China Universal Asset Management Co., Ltd. Diversified Active

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
WDC	WESTERN DIGITAL CORP	13,175	$2,270	0.2%	$151.55	0.0%	Common Stock	958102105
STX	SEAGATE TECHNOLOGY HOLDINGS	6,043	$1,668	0.1%	$258.92	0.0%	Common Stock	G7997R103
ABVX	ABIVAX SA-ADR	11,619	$1,567	0.1%	$134.85	—	ADR	00370M103
FER	FERROVIAL SE	20,764	$1,342	0.1%	$63.68	0.0%	Common Stock	N3168P101
CAI	CARIS LIFE SCIENCES INC	45,976	$1,240	0.1%	$28.16	0.0%	Common Stock	142152107
MPWR	MONOLITHIC POWER SYSTEMS INC	1,356	$1,231	0.1%	$960.73	0.0%	Common Stock	609839105
VRT	VERTIV HOLDINGS CO-A	6,271	$1,016	0.1%	$173.58	0.0%	Common Stock	92537N108
TER	TERADYNE INC	5,200	$1,007	0.1%	$171.50	0.0%	Common Stock	880770102
TAK	TAKEDA PHARMACEUTIC-SP ADR	64,000	$998	0.1%	$15.59	—	ADR	874060205
TAL	TAL EDUCATION GROUP- ADR	82,000	$895	0.1%	$10.91	—	ADR	874080104
SNDK	SANDISK CORP	3,700	$878	0.1%	$200.29	0.0%	Common Stock	80004C200
CI	THE CIGNA GROUP	2,500	$688	0.1%	$279.23	0.0%	Common Stock	125523100
RDDT	REDDIT INC-CL A	2,500	$575	0.0%	$210.30	0.0%	Common Stock	75734B100
AXP	AMERICAN EXPRESS CO	1,451	$537	0.0%	$356.97	0.0%	Common Stock	025816109
NVO	NOVO-NORDISK A/S-SPONS ADR	10,000	$509	0.0%	$50.88	—	ADR	670100205
ZBIO	ZENAS BIOPHARMA INC	13,314	$483	0.0%	$32.89	0.0%	Common Stock	98937L105
MDT	MEDTRONIC PLC	5,000	$483	0.0%	$97.14	0.0%	Common Stock	G5960L103
WRD	WERIDE INC-ADR	40,000	$347	0.0%	$8.68	—	ADR	950915108
A	AGILENT TECHNOLOGIES INC	2,500	$340	0.0%	$143.72	0.0%	Common Stock	00846U101
SEPN	SEPTERNA INC	10,296	$287	0.0%	$23.88	0.0%	Common Stock	81734D104
DGX	QUEST DIAGNOSTICS INC	1,600	$278	0.0%	$182.07	0.0%	Common Stock	74834L100
KOD	KODIAK SCIENCES INC	8,644	$242	0.0%	$20.48	0.0%	Common Stock	50015M109
RMD	RESMED INC	1,000	$241	0.0%	$255.44	0.0%	Common Stock	761152107
UPB	UPSTREAM BIO INC	8,806	$239	0.0%	$24.89	0.0%	Common Stock	91678A107
VTYX	VENTYX BIOSCIENCES INC	21,628	$195	0.0%	$7.47	0.0%	Common Stock	92332V107
PODD	INSULET CORP	600	$171	0.0%	$312.66	0.0%	Common Stock	45784P101
PVLA	PALVELLA THERAPEUTICS INC	1,600	$167	0.0%	$85.31	0.0%	Common Stock	697947109
RAPT	RAPT THERAPEUTICS INC	4,515	$153	0.0%	$31.06	0.0%	Common Stock	75382E208
BCAX	BICARA THERAPEUTICS INC	8,927	$150	0.0%	$17.08	0.0%	Common Stock	055477103
GOSS	GOSSAMER BIO INC	47,716	$148	0.0%	$2.85	0.0%	Common Stock	38341P102
GHRS	GH RESEARCH PLC	10,107	$128	0.0%	$13.62	0.0%	Common Stock	G3855L106
CTMX	CYTOMX THERAPEUTICS INC	27,609	$118	0.0%	$3.80	0.0%	Common Stock	23284F105
IVVD	INVIVYD INC	45,157	$112	0.0%	$2.08	0.0%	Common Stock	00534A102
FULC	FULCRUM THERAPEUTICS INC	8,819	$100	0.0%	$10.18	0.0%	Common Stock	359616109
AXGN	AXOGEN INC	3,000	$98	0.0%	$24.59	0.0%	Common Stock	05463X106
BIOA	BIOAGE LABS INC	5,843	$77	0.0%	$8.86	0.0%	Common Stock	09077V100
ETON	ETON PHARMACEUTICALS INC	4,370	$74	0.0%	$17.60	0.0%	Common Stock	29772L108
NBP	NOVABRIDGE BIOSCIENCES	16,940	$67	0.0%	$3.98	—	ADR	44975P103
KMDA	KAMADA LTD	9,399	$66	0.0%	$6.92	0.0%	Common Stock	M6240T109
CAMP	CAMP4 THERAPEUTICS CORP	10,000	$61	0.0%	$4.25	0.0%	Common Stock	13463J101
ACRS	ACLARIS THERAPEUTICS INC	17,655	$53	0.0%	$2.53	0.0%	Common Stock	00461U105
CADL	CANDEL THERAPEUTICS INC	8,946	$51	0.0%	$5.38	0.0%	Common Stock	137404109
LFCR	LIFECORE BIOMEDICAL INC	6,105	$50	0.0%	$7.40	0.0%	Common Stock	514766104
MENS	JYONG BIOTECH LTD	12,389	$49	0.0%	$35.32	0.0%	Common Stock	G83116106
PBYI	PUMA BIOTECHNOLOGY INC	8,211	$49	0.0%	$5.31	0.0%	Common Stock	74587V107
CSIQ	CANADIAN SOLAR INC	2,000	$48	0.0%	$21.80	0.0%	Common Stock	136635109
AARD	AARDVARK THERAPEUTICS INC	3,548	$47	0.0%	$12.48	0.0%	Common Stock	002942100
VALN	VALNEVA SE - ADR	5,000	$44	0.0%	$8.82	—	ADR	92025Y103
CTNM	CONTINEUM THERAPEUTICS INC-A	3,764	$43	0.0%	$11.41	0.0%	Common Stock	21217B100
OBIO	ORCHESTRA BIOMED HOLDINGS IN	9,201	$38	0.0%	$4.03	0.0%	Common Stock	68572M106
VOR	VOR BIOPHARMA INC	2,746	$36	0.0%	$18.62	0.0%	Common Stock	929033207
QSI	QUANTUM-SI INC	31,865	$35	0.0%	$1.63	0.0%	Common Stock	74765K105
CABA	CABALETTA BIO INC	15,686	$34	0.0%	$2.48	0.0%	Common Stock	12674W109
EVMN	EVOMMUNE INC	2,000	$34	0.0%	$18.78	0.0%	Common Stock	30054Y107
UXIN	UXIN LTD - ADR	10,000	$34	0.0%	$3.37	—	ADR	91818X306
SGMT	SAGIMET BIOSCIENCES INC-A	5,052	$30	0.0%	$7.18	0.0%	Common Stock	786700104
DMAC	DIAMEDICA THERAPEUTICS INC	3,600	$29	0.0%	$7.48	0.0%	Common Stock	25253X207
CHRS	COHERUS ONCOLOGY INC	19,696	$28	0.0%	$1.46	0.0%	Common Stock	19249H103
CRBU	CARIBOU BIOSCIENCES INC	15,231	$24	0.0%	$2.10	0.0%	Common Stock	142038108
BDTX	BLACK DIAMOND THERAPEUTICS I	9,284	$23	0.0%	$3.54	0.0%	Common Stock	09203E105
RANI	RANI THERAPEUTICS HOLDINGS-A	15,894	$21	0.0%	$1.51	0.0%	Common Stock	753018100
TNYA	TENAYA THERAPEUTICS INC	27,132	$19	0.0%	$1.36	0.0%	Common Stock	87990A106
RCEL	AVITA MEDICAL INC	5,000	$17	0.0%	$3.99	0.0%	Common Stock	05380C102

Increased Positions (186)

UGL PROSHARES ULTRA GOLD 1.6%

Value ($000) $21,475 (+499.3%) Shares 386,800 (+397.2%) Est. Cost $56.03 Unrealized —

GOOGL ALPHABET INC-CL A 4.2%

Value ($000) $54,448 (+47.3%) Shares 173,954 (+14.4%) Est. Cost $166.63 Unrealized +71.4%

MU MICRON TECHNOLOGY INC 1.3%

Value ($000) $16,354 (+147.2%) Shares 57,278 (+44.8%) Est. Cost $140.44 Unrealized +63.3%

GOOG ALPHABET INC-CL C 1.8%

Value ($000) $23,211 (+34.6%) Shares 73,966 (+4.5%) Est. Cost $173.03 Unrealized +65.5%

AMGN AMGEN INC 1.8%

Value ($000) $23,414 (+28.4%) Shares 71,534 (+10.7%) Est. Cost $286.18 Unrealized +10.4%

NFLX NETFLIX INC 1.4%

Value ($000) $18,751 (-21.4%) Shares 199,990 (+905.0%) Est. Cost $103.43 Unrealized +4.2%

AMD ADVANCED MICRO DEVICES 1.2%

Value ($000) $15,077 (+49.6%) Shares 70,402 (+13.0%) Est. Cost $137.39 Unrealized +63.5%

VRTX VERTEX PHARMACEUTICALS INC 1.7%

Value ($000) $21,783 (+23.3%) Shares 48,047 (+6.5%) Est. Cost $387.33 Unrealized +11.3%

GILD GILEAD SCIENCES INC 1.7%

Value ($000) $21,593 (+20.7%) Shares 175,928 (+9.2%) Est. Cost $77.52 Unrealized +55.9%

GLDM SPDR GOLD MINISHARES TRUST 1.4%

Value ($000) $17,603 (+21.7%) Shares 206,200 (+9.0%) Est. Cost $54.49 Unrealized —

GLD SPDR GOLD SHARES 1.0%

Value ($000) $12,959 (+31.8%) Shares 32,700 (+18.2%) Est. Cost $306.17 Unrealized —

SGOL ABRDN PHYSICAL GOLD SHARES 0.6%

Value ($000) $8,360 (+55.6%) Shares 203,500 (+39.4%) Est. Cost $30.64 Unrealized —

TSLA TESLA INC 1.9%

Value ($000) $24,516 (+13.7%) Shares 54,514 (+12.4%) Est. Cost $295.53 Unrealized +50.0%

IAU ISHARES GOLD TRUST 0.5%

Value ($000) $6,250 (+86.7%) Shares 77,000 (+67.4%) Est. Cost $62.40 Unrealized —

LITE LUMENTUM HOLDINGS INC 0.3%

Value ($000) $4,202 (+203.8%) Shares 11,399 (+34.1%) Est. Cost $158.30 Unrealized +62.2%

LRCX LAM RESEARCH CORP 0.7%

Value ($000) $9,339 (+39.5%) Shares 54,487 (+9.2%) Est. Cost $90.49 Unrealized +71.7%

RACE FERRARI NV 0.2%

Value ($000) $3,136 (+522.1%) Shares 8,487 (+716.8%) Est. Cost $384.49 Unrealized +4.1%

NVS NOVARTIS AG-SPONSORED ADR 0.4%

Value ($000) $4,963 (+93.5%) Shares 36,000 (+80.0%) Est. Cost $122.12 Unrealized —

LLY ELI LILLY & CO 0.5%

Value ($000) $6,553 (+51.9%) Shares 6,098 (+7.8%) Est. Cost $535.56 Unrealized +78.4%

AZN ASTRAZENECA PLC-SPONS ADR 1.0%

Value ($000) $12,469 (+21.7%) Shares 135,636 (+1.5%) Est. Cost $71.37 Unrealized —

INSM INSMED INC 0.6%

Value ($000) $7,377 (+38.3%) Shares 42,388 (+14.4%) Est. Cost $67.38 Unrealized +170.8%

IAUM ISHARES GOLD TRUST MICRO 1.3%

Value ($000) $16,745 (+13.7%) Shares 389,500 (+1.8%) Est. Cost $28.25 Unrealized —

ISRG INTUITIVE SURGICAL INC 0.5%

Value ($000) $6,919 (+35.0%) Shares 12,217 (+6.6%) Est. Cost $402.14 Unrealized +32.4%

CSCO CISCO SYSTEMS INC 0.7%

Value ($000) $9,407 (+19.9%) Shares 122,118 (+6.5%) Est. Cost $54.95 Unrealized +34.3%

IONS IONIS PHARMACEUTICALS INC 0.3%

Value ($000) $3,354 (+83.5%) Shares 42,394 (+51.7%) Est. Cost $55.50 Unrealized +35.7%

AMAT APPLIED MATERIALS INC 0.4%

Value ($000) $5,794 (+34.6%) Shares 22,544 (+7.2%) Est. Cost $192.82 Unrealized +24.2%

SNPS SYNOPSYS INC 0.5%

Value ($000) $6,957 (+25.5%) Shares 14,810 (+31.8%) Est. Cost $458.34 Unrealized -3.1%

SHOP SHOPIFY INC - CLASS A 0.7%

Value ($000) $9,062 (+17.5%) Shares 56,298 (+8.4%) Est. Cost $101.51 Unrealized +58.2%

KLAC KLA CORP 0.8%

Value ($000) $10,022 (+14.5%) Shares 8,248 (+1.7%) Est. Cost $601.74 Unrealized +94.8%

PRAX PRAXIS PRECISION MEDICINES I 0.1%

Value ($000) $1,437 (+634.9%) Shares 4,875 (+32.1%) Est. Cost $99.59 Unrealized +87.0%

AAAU GOLDMAN SACHS PHYSICAL GOLD 0.8%

Value ($000) $10,084 (+14.0%) Shares 237,000 (+2.2%) Est. Cost $24.30 Unrealized —

INTC INTEL CORP 0.5%

Value ($000) $6,383 (+23.9%) Shares 172,985 (+12.7%) Est. Cost $27.21 Unrealized +38.8%

JNJ JOHNSON & JOHNSON 0.4%

Value ($000) $4,611 (+33.4%) Shares 22,279 (+19.5%) Est. Cost $160.09 Unrealized +23.1%

MSTR STRATEGY INC 0.1%

Value ($000) $1,151 (-48.7%) Shares 7,576 (+8.7%) Est. Cost $312.60 Unrealized -26.4%

NOW SERVICENOW INC 0.2%

Value ($000) $2,497 (-30.2%) Shares 16,300 (+319.2%) Est. Cost $163.15 Unrealized +5.1%

COHR COHERENT CORP 0.2%

Value ($000) $2,267 (+81.4%) Shares 12,284 (+5.9%) Est. Cost $102.47 Unrealized +46.0%

ROIV ROIVANT SCIENCES LTD 0.2%

Value ($000) $2,806 (+55.0%) Shares 129,330 (+8.0%) Est. Cost $11.34 Unrealized +74.0%

TSM TAIWAN SEMICONDUCTOR-SP ADR 0.6%

Value ($000) $8,189 (+13.5%) Shares 26,893 (+4.3%) Est. Cost $136.51 Unrealized —

DDOG DATADOG INC - CLASS A 0.2%

Value ($000) $2,082 (+71.3%) Shares 15,310 (+79.4%) Est. Cost $124.02 Unrealized +27.4%

ADI ANALOG DEVICES INC 0.6%

Value ($000) $8,192 (+11.7%) Shares 30,207 (+1.2%) Est. Cost $210.46 Unrealized +19.1%

TCOM TRIP.COM GROUP LTD-ADR 0.3%

Value ($000) $3,429 (+32.2%) Shares 47,685 (+38.2%) Est. Cost $50.75 Unrealized —

BKNG BOOKING HOLDINGS INC 0.6%

Value ($000) $8,151 (+11.3%) Shares 1,522 (+12.2%) Est. Cost $3518.91 Unrealized +46.0%

PDD PDD HOLDINGS INC 0.3%

Value ($000) $4,541 (+21.2%) Shares 40,052 (+41.2%) Est. Cost $116.81 Unrealized —

RNA AVIDITY BIOSCIENCES INC 0.1%

Value ($000) $1,771 (+80.2%) Shares 24,553 (+8.9%) Est. Cost $31.98 Unrealized +102.0%

BZ KANZHUN LTD - ADR 0.1%

Value ($000) $1,162 (+187.4%) Shares 57,000 (+229.5%) Est. Cost $20.92 Unrealized —

WBD WARNER BROS DISCOVERY INC 0.2%

Value ($000) $2,021 (+58.3%) Shares 70,123 (+7.3%) Est. Cost $11.00 Unrealized +112.4%

ASML ASML HOLDING NV-NY REG SHS 0.2%

Value ($000) $3,192 (+30.0%) Shares 2,984 (+17.6%) Est. Cost $921.34 Unrealized —

DASH DOORDASH INC - A 0.4%

Value ($000) $4,812 (-13.1%) Shares 21,249 (+4.3%) Est. Cost $160.60 Unrealized +46.1%

TMUS T-MOBILE US INC 0.5%

Value ($000) $6,427 (-9.6%) Shares 31,652 (+6.5%) Est. Cost $212.25 Unrealized -0.4%

KYMR KYMERA THERAPEUTICS INC 0.1%

Value ($000) $1,908 (+49.6%) Shares 24,524 (+8.8%) Est. Cost $37.48 Unrealized +80.2%

V VISA INC-CLASS A SHARES 0.9%

Value ($000) $11,198 (+5.3%) Shares 31,929 (+2.5%) Est. Cost $243.29 Unrealized +39.9%

PLTR PALANTIR TECHNOLOGIES INC-A 1.2%

Value ($000) $16,011 (+3.6%) Shares 90,077 (+6.3%) Est. Cost $89.93 Unrealized +101.3%

PEP PEPSICO INC 0.5%

Value ($000) $6,117 (+9.9%) Shares 42,259 (+6.6%) Est. Cost $154.97 Unrealized -5.9%

COGT COGENT BIOSCIENCES INC 0.1%

Value ($000) $888 (+152.7%) Shares 25,014 (+2.2%) Est. Cost $9.28 Unrealized +202.9%

SYK STRYKER CORP 0.1%

Value ($000) $1,268 (+71.2%) Shares 3,600 (+80.0%) Est. Cost $375.16 Unrealized -3.1%

PANW PALO ALTO NETWORKS INC 0.5%

Value ($000) $6,912 (-6.9%) Shares 37,524 (+2.9%) Est. Cost $155.59 Unrealized +29.7%

MELI MERCADOLIBRE INC 0.4%

Value ($000) $4,582 (-10.0%) Shares 2,275 (+4.5%) Est. Cost $2051.72 Unrealized +2.4%

MAR MARRIOTT INTERNATIONAL -CL A 0.2%

Value ($000) $2,356 (+26.2%) Shares 7,594 (+6.0%) Est. Cost $251.20 Unrealized +13.6%

GPCR STRUCTURE THERAPEUTICS INC 0.1%

Value ($000) $757 (+159.0%) Shares 10,888 (+4.3%) Est. Cost $42.62 Unrealized —

QCOM QUALCOMM INC 0.4%

Value ($000) $5,526 (+9.0%) Shares 32,308 (+6.0%) Est. Cost $152.37 Unrealized +12.1%

MAZE MAZE THERAPEUTICS INC 0.0%

Value ($000) $474 (+814.0%) Shares 11,441 (+472.1%) Est. Cost $31.31 Unrealized +9.8%

BMY BRISTOL-MYERS SQUIBB CO 0.1%

Value ($000) $863 (+91.4%) Shares 16,000 (+60.0%) Est. Cost $46.27 Unrealized +2.7%

CEG CONSTELLATION ENERGY 0.2%

Value ($000) $3,122 (+15.0%) Shares 8,837 (+7.2%) Est. Cost $238.05 Unrealized +52.6%

RPRX ROYALTY PHARMA PLC- CL A 0.2%

Value ($000) $3,077 (+15.1%) Shares 79,620 (+5.1%) Est. Cost $29.00 Unrealized +31.5%

MBX MBX BIOSCIENCES INC 0.0%

Value ($000) $483 (+452.1%) Shares 15,317 (+206.3%) Est. Cost $20.71 Unrealized +17.2%

MNST MONSTER BEVERAGE CORP 0.2%

Value ($000) $2,120 (+22.2%) Shares 27,648 (+7.3%) Est. Cost $55.18 Unrealized +29.9%

NAMS NEWAMSTERDAM PHARMA CO NV 0.1%

Value ($000) $929 (+65.4%) Shares 26,477 (+34.1%) Est. Cost $25.12 Unrealized +44.9%

APGE APOGEE THERAPEUTICS INC 0.1%

Value ($000) $674 (+110.0%) Shares 8,935 (+10.6%) Est. Cost $39.08 Unrealized +61.2%

INTU INTUIT INC 0.7%

Value ($000) $9,076 (+4.0%) Shares 13,702 (+7.2%) Est. Cost $647.13 Unrealized +2.1%

ALNY ALNYLAM PHARMACEUTICALS INC 0.8%

Value ($000) $10,047 (-3.3%) Shares 25,267 (+10.9%) Est. Cost $224.54 Unrealized +97.1%

ROST ROSS STORES INC 0.1%

Value ($000) $1,658 (+25.7%) Shares 9,203 (+6.6%) Est. Cost $139.58 Unrealized +19.4%

SRRK SCHOLAR ROCK HOLDING CORP 0.1%

Value ($000) $952 (+51.8%) Shares 21,622 (+28.3%) Est. Cost $20.93 Unrealized +79.2%

QURE UNIQURE NV 0.0%

Value ($000) $243 (-56.7%) Shares 10,150 (+5.5%) Est. Cost $10.10 Unrealized +282.0%

CRWD CROWDSTRIKE HOLDINGS INC - A 0.4%

Value ($000) $4,642 (+7.3%) Shares 9,902 (+12.2%) Est. Cost $365.00 Unrealized +39.5%

LIN LINDE PLC 0.5%

Value ($000) $6,156 (-4.6%) Shares 14,437 (+6.3%) Est. Cost $442.69 Unrealized -3.5%

PCAR PACCAR INC 0.1%

Value ($000) $1,645 (+20.7%) Shares 14,863 (+7.2%) Est. Cost $97.79 Unrealized +3.5%

SION SIONNA THERAPEUTICS INC 0.0%

Value ($000) $423 (+187.4%) Shares 10,272 (+105.4%) Est. Cost $30.05 Unrealized +26.2%

IMCR IMMUNOCORE HOLDINGS PLC-ADR 0.0%

Value ($000) $524 (+105.6%) Shares 15,109 (+115.2%) Est. Cost $41.18 Unrealized —

CTSH COGNIZANT TECH SOLUTIONS-A 0.1%

Value ($000) $1,134 (+31.1%) Shares 13,658 (+5.9%) Est. Cost $74.56 Unrealized +0.1%

META META PLATFORMS INC-CLASS A 2.8%

Value ($000) $36,146 (+0.7%) Shares 54,759 (+12.1%) Est. Cost $384.04 Unrealized +73.8%

ABNB AIRBNB INC-CLASS A 0.1%

Value ($000) $1,633 (+18.8%) Shares 12,035 (+6.3%) Est. Cost $134.87 Unrealized -7.7%

CDNS CADENCE DESIGN SYS INC 0.3%

Value ($000) $3,471 (-6.7%) Shares 11,103 (+4.8%) Est. Cost $287.85 Unrealized +13.4%

SYRE SPYRE THERAPEUTICS INC 0.0%

Value ($000) $414 (+133.4%) Shares 12,644 (+19.4%) Est. Cost $28.80 Unrealized -9.3%

ORLY O'REILLY AUTOMOTIVE INC 0.2%

Value ($000) $2,179 (-9.8%) Shares 23,887 (+6.6%) Est. Cost $91.94 Unrealized +6.3%

DXCM DEXCOM INC 0.1%

Value ($000) $932 (+33.7%) Shares 14,037 (+35.6%) Est. Cost $83.10 Unrealized -22.2%

CHTR CHARTER COMMUNICATIONS INC-A 0.1%

Value ($000) $764 (-22.9%) Shares 3,662 (+1.6%) Est. Cost $339.89 Unrealized -33.8%

EYPT EYEPOINT INC 0.0%

Value ($000) $539 (+71.3%) Shares 29,490 (+33.5%) Est. Cost $12.97 Unrealized +9.3%

AXON AXON ENTERPRISE INC 0.1%

Value ($000) $1,268 (-14.7%) Shares 2,233 (+7.8%) Est. Cost $589.99 Unrealized +5.2%

PHVS PHARVARIS NV 0.0%

Value ($000) $290 (+287.0%) Shares 10,438 (+247.9%) Est. Cost $23.54 Unrealized +2.3%

OLMA OLEMA PHARMACEUTICALS INC 0.0%

Value ($000) $325 (+176.3%) Shares 13,018 (+8.2%) Est. Cost $11.83 Unrealized +50.5%

ADP AUTOMATIC DATA PROCESSING 0.2%

Value ($000) $2,961 (-6.1%) Shares 11,445 (+7.0%) Est. Cost $271.06 Unrealized -2.3%

NIO NIO INC - ADR 0.0%

Value ($000) $383 (+100.8%) Shares 75,000 (+200.0%) Est. Cost $5.94 Unrealized —

NRIX NURIX THERAPEUTICS INC 0.0%

Value ($000) $313 (+153.1%) Shares 16,518 (+23.3%) Est. Cost $16.02 Unrealized -10.3%

TRI THOMSON REUTERS CORP 0.1%

Value ($000) $1,660 (-10.2%) Shares 12,588 (+5.8%) Est. Cost $178.96 Unrealized -21.1%

STOK STOKE THERAPEUTICS INC 0.0%

Value ($000) $410 (+81.5%) Shares 12,907 (+34.4%) Est. Cost $16.77 Unrealized +79.3%

FAST FASTENAL CO 0.1%

Value ($000) $1,304 (-12.3%) Shares 32,488 (+7.2%) Est. Cost $38.73 Unrealized +8.5%

IDXX IDEXX LABORATORIES INC 0.1%

Value ($000) $1,529 (+13.3%) Shares 2,260 (+7.0%) Est. Cost $487.05 Unrealized +39.8%

TEAM ATLASSIAN CORP-CL A 0.1%

Value ($000) $1,306 (+15.3%) Shares 8,055 (+13.6%) Est. Cost $213.83 Unrealized -26.6%

SBUX STARBUCKS CORP 0.2%

Value ($000) $2,718 (+6.7%) Shares 32,274 (+7.2%) Est. Cost $91.61 Unrealized -8.2%

NKE NIKE INC -CL B 0.2%

Value ($000) $2,510 (-6.3%) Shares 39,203 (+2.2%) Est. Cost $72.33 Unrealized -10.3%

MDLZ MONDELEZ INTERNATIONAL INC-A 0.2%

Value ($000) $1,982 (-7.8%) Shares 36,515 (+6.9%) Est. Cost $63.73 Unrealized -10.5%

CSX CSX CORP 0.1%

Value ($000) $1,910 (+9.3%) Shares 52,696 (+7.1%) Est. Cost $33.01 Unrealized +8.1%

MRVL MARVELL TECHNOLOGY INC 0.2%

Value ($000) $2,073 (+8.4%) Shares 24,396 (+7.2%) Est. Cost $81.77 Unrealized +7.0%

KDP KEURIG DR PEPPER INC 0.1%

Value ($000) $1,077 (+16.8%) Shares 38,446 (+7.2%) Est. Cost $31.46 Unrealized -13.4%

AEP AMERICAN ELECTRIC POWER 0.1%

Value ($000) $1,743 (+9.7%) Shares 15,114 (+7.1%) Est. Cost $95.19 Unrealized +23.6%

GEHC GE HEALTHCARE TECHNOLOGY 0.1%

Value ($000) $1,057 (+16.8%) Shares 12,891 (+7.0%) Est. Cost $82.11 Unrealized -5.1%

HUM HUMANA INC 0.0%

Value ($000) $411 (+57.5%) Shares 1,600 (+60.0%) Est. Cost $261.25 Unrealized +0.0%

ODFL OLD DOMINION FREIGHT LINE 0.1%

Value ($000) $928 (+18.8%) Shares 5,917 (+6.7%) Est. Cost $183.36 Unrealized -21.9%

IRON DISC MEDICINE INC 0.0%

Value ($000) $616 (+31.3%) Shares 7,751 (+9.3%) Est. Cost $55.53 Unrealized +52.2%

HD HOME DEPOT INC 0.4%

Value ($000) $4,776 (+3.2%) Shares 13,881 (+21.5%) Est. Cost $322.34 Unrealized +13.1%

PYPL PAYPAL HOLDINGS INC 0.1%

Value ($000) $1,546 (-8.6%) Shares 26,478 (+5.0%) Est. Cost $74.24 Unrealized -12.7%

CSGP COSTAR GROUP INC 0.1%

Value ($000) $806 (-14.5%) Shares 11,994 (+7.2%) Est. Cost $78.79 Unrealized -10.1%

SAP SAP SE-SPONSORED ADR 0.2%

Value ($000) $2,429 (+5.7%) Shares 10,000 (+16.3%) Est. Cost $233.04 Unrealized —

CAT CATERPILLAR INC 0.1%

Value ($000) $699 (+22.2%) Shares 1,221 (+1.8%) Est. Cost $427.63 Unrealized +29.9%

FANG DIAMONDBACK ENERGY INC 0.1%

Value ($000) $1,219 (+11.5%) Shares 8,108 (+6.1%) Est. Cost $162.25 Unrealized -9.4%

WMT WALMART INC 0.1%

Value ($000) $1,276 (+10.6%) Shares 11,433 (+2.1%) Est. Cost $71.44 Unrealized +50.1%

MCK MCKESSON CORP 0.1%

Value ($000) $1,314 (+9.7%) Shares 1,600 (+3.4%) Est. Cost $622.38 Unrealized +31.0%

LOW LOWE'S COS INC 0.1%

Value ($000) $1,355 (+9.2%) Shares 5,620 (+13.8%) Est. Cost $212.96 Unrealized +12.6%

EA ELECTRONIC ARTS INC 0.1%

Value ($000) $1,446 (+8.6%) Shares 7,078 (+7.2%) Est. Cost $146.36 Unrealized +37.8%

ORKA ORUKA THERAPEUTICS INC 0.0%

Value ($000) $239 (+89.4%) Shares 7,888 (+20.2%) Est. Cost $24.86 Unrealized +12.1%

ADSK AUTODESK INC 0.2%

Value ($000) $3,019 (-3.5%) Shares 10,199 (+3.6%) Est. Cost $282.67 Unrealized +7.0%

RAPP RAPPORT THERAPEUTICS INC 0.0%

Value ($000) $327 (+48.7%) Shares 10,766 (+45.5%) Est. Cost $23.88 Unrealized +15.9%

XOM EXXON MOBIL CORP 0.1%

Value ($000) $1,338 (+7.9%) Shares 11,116 (+1.1%) Est. Cost $107.01 Unrealized +7.9%

SNOW SNOWFLAKE INC 0.1%

Value ($000) $1,338 (+7.9%) Shares 6,100 (+10.9%) Est. Cost $197.04 Unrealized +23.9%

SVRA SAVARA INC 0.0%

Value ($000) $200 (+84.8%) Shares 33,155 (+9.4%) Est. Cost $4.27 Unrealized +14.7%

WFC WELLS FARGO & CO 0.1%

Value ($000) $778 (+13.0%) Shares 8,352 (+1.7%) Est. Cost $58.17 Unrealized +48.9%

CCEP COCA-COLA EUROPACIFIC PARTNE 0.1%

Value ($000) $1,176 (+7.5%) Shares 12,966 (+7.2%) Est. Cost $76.67 Unrealized +16.9%

ARM ARM HOLDINGS PLC-ADR 0.0%

Value ($000) $428 (-16.1%) Shares 3,915 (+8.6%) Est. Cost $130.05 Unrealized —

TTWO TAKE-TWO INTERACTIVE SOFTWRE 0.1%

Value ($000) $1,339 (+6.4%) Shares 5,229 (+7.4%) Est. Cost $186.07 Unrealized +34.0%

CRM SALESFORCE INC 0.1%

Value ($000) $658 (+13.7%) Shares 2,482 (+1.8%) Est. Cost $259.40 Unrealized -4.3%

CPRT COPART INC 0.1%

Value ($000) $1,072 (-6.6%) Shares 27,394 (+7.3%) Est. Cost $51.93 Unrealized -20.1%

ANNX ANNEXON INC 0.0%

Value ($000) $181 (+68.4%) Shares 36,084 (+2.3%) Est. Cost $4.68 Unrealized -18.3%

JPM JPMORGAN CHASE & CO 0.2%

Value ($000) $2,310 (+3.3%) Shares 7,169 (+1.1%) Est. Cost $207.32 Unrealized +49.3%

RTX RTX CORP 0.0%

Value ($000) $640 (+12.2%) Shares 3,490 (+2.4%) Est. Cost $154.73 Unrealized +12.0%

PGEN PRECIGEN INC 0.0%

Value ($000) $241 (+40.3%) Shares 57,656 (+10.4%) Est. Cost $1.50 Unrealized +157.7%

BRK/B BERKSHIRE HATHAWAY INC-CL B 0.1%

Value ($000) $1,807 (+3.9%) Shares 3,594 (+4.0%) Est. Cost $440.75 Unrealized +12.9%

GMAB GENMAB A/S -SP ADR 0.0%

Value ($000) $293 (+30.1%) Shares 9,525 (+29.6%) Est. Cost $23.39 Unrealized —

IMRX IMMUNEERING CORP - CLASS A 0.0%

Value ($000) $102 (+191.8%) Shares 15,522 (+210.4%) Est. Cost $6.02 Unrealized +6.6%

ROP ROPER TECHNOLOGIES INC 0.1%

Value ($000) $1,356 (-4.3%) Shares 3,046 (+7.2%) Est. Cost $537.42 Unrealized -14.0%

PAYX PAYCHEX INC 0.1%

Value ($000) $1,143 (-5.1%) Shares 10,185 (+7.3%) Est. Cost $129.44 Unrealized -10.0%

MCHP MICROCHIP TECHNOLOGY INC 0.1%

Value ($000) $975 (+6.5%) Shares 15,294 (+7.3%) Est. Cost $68.51 Unrealized -10.4%

— DEFINIUM THERAPEUTICS INC 0.0%

Value ($000) $215 (+36.7%) Shares 16,052 (+20.4%) Est. Cost $8.04 Unrealized —

SPOT SPOTIFY TECHNOLOGY SA 0.1%

Value ($000) $1,278 (+4.6%) Shares 2,200 (+25.7%) Est. Cost $598.53 Unrealized +4.4%

LXEO LEXEO THERAPEUTICS INC 0.0%

Value ($000) $118 (+87.9%) Shares 11,893 (+25.6%) Est. Cost $7.42 Unrealized +23.1%

LYEL LYELL IMMUNOPHARMA INC 0.0%

Value ($000) $106 (+94.6%) Shares 3,457 (+2.7%) Est. Cost $9.73 Unrealized +130.1%

TXN TEXAS INSTRUMENTS INC 0.3%

Value ($000) $4,461 (+1.2%) Shares 25,713 (+7.1%) Est. Cost $182.45 Unrealized -6.4%

IBM INTL BUSINESS MACHINES CORP 0.1%

Value ($000) $719 (+7.5%) Shares 2,429 (+2.4%) Est. Cost $199.24 Unrealized +50.0%

ESPR ESPERION THERAPEUTICS INC 0.0%

Value ($000) $144 (+53.9%) Shares 38,955 (+10.2%) Est. Cost $2.42 Unrealized +33.7%

KO COCA-COLA CO/THE 0.1%

Value ($000) $745 (+7.0%) Shares 10,660 (+2.2%) Est. Cost $62.51 Unrealized +11.0%

PEPG PEPGEN INC 0.0%

Value ($000) $73 (+174.6%) Shares 11,202 (+94.9%) Est. Cost $5.72 Unrealized -9.3%

EXC EXELON CORP 0.1%

Value ($000) $1,246 (+3.8%) Shares 28,590 (+7.2%) Est. Cost $38.73 Unrealized +17.4%

VRSK VERISK ANALYTICS INC 0.1%

Value ($000) $882 (-4.9%) Shares 3,944 (+6.9%) Est. Cost $264.96 Unrealized -15.0%

CTAS CINTAS CORP 0.2%

Value ($000) $2,139 (-2.1%) Shares 11,372 (+6.9%) Est. Cost $195.23 Unrealized -3.6%

UNH UNITEDHEALTH GROUP INC 0.1%

Value ($000) $1,308 (-3.3%) Shares 3,961 (+1.2%) Est. Cost $465.61 Unrealized -27.6%

CRVS CORVUS PHARMACEUTICALS INC 0.0%

Value ($000) $140 (+45.3%) Shares 18,169 (+39.1%) Est. Cost $7.12 Unrealized +10.7%

CRSP CRISPR THERAPEUTICS AG 0.1%

Value ($000) $1,077 (+4.2%) Shares 20,529 (+28.8%) Est. Cost $57.61 Unrealized +4.0%

INVA INNOVIVA INC 0.0%

Value ($000) $244 (+20.8%) Shares 12,184 (+10.3%) Est. Cost $16.65 Unrealized +17.3%

ABSI ABSCI CORP 0.0%

Value ($000) $120 (+51.1%) Shares 34,503 (+31.6%) Est. Cost $3.48 Unrealized +4.6%

SLN SILENCE THERAPEUTICS PLC-ADR 0.0%

Value ($000) $83 (+94.3%) Shares 13,653 (+65.9%) Est. Cost $6.56 Unrealized —

IOVA IOVANCE BIOTHERAPEUTICS INC 0.0%

Value ($000) $177 (+28.3%) Shares 64,686 (+2.0%) Est. Cost $8.60 Unrealized -73.1%

GE GENERAL ELECTRIC 0.1%

Value ($000) $853 (+4.1%) Shares 2,765 (+1.7%) Est. Cost $175.20 Unrealized +71.7%

TNGX TANGO THERAPEUTICS INC 0.0%

Value ($000) $194 (+18.7%) Shares 21,946 (+12.5%) Est. Cost $8.87 Unrealized -2.9%

NXPI NXP SEMICONDUCTORS NV 0.1%

Value ($000) $1,552 (+2.0%) Shares 7,122 (+7.0%) Est. Cost $222.36 Unrealized -3.9%

AMN AMN HEALTHCARE SERVICES INC 0.0%

Value ($000) $47 (+144.2%) Shares 3,000 (+200.0%) Est. Cost $18.41 Unrealized -3.0%

MLYS MINERALYS THERAPEUTICS INC 0.0%

Value ($000) $468 (+6.2%) Shares 12,896 (+11.0%) Est. Cost $14.51 Unrealized +176.3%

ABT ABBOTT LABORATORIES 0.0%

Value ($000) $569 (-4.4%) Shares 4,538 (+2.3%) Est. Cost $114.79 Unrealized +10.9%

HON HONEYWELL INTERNATIONAL INC 0.3%

Value ($000) $3,505 (-0.7%) Shares 17,966 (+7.2%) Est. Cost $193.88 Unrealized +0.6%

RXRX RECURSION PHARMACEUTICALS-A 0.0%

Value ($000) $343 (-6.2%) Shares 83,787 (+11.9%) Est. Cost $7.38 Unrealized -32.9%

OCS OCULIS HOLDING AG 0.0%

Value ($000) $40 (+127.2%) Shares 2,000 (+100.0%) Est. Cost $18.86 Unrealized +6.0%

XEL XCEL ENERGY INC 0.1%

Value ($000) $1,245 (-1.7%) Shares 16,740 (+7.2%) Est. Cost $63.29 Unrealized +23.7%

SRZN SURROZEN INC 0.0%

Value ($000) $34 (+163.1%) Shares 1,500 (+50.0%) Est. Cost $12.38 Unrealized +30.6%

CMCSA COMCAST CORP-CLASS A 0.2%

Value ($000) $3,074 (+0.6%) Shares 102,850 (+5.8%) Est. Cost $36.78 Unrealized -22.4%

HUMA HUMACYTE INC 0.0%

Value ($000) $29 (-39.3%) Shares 30,516 (+9.9%) Est. Cost $3.81 Unrealized -62.8%

BNTX BIONTECH SE-ADR 0.1%

Value ($000) $1,721 (-1.1%) Shares 18,075 (+2.5%) Est. Cost $110.83 Unrealized —

PM PHILIP MORRIS INTERNATIONAL 0.1%

Value ($000) $656 (+1.9%) Shares 4,058 (+2.2%) Est. Cost $116.24 Unrealized +32.1%

DIS WALT DISNEY CO/THE 0.0%

Value ($000) $537 (+2.2%) Shares 4,688 (+2.2%) Est. Cost $105.71 Unrealized +3.6%

CCRN CROSS COUNTRY HEALTHCARE INC 0.0%

Value ($000) $24 (+71.1%) Shares 3,000 (+200.0%) Est. Cost $11.69 Unrealized -6.5%

OABI OMNIAB INC 0.0%

Value ($000) $43 (+26.1%) Shares 23,457 (+9.1%) Est. Cost $4.49 Unrealized -61.3%

AMLX AMYLYX PHARMACEUTICALS INC 0.0%

Value ($000) $216 (+1.8%) Shares 17,895 (+14.5%) Est. Cost $9.54 Unrealized +42.4%

BKR BAKER HUGHES CO 0.1%

Value ($000) $1,272 (+0.3%) Shares 27,924 (+7.3%) Est. Cost $38.87 Unrealized +21.8%

ALT ALTIMMUNE INC 0.0%

Value ($000) $61 (+5.2%) Shares 17,003 (+9.9%) Est. Cost $7.21 Unrealized -39.6%

XLY SS CONSUMER DISC SELECT SECT 0.1%

Value ($000) $720 (-0.3%) Shares 6,030 (+100.0%) Est. Cost $158.76 Unrealized —

CCCC C4 THERAPEUTICS INC 0.0%

Value ($000) $30 (+8.9%) Shares 15,792 (+26.6%) Est. Cost $4.43 Unrealized -46.5%

WDAY WORKDAY INC-CLASS A 0.2%

Value ($000) $2,401 (-0.1%) Shares 11,178 (+12.0%) Est. Cost $256.90 Unrealized -11.6%

KHC KRAFT HEINZ CO/THE 0.1%

Value ($000) $812 (-0.2%) Shares 33,496 (+7.2%) Est. Cost $29.67 Unrealized -17.0%

FDMT 4D MOLECULAR THERAPEUTICS IN 0.0%

Value ($000) $70 (-1.8%) Shares 9,310 (+13.7%) Est. Cost $17.28 Unrealized -41.3%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
UGL	PROSHARES ULTRA GOLD	386,800 (+397.2%)	$21,475 (+499.3%)	1.6%	$56.03	—	ETP	74347W601
GOOGL	ALPHABET INC-CL A	173,954 (+14.4%)	$54,448 (+47.3%)	4.2%	$166.63	+71.4%	Common Stock	02079K305
MU	MICRON TECHNOLOGY INC	57,278 (+44.8%)	$16,354 (+147.2%)	1.3%	$140.44	+63.3%	Common Stock	595112103
GOOG	ALPHABET INC-CL C	73,966 (+4.5%)	$23,211 (+34.6%)	1.8%	$173.03	+65.5%	Common Stock	02079K107
AMGN	AMGEN INC	71,534 (+10.7%)	$23,414 (+28.4%)	1.8%	$286.18	+10.4%	Common Stock	031162100
NFLX	NETFLIX INC	199,990 (+905.0%)	$18,751 (-21.4%)	1.4%	$103.43	+4.2%	Common Stock	64110L106
AMD	ADVANCED MICRO DEVICES	70,402 (+13.0%)	$15,077 (+49.6%)	1.2%	$137.39	+63.5%	Common Stock	007903107
VRTX	VERTEX PHARMACEUTICALS INC	48,047 (+6.5%)	$21,783 (+23.3%)	1.7%	$387.33	+11.3%	Common Stock	92532F100
GILD	GILEAD SCIENCES INC	175,928 (+9.2%)	$21,593 (+20.7%)	1.7%	$77.52	+55.9%	Common Stock	375558103
GLDM	SPDR GOLD MINISHARES TRUST	206,200 (+9.0%)	$17,603 (+21.7%)	1.4%	$54.49	—	ETP	98149E303
GLD	SPDR GOLD SHARES	32,700 (+18.2%)	$12,959 (+31.8%)	1.0%	$306.17	—	ETP	78463V107
SGOL	ABRDN PHYSICAL GOLD SHARES	203,500 (+39.4%)	$8,360 (+55.6%)	0.6%	$30.64	—	ETP	00326A104
TSLA	TESLA INC	54,514 (+12.4%)	$24,516 (+13.7%)	1.9%	$295.53	+50.0%	Common Stock	88160R101
IAU	ISHARES GOLD TRUST	77,000 (+67.4%)	$6,250 (+86.7%)	0.5%	$62.40	—	ETP	464285204
LITE	LUMENTUM HOLDINGS INC	11,399 (+34.1%)	$4,202 (+203.8%)	0.3%	$158.30	+62.2%	Common Stock	55024U109
LRCX	LAM RESEARCH CORP	54,487 (+9.2%)	$9,339 (+39.5%)	0.7%	$90.49	+71.7%	Common Stock	512807306
RACE	FERRARI NV	8,487 (+716.8%)	$3,136 (+522.1%)	0.2%	$384.49	+4.1%	Common Stock	N3167Y103
NVS	NOVARTIS AG-SPONSORED ADR	36,000 (+80.0%)	$4,963 (+93.5%)	0.4%	$122.12	—	ADR	66987V109
LLY	ELI LILLY & CO	6,098 (+7.8%)	$6,553 (+51.9%)	0.5%	$535.56	+78.4%	Common Stock	532457108
AZN	ASTRAZENECA PLC-SPONS ADR	135,636 (+1.5%)	$12,469 (+21.7%)	1.0%	$71.37	—	ADR	046353108
INSM	INSMED INC	42,388 (+14.4%)	$7,377 (+38.3%)	0.6%	$67.38	+170.8%	Common Stock	457669307
IAUM	ISHARES GOLD TRUST MICRO	389,500 (+1.8%)	$16,745 (+13.7%)	1.3%	$28.25	—	ETP	46436F103
ISRG	INTUITIVE SURGICAL INC	12,217 (+6.6%)	$6,919 (+35.0%)	0.5%	$402.14	+32.4%	Common Stock	46120E602
CSCO	CISCO SYSTEMS INC	122,118 (+6.5%)	$9,407 (+19.9%)	0.7%	$54.95	+34.3%	Common Stock	17275R102
IONS	IONIS PHARMACEUTICALS INC	42,394 (+51.7%)	$3,354 (+83.5%)	0.3%	$55.50	+35.7%	Common Stock	462222100
AMAT	APPLIED MATERIALS INC	22,544 (+7.2%)	$5,794 (+34.6%)	0.4%	$192.82	+24.2%	Common Stock	038222105
SNPS	SYNOPSYS INC	14,810 (+31.8%)	$6,957 (+25.5%)	0.5%	$458.34	-3.1%	Common Stock	871607107
SHOP	SHOPIFY INC - CLASS A	56,298 (+8.4%)	$9,062 (+17.5%)	0.7%	$101.51	+58.2%	Common Stock	82509L107
KLAC	KLA CORP	8,248 (+1.7%)	$10,022 (+14.5%)	0.8%	$601.74	+94.8%	Common Stock	482480100
PRAX	PRAXIS PRECISION MEDICINES I	4,875 (+32.1%)	$1,437 (+634.9%)	0.1%	$99.59	+87.0%	Common Stock	74006W207
AAAU	GOLDMAN SACHS PHYSICAL GOLD	237,000 (+2.2%)	$10,084 (+14.0%)	0.8%	$24.30	—	ETP	38150K103
INTC	INTEL CORP	172,985 (+12.7%)	$6,383 (+23.9%)	0.5%	$27.21	+38.8%	Common Stock	458140100
JNJ	JOHNSON & JOHNSON	22,279 (+19.5%)	$4,611 (+33.4%)	0.4%	$160.09	+23.1%	Common Stock	478160104
MSTR	STRATEGY INC	7,576 (+8.7%)	$1,151 (-48.7%)	0.1%	$312.60	-26.4%	Common Stock	594972408
NOW	SERVICENOW INC	16,300 (+319.2%)	$2,497 (-30.2%)	0.2%	$163.15	+5.1%	Common Stock	81762P102
COHR	COHERENT CORP	12,284 (+5.9%)	$2,267 (+81.4%)	0.2%	$102.47	+46.0%	Common Stock	19247G107
ROIV	ROIVANT SCIENCES LTD	129,330 (+8.0%)	$2,806 (+55.0%)	0.2%	$11.34	+74.0%	Common Stock	G76279101
TSM	TAIWAN SEMICONDUCTOR-SP ADR	26,893 (+4.3%)	$8,189 (+13.5%)	0.6%	$136.51	—	ADR	874039100
DDOG	DATADOG INC - CLASS A	15,310 (+79.4%)	$2,082 (+71.3%)	0.2%	$124.02	+27.4%	Common Stock	23804L103
ADI	ANALOG DEVICES INC	30,207 (+1.2%)	$8,192 (+11.7%)	0.6%	$210.46	+19.1%	Common Stock	032654105
TCOM	TRIP.COM GROUP LTD-ADR	47,685 (+38.2%)	$3,429 (+32.2%)	0.3%	$50.75	—	ADR	89677Q107
BKNG	BOOKING HOLDINGS INC	1,522 (+12.2%)	$8,151 (+11.3%)	0.6%	$3518.91	+46.0%	Common Stock	09857L108
PDD	PDD HOLDINGS INC	40,052 (+41.2%)	$4,541 (+21.2%)	0.3%	$116.81	—	ADR	722304102
RNA	AVIDITY BIOSCIENCES INC	24,553 (+8.9%)	$1,771 (+80.2%)	0.1%	$31.98	+102.0%	Common Stock	05370A108
BZ	KANZHUN LTD - ADR	57,000 (+229.5%)	$1,162 (+187.4%)	0.1%	$20.92	—	ADR	48553T106
WBD	WARNER BROS DISCOVERY INC	70,123 (+7.3%)	$2,021 (+58.3%)	0.2%	$11.00	+112.4%	Common Stock	934423104
ASML	ASML HOLDING NV-NY REG SHS	2,984 (+17.6%)	$3,192 (+30.0%)	0.2%	$921.34	—	NY Reg Shrs	N07059210
DASH	DOORDASH INC - A	21,249 (+4.3%)	$4,812 (-13.1%)	0.4%	$160.60	+46.1%	Common Stock	25809K105
TMUS	T-MOBILE US INC	31,652 (+6.5%)	$6,427 (-9.6%)	0.5%	$212.25	-0.4%	Common Stock	872590104
KYMR	KYMERA THERAPEUTICS INC	24,524 (+8.8%)	$1,908 (+49.6%)	0.1%	$37.48	+80.2%	Common Stock	501575104
V	VISA INC-CLASS A SHARES	31,929 (+2.5%)	$11,198 (+5.3%)	0.9%	$243.29	+39.9%	Common Stock	92826C839
PLTR	PALANTIR TECHNOLOGIES INC-A	90,077 (+6.3%)	$16,011 (+3.6%)	1.2%	$89.93	+101.3%	Common Stock	69608A108
PEP	PEPSICO INC	42,259 (+6.6%)	$6,117 (+9.9%)	0.5%	$154.97	-5.9%	Common Stock	713448108
COGT	COGENT BIOSCIENCES INC	25,014 (+2.2%)	$888 (+152.7%)	0.1%	$9.28	+202.9%	Common Stock	19240Q201
SYK	STRYKER CORP	3,600 (+80.0%)	$1,268 (+71.2%)	0.1%	$375.16	-3.1%	Common Stock	863667101
PANW	PALO ALTO NETWORKS INC	37,524 (+2.9%)	$6,912 (-6.9%)	0.5%	$155.59	+29.7%	Common Stock	697435105
MELI	MERCADOLIBRE INC	2,275 (+4.5%)	$4,582 (-10.0%)	0.4%	$2051.72	+2.4%	Common Stock	58733R102
MAR	MARRIOTT INTERNATIONAL -CL A	7,594 (+6.0%)	$2,356 (+26.2%)	0.2%	$251.20	+13.6%	Common Stock	571903202
GPCR	STRUCTURE THERAPEUTICS INC	10,888 (+4.3%)	$757 (+159.0%)	0.1%	$42.62	—	ADR	86366E106
QCOM	QUALCOMM INC	32,308 (+6.0%)	$5,526 (+9.0%)	0.4%	$152.37	+12.1%	Common Stock	747525103
MAZE	MAZE THERAPEUTICS INC	11,441 (+472.1%)	$474 (+814.0%)	0.0%	$31.31	+9.8%	Common Stock	578784100
BMY	BRISTOL-MYERS SQUIBB CO	16,000 (+60.0%)	$863 (+91.4%)	0.1%	$46.27	+2.7%	Common Stock	110122108
CEG	CONSTELLATION ENERGY	8,837 (+7.2%)	$3,122 (+15.0%)	0.2%	$238.05	+52.6%	Common Stock	21037T109
RPRX	ROYALTY PHARMA PLC- CL A	79,620 (+5.1%)	$3,077 (+15.1%)	0.2%	$29.00	+31.5%	Common Stock	G7709Q104
MBX	MBX BIOSCIENCES INC	15,317 (+206.3%)	$483 (+452.1%)	0.0%	$20.71	+17.2%	Common Stock	55287L101
MNST	MONSTER BEVERAGE CORP	27,648 (+7.3%)	$2,120 (+22.2%)	0.2%	$55.18	+29.9%	Common Stock	61174X109
NAMS	NEWAMSTERDAM PHARMA CO NV	26,477 (+34.1%)	$929 (+65.4%)	0.1%	$25.12	+44.9%	Common Stock	N62509109
APGE	APOGEE THERAPEUTICS INC	8,935 (+10.6%)	$674 (+110.0%)	0.1%	$39.08	+61.2%	Common Stock	03770N101
INTU	INTUIT INC	13,702 (+7.2%)	$9,076 (+4.0%)	0.7%	$647.13	+2.1%	Common Stock	461202103
ALNY	ALNYLAM PHARMACEUTICALS INC	25,267 (+10.9%)	$10,047 (-3.3%)	0.8%	$224.54	+97.1%	Common Stock	02043Q107
ROST	ROSS STORES INC	9,203 (+6.6%)	$1,658 (+25.7%)	0.1%	$139.58	+19.4%	Common Stock	778296103
SRRK	SCHOLAR ROCK HOLDING CORP	21,622 (+28.3%)	$952 (+51.8%)	0.1%	$20.93	+79.2%	Common Stock	80706P103
QURE	UNIQURE NV	10,150 (+5.5%)	$243 (-56.7%)	0.0%	$10.10	+282.0%	Common Stock	N90064101
CRWD	CROWDSTRIKE HOLDINGS INC - A	9,902 (+12.2%)	$4,642 (+7.3%)	0.4%	$365.00	+39.5%	Common Stock	22788C105
LIN	LINDE PLC	14,437 (+6.3%)	$6,156 (-4.6%)	0.5%	$442.69	-3.5%	Common Stock	G54950103
PCAR	PACCAR INC	14,863 (+7.2%)	$1,645 (+20.7%)	0.1%	$97.79	+3.5%	Common Stock	693718108
SION	SIONNA THERAPEUTICS INC	10,272 (+105.4%)	$423 (+187.4%)	0.0%	$30.05	+26.2%	Common Stock	829401108
IMCR	IMMUNOCORE HOLDINGS PLC-ADR	15,109 (+115.2%)	$524 (+105.6%)	0.0%	$41.18	—	ADR	45258D105
CTSH	COGNIZANT TECH SOLUTIONS-A	13,658 (+5.9%)	$1,134 (+31.1%)	0.1%	$74.56	+0.1%	Common Stock	192446102
META	META PLATFORMS INC-CLASS A	54,759 (+12.1%)	$36,146 (+0.7%)	2.8%	$384.04	+73.8%	Common Stock	30303M102
ABNB	AIRBNB INC-CLASS A	12,035 (+6.3%)	$1,633 (+18.8%)	0.1%	$134.87	-7.7%	Common Stock	009066101
CDNS	CADENCE DESIGN SYS INC	11,103 (+4.8%)	$3,471 (-6.7%)	0.3%	$287.85	+13.4%	Common Stock	127387108
SYRE	SPYRE THERAPEUTICS INC	12,644 (+19.4%)	$414 (+133.4%)	0.0%	$28.80	-9.3%	Common Stock	00773J202
ORLY	O'REILLY AUTOMOTIVE INC	23,887 (+6.6%)	$2,179 (-9.8%)	0.2%	$91.94	+6.3%	Common Stock	67103H107
DXCM	DEXCOM INC	14,037 (+35.6%)	$932 (+33.7%)	0.1%	$83.10	-22.2%	Common Stock	252131107
CHTR	CHARTER COMMUNICATIONS INC-A	3,662 (+1.6%)	$764 (-22.9%)	0.1%	$339.89	-33.8%	Common Stock	16119P108
EYPT	EYEPOINT INC	29,490 (+33.5%)	$539 (+71.3%)	0.0%	$12.97	+9.3%	Common Stock	30233G209
AXON	AXON ENTERPRISE INC	2,233 (+7.8%)	$1,268 (-14.7%)	0.1%	$589.99	+5.2%	Common Stock	05464C101
PHVS	PHARVARIS NV	10,438 (+247.9%)	$290 (+287.0%)	0.0%	$23.54	+2.3%	Common Stock	N69605108
OLMA	OLEMA PHARMACEUTICALS INC	13,018 (+8.2%)	$325 (+176.3%)	0.0%	$11.83	+50.5%	Common Stock	68062P106
ADP	AUTOMATIC DATA PROCESSING	11,445 (+7.0%)	$2,961 (-6.1%)	0.2%	$271.06	-2.3%	Common Stock	053015103
NIO	NIO INC - ADR	75,000 (+200.0%)	$383 (+100.8%)	0.0%	$5.94	—	ADR	62914V106
NRIX	NURIX THERAPEUTICS INC	16,518 (+23.3%)	$313 (+153.1%)	0.0%	$16.02	-10.3%	Common Stock	67080M103
TRI	THOMSON REUTERS CORP	12,588 (+5.8%)	$1,660 (-10.2%)	0.1%	$178.96	-21.1%	Common Stock	884903808
STOK	STOKE THERAPEUTICS INC	12,907 (+34.4%)	$410 (+81.5%)	0.0%	$16.77	+79.3%	Common Stock	86150R107
FAST	FASTENAL CO	32,488 (+7.2%)	$1,304 (-12.3%)	0.1%	$38.73	+8.5%	Common Stock	311900104
IDXX	IDEXX LABORATORIES INC	2,260 (+7.0%)	$1,529 (+13.3%)	0.1%	$487.05	+39.8%	Common Stock	45168D104
TEAM	ATLASSIAN CORP-CL A	8,055 (+13.6%)	$1,306 (+15.3%)	0.1%	$213.83	-26.6%	Common Stock	049468101
SBUX	STARBUCKS CORP	32,274 (+7.2%)	$2,718 (+6.7%)	0.2%	$91.61	-8.2%	Common Stock	855244109
NKE	NIKE INC -CL B	39,203 (+2.2%)	$2,510 (-6.3%)	0.2%	$72.33	-10.3%	Common Stock	654106103
MDLZ	MONDELEZ INTERNATIONAL INC-A	36,515 (+6.9%)	$1,982 (-7.8%)	0.2%	$63.73	-10.5%	Common Stock	609207105
CSX	CSX CORP	52,696 (+7.1%)	$1,910 (+9.3%)	0.1%	$33.01	+8.1%	Common Stock	126408103
MRVL	MARVELL TECHNOLOGY INC	24,396 (+7.2%)	$2,073 (+8.4%)	0.2%	$81.77	+7.0%	Common Stock	573874104
KDP	KEURIG DR PEPPER INC	38,446 (+7.2%)	$1,077 (+16.8%)	0.1%	$31.46	-13.4%	Common Stock	49271V100
AEP	AMERICAN ELECTRIC POWER	15,114 (+7.1%)	$1,743 (+9.7%)	0.1%	$95.19	+23.6%	Common Stock	025537101
GEHC	GE HEALTHCARE TECHNOLOGY	12,891 (+7.0%)	$1,057 (+16.8%)	0.1%	$82.11	-5.1%	Common Stock	36266G107
HUM	HUMANA INC	1,600 (+60.0%)	$411 (+57.5%)	0.0%	$261.25	+0.0%	Common Stock	444859102
ODFL	OLD DOMINION FREIGHT LINE	5,917 (+6.7%)	$928 (+18.8%)	0.1%	$183.36	-21.9%	Common Stock	679580100
IRON	DISC MEDICINE INC	7,751 (+9.3%)	$616 (+31.3%)	0.0%	$55.53	+52.2%	Common Stock	254604101
HD	HOME DEPOT INC	13,881 (+21.5%)	$4,776 (+3.2%)	0.4%	$322.34	+13.1%	Common Stock	437076102
PYPL	PAYPAL HOLDINGS INC	26,478 (+5.0%)	$1,546 (-8.6%)	0.1%	$74.24	-12.7%	Common Stock	70450Y103
CSGP	COSTAR GROUP INC	11,994 (+7.2%)	$806 (-14.5%)	0.1%	$78.79	-10.1%	Common Stock	22160N109
SAP	SAP SE-SPONSORED ADR	10,000 (+16.3%)	$2,429 (+5.7%)	0.2%	$233.04	—	ADR	803054204
CAT	CATERPILLAR INC	1,221 (+1.8%)	$699 (+22.2%)	0.1%	$427.63	+29.9%	Common Stock	149123101
FANG	DIAMONDBACK ENERGY INC	8,108 (+6.1%)	$1,219 (+11.5%)	0.1%	$162.25	-9.4%	Common Stock	25278X109
WMT	WALMART INC	11,433 (+2.1%)	$1,276 (+10.6%)	0.1%	$71.44	+50.1%	Common Stock	931142103
MCK	MCKESSON CORP	1,600 (+3.4%)	$1,314 (+9.7%)	0.1%	$622.38	+31.0%	Common Stock	58155Q103
LOW	LOWE'S COS INC	5,620 (+13.8%)	$1,355 (+9.2%)	0.1%	$212.96	+12.6%	Common Stock	548661107
EA	ELECTRONIC ARTS INC	7,078 (+7.2%)	$1,446 (+8.6%)	0.1%	$146.36	+37.8%	Common Stock	285512109
ORKA	ORUKA THERAPEUTICS INC	7,888 (+20.2%)	$239 (+89.4%)	0.0%	$24.86	+12.1%	Common Stock	687604108
ADSK	AUTODESK INC	10,199 (+3.6%)	$3,019 (-3.5%)	0.2%	$282.67	+7.0%	Common Stock	052769106
RAPP	RAPPORT THERAPEUTICS INC	10,766 (+45.5%)	$327 (+48.7%)	0.0%	$23.88	+15.9%	Common Stock	75383L102
XOM	EXXON MOBIL CORP	11,116 (+1.1%)	$1,338 (+7.9%)	0.1%	$107.01	+7.9%	Common Stock	30231G102
SNOW	SNOWFLAKE INC	6,100 (+10.9%)	$1,338 (+7.9%)	0.1%	$197.04	+23.9%	Common Stock	833445109
SVRA	SAVARA INC	33,155 (+9.4%)	$200 (+84.8%)	0.0%	$4.27	+14.7%	Common Stock	805111101
WFC	WELLS FARGO & CO	8,352 (+1.7%)	$778 (+13.0%)	0.1%	$58.17	+48.9%	Common Stock	949746101
CCEP	COCA-COLA EUROPACIFIC PARTNE	12,966 (+7.2%)	$1,176 (+7.5%)	0.1%	$76.67	+16.9%	Common Stock	G25839104
ARM	ARM HOLDINGS PLC-ADR	3,915 (+8.6%)	$428 (-16.1%)	0.0%	$130.05	—	ADR	042068205
TTWO	TAKE-TWO INTERACTIVE SOFTWRE	5,229 (+7.4%)	$1,339 (+6.4%)	0.1%	$186.07	+34.0%	Common Stock	874054109
CRM	SALESFORCE INC	2,482 (+1.8%)	$658 (+13.7%)	0.1%	$259.40	-4.3%	Common Stock	79466L302
CPRT	COPART INC	27,394 (+7.3%)	$1,072 (-6.6%)	0.1%	$51.93	-20.1%	Common Stock	217204106
ANNX	ANNEXON INC	36,084 (+2.3%)	$181 (+68.4%)	0.0%	$4.68	-18.3%	Common Stock	03589W102
JPM	JPMORGAN CHASE & CO	7,169 (+1.1%)	$2,310 (+3.3%)	0.2%	$207.32	+49.3%	Common Stock	46625H100
RTX	RTX CORP	3,490 (+2.4%)	$640 (+12.2%)	0.0%	$154.73	+12.0%	Common Stock	75513E101
PGEN	PRECIGEN INC	57,656 (+10.4%)	$241 (+40.3%)	0.0%	$1.50	+157.7%	Common Stock	74017N105
BRK/B	BERKSHIRE HATHAWAY INC-CL B	3,594 (+4.0%)	$1,807 (+3.9%)	0.1%	$440.75	+12.9%	Common Stock	084670702
GMAB	GENMAB A/S -SP ADR	9,525 (+29.6%)	$293 (+30.1%)	0.0%	$23.39	—	ADR	372303206
IMRX	IMMUNEERING CORP - CLASS A	15,522 (+210.4%)	$102 (+191.8%)	0.0%	$6.02	+6.6%	Common Stock	45254E107
ROP	ROPER TECHNOLOGIES INC	3,046 (+7.2%)	$1,356 (-4.3%)	0.1%	$537.42	-14.0%	Common Stock	776696106
PAYX	PAYCHEX INC	10,185 (+7.3%)	$1,143 (-5.1%)	0.1%	$129.44	-10.0%	Common Stock	704326107
MCHP	MICROCHIP TECHNOLOGY INC	15,294 (+7.3%)	$975 (+6.5%)	0.1%	$68.51	-10.4%	Common Stock	595017104
—	DEFINIUM THERAPEUTICS INC	16,052 (+20.4%)	$215 (+36.7%)	0.0%	$8.04	—	Common Stock	60255C885
SPOT	SPOTIFY TECHNOLOGY SA	2,200 (+25.7%)	$1,278 (+4.6%)	0.1%	$598.53	+4.4%	Common Stock	L8681T102
LXEO	LEXEO THERAPEUTICS INC	11,893 (+25.6%)	$118 (+87.9%)	0.0%	$7.42	+23.1%	Common Stock	52886X107
LYEL	LYELL IMMUNOPHARMA INC	3,457 (+2.7%)	$106 (+94.6%)	0.0%	$9.73	+130.1%	Common Stock	55083R203
TXN	TEXAS INSTRUMENTS INC	25,713 (+7.1%)	$4,461 (+1.2%)	0.3%	$182.45	-6.4%	Common Stock	882508104
IBM	INTL BUSINESS MACHINES CORP	2,429 (+2.4%)	$719 (+7.5%)	0.1%	$199.24	+50.0%	Common Stock	459200101
ESPR	ESPERION THERAPEUTICS INC	38,955 (+10.2%)	$144 (+53.9%)	0.0%	$2.42	+33.7%	Common Stock	29664W105
KO	COCA-COLA CO/THE	10,660 (+2.2%)	$745 (+7.0%)	0.1%	$62.51	+11.0%	Common Stock	191216100
PEPG	PEPGEN INC	11,202 (+94.9%)	$73 (+174.6%)	0.0%	$5.72	-9.3%	Common Stock	713317105
EXC	EXELON CORP	28,590 (+7.2%)	$1,246 (+3.8%)	0.1%	$38.73	+17.4%	Common Stock	30161N101
VRSK	VERISK ANALYTICS INC	3,944 (+6.9%)	$882 (-4.9%)	0.1%	$264.96	-15.0%	Common Stock	92345Y106
CTAS	CINTAS CORP	11,372 (+6.9%)	$2,139 (-2.1%)	0.2%	$195.23	-3.6%	Common Stock	172908105
UNH	UNITEDHEALTH GROUP INC	3,961 (+1.2%)	$1,308 (-3.3%)	0.1%	$465.61	-27.6%	Common Stock	91324P102
CRVS	CORVUS PHARMACEUTICALS INC	18,169 (+39.1%)	$140 (+45.3%)	0.0%	$7.12	+10.7%	Common Stock	221015100
CRSP	CRISPR THERAPEUTICS AG	20,529 (+28.8%)	$1,077 (+4.2%)	0.1%	$57.61	+4.0%	Common Stock	H17182108
INVA	INNOVIVA INC	12,184 (+10.3%)	$244 (+20.8%)	0.0%	$16.65	+17.3%	Common Stock	45781M101
ABSI	ABSCI CORP	34,503 (+31.6%)	$120 (+51.1%)	0.0%	$3.48	+4.6%	Common Stock	00091E109
SLN	SILENCE THERAPEUTICS PLC-ADR	13,653 (+65.9%)	$83 (+94.3%)	0.0%	$6.56	—	ADR	82686Q101
IOVA	IOVANCE BIOTHERAPEUTICS INC	64,686 (+2.0%)	$177 (+28.3%)	0.0%	$8.60	-73.1%	Common Stock	462260100
GE	GENERAL ELECTRIC	2,765 (+1.7%)	$853 (+4.1%)	0.1%	$175.20	+71.7%	Common Stock	369604301
TNGX	TANGO THERAPEUTICS INC	21,946 (+12.5%)	$194 (+18.7%)	0.0%	$8.87	-2.9%	Common Stock	87583X109
NXPI	NXP SEMICONDUCTORS NV	7,122 (+7.0%)	$1,552 (+2.0%)	0.1%	$222.36	-3.9%	Common Stock	N6596X109
AMN	AMN HEALTHCARE SERVICES INC	3,000 (+200.0%)	$47 (+144.2%)	0.0%	$18.41	-3.0%	Common Stock	001744101
MLYS	MINERALYS THERAPEUTICS INC	12,896 (+11.0%)	$468 (+6.2%)	0.0%	$14.51	+176.3%	Common Stock	603170101
ABT	ABBOTT LABORATORIES	4,538 (+2.3%)	$569 (-4.4%)	0.0%	$114.79	+10.9%	Common Stock	002824100
HON	HONEYWELL INTERNATIONAL INC	17,966 (+7.2%)	$3,505 (-0.7%)	0.3%	$193.88	+0.6%	Common Stock	438516106
RXRX	RECURSION PHARMACEUTICALS-A	83,787 (+11.9%)	$343 (-6.2%)	0.0%	$7.38	-32.9%	Common Stock	75629V104
OCS	OCULIS HOLDING AG	2,000 (+100.0%)	$40 (+127.2%)	0.0%	$18.86	+6.0%	Common Stock	H5870P102
XEL	XCEL ENERGY INC	16,740 (+7.2%)	$1,245 (-1.7%)	0.1%	$63.29	+23.7%	Common Stock	98389B100
SRZN	SURROZEN INC	1,500 (+50.0%)	$34 (+163.1%)	0.0%	$12.38	+30.6%	Common Stock	86889P208
CMCSA	COMCAST CORP-CLASS A	102,850 (+5.8%)	$3,074 (+0.6%)	0.2%	$36.78	-22.4%	Common Stock	20030N101
HUMA	HUMACYTE INC	30,516 (+9.9%)	$29 (-39.3%)	0.0%	$3.81	-62.8%	Common Stock	44486Q103
BNTX	BIONTECH SE-ADR	18,075 (+2.5%)	$1,721 (-1.1%)	0.1%	$110.83	—	ADR	09075V102
PM	PHILIP MORRIS INTERNATIONAL	4,058 (+2.2%)	$656 (+1.9%)	0.1%	$116.24	+32.1%	Common Stock	718172109
DIS	WALT DISNEY CO/THE	4,688 (+2.2%)	$537 (+2.2%)	0.0%	$105.71	+3.6%	Common Stock	254687106
CCRN	CROSS COUNTRY HEALTHCARE INC	3,000 (+200.0%)	$24 (+71.1%)	0.0%	$11.69	-6.5%	Common Stock	227483104
OABI	OMNIAB INC	23,457 (+9.1%)	$43 (+26.1%)	0.0%	$4.49	-61.3%	Common Stock	68218J103
AMLX	AMYLYX PHARMACEUTICALS INC	17,895 (+14.5%)	$216 (+1.8%)	0.0%	$9.54	+42.4%	Common Stock	03237H101
BKR	BAKER HUGHES CO	27,924 (+7.3%)	$1,272 (+0.3%)	0.1%	$38.87	+21.8%	Common Stock	05722G100
ALT	ALTIMMUNE INC	17,003 (+9.9%)	$61 (+5.2%)	0.0%	$7.21	-39.6%	Common Stock	02155H200
XLY	SS CONSUMER DISC SELECT SECT	6,030 (+100.0%)	$720 (-0.3%)	0.1%	$158.76	—	ETP	81369Y407
CCCC	C4 THERAPEUTICS INC	15,792 (+26.6%)	$30 (+8.9%)	0.0%	$4.43	-46.5%	Common Stock	12529R107
WDAY	WORKDAY INC-CLASS A	11,178 (+12.0%)	$2,401 (-0.1%)	0.2%	$256.90	-11.6%	Common Stock	98138H101
KHC	KRAFT HEINZ CO/THE	33,496 (+7.2%)	$812 (-0.2%)	0.1%	$29.67	-17.0%	Common Stock	500754106
FDMT	4D MOLECULAR THERAPEUTICS IN	9,310 (+13.7%)	$70 (-1.8%)	0.0%	$17.28	-41.3%	Common Stock	35104E100

Exited Positions (47)

RCL ROYAL CARIBBEAN CRUISES LTD 0.2%

Value ($000) $2,721 Shares 8,399 Est. Cost $119.20 Unrealized +136.2%

RBLX ROBLOX CORP -CLASS A 0.2%

Value ($000) $2,286 Shares 16,500 Est. Cost $78.55 Unrealized +35.2%

— VERONA PHARMA PLC - ADR 0.1%

Value ($000) $1,583 Shares 14,838 Est. Cost $22.68 Unrealized —

— MERUS NV 0.1%

Value ($000) $1,248 Shares 13,258 Est. Cost $40.52 Unrealized —

ANET ARISTA NETWORKS INC 0.1%

Value ($000) $801 Shares 5,500 Est. Cost $128.77 Unrealized +6.9%

DUOL DUOLINGO 0.1%

Value ($000) $785 Shares 2,439 Est. Cost $338.32 Unrealized -30.4%

TJX TJX COMPANIES INC 0.1%

Value ($000) $718 Shares 4,970 Est. Cost $109.25 Unrealized +35.2%

— AKERO THERAPEUTICS INC 0.1%

Value ($000) $666 Shares 14,021 Est. Cost $28.62 Unrealized —

TTD TRADE DESK INC/THE -CLASS A 0.0%

Value ($000) $577 Shares 11,765 Est. Cost $100.77 Unrealized -56.0%

CDW CDW CORP/DE 0.0%

Value ($000) $551 Shares 3,460 Est. Cost $197.38 Unrealized -25.5%

LULU LULULEMON ATHLETICA INC 0.0%

Value ($000) $539 Shares 3,029 Est. Cost $313.63 Unrealized -42.2%

GFS GLOBALFOUNDRIES INC 0.0%

Value ($000) $525 Shares 14,651 Est. Cost $44.40 Unrealized -19.9%

T AT&T INC 0.0%

Value ($000) $518 Shares 18,356 Est. Cost $26.96 Unrealized -6.2%

VZ VERIZON COMMUNICATIONS INC 0.0%

Value ($000) $473 Shares 10,756 Est. Cost $38.08 Unrealized +6.3%

— 89BIO INC 0.0%

Value ($000) $382 Shares 25,996 Est. Cost $9.15 Unrealized —

— AVADEL PHARMACEUTICALS 0.0%

Value ($000) $260 Shares 17,020 Est. Cost $13.39 Unrealized —

GSK GSK PLC-SPON ADR 0.0%

Value ($000) $259 Shares 6,000 Est. Cost $42.86 Unrealized —

— TOURMALINE BIO INC 0.0%

Value ($000) $215 Shares 4,503 Est. Cost $24.52 Unrealized —

— CUREVAC NV 0.0%

Value ($000) $213 Shares 39,466 Est. Cost $3.65 Unrealized —

RZLT REZOLUTE INC 0.0%

Value ($000) $94 Shares 10,000 Est. Cost $6.66 Unrealized +17.7%

LXRX LEXICON PHARMACEUTICALS INC 0.0%

Value ($000) $86 Shares 63,698 Est. Cost $1.68 Unrealized -18.1%

HCM HUTCHMED CHINA-ADR 0.0%

Value ($000) $86 Shares 5,437 Est. Cost $17.60 Unrealized —

— ASTRIA THERAPEUTICS INC 0.0%

Value ($000) $72 Shares 9,892 Est. Cost $8.94 Unrealized —

BBOT BRIDGEBIO ONCOLOGY THERAPEUT 0.0%

Value ($000) $58 Shares 5,000 Est. Cost $11.58 Unrealized —

AMRN AMARIN CORP PLC -ADR 0.0%

Value ($000) $58 Shares 3,534 Est. Cost $16.22 Unrealized —

— SCPHARMACEUTICALS INC 0.0%

Value ($000) $53 Shares 9,342 Est. Cost $3.55 Unrealized —

ALEC ALECTOR INC 0.0%

Value ($000) $53 Shares 17,741 Est. Cost $5.77 Unrealized -69.3%

RNAC CARTESIAN THERAPEUTICS INC 0.0%

Value ($000) $47 Shares 4,558 Est. Cost $20.04 Unrealized -59.6%

TVRD TVARDI THERAPEUTICS INC 0.0%

Value ($000) $39 Shares 1,000 Est. Cost $28.47 Unrealized -68.5%

MXCT MAXCYTE INC 0.0%

Value ($000) $30 Shares 18,687 Est. Cost $4.23 Unrealized -62.3%

TVGN TEVOGEN BIO HOLDINGS INC 0.0%

Value ($000) $27 Shares 34,479 Est. Cost $1.30 Unrealized -59.9%

BNR BURNING ROCK BIOTECH LTD-ADR 0.0%

Value ($000) $26 Shares 3,000 Est. Cost $8.65 Unrealized —

NKTX NKARTA INC 0.0%

Value ($000) $26 Shares 12,450 Est. Cost $3.09 Unrealized -35.2%

FATE FATE THERAPEUTICS INC 0.0%

Value ($000) $25 Shares 20,216 Est. Cost $2.52 Unrealized -52.4%

CLYM CLIMB BIO INC 0.0%

Value ($000) $24 Shares 11,878 Est. Cost $3.62 Unrealized -33.6%

BMEA BIOMEA FUSION INC 0.0%

Value ($000) $21 Shares 10,431 Est. Cost $8.21 Unrealized -82.9%

MGNX MACROGENICS INC 0.0%

Value ($000) $19 Shares 11,079 Est. Cost $7.18 Unrealized -78.1%

TCRX TSCAN THERAPEUTICS INC 0.0%

Value ($000) $17 Shares 9,197 Est. Cost $4.34 Unrealized -66.6%

PLRX PLIANT THERAPEUTICS INC 0.0%

Value ($000) $16 Shares 10,760 Est. Cost $14.60 Unrealized -89.7%

— APPLIED THERAPEUTICS INC 0.0%

Value ($000) $15 Shares 25,243 Est. Cost $0.76 Unrealized —

— SUTRO BIOPHARMA INC 0.0%

Value ($000) $13 Shares 14,860 Est. Cost $1.81 Unrealized —

ARTV ARTIVA BIOTHERAPEUTICS INC 0.0%

Value ($000) $12 Shares 4,281 Est. Cost $12.01 Unrealized -68.6%

ACRV ACRIVON THERAPEUTICS INC 0.0%

Value ($000) $10 Shares 5,514 Est. Cost $7.27 Unrealized -70.1%

— MERSANA THERAPEUTICS INC 0.0%

Value ($000) $7 Shares 875 Est. Cost $7.76 Unrealized —

OKUR ONKURE THERAPEUTICS INC-A 0.0%

Value ($000) $6 Shares 2,251 Est. Cost $14.95 Unrealized -80.0%

QTTB Q32 BIO INC 0.0%

Value ($000) $4 Shares 2,138 Est. Cost $31.58 Unrealized -91.0%

WOLF WOLFSPEED INC 0.0%

Value ($000) $2 Shares 83 Est. Cost $25.35 Unrealized -9.5%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
RCL	ROYAL CARIBBEAN CRUISES LTD	8,399	$2,721	0.2%	$119.20	+136.2%	—	V7780T103
RBLX	ROBLOX CORP -CLASS A	16,500	$2,286	0.2%	$78.55	+35.2%	—	771049103
—	VERONA PHARMA PLC - ADR	14,838	$1,583	0.1%	$22.68	—	—	925050106
—	MERUS NV	13,258	$1,248	0.1%	$40.52	—	—	N5749R100
ANET	ARISTA NETWORKS INC	5,500	$801	0.1%	$128.77	+6.9%	—	040413205
DUOL	DUOLINGO	2,439	$785	0.1%	$338.32	-30.4%	—	26603R106
TJX	TJX COMPANIES INC	4,970	$718	0.1%	$109.25	+35.2%	—	872540109
—	AKERO THERAPEUTICS INC	14,021	$666	0.1%	$28.62	—	—	00973Y108
TTD	TRADE DESK INC/THE -CLASS A	11,765	$577	0.0%	$100.77	-56.0%	—	88339J105
CDW	CDW CORP/DE	3,460	$551	0.0%	$197.38	-25.5%	—	12514G108
LULU	LULULEMON ATHLETICA INC	3,029	$539	0.0%	$313.63	-42.2%	—	550021109
GFS	GLOBALFOUNDRIES INC	14,651	$525	0.0%	$44.40	-19.9%	—	G39387108
T	AT&T INC	18,356	$518	0.0%	$26.96	-6.2%	—	00206R102
VZ	VERIZON COMMUNICATIONS INC	10,756	$473	0.0%	$38.08	+6.3%	—	92343V104
—	89BIO INC	25,996	$382	0.0%	$9.15	—	—	282559103
—	AVADEL PHARMACEUTICALS	17,020	$260	0.0%	$13.39	—	—	G29687103
GSK	GSK PLC-SPON ADR	6,000	$259	0.0%	$42.86	—	—	37733W204
—	TOURMALINE BIO INC	4,503	$215	0.0%	$24.52	—	—	89157D105
—	CUREVAC NV	39,466	$213	0.0%	$3.65	—	—	N2451R105
RZLT	REZOLUTE INC	10,000	$94	0.0%	$6.66	+17.7%	—	76200L309
LXRX	LEXICON PHARMACEUTICALS INC	63,698	$86	0.0%	$1.68	-18.1%	—	528872302
HCM	HUTCHMED CHINA-ADR	5,437	$86	0.0%	$17.60	—	—	44842L103
—	ASTRIA THERAPEUTICS INC	9,892	$72	0.0%	$8.94	—	—	04635X102
BBOT	BRIDGEBIO ONCOLOGY THERAPEUT	5,000	$58	0.0%	$11.58	—	—	107924102
AMRN	AMARIN CORP PLC -ADR	3,534	$58	0.0%	$16.22	—	—	023111404
—	SCPHARMACEUTICALS INC	9,342	$53	0.0%	$3.55	—	—	810648105
ALEC	ALECTOR INC	17,741	$53	0.0%	$5.77	-69.3%	—	014442107
RNAC	CARTESIAN THERAPEUTICS INC	4,558	$47	0.0%	$20.04	-59.6%	—	816212302
TVRD	TVARDI THERAPEUTICS INC	1,000	$39	0.0%	$28.47	-68.5%	—	140755307
MXCT	MAXCYTE INC	18,687	$30	0.0%	$4.23	-62.3%	—	57777K106
TVGN	TEVOGEN BIO HOLDINGS INC	34,479	$27	0.0%	$1.30	-59.9%	—	88165K101
BNR	BURNING ROCK BIOTECH LTD-ADR	3,000	$26	0.0%	$8.65	—	—	12233L206
NKTX	NKARTA INC	12,450	$26	0.0%	$3.09	-35.2%	—	65487U108
FATE	FATE THERAPEUTICS INC	20,216	$25	0.0%	$2.52	-52.4%	—	31189P102
CLYM	CLIMB BIO INC	11,878	$24	0.0%	$3.62	-33.6%	—	28658R106
BMEA	BIOMEA FUSION INC	10,431	$21	0.0%	$8.21	-82.9%	—	09077A106
MGNX	MACROGENICS INC	11,079	$19	0.0%	$7.18	-78.1%	—	556099109
TCRX	TSCAN THERAPEUTICS INC	9,197	$17	0.0%	$4.34	-66.6%	—	89854M101
PLRX	PLIANT THERAPEUTICS INC	10,760	$16	0.0%	$14.60	-89.7%	—	729139105
—	APPLIED THERAPEUTICS INC	25,243	$15	0.0%	$0.76	—	—	03828A101
—	SUTRO BIOPHARMA INC	14,860	$13	0.0%	$1.81	—	—	869367102
ARTV	ARTIVA BIOTHERAPEUTICS INC	4,281	$12	0.0%	$12.01	-68.6%	—	04317A107
ACRV	ACRIVON THERAPEUTICS INC	5,514	$10	0.0%	$7.27	-70.1%	—	004890109
—	MERSANA THERAPEUTICS INC	875	$7	0.0%	$7.76	—	—	59045L205
OKUR	ONKURE THERAPEUTICS INC-A	2,251	$6	0.0%	$14.95	-80.0%	—	68277Q105
QTTB	Q32 BIO INC	2,138	$4	0.0%	$31.58	-91.0%	—	746964105
WOLF	WOLFSPEED INC	83	$2	0.0%	$25.35	-9.5%	—	97785W106

Decreased Positions (211)

AVGO BROADCOM INC 3.1%

Value ($000) $39,866 (-18.0%) Shares 115,185 (-21.8%) Est. Cost $170.46 Unrealized +109.4%

SLV ISHARES SILVER TRUST 0.1%

Value ($000) $1,482 (-80.3%) Shares 23,000 (-87.1%) Est. Cost $38.34 Unrealized —

MSFT MICROSOFT CORP 5.4%

Value ($000) $69,863 (-7.7%) Shares 144,458 (-1.1%) Est. Cost $373.17 Unrealized +34.1%

AMZN AMAZON.COM INC 3.8%

Value ($000) $49,413 (-7.7%) Shares 214,076 (-12.2%) Est. Cost $159.54 Unrealized +43.4%

ORCL ORACLE CORP 0.1%

Value ($000) $1,824 (-69.0%) Shares 9,360 (-55.3%) Est. Cost $154.36 Unrealized +54.2%

REGN REGENERON PHARMACEUTICALS 1.2%

Value ($000) $15,247 (+27.0%) Shares 19,753 (-7.5%) Est. Cost $888.90 Unrealized -23.7%

BABA ALIBABA GROUP HOLDING-SP ADR 0.3%

Value ($000) $3,266 (-40.9%) Shares 22,282 (-27.9%) Est. Cost $178.73 Unrealized —

BSX BOSTON SCIENTIFIC CORP 0.1%

Value ($000) $954 (-69.5%) Shares 10,000 (-68.8%) Est. Cost $96.10 Unrealized +2.0%

APP APPLOVIN CORP-CLASS A 1.0%

Value ($000) $12,671 (-14.5%) Shares 18,805 (-8.8%) Est. Cost $148.31 Unrealized +324.9%

BTI BRITISH AMERICAN TOB-SP ADR 0.3%

Value ($000) $3,538 (-37.7%) Shares 61,857 (-42.2%) Est. Cost $49.37 Unrealized —

AAPL APPLE INC 5.1%

Value ($000) $66,053 (+3.1%) Shares 242,967 (-3.4%) Est. Cost $210.12 Unrealized +27.7%

COST COSTCO WHOLESALE CORP 1.0%

Value ($000) $12,865 (-12.1%) Shares 14,919 (-5.7%) Est. Cost $753.38 Unrealized +20.2%

SE SEA LTD-ADR 0.2%

Value ($000) $2,692 (-38.3%) Shares 21,100 (-13.5%) Est. Cost $102.56 Unrealized —

YMM FULL TRUCK ALLIANCE -SPN ADR 0.2%

Value ($000) $2,007 (-42.1%) Shares 187,000 (-30.0%) Est. Cost $7.86 Unrealized —

MRK MERCK & CO. INC. 0.1%

Value ($000) $1,223 (-54.0%) Shares 11,512 (-63.3%) Est. Cost $86.78 Unrealized +7.4%

ALAB ASTERA LABS INC 0.1%

Value ($000) $699 (-65.0%) Shares 4,200 (-58.8%) Est. Cost $84.39 Unrealized +98.2%

FTNT FORTINET INC 0.1%

Value ($000) $1,671 (-36.4%) Shares 21,044 (-32.6%) Est. Cost $86.26 Unrealized -3.9%

ABBV ABBVIE INC 0.1%

Value ($000) $1,624 (-35.7%) Shares 7,106 (-34.8%) Est. Cost $175.92 Unrealized +29.3%

FUTU FUTU HOLDINGS LTD-ADR 0.2%

Value ($000) $2,585 (-24.8%) Shares 15,740 (-20.4%) Est. Cost $173.91 Unrealized —

THC TENET HEALTHCARE CORP 0.1%

Value ($000) $1,590 (-34.8%) Shares 8,000 (-33.3%) Est. Cost $150.35 Unrealized +34.4%

AS AMER SPORTS INC 0.0%

Value ($000) $431 (-65.9%) Shares 11,537 (-68.2%) Est. Cost $15.70 Unrealized +118.6%

GH GUARDANT HEALTH INC 0.2%

Value ($000) $2,153 (+57.7%) Shares 21,081 (-3.6%) Est. Cost $28.53 Unrealized +213.6%

TEM TEMPUS AI INC 0.1%

Value ($000) $1,663 (-30.3%) Shares 28,168 (-4.7%) Est. Cost $49.61 Unrealized +57.7%

RVMD REVOLUTION MEDICINES INC 0.2%

Value ($000) $2,708 (+35.6%) Shares 34,001 (-20.5%) Est. Cost $41.25 Unrealized +59.0%

UBER UBER TECHNOLOGIES INC 0.2%

Value ($000) $2,971 (-18.6%) Shares 36,365 (-2.4%) Est. Cost $45.99 Unrealized +95.8%

TME TENCENT MUSIC ENTERTAINM-ADR 0.1%

Value ($000) $1,615 (-29.4%) Shares 92,100 (-6.0%) Est. Cost $20.00 Unrealized —

BBIO BRIDGEBIO PHARMA INC 0.2%

Value ($000) $2,402 (+38.0%) Shares 31,402 (-6.3%) Est. Cost $28.45 Unrealized +130.7%

ADBE ADOBE INC 0.3%

Value ($000) $4,146 (-13.6%) Shares 11,846 (-12.9%) Est. Cost $514.67 Unrealized -33.9%

LI LI AUTO INC - ADR 0.0%

Value ($000) $169 (-77.7%) Shares 10,000 (-66.7%) Est. Cost $24.02 Unrealized —

SMMT SUMMIT THERAPEUTICS INC 0.2%

Value ($000) $2,122 (-21.1%) Shares 121,307 (-6.8%) Est. Cost $8.69 Unrealized +116.5%

SNY SANOFI-ADR 0.2%

Value ($000) $2,671 (-17.5%) Shares 55,120 (-19.7%) Est. Cost $52.01 Unrealized —

ARWR ARROWHEAD PHARMACEUTICALS IN 0.2%

Value ($000) $2,000 (+37.3%) Shares 30,130 (-28.7%) Est. Cost $24.64 Unrealized +98.9%

CLS CELESTICA INC 0.3%

Value ($000) $3,580 (+17.2%) Shares 12,110 (-2.3%) Est. Cost $96.91 Unrealized +211.0%

ON ON SEMICONDUCTOR 0.0%

Value ($000) $135 (-79.4%) Shares 2,500 (-81.2%) Est. Cost $60.19 Unrealized -14.8%

RERE ATRENEW INC 0.2%

Value ($000) $1,957 (-20.6%) Shares 369,300 (-31.1%) Est. Cost $4.60 Unrealized —

NTLA INTELLIA THERAPEUTICS INC 0.0%

Value ($000) $170 (-74.7%) Shares 18,874 (-51.4%) Est. Cost $19.97 Unrealized -31.1%

UTHR UNITED THERAPEUTICS CORP 0.3%

Value ($000) $3,662 (-12.0%) Shares 7,516 (-24.3%) Est. Cost $285.40 Unrealized +63.2%

CVS CVS HEALTH CORP 0.1%

Value ($000) $1,270 (-27.7%) Shares 16,000 (-31.3%) Est. Cost $57.99 Unrealized +35.7%

TERN TERNS PHARMACEUTICALS INC 0.0%

Value ($000) $601 (+421.8%) Shares 14,878 (-3.0%) Est. Cost $6.80 Unrealized +240.0%

ONC BEONE MEDICINES LTD-ADR 0.1%

Value ($000) $1,558 (-22.4%) Shares 5,129 (-12.9%) Est. Cost $191.08 Unrealized —

MCD MCDONALD'S CORP 0.0%

Value ($000) $569 (-44.0%) Shares 1,861 (-44.3%) Est. Cost $273.71 Unrealized +11.5%

AXSM AXSOME THERAPEUTICS INC 0.1%

Value ($000) $1,500 (+41.2%) Shares 8,215 (-6.1%) Est. Cost $80.54 Unrealized +73.4%

XBI SS SPDR S&P BIOTECH ETF 0.0%

Value ($000) $74 (-85.0%) Shares 608 (-87.6%) Est. Cost $99.34 Unrealized —

APH AMPHENOL CORP-CL A 0.5%

Value ($000) $6,362 (+7.0%) Shares 47,000 (-2.1%) Est. Cost $61.93 Unrealized +115.6%

MNDY MONDAY.COM LTD 0.1%

Value ($000) $664 (-37.7%) Shares 4,500 (-18.2%) Est. Cost $266.37 Unrealized -36.8%

PG PROCTER & GAMBLE CO/THE 0.1%

Value ($000) $981 (-29.0%) Shares 6,843 (-23.8%) Est. Cost $154.07 Unrealized -4.5%

MDGL MADRIGAL PHARMACEUTICALS INC 0.2%

Value ($000) $2,155 (+20.3%) Shares 3,701 (-5.3%) Est. Cost $226.42 Unrealized +125.6%

INCY INCYTE CORP 0.3%

Value ($000) $3,259 (+12.2%) Shares 32,991 (-3.6%) Est. Cost $61.79 Unrealized +56.6%

CRDO CREDO TECHNOLOGY GROUP HOLDI 0.1%

Value ($000) $1,511 (-18.9%) Shares 10,500 (-18.0%) Est. Cost $58.32 Unrealized +163.7%

VTRS VIATRIS INC 0.2%

Value ($000) $2,337 (+15.5%) Shares 187,680 (-8.2%) Est. Cost $10.25 Unrealized +4.6%

LENZ LENZ THERAPEUTICS INC 0.0%

Value ($000) $82 (-78.1%) Shares 5,099 (-36.3%) Est. Cost $32.27 Unrealized -9.7%

FOLD AMICUS THERAPEUTICS INC 0.1%

Value ($000) $716 (+68.2%) Shares 50,275 (-6.9%) Est. Cost $11.47 Unrealized -14.4%

BLTE BELITE BIO INC - ADR 0.0%

Value ($000) $80 (-78.4%) Shares 500 (-90.0%) Est. Cost $74.00 Unrealized —

JAZZ JAZZ PHARMACEUTICALS PLC 0.1%

Value ($000) $1,683 (+20.1%) Shares 9,902 (-6.9%) Est. Cost $119.64 Unrealized +28.1%

OCUL OCULAR THERAPEUTIX INC 0.0%

Value ($000) $434 (-38.7%) Shares 35,716 (-41.0%) Est. Cost $7.34 Unrealized +65.5%

KRYS KRYSTAL BIOTECH INC 0.1%

Value ($000) $1,165 (+30.1%) Shares 4,725 (-6.9%) Est. Cost $151.69 Unrealized +38.8%

ELV ELEVANCE HEALTH INC 0.1%

Value ($000) $701 (-27.7%) Shares 2,000 (-33.3%) Est. Cost $405.10 Unrealized -16.9%

IRTC IRHYTHM HOLDINGS INC 0.0%

Value ($000) $35 (-87.1%) Shares 200 (-87.5%) Est. Cost $158.94 Unrealized +11.5%

IMVT IMMUNOVANT INC 0.1%

Value ($000) $726 (+47.4%) Shares 28,561 (-6.5%) Est. Cost $30.99 Unrealized -28.0%

DEO DIAGEO PLC-SPONSORED ADR 0.0%

Value ($000) $163 (-58.6%) Shares 1,884 (-54.2%) Est. Cost $146.67 Unrealized —

HALO HALOZYME THERAPEUTICS INC 0.1%

Value ($000) $1,290 (-14.2%) Shares 19,162 (-6.5%) Est. Cost $45.54 Unrealized +47.7%

BHVN BIOHAVEN LTD 0.0%

Value ($000) $90 (-69.9%) Shares 8,000 (-60.0%) Est. Cost $17.82 Unrealized -30.5%

TTMI TTM TECHNOLOGIES 0.1%

Value ($000) $1,587 (+14.8%) Shares 23,000 (-4.2%) Est. Cost $46.47 Unrealized +40.4%

TVTX TRAVERE THERAPEUTICS INC 0.0%

Value ($000) $576 (+54.3%) Shares 15,079 (-3.5%) Est. Cost $11.26 Unrealized +188.8%

— INDIVIOR PLC 0.1%

Value ($000) $730 (+38.4%) Shares 20,345 (-7.0%) Est. Cost $12.43 Unrealized —

VERA VERA THERAPEUTICS INC 0.0%

Value ($000) $528 (+62.3%) Shares 10,417 (-6.9%) Est. Cost $32.62 Unrealized +8.9%

ORIC ORIC PHARMACEUTICALS INC 0.0%

Value ($000) $130 (-60.0%) Shares 15,870 (-41.3%) Est. Cost $10.07 Unrealized +14.3%

OMER OMEROS CORP 0.0%

Value ($000) $284 (+216.2%) Shares 16,553 (-24.5%) Est. Cost $5.51 Unrealized +56.3%

RMBS RAMBUS INC 0.0%

Value ($000) $643 (-22.8%) Shares 7,000 (-12.5%) Est. Cost $77.09 Unrealized +27.7%

ALVO ALVOTECH SA 0.0%

Value ($000) $262 (-41.8%) Shares 51,006 (-7.0%) Est. Cost $12.21 Unrealized -48.3%

ACLX ARCELLX INC 0.0%

Value ($000) $614 (-23.0%) Shares 9,422 (-3.1%) Est. Cost $60.22 Unrealized +32.5%

ARQT ARCUTIS BIOTHERAPEUTICS INC 0.0%

Value ($000) $580 (+46.3%) Shares 19,960 (-5.0%) Est. Cost $7.68 Unrealized +233.5%

LEGN LEGEND BIOTECH CORP-ADR 0.0%

Value ($000) $298 (-38.0%) Shares 13,720 (-7.0%) Est. Cost $52.47 Unrealized —

ZLAB ZAI LAB LTD-ADR 0.0%

Value ($000) $113 (-60.4%) Shares 6,380 (-23.9%) Est. Cost $25.38 Unrealized —

BEAM BEAM THERAPEUTICS INC 0.0%

Value ($000) $458 (-26.6%) Shares 16,535 (-35.7%) Est. Cost $24.88 Unrealized +2.6%

PCVX VAXCYTE INC 0.1%

Value ($000) $984 (+20.1%) Shares 21,331 (-6.3%) Est. Cost $63.74 Unrealized -29.8%

GRAL GRAIL INC 0.1%

Value ($000) $681 (+30.5%) Shares 7,952 (-9.8%) Est. Cost $20.88 Unrealized +313.8%

AGIO AGIOS PHARMACEUTICALS INC 0.0%

Value ($000) $259 (-36.7%) Shares 9,502 (-6.7%) Est. Cost $34.10 Unrealized +2.9%

PTGX PROTAGONIST THERAPEUTICS INC 0.1%

Value ($000) $1,204 (+14.0%) Shares 13,787 (-13.3%) Est. Cost $34.08 Unrealized +140.2%

PTCT PTC THERAPEUTICS INC 0.1%

Value ($000) $1,001 (+17.2%) Shares 13,183 (-5.3%) Est. Cost $31.09 Unrealized +133.7%

RARE ULTRAGENYX PHARMACEUTICAL IN 0.0%

Value ($000) $362 (-28.8%) Shares 15,721 (-6.9%) Est. Cost $46.48 Unrealized -29.3%

DYN DYNE THERAPEUTICS INC 0.0%

Value ($000) $455 (+44.3%) Shares 23,273 (-6.7%) Est. Cost $24.70 Unrealized -23.3%

NBIX NEUROCRINE BIOSCIENCES INC 0.2%

Value ($000) $2,304 (-5.6%) Shares 16,247 (-6.5%) Est. Cost $127.72 Unrealized +13.4%

EWTX EDGEWISE THERAPEUTICS INC 0.0%

Value ($000) $428 (+42.9%) Shares 17,251 (-6.6%) Est. Cost $16.74 Unrealized +19.9%

PRCT PROCEPT BIOROBOTICS CORP 0.0%

Value ($000) $157 (-44.9%) Shares 5,000 (-37.5%) Est. Cost $56.54 Unrealized -41.3%

TARS TARSUS PHARMACEUTICALS INC 0.0%

Value ($000) $566 (+28.8%) Shares 6,917 (-6.5%) Est. Cost $28.09 Unrealized +165.8%

FTRE FORTREA HOLDINGS INC 0.0%

Value ($000) $260 (+93.8%) Shares 15,057 (-5.4%) Est. Cost $27.70 Unrealized -55.4%

JANX JANUX THERAPEUTICS INC 0.0%

Value ($000) $135 (-47.5%) Shares 9,801 (-7.0%) Est. Cost $29.16 Unrealized -19.3%

MRNA MODERNA INC 0.1%

Value ($000) $1,877 (+6.6%) Shares 63,661 (-6.7%) Est. Cost $94.45 Unrealized -71.2%

ALKS ALKERMES PLC 0.1%

Value ($000) $753 (-13.3%) Shares 26,906 (-7.0%) Est. Cost $27.16 Unrealized +10.3%

ARCT ARCTURUS THERAPEUTICS HOLDIN 0.0%

Value ($000) $28 (-80.2%) Shares 4,630 (-40.3%) Est. Cost $22.36 Unrealized -51.7%

CYTK CYTOKINETICS INC 0.1%

Value ($000) $1,266 (+9.8%) Shares 19,923 (-5.0%) Est. Cost $54.55 Unrealized +14.0%

GMED GLOBUS MEDICAL INC - A 0.0%

Value ($000) $175 (-39.0%) Shares 2,000 (-60.0%) Est. Cost $57.58 Unrealized +31.8%

WVE WAVE LIFE SCIENCES LTD 0.1%

Value ($000) $676 (+18.5%) Shares 39,742 (-49.0%) Est. Cost $8.43 Unrealized +20.6%

ACAD ACADIA PHARMACEUTICALS INC 0.1%

Value ($000) $736 (+16.7%) Shares 27,568 (-6.8%) Est. Cost $20.65 Unrealized +15.7%

INBX INHIBRX BIOSCIENCES INC 0.0%

Value ($000) $187 (+118.9%) Shares 2,370 (-6.7%) Est. Cost $15.23 Unrealized +347.3%

TYRA TYRA BIOSCIENCES INC 0.0%

Value ($000) $229 (+74.9%) Shares 8,697 (-6.9%) Est. Cost $17.72 Unrealized +3.7%

HTHT H WORLD GROUP LTD-ADR 0.0%

Value ($000) $301 (-24.5%) Shares 6,398 (-37.3%) Est. Cost $37.04 Unrealized —

ABCL ABCELLERA BIOLOGICS INC 0.0%

Value ($000) $167 (-36.7%) Shares 48,777 (-6.9%) Est. Cost $4.17 Unrealized +6.9%

ZYME ZYMEWORKS INC 0.0%

Value ($000) $321 (+42.7%) Shares 12,195 (-7.4%) Est. Cost $10.16 Unrealized +114.7%

AMRX AMNEAL PHARMACEUTICALS INC 0.0%

Value ($000) $645 (+17.1%) Shares 51,225 (-7.0%) Est. Cost $8.38 Unrealized +36.6%

ADMA ADMA BIOLOGICS INC 0.1%

Value ($000) $707 (+15.4%) Shares 38,782 (-7.3%) Est. Cost $9.93 Unrealized +69.7%

— DYNAVAX TECHNOLOGIES CORP 0.0%

Value ($000) $294 (+44.2%) Shares 19,134 (-6.9%) Est. Cost $12.51 Unrealized —

IBRX IMMUNITYBIO INC 0.0%

Value ($000) $318 (-22.0%) Shares 160,500 (-3.1%) Est. Cost $3.83 Unrealized -40.8%

TSHA TAYSHA GENE THERAPIES INC 0.0%

Value ($000) $245 (+57.0%) Shares 44,635 (-6.7%) Est. Cost $2.12 Unrealized +129.6%

AUPH AURINIA PHARMACEUTICALS INC 0.0%

Value ($000) $343 (+34.4%) Shares 21,483 (-6.9%) Est. Cost $7.25 Unrealized +95.4%

ALMS ALUMIS INC 0.0%

Value ($000) $155 (+128.2%) Shares 15,840 (-6.7%) Est. Cost $7.34 Unrealized -4.9%

AVXL ANAVEX LIFE SCIENCES CORP 0.0%

Value ($000) $52 (-61.3%) Shares 14,559 (-3.3%) Est. Cost $6.46 Unrealized -5.1%

RLAY RELAY THERAPEUTICS INC 0.0%

Value ($000) $239 (+51.5%) Shares 28,243 (-6.5%) Est. Cost $7.93 Unrealized -10.0%

RGEN REPLIGEN CORP 0.0%

Value ($000) $590 (-11.7%) Shares 3,600 (-28.0%) Est. Cost $123.66 Unrealized +26.7%

IDYA IDEAYA BIOSCIENCES INC 0.0%

Value ($000) $494 (+18.1%) Shares 14,285 (-7.0%) Est. Cost $35.50 Unrealized -10.2%

TXG 10X GENOMICS INC-CLASS A 0.0%

Value ($000) $310 (+32.0%) Shares 18,979 (-5.4%) Est. Cost $15.60 Unrealized -3.2%

HRMY HARMONY BIOSCIENCES HOLDINGS 0.0%

Value ($000) $351 (+26.4%) Shares 9,385 (-6.9%) Est. Cost $33.01 Unrealized -0.4%

CSTL CASTLE BIOSCIENCES INC 0.0%

Value ($000) $185 (+59.8%) Shares 4,756 (-6.5%) Est. Cost $22.88 Unrealized +40.9%

NVAX NOVAVAX INC 0.0%

Value ($000) $178 (-27.9%) Shares 26,479 (-7.0%) Est. Cost $9.67 Unrealized -22.0%

VCYT VERACYTE INC 0.0%

Value ($000) $542 (+14.5%) Shares 12,881 (-6.6%) Est. Cost $27.00 Unrealized +49.3%

PRME PRIME MEDICINE INC 0.0%

Value ($000) $102 (-39.9%) Shares 29,414 (-4.0%) Est. Cost $5.70 Unrealized -22.0%

REPL REPLIMUNE GROUP INC 0.0%

Value ($000) $124 (+116.7%) Shares 12,782 (-6.6%) Est. Cost $11.04 Unrealized -23.0%

TRVI TREVI THERAPEUTICS INC 0.0%

Value ($000) $262 (+33.9%) Shares 20,895 (-2.1%) Est. Cost $3.86 Unrealized +199.5%

SNDX SYNDAX PHARMACEUTICALS INC 0.0%

Value ($000) $298 (+28.1%) Shares 14,163 (-6.2%) Est. Cost $19.69 Unrealized -11.4%

BIIB BIOGEN INC 0.3%

Value ($000) $4,207 (+1.6%) Shares 23,905 (-19.2%) Est. Cost $228.60 Unrealized -28.5%

ELVN ENLIVEN THERAPEUTICS INC 0.0%

Value ($000) $149 (-29.9%) Shares 9,671 (-6.9%) Est. Cost $18.43 Unrealized +8.1%

ERAS ERASCA INC 0.0%

Value ($000) $172 (+58.7%) Shares 46,231 (-7.0%) Est. Cost $2.58 Unrealized +8.9%

GLUE MONTE ROSA THERAPEUTICS INC 0.0%

Value ($000) $292 (+27.8%) Shares 18,611 (-39.6%) Est. Cost $5.62 Unrealized +139.8%

ANAB ANAPTYSBIO INC 0.0%

Value ($000) $364 (+20.1%) Shares 7,512 (-24.2%) Est. Cost $24.96 Unrealized +56.2%

ANIP ANI PHARMACEUTICALS INC 0.0%

Value ($000) $289 (-17.0%) Shares 3,660 (-3.7%) Est. Cost $58.12 Unrealized +49.0%

DSGN DESIGN THERAPEUTICS INC 0.0%

Value ($000) $322 (+22.1%) Shares 34,282 (-2.0%) Est. Cost $5.26 Unrealized +48.8%

IRWD IRONWOOD PHARMACEUTICALS INC 0.0%

Value ($000) $89 (+139.5%) Shares 26,508 (-6.9%) Est. Cost $8.19 Unrealized -68.3%

MEDP MEDPACE HOLDINGS INC 0.2%

Value ($000) $2,578 (+1.8%) Shares 4,590 (-6.8%) Est. Cost $329.00 Unrealized +72.5%

PHAT PHATHOM PHARMACEUTICALS INC 0.0%

Value ($000) $192 (+31.4%) Shares 11,592 (-6.8%) Est. Cost $11.33 Unrealized +26.0%

COLL COLLEGIUM PHARMACEUTICAL INC 0.0%

Value ($000) $238 (+23.4%) Shares 5,151 (-6.7%) Est. Cost $31.24 Unrealized +33.9%

NTRA NATERA INC 0.0%

Value ($000) $367 (+13.9%) Shares 1,600 (-20.0%) Est. Cost $157.02 Unrealized +32.8%

SIGA SIGA TECHNOLOGIES INC 0.0%

Value ($000) $71 (-37.9%) Shares 11,669 (-7.0%) Est. Cost $6.14 Unrealized +15.8%

CGEM CULLINAN THERAPEUTICS INC 0.0%

Value ($000) $100 (+62.2%) Shares 9,626 (-7.0%) Est. Cost $14.35 Unrealized -37.2%

RIGL RIGEL PHARMACEUTICALS INC 0.0%

Value ($000) $127 (+42.2%) Shares 2,958 (-5.9%) Est. Cost $19.18 Unrealized +96.6%

BMRN BIOMARIN PHARMACEUTICAL INC 0.1%

Value ($000) $1,860 (+2.1%) Shares 31,305 (-7.0%) Est. Cost $84.28 Unrealized -35.4%

KMTS KESTRA MEDICAL TECHNOLOGIES 0.0%

Value ($000) $13 (-72.1%) Shares 500 (-75.0%) Est. Cost $17.88 Unrealized +44.0%

EXEL EXELIXIS INC 0.1%

Value ($000) $1,915 (-1.7%) Shares 43,689 (-7.4%) Est. Cost $23.75 Unrealized +74.1%

RGNX REGENXBIO INC 0.0%

Value ($000) $119 (+39.0%) Shares 8,249 (-6.8%) Est. Cost $15.23 Unrealized -18.2%

VNDA VANDA PHARMACEUTICALS INC 0.0%

Value ($000) $85 (+64.3%) Shares 9,630 (-7.0%) Est. Cost $4.83 Unrealized +14.0%

CRNX CRINETICS PHARMACEUTICALS IN 0.1%

Value ($000) $720 (+4.7%) Shares 15,463 (-6.3%) Est. Cost $43.84 Unrealized +1.6%

ARGX ARGENX SE - ADR 0.3%

Value ($000) $3,989 (+0.8%) Shares 4,744 (-11.6%) Est. Cost $465.97 Unrealized —

XNCR XENCOR INC 0.0%

Value ($000) $178 (+21.5%) Shares 11,636 (-6.9%) Est. Cost $20.55 Unrealized -27.3%

ENTA ENANTA PHARMACEUTICALS INC 0.0%

Value ($000) $74 (-29.2%) Shares 4,703 (-46.2%) Est. Cost $8.77 Unrealized +44.7%

DAWN DAY ONE BIOPHARMACEUTICALS I 0.0%

Value ($000) $156 (+23.2%) Shares 16,731 (-6.8%) Est. Cost $14.02 Unrealized -40.4%

SUPN SUPERNUS PHARMACEUTICALS INC 0.0%

Value ($000) $613 (-4.4%) Shares 12,343 (-8.1%) Est. Cost $32.21 Unrealized +51.0%

GRFS GRIFOLS SA-ADR 0.0%

Value ($000) $186 (-12.7%) Shares 19,879 (-7.0%) Est. Cost $8.87 Unrealized —

TBPH THERAVANCE BIOPHARMA INC 0.0%

Value ($000) $154 (+19.9%) Shares 8,257 (-6.5%) Est. Cost $9.28 Unrealized +78.8%

KALV KALVISTA PHARMACEUTICALS INC 0.0%

Value ($000) $133 (+23.8%) Shares 8,236 (-6.7%) Est. Cost $11.49 Unrealized +15.2%

TRDA ENTRADA THERAPEUTICS INC 0.0%

Value ($000) $64 (+65.6%) Shares 6,228 (-6.6%) Est. Cost $17.18 Unrealized —

TKNO ALPHA TEKNOVA INC 0.0%

Value ($000) $33 (-42.9%) Shares 8,723 (-7.0%) Est. Cost $6.96 Unrealized -30.1%

PACB PACIFIC BIOSCIENCES OF CALIF 0.0%

Value ($000) $92 (+36.5%) Shares 49,196 (-6.6%) Est. Cost $4.67 Unrealized -58.8%

ADPT ADAPTIVE BIOTECHNOLOGIES 0.0%

Value ($000) $430 (-5.1%) Shares 26,477 (-12.6%) Est. Cost $4.80 Unrealized +239.7%

DNLI DENALI THERAPEUTICS INC 0.0%

Value ($000) $395 (+6.0%) Shares 23,898 (-6.8%) Est. Cost $22.52 Unrealized -25.0%

XENE XENON PHARMACEUTICALS INC 0.0%

Value ($000) $564 (+4.0%) Shares 12,592 (-6.8%) Est. Cost $40.18 Unrealized +4.5%

KYTX KYVERNA THERAPEUTICS INC 0.0%

Value ($000) $67 (+47.5%) Shares 7,137 (-5.8%) Est. Cost $4.79 Unrealized +55.0%

PCRX PACIRA BIOSCIENCES INC 0.0%

Value ($000) $181 (-10.6%) Shares 7,010 (-11.0%) Est. Cost $25.33 Unrealized -6.1%

PAHC PHIBRO ANIMAL HEALTH CORP-A 0.0%

Value ($000) $124 (-13.8%) Shares 3,332 (-6.7%) Est. Cost $15.67 Unrealized +159.2%

VCEL VERICEL CORP 0.0%

Value ($000) $297 (+6.6%) Shares 8,241 (-6.8%) Est. Cost $42.92 Unrealized -14.4%

TWST TWIST BIOSCIENCE CORP 0.0%

Value ($000) $316 (+6.2%) Shares 9,964 (-5.8%) Est. Cost $37.30 Unrealized -16.3%

TECX TECTONIC THERAPEUTIC INC 0.0%

Value ($000) $126 (+16.9%) Shares 6,050 (-12.1%) Est. Cost $29.91 Unrealized -37.9%

XERS XERIS BIOPHARMA HOLDINGS INC 0.0%

Value ($000) $212 (-7.9%) Shares 27,037 (-4.5%) Est. Cost $2.55 Unrealized +208.5%

NVCR NOVOCURE LTD 0.0%

Value ($000) $236 (-6.8%) Shares 18,247 (-6.9%) Est. Cost $19.04 Unrealized -32.6%

APLS APELLIS PHARMACEUTICALS INC 0.0%

Value ($000) $518 (+3.4%) Shares 20,617 (-6.9%) Est. Cost $46.83 Unrealized -49.9%

URGN UROGEN PHARMA LTD 0.0%

Value ($000) $179 (+10.4%) Shares 7,627 (-5.9%) Est. Cost $13.92 Unrealized +55.9%

HROW HARROW INC 0.0%

Value ($000) $296 (-5.4%) Shares 6,035 (-7.0%) Est. Cost $22.80 Unrealized +84.1%

AMPH AMPHASTAR PHARMACEUTICALS IN 0.0%

Value ($000) $201 (-7.7%) Shares 7,488 (-8.1%) Est. Cost $48.01 Unrealized -46.4%

MIRM MIRUM PHARMACEUTICALS INC 0.1%

Value ($000) $662 (+2.5%) Shares 8,375 (-4.9%) Est. Cost $34.07 Unrealized +110.7%

GERN GERON CORP 0.0%

Value ($000) $137 (-10.4%) Shares 104,020 (-7.0%) Est. Cost $3.19 Unrealized -60.6%

SANA SANA BIOTECHNOLOGY INC 0.0%

Value ($000) $177 (+9.7%) Shares 43,404 (-4.3%) Est. Cost $5.24 Unrealized -14.6%

CDXS CODEXIS INC 0.0%

Value ($000) $24 (-37.9%) Shares 14,718 (-7.0%) Est. Cost $4.12 Unrealized -50.5%

CNTA CENTESSA PHARMACEUTICALS-ADR 0.0%

Value ($000) $393 (-3.6%) Shares 15,721 (-6.5%) Est. Cost $13.66 Unrealized —

ARVN ARVINAS INC 0.0%

Value ($000) $124 (+13.2%) Shares 10,465 (-18.7%) Est. Cost $29.43 Unrealized -62.9%

PSNL PERSONALIS INC 0.0%

Value ($000) $115 (+13.7%) Shares 14,471 (-6.9%) Est. Cost $4.64 Unrealized +88.6%

CMPS COMPASS PATHWAYS PLC 0.0%

Value ($000) $106 (+15.0%) Shares 15,353 (-4.5%) Est. Cost $3.38 Unrealized —

SPRY ARS PHARMACEUTICALS INC 0.0%

Value ($000) $188 (+7.8%) Shares 16,107 (-7.0%) Est. Cost $8.84 Unrealized +10.0%

KURA KURA ONCOLOGY INC 0.0%

Value ($000) $147 (+9.4%) Shares 14,179 (-6.8%) Est. Cost $15.78 Unrealized -33.5%

SLDB SOLID BIOSCIENCES INC 0.0%

Value ($000) $72 (-15.0%) Shares 12,695 (-7.0%) Est. Cost $4.93 Unrealized +10.0%

ASND ASCENDIS PHARMA A/S - ADR 0.2%

Value ($000) $2,133 (+0.6%) Shares 10,004 (-6.2%) Est. Cost $138.88 Unrealized —

PYXS PYXIS ONCOLOGY INC 0.0%

Value ($000) $12 (-51.7%) Shares 10,146 (-6.7%) Est. Cost $2.81 Unrealized +25.5%

MGTX MEIRAGTX HOLDINGS PLC 0.0%

Value ($000) $104 (-10.1%) Shares 13,116 (-7.0%) Est. Cost $5.15 Unrealized +61.4%

BCRX BIOCRYST PHARMACEUTICALS INC 0.0%

Value ($000) $268 (-4.2%) Shares 34,308 (-6.8%) Est. Cost $6.83 Unrealized +5.9%

RYTM RHYTHM PHARMACEUTICALS INC 0.1%

Value ($000) $1,164 (-1.0%) Shares 10,875 (-6.6%) Est. Cost $41.70 Unrealized +154.4%

KROS KEROS THERAPEUTICS INC 0.0%

Value ($000) $101 (-10.3%) Shares 4,964 (-30.3%) Est. Cost $48.19 Unrealized -63.6%

ZVRA ZEVRA THERAPEUTICS INC 0.0%

Value ($000) $82 (-12.2%) Shares 9,174 (-6.8%) Est. Cost $8.53 Unrealized +10.9%

AURA AURA BIOSCIENCES INC 0.0%

Value ($000) $56 (-16.2%) Shares 10,348 (-5.0%) Est. Cost $8.72 Unrealized -31.9%

MESO MESOBLAST LTD- SPON ADR 0.0%

Value ($000) $144 (+8.1%) Shares 7,992 (-3.4%) Est. Cost $17.55 Unrealized —

GLPG GALAPAGOS NV-SPON ADR 0.0%

Value ($000) $77 (-11.4%) Shares 2,356 (-6.2%) Est. Cost $33.73 Unrealized —

AQST AQUESTIVE THERAPEUTICS INC 0.0%

Value ($000) $128 (+8.3%) Shares 19,880 (-6.2%) Est. Cost $4.46 Unrealized +39.8%

BCYC BICYCLE THERAPEUTICS PLC-ADR 0.0%

Value ($000) $53 (-14.9%) Shares 7,540 (-7.0%) Est. Cost $20.02 Unrealized —

PRTA PROTHENA CORP PLC 0.0%

Value ($000) $84 (-9.0%) Shares 8,772 (-7.0%) Est. Cost $29.26 Unrealized -65.2%

AUTL AUTOLUS THERAPEUTICS PLC 0.0%

Value ($000) $65 (+13.5%) Shares 32,687 (-7.0%) Est. Cost $5.05 Unrealized —

KNSA KINIKSA PHARMACEUTICALS INTE 0.0%

Value ($000) $304 (+2.6%) Shares 7,359 (-3.4%) Est. Cost $21.16 Unrealized +89.5%

VYGR VOYAGER THERAPEUTICS INC 0.0%

Value ($000) $38 (-16.9%) Shares 9,603 (-1.2%) Est. Cost $7.44 Unrealized —

CGON CG ONCOLOGY INC 0.0%

Value ($000) $546 (+1.4%) Shares 13,145 (-1.6%) Est. Cost $33.84 Unrealized +22.3%

AVIR ATEA PHARMACEUTICALS INC 0.0%

Value ($000) $45 (+12.7%) Shares 12,731 (-8.5%) Est. Cost $3.60 Unrealized -11.8%

MNKD MANNKIND CORP 0.0%

Value ($000) $284 (-1.8%) Shares 50,037 (-7.0%) Est. Cost $4.87 Unrealized +13.0%

LRMR LARIMAR THERAPEUTICS INC 0.0%

Value ($000) $53 (+9.7%) Shares 13,947 (-7.0%) Est. Cost $6.19 Unrealized -37.2%

AVBP ARRIVENT BIOPHARMA INC 0.0%

Value ($000) $135 (+3.2%) Shares 6,727 (-5.4%) Est. Cost $28.28 Unrealized -26.4%

MRVI MARAVAI LIFESCIENCES HLDGS-A 0.0%

Value ($000) $77 (+5.5%) Shares 23,631 (-6.8%) Est. Cost $7.96 Unrealized -57.7%

NMRA NEUMORA THERAPEUTICS INC 0.0%

Value ($000) $49 (-5.7%) Shares 27,227 (-4.1%) Est. Cost $11.98 Unrealized -81.7%

CRMD CORMEDIX INC 0.0%

Value ($000) $149 (-1.9%) Shares 12,839 (-1.9%) Est. Cost $10.10 Unrealized +9.5%

VIR VIR BIOTECHNOLOGY INC 0.0%

Value ($000) $137 (-1.7%) Shares 22,670 (-6.9%) Est. Cost $9.87 Unrealized -39.7%

LGND LIGAND PHARMACEUTICALS 0.0%

Value ($000) $606 (-0.3%) Shares 3,207 (-6.6%) Est. Cost $83.79 Unrealized +129.3%

ALLO ALLOGENE THERAPEUTICS INC 0.0%

Value ($000) $50 (+4.0%) Shares 36,620 (-5.8%) Est. Cost $3.29 Unrealized -59.9%

ARDX ARDELYX INC 0.0%

Value ($000) $231 (-0.8%) Shares 39,593 (-6.3%) Est. Cost $5.88 Unrealized -5.3%

ABUS ARBUTUS BIOPHARMA CORP 0.0%

Value ($000) $151 (-1.2%) Shares 31,339 (-6.7%) Est. Cost $2.95 Unrealized +52.3%

FHTX FOGHORN THERAPEUTICS INC 0.0%

Value ($000) $50 (+2.7%) Shares 9,215 (-7.0%) Est. Cost $7.28 Unrealized -37.8%

EOLS EVOLUS INC 0.0%

Value ($000) $70 (+0.9%) Shares 10,562 (-6.8%) Est. Cost $12.11 Unrealized -44.1%

ACIU AC IMMUNE SA 0.0%

Value ($000) $51 (+1.0%) Shares 16,362 (-7.0%) Est. Cost $3.38 Unrealized -6.6%

RCKT ROCKET PHARMACEUTICALS INC 0.0%

Value ($000) $62 (+0.4%) Shares 17,635 (-6.8%) Est. Cost $20.61 Unrealized -83.4%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
AVGO	BROADCOM INC	115,185 (-21.8%)	$39,866 (-18.0%)	3.1%	$170.46	+109.4%	Common Stock	11135F101
SLV	ISHARES SILVER TRUST	23,000 (-87.1%)	$1,482 (-80.3%)	0.1%	$38.34	—	ETP	46428Q109
MSFT	MICROSOFT CORP	144,458 (-1.1%)	$69,863 (-7.7%)	5.4%	$373.17	+34.1%	Common Stock	594918104
AMZN	AMAZON.COM INC	214,076 (-12.2%)	$49,413 (-7.7%)	3.8%	$159.54	+43.4%	Common Stock	023135106
ORCL	ORACLE CORP	9,360 (-55.3%)	$1,824 (-69.0%)	0.1%	$154.36	+54.2%	Common Stock	68389X105
REGN	REGENERON PHARMACEUTICALS	19,753 (-7.5%)	$15,247 (+27.0%)	1.2%	$888.90	-23.7%	Common Stock	75886F107
BABA	ALIBABA GROUP HOLDING-SP ADR	22,282 (-27.9%)	$3,266 (-40.9%)	0.3%	$178.73	—	ADR	01609W102
BSX	BOSTON SCIENTIFIC CORP	10,000 (-68.8%)	$954 (-69.5%)	0.1%	$96.10	+2.0%	Common Stock	101137107
APP	APPLOVIN CORP-CLASS A	18,805 (-8.8%)	$12,671 (-14.5%)	1.0%	$148.31	+324.9%	Common Stock	03831W108
BTI	BRITISH AMERICAN TOB-SP ADR	61,857 (-42.2%)	$3,538 (-37.7%)	0.3%	$49.37	—	ADR	110448107
AAPL	APPLE INC	242,967 (-3.4%)	$66,053 (+3.1%)	5.1%	$210.12	+27.7%	Common Stock	037833100
COST	COSTCO WHOLESALE CORP	14,919 (-5.7%)	$12,865 (-12.1%)	1.0%	$753.38	+20.2%	Common Stock	22160K105
SE	SEA LTD-ADR	21,100 (-13.5%)	$2,692 (-38.3%)	0.2%	$102.56	—	ADR	81141R100
YMM	FULL TRUCK ALLIANCE -SPN ADR	187,000 (-30.0%)	$2,007 (-42.1%)	0.2%	$7.86	—	ADR	35969L108
MRK	MERCK & CO. INC.	11,512 (-63.3%)	$1,223 (-54.0%)	0.1%	$86.78	+7.4%	Common Stock	58933Y105
ALAB	ASTERA LABS INC	4,200 (-58.8%)	$699 (-65.0%)	0.1%	$84.39	+98.2%	Common Stock	04626A103
FTNT	FORTINET INC	21,044 (-32.6%)	$1,671 (-36.4%)	0.1%	$86.26	-3.9%	Common Stock	34959E109
ABBV	ABBVIE INC	7,106 (-34.8%)	$1,624 (-35.7%)	0.1%	$175.92	+29.3%	Common Stock	00287Y109
FUTU	FUTU HOLDINGS LTD-ADR	15,740 (-20.4%)	$2,585 (-24.8%)	0.2%	$173.91	—	ADR	36118L106
THC	TENET HEALTHCARE CORP	8,000 (-33.3%)	$1,590 (-34.8%)	0.1%	$150.35	+34.4%	Common Stock	88033G407
AS	AMER SPORTS INC	11,537 (-68.2%)	$431 (-65.9%)	0.0%	$15.70	+118.6%	Common Stock	G0260P102
GH	GUARDANT HEALTH INC	21,081 (-3.6%)	$2,153 (+57.7%)	0.2%	$28.53	+213.6%	Common Stock	40131M109
TEM	TEMPUS AI INC	28,168 (-4.7%)	$1,663 (-30.3%)	0.1%	$49.61	+57.7%	Common Stock	88023B103
RVMD	REVOLUTION MEDICINES INC	34,001 (-20.5%)	$2,708 (+35.6%)	0.2%	$41.25	+59.0%	Common Stock	76155X100
UBER	UBER TECHNOLOGIES INC	36,365 (-2.4%)	$2,971 (-18.6%)	0.2%	$45.99	+95.8%	Common Stock	90353T100
TME	TENCENT MUSIC ENTERTAINM-ADR	92,100 (-6.0%)	$1,615 (-29.4%)	0.1%	$20.00	—	ADR	88034P109
BBIO	BRIDGEBIO PHARMA INC	31,402 (-6.3%)	$2,402 (+38.0%)	0.2%	$28.45	+130.7%	Common Stock	10806X102
ADBE	ADOBE INC	11,846 (-12.9%)	$4,146 (-13.6%)	0.3%	$514.67	-33.9%	Common Stock	00724F101
LI	LI AUTO INC - ADR	10,000 (-66.7%)	$169 (-77.7%)	0.0%	$24.02	—	ADR	50202M102
SMMT	SUMMIT THERAPEUTICS INC	121,307 (-6.8%)	$2,122 (-21.1%)	0.2%	$8.69	+116.5%	Common Stock	86627T108
SNY	SANOFI-ADR	55,120 (-19.7%)	$2,671 (-17.5%)	0.2%	$52.01	—	ADR	80105N105
ARWR	ARROWHEAD PHARMACEUTICALS IN	30,130 (-28.7%)	$2,000 (+37.3%)	0.2%	$24.64	+98.9%	Common Stock	04280A100
CLS	CELESTICA INC	12,110 (-2.3%)	$3,580 (+17.2%)	0.3%	$96.91	+211.0%	Common Stock	15101Q207
ON	ON SEMICONDUCTOR	2,500 (-81.2%)	$135 (-79.4%)	0.0%	$60.19	-14.8%	Common Stock	682189105
RERE	ATRENEW INC	369,300 (-31.1%)	$1,957 (-20.6%)	0.2%	$4.60	—	ADR	00138L108
NTLA	INTELLIA THERAPEUTICS INC	18,874 (-51.4%)	$170 (-74.7%)	0.0%	$19.97	-31.1%	Common Stock	45826J105
UTHR	UNITED THERAPEUTICS CORP	7,516 (-24.3%)	$3,662 (-12.0%)	0.3%	$285.40	+63.2%	Common Stock	91307C102
CVS	CVS HEALTH CORP	16,000 (-31.3%)	$1,270 (-27.7%)	0.1%	$57.99	+35.7%	Common Stock	126650100
TERN	TERNS PHARMACEUTICALS INC	14,878 (-3.0%)	$601 (+421.8%)	0.0%	$6.80	+240.0%	Common Stock	880881107
ONC	BEONE MEDICINES LTD-ADR	5,129 (-12.9%)	$1,558 (-22.4%)	0.1%	$191.08	—	ADR	07725L102
MCD	MCDONALD'S CORP	1,861 (-44.3%)	$569 (-44.0%)	0.0%	$273.71	+11.5%	Common Stock	580135101
AXSM	AXSOME THERAPEUTICS INC	8,215 (-6.1%)	$1,500 (+41.2%)	0.1%	$80.54	+73.4%	Common Stock	05464T104
XBI	SS SPDR S&P BIOTECH ETF	608 (-87.6%)	$74 (-85.0%)	0.0%	$99.34	—	ETP	78464A870
APH	AMPHENOL CORP-CL A	47,000 (-2.1%)	$6,362 (+7.0%)	0.5%	$61.93	+115.6%	Common Stock	032095101
MNDY	MONDAY.COM LTD	4,500 (-18.2%)	$664 (-37.7%)	0.1%	$266.37	-36.8%	Common Stock	M7S64H106
PG	PROCTER & GAMBLE CO/THE	6,843 (-23.8%)	$981 (-29.0%)	0.1%	$154.07	-4.5%	Common Stock	742718109
MDGL	MADRIGAL PHARMACEUTICALS INC	3,701 (-5.3%)	$2,155 (+20.3%)	0.2%	$226.42	+125.6%	Common Stock	558868105
INCY	INCYTE CORP	32,991 (-3.6%)	$3,259 (+12.2%)	0.3%	$61.79	+56.6%	Common Stock	45337C102
CRDO	CREDO TECHNOLOGY GROUP HOLDI	10,500 (-18.0%)	$1,511 (-18.9%)	0.1%	$58.32	+163.7%	Common Stock	G25457105
VTRS	VIATRIS INC	187,680 (-8.2%)	$2,337 (+15.5%)	0.2%	$10.25	+4.6%	Common Stock	92556V106
LENZ	LENZ THERAPEUTICS INC	5,099 (-36.3%)	$82 (-78.1%)	0.0%	$32.27	-9.7%	Common Stock	52635N103
FOLD	AMICUS THERAPEUTICS INC	50,275 (-6.9%)	$716 (+68.2%)	0.1%	$11.47	-14.4%	Common Stock	03152W109
BLTE	BELITE BIO INC - ADR	500 (-90.0%)	$80 (-78.4%)	0.0%	$74.00	—	ADR	07782B104
JAZZ	JAZZ PHARMACEUTICALS PLC	9,902 (-6.9%)	$1,683 (+20.1%)	0.1%	$119.64	+28.1%	Common Stock	G50871105
OCUL	OCULAR THERAPEUTIX INC	35,716 (-41.0%)	$434 (-38.7%)	0.0%	$7.34	+65.5%	Common Stock	67576A100
KRYS	KRYSTAL BIOTECH INC	4,725 (-6.9%)	$1,165 (+30.1%)	0.1%	$151.69	+38.8%	Common Stock	501147102
ELV	ELEVANCE HEALTH INC	2,000 (-33.3%)	$701 (-27.7%)	0.1%	$405.10	-16.9%	Common Stock	036752103
IRTC	IRHYTHM HOLDINGS INC	200 (-87.5%)	$35 (-87.1%)	0.0%	$158.94	+11.5%	Common Stock	450056106
IMVT	IMMUNOVANT INC	28,561 (-6.5%)	$726 (+47.4%)	0.1%	$30.99	-28.0%	Common Stock	45258J102
DEO	DIAGEO PLC-SPONSORED ADR	1,884 (-54.2%)	$163 (-58.6%)	0.0%	$146.67	—	ADR	25243Q205
HALO	HALOZYME THERAPEUTICS INC	19,162 (-6.5%)	$1,290 (-14.2%)	0.1%	$45.54	+47.7%	Common Stock	40637H109
BHVN	BIOHAVEN LTD	8,000 (-60.0%)	$90 (-69.9%)	0.0%	$17.82	-30.5%	Common Stock	G1110E107
TTMI	TTM TECHNOLOGIES	23,000 (-4.2%)	$1,587 (+14.8%)	0.1%	$46.47	+40.4%	Common Stock	87305R109
TVTX	TRAVERE THERAPEUTICS INC	15,079 (-3.5%)	$576 (+54.3%)	0.0%	$11.26	+188.8%	Common Stock	89422G107
—	INDIVIOR PLC	20,345 (-7.0%)	$730 (+38.4%)	0.1%	$12.43	—	Common Stock	G4766E116
VERA	VERA THERAPEUTICS INC	10,417 (-6.9%)	$528 (+62.3%)	0.0%	$32.62	+8.9%	Common Stock	92337R101
ORIC	ORIC PHARMACEUTICALS INC	15,870 (-41.3%)	$130 (-60.0%)	0.0%	$10.07	+14.3%	Common Stock	68622P109
OMER	OMEROS CORP	16,553 (-24.5%)	$284 (+216.2%)	0.0%	$5.51	+56.3%	Common Stock	682143102
RMBS	RAMBUS INC	7,000 (-12.5%)	$643 (-22.8%)	0.0%	$77.09	+27.7%	Common Stock	750917106
ALVO	ALVOTECH SA	51,006 (-7.0%)	$262 (-41.8%)	0.0%	$12.21	-48.3%	Common Stock	L01800108
ACLX	ARCELLX INC	9,422 (-3.1%)	$614 (-23.0%)	0.0%	$60.22	+32.5%	Common Stock	03940C100
ARQT	ARCUTIS BIOTHERAPEUTICS INC	19,960 (-5.0%)	$580 (+46.3%)	0.0%	$7.68	+233.5%	Common Stock	03969K108
LEGN	LEGEND BIOTECH CORP-ADR	13,720 (-7.0%)	$298 (-38.0%)	0.0%	$52.47	—	ADR	52490G102
ZLAB	ZAI LAB LTD-ADR	6,380 (-23.9%)	$113 (-60.4%)	0.0%	$25.38	—	ADR	98887Q104
BEAM	BEAM THERAPEUTICS INC	16,535 (-35.7%)	$458 (-26.6%)	0.0%	$24.88	+2.6%	Common Stock	07373V105
PCVX	VAXCYTE INC	21,331 (-6.3%)	$984 (+20.1%)	0.1%	$63.74	-29.8%	Common Stock	92243G108
GRAL	GRAIL INC	7,952 (-9.8%)	$681 (+30.5%)	0.1%	$20.88	+313.8%	Common Stock	384747101
AGIO	AGIOS PHARMACEUTICALS INC	9,502 (-6.7%)	$259 (-36.7%)	0.0%	$34.10	+2.9%	Common Stock	00847X104
PTGX	PROTAGONIST THERAPEUTICS INC	13,787 (-13.3%)	$1,204 (+14.0%)	0.1%	$34.08	+140.2%	Common Stock	74366E102
PTCT	PTC THERAPEUTICS INC	13,183 (-5.3%)	$1,001 (+17.2%)	0.1%	$31.09	+133.7%	Common Stock	69366J200
RARE	ULTRAGENYX PHARMACEUTICAL IN	15,721 (-6.9%)	$362 (-28.8%)	0.0%	$46.48	-29.3%	Common Stock	90400D108
DYN	DYNE THERAPEUTICS INC	23,273 (-6.7%)	$455 (+44.3%)	0.0%	$24.70	-23.3%	Common Stock	26818M108
NBIX	NEUROCRINE BIOSCIENCES INC	16,247 (-6.5%)	$2,304 (-5.6%)	0.2%	$127.72	+13.4%	Common Stock	64125C109
EWTX	EDGEWISE THERAPEUTICS INC	17,251 (-6.6%)	$428 (+42.9%)	0.0%	$16.74	+19.9%	Common Stock	28036F105
PRCT	PROCEPT BIOROBOTICS CORP	5,000 (-37.5%)	$157 (-44.9%)	0.0%	$56.54	-41.3%	Common Stock	74276L105
TARS	TARSUS PHARMACEUTICALS INC	6,917 (-6.5%)	$566 (+28.8%)	0.0%	$28.09	+165.8%	Common Stock	87650L103
FTRE	FORTREA HOLDINGS INC	15,057 (-5.4%)	$260 (+93.8%)	0.0%	$27.70	-55.4%	Common Stock	34965K107
JANX	JANUX THERAPEUTICS INC	9,801 (-7.0%)	$135 (-47.5%)	0.0%	$29.16	-19.3%	Common Stock	47103J105
MRNA	MODERNA INC	63,661 (-6.7%)	$1,877 (+6.6%)	0.1%	$94.45	-71.2%	Common Stock	60770K107
ALKS	ALKERMES PLC	26,906 (-7.0%)	$753 (-13.3%)	0.1%	$27.16	+10.3%	Common Stock	G01767105
ARCT	ARCTURUS THERAPEUTICS HOLDIN	4,630 (-40.3%)	$28 (-80.2%)	0.0%	$22.36	-51.7%	Common Stock	03969T109
CYTK	CYTOKINETICS INC	19,923 (-5.0%)	$1,266 (+9.8%)	0.1%	$54.55	+14.0%	Common Stock	23282W605
GMED	GLOBUS MEDICAL INC - A	2,000 (-60.0%)	$175 (-39.0%)	0.0%	$57.58	+31.8%	Common Stock	379577208
WVE	WAVE LIFE SCIENCES LTD	39,742 (-49.0%)	$676 (+18.5%)	0.1%	$8.43	+20.6%	Common Stock	Y95308105
ACAD	ACADIA PHARMACEUTICALS INC	27,568 (-6.8%)	$736 (+16.7%)	0.1%	$20.65	+15.7%	Common Stock	004225108
INBX	INHIBRX BIOSCIENCES INC	2,370 (-6.7%)	$187 (+118.9%)	0.0%	$15.23	+347.3%	Common Stock	45720N103
TYRA	TYRA BIOSCIENCES INC	8,697 (-6.9%)	$229 (+74.9%)	0.0%	$17.72	+3.7%	Common Stock	90240B106
HTHT	H WORLD GROUP LTD-ADR	6,398 (-37.3%)	$301 (-24.5%)	0.0%	$37.04	—	ADR	44332N106
ABCL	ABCELLERA BIOLOGICS INC	48,777 (-6.9%)	$167 (-36.7%)	0.0%	$4.17	+6.9%	Common Stock	00288U106
ZYME	ZYMEWORKS INC	12,195 (-7.4%)	$321 (+42.7%)	0.0%	$10.16	+114.7%	Common Stock	98985Y108
AMRX	AMNEAL PHARMACEUTICALS INC	51,225 (-7.0%)	$645 (+17.1%)	0.0%	$8.38	+36.6%	Common Stock	03168L105
ADMA	ADMA BIOLOGICS INC	38,782 (-7.3%)	$707 (+15.4%)	0.1%	$9.93	+69.7%	Common Stock	000899104
—	DYNAVAX TECHNOLOGIES CORP	19,134 (-6.9%)	$294 (+44.2%)	0.0%	$12.51	—	Common Stock	268158201
IBRX	IMMUNITYBIO INC	160,500 (-3.1%)	$318 (-22.0%)	0.0%	$3.83	-40.8%	Common Stock	45256X103
TSHA	TAYSHA GENE THERAPIES INC	44,635 (-6.7%)	$245 (+57.0%)	0.0%	$2.12	+129.6%	Common Stock	877619106
AUPH	AURINIA PHARMACEUTICALS INC	21,483 (-6.9%)	$343 (+34.4%)	0.0%	$7.25	+95.4%	Common Stock	05156V102
ALMS	ALUMIS INC	15,840 (-6.7%)	$155 (+128.2%)	0.0%	$7.34	-4.9%	Common Stock	022307102
AVXL	ANAVEX LIFE SCIENCES CORP	14,559 (-3.3%)	$52 (-61.3%)	0.0%	$6.46	-5.1%	Common Stock	032797300
RLAY	RELAY THERAPEUTICS INC	28,243 (-6.5%)	$239 (+51.5%)	0.0%	$7.93	-10.0%	Common Stock	75943R102
RGEN	REPLIGEN CORP	3,600 (-28.0%)	$590 (-11.7%)	0.0%	$123.66	+26.7%	Common Stock	759916109
IDYA	IDEAYA BIOSCIENCES INC	14,285 (-7.0%)	$494 (+18.1%)	0.0%	$35.50	-10.2%	Common Stock	45166A102
TXG	10X GENOMICS INC-CLASS A	18,979 (-5.4%)	$310 (+32.0%)	0.0%	$15.60	-3.2%	Common Stock	88025U109
HRMY	HARMONY BIOSCIENCES HOLDINGS	9,385 (-6.9%)	$351 (+26.4%)	0.0%	$33.01	-0.4%	Common Stock	413197104
CSTL	CASTLE BIOSCIENCES INC	4,756 (-6.5%)	$185 (+59.8%)	0.0%	$22.88	+40.9%	Common Stock	14843C105
NVAX	NOVAVAX INC	26,479 (-7.0%)	$178 (-27.9%)	0.0%	$9.67	-22.0%	Common Stock	670002401
VCYT	VERACYTE INC	12,881 (-6.6%)	$542 (+14.5%)	0.0%	$27.00	+49.3%	Common Stock	92337F107
PRME	PRIME MEDICINE INC	29,414 (-4.0%)	$102 (-39.9%)	0.0%	$5.70	-22.0%	Common Stock	74168J101
REPL	REPLIMUNE GROUP INC	12,782 (-6.6%)	$124 (+116.7%)	0.0%	$11.04	-23.0%	Common Stock	76029N106
TRVI	TREVI THERAPEUTICS INC	20,895 (-2.1%)	$262 (+33.9%)	0.0%	$3.86	+199.5%	Common Stock	89532M101
SNDX	SYNDAX PHARMACEUTICALS INC	14,163 (-6.2%)	$298 (+28.1%)	0.0%	$19.69	-11.4%	Common Stock	87164F105
BIIB	BIOGEN INC	23,905 (-19.2%)	$4,207 (+1.6%)	0.3%	$228.60	-28.5%	Common Stock	09062X103
ELVN	ENLIVEN THERAPEUTICS INC	9,671 (-6.9%)	$149 (-29.9%)	0.0%	$18.43	+8.1%	Common Stock	29337E102
ERAS	ERASCA INC	46,231 (-7.0%)	$172 (+58.7%)	0.0%	$2.58	+8.9%	Common Stock	29479A108
GLUE	MONTE ROSA THERAPEUTICS INC	18,611 (-39.6%)	$292 (+27.8%)	0.0%	$5.62	+139.8%	Common Stock	61225M102
ANAB	ANAPTYSBIO INC	7,512 (-24.2%)	$364 (+20.1%)	0.0%	$24.96	+56.2%	Common Stock	032724106
ANIP	ANI PHARMACEUTICALS INC	3,660 (-3.7%)	$289 (-17.0%)	0.0%	$58.12	+49.0%	Common Stock	00182C103
DSGN	DESIGN THERAPEUTICS INC	34,282 (-2.0%)	$322 (+22.1%)	0.0%	$5.26	+48.8%	Common Stock	25056L103
IRWD	IRONWOOD PHARMACEUTICALS INC	26,508 (-6.9%)	$89 (+139.5%)	0.0%	$8.19	-68.3%	Common Stock	46333X108
MEDP	MEDPACE HOLDINGS INC	4,590 (-6.8%)	$2,578 (+1.8%)	0.2%	$329.00	+72.5%	Common Stock	58506Q109
PHAT	PHATHOM PHARMACEUTICALS INC	11,592 (-6.8%)	$192 (+31.4%)	0.0%	$11.33	+26.0%	Common Stock	71722W107
COLL	COLLEGIUM PHARMACEUTICAL INC	5,151 (-6.7%)	$238 (+23.4%)	0.0%	$31.24	+33.9%	Common Stock	19459J104
NTRA	NATERA INC	1,600 (-20.0%)	$367 (+13.9%)	0.0%	$157.02	+32.8%	Common Stock	632307104
SIGA	SIGA TECHNOLOGIES INC	11,669 (-7.0%)	$71 (-37.9%)	0.0%	$6.14	+15.8%	Common Stock	826917106
CGEM	CULLINAN THERAPEUTICS INC	9,626 (-7.0%)	$100 (+62.2%)	0.0%	$14.35	-37.2%	Common Stock	230031106
RIGL	RIGEL PHARMACEUTICALS INC	2,958 (-5.9%)	$127 (+42.2%)	0.0%	$19.18	+96.6%	Common Stock	766559702
BMRN	BIOMARIN PHARMACEUTICAL INC	31,305 (-7.0%)	$1,860 (+2.1%)	0.1%	$84.28	-35.4%	Common Stock	09061G101
KMTS	KESTRA MEDICAL TECHNOLOGIES	500 (-75.0%)	$13 (-72.1%)	0.0%	$17.88	+44.0%	Common Stock	G52441105
EXEL	EXELIXIS INC	43,689 (-7.4%)	$1,915 (-1.7%)	0.1%	$23.75	+74.1%	Common Stock	30161Q104
RGNX	REGENXBIO INC	8,249 (-6.8%)	$119 (+39.0%)	0.0%	$15.23	-18.2%	Common Stock	75901B107
VNDA	VANDA PHARMACEUTICALS INC	9,630 (-7.0%)	$85 (+64.3%)	0.0%	$4.83	+14.0%	Common Stock	921659108
CRNX	CRINETICS PHARMACEUTICALS IN	15,463 (-6.3%)	$720 (+4.7%)	0.1%	$43.84	+1.6%	Common Stock	22663K107
ARGX	ARGENX SE - ADR	4,744 (-11.6%)	$3,989 (+0.8%)	0.3%	$465.97	—	ADR	04016X101
XNCR	XENCOR INC	11,636 (-6.9%)	$178 (+21.5%)	0.0%	$20.55	-27.3%	Common Stock	98401F105
ENTA	ENANTA PHARMACEUTICALS INC	4,703 (-46.2%)	$74 (-29.2%)	0.0%	$8.77	+44.7%	Common Stock	29251M106
DAWN	DAY ONE BIOPHARMACEUTICALS I	16,731 (-6.8%)	$156 (+23.2%)	0.0%	$14.02	-40.4%	Common Stock	23954D109
SUPN	SUPERNUS PHARMACEUTICALS INC	12,343 (-8.1%)	$613 (-4.4%)	0.0%	$32.21	+51.0%	Common Stock	868459108
GRFS	GRIFOLS SA-ADR	19,879 (-7.0%)	$186 (-12.7%)	0.0%	$8.87	—	ADR	398438408
TBPH	THERAVANCE BIOPHARMA INC	8,257 (-6.5%)	$154 (+19.9%)	0.0%	$9.28	+78.8%	Common Stock	G8807B106
KALV	KALVISTA PHARMACEUTICALS INC	8,236 (-6.7%)	$133 (+23.8%)	0.0%	$11.49	+15.2%	Common Stock	483497103
TRDA	ENTRADA THERAPEUTICS INC	6,228 (-6.6%)	$64 (+65.6%)	0.0%	$17.18	—	Common Stock	29384C108
TKNO	ALPHA TEKNOVA INC	8,723 (-7.0%)	$33 (-42.9%)	0.0%	$6.96	-30.1%	Common Stock	02080L102
PACB	PACIFIC BIOSCIENCES OF CALIF	49,196 (-6.6%)	$92 (+36.5%)	0.0%	$4.67	-58.8%	Common Stock	69404D108
ADPT	ADAPTIVE BIOTECHNOLOGIES	26,477 (-12.6%)	$430 (-5.1%)	0.0%	$4.80	+239.7%	Common Stock	00650F109
DNLI	DENALI THERAPEUTICS INC	23,898 (-6.8%)	$395 (+6.0%)	0.0%	$22.52	-25.0%	Common Stock	24823R105
XENE	XENON PHARMACEUTICALS INC	12,592 (-6.8%)	$564 (+4.0%)	0.0%	$40.18	+4.5%	Common Stock	98420N105
KYTX	KYVERNA THERAPEUTICS INC	7,137 (-5.8%)	$67 (+47.5%)	0.0%	$4.79	+55.0%	Common Stock	501976104
PCRX	PACIRA BIOSCIENCES INC	7,010 (-11.0%)	$181 (-10.6%)	0.0%	$25.33	-6.1%	Common Stock	695127100
PAHC	PHIBRO ANIMAL HEALTH CORP-A	3,332 (-6.7%)	$124 (-13.8%)	0.0%	$15.67	+159.2%	Common Stock	71742Q106
VCEL	VERICEL CORP	8,241 (-6.8%)	$297 (+6.6%)	0.0%	$42.92	-14.4%	Common Stock	92346J108
TWST	TWIST BIOSCIENCE CORP	9,964 (-5.8%)	$316 (+6.2%)	0.0%	$37.30	-16.3%	Common Stock	90184D100
TECX	TECTONIC THERAPEUTIC INC	6,050 (-12.1%)	$126 (+16.9%)	0.0%	$29.91	-37.9%	Common Stock	878972108
XERS	XERIS BIOPHARMA HOLDINGS INC	27,037 (-4.5%)	$212 (-7.9%)	0.0%	$2.55	+208.5%	Common Stock	98422E103
NVCR	NOVOCURE LTD	18,247 (-6.9%)	$236 (-6.8%)	0.0%	$19.04	-32.6%	Common Stock	G6674U108
APLS	APELLIS PHARMACEUTICALS INC	20,617 (-6.9%)	$518 (+3.4%)	0.0%	$46.83	-49.9%	Common Stock	03753U106
URGN	UROGEN PHARMA LTD	7,627 (-5.9%)	$179 (+10.4%)	0.0%	$13.92	+55.9%	Common Stock	M96088105
HROW	HARROW INC	6,035 (-7.0%)	$296 (-5.4%)	0.0%	$22.80	+84.1%	Common Stock	415858109
AMPH	AMPHASTAR PHARMACEUTICALS IN	7,488 (-8.1%)	$201 (-7.7%)	0.0%	$48.01	-46.4%	Common Stock	03209R103
MIRM	MIRUM PHARMACEUTICALS INC	8,375 (-4.9%)	$662 (+2.5%)	0.1%	$34.07	+110.7%	Common Stock	604749101
GERN	GERON CORP	104,020 (-7.0%)	$137 (-10.4%)	0.0%	$3.19	-60.6%	Common Stock	374163103
SANA	SANA BIOTECHNOLOGY INC	43,404 (-4.3%)	$177 (+9.7%)	0.0%	$5.24	-14.6%	Common Stock	799566104
CDXS	CODEXIS INC	14,718 (-7.0%)	$24 (-37.9%)	0.0%	$4.12	-50.5%	Common Stock	192005106
CNTA	CENTESSA PHARMACEUTICALS-ADR	15,721 (-6.5%)	$393 (-3.6%)	0.0%	$13.66	—	ADR	152309100
ARVN	ARVINAS INC	10,465 (-18.7%)	$124 (+13.2%)	0.0%	$29.43	-62.9%	Common Stock	04335A105
PSNL	PERSONALIS INC	14,471 (-6.9%)	$115 (+13.7%)	0.0%	$4.64	+88.6%	Common Stock	71535D106
CMPS	COMPASS PATHWAYS PLC	15,353 (-4.5%)	$106 (+15.0%)	0.0%	$3.38	—	ADR	20451W101
SPRY	ARS PHARMACEUTICALS INC	16,107 (-7.0%)	$188 (+7.8%)	0.0%	$8.84	+10.0%	Common Stock	82835W108
KURA	KURA ONCOLOGY INC	14,179 (-6.8%)	$147 (+9.4%)	0.0%	$15.78	-33.5%	Common Stock	50127T109
SLDB	SOLID BIOSCIENCES INC	12,695 (-7.0%)	$72 (-15.0%)	0.0%	$4.93	+10.0%	Common Stock	83422E204
ASND	ASCENDIS PHARMA A/S - ADR	10,004 (-6.2%)	$2,133 (+0.6%)	0.2%	$138.88	—	ADR	04351P101
PYXS	PYXIS ONCOLOGY INC	10,146 (-6.7%)	$12 (-51.7%)	0.0%	$2.81	+25.5%	Common Stock	747324101
MGTX	MEIRAGTX HOLDINGS PLC	13,116 (-7.0%)	$104 (-10.1%)	0.0%	$5.15	+61.4%	Common Stock	G59665102
BCRX	BIOCRYST PHARMACEUTICALS INC	34,308 (-6.8%)	$268 (-4.2%)	0.0%	$6.83	+5.9%	Common Stock	09058V103
RYTM	RHYTHM PHARMACEUTICALS INC	10,875 (-6.6%)	$1,164 (-1.0%)	0.1%	$41.70	+154.4%	Common Stock	76243J105
KROS	KEROS THERAPEUTICS INC	4,964 (-30.3%)	$101 (-10.3%)	0.0%	$48.19	-63.6%	Common Stock	492327101
ZVRA	ZEVRA THERAPEUTICS INC	9,174 (-6.8%)	$82 (-12.2%)	0.0%	$8.53	+10.9%	Common Stock	488445206
AURA	AURA BIOSCIENCES INC	10,348 (-5.0%)	$56 (-16.2%)	0.0%	$8.72	-31.9%	Common Stock	05153U107
MESO	MESOBLAST LTD- SPON ADR	7,992 (-3.4%)	$144 (+8.1%)	0.0%	$17.55	—	ADR	590717401
GLPG	GALAPAGOS NV-SPON ADR	2,356 (-6.2%)	$77 (-11.4%)	0.0%	$33.73	—	ADR	36315X101
AQST	AQUESTIVE THERAPEUTICS INC	19,880 (-6.2%)	$128 (+8.3%)	0.0%	$4.46	+39.8%	Common Stock	03843E104
BCYC	BICYCLE THERAPEUTICS PLC-ADR	7,540 (-7.0%)	$53 (-14.9%)	0.0%	$20.02	—	ADR	088786108
PRTA	PROTHENA CORP PLC	8,772 (-7.0%)	$84 (-9.0%)	0.0%	$29.26	-65.2%	Common Stock	G72800108
AUTL	AUTOLUS THERAPEUTICS PLC	32,687 (-7.0%)	$65 (+13.5%)	0.0%	$5.05	—	ADR	05280R100
KNSA	KINIKSA PHARMACEUTICALS INTE	7,359 (-3.4%)	$304 (+2.6%)	0.0%	$21.16	+89.5%	Common Stock	G52694109
VYGR	VOYAGER THERAPEUTICS INC	9,603 (-1.2%)	$38 (-16.9%)	0.0%	$7.44	—	Common Stock	92915B106
CGON	CG ONCOLOGY INC	13,145 (-1.6%)	$546 (+1.4%)	0.0%	$33.84	+22.3%	Common Stock	156944100
AVIR	ATEA PHARMACEUTICALS INC	12,731 (-8.5%)	$45 (+12.7%)	0.0%	$3.60	-11.8%	Common Stock	04683R106
MNKD	MANNKIND CORP	50,037 (-7.0%)	$284 (-1.8%)	0.0%	$4.87	+13.0%	Common Stock	56400P706
LRMR	LARIMAR THERAPEUTICS INC	13,947 (-7.0%)	$53 (+9.7%)	0.0%	$6.19	-37.2%	Common Stock	517125100
AVBP	ARRIVENT BIOPHARMA INC	6,727 (-5.4%)	$135 (+3.2%)	0.0%	$28.28	-26.4%	Common Stock	04272N102
MRVI	MARAVAI LIFESCIENCES HLDGS-A	23,631 (-6.8%)	$77 (+5.5%)	0.0%	$7.96	-57.7%	Common Stock	56600D107
NMRA	NEUMORA THERAPEUTICS INC	27,227 (-4.1%)	$49 (-5.7%)	0.0%	$11.98	-81.7%	Common Stock	640979100
CRMD	CORMEDIX INC	12,839 (-1.9%)	$149 (-1.9%)	0.0%	$10.10	+9.5%	Common Stock	21900C308
VIR	VIR BIOTECHNOLOGY INC	22,670 (-6.9%)	$137 (-1.7%)	0.0%	$9.87	-39.7%	Common Stock	92764N102
LGND	LIGAND PHARMACEUTICALS	3,207 (-6.6%)	$606 (-0.3%)	0.0%	$83.79	+129.3%	Common Stock	53220K504
ALLO	ALLOGENE THERAPEUTICS INC	36,620 (-5.8%)	$50 (+4.0%)	0.0%	$3.29	-59.9%	Common Stock	019770106
ARDX	ARDELYX INC	39,593 (-6.3%)	$231 (-0.8%)	0.0%	$5.88	-5.3%	Common Stock	039697107
ABUS	ARBUTUS BIOPHARMA CORP	31,339 (-6.7%)	$151 (-1.2%)	0.0%	$2.95	+52.3%	Common Stock	03879J100
FHTX	FOGHORN THERAPEUTICS INC	9,215 (-7.0%)	$50 (+2.7%)	0.0%	$7.28	-37.8%	Common Stock	344174107
EOLS	EVOLUS INC	10,562 (-6.8%)	$70 (+0.9%)	0.0%	$12.11	-44.1%	Common Stock	30052C107
ACIU	AC IMMUNE SA	16,362 (-7.0%)	$51 (+1.0%)	0.0%	$3.38	-6.6%	Common Stock	H00263105
RCKT	ROCKET PHARMACEUTICALS INC	17,635 (-6.8%)	$62 (+0.4%)	0.0%	$20.61	-83.4%	Common Stock	77313F106

Unchanged Positions (33)

BAR GRANITESHARES GOLD TRUST 1.0%

Value ($000) $12,874 Shares 303,000 Est. Cost $26.03 Unrealized —

NVDA NVIDIA CORP 6.6%

Value ($000) $85,499 Shares 458,438 Est. Cost $109.33 Unrealized +70.2%

ZS ZSCALER INC 0.1%

Value ($000) $1,510 Shares 6,713 Est. Cost $222.39 Unrealized +26.9%

TMO THERMO FISHER SCIENTIFIC INC 0.2%

Value ($000) $2,311 Shares 3,985 Est. Cost $464.78 Unrealized +21.6%

NTES NETEASE INC-ADR 0.3%

Value ($000) $3,592 Shares 26,100 Est. Cost $114.52 Unrealized —

NUVL NUVALENT INC-A 0.1%

Value ($000) $1,184 Shares 11,769 Est. Cost $76.25 Unrealized +29.3%

HSAI HESAI GROUP 0.0%

Value ($000) $448 Shares 20,000 Est. Cost $11.18 Unrealized —

VFC VF CORP 0.0%

Value ($000) $450 Shares 24,906 Est. Cost $20.49 Unrealized -20.9%

AZO AUTOZONE INC 0.0%

Value ($000) $339 Shares 100 Est. Cost $2869.84 Unrealized +31.6%

TNDM TANDEM DIABETES CARE INC 0.0%

Value ($000) $176 Shares 8,000 Est. Cost $13.54 Unrealized +33.3%

GS GOLDMAN SACHS GROUP INC 0.1%

Value ($000) $694 Shares 789 Est. Cost $549.61 Unrealized +48.0%

SIVR ABRDN PHYSICAL SILVER SHARES 0.0%

Value ($000) $203 Shares 3,000 Est. Cost $28.81 Unrealized —

BAC BANK OF AMERICA CORP 0.1%

Value ($000) $1,009 Shares 18,346 Est. Cost $38.48 Unrealized +36.9%

JOYY JOYY INC-ADR 0.1%

Value ($000) $777 Shares 12,000 Est. Cost $59.55 Unrealized —

VNET VNET GROUP INC-ADR 0.0%

Value ($000) $254 Shares 30,000 Est. Cost $10.33 Unrealized —

RBRK RUBRIK INC-A 0.0%

Value ($000) $650 Shares 8,500 Est. Cost $79.05 Unrealized -3.0%

ZTS ZOETIS INC 0.0%

Value ($000) $252 Shares 2,000 Est. Cost $177.97 Unrealized -26.8%

MA MASTERCARD INC - A 0.4%

Value ($000) $5,190 Shares 9,092 Est. Cost $403.86 Unrealized +38.4%

SRPT SAREPTA THERAPEUTICS INC 0.0%

Value ($000) $367 Shares 17,075 Est. Cost $119.41 Unrealized -82.4%

ATEC ALPHATEC HOLDINGS INC 0.0%

Value ($000) $105 Shares 5,000 Est. Cost $13.92 Unrealized +33.0%

XPEV XPENG INC - ADR 0.0%

Value ($000) $203 Shares 10,000 Est. Cost $13.27 Unrealized —

HLT HILTON WORLDWIDE HOLDINGS IN 0.0%

Value ($000) $293 Shares 1,021 Est. Cost $177.88 Unrealized +53.0%

EDIT EDITAS MEDICINE INC 0.0%

Value ($000) $33 Shares 15,907 Est. Cost $6.59 Unrealized -56.2%

CYD CHINA YUCHAI INTL LTD 0.0%

Value ($000) $71 Shares 2,000 Est. Cost $30.22 Unrealized +20.6%

CVX CHEVRON CORP 0.1%

Value ($000) $766 Shares 5,026 Est. Cost $142.02 Unrealized +6.6%

ZETA ZETA GLOBAL HOLDINGS CORP-A 0.0%

Value ($000) $448 Shares 22,000 Est. Cost $20.12 Unrealized -7.1%

ALV AUTOLIV INC 0.0%

Value ($000) $237 Shares 2,000 Est. Cost $73.94 Unrealized +61.5%

TMDX TRANSMEDICS GROUP INC 0.0%

Value ($000) $122 Shares 1,000 Est. Cost $117.06 Unrealized +7.2%

DECK DECKERS OUTDOOR CORP 0.0%

Value ($000) $405 Shares 3,908 Est. Cost $160.72 Unrealized -41.7%

NGNE NEUROGENE INC 0.0%

Value ($000) $52 Shares 2,524 Est. Cost $37.21 Unrealized -33.1%

ALGN ALIGN TECHNOLOGY INC 0.0%

Value ($000) $21 Shares 133 Est. Cost $334.70 Unrealized -57.2%

CMG CHIPOTLE MEXICAN GRILL INC 0.0%

Value ($000) $2 Shares 61 Est. Cost $56.73 Unrealized -36.2%

HSY HERSHEY CO/THE 0.0%

Value ($000) $2 Shares 10 Est. Cost $208.68 Unrealized -12.7%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
BAR	GRANITESHARES GOLD TRUST	303,000	$12,874	1.0%	$26.03	—	ETP	38748G101
NVDA	NVIDIA CORP	458,438	$85,499	6.6%	$109.33	+70.2%	Common Stock	67066G104
ZS	ZSCALER INC	6,713	$1,510	0.1%	$222.39	+26.9%	Common Stock	98980G102
TMO	THERMO FISHER SCIENTIFIC INC	3,985	$2,311	0.2%	$464.78	+21.6%	Common Stock	883556102
NTES	NETEASE INC-ADR	26,100	$3,592	0.3%	$114.52	—	ADR	64110W102
NUVL	NUVALENT INC-A	11,769	$1,184	0.1%	$76.25	+29.3%	Common Stock	670703107
HSAI	HESAI GROUP	20,000	$448	0.0%	$11.18	—	ADR	428050108
VFC	VF CORP	24,906	$450	0.0%	$20.49	-20.9%	Common Stock	918204108
AZO	AUTOZONE INC	100	$339	0.0%	$2869.84	+31.6%	Common Stock	053332102
TNDM	TANDEM DIABETES CARE INC	8,000	$176	0.0%	$13.54	+33.3%	Common Stock	875372203
GS	GOLDMAN SACHS GROUP INC	789	$694	0.1%	$549.61	+48.0%	Common Stock	38141G104
SIVR	ABRDN PHYSICAL SILVER SHARES	3,000	$203	0.0%	$28.81	—	ETP	003264108
BAC	BANK OF AMERICA CORP	18,346	$1,009	0.1%	$38.48	+36.9%	Common Stock	060505104
JOYY	JOYY INC-ADR	12,000	$777	0.1%	$59.55	—	ADR	46591M109
VNET	VNET GROUP INC-ADR	30,000	$254	0.0%	$10.33	—	ADR	90138A103
RBRK	RUBRIK INC-A	8,500	$650	0.0%	$79.05	-3.0%	Common Stock	781154109
ZTS	ZOETIS INC	2,000	$252	0.0%	$177.97	-26.8%	Common Stock	98978V103
MA	MASTERCARD INC - A	9,092	$5,190	0.4%	$403.86	+38.4%	Common Stock	57636Q104
SRPT	SAREPTA THERAPEUTICS INC	17,075	$367	0.0%	$119.41	-82.4%	Common Stock	803607100
ATEC	ALPHATEC HOLDINGS INC	5,000	$105	0.0%	$13.92	+33.0%	Common Stock	02081G201
XPEV	XPENG INC - ADR	10,000	$203	0.0%	$13.27	—	ADR	98422D105
HLT	HILTON WORLDWIDE HOLDINGS IN	1,021	$293	0.0%	$177.88	+53.0%	Common Stock	43300A203
EDIT	EDITAS MEDICINE INC	15,907	$33	0.0%	$6.59	-56.2%	Common Stock	28106W103
CYD	CHINA YUCHAI INTL LTD	2,000	$71	0.0%	$30.22	+20.6%	Common Stock	G21082105
CVX	CHEVRON CORP	5,026	$766	0.1%	$142.02	+6.6%	Common Stock	166764100
ZETA	ZETA GLOBAL HOLDINGS CORP-A	22,000	$448	0.0%	$20.12	-7.1%	Common Stock	98956A105
ALV	AUTOLIV INC	2,000	$237	0.0%	$73.94	+61.5%	Common Stock	052800109
TMDX	TRANSMEDICS GROUP INC	1,000	$122	0.0%	$117.06	+7.2%	Common Stock	89377M109
DECK	DECKERS OUTDOOR CORP	3,908	$405	0.0%	$160.72	-41.7%	Common Stock	243537107
NGNE	NEUROGENE INC	2,524	$52	0.0%	$37.21	-33.1%	Common Stock	64135M105
ALGN	ALIGN TECHNOLOGY INC	133	$21	0.0%	$334.70	-57.2%	Common Stock	016255101
CMG	CHIPOTLE MEXICAN GRILL INC	61	$2	0.0%	$56.73	-36.2%	Common Stock	169656105
HSY	HERSHEY CO/THE	10	$2	0.0%	$208.68	-12.7%	Common Stock	427866108