PUMA BIOTECHNOLOGY INC

Institution	Shares	Value ($000)
Verdad Advisers, LP	55,542	$330
Haven Private, LLC	92,083	$548
EntryPoint Capital, LLC	35,389	$211
Williams & Novak, LLC	10,560	$63
AXQ CAPITAL, LP	16,592	$99
Heron Bay Capital Management	20,056	$119
Abel Hall, LLC	10,793	$64
Stokes Family Office, LLC	28,091	$167
One Wealth Advisors, LLC	19,389	$115
Vise Technologies, Inc.	40,298	$240
CITADEL ADVISORS LLC	162,670	$968
China Universal Asset Management Co., Ltd.	8,211	$49
CANADA PENSION PLAN INVESTMENT BOARD	75,200	$447
Man Group plc	47,324	$282
Engineers Gate Manager LP	18,786	$112
Brandywine Global Investment Management, LLC	21,800	$130
STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM	27,335	$163
IEQ CAPITAL, LLC	11,495	$68
ProShare Advisors LLC	10,062	$60
WEALTH ENHANCEMENT ADVISORY SERVICES, LLC	10,144	$59

Increased Positions (50)

BRIDGEWAY CAPITAL MANAGEMENT, LLC

Value ($000) $4,602 (+99.9%) Shares 773,485 (+78.4%)

Round Rock Advisors, LLC

Value ($000) $570 (+72.9%) Shares 105,042 (+60.6%)

RITHOLTZ WEALTH MANAGEMENT

Value ($000) $4,129 (+65.2%) Shares 694,001 (+47.4%)

State of Wyoming

Value ($000) $316 (+367.6%) Shares 53,155 (+317.3%)

Baron Wealth Management LLC

Value ($000) $211 (+82.2%) Shares 35,392 (+62.6%)

O'SHAUGHNESSY ASSET MANAGEMENT, LLC

Value ($000) $6,666 (+51.6%) Shares 1,120,329 (+35.3%)

D'Orazio & Associates, Inc.

Value ($000) $296 (+74.8%) Shares 49,807 (+56.0%)

WINTON GROUP Ltd

Value ($000) $578 (+77.5%) Shares 97,159 (+58.4%)

AQR CAPITAL MANAGEMENT LLC

Value ($000) $3,966 (+471.6%) Shares 666,605 (+410.1%)

Empowered Funds, LLC

Value ($000) $1,108 (+74.5%) Shares 186,185 (+55.7%)

GOLDMAN SACHS GROUP INC

Value ($000) $4,724 (+279.2%) Shares 793,962 (+238.4%)

AMERICAN CENTURY COMPANIES INC

Value ($000) $9,818 (+24.7%) Shares 1,650,137 (+11.3%)

TWO SIGMA INVESTMENTS, LP

Value ($000) $966 (+224.1%) Shares 162,351 (+189.3%)

STATE OF WISCONSIN INVESTMENT BOARD

Value ($000) $796 (+176.0%) Shares 133,774 (+146.3%)

STATE STREET CORP

Value ($000) $5,219 (+31.3%) Shares 877,077 (+17.2%)

SEI INVESTMENTS CO

Value ($000) $2,558 (+38.7%) Shares 429,925 (+23.8%)

VANGUARD GROUP INC

Value ($000) $22,597 (+15.3%) Shares 3,797,748 (+2.9%)

ARROWSTREET CAPITAL, LIMITED PARTNERSHIP

Value ($000) $3,260 (+32.1%) Shares 547,853 (+17.9%)

NORTHERN TRUST CORP

Value ($000) $3,666 (+31.1%) Shares 616,197 (+17.0%)

PRUDENTIAL FINANCIAL INC

Value ($000) $1,705 (+45.3%) Shares 286,509 (+29.7%)

Institution	Prev Shares	Curr Shares	Change
BRIDGEWAY CAPITAL MANAGEMENT, LLC	433,561	773,485	+339,924 (+78.4%)
Round Rock Advisors, LLC	65,396	105,042	+39,646 (+60.6%)
RITHOLTZ WEALTH MANAGEMENT	470,767	694,001	+223,234 (+47.4%)
State of Wyoming	12,737	53,155	+40,418 (+317.3%)
Baron Wealth Management LLC	21,767	35,392	+13,625 (+62.6%)
O'SHAUGHNESSY ASSET MANAGEMENT, LLC	828,221	1,120,329	+292,108 (+35.3%)
D'Orazio & Associates, Inc.	31,933	49,807	+17,874 (+56.0%)
WINTON GROUP Ltd	61,324	97,159	+35,835 (+58.4%)
AQR CAPITAL MANAGEMENT LLC	130,672	666,605	+535,933 (+410.1%)
Empowered Funds, LLC	119,561	186,185	+66,624 (+55.7%)
GOLDMAN SACHS GROUP INC	234,617	793,962	+559,345 (+238.4%)
AMERICAN CENTURY COMPANIES INC	1,483,188	1,650,137	+166,949 (+11.3%)
TWO SIGMA INVESTMENTS, LP	56,126	162,351	+106,225 (+189.3%)
STATE OF WISCONSIN INVESTMENT BOARD	54,318	133,774	+79,456 (+146.3%)
STATE STREET CORP	748,658	877,077	+128,419 (+17.2%)
SEI INVESTMENTS CO	347,234	429,925	+82,691 (+23.8%)
VANGUARD GROUP INC	3,691,720	3,797,748	+106,028 (+2.9%)
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP	464,734	547,853	+83,119 (+17.9%)
NORTHERN TRUST CORP	526,736	616,197	+89,461 (+17.0%)
PRUDENTIAL FINANCIAL INC	220,944	286,509	+65,565 (+29.7%)

Decreased Positions (36)

Russell Investments Group, Ltd.

Value ($000) $1,497 (-70.8%) Shares 251,653 (-73.9%)

LOS ANGELES CAPITAL MANAGEMENT LLC

Value ($000) $809 (-44.4%) Shares 148,132 (-45.9%)

Headlands Technologies LLC

Value ($000) $95 (-38.6%) Shares 15,976 (-45.2%)

Universal- Beteiligungs- und Servicegesellschaft mbH

Value ($000) $234 (-77.8%) Shares 39,308 (-80.2%)

UBS Group AG

Value ($000) $758 (-62.1%) Shares 127,312 (-66.1%)

Connor, Clark & Lunn Investment Management Ltd.

Value ($000) $5,208 (+4.0%) Shares 875,301 (-7.2%)

D. E. Shaw & Co., Inc.

Value ($000) $2,251 (-15.0%) Shares 378,296 (-24.1%)

JANE STREET GROUP, LLC

Value ($000) $216 (-70.6%) Shares 36,362 (-73.8%)

MILLENNIUM MANAGEMENT LLC

Value ($000) $99 (-82.4%) Shares 16,614 (-84.3%)

Qube Research & Technologies Ltd

Value ($000) $664 (-19.6%) Shares 111,520 (-28.3%)

MORGAN STANLEY

Value ($000) $1,944 (-3.2%) Shares 326,774 (-13.6%)

Metis Global Partners, LLC

Value ($000) $253 (-14.5%) Shares 42,586 (-23.7%)

PRELUDE CAPITAL MANAGEMENT, LLC

Value ($000) $191 (-6.2%) Shares 32,148 (-16.3%)

RENAISSANCE TECHNOLOGIES LLC

Value ($000) $12,637 (+10.6%) Shares 2,123,813 (-1.3%)

STRS OHIO

Value ($000) $591 (-10.8%) Shares 99,400 (-20.4%)

MACKENZIE FINANCIAL CORP

Value ($000) $966 (+3.8%) Shares 160,973 (-8.1%)

LPL Financial LLC

Value ($000) $241 (-11.7%) Shares 40,442 (-21.2%)

ROYCE & ASSOCIATES LP

Value ($000) $71 (-28.7%) Shares 11,914 (-36.4%)

Prospera Financial Services Inc

Value ($000) $1,104 (+9.6%) Shares 185,496 (-2.2%)

OSAIC HOLDINGS, INC.

Value ($000) $72 (-24.6%) Shares 12,169 (-33.4%)

Institution	Prev Shares	Curr Shares	Change
Russell Investments Group, Ltd.	964,693	251,653	-713,040 (-73.9%)
LOS ANGELES CAPITAL MANAGEMENT LLC	274,050	148,132	-125,918 (-45.9%)
Headlands Technologies LLC	29,174	15,976	-13,198 (-45.2%)
Universal- Beteiligungs- und Servicegesellschaft mbH	198,508	39,308	-159,200 (-80.2%)
UBS Group AG	376,091	127,312	-248,779 (-66.1%)
Connor, Clark & Lunn Investment Management Ltd.	943,472	875,301	-68,171 (-7.2%)
D. E. Shaw & Co., Inc.	498,598	378,296	-120,302 (-24.1%)
JANE STREET GROUP, LLC	138,542	36,362	-102,180 (-73.8%)
MILLENNIUM MANAGEMENT LLC	105,633	16,614	-89,019 (-84.3%)
Qube Research & Technologies Ltd	155,516	111,520	-43,996 (-28.3%)
MORGAN STANLEY	378,082	326,774	-51,308 (-13.6%)
Metis Global Partners, LLC	55,798	42,586	-13,212 (-23.7%)
PRELUDE CAPITAL MANAGEMENT, LLC	38,422	32,148	-6,274 (-16.3%)
RENAISSANCE TECHNOLOGIES LLC	2,151,213	2,123,813	-27,400 (-1.3%)
STRS OHIO	124,900	99,400	-25,500 (-20.4%)
MACKENZIE FINANCIAL CORP	175,210	160,973	-14,237 (-8.1%)
LPL Financial LLC	51,303	40,442	-10,861 (-21.2%)
ROYCE & ASSOCIATES LP	18,725	11,914	-6,811 (-36.4%)
Prospera Financial Services Inc	189,619	185,496	-4,123 (-2.2%)
OSAIC HOLDINGS, INC.	18,263	12,169	-6,094 (-33.4%)

Exited Positions (14)

SHERBROOKE PARK ADVISERS LLC

Value ($000) $162 Shares 30,527

TANG CAPITAL MANAGEMENT LLC

Value ($000) $1,062 Shares 200,000

Hillsdale Investment Management Inc.

Value ($000) $413 Shares 77,800

MARSHALL WACE, LLP

Value ($000) $2,961 Shares 557,548

Graham Capital Management, L.P.

Value ($000) $280 Shares 52,708

XTX Topco Ltd

Value ($000) $136 Shares 25,524

WELLINGTON MANAGEMENT GROUP LLP

Value ($000) $794 Shares 149,552

Assenagon Asset Management S.A.

Value ($000) $388 Shares 72,979

MACQUARIE GROUP LTD

Value ($000) $325 Shares 61,255

Sanctuary Advisors, LLC

Value ($000) $127 Shares 23,866

DEUTSCHE BANK AG\

Value ($000) $163 Shares 30,743

Squarepoint Ops LLC

Value ($000) $113 Shares 21,334

Luminist Capital LLC

Value ($000) $1 Shares 250

Atlantic Union Bankshares Corp

Value ($000) $1 Shares 150

Institution	Prev Shares	Prev Value ($000)
SHERBROOKE PARK ADVISERS LLC	30,527	$162
TANG CAPITAL MANAGEMENT LLC	200,000	$1,062
Hillsdale Investment Management Inc.	77,800	$413
MARSHALL WACE, LLP	557,548	$2,961
Graham Capital Management, L.P.	52,708	$280
XTX Topco Ltd	25,524	$136
WELLINGTON MANAGEMENT GROUP LLP	149,552	$794
Assenagon Asset Management S.A.	72,979	$388
MACQUARIE GROUP LTD	61,255	$325
Sanctuary Advisors, LLC	23,866	$127
DEUTSCHE BANK AG\	30,743	$163
Squarepoint Ops LLC	21,334	$113
Luminist Capital LLC	250	$1
Atlantic Union Bankshares Corp	150	$1