Location: San Francisco, CA
CIK: 0000909661 · Show all filings
Period: Q4 2020 (← Previous) (Next →)
Filing Date: May 16, 2022
Total Value: $16.63B
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| IQV | IQVIA HLDGS INC | 4,043,506 | $724M | 4.4% | $131.93 | +27.7% | — | 46266C105 |
| GOOG | ALPHABET INC | 361,094 | $633M | 3.8% | $62.37 | +34.3% | — | 02079K107 |
| TMUS | T-MOBILE US INC | 3,949,181 | $533M | 3.2% | $95.38 | +25.1% | — | 872590104 |
| TMO | THERMO FISHER SCIENTIFIC INC | 1,114,248 | $519M | 3.1% | $307.35 | +50.5% | — | 883556102 |
| SPY | SPDR S&P 500 ETF TR | 1,365,000 | $510M | 3.1% | — | — | PUT | 78462F103 |
| V | VISA INC | 2,228,104 | $487M | 2.9% | $136.13 | +44.9% | — | 92826C839 |
| AON | AON PLC | 2,271,514 | $480M | 2.9% | $182.84 | +7.5% | — | G0403H108 |
| BSX | BOSTON SCIENTIFIC CORP | 13,238,319 | $476M | 2.9% | $37.60 | -4.1% | — | 101137107 |
| FIS | FIDELITY NATL INFORMATION SV | 3,149,118 | $445M | 2.7% | $94.85 | +34.4% | — | 31620M106 |
| ARMK | ARAMARK | 11,023,949 | $424M | 2.6% | $22.46 | 0.0% | — | 03852U106 |
| CNC | CENTENE CORP DEL | 6,850,000 | $411M | 2.5% | $60.68 | +4.7% | — | 15135B101 |
| ELV | ANTHEM INC | 1,275,000 | $409M | 2.5% | $211.68 | +35.2% | — | 036752103 |
| MSFT | MICROSOFT CORP | 1,758,168 | $391M | 2.4% | $104.30 | +97.5% | — | 594918104 |
| WAB | WABTEC | 4,997,371 | $366M | 2.2% | $72.49 | -8.4% | — | 929740108 |
| — | XILINX INC | 2,556,000 | $362M | 2.2% | $141.77 | — | — | 983919101 |
| CHTR | CHARTER COMMUNICATIONS INC N | 546,931 | $362M | 2.2% | $328.59 | +93.7% | — | 16119P108 |
| — | ALEXION PHARMACEUTICALS INC | 2,246,900 | $351M | 2.1% | $156.24 | — | — | 015351109 |
| NYT | NEW YORK TIMES CO | 6,545,329 | $339M | 2.0% | $37.41 | +12.9% | — | 650111107 |
| — | ACCELERON PHARMA INC | 2,600,000 | $333M | 2.0% | $59.58 | — | — | 00434H108 |
| RTX | RAYTHEON TECHNOLOGIES CORP | 4,542,306 | $325M | 2.0% | $58.43 | 0.0% | — | 75513E101 |
| META | FACEBOOK INC | 1,154,005 | $315M | 1.9% | $184.07 | +47.9% | — | 30303M102 |
| CRM | SALESFORCE COM INC | 1,409,045 | $314M | 1.9% | $197.95 | +21.4% | — | 79466L302 |
| — | TIFFANY & CO NEW | 2,287,000 | $301M | 1.8% | $119.92 | — | — | 886547108 |
| SHW | SHERWIN WILLIAMS CO | 389,366 | $286M | 1.7% | $143.33 | +58.2% | — | 824348106 |
| IOVA | IOVANCE BIOTHERAPEUTICS INC | 6,000,000 | $278M | 1.7% | $14.91 | +166.3% | — | 462260100 |
| FATE | FATE THERAPEUTICS INC | 3,000,000 | $273M | 1.6% | $18.49 | +235.8% | — | 31189P102 |
| AVGO | BROADCOM INC | 622,995 | $273M | 1.6% | $34.82 | 0.0% | — | 11135F101 |
| BX | BLACKSTONE GROUP INC | 3,891,886 | $252M | 1.5% | $44.03 | +10.9% | — | 09260D107 |
| EXEL | EXELIXIS INC | 11,000,000 | $221M | 1.3% | $18.28 | +14.5% | — | 30161Q104 |
| — | NEW ORIENTAL ED & TECHNOLOGY | 1,154,300 | $214M | 1.3% | $140.62 | — | — | 647581107 |
| — | SLACK TECHNOLOGIES INC | 4,912,300 | $207M | 1.2% | $42.24 | — | — | 83088V102 |
| WTW | WILLIS TOWERS WATSON PLC LTD | 962,500 | $203M | 1.2% | $192.02 | +0.1% | — | G96629103 |
| — | INPHI CORP | 1,239,800 | $199M | 1.2% | $160.47 | — | — | 45772F107 |
| BABA | ALIBABA GROUP HLDG LTD | 853,300 | $199M | 1.2% | $182.99 | — | — | 01609W102 |
| — | MIRATI THERAPEUTICS INC | 875,000 | $192M | 1.2% | $95.15 | — | — | 60468T105 |
| HLT | HILTON WORLDWIDE HLDGS INC | 1,640,437 | $183M | 1.1% | $83.41 | +17.3% | — | 43300A203 |
| — | QIAGEN NV | 3,256,771 | $172M | 1.0% | $52.85 | — | — | N72482123 |
| TRU | TRANSUNION | 1,734,082 | $172M | 1.0% | $71.12 | +25.5% | — | 89400J107 |
| ASND | ASCENDIS PHARMA A/S | 1,000,000 | $167M | 1.0% | $77.41 | — | — | 04351P101 |
| HWM | HOWMET AEROSPACE INC | 4,891,479 | $140M | 0.8% | $15.89 | +38.0% | — | 443201108 |
| — | MAXIM INTEGRATED PRODS INC | 1,542,400 | $137M | 0.8% | $71.87 | — | — | 57772K101 |
| APLS | APELLIS PHARMACEUTICALS INC | 2,275,000 | $130M | 0.8% | $33.35 | +26.8% | — | 03753U106 |
| ABBV | ABBVIE INC | 1,150,000 | $123M | 0.7% | $63.18 | +24.9% | — | 00287Y109 |
| — | AMYRIS INC | 17,500,000 | $108M | 0.6% | $4.11 | — | — | 03236M200 |
| SRPT | SAREPTA THERAPEUTICS INC | 600,000 | $102M | 0.6% | $125.37 | +18.2% | — | 803607100 |
| — | MOMO INC | 110,077,000 | $93.46M | 0.6% | $0.79 | — | — | 60879BAB3 |
| PCG | PG&E CORP | 7,292,042 | $90.86M | 0.5% | $9.16 | +22.1% | — | 69331C108 |
| — | SAGE THERAPEUTICS INC | 1,050,000 | $90.84M | 0.5% | $80.51 | — | — | 78667J108 |
| — | PLAYA HOTELS & RESORTS NV | 14,994,867 | $89.22M | 0.5% | $10.52 | — | — | N70544106 |
| — | LUFAX HOLDING LTD | 5,357,750 | $76.08M | 0.5% | $14.20 | — | — | 54975P102 |
| ENTA | ENANTA PHARMACEUTICALS INC | 1,775,000 | $74.73M | 0.4% | $60.96 | -27.8% | — | 29251M106 |
| — | BROADMARK RLTY CAP INC | 7,170,213 | $73.14M | 0.4% | $12.75 | — | — | 11135B100 |
| — | KANSAS CITY SOUTHERN | 354,400 | $72.34M | 0.4% | $180.83 | — | — | 485170302 |
| — | IQIYI INC | 81,762,000 | $71.76M | 0.4% | $0.97 | — | — | 46267XAD0 |
| EFX | EQUIFAX INC | 370,684 | $71.48M | 0.4% | $126.25 | +28.3% | — | 294429105 |
| — | KARUNA THERAPEUTICS INC | 700,000 | $71.11M | 0.4% | $76.10 | — | — | 48576A100 |
| — | FIBROGEN INC | 1,900,000 | $70.47M | 0.4% | $40.42 | — | — | 31572Q808 |
| BCAB | BIOATLA INC | 1,967,060 | $66.9M | 0.4% | $33.43 | 0.0% | — | 09077B104 |
| — | GENERATION BIO CO | 2,268,819 | $64.32M | 0.4% | $21.48 | — | — | 37148K100 |
| — | ARENA PHARMACEUTICALS INC | 750,000 | $57.62M | 0.3% | $65.17 | — | — | 040047607 |
| PACB | PACIFIC BIOSCIENCES CALIF IN | 2,100,000 | $54.47M | 0.3% | $5.26 | +223.1% | — | 69404D108 |
| — | THERAVANCE BIOPHARMA INC | 56,695,000 | $53.81M | 0.3% | $0.95 | — | — | 88339KAA0 |
| CYTK | CYTOKINETICS INC | 2,400,000 | $49.87M | 0.3% | $18.40 | -0.7% | — | 23282W605 |
| PTGX | PROTAGONIST THERAPEUTICS INC | 2,425,000 | $48.89M | 0.3% | $13.01 | +65.4% | — | 74366E102 |
| ALNY | ALNYLAM PHARMACEUTICALS INC | 350,000 | $45.49M | 0.3% | $93.53 | +42.8% | — | 02043Q107 |
| — | ZOGENIX INC | 2,250,000 | $44.98M | 0.3% | $32.99 | — | — | 98978L204 |
| — | CORELOGIC INC | 574,028 | $44.38M | 0.3% | $71.52 | — | — | 21871D103 |
| — | KARYOPHARM THERAPEUTICS INC | 35,000,000 | $43.53M | 0.3% | $1.41 | — | — | 48576UAA4 |
| AGIO | AGIOS PHARMACEUTICALS INC | 1,000,000 | $43.33M | 0.3% | $37.79 | +4.6% | — | 00847X104 |
| IONS | IONIS PHARMACEUTICALS INC | 750,000 | $42.41M | 0.3% | $49.83 | 0.0% | — | 462222100 |
| ANNX | ANNEXON INC | 1,557,261 | $38.98M | 0.2% | $23.46 | +9.7% | — | 03589W102 |
| — | RADIUS HEALTH INC | 2,107,400 | $37.64M | 0.2% | $38.73 | — | — | 750469207 |
| — | CARA THERAPEUTICS INC | 2,465,000 | $37.3M | 0.2% | $19.09 | — | — | 140755109 |
| — | INSMED INC | 32,500,000 | $36.55M | 0.2% | $1.12 | — | — | 457669AA7 |
| — | CLOVIS ONCOLOGY INC | 51,910,000 | $36.08M | 0.2% | $0.66 | — | — | 189464AC4 |
| LNTH | LANTHEUS HLDGS INC | 2,650,000 | $35.75M | 0.2% | $13.21 | -0.9% | — | 516544103 |
| — | ZYMEWORKS INC | 750,000 | $35.45M | 0.2% | $27.09 | — | — | 98985W102 |
| KRYS | KRYSTAL BIOTECH INC | 525,000 | $31.5M | 0.2% | $50.06 | -0.2% | — | 501147102 |
| NVAX | NOVAVAX INC | 275,000 | $30.66M | 0.2% | $106.29 | 0.0% | — | 670002401 |
| — | IQIYI INC | 29,689,000 | $29.89M | 0.2% | $1.12 | — | — | 46267XAB4 |
| — | PANACEA ACQUISITION CORP | 2,500,000 | $29.25M | 0.2% | $11.70 | — | — | 698102100 |
| FOLD | AMICUS THERAPEUTICS INC | 1,250,000 | $28.86M | 0.2% | $20.45 | 0.0% | — | 03152W109 |
| — | CLEVER LEAVES HOLDINGS INC | 2,478,079 | $28.73M | 0.2% | $11.59 | — | — | 186760104 |
| DMTKQ | DERMTECH INC | 861,090 | $27.93M | 0.2% | $10.94 | — | — | 24984K105 |
| BIIB | BIOGEN INC | 103,000 | $25.22M | 0.2% | $259.08 | 0.0% | — | 09062X103 |
| — | CONSTELLATION PHARMCETICLS I | 750,000 | $21.6M | 0.1% | $28.80 | — | — | 210373106 |
| BEKE | KE HLDGS INC | 343,000 | $21.11M | 0.1% | $61.31 | — | — | 482497104 |
| GRFS | GRIFOLS S A | 1,115,000 | $20.56M | 0.1% | $20.53 | — | — | 398438408 |
| — | IQIYI INC | 20,000,000 | $20M | 0.1% | $1.00 | — | — | 46267XAE8 |
| — | ZEALAND PHARMA A/S | 510,000 | $18.33M | 0.1% | $18.36 | — | — | 98920Y304 |
| ATTOF | ATENTO S A | 2,230,357 | $18.23M | 0.1% | $8.92 | +15.9% | — | L0427L204 |
| PLRX | PLIANT THERAPEUTICS INC | 764,262 | $17.36M | 0.1% | $26.54 | -5.5% | — | 729139105 |
| — | DECIPHERA PHARMACEUTICALS IN | 300,000 | $17.12M | 0.1% | $39.96 | — | — | 24344T101 |
| — | INHIBRX INC | 510,000 | $16.82M | 0.1% | $21.38 | — | — | 45720L107 |
| RC | READY CAPITAL CORP | 1,350,226 | $16.81M | 0.1% | $13.53 | — | — | 75574U101 |
| — | ADVERUM BIOTECHNOLOGIES INC | 1,500,000 | $16.26M | 0.1% | $10.30 | — | — | 00773U108 |
| BMY | BRISTOL-MYERS SQUIBB CO | 250,000 | $15.51M | 0.1% | $47.95 | +4.3% | — | 110122108 |
| — | BRISTOL-MYERS SQUIBB CO | 21,400,000 | $14.77M | 0.1% | $3.21 | — | — | 110122157 |
| — | PRAXIS PRECISION MEDICINES I | 250,000 | $13.76M | 0.1% | $55.02 | — | — | 74006W108 |
| XPO | XPO LOGISTICS INC | 110,000 | $13.11M | 0.1% | $36.23 | 0.0% | — | 983793100 |
| — | NUANCE COMMUNICATIONS INC | 7,000,000 | $13.05M | 0.1% | $1.86 | — | — | 67020YAK6 |
| NTLA | INTELLIA THERAPEUTICS INC | 225,000 | $12.24M | 0.1% | $36.31 | 0.0% | — | 45826J105 |
| — | TIGA ACQUISITION CORP | 1,080,000 | $11.43M | 0.1% | $10.58 | — | — | G88672129 |
| — | AVROBIO INC | 795,000 | $11.08M | 0.1% | $21.26 | — | — | 05455M100 |
| RCKT | ROCKET PHARMACEUTICALS INC | 200,000 | $10.97M | 0.1% | $36.45 | 0.0% | — | 77313F106 |
| QURE | UNIQURE NV | 300,000 | $10.84M | 0.1% | $52.98 | -20.4% | — | N90064101 |
| — | CASCADE ACQUISITION CORP | 990,000 | $10.35M | 0.1% | $10.45 | — | — | 147151203 |
| — | KINNATE BIOPHARMA INC | 250,000 | $9.945M | 0.1% | $39.78 | — | — | 49705R105 |
| — | ALBIREO PHARMA INC | 250,000 | $9.378M | 0.1% | $34.20 | — | — | 01345P106 |
| — | SURFACE ONCOLOGY INC | 1,000,000 | $9.24M | 0.1% | $9.24 | — | — | 86877M209 |
| — | GOSSAMER BIO INC | 10,000,000 | $9.032M | 0.1% | $0.90 | — | — | 38341PAA0 |
| — | ACACIA COMMUNICATIONS INC | 100,000 | $7.296M | 0.0% | $69.62 | — | — | 00401C108 |
| — | FIVE PRIME THERAPEUTICS INC | 400,000 | $6.804M | 0.0% | $17.01 | — | — | 33830X104 |
| COGT | COGENT BIOSCIENCES INC | 600,000 | $6.738M | 0.0% | $10.99 | 0.0% | — | 19240Q201 |
| — | IMMUNOGEN INC | 1,000,000 | $6.45M | 0.0% | $6.45 | — | — | 45253H101 |
| — | RADIUS HEALTH INC | 6,783,000 | $5.995M | 0.0% | $0.85 | — | — | 750469AA6 |
| — | MARVELL TECHNOLOGY GROUP LTD | 125,000 | $5.943M | 0.0% | — | — | CALL | G5876H105 |
| — | CURIS INC | 725,000 | $5.938M | 0.0% | $8.19 | — | — | 231269200 |
| — | APELLIS PHARMACEUTICALS INC | 3,522,000 | $5.93M | 0.0% | $1.09 | — | — | 03753UAB2 |
| STTK | SHATTUCK LABS INC | 100,000 | $5.241M | 0.0% | $32.14 | 0.0% | — | 82024L103 |
| — | IVERIC BIO INC | 754,740 | $5.215M | 0.0% | $5.10 | — | — | 46583P102 |
| TGTX | TG THERAPEUTICS INC | 100,000 | $5.202M | 0.0% | $33.79 | 0.0% | — | 88322Q108 |
| ARWR | ARROWHEAD PHARMACEUTICALS IN | 67,600 | $5.187M | 0.0% | $37.76 | +69.4% | — | 04280A100 |
| SVRA | SAVARA INC | 4,452,086 | $5.12M | 0.0% | $5.45 | -77.9% | — | 805111101 |
| — | HUMANCO ACQUISITION CORP | 400,000 | $4.408M | 0.0% | $11.02 | — | — | 44487N208 |
| MASS | 908 DEVICES INC | 75,000 | $4.271M | 0.0% | $58.41 | 0.0% | — | 65443P102 |
| FDMT | 4D MOLECULAR THERAPEUTICS IN | 100,000 | $4.145M | 0.0% | $41.28 | 0.0% | — | 35104E100 |
| KURA | KURA ONCOLOGY INC | 125,000 | $4.083M | 0.0% | $35.14 | 0.0% | — | 50127T109 |
| EQ | EQUILLIUM INC | 700,000 | $3.745M | 0.0% | $8.10 | -35.5% | — | 29446K106 |
| — | ISIS PHARMACEUTICALS INC DEL | 2,500,000 | $2.733M | 0.0% | $1.09 | — | — | 464337AJ3 |
| — | ALPINE IMMUNE SCIENCES INC | 200,000 | $2.52M | 0.0% | $8.79 | — | — | 02083G100 |
| IVA | INVENTIVA SA | 160,000 | $2.32M | 0.0% | $11.80 | — | — | 46124U107 |
| SPRY | SILVERBACK THERAPEUTICS INC | 47,620 | $2.207M | 0.0% | $33.40 | 0.0% | — | 82835W108 |
| — | BROADMARK RLTY CAP INC | 7,174,613 | $1.937M | 0.0% | $0.38 | — | — | 11135B118 |
| — | GOL LINHAS AEREAS INTELIGENT | 85,838 | $843K | 0.0% | $4.28 | — | — | 38045R206 |
| — | CEREVEL THERAPEUTICS HLDNG I | 134,175 | $758K | 0.0% | $5.65 | — | — | 15678U102 |