RA CAPITAL MANAGEMENT, L.P. Diversified Active

Location: Boston, MA

CIK: 0001346824 · Show all filings

Period: Q2 2026 (← Previous)

Filing Date: Aug 14, 2026

Total Value: $11.51B (100.0% shares, 0.0% debt)

Holdings (84)

New Positions (17)

ASND ASCENDIS PHARMA A/S 23.8%
Value $2.742B Shares 10,281,496 Est. Cost Unrealized
PBLS PARABILIS MEDICINES INC 6.9%
Value $792M Shares 28,933,371 Est. Cost Unrealized
COAG HEMAB THERAPEUTICS HOLDINGS 2.5%
Value $287M Shares 7,808,627 Est. Cost Unrealized
ABVX ABIVAX SA-ADR 1.3%
Value $151M Shares 1,132,557 Est. Cost Unrealized
ORKA ORUKA THERAPEUTICS INC 1.3%
Value $148M Shares 1,554,597 Est. Cost Unrealized
NTLA INTELLIA THERAPEUTICS INC 0.7%
Value $76.6M Shares 4,526,926 Est. Cost Unrealized
DFTX DEFINIUM THERAPEUTICS INC 0.6%
Value $70.56M Shares 1,500,000 Est. Cost Unrealized
SANA SANA BIOTECHNOLOGY INC 0.6%
Value $65.44M Shares 18,750,000 Est. Cost Unrealized
PRLD PRELUDE THERAPEUTICS INC 0.3%
Value $34.52M Shares 6,475,882 Est. Cost Unrealized
QTTB Q32 BIO INC 0.3%
Value $29.72M Shares 2,332,457 Est. Cost Unrealized
EDIT EDITAS MEDICINE INC 0.3%
Value $28.8M Shares 8,889,000 Est. Cost Unrealized
ALT ALTIMMUNE INC 0.2%
Value $19.76M Shares 6,500,000 Est. Cost Unrealized
SNSE FAETH THERAPEUTICS INC 0.2%
Value $18.05M Shares 722,020 Est. Cost Unrealized
AURA AURA BIOSCIENCES INC 0.2%
Value $17.75M Shares 2,500,000 Est. Cost Unrealized
SPTX SEAPORT THERAPEUTICS INC 0.1%
Value $15.2M Shares 700,000 Est. Cost Unrealized
JATT JATT II ACQUISITION CORP 0.0%
Value $5.68M Shares 500,000 Est. Cost Unrealized
AMAN AMANAT ACQUISITION CORP CL A 0.0%
Value $3.81M Shares 375,000 Est. Cost Unrealized

Increased Positions (8)

Exited Positions (18)

ASND ASCENDIS PHARMA A/S - ADR 20.4%
Value $2.352B Shares 10,281,496 Est. Cost Unrealized
DNTH DIANTHUS THERAPEUTICS INC 1.9%
Value $219M Shares 2,611,733 Est. Cost Unrealized
PRAX PRAXIS PRECISION MEDICINES I 1.0%
Value $120M Shares 373,787 Est. Cost Unrealized
SRPT SAREPTA THERAPEUTICS INC 0.7%
Value $84.92M Shares 3,902,596 Est. Cost Unrealized
SYRE SPYRE THERAPEUTICS INC 0.7%
Value $81.79M Shares 1,621,620 Est. Cost Unrealized
FULC FULCRUM THERAPEUTICS INC 0.4%
Value $46.43M Shares 6,053,960 Est. Cost Unrealized
OLMA OLEMA PHARMACEUTICALS INC 0.3%
Value $38.77M Shares 2,600,000 Est. Cost Unrealized
DSGN DESIGN THERAPEUTICS INC 0.3%
Value $31.63M Shares 2,972,973 Est. Cost Unrealized
TVTX TRAVERE THERAPEUTICS INC 0.2%
Value $22.19M Shares 746,841 Est. Cost Unrealized
GRAL GRAIL INC 0.2%
Value $22.13M Shares 428,266 Est. Cost Unrealized
RLMD RELMADA THERAPEUTICS INC 0.2%
Value $20.51M Shares 2,947,369 Est. Cost Unrealized
STRO SUTRO BIOPHARMA INC 0.2%
Value $17.82M Shares 715,307 Est. Cost Unrealized
CTNM CONTINEUM THERAPEUTICS INC-A 0.1%
Value $16.93M Shares 1,296,012 Est. Cost Unrealized
INSP INSPIRE MEDICAL SYSTEMS INC 0.1%
Value $16.8M Shares 325,663 Est. Cost Unrealized
HNGE HINGE HEALTH INC-A 0.1%
Value $14.06M Shares 364,613 Est. Cost Unrealized
WGS GENEDX HOLDINGS CORP 0.1%
Value $13.48M Shares 209,887 Est. Cost Unrealized
RNA ATRIUM THERAPEUTICS INC 0.1%
Value $11.55M Shares 864,102 Est. Cost Unrealized
MPLT MAPLIGHT THERAPEUTICS INC 0.0%
Value $5.048M Shares 248,294 Est. Cost Unrealized

Decreased Positions (9)

Unchanged Positions (50)

RYTM RHYTHM PHARMACEUTICALS INC 6.4%
Value $740M Shares 6,666,837 Est. Cost Unrealized
GHRS GH RESEARCH PLC 1.8%
Value $205M Shares 7,636,813 Est. Cost Unrealized
TYRA TYRA BIOSCIENCES INC 3.4%
Value $390M Shares 12,198,625 Est. Cost Unrealized
BCAX BICARA THERAPEUTICS INC 1.9%
Value $215M Shares 7,255,993 Est. Cost Unrealized
CLYM CLIMB BIO INC 1.3%
Value $147M Shares 11,300,939 Est. Cost Unrealized
SEPN SEPTERNA INC 2.0%
Value $234M Shares 6,995,858 Est. Cost Unrealized
TSHA TAYSHA GENE THERAPIES INC 1.4%
Value $160M Shares 23,555,648 Est. Cost Unrealized
WVE WAVE LIFE SCIENCES LTD 1.4%
Value $157M Shares 26,975,505 Est. Cost Unrealized
SION SIONNA THERAPEUTICS INC 3.8%
Value $436M Shares 9,905,045 Est. Cost Unrealized
EVMN EVOMMUNE INC 0.4%
Value $46.44M Shares 3,494,638 Est. Cost Unrealized
JBIO JADE BIOSCIENCES INC 0.7%
Value $81.57M Shares 3,671,083 Est. Cost Unrealized
SGP SPYGLASS PHARMA INC 1.6%
Value $179M Shares 8,021,117 Est. Cost Unrealized
MNPR MONOPAR THERAPEUTICS INC 0.5%
Value $61.78M Shares 667,207 Est. Cost Unrealized
IRON DISC MEDICINE INC 1.6%
Value $179M Shares 2,450,221 Est. Cost Unrealized
FDMT 4D MOLECULAR THERAPEUTICS IN 0.6%
Value $67.16M Shares 5,049,779 Est. Cost Unrealized
NAMS NEWAMSTERDAM PHARMA CO NV 2.8%
Value $324M Shares 9,550,191 Est. Cost Unrealized
LBRX LB PHARMACEUTICALS INC 0.6%
Value $71.68M Shares 2,208,604 Est. Cost Unrealized
JANX JANUX THERAPEUTICS INC 1.5%
Value $172M Shares 11,189,693 Est. Cost Unrealized
CCCC C4 THERAPEUTICS INC 0.3%
Value $37.36M Shares 8,000,000 Est. Cost Unrealized
LENZ LENZ THERAPEUTICS INC 0.2%
Value $23.74M Shares 4,178,823 Est. Cost Unrealized
AVR ANTERIS TECHNOLOGIES GLOBAL 0.3%
Value $29.55M Shares 3,000,000 Est. Cost Unrealized
CAPR CAPRICOR THERAPEUTICS INC 0.3%
Value $36.31M Shares 1,507,844 Est. Cost Unrealized
KPTI KARYOPHARM THERAPEUTICS INC 0.2%
Value $18.73M Shares 1,917,354 Est. Cost Unrealized
MIRM MIRUM PHARMACEUTICALS INC 0.3%
Value $37.29M Shares 318,554 Est. Cost Unrealized
NKTX NKARTA INC 0.3%
Value $30.58M Shares 10,805,129 Est. Cost Unrealized
BCRX BIOCRYST PHARMACEUTICALS INC 1.4%
Value $158M Shares 15,827,186 Est. Cost Unrealized
ABOS ACUMEN PHARMACEUTICALS INC 0.5%
Value $56.05M Shares 20,992,669 Est. Cost Unrealized
LXEO LEXEO THERAPEUTICS INC 0.2%
Value $23.27M Shares 5,000,000 Est. Cost Unrealized
BNTC BENITEC BIOPHARMA INC 0.2%
Value $24.75M Shares 1,850,000 Est. Cost Unrealized
EQ EQUILLIUM INC 0.1%
Value $9.908M Shares 3,096,336 Est. Cost Unrealized
IPSC CENTURY THERAPEUTICS INC 0.4%
Value $43.5M Shares 17,754,430 Est. Cost Unrealized
MGNX MACROGENICS INC 0.1%
Value $8.612M Shares 1,864,176 Est. Cost Unrealized
PALI PALISADE BIO INC 0.1%
Value $14.89M Shares 7,124,116 Est. Cost Unrealized
WAY WAYSTAR HOLDING CORP 0.1%
Value $10.87M Shares 529,400 Est. Cost Unrealized
ZLAB ZAI LAB LTD-ADR 0.9%
Value $109M Shares 5,743,533 Est. Cost Unrealized
OKUR ONKURE THERAPEUTICS INC-A 0.2%
Value $18.23M Shares 3,998,333 Est. Cost Unrealized
MLYS MINERALYS THERAPEUTICS INC 1.8%
Value $208M Shares 7,692,750 Est. Cost Unrealized
ALXO ALX ONCOLOGY HOLDINGS INC 0.2%
Value $26.93M Shares 13,011,849 Est. Cost Unrealized
DRUG BRIGHT MINDS BIOSCIENCES INC 0.2%
Value $18.6M Shares 265,000 Est. Cost Unrealized
PEPG PEPGEN INC 0.3%
Value $36.12M Shares 20,064,545 Est. Cost Unrealized
HLXC HELIX ACQUISITION CORP-CL A 0.1%
Value $13.3M Shares 1,250,000 Est. Cost Unrealized
NAMSW NEWAMSTERDAM PHARMA CO NV-27 0.1%
Value $7.123M Shares 333,333 Est. Cost Unrealized
SABS SAB BIOTHERAPEUTICS INC 0.1%
Value $17.17M Shares 4,401,500 Est. Cost Unrealized
ASMB ASSEMBLY BIOSCIENCES INC 0.2%
Value $28.04M Shares 1,020,410 Est. Cost Unrealized
GLTO DAMORA THERAPEUTICS INC 0.5%
Value $62.42M Shares 2,399,702 Est. Cost Unrealized
PCVX VAXCYTE INC 5.8%
Value $667M Shares 11,474,599 Est. Cost Unrealized
RANI RANI THERAPEUTICS HOLDINGS-A 0.1%
Value $6.463M Shares 8,500,000 Est. Cost Unrealized
SPRY ARS PHARMACEUTICALS INC 0.8%
Value $87M Shares 10,860,977 Est. Cost Unrealized
CRVS CORVUS PHARMACEUTICALS INC 0.1%
Value $6.723M Shares 450,000 Est. Cost Unrealized
PCSC PERCEPTIVE CAPITAL SOLUTIONS 0.1%
Value $8.16M Shares 750,000 Est. Cost Unrealized