAYSTAR HLDG CORP	241,734 (+86.1%)	$7,917 (+60.7%)	0.2%	$28.72	+24.0%	COM	946784105
ADPT	ADAPTIVE BIOTECHNOLOGIES COR	298,090 (+76.9%)	$4,841 (+92.1%)	0.1%	$13.98	+16.7%	COM	00650F109
AVTR	AVANTOR INC	276,266 (+167.3%)	$3,166 (+145.4%)	0.1%	$12.52	-1.7%	COM	05352A100
AMGN	AMGEN INC	18,489 (+23.4%)	$6,052 (+43.1%)	0.1%	$277.28	+13.9%	COM	031162100
TXG	10X GENOMICS INC	322,060 (+2.6%)	$5,253 (+43.2%)	0.1%	$60.98	-75.2%	CL A COM	88025U109
BMY	BRISTOL-MYERS SQUIBB CO	67,082 (+40.9%)	$3,618 (+68.5%)	0.1%	$45.80	+3.8%	COM	110122108
PFE	PFIZER INC	56,847 (+380.7%)	$1,415 (+369.7%)	0.0%	$25.24	-0.8%	COM	717081103
GILD	GILEAD SCIENCES INC	52,752 (+5.7%)	$6,475 (+16.9%)	0.1%	$71.47	+69.1%	COM	375558103
BBNX	BETA BIONICS INC	72,285 (+12.4%)	$2,203 (+72.4%)	0.0%	$19.54	+36.7%	COM	08659B102
BKD	BROOKDALE SR LIVING INC	167,444 (+60.0%)	$1,807 (+103.8%)	0.0%	$8.45	+16.4%	COM	112463104
UNH	UNITEDHEALTH GROUP INC	175,169 (+3.0%)	$57,825 (-1.5%)	1.1%	$354.01	-4.7%	COM	91324P102
NAMS	NEWAMSTERDAM PHARMA COMPANY	36,336 (+148.7%)	$1,275 (+206.8%)	0.0%	$29.81	+22.1%	ORDINARY SHARES	N62509109
BNTX	BIONTECH SE	43,755 (+28.9%)	$4,165 (+24.4%)	0.1%	$106.12	—	SPONSORED ADS	09075V102
UTHR	UNITED THERAPEUTICS CORP DEL	3,895 (+47.5%)	$1,898 (+71.5%)	0.0%	$378.00	+23.2%	COM	91307C102
BBIO	BRIDGEBIO PHARMA INC	24,111 (+18.4%)	$1,844 (+74.4%)	0.0%	$35.61	+84.3%	COM	10806X102
NVDA	NVIDIA CORPORATION	3,933 (+460.3%)	$734 (+460.0%)	0.0%	$170.24	+9.3%	COM	67066G104
MDGL	MADRIGAL PHARMACEUTICALS INC	2,884 (+20.5%)	$1,679 (+53.0%)	0.0%	$344.12	+48.4%	COM	558868105
MSFT	MICROSOFT CORP	1,282 (+531.5%)	$620 (+489.7%)	0.0%	$480.35	+4.2%	COM	594918104
AAPL	APPLE INC	3,320 (+106.3%)	$903 (+120.3%)	0.0%	$247.62	+8.4%	COM	037833100
CYTK	CYTOKINETICS INC	9,225 (+339.3%)	$586 (+407.9%)	0.0%	$56.66	+9.8%	COM NEW	23282W605
AMZN	AMAZON COM INC	3,541 (+95.4%)	$817 (+105.4%)	0.0%	$223.16	+2.5%	COM	023135106
GOOGL	ALPHABET INC	2,066 (+90.9%)	$647 (+145.8%)	0.0%	$228.46	+25.0%	CAP STK CL A	02079K305
PTCT	PTC THERAPEUTICS INC	6,763 (+167.3%)	$514 (+230.9%)	0.0%	$61.50	+18.2%	COM	69366J200
PRCT	PROCEPT BIOROBOTICS CORP	515,430 (+11.2%)	$16,215 (-2.0%)	0.3%	$38.47	-13.8%	COM	74276L105
CORT	CORCEPT THERAPEUTICS INC	10,495 (+755.3%)	$365 (+258.1%)	0.0%	$77.82	+0.9%	COM	218352102
META	META PLATFORMS INC	800 (+100.0%)	$528 (+79.8%)	0.0%	$705.28	-5.4%	CL A	30303M102
ICLR	ICON PLC	24,560 (+1.3%)	$4,475 (+5.5%)	0.1%	$167.50	+6.3%	SHS	G4705A100
DOCS	DOXIMITY INC	11,817 (+21.9%)	$523 (-26.2%)	0.0%	$39.64	+41.6%	CL A	26622P107
GH	GUARDANT HEALTH INC	3,004 (+53.8%)	$307 (+151.5%)	0.0%	$66.66	+34.2%	COM	40131M109
CERT	CERTARA INC	99,442 (+67.3%)	$876 (+20.6%)	0.0%	$14.20	-27.5%	COM	15687V109
RPRX	ROYALTY PHARMA PLC	13,201 (+1.9%)	$510 (+11.6%)	0.0%	$36.24	+5.2%	SHS CLASS A	G7709Q104

Exited Positions (9)

AGIO AGIOS PHARMACEUTICALS INC 2.8%

Value ($000) $149,110 Shares 3,714,736 Est. Cost $49.34 Unrealized -28.9%

— AKERO THERAPEUTICS INC 2.1%

Value ($000) $113,445 Shares 2,389,314 Est. Cost $45.62 Unrealized —

BHVN BIOHAVEN LTD 0.8%

Value ($000) $42,071 Shares 2,802,853 Est. Cost $30.67 Unrealized -59.6%

HOLX HOLOGIC INC 0.3%

Value ($000) $16,730 Shares 247,886 Est. Cost $59.24 Unrealized +23.3%

MGNX MACROGENICS INC 0.3%

Value ($000) $16,666 Shares 9,919,992 Est. Cost $16.28 Unrealized -90.3%

BAX BAXTER INTL INC 0.0%

Value ($000) $1,550 Shares 68,084 Est. Cost $32.18 Unrealized -37.8%

BIDU BAIDU INC 0.0%

Value ($000) $264 Shares 2,000 Est. Cost $105.28 Unrealized —

MLTX MOONLAKE IMMUNOTHERAPEUTICS 0.0%

Value ($000) $251 Shares 35,052 Est. Cost $52.30 Unrealized -77.4%

— MERUS N V 0.0%

Value ($000) $78 Shares 825 Est. Cost $18.01 Unrealized —

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
AGIO	AGIOS PHARMACEUTICALS INC	3,714,736	$149,110	2.8%	$49.34	-28.9%	—	00847X104
—	AKERO THERAPEUTICS INC	2,389,314	$113,445	2.1%	$45.62	—	—	00973Y108
BHVN	BIOHAVEN LTD	2,802,853	$42,071	0.8%	$30.67	-59.6%	—	G1110E107
HOLX	HOLOGIC INC	247,886	$16,730	0.3%	$59.24	+23.3%	—	436440101
MGNX	MACROGENICS INC	9,919,992	$16,666	0.3%	$16.28	-90.3%	—	556099109
BAX	BAXTER INTL INC	68,084	$1,550	0.0%	$32.18	-37.8%	—	071813109
BIDU	BAIDU INC	2,000	$264	0.0%	$105.28	—	—	056752108
MLTX	MOONLAKE IMMUNOTHERAPEUTICS	35,052	$251	0.0%	$52.30	-77.4%	—	61559X104
—	MERUS N V	825	$78	0.0%	$18.01	—	—	N5749R100

Decreased Positions (79)

RVMD REVOLUTION MEDICINES INC 7.6%

Value ($000) $398,706 (+53.2%) Shares 5,005,719 (-10.2%) Est. Cost $32.29 Unrealized +103.1%

INCY INCYTE CORP 0.0%

Value ($000) $471 (-99.6%) Shares 4,773 (-99.7%) Est. Cost $80.18 Unrealized +20.7%

BEAM BEAM THERAPEUTICS INC 0.1%

Value ($000) $3,091 (-95.6%) Shares 111,510 (-96.1%) Est. Cost $33.72 Unrealized -24.3%

SYK STRYKER CORPORATION 2.4%

Value ($000) $126,732 (-24.0%) Shares 360,577 (-20.1%) Est. Cost $224.18 Unrealized +62.1%

ABT ABBOTT LABS 3.1%

Value ($000) $164,996 (-16.7%) Shares 1,316,915 (-10.9%) Est. Cost $78.52 Unrealized +62.1%

IONS IONIS PHARMACEUTICALS INC 7.2%

Value ($000) $379,902 (-7.0%) Shares 4,802,199 (-23.1%) Est. Cost $61.40 Unrealized +22.6%

ISRG INTUITIVE SURGICAL INC 3.5%

Value ($000) $182,384 (+17.0%) Shares 322,028 (-7.6%) Est. Cost $268.75 Unrealized +98.1%

ARGX ARGENX SE 7.4%

Value ($000) $388,396 (-3.6%) Shares 461,854 (-15.5%) Est. Cost $157.09 Unrealized —

TMO THERMO FISHER SCIENTIFIC INC 0.7%

Value ($000) $37,709 (-26.8%) Shares 65,077 (-38.7%) Est. Cost $470.67 Unrealized +20.1%

EHC ENCOMPASS HEALTH CORP 0.0%

Value ($000) $2,026 (-87.0%) Shares 19,089 (-84.5%) Est. Cost $94.80 Unrealized +22.0%

BSX BOSTON SCIENTIFIC CORP 2.8%

Value ($000) $148,708 (-8.2%) Shares 1,559,606 (-6.0%) Est. Cost $39.68 Unrealized +147.1%

PODD INSULET CORP 1.0%

Value ($000) $53,067 (-18.9%) Shares 186,699 (-11.9%) Est. Cost $199.47 Unrealized +56.7%

EXAS EXACT SCIENCES CORP 0.0%

Value ($000) $1,631 (-88.2%) Shares 16,062 (-93.6%) Est. Cost $67.99 Unrealized +18.1%

VEEV VEEVA SYS INC 0.3%

Value ($000) $17,976 (-38.1%) Shares 80,529 (-17.4%) Est. Cost $197.26 Unrealized +34.5%

ONC BEONE MEDICINES LTD 0.0%

Value ($000) $574 (-95.0%) Shares 1,890 (-94.4%) Est. Cost $211.54 Unrealized —

ELV ELEVANCE HEALTH INC FORMERLY 0.5%

Value ($000) $24,414 (-28.0%) Shares 69,645 (-33.7%) Est. Cost $357.03 Unrealized -5.7%

MOH MOLINA HEALTHCARE INC 0.2%

Value ($000) $8,091 (-53.5%) Shares 46,626 (-48.8%) Est. Cost $236.59 Unrealized -30.5%

ABBV ABBVIE INC 0.6%

Value ($000) $30,814 (-22.1%) Shares 134,859 (-21.1%) Est. Cost $180.55 Unrealized +26.0%

MCK MCKESSON CORP 0.4%

Value ($000) $20,588 (-29.8%) Shares 25,098 (-33.9%) Est. Cost $592.29 Unrealized +37.7%

HCA HCA HEALTHCARE INC 0.4%

Value ($000) $20,498 (-26.7%) Shares 43,906 (-33.1%) Est. Cost $223.94 Unrealized +107.1%

EWTX EDGEWISE THERAPEUTICS INC 0.7%

Value ($000) $37,930 (-15.8%) Shares 1,528,518 (-44.9%) Est. Cost $15.98 Unrealized +25.6%

RMD RESMED INC 0.7%

Value ($000) $38,832 (-13.9%) Shares 161,214 (-2.2%) Est. Cost $188.96 Unrealized +35.2%

PRVA PRIVIA HEALTH GROUP INC 0.2%

Value ($000) $10,626 (-35.9%) Shares 448,163 (-32.7%) Est. Cost $31.03 Unrealized -21.6%

NBIX NEUROCRINE BIOSCIENCES INC 4.6%

Value ($000) $241,580 (-2.4%) Shares 1,703,304 (-3.4%) Est. Cost $83.66 Unrealized +73.2%

LLY ELI LILLY & CO 0.7%

Value ($000) $36,542 (+18.2%) Shares 34,003 (-16.1%) Est. Cost $420.39 Unrealized +127.3%

DGX QUEST DIAGNOSTICS INC 0.0%

Value ($000) $1,263 (-79.9%) Shares 7,280 (-77.9%) Est. Cost $172.09 Unrealized +5.8%

CI THE CIGNA GROUP 0.6%

Value ($000) $30,279 (-14.2%) Shares 110,013 (-10.2%) Est. Cost $273.46 Unrealized +2.1%

PEN PENUMBRA INC 0.8%

Value ($000) $42,096 (+13.1%) Shares 135,395 (-7.8%) Est. Cost $200.28 Unrealized +37.9%

WVE WAVE LIFE SCIENCES LTD 0.5%

Value ($000) $25,339 (-15.5%) Shares 1,490,518 (-63.6%) Est. Cost $16.12 Unrealized -37.0%

PHR PHREESIA INC 0.1%

Value ($000) $3,100 (-57.9%) Shares 183,213 (-41.5%) Est. Cost $34.11 Unrealized -39.5%

GMED GLOBUS MED INC 0.4%

Value ($000) $22,935 (+22.5%) Shares 262,683 (-19.6%) Est. Cost $54.84 Unrealized +38.4%

BDX BECTON DICKINSON & CO 1.0%

Value ($000) $51,557 (-7.2%) Shares 265,662 (-10.5%) Est. Cost $218.55 Unrealized -13.3%

ALGN ALIGN TECHNOLOGY INC 0.4%

Value ($000) $22,091 (+21.9%) Shares 141,474 (-2.2%) Est. Cost $307.47 Unrealized -53.4%

STE STERIS PLC 0.5%

Value ($000) $25,784 (-11.8%) Shares 101,705 (-13.9%) Est. Cost $221.24 Unrealized +13.5%

LH LABCORP HOLDINGS INC 0.0%

Value ($000) $1,422 (-67.1%) Shares 5,669 (-62.4%) Est. Cost $240.40 Unrealized +10.3%

OMDA OMADA HEALTH INC 0.1%

Value ($000) $2,807 (-49.6%) Shares 177,897 (-29.3%) Est. Cost $17.31 Unrealized +17.2%

ZBH ZIMMER BIOMET HOLDINGS INC 0.4%

Value ($000) $21,462 (-11.1%) Shares 238,680 (-2.7%) Est. Cost $118.00 Unrealized -19.8%

SIBN SI-BONE INC 0.0%

Value ($000) $1,781 (-59.5%) Shares 90,331 (-69.8%) Est. Cost $17.88 Unrealized -2.8%

REGN REGENERON PHARMACEUTICALS 0.2%

Value ($000) $10,751 (+27.0%) Shares 13,928 (-7.5%) Est. Cost $857.89 Unrealized -20.9%

BTSG BRIGHTSPRING HEALTH SVCS INC 0.1%

Value ($000) $3,449 (-38.8%) Shares 92,095 (-51.7%) Est. Cost $17.95 Unrealized +86.9%

NTRA NATERA INC 0.2%

Value ($000) $12,837 (-13.1%) Shares 56,036 (-39.0%) Est. Cost $74.76 Unrealized +179.0%

TEVA TEVA PHARMACEUTICAL INDS LTD 0.2%

Value ($000) $10,233 (+19.5%) Shares 327,863 (-22.7%) Est. Cost $16.59 Unrealized —

BMRN BIOMARIN PHARMACEUTICAL INC 0.1%

Value ($000) $3,863 (-29.4%) Shares 65,008 (-35.7%) Est. Cost $83.12 Unrealized -34.5%

LEGN LEGEND BIOTECH CORP 0.0%

Value ($000) $1,391 (-49.8%) Shares 63,971 (-24.7%) Est. Cost $45.72 Unrealized —

COR CENCORA INC 0.0%

Value ($000) $176 (-88.4%) Shares 521 (-89.3%) Est. Cost $190.39 Unrealized +78.9%

AXSM AXSOME THERAPEUTICS INC 0.1%

Value ($000) $5,041 (-20.7%) Shares 27,600 (-47.3%) Est. Cost $56.28 Unrealized +148.1%

GPCR STRUCTURE THERAPEUTICS INC 0.2%

Value ($000) $10,096 (+14.2%) Shares 145,167 (-54.0%) Est. Cost $34.28 Unrealized —

TMDX TRANSMEDICS GROUP INC 0.2%

Value ($000) $11,908 (-9.3%) Shares 97,885 (-16.3%) Est. Cost $30.57 Unrealized +310.5%

CNC CENTENE CORP DEL 0.2%

Value ($000) $11,262 (+11.9%) Shares 273,674 (-2.9%) Est. Cost $46.52 Unrealized -19.5%

HUM HUMANA INC 0.4%

Value ($000) $18,718 (-5.7%) Shares 73,081 (-4.2%) Est. Cost $307.13 Unrealized -14.9%

CAH CARDINAL HEALTH INC 0.0%

Value ($000) $1,576 (-38.3%) Shares 7,669 (-52.9%) Est. Cost $98.91 Unrealized +89.8%

ILMN ILLUMINA INC 0.1%

Value ($000) $3,009 (+33.1%) Shares 22,940 (-3.6%) Est. Cost $276.89 Unrealized -57.6%

IQV IQVIA HLDGS INC 0.2%

Value ($000) $9,302 (-7.4%) Shares 41,267 (-22.0%) Est. Cost $206.31 Unrealized +5.5%

INSM INSMED INC 0.0%

Value ($000) $2,422 (-17.0%) Shares 13,915 (-31.3%) Est. Cost $28.84 Unrealized +532.8%

VKTX VIKING THERAPEUTICS INC 0.0%

Value ($000) $2,416 (+20.8%) Shares 68,665 (-9.7%) Est. Cost $29.83 Unrealized +18.8%

NEO NEOGENOMICS INC 0.1%

Value ($000) $3,273 (+14.5%) Shares 278,286 (-24.8%) Est. Cost $14.92 Unrealized -27.7%

MLYS MINERALYS THERAPEUTICS INC 0.0%

Value ($000) $719 (-28.7%) Shares 19,826 (-25.5%) Est. Cost $16.27 Unrealized +146.5%

ASND ASCENDIS PHARMA A/S 0.1%

Value ($000) $5,188 (+4.8%) Shares 24,330 (-2.3%) Est. Cost $170.28 Unrealized —

CDNA CAREDX INC 0.2%

Value ($000) $8,121 (-2.5%) Shares 431,070 (-24.8%) Est. Cost $33.63 Unrealized -50.2%

GRMN GARMIN LTD 0.0%

Value ($000) $350 (-30.0%) Shares 1,726 (-15.0%) Est. Cost $186.62 Unrealized +16.1%

SMMT SUMMIT THERAPEUTICS INC 0.0%

Value ($000) $249 (-36.4%) Shares 14,262 (-24.9%) Est. Cost $17.36 Unrealized +8.4%

SNY SANOFI SA 0.0%

Value ($000) $284 (-32.2%) Shares 5,851 (-34.0%) Est. Cost $47.20 Unrealized —

TEM TEMPUS AI INC 0.0%

Value ($000) $282 (-30.3%) Shares 4,776 (-4.7%) Est. Cost $68.18 Unrealized +14.7%

CAI CARIS LIFE SCIENCES INC 0.0%

Value ($000) $173 (-40.4%) Shares 6,418 (-33.2%) Est. Cost $26.95 Unrealized +4.5%

RYTM RHYTHM PHARMACEUTICALS INC 0.0%

Value ($000) $803 (-12.1%) Shares 7,504 (-17.1%) Est. Cost $42.97 Unrealized +146.9%

PLNT PLANET FITNESS INC 0.0%

Value ($000) $344 (-22.9%) Shares 3,173 (-26.2%) Est. Cost $102.44 Unrealized +0.5%

GDX VANECK ETF TRUST 0.0%

Value ($000) $1,329 (-5.9%) Shares 15,500 (-16.2%) Est. Cost $33.91 Unrealized —

ORCL ORACLE CORP 0.0%

Value ($000) $40 (-66.3%) Shares 203 (-51.3%) Est. Cost $114.45 Unrealized +108.0%

PTGX PROTAGONIST THERAPEUTICS INC 0.0%

Value ($000) $1,445 (+5.7%) Shares 16,543 (-19.6%) Est. Cost $33.92 Unrealized +141.3%

AZN ASTRAZENECA PLC 0.1%

Value ($000) $2,798 (+2.3%) Shares 30,431 (-14.6%) Est. Cost $70.83 Unrealized —

A AGILENT TECHNOLOGIES INC 0.0%

Value ($000) $48 (-54.0%) Shares 350 (-56.6%) Est. Cost $127.78 Unrealized +12.5%

GEHC GE HEALTHCARE TECHNOLOGIES I 0.7%

Value ($000) $34,819 (+0.1%) Shares 424,514 (-8.3%) Est. Cost $70.33 Unrealized +10.8%

QCOM QUALCOMM INC 0.0%

Value ($000) $36 (-51.9%) Shares 209 (-53.2%) Est. Cost $133.12 Unrealized +28.3%

BIIB BIOGEN INC 0.0%

Value ($000) $627 (+6.3%) Shares 3,565 (-15.4%) Est. Cost $146.12 Unrealized +11.8%

ZTS ZOETIS INC 0.0%

Value ($000) $92 (-28.1%) Shares 729 (-16.4%) Est. Cost $169.47 Unrealized -23.1%

MRNA MODERNA INC 0.0%

Value ($000) $227 (-5.8%) Shares 7,711 (-17.4%) Est. Cost $37.72 Unrealized -28.0%

KMTS KESTRA MED TECHNOLOGIES LTD 0.1%

Value ($000) $3,070 (+0.4%) Shares 115,755 (-10.1%) Est. Cost $22.98 Unrealized +12.1%

RXRX RECURSION PHARMACEUTICALS IN 0.0%

Value ($000) $20 (-25.2%) Shares 4,921 (-10.8%) Est. Cost $10.66 Unrealized -53.5%

MTD METTLER TOLEDO INTERNATIONAL 0.0%

Value ($000) $53 (+2.8%) Shares 38 (-9.5%) Est. Cost $1170.94 Unrealized +19.3%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
RVMD	REVOLUTION MEDICINES INC	5,005,719 (-10.2%)	$398,706 (+53.2%)	7.6%	$32.29	+103.1%	COM	76155X100
INCY	INCYTE CORP	4,773 (-99.7%)	$471 (-99.6%)	0.0%	$80.18	+20.7%	COM	45337C102
BEAM	BEAM THERAPEUTICS INC	111,510 (-96.1%)	$3,091 (-95.6%)	0.1%	$33.72	-24.3%	COM	07373V105
SYK	STRYKER CORPORATION	360,577 (-20.1%)	$126,732 (-24.0%)	2.4%	$224.18	+62.1%	COM	863667101
ABT	ABBOTT LABS	1,316,915 (-10.9%)	$164,996 (-16.7%)	3.1%	$78.52	+62.1%	COM	002824100
IONS	IONIS PHARMACEUTICALS INC	4,802,199 (-23.1%)	$379,902 (-7.0%)	7.2%	$61.40	+22.6%	COM	462222100
ISRG	INTUITIVE SURGICAL INC	322,028 (-7.6%)	$182,384 (+17.0%)	3.5%	$268.75	+98.1%	COM NEW	46120E602
ARGX	ARGENX SE	461,854 (-15.5%)	$388,396 (-3.6%)	7.4%	$157.09	—	SPONSORED ADR	04016X101
TMO	THERMO FISHER SCIENTIFIC INC	65,077 (-38.7%)	$37,709 (-26.8%)	0.7%	$470.67	+20.1%	COM	883556102
EHC	ENCOMPASS HEALTH CORP	19,089 (-84.5%)	$2,026 (-87.0%)	0.0%	$94.80	+22.0%	COM	29261A100
BSX	BOSTON SCIENTIFIC CORP	1,559,606 (-6.0%)	$148,708 (-8.2%)	2.8%	$39.68	+147.1%	COM	101137107
PODD	INSULET CORP	186,699 (-11.9%)	$53,067 (-18.9%)	1.0%	$199.47	+56.7%	COM	45784P101
EXAS	EXACT SCIENCES CORP	16,062 (-93.6%)	$1,631 (-88.2%)	0.0%	$67.99	+18.1%	COM	30063P105
VEEV	VEEVA SYS INC	80,529 (-17.4%)	$17,976 (-38.1%)	0.3%	$197.26	+34.5%	CL A COM	922475108
ONC	BEONE MEDICINES LTD	1,890 (-94.4%)	$574 (-95.0%)	0.0%	$211.54	—	SPONSORED ADS	07725L102
ELV	ELEVANCE HEALTH INC FORMERLY	69,645 (-33.7%)	$24,414 (-28.0%)	0.5%	$357.03	-5.7%	COM	036752103
MOH	MOLINA HEALTHCARE INC	46,626 (-48.8%)	$8,091 (-53.5%)	0.2%	$236.59	-30.5%	COM	60855R100
ABBV	ABBVIE INC	134,859 (-21.1%)	$30,814 (-22.1%)	0.6%	$180.55	+26.0%	COM	00287Y109
MCK	MCKESSON CORP	25,098 (-33.9%)	$20,588 (-29.8%)	0.4%	$592.29	+37.7%	COM	58155Q103
HCA	HCA HEALTHCARE INC	43,906 (-33.1%)	$20,498 (-26.7%)	0.4%	$223.94	+107.1%	COM	40412C101
EWTX	EDGEWISE THERAPEUTICS INC	1,528,518 (-44.9%)	$37,930 (-15.8%)	0.7%	$15.98	+25.6%	COM	28036F105
RMD	RESMED INC	161,214 (-2.2%)	$38,832 (-13.9%)	0.7%	$188.96	+35.2%	COM	761152107
PRVA	PRIVIA HEALTH GROUP INC	448,163 (-32.7%)	$10,626 (-35.9%)	0.2%	$31.03	-21.6%	COM	74276R102
NBIX	NEUROCRINE BIOSCIENCES INC	1,703,304 (-3.4%)	$241,580 (-2.4%)	4.6%	$83.66	+73.2%	COM	64125C109
LLY	ELI LILLY & CO	34,003 (-16.1%)	$36,542 (+18.2%)	0.7%	$420.39	+127.3%	COM	532457108
DGX	QUEST DIAGNOSTICS INC	7,280 (-77.9%)	$1,263 (-79.9%)	0.0%	$172.09	+5.8%	COM	74834L100
CI	THE CIGNA GROUP	110,013 (-10.2%)	$30,279 (-14.2%)	0.6%	$273.46	+2.1%	COM	125523100
PEN	PENUMBRA INC	135,395 (-7.8%)	$42,096 (+13.1%)	0.8%	$200.28	+37.9%	COM	70975L107
WVE	WAVE LIFE SCIENCES LTD	1,490,518 (-63.6%)	$25,339 (-15.5%)	0.5%	$16.12	-37.0%	SHS	Y95308105
PHR	PHREESIA INC	183,213 (-41.5%)	$3,100 (-57.9%)	0.1%	$34.11	-39.5%	COM	71944F106
GMED	GLOBUS MED INC	262,683 (-19.6%)	$22,935 (+22.5%)	0.4%	$54.84	+38.4%	CL A	379577208
BDX	BECTON DICKINSON & CO	265,662 (-10.5%)	$51,557 (-7.2%)	1.0%	$218.55	-13.3%	COM	075887109
ALGN	ALIGN TECHNOLOGY INC	141,474 (-2.2%)	$22,091 (+21.9%)	0.4%	$307.47	-53.4%	COM	016255101
STE	STERIS PLC	101,705 (-13.9%)	$25,784 (-11.8%)	0.5%	$221.24	+13.5%	SHS USD	G8473T100
LH	LABCORP HOLDINGS INC	5,669 (-62.4%)	$1,422 (-67.1%)	0.0%	$240.40	+10.3%	COM SHS	504922105
OMDA	OMADA HEALTH INC	177,897 (-29.3%)	$2,807 (-49.6%)	0.1%	$17.31	+17.2%	COM	68170A108
ZBH	ZIMMER BIOMET HOLDINGS INC	238,680 (-2.7%)	$21,462 (-11.1%)	0.4%	$118.00	-19.8%	COM	98956P102
SIBN	SI-BONE INC	90,331 (-69.8%)	$1,781 (-59.5%)	0.0%	$17.88	-2.8%	COM	825704109
REGN	REGENERON PHARMACEUTICALS	13,928 (-7.5%)	$10,751 (+27.0%)	0.2%	$857.89	-20.9%	COM	75886F107
BTSG	BRIGHTSPRING HEALTH SVCS INC	92,095 (-51.7%)	$3,449 (-38.8%)	0.1%	$17.95	+86.9%	COM	10950A106
NTRA	NATERA INC	56,036 (-39.0%)	$12,837 (-13.1%)	0.2%	$74.76	+179.0%	COM	632307104
TEVA	TEVA PHARMACEUTICAL INDS LTD	327,863 (-22.7%)	$10,233 (+19.5%)	0.2%	$16.59	—	SPONSORED ADS	881624209
BMRN	BIOMARIN PHARMACEUTICAL INC	65,008 (-35.7%)	$3,863 (-29.4%)	0.1%	$83.12	-34.5%	COM	09061G101
LEGN	LEGEND BIOTECH CORP	63,971 (-24.7%)	$1,391 (-49.8%)	0.0%	$45.72	—	SPONSORED ADS	52490G102
COR	CENCORA INC	521 (-89.3%)	$176 (-88.4%)	0.0%	$190.39	+78.9%	COM	03073E105
AXSM	AXSOME THERAPEUTICS INC	27,600 (-47.3%)	$5,041 (-20.7%)	0.1%	$56.28	+148.1%	COM	05464T104
GPCR	STRUCTURE THERAPEUTICS INC	145,167 (-54.0%)	$10,096 (+14.2%)	0.2%	$34.28	—	SPONSORED ADS	86366E106
TMDX	TRANSMEDICS GROUP INC	97,885 (-16.3%)	$11,908 (-9.3%)	0.2%	$30.57	+310.5%	COM	89377M109
CNC	CENTENE CORP DEL	273,674 (-2.9%)	$11,262 (+11.9%)	0.2%	$46.52	-19.5%	COM	15135B101
HUM	HUMANA INC	73,081 (-4.2%)	$18,718 (-5.7%)	0.4%	$307.13	-14.9%	COM	444859102
CAH	CARDINAL HEALTH INC	7,669 (-52.9%)	$1,576 (-38.3%)	0.0%	$98.91	+89.8%	COM	14149Y108
ILMN	ILLUMINA INC	22,940 (-3.6%)	$3,009 (+33.1%)	0.1%	$276.89	-57.6%	COM	452327109
IQV	IQVIA HLDGS INC	41,267 (-22.0%)	$9,302 (-7.4%)	0.2%	$206.31	+5.5%	COM	46266C105
INSM	INSMED INC	13,915 (-31.3%)	$2,422 (-17.0%)	0.0%	$28.84	+532.8%	COM PAR $.01	457669307
VKTX	VIKING THERAPEUTICS INC	68,665 (-9.7%)	$2,416 (+20.8%)	0.0%	$29.83	+18.8%	COM	92686J106
NEO	NEOGENOMICS INC	278,286 (-24.8%)	$3,273 (+14.5%)	0.1%	$14.92	-27.7%	COM NEW	64049M209
MLYS	MINERALYS THERAPEUTICS INC	19,826 (-25.5%)	$719 (-28.7%)	0.0%	$16.27	+146.5%	COM	603170101
ASND	ASCENDIS PHARMA A/S	24,330 (-2.3%)	$5,188 (+4.8%)	0.1%	$170.28	—	SPONSORED ADR	04351P101
CDNA	CAREDX INC	431,070 (-24.8%)	$8,121 (-2.5%)	0.2%	$33.63	-50.2%	COM	14167L103
GRMN	GARMIN LTD	1,726 (-15.0%)	$350 (-30.0%)	0.0%	$186.62	+16.1%	SHS	H2906T109
SMMT	SUMMIT THERAPEUTICS INC	14,262 (-24.9%)	$249 (-36.4%)	0.0%	$17.36	+8.4%	COM	86627T108
SNY	SANOFI SA	5,851 (-34.0%)	$284 (-32.2%)	0.0%	$47.20	—	SPONSORED ADR	80105N105
TEM	TEMPUS AI INC	4,776 (-4.7%)	$282 (-30.3%)	0.0%	$68.18	+14.7%	CL A	88023B103
CAI	CARIS LIFE SCIENCES INC	6,418 (-33.2%)	$173 (-40.4%)	0.0%	$26.95	+4.5%	COM	142152107
RYTM	RHYTHM PHARMACEUTICALS INC	7,504 (-17.1%)	$803 (-12.1%)	0.0%	$42.97	+146.9%	COM	76243J105
PLNT	PLANET FITNESS INC	3,173 (-26.2%)	$344 (-22.9%)	0.0%	$102.44	+0.5%	CL A	72703H101
GDX	VANECK ETF TRUST	15,500 (-16.2%)	$1,329 (-5.9%)	0.0%	$33.91	—	GOLD MINERS ETF	92189F106
ORCL	ORACLE CORP	203 (-51.3%)	$40 (-66.3%)	0.0%	$114.45	+108.0%	COM	68389X105
PTGX	PROTAGONIST THERAPEUTICS INC	16,543 (-19.6%)	$1,445 (+5.7%)	0.0%	$33.92	+141.3%	COM	74366E102
AZN	ASTRAZENECA PLC	30,431 (-14.6%)	$2,798 (+2.3%)	0.1%	$70.83	—	SPONSORED ADR	046353108
A	AGILENT TECHNOLOGIES INC	350 (-56.6%)	$48 (-54.0%)	0.0%	$127.78	+12.5%	COM	00846U101
GEHC	GE HEALTHCARE TECHNOLOGIES I	424,514 (-8.3%)	$34,819 (+0.1%)	0.7%	$70.33	+10.8%	COMMON STOCK	36266G107
QCOM	QUALCOMM INC	209 (-53.2%)	$36 (-51.9%)	0.0%	$133.12	+28.3%	COM	747525103
BIIB	BIOGEN INC	3,565 (-15.4%)	$627 (+6.3%)	0.0%	$146.12	+11.8%	COM	09062X103
ZTS	ZOETIS INC	729 (-16.4%)	$92 (-28.1%)	0.0%	$169.47	-23.1%	CL A	98978V103
MRNA	MODERNA INC	7,711 (-17.4%)	$227 (-5.8%)	0.0%	$37.72	-28.0%	COM	60770K107
KMTS	KESTRA MED TECHNOLOGIES LTD	115,755 (-10.1%)	$3,070 (+0.4%)	0.1%	$22.98	+12.1%	SHS	G52441105
RXRX	RECURSION PHARMACEUTICALS IN	4,921 (-10.8%)	$20 (-25.2%)	0.0%	$10.66	-53.5%	CL A	75629V104
MTD	METTLER TOLEDO INTERNATIONAL	38 (-9.5%)	$53 (+2.8%)	0.0%	$1170.94	+19.3%	COM	592688105

Unchanged Positions (15)

RLAY RELAY THERAPEUTICS INC 1.3%

Value ($000) $70,602 Shares 8,345,364 Est. Cost $21.23 Unrealized -66.4%

ALNY ALNYLAM PHARMACEUTICALS INC 3.4%

Value ($000) $177,313 Shares 445,903 Est. Cost $86.59 Unrealized +411.1%

ANNX ANNEXON INC 0.5%

Value ($000) $25,890 Shares 5,157,290 Est. Cost $5.18 Unrealized -26.2%

IMCR IMMUNOCORE HLDGS PLC 1.8%

Value ($000) $97,077 Shares 2,796,803 Est. Cost $44.88 Unrealized —

COO COOPER COS INC 0.5%

Value ($000) $23,929 Shares 291,959 Est. Cost $96.75 Unrealized -22.6%

MASI MASIMO CORP 0.2%

Value ($000) $12,653 Shares 97,285 Est. Cost $165.13 Unrealized -13.3%

MDT MEDTRONIC PLC 1.4%

Value ($000) $73,639 Shares 766,592 Est. Cost $78.48 Unrealized +23.8%

THC TENET HEALTHCARE CORP 0.2%

Value ($000) $7,996 Shares 40,239 Est. Cost $177.42 Unrealized +13.9%

QURE UNIQURE NV 0.0%

Value ($000) $114 Shares 4,763 Est. Cost $8.63 Unrealized +347.0%

SPY SPDR S&P 500 ETF TR 0.0%

Value ($000) $2,114 Shares 3,100 Est. Cost $586.08 Unrealized —

AMRX AMNEAL PHARMACEUTICALS INC 0.0%

Value ($000) $100 Shares 7,913 Est. Cost $8.98 Unrealized +27.5%

EXEL EXELIXIS INC 0.0%

Value ($000) $323 Shares 7,361 Est. Cost $35.63 Unrealized +16.1%

ALKS ALKERMES PLC 0.0%

Value ($000) $185 Shares 6,594 Est. Cost $28.20 Unrealized +6.2%

IWM ISHARES TR 0.0%

Value ($000) $566 Shares 2,300 Est. Cost $199.49 Unrealized —

GMAB GENMAB A/S 0.0%

Value ($000) $93 Shares 3,009 Est. Cost $30.67 Unrealized —

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
RLAY	RELAY THERAPEUTICS INC	8,345,364	$70,602	1.3%	$21.23	-66.4%	COM	75943R102
ALNY	ALNYLAM PHARMACEUTICALS INC	445,903	$177,313	3.4%	$86.59	+411.1%	COM	02043Q107
ANNX	ANNEXON INC	5,157,290	$25,890	0.5%	$5.18	-26.2%	COM	03589W102
IMCR	IMMUNOCORE HLDGS PLC	2,796,803	$97,077	1.8%	$44.88	—	ADS	45258D105
COO	COOPER COS INC	291,959	$23,929	0.5%	$96.75	-22.6%	COM	216648501
MASI	MASIMO CORP	97,285	$12,653	0.2%	$165.13	-13.3%	COM	574795100
MDT	MEDTRONIC PLC	766,592	$73,639	1.4%	$78.48	+23.8%	SHS	G5960L103
THC	TENET HEALTHCARE CORP	40,239	$7,996	0.2%	$177.42	+13.9%	COM NEW	88033G407
QURE	UNIQURE NV	4,763	$114	0.0%	$8.63	+347.0%	SHS	N90064101
SPY	SPDR S&P 500 ETF TR	3,100	$2,114	0.0%	$586.08	—	TR UNIT	78462F103
AMRX	AMNEAL PHARMACEUTICALS INC	7,913	$100	0.0%	$8.98	+27.5%	COM STK CL A	03168L105
EXEL	EXELIXIS INC	7,361	$323	0.0%	$35.63	+16.1%	COM	30161Q104
ALKS	ALKERMES PLC	6,594	$185	0.0%	$28.20	+6.2%	SHS	G01767105
IWM	ISHARES TR	2,300	$566	0.0%	$199.49	—	RUSSELL 2000 ETF	464287655
GMAB	GENMAB A/S	3,009	$93	0.0%	$30.67	—	SPONSORED ADS	372303206