Location: Zurich, Switzerland
CIK: 0001674546 · Show all filings
Period: Q1 2023 (← Previous) (Next →)
Filing Date: May 15, 2023
Total Value: $6.891B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| VRTX | VERTEX PHARMACEUTICALS INC | 1,145,695 | $361M | 5.2% | $197.89 | +51.6% | COM | 92532F100 |
| IONS | IONIS PHARMACEUTICALS INC | 9,511,900 | $340M | 4.9% | $61.40 | -38.8% | COM | 462222100 |
| ARGX | ARGENX SE | 886,928 | $330M | 4.8% | $147.55 | — | SPONSORED ADR | 04016X101 |
| NBIX | NEUROCRINE BIOSCIENCES INC | 2,613,300 | $265M | 3.8% | $83.66 | +24.4% | COM | 64125C109 |
| ISRG | INTUITIVE SURGICAL INC | 968,786 | $247M | 3.6% | $268.75 | -8.3% | COM NEW | 46120E602 |
| MRNA | MODERNA INC | 1,551,706 | $238M | 3.5% | $23.27 | +608.9% | COM | 60770K107 |
| INCY | INCYTE CORP | 2,840,500 | $205M | 3.0% | $80.18 | -2.4% | COM | 45337C102 |
| — | INTRA-CELLULAR THERAPIES INC | 3,268,000 | $177M | 2.6% | $14.96 | — | COM | 46116X101 |
| ALNY | ALNYLAM PHARMACEUTICALS INC | 883,250 | $177M | 2.6% | $81.47 | +158.0% | COM | 02043Q107 |
| BSX | BOSTON SCIENTIFIC CORP | 3,439,579 | $172M | 2.5% | $36.97 | +27.5% | COM | 101137107 |
| ABT | ABBOTT LABS | 1,646,916 | $167M | 2.4% | $72.85 | +37.3% | COM | 002824100 |
| SYK | STRYKER CORPORATION | 484,774 | $138M | 2.0% | $184.08 | +40.0% | COM | 863667101 |
| — | SAGE THERAPEUTICS INC | 3,090,000 | $130M | 1.9% | $102.61 | — | COM | 78667J108 |
| — | AXONICS INC | 1,911,861 | $104M | 1.5% | $51.28 | — | COM | 05465P101 |
| PODD | INSULET CORP | 323,594 | $103M | 1.5% | $212.68 | +39.4% | COM | 45784P101 |
| RVMD | REVOLUTION MEDICINES INC | 4,747,900 | $103M | 1.5% | $30.94 | -20.4% | COM | 76155X100 |
| MDT | MEDTRONIC PLC | 1,229,235 | $99.1M | 1.4% | $82.01 | -9.1% | SHS | G5960L103 |
| AGIO | AGIOS PHARMACEUTICALS INC | 4,013,500 | $92.19M | 1.3% | $50.16 | -47.0% | COM | 00847X104 |
| UNH | UNITEDHEALTH GROUP INC | 194,811 | $92.07M | 1.3% | $216.29 | +111.4% | COM | 91324P102 |
| SRPT | SAREPTA THERAPEUTICS INC | 646,614 | $89.12M | 1.3% | $78.79 | +64.6% | COM | 803607100 |
| INSP | INSPIRE MED SYS INC | 377,068 | $88.26M | 1.3% | $115.41 | +119.0% | COM | 457730109 |
| DXCM | DEXCOM INC | 755,079 | $87.73M | 1.3% | $89.53 | +25.0% | COM | 252131107 |
| BDX | BECTON DICKINSON & CO | 348,043 | $86.15M | 1.3% | $212.26 | +9.4% | COM | 075887109 |
| EW | EDWARDS LIFESCIENCES CORP | 1,040,669 | $86.09M | 1.2% | $72.79 | +8.0% | COM | 28176E108 |
| DHR | DANAHER CORPORATION | 337,391 | $85.04M | 1.2% | $150.04 | +49.3% | COM | 235851102 |
| JAZZ | JAZZ PHARMACEUTICALS PLC | 569,857 | $83.39M | 1.2% | $147.29 | +0.4% | SHS USD | G50871105 |
| EXAS | EXACT SCIENCES CORP | 1,225,042 | $83.07M | 1.2% | $70.40 | -8.7% | COM | 30063P105 |
| PACB | PACIFIC BIOSCIENCES CALIF IN | 7,026,106 | $81.36M | 1.2% | $8.93 | +11.3% | COM | 69404D108 |
| HCA | HCA HEALTHCARE INC | 303,786 | $80.1M | 1.2% | $134.82 | +84.0% | COM | 40412C101 |
| OPCH | OPTION CARE HEALTH INC | 2,442,185 | $77.59M | 1.1% | $21.26 | +40.9% | COM NEW | 68404L201 |
| APLS | APELLIS PHARMACEUTICALS INC | 1,109,382 | $73.17M | 1.1% | $42.80 | +34.8% | COM | 03753U106 |
| TNDM | TANDEM DIABETES CARE INC | 1,793,763 | $72.84M | 1.1% | $76.85 | -46.1% | COM NEW | 875372203 |
| EVH | EVOLENT HEALTH INC | 2,191,147 | $71.1M | 1.0% | $14.79 | +113.8% | CL A | 30050B101 |
| MGNX | MACROGENICS INC | 9,609,913 | $68.9M | 1.0% | $16.65 | -63.8% | COM | 556099109 |
| RLAY | RELAY THERAPEUTICS INC | 4,172,600 | $68.72M | 1.0% | $35.33 | -49.3% | COM | 75943R102 |
| PEN | PENUMBRA INC | 238,172 | $66.38M | 1.0% | $199.63 | +27.9% | COM | 70975L107 |
| CLDX | CELLDEX THERAPEUTICS INC | 1,800,000 | $64.76M | 0.9% | $29.83 | +44.7% | COM NEW | 15117B202 |
| CRL | CHARLES RIV LABS INTL INC | 302,446 | $61.04M | 0.9% | $237.73 | -4.7% | COM | 159864107 |
| — | SHOCKWAVE MED INC | 281,376 | $61.01M | 0.9% | $80.46 | — | COM | 82489T104 |
| — | ACCOLADE INC | 4,041,801 | $58.12M | 0.8% | $30.65 | — | COM | 00437E102 |
| ARVN | ARVINAS INC | 2,127,000 | $58.11M | 0.8% | $34.23 | -7.7% | COM | 04335A105 |
| ALGN | ALIGN TECHNOLOGY INC | 171,140 | $57.18M | 0.8% | $316.81 | -6.9% | COM | 016255101 |
| INSM | INSMED INC | 3,293,102 | $56.15M | 0.8% | $28.84 | -32.6% | COM PAR $.01 | 457669307 |
| IDXX | IDEXX LABS INC | 110,928 | $55.47M | 0.8% | $361.71 | +32.3% | COM | 45168D104 |
| BIO | BIO RAD LABS INC | 113,739 | $54.48M | 0.8% | $506.90 | -7.7% | CL A | 090572207 |
| — | OUTSET MED INC | 2,906,759 | $53.48M | 0.8% | $38.88 | — | COM | 690145107 |
| EXEL | EXELIXIS INC | 2,609,000 | $50.64M | 0.7% | $20.80 | -16.3% | COM | 30161Q104 |
| TMO | THERMO FISHER SCIENTIFIC INC | 86,333 | $49.76M | 0.7% | $459.74 | +21.5% | COM | 883556102 |
| VEEV | VEEVA SYS INC | 262,985 | $48.33M | 0.7% | $197.72 | -13.7% | CL A COM | 922475108 |
| TMDX | TRANSMEDICS GROUP INC | 629,484 | $47.67M | 0.7% | $22.15 | +212.1% | COM | 89377M109 |
| ELV | ELEVANCE HEALTH INC | 92,970 | $42.75M | 0.6% | $247.96 | +83.6% | COM | 036752103 |
| — | SILK RD MED INC | 1,069,739 | $41.86M | 0.6% | $47.93 | — | COM | 82710M100 |
| CRSP | CRISPR THERAPEUTICS AG | 899,800 | $40.7M | 0.6% | $55.85 | -13.0% | NAMEN AKT | H17182108 |
| — | AMEDISYS INC | 542,616 | $39.91M | 0.6% | $153.20 | — | COM | 023436108 |
| MOH | MOLINA HEALTHCARE INC | 142,609 | $38.15M | 0.6% | $211.66 | +35.8% | COM | 60855R100 |
| GMED | GLOBUS MED INC | 647,645 | $36.68M | 0.5% | $54.84 | +16.9% | CL A | 379577208 |
| CNC | CENTENE CORP DEL | 549,341 | $34.72M | 0.5% | $64.19 | +10.6% | COM | 15135B101 |
| IQV | IQVIA HLDGS INC | 172,478 | $34.3M | 0.5% | $227.21 | -5.9% | COM | 46266C105 |
| ZBH | ZIMMER BIOMET HOLDINGS INC | 265,270 | $34.27M | 0.5% | $118.21 | +3.5% | COM | 98956P102 |
| HUM | HUMANA INC | 68,570 | $33.29M | 0.5% | $301.11 | +58.9% | COM | 444859102 |
| CDNA | CAREDX INC | 3,439,091 | $31.43M | 0.5% | $37.26 | -65.7% | COM | 14167L103 |
| — | COOPER COS INC | 81,313 | $30.36M | 0.4% | $339.12 | — | COM NEW | 216648402 |
| PFE | PFIZER INC | 740,695 | $30.22M | 0.4% | $41.63 | -12.2% | COM | 717081103 |
| HALO | HALOZYME THERAPEUTICS INC | 742,400 | $28.35M | 0.4% | $19.03 | +146.4% | COM | 40637H109 |
| PRVA | PRIVIA HEALTH GROUP INC | 1,002,644 | $27.68M | 0.4% | $32.19 | -18.0% | COM | 74276R102 |
| FATE | FATE THERAPEUTICS INC | 4,855,779 | $27.68M | 0.4% | $40.00 | -84.9% | COM | 31189P102 |
| AXSM | AXSOME THERAPEUTICS INC | 441,350 | $27.22M | 0.4% | $45.50 | +44.4% | COM | 05464T104 |
| OMCL | OMNICELL COM | 463,367 | $27.19M | 0.4% | $83.27 | -33.8% | COM | 68213N109 |
| ATRC | ATRICURE INC | 647,222 | $26.83M | 0.4% | $52.86 | -21.5% | COM | 04963C209 |
| BNTX | BIONTECH SE | 196,480 | $24.48M | 0.4% | $194.88 | — | SPONSORED ADS | 09075V102 |
| LEGN | LEGEND BIOTECH CORP | 507,254 | $24.46M | 0.4% | $41.55 | — | SPONSORED ADS | 52490G102 |
| HCM | HUTCHMED CHINA LTD | 1,826,970 | $23.79M | 0.3% | $24.55 | — | SPONSORED ADS | 44842L103 |
| — | ESSA PHARMA INC | 7,898,583 | $23.46M | 0.3% | $12.40 | — | COM NEW | 29668H708 |
| HOLX | HOLOGIC INC | 290,136 | $23.41M | 0.3% | $59.24 | +35.9% | COM | 436440101 |
| ILMN | ILLUMINA INC | 99,257 | $23.08M | 0.3% | $282.52 | -27.6% | COM | 452327109 |
| CSTL | CASTLE BIOSCIENCES INC | 948,878 | $21.56M | 0.3% | $34.92 | -30.0% | COM | 14843C105 |
| RMD | RESMED INC | 98,275 | $21.52M | 0.3% | $131.86 | +60.2% | COM | 761152107 |
| BEAM | BEAM THERAPEUTICS INC | 695,421 | $21.29M | 0.3% | $60.73 | -35.0% | COM | 07373V105 |
| PRCT | PROCEPT BIOROBOTICS CORP | 741,517 | $21.06M | 0.3% | $36.30 | -2.8% | COM | 74276L105 |
| PHR | PHREESIA INC | 638,653 | $20.62M | 0.3% | $34.59 | +1.7% | COM | 71944F106 |
| HRMY | HARMONY BIOSCIENCES HLDGS IN | 598,046 | $19.53M | 0.3% | $42.78 | +6.4% | COM | 413197104 |
| WVE | WAVE LIFE SCIENCES LTD | 4,494,458 | $19.46M | 0.3% | $16.12 | -71.6% | SHS | Y95308105 |
| TXG | 10X GENOMICS INC | 324,746 | $18.12M | 0.3% | $86.25 | -45.9% | CL A COM | 88025U109 |
| — | MERSANA THERAPEUTICS INC | 4,299,619 | $17.67M | 0.3% | $17.62 | — | COM | 59045L106 |
| SRRK | SCHOLAR ROCK HLDG CORP | 2,140,025 | $17.12M | 0.2% | $17.34 | -41.5% | COM | 80706P103 |
| — | GENERATION BIO CO | 3,620,280 | $15.57M | 0.2% | $18.19 | — | COM | 37148K100 |
| DOCS | DOXIMITY INC | 448,579 | $14.52M | 0.2% | $36.02 | -7.9% | CL A | 26622P107 |
| CI | THE CIGNA GROUP | 53,476 | $13.66M | 0.2% | $175.02 | +57.8% | COM | 125523100 |
| NTRA | NATERA INC | 232,775 | $12.92M | 0.2% | $42.92 | +11.8% | COM | 632307104 |
| REGN | REGENERON PHARMACEUTICALS | 15,316 | $12.58M | 0.2% | $480.23 | +56.2% | COM | 75886F107 |
| ONC | BEIGENE LTD | 58,235 | $12.55M | 0.2% | $209.58 | — | SPONSORED ADR | 07725L102 |
| TDOC | TELADOC HEALTH INC | 432,721 | $11.21M | 0.2% | $109.52 | -75.6% | COM | 87918A105 |
| BAX | BAXTER INTL INC | 273,614 | $11.1M | 0.2% | $68.53 | -42.5% | COM | 071813109 |
| BDTX | BLACK DIAMOND THERAPEUTICS I | 5,395,839 | $10.2M | 0.1% | $16.63 | -86.2% | COM | 09203E105 |
| AMGN | AMGEN INC | 38,367 | $9.275M | 0.1% | $182.53 | +22.7% | COM | 031162100 |
| GILD | GILEAD SCIENCES INC | 100,356 | $8.327M | 0.1% | $59.56 | +25.4% | COM | 375558103 |
| — | NEVRO CORP | 218,573 | $7.901M | 0.1% | $97.81 | — | COM | 64157F103 |
| BIIB | BIOGEN INC | 24,704 | $6.868M | 0.1% | $248.12 | +11.5% | COM | 09062X103 |
| ESPR | ESPERION THERAPEUTICS INC NE | 4,208,264 | $6.691M | 0.1% | $43.86 | -88.2% | COM | 29664W105 |
| RDY | DR REDDYS LABS LTD | 103,500 | $5.892M | 0.1% | $51.49 | — | ADR | 256135203 |
| — | OLINK HLDG AB | 239,624 | $5.399M | 0.1% | $32.23 | — | SPONSORED ADS | 680710100 |
| ZLAB | ZAI LAB LTD | 159,400 | $5.302M | 0.1% | $33.06 | — | ADR | 98887Q104 |
| — | VERONA PHARMA PLC | 262,683 | $5.275M | 0.1% | $20.08 | — | SPONSORED ADS | 925050106 |
| AZN | ASTRAZENECA PLC | 71,600 | $4.97M | 0.1% | $63.68 | — | SPONSORED ADR | 046353108 |
| BMRN | BIOMARIN PHARMACEUTICAL INC | 48,445 | $4.711M | 0.1% | $82.93 | +25.0% | COM | 09061G101 |
| — | SEAGEN INC | 22,700 | $4.596M | 0.1% | $170.06 | — | COM | 81181C104 |
| SUPN | SUPERNUS PHARMACEUTICALS INC | 122,881 | $4.452M | 0.1% | $31.58 | +21.8% | COM | 868459108 |
| — | MOLECULAR TEMPLATES INC | 11,230,003 | $4.266M | 0.1% | $10.65 | — | COM | 608550109 |
| LLY | LILLY ELI & CO | 10,764 | $3.697M | 0.1% | $311.91 | +5.8% | COM | 532457108 |
| JNJ | JOHNSON & JOHNSON | 22,905 | $3.55M | 0.1% | $138.98 | +6.4% | COM | 478160104 |
| — | AMERICAN WELL CORP | 1,462,178 | $3.451M | 0.1% | $19.32 | — | CL A | 03044L105 |
| ABBV | ABBVIE INC | 17,176 | $2.737M | 0.0% | $125.65 | +9.9% | COM | 00287Y109 |
| COR | AMERISOURCEBERGEN CORP | 15,910 | $2.547M | 0.0% | $142.78 | +8.3% | COM | 03073E105 |
| SGHT | SIGHT SCIENCES INC | 286,284 | $2.502M | 0.0% | $32.87 | -66.2% | COM | 82657M105 |
| KOS | KOSMOS ENERGY LTD | 318,300 | $2.368M | 0.0% | $3.22 | +127.4% | COM | 500688106 |
| GH | GUARDANT HEALTH INC | 82,197 | $1.927M | 0.0% | $73.85 | -61.3% | COM | 40131M109 |
| CYTK | CYTOKINETICS INC | 54,200 | $1.907M | 0.0% | $36.38 | +12.1% | COM NEW | 23282W605 |
| ALKS | ALKERMES PLC | 64,200 | $1.81M | 0.0% | $25.41 | +7.2% | SHS | G01767105 |
| CVS | CVS HEALTH CORP | 22,814 | $1.695M | 0.0% | $65.49 | +14.8% | COM | 126650100 |
| — | LABORATORY CORP AMER HLDGS | 6,988 | $1.603M | 0.0% | $233.68 | — | COM NEW | 50540R409 |
| KRYS | KRYSTAL BIOTECH INC | 18,300 | $1.465M | 0.0% | $61.97 | +26.8% | COM | 501147102 |
| BBIO | BRIDGEBIO PHARMA INC | 82,600 | $1.37M | 0.0% | $11.66 | 0.0% | COM | 10806X102 |
| — | KARUNA THERAPEUTICS INC | 7,300 | $1.326M | 0.0% | $196.50 | — | COM | 48576A100 |
| — | IVERIC BIO INC | 52,900 | $1.287M | 0.0% | $22.02 | — | COM | 46583P102 |
| VRDN | VIRIDIAN THERAPEUTICS INC | 46,100 | $1.173M | 0.0% | $13.44 | +138.6% | COM | 92790C104 |
| BCYC | BICYCLE THERAPEUTICS PLC | 53,200 | $1.132M | 0.0% | $26.91 | — | SPONSORED ADS | 088786108 |
| GDX | VANECK ETF TRUST | 33,000 | $1.068M | 0.0% | $34.23 | — | GOLD MINERS ETF | 92189F106 |
| — | 89BIO INC | 67,000 | $1.02M | 0.0% | $15.23 | — | COM | 282559103 |
| — | AKERO THERAPEUTICS INC | 26,100 | $999K | 0.0% | $34.55 | — | COM | 00973Y108 |
| MCK | MCKESSON CORP | 2,739 | $975K | 0.0% | $190.47 | +87.0% | COM | 58155Q103 |
| VTYX | VENTYX BIOSCIENCES INC | 25,500 | $854K | 0.0% | $38.88 | 0.0% | COM | 92332V107 |
| — | MERUS N V | 45,700 | $841K | 0.0% | $18.01 | — | COM | N5749R100 |
| CAH | CARDINAL HEALTH INC | 10,600 | $800K | 0.0% | $70.49 | +1.4% | COM | 14149Y108 |
| MRK | MERCK & CO INC | 7,075 | $753K | 0.0% | $84.42 | +16.9% | COM | 58933Y105 |
| SPY | SPDR S&P 500 ETF TR | 1,800 | $737K | 0.0% | $357.22 | — | TR UNIT | 78462F103 |
| DNLI | DENALI THERAPEUTICS INC | 31,000 | $714K | 0.0% | $32.51 | -15.3% | COM | 24823R105 |
| XNCR | XENCOR INC | 25,400 | $708K | 0.0% | $43.40 | -29.0% | COM | 98401F105 |
| RCKT | ROCKET PHARMACEUTICALS INC | 36,600 | $627K | 0.0% | $18.42 | +6.3% | COM | 77313F106 |
| GOOG | ALPHABET INC | 6,000 | $624K | 0.0% | $111.55 | -14.1% | CAP STK CL C | 02079K107 |
| — | INHIBRX INC | 29,700 | $560K | 0.0% | $32.31 | — | COM | 45720L107 |
| ARWR | ARROWHEAD PHARMACEUTICALS IN | 21,300 | $541K | 0.0% | $33.13 | -5.1% | COM | 04280A100 |
| SEER | SEER INC | 136,133 | $525K | 0.0% | $57.71 | -92.0% | COM CL A | 81578P106 |
| XOP | SPDR SER TR | 3,900 | $498K | 0.0% | $124.62 | — | S&P OILGAS EXP | 78468R556 |
| ZTS | ZOETIS INC | 1,373 | $229K | 0.0% | $159.02 | 0.0% | CL A | 98978V103 |
| MCHI | ISHARES TR | 4,100 | $205K | 0.0% | $55.85 | — | MSCI CHINA ETF | 46429B671 |
| GDXJ | VANECK ETF TRUST | 5,000 | $198K | 0.0% | $32.00 | — | JUNIOR GOLD MINE | 92189F791 |
| OPTEY | OPTHEA LTD | 47,000 | $186K | 0.0% | $11.36 | — | SPONSORED ADS | 68386J208 |
| IPGP | IPG PHOTONICS CORP | 1,050 | $129K | 0.0% | $143.92 | -19.5% | COM | 44980X109 |
| DGX | QUEST DIAGNOSTICS INC | 870 | $123K | 0.0% | $135.20 | 0.0% | COM | 74834L100 |
| BMY | BRISTOL-MYERS SQUIBB CO | 1,496 | $104K | 0.0% | $62.46 | -1.5% | COM | 110122108 |
| HSIC | HENRY SCHEIN INC | 1,043 | $85,046 | 0.0% | $81.49 | 0.0% | COM | 806407102 |
| TSM | TAIWAN SEMICONDUCTOR MFG LTD | 770 | $71,625 | 0.0% | $68.83 | — | SPONSORED ADS | 874039100 |
| JMIA | JUMIA TECHNOLOGIES AG | 18,000 | $59,220 | 0.0% | $35.44 | — | SPONSORED ADS | 48138M105 |
| ASR | GRUPO AEROPORTUARIO DEL SURE | 135 | $41,373 | 0.0% | $207.41 | — | SPON ADR SER B | 40051E202 |
| — | KEZAR LIFE SCIENCES INC | 10,000 | $31,300 | 0.0% | $6.29 | — | COM | 49372L100 |
| EQIX | EQUINIX INC | 40 | $28,842 | 0.0% | $738.08 | -10.3% | COM | 29444U700 |
| EVTC | EVERTEC INC | 739 | $24,941 | 0.0% | $45.34 | -23.6% | COM | 30040P103 |
| UMC | UNITED MICROELECTRONICS CORP | 2,698 | $23,634 | 0.0% | $5.56 | — | SPON ADR NEW | 910873405 |
| INFY | INFOSYS LTD | 1,130 | $19,707 | 0.0% | $25.66 | — | SPONSORED ADR | 456788108 |