ORBIMED ADVISORS LLC Diversified Active

Location: New York, NY

CIK: 0001055951 · Show all filings

Period: Q2 2025 (← Previous) (Next →)

Filing Date: Aug 14, 2025

Total Value: $4.004B (100.0% shares, 0.0% debt)

Holdings (102)

SVA SINOVAC BIOTECH LTD 8.3%
Value $334M Shares 2,718,735 Est. Cost Unrealized
BSX BOSTON SCIENTIFIC CORP 7.5%
Value $302M Shares 2,813,200 Est. Cost Unrealized
LLY ELI LILLY & CO 6.6%
Value $263M Shares 337,600 Est. Cost Unrealized
EWTX EDGEWISE THERAPEUTICS INC 5.1%
Value $203M Shares 15,518,492 Est. Cost Unrealized
ELVN ENLIVEN THERAPEUTICS INC 4.0%
Value $160M Shares 7,959,538 Est. Cost Unrealized
ISRG INTUITIVE SURGICAL INC 3.9%
Value $158M Shares 291,000 Est. Cost Unrealized
SPRY ARS PHARMACEUTICALS INC 3.6%
Value $145M Shares 8,288,510 Est. Cost Unrealized
SYK STRYKER CORPORATION 3.5%
Value $142M Shares 359,200 Est. Cost Unrealized
EW EDWARDS LIFESCIENCES CORP 3.3%
Value $134M Shares 1,708,000 Est. Cost Unrealized
ARGX ARGENX SE 2.9%
Value $115M Shares 208,000 Est. Cost Unrealized
ALNY ALNYLAM PHARMACEUTICALS INC 2.8%
Value $111M Shares 341,900 Est. Cost Unrealized
UNH UNITEDHEALTH GROUP INC 2.6%
Value $105M Shares 336,300 Est. Cost Unrealized
NTRA NATERA INC 2.5%
Value $100M Shares 593,434 Est. Cost Unrealized
VRTX VERTEX PHARMACEUTICALS INC 2.3%
Value $93.62M Shares 210,287 Est. Cost Unrealized
THC TENET HEALTHCARE CORP 2.0%
Value $81.84M Shares 465,000 Est. Cost Unrealized
CAI CARIS LIFE SCIENCES INC 2.0%
Value $81.09M Shares 3,034,858 Est. Cost Unrealized
IRON DISC MEDICINE INC 1.9%
Value $74.94M Shares 1,415,020 Est. Cost Unrealized
AVBP ARRIVENT BIOPHARMA INC 1.6%
Value $65.9M Shares 3,027,328 Est. Cost Unrealized
SION SIONNA THERAPEUTICS INC 1.6%
Value $64.28M Shares 3,704,959 Est. Cost Unrealized
UPB UPSTREAM BIO INC 1.6%
Value $62.52M Shares 5,693,589 Est. Cost Unrealized
NBIX NEUROCRINE BIOSCIENCES INC 1.4%
Value $55.12M Shares 438,540 Est. Cost Unrealized
ITGR INTEGER HLDGS CORP 1.3%
Value $53.3M Shares 433,400 Est. Cost Unrealized
RNAM AVIDITY BIOSCIENCES INC 1.3%
Value $51.49M Shares 1,812,886 Est. Cost Unrealized
CGON CG ONCOLOGY INC 1.2%
Value $48.82M Shares 1,877,850 Est. Cost Unrealized
SIBN SI-BONE INC 1.2%
Value $48.54M Shares 2,578,979 Est. Cost Unrealized
MBX MBX BIOSCIENCES INC 1.1%
Value $45.67M Shares 4,002,887 Est. Cost Unrealized
AXSM AXSOME THERAPEUTICS INC 1.1%
Value $44.67M Shares 427,900 Est. Cost Unrealized
CMPX COMPASS THERAPEUTICS INC 1.0%
Value $39.57M Shares 15,219,994 Est. Cost Unrealized
CYTK CYTOKINETICS INC 0.9%
Value $35.58M Shares 1,077,000 Est. Cost Unrealized
CRNX CRINETICS PHARMACEUTICALS IN 0.8%
Value $33.05M Shares 1,149,000 Est. Cost Unrealized
EXAS EXACT SCIENCES CORP 0.8%
Value $32.27M Shares 607,316 Est. Cost Unrealized
THIRD HARMONIC BIO INC 0.8%
Value $31.38M Shares 5,779,071 Est. Cost Unrealized
ROIV ROIVANT SCIENCES LTD 0.8%
Value $31.32M Shares 2,779,427 Est. Cost Unrealized
XENE XENON PHARMACEUTICALS INC 0.7%
Value $29.67M Shares 947,877 Est. Cost Unrealized
NPCE NEUROPACE INC 0.7%
Value $29.12M Shares 2,614,184 Est. Cost Unrealized
CRVS CORVUS PHARMACEUTICALS INC 0.7%
Value $28.66M Shares 7,165,006 Est. Cost Unrealized
TERN TERNS PHARMACEUTICALS INC 0.7%
Value $28.21M Shares 7,562,971 Est. Cost Unrealized
JANX JANUX THERAPEUTICS INC 0.7%
Value $27.96M Shares 1,210,300 Est. Cost Unrealized
APLS APELLIS PHARMACEUTICALS INC 0.6%
Value $25.66M Shares 1,482,300 Est. Cost Unrealized
GPCR STRUCTURE THERAPEUTICS INC 0.6%
Value $24.87M Shares 1,199,300 Est. Cost Unrealized
SCPHARMACEUTICALS INC 0.6%
Value $23.09M Shares 6,059,528 Est. Cost Unrealized
CTMX CYTOMX THERAPEUTICS INC 0.5%
Value $19.21M Shares 8,461,500 Est. Cost Unrealized
TMO THERMO FISHER SCIENTIFIC INC 0.5%
Value $18.85M Shares 46,500 Est. Cost Unrealized
AGIO AGIOS PHARMACEUTICALS INC 0.5%
Value $18.56M Shares 557,900 Est. Cost Unrealized
TRVI TREVI THERAPEUTICS INC 0.5%
Value $18.1M Shares 3,308,400 Est. Cost Unrealized
ADCT ADC THERAPEUTICS SA 0.4%
Value $15.83M Shares 5,907,351 Est. Cost Unrealized
RYTM RHYTHM PHARMACEUTICALS INC 0.4%
Value $15.7M Shares 248,512 Est. Cost Unrealized
UNH UNITEDHEALTH GROUP INC 0.4%
Value $15.6M Shares 50,000 Est. Cost Unrealized
FBRX FORTE BIOSCIENCES INC 0.4%
Value $15.48M Shares 1,196,955 Est. Cost Unrealized
CGEM CULLINAN THERAPEUTICS INC 0.4%
Value $14.49M Shares 1,923,855 Est. Cost Unrealized
KROS KEROS THERAPEUTICS INC 0.3%
Value $13.6M Shares 1,018,734 Est. Cost Unrealized
RAPT RAPT THERAPEUTICS INC 0.3%
Value $13.14M Shares 1,641,906 Est. Cost Unrealized
IKENA ONCOLOGY INC 0.3%
Value $13.13M Shares 12,048,773 Est. Cost Unrealized
FOLD AMICUS THERAPEUTICS INC 0.3%
Value $13.1M Shares 2,285,400 Est. Cost Unrealized
VIR VIR BIOTECHNOLOGY INC 0.3%
Value $12M Shares 2,380,715 Est. Cost Unrealized
ABCL ABCELLERA BIOLOGICS INC 0.3%
Value $11.47M Shares 3,344,568 Est. Cost Unrealized
AKERO THERAPEUTICS INC 0.3%
Value $11.27M Shares 211,300 Est. Cost Unrealized
MLYS MINERALYS THERAPEUTICS INC 0.3%
Value $10.29M Shares 760,351 Est. Cost Unrealized
DYN DYNE THERAPEUTICS INC 0.2%
Value $9.819M Shares 1,031,400 Est. Cost Unrealized
CCCC C4 THERAPEUTICS INC 0.2%
Value $9.767M Shares 6,830,300 Est. Cost Unrealized
ORIC ORIC PHARMACEUTICALS INC 0.2%
Value $9.128M Shares 899,281 Est. Cost Unrealized
CPRX CATALYST PHARMACEUTICALS INC 0.2%
Value $9.047M Shares 416,900 Est. Cost Unrealized
PRLD PRELUDE THERAPEUTICS INC 0.2%
Value $8.83M Shares 10,909,256 Est. Cost Unrealized
CRBP CORBUS PHARMACEUTICALS HLDGS 0.2%
Value $8.089M Shares 1,172,287 Est. Cost Unrealized
ZLAB ZAI LAB LTD 0.2%
Value $8.078M Shares 231,000 Est. Cost Unrealized
TARS TARSUS PHARMACEUTICALS INC 0.2%
Value $8.017M Shares 197,900 Est. Cost Unrealized
WHWK WHITEHAWK THERAPEUTICS INC 0.2%
Value $7.79M Shares 4,166,000 Est. Cost Unrealized
TYRA TYRA BIOSCIENCES INC 0.2%
Value $7.7M Shares 804,603 Est. Cost Unrealized
AZN ASTRAZENECA PLC 0.2%
Value $6.988M Shares 100,000 Est. Cost Unrealized
ADICET BIO INC 0.2%
Value $6.983M Shares 11,447,140 Est. Cost Unrealized
ITEOS THERAPEUTICS INC 0.2%
Value $6.979M Shares 700,000 Est. Cost Unrealized
PMVP PMV PHARMACEUTICALS INC 0.2%
Value $6.864M Shares 6,475,291 Est. Cost Unrealized
URGN UROGEN PHARMA LTD 0.2%
Value $6.554M Shares 478,400 Est. Cost Unrealized
ASND ASCENDIS PHARMA A/S 0.1%
Value $5.937M Shares 34,400 Est. Cost Unrealized
ALMS ALUMIS INC 0.1%
Value $5.779M Shares 1,926,423 Est. Cost Unrealized
JBIO JADE BIOSCIENCES INC 0.1%
Value $5.306M Shares 531,163 Est. Cost Unrealized
NSPR INSPIREMD INC 0.1%
Value $4.843M Shares 2,133,405 Est. Cost Unrealized
AVTX AVALO THERAPEUTICS INC 0.1%
Value $4.825M Shares 967,000 Est. Cost Unrealized
IKENA ONCOLOGY INC 0.1%
Value $4.743M Shares 3,539,358 Est. Cost Unrealized
REPARE THERAPEUTICS INC 0.1%
Value $4.618M Shares 3,322,488 Est. Cost Unrealized
CGON CG ONCOLOGY INC 0.1%
Value $3.9M Shares 150,000 Est. Cost Unrealized
IMTX IMMATICS N.V 0.1%
Value $3.873M Shares 719,901 Est. Cost Unrealized
BIOA BIOAGE LABS INC 0.1%
Value $3.808M Shares 921,959 Est. Cost Unrealized
QTTB Q32 BIO INC 0.1%
Value $3.357M Shares 2,252,987 Est. Cost Unrealized
ENGN ENGENE HOLDINGS INC 0.1%
Value $2.468M Shares 677,977 Est. Cost Unrealized
PASSAGE BIO INC 0.1%
Value $2.424M Shares 6,055,300 Est. Cost Unrealized
AMLX AMYLYX PHARMACEUTICALS INC 0.1%
Value $2.008M Shares 313,200 Est. Cost Unrealized
MURAL ONCOLOGY PUB LTD CO 0.0%
Value $1.454M Shares 588,800 Est. Cost Unrealized
INSM INSMED INC 0.0%
Value $1.355M Shares 13,459 Est. Cost Unrealized
KRYS KRYSTAL BIOTECH INC 0.0%
Value $1.265M Shares 9,200 Est. Cost Unrealized
TURNSTONE BIOLOGICS CORP 0.0%
Value $1.113M Shares 3,099,265 Est. Cost Unrealized
CHEMOMAB THERAPEUTICS LTD 0.0%
Value $1.092M Shares 940,990 Est. Cost Unrealized
TRAW TRAWS PHARMA INC 0.0%
Value $896K Shares 605,531 Est. Cost Unrealized
KZR KEZAR LIFE SCIENCES INC 0.0%
Value $883K Shares 192,700 Est. Cost Unrealized
APLS APELLIS PHARMACEUTICALS INC 0.0%
Value $866K Shares 50,000 Est. Cost Unrealized
ANRO ALTO NEUROSCIENCE INC 0.0%
Value $550K Shares 250,000 Est. Cost Unrealized
DIH HLDG US INC 0.0%
Value $469K Shares 1,915,000 Est. Cost Unrealized
LYEL LYELL IMMUNOPHARMA INC 0.0%
Value $457K Shares 51,727 Est. Cost Unrealized
KRRO KORRO BIO INC 0.0%
Value $405K Shares 32,400 Est. Cost Unrealized
XERS XERIS BIOPHARMA HOLDINGS INC 0.0%
Value $376K Shares 80,420 Est. Cost Unrealized
INMB INMUNE BIO INC 0.0%
Value $116K Shares 50,000 Est. Cost Unrealized
LSBCF LAKESHORE BIOPHARMA CO LTD 0.0%
Value $55,895 Shares 54,799 Est. Cost Unrealized