Location: Zurich, Switzerland
CIK: 0001674546 · Show all filings
Period: Q3 2023 (← Previous) (Next →)
Filing Date: Nov 14, 2023
Total Value: $6.207B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| ARGX | ARGENX SE | 911,530 | $448M | 7.2% | $157.09 | — | SPONSORED ADR | 04016X101 |
| IONS | IONIS PHARMACEUTICALS INC | 9,233,700 | $419M | 6.7% | $61.40 | -32.8% | COM | 462222100 |
| VRTX | VERTEX PHARMACEUTICALS INC | 1,002,735 | $349M | 5.6% | $197.89 | +76.7% | COM | 92532F100 |
| NBIX | NEUROCRINE BIOSCIENCES INC | 2,583,550 | $291M | 4.7% | $83.66 | +25.9% | COM | 64125C109 |
| ISRG | INTUITIVE SURGICAL INC | 828,999 | $242M | 3.9% | $268.75 | +16.2% | COM NEW | 46120E602 |
| — | INTRA-CELLULAR THERAPIES INC | 3,170,250 | $165M | 2.7% | $14.96 | — | COM | 46116X101 |
| ALNY | ALNYLAM PHARMACEUTICALS INC | 894,345 | $158M | 2.6% | $83.60 | +128.6% | COM | 02043Q107 |
| MRNA | MODERNA INC | 1,495,325 | $154M | 2.5% | $23.27 | +379.3% | COM | 60770K107 |
| ABT | ABBOTT LABS | 1,560,968 | $151M | 2.4% | $72.85 | +37.9% | COM | 002824100 |
| INCY | INCYTE CORP | 2,491,450 | $144M | 2.3% | $80.18 | -21.4% | COM | 45337C102 |
| BSX | BOSTON SCIENTIFIC CORP | 2,646,295 | $140M | 2.3% | $36.97 | +41.9% | COM | 101137107 |
| RVMD | REVOLUTION MEDICINES INC | 4,721,500 | $131M | 2.1% | $30.94 | -4.1% | COM | 76155X100 |
| UNH | UNITEDHEALTH GROUP INC | 258,205 | $130M | 2.1% | $278.27 | +68.9% | COM | 91324P102 |
| SYK | STRYKER CORPORATION | 475,613 | $130M | 2.1% | $184.08 | +52.1% | COM | 863667101 |
| — | AXONICS INC | 2,252,851 | $126M | 2.0% | $51.23 | — | COM | 05465P101 |
| EVH | EVOLENT HEALTH INC | 3,677,115 | $100M | 1.6% | $21.60 | +28.7% | CL A | 30050B101 |
| AGIO | AGIOS PHARMACEUTICALS INC | 4,013,500 | $99.33M | 1.6% | $50.16 | -47.3% | COM | 00847X104 |
| HUM | HUMANA INC | 170,046 | $82.73M | 1.3% | $404.81 | +12.8% | COM | 444859102 |
| INSM | INSMED INC | 3,162,735 | $79.86M | 1.3% | $28.84 | -20.7% | COM PAR $.01 | 457669307 |
| BDX | BECTON DICKINSON & CO | 304,230 | $78.65M | 1.3% | $212.26 | +21.7% | COM | 075887109 |
| EXAS | EXACT SCIENCES CORP | 1,119,819 | $76.39M | 1.2% | $71.86 | +18.1% | COM | 30063P105 |
| ELV | ELEVANCE HEALTH INC | 173,887 | $75.71M | 1.2% | $336.09 | +29.9% | COM | 036752103 |
| OPCH | OPTION CARE HEALTH INC | 2,284,293 | $73.9M | 1.2% | $21.26 | +58.5% | COM NEW | 68404L201 |
| — | SAGE THERAPEUTICS INC | 3,513,351 | $72.3M | 1.2% | $93.30 | — | COM | 78667J108 |
| EW | EDWARDS LIFESCIENCES CORP | 1,025,457 | $71.04M | 1.1% | $72.79 | +10.4% | COM | 28176E108 |
| DXCM | DEXCOM INC | 685,733 | $63.98M | 1.0% | $89.53 | +25.9% | COM | 252131107 |
| PACB | PACIFIC BIOSCIENCES CALIF IN | 7,245,188 | $60.5M | 1.0% | $9.15 | +24.9% | COM | 69404D108 |
| PEN | PENUMBRA INC | 237,252 | $57.39M | 0.9% | $200.63 | +38.4% | COM | 70975L107 |
| CLDX | CELLDEX THERAPEUTICS INC NEW | 1,900,000 | $52.29M | 0.8% | $29.91 | +4.8% | COM NEW | 15117B202 |
| MOH | MOLINA HEALTHCARE INC | 158,438 | $51.95M | 0.8% | $221.68 | +42.0% | COM | 60855R100 |
| EXEL | EXELIXIS INC | 2,375,925 | $51.91M | 0.8% | $20.80 | +0.5% | COM | 30161Q104 |
| ALGN | ALIGN TECHNOLOGY INC | 166,886 | $50.95M | 0.8% | $316.81 | +9.1% | COM | 016255101 |
| — | SHOCKWAVE MED INC | 254,279 | $50.63M | 0.8% | $80.46 | — | COM | 82489T104 |
| MDT | MEDTRONIC PLC | 641,492 | $50.27M | 0.8% | $81.67 | -4.7% | SHS | G5960L103 |
| IDXX | IDEXX LABS INC | 114,441 | $50.04M | 0.8% | $365.32 | +36.5% | COM | 45168D104 |
| BIO | BIO RAD LABS INC | 134,330 | $48.15M | 0.8% | $491.45 | -21.5% | CL A | 090572207 |
| — | ACCOLADE INC | 4,527,923 | $47.91M | 0.8% | $28.83 | — | COM | 00437E102 |
| MGNX | MACROGENICS INC | 9,803,313 | $45.68M | 0.7% | $16.42 | -69.7% | COM | 556099109 |
| VEEV | VEEVA SYS INC | 224,100 | $45.59M | 0.7% | $197.26 | +2.1% | CL A COM | 922475108 |
| CRL | CHARLES RIV LABS INTL INC | 229,342 | $44.95M | 0.7% | $236.25 | -13.1% | COM | 159864107 |
| TNDM | TANDEM DIABETES CARE INC | 2,142,769 | $44.51M | 0.7% | $69.46 | -60.5% | COM NEW | 875372203 |
| AXSM | AXSOME THERAPEUTICS INC | 631,487 | $44.13M | 0.7% | $54.10 | +38.2% | COM | 05464T104 |
| LLY | ELI LILLY & CO | 81,541 | $43.8M | 0.7% | $400.21 | +26.6% | COM | 532457108 |
| PODD | INSULET CORP | 264,359 | $42.16M | 0.7% | $212.68 | +5.3% | COM | 45784P101 |
| ARVN | ARVINAS INC | 2,125,200 | $41.74M | 0.7% | $34.23 | -28.3% | COM | 04335A105 |
| RLAY | RELAY THERAPEUTICS INC | 4,885,000 | $41.08M | 0.7% | $31.74 | -66.1% | COM | 75943R102 |
| CRSP | CRISPR THERAPEUTICS AG | 898,400 | $40.78M | 0.7% | $55.85 | -7.5% | NAMEN AKT | H17182108 |
| HCA | HCA HEALTHCARE INC | 155,643 | $38.29M | 0.6% | $134.82 | +99.1% | COM | 40412C101 |
| CI | THE CIGNA GROUP | 125,502 | $35.9M | 0.6% | $233.53 | +16.8% | COM | 125523100 |
| JAZZ | JAZZ PHARMACEUTICALS PLC | 266,226 | $34.46M | 0.6% | $147.29 | -9.5% | SHS USD | G50871105 |
| DHR | DANAHER CORPORATION | 136,533 | $33.87M | 0.5% | $150.04 | +46.7% | COM | 235851102 |
| TMO | THERMO FISHER SCIENTIFIC INC | 66,468 | $33.64M | 0.5% | $467.41 | +13.2% | COM | 883556102 |
| ATRC | ATRICURE INC | 747,560 | $32.74M | 0.5% | $51.95 | -6.1% | COM | 04963C209 |
| ZBH | ZIMMER BIOMET HOLDINGS INC | 284,888 | $31.97M | 0.5% | $119.20 | +4.2% | COM | 98956P102 |
| BMRN | BIOMARIN PHARMACEUTICAL INC | 349,888 | $30.96M | 0.5% | $92.60 | -3.9% | COM | 09061G101 |
| CNC | CENTENE CORP DEL | 444,043 | $30.59M | 0.5% | $64.99 | +2.4% | COM | 15135B101 |
| HCM | HUTCHMED CHINA LTD | 1,802,963 | $30.58M | 0.5% | $24.55 | — | SPONSORED ADS | 44842L103 |
| IQV | IQVIA HLDGS INC | 155,220 | $30.54M | 0.5% | $227.21 | -4.4% | COM | 46266C105 |
| GMED | GLOBUS MED INC | 609,615 | $30.27M | 0.5% | $54.84 | +2.0% | CL A | 379577208 |
| APLS | APELLIS PHARMACEUTICALS INC | 793,841 | $30.2M | 0.5% | $43.19 | +1.7% | COM | 03753U106 |
| MRK | MERCK & CO INC | 291,896 | $30.05M | 0.5% | $104.01 | -4.0% | COM | 58933Y105 |
| TMDX | TRANSMEDICS GROUP INC | 536,737 | $29.39M | 0.5% | $22.15 | +224.9% | COM | 89377M109 |
| SRPT | SAREPTA THERAPEUTICS INC | 241,752 | $29.31M | 0.5% | $84.67 | +33.5% | COM | 803607100 |
| PRCT | PROCEPT BIOROBOTICS CORP | 888,296 | $29.14M | 0.5% | $35.93 | -5.1% | COM | 74276L105 |
| CDNA | CAREDX INC | 3,940,798 | $27.59M | 0.4% | $33.63 | -72.5% | COM | 14167L103 |
| — | COOPER COS INC | 86,567 | $27.53M | 0.4% | $341.81 | — | COM NEW | 216648402 |
| — | OUTSET MED INC | 2,408,430 | $26.2M | 0.4% | $37.68 | — | COM | 690145107 |
| WVE | WAVE LIFE SCIENCES LTD | 4,494,458 | $25.84M | 0.4% | $16.12 | -71.7% | SHS | Y95308105 |
| — | ESSA PHARMA INC | 7,898,583 | $24.41M | 0.4% | $12.40 | — | COM NEW | 29668H708 |
| PRVA | PRIVIA HEALTH GROUP INC | 1,055,178 | $24.27M | 0.4% | $31.57 | -19.4% | COM | 74276R102 |
| BDTX | BLACK DIAMOND THERAPEUTICS I | 8,135,839 | $23.35M | 0.4% | $11.71 | -68.6% | COM | 09203E105 |
| — | SILK RD MED INC | 1,430,562 | $21.44M | 0.3% | $43.14 | — | COM | 82710M100 |
| CSTL | CASTLE BIOSCIENCES INC | 1,228,031 | $20.74M | 0.3% | $31.35 | -44.2% | COM | 14843C105 |
| HOLX | HOLOGIC INC | 290,136 | $20.14M | 0.3% | $59.24 | +27.6% | COM | 436440101 |
| LEGN | LEGEND BIOTECH CORP | 278,154 | $18.68M | 0.3% | $41.55 | — | SPONSORED ADS | 52490G102 |
| BEAM | BEAM THERAPEUTICS INC | 694,821 | $16.71M | 0.3% | $60.73 | -55.9% | COM | 07373V105 |
| SUPN | SUPERNUS PHARMACEUTICALS INC | 580,600 | $16.01M | 0.3% | $34.35 | -11.4% | COM | 868459108 |
| — | POINT BIOPHARMA GLOBAL INC | 2,351,160 | $15.68M | 0.3% | $7.95 | — | COM | 730541109 |
| SRRK | SCHOLAR ROCK HLDG CORP | 2,137,925 | $15.18M | 0.2% | $17.34 | -61.2% | COM | 80706P103 |
| INSP | INSPIRE MED SYS INC | 70,368 | $13.96M | 0.2% | $115.41 | +118.5% | COM | 457730109 |
| — | VERONA PHARMA PLC | 856,358 | $13.96M | 0.2% | $19.21 | — | SPONSORED ADS | 925050106 |
| — | GENERATION BIO CO | 3,617,080 | $13.71M | 0.2% | $18.19 | — | COM | 37148K100 |
| AMGN | AMGEN INC | 48,473 | $13.03M | 0.2% | $204.07 | +13.6% | COM | 031162100 |
| REGN | REGENERON PHARMACEUTICALS | 14,939 | $12.29M | 0.2% | $497.97 | +57.0% | COM | 75886F107 |
| TXG | 10X GENOMICS INC | 294,432 | $12.15M | 0.2% | $86.25 | -39.7% | CL A COM | 88025U109 |
| NTRA | NATERA INC | 257,686 | $11.4M | 0.2% | $43.70 | +16.7% | COM | 632307104 |
| RMD | RESMED INC | 76,696 | $11.34M | 0.2% | $131.86 | +34.0% | COM | 761152107 |
| PHR | PHREESIA INC | 579,039 | $10.82M | 0.2% | $34.59 | -22.2% | COM | 71944F106 |
| OMCL | OMNICELL COM | 239,279 | $10.78M | 0.2% | $83.27 | -27.2% | COM | 68213N109 |
| FATE | FATE THERAPEUTICS INC | 4,851,579 | $10.29M | 0.2% | $40.00 | -91.7% | COM | 31189P102 |
| — | AMEDISYS INC | 106,387 | $9.937M | 0.2% | $153.20 | — | COM | 023436108 |
| ILMN | ILLUMINA INC | 72,030 | $9.888M | 0.2% | $282.52 | -41.8% | COM | 452327109 |
| ONC | BEIGENE LTD | 53,200 | $9.504M | 0.2% | $184.58 | — | SPONSORED ADR | 07725L102 |
| DOCS | DOXIMITY INC | 399,457 | $8.476M | 0.1% | $36.02 | -24.2% | CL A | 26622P107 |
| GILD | GILEAD SCIENCES INC | 107,350 | $8.045M | 0.1% | $60.98 | +15.9% | COM | 375558103 |
| — | MERSANA THERAPEUTICS INC | 5,218,625 | $6.628M | 0.1% | $15.10 | — | COM | 59045L106 |
| TDOC | TELADOC HEALTH INC | 355,649 | $6.612M | 0.1% | $109.52 | -78.7% | COM | 87918A105 |
| — | MOLECULAR TEMPLATES INC | 1,031,613 | $6.52M | 0.1% | $6.32 | — | COM NEW | 608550208 |
| AZN | ASTRAZENECA PLC | 84,600 | $5.726M | 0.1% | $64.97 | — | SPONSORED ADR | 046353108 |
| RDY | DR REDDYS LABS LTD | 80,200 | $5.414M | 0.1% | $51.49 | — | ADR | 256135203 |
| — | SEAGEN INC | 22,000 | $4.667M | 0.1% | $170.06 | — | COM | 81181C104 |
| BIIB | BIOGEN INC | 17,314 | $4.45M | 0.1% | $249.86 | +7.0% | COM | 09062X103 |
| ESPR | ESPERION THERAPEUTICS INC NE | 4,204,264 | $4.12M | 0.1% | $43.86 | -96.7% | COM | 29664W105 |
| — | NEVRO CORP | 198,171 | $3.809M | 0.1% | $97.81 | — | COM | 64157F103 |
| JNJ | JOHNSON & JOHNSON | 22,823 | $3.555M | 0.1% | $139.98 | +9.5% | COM | 478160104 |
| — | OLINK HLDG AB | 217,256 | $3.205M | 0.1% | $32.23 | — | SPONSORED ADS | 680710100 |
| COR | CENCORA INC | 17,087 | $3.075M | 0.0% | $145.42 | +24.5% | COM | 03073E105 |
| CVS | CVS HEALTH CORP | 35,314 | $2.466M | 0.0% | $65.07 | -0.8% | COM | 126650100 |
| MCK | MCKESSON CORP | 5,425 | $2.359M | 0.0% | $298.67 | +39.5% | COM | 58155Q103 |
| KOS | KOSMOS ENERGY LTD | 284,000 | $2.323M | 0.0% | $3.22 | +119.9% | COM | 500688106 |
| ALKS | ALKERMES PLC | 81,700 | $2.288M | 0.0% | $26.45 | +10.8% | SHS | G01767105 |
| GH | GUARDANT HEALTH INC | 74,525 | $2.209M | 0.0% | $73.85 | -52.4% | COM | 40131M109 |
| BBIO | BRIDGEBIO PHARMA INC | 78,700 | $2.075M | 0.0% | $12.16 | +133.4% | COM | 10806X102 |
| VTRS | VIATRIS INC | 176,848 | $1.744M | 0.0% | $9.34 | 0.0% | COM | 92556V106 |
| RYTM | RHYTHM PHARMACEUTICALS INC | 73,300 | $1.68M | 0.0% | $22.39 | 0.0% | COM | 76243J105 |
| PCVX | VAXCYTE INC | 30,500 | $1.555M | 0.0% | $47.69 | +3.5% | COM | 92243G108 |
| KRYS | KRYSTAL BIOTECH INC | 12,500 | $1.45M | 0.0% | $61.97 | +96.9% | COM | 501147102 |
| — | LABORATORY CORP AMER HLDGS | 6,988 | $1.405M | 0.0% | $233.68 | — | COM NEW | 50540R409 |
| CERT | CERTARA INC | 91,606 | $1.332M | 0.0% | $16.81 | 0.0% | COM | 15687V109 |
| RXRX | RECURSION PHARMACEUTICALS IN | 174,085 | $1.332M | 0.0% | $9.98 | 0.0% | CL A | 75629V104 |
| — | AKERO THERAPEUTICS INC | 25,000 | $1.264M | 0.0% | $35.00 | — | COM | 00973Y108 |
| — | DYNAVAX TECHNOLOGIES CORP | 83,200 | $1.229M | 0.0% | $14.77 | — | COM NEW | 268158201 |
| — | KARUNA THERAPEUTICS INC | 6,900 | $1.167M | 0.0% | $202.14 | — | COM | 48576A100 |
| ZTS | ZOETIS INC | 6,462 | $1.124M | 0.0% | $166.19 | +6.5% | CL A | 98978V103 |
| SPY | SPDR S&P 500 ETF TR | 2,600 | $1.111M | 0.0% | $378.84 | — | TR UNIT | 78462F103 |
| CYTK | CYTOKINETICS INC | 37,100 | $1.093M | 0.0% | $36.38 | -8.5% | COM NEW | 23282W605 |
| — | MERUS N V | 44,500 | $1.049M | 0.0% | $18.01 | — | COM | N5749R100 |
| IMCR | IMMUNOCORE HLDGS PLC | 19,850 | $1.03M | 0.0% | $51.90 | — | ADS | 45258D105 |
| VRDN | VIRIDIAN THERAPEUTICS INC | 63,770 | $978K | 0.0% | $15.15 | +25.9% | COM | 92790C104 |
| — | INHIBRX INC | 48,800 | $895K | 0.0% | $29.83 | — | COM | 45720L107 |
| GDX | VANECK ETF TRUST | 33,000 | $888K | 0.0% | $34.23 | — | GOLD MINERS ETF | 92189F106 |
| VTYX | VENTYX BIOSCIENCES INC | 24,500 | $851K | 0.0% | $38.88 | -11.1% | COM | 92332V107 |
| GEHC | GE HEALTHCARE TECHNOLOGIES I | 12,500 | $851K | 0.0% | $72.48 | 0.0% | COMMON STOCK | 36266G107 |
| GPCR | STRUCTURE THERAPEUTICS INC | 16,800 | $847K | 0.0% | $50.42 | — | SPONSORD ADS | 86366E106 |
| XENE | XENON PHARMACEUTICALS INC | 23,900 | $816K | 0.0% | $39.75 | -5.9% | COM | 98420N105 |
| GOOG | ALPHABET INC | 6,000 | $791K | 0.0% | $111.55 | +15.7% | CAP STK CL C | 02079K107 |
| BCYC | BICYCLE THERAPEUTICS PLC | 39,200 | $788K | 0.0% | $24.44 | — | SPONSORED ADS | 088786108 |
| ABBV | ABBVIE INC | 4,763 | $710K | 0.0% | $125.65 | +7.7% | COM | 00287Y109 |
| — | 89BIO INC | 39,200 | $605K | 0.0% | $15.23 | — | COM | 282559103 |
| XOP | SPDR SER TR | 3,900 | $577K | 0.0% | $124.62 | — | S&P OILGAS EXP | 78468R556 |
| PTGX | PROTAGONIST THERAPEUTICS INC | 30,000 | $500K | 0.0% | $19.40 | 0.0% | COM | 74366E102 |
| PFE | PFIZER INC | 9,555 | $317K | 0.0% | $30.57 | 0.0% | COM | 717081103 |
| SEER | SEER INC | 123,426 | $273K | 0.0% | $57.71 | -94.0% | COM CL A | 81578P106 |
| MCHI | ISHARES TR | 4,100 | $177K | 0.0% | $55.85 | — | MSCI CHINA ETF | 46429B671 |
| DGX | QUEST DIAGNOSTICS INC | 1,324 | $161K | 0.0% | $132.87 | -4.2% | COM | 74834L100 |
| GDXJ | VANECK ETF TRUST | 5,000 | $161K | 0.0% | $32.00 | — | JUNIOR GOLD MINE | 92189F791 |
| — | GRACELL BIOTECHNOLOGIES INC | 38,000 | $109K | 0.0% | $3.81 | — | SPONSORED ADS | 38406L103 |
| THC | TENET HEALTHCARE CORP | 700 | $46,123 | 0.0% | $71.35 | +4.8% | COM NEW | 88033G407 |
| EQIX | EQUINIX INC | 40 | $29,050 | 0.0% | $738.08 | -0.3% | COM | 29444U700 |
| EVTC | EVERTEC INC | 739 | $27,476 | 0.0% | $45.34 | -15.0% | COM | 30040P103 |
| INFY | INFOSYS LTD | 1,130 | $19,600 | 0.0% | $25.66 | — | SPONSORED ADR | 456788108 |
| UMC | UNITED MICROELECTRONICS CORP | 2,698 | $18,911 | 0.0% | $5.56 | — | SPON ADR NEW | 910873405 |
| TSM | TAIWAN SEMICONDUCTOR MFG LTD | 1,089 | $1,963 | 0.0% | $78.23 | — | SPONSORED ADS | 874039100 |
| ASR | GRUPO AEROPORTUARIO DEL SURE | 135 | $165 | 0.0% | $207.41 | — | SPON ADR SER B | 40051E202 |