Location: Zurich, Switzerland
CIK: 0001674546 · Show all filings
Period: Q2 2023 (← Previous) (Next →)
Filing Date: Aug 14, 2023
Total Value: $7.01B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| VRTX | VERTEX PHARMACEUTICALS INC | 1,097,166 | $386M | 5.5% | $197.89 | +70.3% | COM | 92532F100 |
| IONS | IONIS PHARMACEUTICALS INC | 9,380,300 | $385M | 5.5% | $61.40 | -37.4% | COM | 462222100 |
| ARGX | ARGENX SE | 923,284 | $360M | 5.1% | $157.09 | — | SPONSORED ADR | 04016X101 |
| ISRG | INTUITIVE SURGICAL INC | 842,224 | $288M | 4.1% | $268.75 | +12.6% | COM NEW | 46120E602 |
| NBIX | NEUROCRINE BIOSCIENCES INC | 2,612,800 | $246M | 3.5% | $83.66 | +16.8% | COM | 64125C109 |
| — | INTRA-CELLULAR THERAPIES INC | 3,201,800 | $203M | 2.9% | $14.96 | — | COM | 46116X101 |
| MRNA | MODERNA INC | 1,525,059 | $185M | 2.6% | $23.27 | +473.2% | COM | 60770K107 |
| ABT | ABBOTT LABS | 1,646,501 | $180M | 2.6% | $72.85 | +39.3% | COM | 002824100 |
| ALNY | ALNYLAM PHARMACEUTICALS INC | 899,650 | $171M | 2.4% | $83.60 | +137.1% | COM | 02043Q107 |
| INCY | INCYTE CORP | 2,640,765 | $164M | 2.3% | $80.18 | -16.6% | COM | 45337C102 |
| — | SAGE THERAPEUTICS INC | 3,114,375 | $146M | 2.1% | $102.61 | — | COM | 78667J108 |
| SYK | STRYKER CORPORATION | 476,946 | $146M | 2.1% | $184.08 | +52.8% | COM | 863667101 |
| BSX | BOSTON SCIENTIFIC CORP | 2,661,452 | $144M | 2.1% | $36.97 | +41.3% | COM | 101137107 |
| RVMD | REVOLUTION MEDICINES INC | 4,746,000 | $127M | 1.8% | $30.94 | -20.7% | COM | 76155X100 |
| MDT | MEDTRONIC PLC | 1,410,492 | $124M | 1.8% | $81.67 | -2.8% | SHS | G5960L103 |
| INSP | INSPIRE MED SYS INC | 357,020 | $116M | 1.7% | $115.41 | +147.6% | COM | 457730109 |
| AGIO | AGIOS PHARMACEUTICALS INC | 4,013,500 | $114M | 1.6% | $50.16 | -50.4% | COM | 00847X104 |
| — | AXONICS INC | 2,223,418 | $112M | 1.6% | $51.16 | — | COM | 05465P101 |
| EVH | EVOLENT HEALTH INC | 3,448,322 | $104M | 1.5% | $21.19 | +52.6% | CL A | 30050B101 |
| UNH | UNITEDHEALTH GROUP INC | 210,127 | $101M | 1.4% | $234.41 | +98.3% | COM | 91324P102 |
| PACB | PACIFIC BIOSCIENCES CALIF IN | 7,542,829 | $100M | 1.4% | $9.15 | +32.8% | COM | 69404D108 |
| EW | EDWARDS LIFESCIENCES CORP | 1,038,092 | $97.92M | 1.4% | $72.79 | +19.4% | COM | 28176E108 |
| DXCM | DEXCOM INC | 761,716 | $97.89M | 1.4% | $89.53 | +35.1% | COM | 252131107 |
| EXAS | EXACT SCIENCES CORP | 1,006,772 | $94.54M | 1.3% | $70.40 | +10.8% | COM | 30063P105 |
| PODD | INSULET CORP | 323,594 | $93.31M | 1.3% | $212.68 | +42.8% | COM | 45784P101 |
| BDX | BECTON DICKINSON & CO | 337,723 | $89.16M | 1.3% | $212.26 | +14.0% | COM | 075887109 |
| PEN | PENUMBRA INC | 234,220 | $80.59M | 1.1% | $199.63 | +53.8% | COM | 70975L107 |
| — | SHOCKWAVE MED INC | 270,526 | $77.21M | 1.1% | $80.46 | — | COM | 82489T104 |
| OPCH | OPTION CARE HEALTH INC | 2,287,623 | $74.32M | 1.1% | $21.26 | +41.8% | COM NEW | 68404L201 |
| INSM | INSMED INC | 3,300,911 | $69.65M | 1.0% | $28.84 | -34.2% | COM PAR $.01 | 457669307 |
| — | OUTSET MED INC | 3,125,886 | $68.36M | 1.0% | $37.68 | — | COM | 690145107 |
| CRL | CHARLES RIV LABS INTL INC | 314,513 | $66.13M | 0.9% | $236.25 | -15.8% | COM | 159864107 |
| CLDX | CELLDEX THERAPEUTICS INC NEW | 1,800,000 | $61.07M | 0.9% | $29.83 | +13.0% | COM NEW | 15117B202 |
| — | ACCOLADE INC | 4,521,059 | $60.9M | 0.9% | $28.83 | — | COM | 00437E102 |
| ALGN | ALIGN TECHNOLOGY INC | 171,140 | $60.52M | 0.9% | $316.81 | +0.5% | COM | 016255101 |
| IDXX | IDEXX LABS INC | 114,441 | $57.48M | 0.8% | $365.32 | +31.2% | COM | 45168D104 |
| HUM | HUMANA INC | 127,373 | $56.95M | 0.8% | $387.46 | +26.0% | COM | 444859102 |
| VEEV | VEEVA SYS INC | 271,046 | $53.59M | 0.8% | $197.26 | -7.5% | CL A COM | 922475108 |
| ARVN | ARVINAS INC | 2,127,000 | $52.79M | 0.8% | $34.23 | -24.9% | COM | 04335A105 |
| RLAY | RELAY THERAPEUTICS INC | 4,170,800 | $52.39M | 0.7% | $35.33 | -64.8% | COM | 75943R102 |
| TMDX | TRANSMEDICS GROUP INC | 612,613 | $51.45M | 0.7% | $22.15 | +245.5% | COM | 89377M109 |
| MGNX | MACROGENICS INC | 9,609,913 | $51.41M | 0.7% | $16.65 | -63.0% | COM | 556099109 |
| TNDM | TANDEM DIABETES CARE INC | 2,092,934 | $51.36M | 0.7% | $70.46 | -54.3% | COM NEW | 875372203 |
| BIO | BIO RAD LABS INC | 134,533 | $51M | 0.7% | $491.45 | -17.2% | CL A | 090572207 |
| CRSP | CRISPR THERAPEUTICS AG | 899,300 | $50.49M | 0.7% | $55.85 | +1.6% | NAMEN AKT | H17182108 |
| TMO | THERMO FISHER SCIENTIFIC INC | 96,101 | $50.14M | 0.7% | $467.41 | +14.5% | COM | 883556102 |
| MOH | MOLINA HEALTHCARE INC | 164,338 | $49.51M | 0.7% | $221.68 | +29.7% | COM | 60855R100 |
| HCA | HCA HEALTHCARE INC | 160,515 | $48.71M | 0.7% | $134.82 | +101.8% | COM | 40412C101 |
| EXEL | EXELIXIS INC | 2,534,000 | $48.42M | 0.7% | $20.80 | -7.3% | COM | 30161Q104 |
| APLS | APELLIS PHARMACEUTICALS INC | 518,495 | $47.23M | 0.7% | $42.80 | +101.6% | COM | 03753U106 |
| ELV | ELEVANCE HEALTH INC | 102,453 | $45.52M | 0.6% | $265.98 | +66.4% | COM | 036752103 |
| LLY | LILLY ELI & CO | 95,155 | $44.63M | 0.6% | $400.21 | +2.8% | COM | 532457108 |
| DHR | DANAHER CORPORATION | 183,709 | $44.09M | 0.6% | $150.04 | +39.1% | COM | 235851102 |
| — | SILK RD MED INC | 1,356,763 | $44.08M | 0.6% | $44.67 | — | COM | 82710M100 |
| ZBH | ZIMMER BIOMET HOLDINGS INC | 284,835 | $41.47M | 0.6% | $119.20 | +11.3% | COM | 98956P102 |
| AXSM | AXSOME THERAPEUTICS INC | 574,363 | $41.27M | 0.6% | $52.05 | +41.7% | COM | 05464T104 |
| BDTX | BLACK DIAMOND THERAPEUTICS I | 8,135,839 | $41.09M | 0.6% | $11.71 | -82.6% | COM | 09203E105 |
| GMED | GLOBUS MED INC | 647,645 | $38.56M | 0.6% | $54.84 | +3.9% | CL A | 379577208 |
| ATRC | ATRICURE INC | 748,613 | $36.95M | 0.5% | $51.95 | -11.3% | COM | 04963C209 |
| IQV | IQVIA HLDGS INC | 162,120 | $36.44M | 0.5% | $227.21 | -11.6% | COM | 46266C105 |
| JAZZ | JAZZ PHARMACEUTICALS PLC | 288,779 | $35.8M | 0.5% | $147.29 | -8.7% | SHS USD | G50871105 |
| MRK | MERCK & CO INC | 306,694 | $35.39M | 0.5% | $104.01 | +0.4% | COM | 58933Y105 |
| — | COOPER COS INC | 86,567 | $33.19M | 0.5% | $341.81 | — | COM NEW | 216648402 |
| CDNA | CAREDX INC | 3,716,477 | $31.59M | 0.5% | $35.10 | -76.2% | COM | 14167L103 |
| BMRN | BIOMARIN PHARMACEUTICAL INC | 360,604 | $31.26M | 0.4% | $92.60 | +1.6% | COM | 09061G101 |
| PRVA | PRIVIA HEALTH GROUP INC | 1,122,644 | $29.31M | 0.4% | $31.57 | -16.3% | COM | 74276R102 |
| PRCT | PROCEPT BIOROBOTICS CORP | 741,517 | $26.21M | 0.4% | $36.30 | -8.9% | COM | 74276L105 |
| HOLX | HOLOGIC INC | 290,136 | $23.49M | 0.3% | $59.24 | +37.9% | COM | 436440101 |
| FATE | FATE THERAPEUTICS INC | 4,855,779 | $23.11M | 0.3% | $40.00 | -86.2% | COM | 31189P102 |
| SRPT | SAREPTA THERAPEUTICS INC | 200,220 | $22.93M | 0.3% | $78.79 | +63.5% | COM | 803607100 |
| BEAM | BEAM THERAPEUTICS INC | 695,421 | $22.2M | 0.3% | $60.73 | -46.6% | COM | 07373V105 |
| HCM | HUTCHMED CHINA LTD | 1,805,583 | $21.67M | 0.3% | $24.55 | — | SPONSORED ADS | 44842L103 |
| OMCL | OMNICELL COM | 293,345 | $21.61M | 0.3% | $83.27 | -19.0% | COM | 68213N109 |
| RMD | RESMED INC | 98,275 | $21.47M | 0.3% | $131.86 | +64.9% | COM | 761152107 |
| — | AMEDISYS INC | 234,318 | $21.43M | 0.3% | $153.20 | — | COM | 023436108 |
| — | ESSA PHARMA INC | 7,898,583 | $21.33M | 0.3% | $12.40 | — | COM NEW | 29668H708 |
| — | GENERATION BIO CO | 3,620,280 | $19.91M | 0.3% | $18.19 | — | COM | 37148K100 |
| PHR | PHREESIA INC | 638,653 | $19.8M | 0.3% | $34.59 | -9.5% | COM | 71944F106 |
| CNC | CENTENE CORP DEL | 292,527 | $19.73M | 0.3% | $64.19 | +3.9% | COM | 15135B101 |
| SUPN | SUPERNUS PHARMACEUTICALS INC | 650,256 | $19.55M | 0.3% | $34.35 | +1.9% | COM | 868459108 |
| LEGN | LEGEND BIOTECH CORP | 275,754 | $19.04M | 0.3% | $41.55 | — | SPONSORED ADS | 52490G102 |
| TXG | 10X GENOMICS INC | 324,746 | $18.13M | 0.3% | $86.25 | -37.2% | CL A COM | 88025U109 |
| — | MERSANA THERAPEUTICS INC | 5,219,425 | $17.17M | 0.2% | $15.10 | — | COM | 59045L106 |
| WVE | WAVE LIFE SCIENCES LTD | 4,494,458 | $16.36M | 0.2% | $16.12 | -74.9% | SHS | Y95308105 |
| SRRK | SCHOLAR ROCK HLDG CORP | 2,140,025 | $16.14M | 0.2% | $17.34 | -56.5% | COM | 80706P103 |
| ILMN | ILLUMINA INC | 84,026 | $15.75M | 0.2% | $282.52 | -28.4% | COM | 452327109 |
| CSTL | CASTLE BIOSCIENCES INC | 1,124,043 | $15.42M | 0.2% | $32.63 | -37.9% | COM | 14843C105 |
| DOCS | DOXIMITY INC | 448,579 | $15.26M | 0.2% | $36.02 | -7.6% | CL A | 26622P107 |
| CI | THE CIGNA GROUP | 50,399 | $14.14M | 0.2% | $175.02 | +41.7% | COM | 125523100 |
| — | VERONA PHARMA PLC | 572,315 | $12.1M | 0.2% | $20.65 | — | SPONSORED ADS | 925050106 |
| REGN | REGENERON PHARMACEUTICALS | 16,327 | $11.73M | 0.2% | $497.97 | +54.0% | COM | 75886F107 |
| — | POINT BIOPHARMA GLOBAL INC | 1,256,197 | $11.38M | 0.2% | $9.06 | — | COM | 730541109 |
| NTRA | NATERA INC | 232,775 | $11.33M | 0.2% | $42.92 | +18.9% | COM | 632307104 |
| TDOC | TELADOC HEALTH INC | 392,264 | $9.932M | 0.1% | $109.52 | -77.0% | COM | 87918A105 |
| BAX | BAXTER INTL INC | 213,434 | $9.724M | 0.1% | $68.53 | -40.5% | COM | 071813109 |
| GILD | GILEAD SCIENCES INC | 112,650 | $8.682M | 0.1% | $60.98 | +19.0% | COM | 375558103 |
| BIIB | BIOGEN INC | 25,598 | $7.292M | 0.1% | $249.86 | +19.2% | COM | 09062X103 |
| AZN | ASTRAZENECA PLC | 85,600 | $6.126M | 0.1% | $64.97 | — | SPONSORED ADR | 046353108 |
| AMGN | AMGEN INC | 27,310 | $6.063M | 0.1% | $182.53 | +17.0% | COM | 031162100 |
| ESPR | ESPERION THERAPEUTICS INC NE | 4,208,264 | $5.849M | 0.1% | $43.86 | -96.8% | COM | 29664W105 |
| RDY | DR REDDYS LABS LTD | 91,700 | $5.787M | 0.1% | $51.49 | — | ADR | 256135203 |
| — | NEVRO CORP | 218,573 | $5.556M | 0.1% | $97.81 | — | COM | 64157F103 |
| — | MOLECULAR TEMPLATES INC | 11,230,003 | $5.39M | 0.1% | $10.65 | — | COM | 608550109 |
| — | OLINK HLDG AB | 239,624 | $4.493M | 0.1% | $32.23 | — | SPONSORED ADS | 680710100 |
| — | SEAGEN INC | 22,000 | $4.234M | 0.1% | $170.06 | — | COM | 81181C104 |
| JNJ | JOHNSON & JOHNSON | 21,225 | $3.513M | 0.1% | $138.98 | +7.1% | COM | 478160104 |
| COR | AMERISOURCEBERGEN CORP | 15,910 | $3.062M | 0.0% | $142.78 | +18.4% | COM | 03073E105 |
| GH | GUARDANT HEALTH INC | 82,197 | $2.943M | 0.0% | $73.85 | -61.1% | COM | 40131M109 |
| ALKS | ALKERMES PLC | 81,700 | $2.557M | 0.0% | $26.45 | +14.5% | SHS | G01767105 |
| CVS | CVS HEALTH CORP | 35,314 | $2.441M | 0.0% | $65.07 | -1.2% | COM | 126650100 |
| SGHT | SIGHT SCIENCES INC | 286,284 | $2.37M | 0.0% | $32.87 | -72.6% | COM | 82657M105 |
| — | KARUNA THERAPEUTICS INC | 10,100 | $2.19M | 0.0% | $202.14 | — | COM | 48576A100 |
| KRYS | KRYSTAL BIOTECH INC | 18,000 | $2.113M | 0.0% | $61.97 | +64.8% | COM | 501147102 |
| — | AMERICAN WELL CORP | 953,613 | $2.003M | 0.0% | $19.32 | — | CL A | 03044L105 |
| KOS | KOSMOS ENERGY LTD | 318,300 | $1.907M | 0.0% | $3.22 | +102.2% | COM | 500688106 |
| ONC | BEIGENE LTD | 10,200 | $1.819M | 0.0% | $209.58 | — | SPONSORED ADR | 07725L102 |
| — | LABORATORY CORP AMER HLDGS | 6,988 | $1.686M | 0.0% | $233.68 | — | COM NEW | 50540R409 |
| BBIO | BRIDGEBIO PHARMA INC | 96,900 | $1.667M | 0.0% | $12.16 | +23.7% | COM | 10806X102 |
| MCK | MCKESSON CORP | 3,296 | $1.408M | 0.0% | $222.42 | +70.6% | COM | 58155Q103 |
| DNLI | DENALI THERAPEUTICS INC | 44,050 | $1.3M | 0.0% | $31.21 | -9.9% | COM | 24823R105 |
| PCVX | VAXCYTE INC | 26,000 | $1.298M | 0.0% | $47.40 | 0.0% | COM | 92243G108 |
| — | INHIBRX INC | 48,800 | $1.267M | 0.0% | $29.83 | — | COM | 45720L107 |
| — | AKERO THERAPEUTICS INC | 27,100 | $1.265M | 0.0% | $35.00 | — | COM | 00973Y108 |
| — | 89BIO INC | 65,200 | $1.236M | 0.0% | $15.23 | — | COM | 282559103 |
| CYTK | CYTOKINETICS INC | 37,100 | $1.21M | 0.0% | $36.38 | +1.7% | COM NEW | 23282W605 |
| — | MERUS N V | 44,500 | $1.172M | 0.0% | $18.01 | — | COM | N5749R100 |
| ZTS | ZOETIS INC | 6,496 | $1.119M | 0.0% | $166.19 | +1.2% | CL A | 98978V103 |
| RCKT | ROCKET PHARMACEUTICALS INC | 55,600 | $1.105M | 0.0% | $19.03 | +6.2% | COM | 77313F106 |
| VRDN | VIRIDIAN THERAPEUTICS INC | 44,400 | $1.056M | 0.0% | $13.44 | +90.9% | COM | 92790C104 |
| GDX | VANECK ETF TRUST | 33,000 | $994K | 0.0% | $34.23 | — | GOLD MINERS ETF | 92189F106 |
| XENE | XENON PHARMACEUTICALS INC | 23,900 | $920K | 0.0% | $39.75 | 0.0% | COM | 98420N105 |
| — | DICE THERAPEUTICS INC | 18,200 | $846K | 0.0% | $46.46 | — | COM | 23345J104 |
| ABBV | ABBVIE INC | 6,174 | $832K | 0.0% | $125.65 | +6.4% | COM | 00287Y109 |
| FDMT | 4D MOLECULAR THERAPEUTICS IN | 45,000 | $813K | 0.0% | $18.41 | 0.0% | COM | 35104E100 |
| VTYX | VENTYX BIOSCIENCES INC | 24,500 | $804K | 0.0% | $38.88 | -11.3% | COM | 92332V107 |
| SPY | SPDR S&P 500 ETF TR | 1,800 | $798K | 0.0% | $357.22 | — | TR UNIT | 78462F103 |
| ARWR | ARROWHEAD PHARMACEUTICALS IN | 20,700 | $738K | 0.0% | $33.13 | +4.1% | COM | 04280A100 |
| GOOG | ALPHABET INC | 6,000 | $726K | 0.0% | $111.55 | +3.0% | CAP STK CL C | 02079K107 |
| BCYC | BICYCLE THERAPEUTICS PLC | 25,000 | $638K | 0.0% | $26.91 | — | SPONSORED ADS | 088786108 |
| SEER | SEER INC | 136,133 | $581K | 0.0% | $57.71 | -93.2% | COM CL A | 81578P106 |
| — | GRACELL BIOTECHNOLOGIES INC | 145,646 | $555K | 0.0% | $3.81 | — | SPONSORED ADS | 38406L103 |
| VKTX | VIKING THERAPEUTICS INC | 33,000 | $535K | 0.0% | $20.95 | 0.0% | COM | 92686J106 |
| XOP | SPDR SER TR | 3,900 | $502K | 0.0% | $124.62 | — | S&P OILGAS EXP | 78468R556 |
| DGX | QUEST DIAGNOSTICS INC | 1,942 | $273K | 0.0% | $132.87 | -1.4% | COM | 74834L100 |
| MCHI | ISHARES TR | 4,100 | $183K | 0.0% | $55.85 | — | MSCI CHINA ETF | 46429B671 |
| GDXJ | VANECK ETF TRUST | 5,000 | $178K | 0.0% | $32.00 | — | JUNIOR GOLD MINE | 92189F791 |
| TSM | TAIWAN SEMICONDUCTOR MFG LTD | 1,089 | $110K | 0.0% | $78.23 | — | SPONSORED ADS | 874039100 |
| — | ABCAM PLC | 2,573 | $62,961 | 0.0% | $24.47 | — | ADS | 000380204 |
| JMIA | JUMIA TECHNOLOGIES AG | 18,000 | $61,560 | 0.0% | $35.44 | — | SPONSORED ADS | 48138M105 |
| THC | TENET HEALTHCARE CORP | 669 | $54,443 | 0.0% | $71.19 | 0.0% | COM NEW | 88033G407 |
| ASR | GRUPO AEROPORTUARIO DEL SURE | 135 | $37,488 | 0.0% | $207.41 | — | SPON ADR SER B | 40051E202 |
| EQIX | EQUINIX INC | 40 | $31,358 | 0.0% | $738.08 | -6.2% | COM | 29444U700 |
| EVTC | EVERTEC INC | 739 | $27,217 | 0.0% | $45.34 | -24.5% | COM | 30040P103 |
| — | KEZAR LIFE SCIENCES INC | 10,000 | $24,500 | 0.0% | $6.29 | — | COM | 49372L100 |
| UMC | UNITED MICROELECTRONICS CORP | 2,698 | $21,287 | 0.0% | $5.56 | — | SPON ADR NEW | 910873405 |
| INFY | INFOSYS LTD | 1,130 | $18,159 | 0.0% | $25.66 | — | SPONSORED ADR | 456788108 |