ORBIMED ADVISORS LLC Diversified Active

Location: New York, NY

CIK: 0001055951 · Show all filings

Period: Q4 2024 (← Previous) (Next →)

Filing Date: Feb 14, 2025

Total Value: $4.861B (100.0% shares, 0.0% debt)

Holdings (118)

EWTX EDGEWISE THERAPEUTICS INC 8.3%
Value $401M Shares 15,021,721 Est. Cost Unrealized
SVA SINOVAC BIOTECH LTD 6.9%
Value $334M Shares 2,718,735 Est. Cost Unrealized
BSX BOSTON SCIENTIFIC CORP 5.8%
Value $282M Shares 3,160,300 Est. Cost Unrealized
LLY ELI LILLY & CO 5.4%
Value $261M Shares 337,600 Est. Cost Unrealized
ISRG INTUITIVE SURGICAL INC 4.3%
Value $210M Shares 401,700 Est. Cost Unrealized
ELVN ENLIVEN THERAPEUTICS INC 3.7%
Value $179M Shares 7,959,538 Est. Cost Unrealized
NBIX NEUROCRINE BIOSCIENCES INC 2.6%
Value $128M Shares 938,120 Est. Cost Unrealized
SYK STRYKER CORPORATION 2.6%
Value $124M Shares 344,400 Est. Cost Unrealized
SRPT SAREPTA THERAPEUTICS INC 2.4%
Value $117M Shares 963,400 Est. Cost Unrealized
ARGX ARGENX SE 2.4%
Value $117M Shares 189,700 Est. Cost Unrealized
IRON DISC MEDICINE INC 2.3%
Value $113M Shares 1,785,571 Est. Cost Unrealized
THC TENET HEALTHCARE CORP 2.1%
Value $99.97M Shares 792,000 Est. Cost Unrealized
IONS IONIS PHARMACEUTICALS INC 2.0%
Value $98.49M Shares 2,817,347 Est. Cost Unrealized
ALNY ALNYLAM PHARMACEUTICALS INC 2.0%
Value $97.79M Shares 415,600 Est. Cost Unrealized
UPB UPSTREAM BIO INC 1.9%
Value $93.6M Shares 5,693,589 Est. Cost Unrealized
SPRY ARS PHARMACEUTICALS INC 1.8%
Value $87.44M Shares 8,288,510 Est. Cost Unrealized
EW EDWARDS LIFESCIENCES CORP 1.7%
Value $84.79M Shares 1,145,302 Est. Cost Unrealized
MRK MERCK & CO INC 1.7%
Value $82.56M Shares 829,900 Est. Cost Unrealized
AVBP ARRIVENT BIOPHARMA INC 1.7%
Value $80.65M Shares 3,027,328 Est. Cost Unrealized
BIIB BIOGEN INC 1.6%
Value $77.85M Shares 509,100 Est. Cost Unrealized
ITGR INTEGER HLDGS CORP 1.6%
Value $76.2M Shares 575,000 Est. Cost Unrealized
CYTK CYTOKINETICS INC 1.5%
Value $74.51M Shares 1,584,005 Est. Cost Unrealized
MBX MBX BIOSCIENCES INC 1.4%
Value $70.26M Shares 3,812,215 Est. Cost Unrealized
UNH UNITEDHEALTH GROUP INC 1.4%
Value $66.22M Shares 130,900 Est. Cost Unrealized
NTRA NATERA INC 1.3%
Value $65.38M Shares 413,000 Est. Cost Unrealized
VRTX VERTEX PHARMACEUTICALS INC 1.3%
Value $60.81M Shares 151,000 Est. Cost Unrealized
THIRD HARMONIC BIO INC 1.2%
Value $59.47M Shares 5,779,071 Est. Cost Unrealized
CRNX CRINETICS PHARMACEUTICALS IN 1.1%
Value $51.08M Shares 999,000 Est. Cost Unrealized
UHS UNIVERSAL HLTH SVCS INC 1.0%
Value $48.32M Shares 269,300 Est. Cost Unrealized
SIBN SI-BONE INC 1.0%
Value $48.27M Shares 3,442,853 Est. Cost Unrealized
SPRINGWORKS THERAPEUTICS INC 0.9%
Value $45.34M Shares 1,255,031 Est. Cost Unrealized
TMO THERMO FISHER SCIENTIFIC INC 0.9%
Value $43.91M Shares 84,400 Est. Cost Unrealized
TERN TERNS PHARMACEUTICALS INC 0.9%
Value $41.9M Shares 7,562,971 Est. Cost Unrealized
CGON CG ONCOLOGY INC 0.8%
Value $41.04M Shares 1,431,114 Est. Cost Unrealized
JANX JANUX THERAPEUTICS INC 0.8%
Value $40.61M Shares 758,566 Est. Cost Unrealized
EXAS EXACT SCIENCES CORP 0.8%
Value $38.2M Shares 679,816 Est. Cost Unrealized
NPCE NEUROPACE INC 0.8%
Value $38.12M Shares 3,406,335 Est. Cost Unrealized
XENE XENON PHARMACEUTICALS INC 0.8%
Value $37.16M Shares 947,877 Est. Cost Unrealized
CRVS CORVUS PHARMACEUTICALS INC 0.8%
Value $37.15M Shares 6,943,654 Est. Cost Unrealized
XBI SPDR SER TR 0.7%
Value $33.5M Shares 372,000 Est. Cost Unrealized
CMPX COMPASS THERAPEUTICS INC 0.7%
Value $32.43M Shares 22,362,850 Est. Cost Unrealized
XTNT XTANT MED HLDGS INC 0.7%
Value $32.39M Shares 73,114,592 Est. Cost Unrealized
RNAM AVIDITY BIOSCIENCES INC 0.7%
Value $32.36M Shares 1,112,886 Est. Cost Unrealized
VERA VERA THERAPEUTICS INC 0.6%
Value $31.4M Shares 742,572 Est. Cost Unrealized
DYN DYNE THERAPEUTICS INC 0.6%
Value $28.91M Shares 1,227,080 Est. Cost Unrealized
CGEM CULLINAN THERAPEUTICS INC 0.5%
Value $23.66M Shares 1,942,555 Est. Cost Unrealized
VIR VIR BIOTECHNOLOGY INC 0.5%
Value $23.62M Shares 3,218,617 Est. Cost Unrealized
GILD GILEAD SCIENCES INC 0.5%
Value $22.69M Shares 245,600 Est. Cost Unrealized
RYTM RHYTHM PHARMACEUTICALS INC 0.5%
Value $22.39M Shares 400,000 Est. Cost Unrealized
IMTX IMMATICS N.V 0.5%
Value $21.95M Shares 3,087,462 Est. Cost Unrealized
FOLD AMICUS THERAPEUTICS INC 0.4%
Value $21.53M Shares 2,285,400 Est. Cost Unrealized
SCPHARMACEUTICALS INC 0.4%
Value $21.45M Shares 6,059,528 Est. Cost Unrealized
RAPT THERAPEUTICS INC 0.4%
Value $20.75M Shares 13,135,260 Est. Cost Unrealized
TYRA TYRA BIOSCIENCES INC 0.4%
Value $20.43M Shares 1,470,086 Est. Cost Unrealized
MLYS MINERALYS THERAPEUTICS INC 0.4%
Value $19.84M Shares 1,611,637 Est. Cost Unrealized
GILD GILEAD SCIENCES INC 0.4%
Value $18.47M Shares 200,000 Est. Cost Unrealized
IKENA ONCOLOGY INC 0.4%
Value $17.69M Shares 12,048,773 Est. Cost Unrealized
GPCR STRUCTURE THERAPEUTICS INC 0.4%
Value $17.68M Shares 652,028 Est. Cost Unrealized
KROS KEROS THERAPEUTICS INC 0.3%
Value $16.13M Shares 1,018,734 Est. Cost Unrealized
CCCC C4 THERAPEUTICS INC 0.3%
Value $15.76M Shares 4,377,900 Est. Cost Unrealized
MEDP MEDPACE HLDGS INC 0.3%
Value $14.92M Shares 44,900 Est. Cost Unrealized
VSTM VERASTEM INC 0.3%
Value $14.8M Shares 2,862,448 Est. Cost Unrealized
PRLD PRELUDE THERAPEUTICS INC 0.3%
Value $13.91M Shares 10,909,256 Est. Cost Unrealized
CRBP CORBUS PHARMACEUTICALS HLDGS 0.3%
Value $13.83M Shares 1,172,287 Est. Cost Unrealized
FBRX FORTE BIOSCIENCES INC 0.3%
Value $13.63M Shares 600,000 Est. Cost Unrealized
INTRA-CELLULAR THERAPIES INC 0.3%
Value $13.61M Shares 163,000 Est. Cost Unrealized
ACELYRIN INC 0.3%
Value $12.57M Shares 4,001,711 Est. Cost Unrealized
ABCL ABCELLERA BIOLOGICS INC 0.3%
Value $12.25M Shares 4,180,768 Est. Cost Unrealized
ADCT ADC THERAPEUTICS SA 0.2%
Value $11.88M Shares 5,968,451 Est. Cost Unrealized
ADICET BIO INC 0.2%
Value $11.01M Shares 11,447,140 Est. Cost Unrealized
PMVP PMV PHARMACEUTICALS INC 0.2%
Value $9.778M Shares 6,475,291 Est. Cost Unrealized
UHS UNIVERSAL HLTH SVCS INC 0.2%
Value $8.971M Shares 50,000 Est. Cost Unrealized
NMRA NEUMORA THERAPEUTICS INC. 0.2%
Value $8.533M Shares 804,996 Est. Cost Unrealized
QTTB Q32 BIO INC 0.2%
Value $7.75M Shares 2,252,987 Est. Cost Unrealized
GERN GERON CORP 0.2%
Value $7.675M Shares 2,168,000 Est. Cost Unrealized
AVTX AVALO THERAPEUTICS INC 0.1%
Value $7.185M Shares 967,000 Est. Cost Unrealized
CRDF CARDIFF ONCOLOGY INC 0.1%
Value $6.677M Shares 1,538,462 Est. Cost Unrealized
PFE PFIZER INC 0.1%
Value $6.633M Shares 250,000 Est. Cost Unrealized
SRRK SCHOLAR ROCK HLDG CORP 0.1%
Value $6.561M Shares 151,800 Est. Cost Unrealized
INSM INSMED INC 0.1%
Value $6.528M Shares 94,559 Est. Cost Unrealized
ENGN ENGENE HOLDINGS INC 0.1%
Value $6.12M Shares 920,339 Est. Cost Unrealized
IKENA ONCOLOGY INC 0.1%
Value $5.805M Shares 3,539,358 Est. Cost Unrealized
NSPR INSPIREMD INC 0.1%
Value $5.611M Shares 2,133,405 Est. Cost Unrealized
TRAW TRAWS PHARMA INC 0.1%
Value $5.377M Shares 605,531 Est. Cost Unrealized
BIOA BIOAGE LABS INC 0.1%
Value $5.338M Shares 921,959 Est. Cost Unrealized
X4 PHARMACEUTICALS INC 0.1%
Value $5.233M Shares 7,133,515 Est. Cost Unrealized
BCAX BICARA THERAPEUTICS INC 0.1%
Value $5.196M Shares 298,301 Est. Cost Unrealized
MIST MILESTONE PHARMACEUTICALS IN 0.1%
Value $4.72M Shares 2,000,000 Est. Cost Unrealized
REPARE THERAPEUTICS INC 0.1%
Value $4.352M Shares 3,322,488 Est. Cost Unrealized
PASSAGE BIO INC 0.1%
Value $4.199M Shares 7,404,869 Est. Cost Unrealized
GPCR STRUCTURE THERAPEUTICS INC 0.1%
Value $4.068M Shares 150,000 Est. Cost Unrealized
KRYS KRYSTAL BIOTECH INC 0.1%
Value $3.682M Shares 23,500 Est. Cost Unrealized
ARDT ARDENT HEALTH PARTNERS INC 0.1%
Value $3.518M Shares 206,000 Est. Cost Unrealized
SIBN SI-BONE INC 0.1%
Value $3.505M Shares 250,000 Est. Cost Unrealized
THC TENET HEALTHCARE CORP 0.1%
Value $3.156M Shares 25,000 Est. Cost Unrealized
CHEMOMAB THERAPEUTICS LTD 0.1%
Value $3.152M Shares 1,741,273 Est. Cost Unrealized
CBLL CERIBELL INC 0.1%
Value $2.912M Shares 112,500 Est. Cost Unrealized
FATE FATE THERAPEUTICS INC 0.1%
Value $2.773M Shares 1,680,580 Est. Cost Unrealized
PEPG PEPGEN INC 0.1%
Value $2.475M Shares 653,016 Est. Cost Unrealized
TIL INSTIL BIO INC 0.0%
Value $2.229M Shares 116,785 Est. Cost Unrealized
NKTX NKARTA INC 0.0%
Value $2.045M Shares 821,400 Est. Cost Unrealized
LYELL IMMUNOPHARMA INC 0.0%
Value $1.986M Shares 3,103,623 Est. Cost Unrealized
IMVT IMMUNOVANT INC 0.0%
Value $1.944M Shares 78,500 Est. Cost Unrealized
AKERO THERAPEUTICS INC 0.0%
Value $1.836M Shares 66,000 Est. Cost Unrealized
TNGX TANGO THERAPEUTICS INC 0.0%
Value $1.7M Shares 550,000 Est. Cost Unrealized
TURNSTONE BIOLOGICS CORP 0.0%
Value $1.54M Shares 3,099,265 Est. Cost Unrealized
AMLX AMYLYX PHARMACEUTICALS INC 0.0%
Value $1.315M Shares 348,000 Est. Cost Unrealized
BIOMX INC 0.0%
Value $1.305M Shares 1,787,767 Est. Cost Unrealized
KZR KEZAR LIFE SCIENCES INC 0.0%
Value $1.295M Shares 192,700 Est. Cost Unrealized
KRRO KORRO BIO INC 0.0%
Value $1.233M Shares 32,400 Est. Cost Unrealized
ANRO ALTO NEUROSCIENCE INC 0.0%
Value $1.058M Shares 250,000 Est. Cost Unrealized
NEXTCURE INC 0.0%
Value $880K Shares 1,141,200 Est. Cost Unrealized
AGIO AGIOS PHARMACEUTICALS INC 0.0%
Value $877K Shares 26,700 Est. Cost Unrealized
CCCC C4 THERAPEUTICS INC 0.0%
Value $540K Shares 150,000 Est. Cost Unrealized
ELEVATION ONCOLOGY INC 0.0%
Value $530K Shares 941,275 Est. Cost Unrealized
IVVD INVIVYD INC 0.0%
Value $509K Shares 1,149,300 Est. Cost Unrealized
LSBCF LAKESHORE BIOPHARMA CO LTD 0.0%
Value $486K Shares 140,428 Est. Cost Unrealized
XERS XERIS BIOPHARMA HOLDINGS INC 0.0%
Value $273K Shares 80,420 Est. Cost Unrealized