Location: Zurich, Switzerland
CIK: 0001674546 · Show all filings
Period: Q4 2024 (← Previous) (Next →)
Filing Date: Feb 14, 2025
Total Value: $5.195B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| ARGX | ARGENX SE | 593,184 | $365M | 7.0% | $157.09 | — | SPONSORED ADR | 04016X101 |
| IONS | IONIS PHARMACEUTICALS INC | 7,868,700 | $275M | 5.3% | $61.40 | -39.1% | COM | 462222100 |
| NBIX | NEUROCRINE BIOSCIENCES INC | 1,820,000 | $248M | 4.8% | $83.66 | +47.8% | COM | 64125C109 |
| ISRG | INTUITIVE SURGICAL INC | 464,377 | $242M | 4.7% | $268.75 | +93.8% | COM NEW | 46120E602 |
| — | INTRA-CELLULAR THERAPIES INC | 2,440,240 | $204M | 3.9% | $14.96 | — | COM | 46116X101 |
| VRTX | VERTEX PHARMACEUTICALS INC | 487,434 | $196M | 3.8% | $197.89 | +134.2% | COM | 92532F100 |
| RVMD | REVOLUTION MEDICINES INC | 4,386,900 | $192M | 3.7% | $30.44 | +65.8% | COM | 76155X100 |
| ABT | ABBOTT LABS | 1,688,660 | $191M | 3.7% | $78.52 | +44.3% | COM | 002824100 |
| BSX | BOSTON SCIENTIFIC CORP | 2,135,295 | $191M | 3.7% | $39.68 | +121.8% | COM | 101137107 |
| SYK | STRYKER CORPORATION | 520,026 | $187M | 3.6% | $210.49 | +74.0% | COM | 863667101 |
| ALNY | ALNYLAM PHARMACEUTICALS INC | 770,268 | $181M | 3.5% | $86.59 | +203.7% | COM | 02043Q107 |
| INCY | INCYTE CORP | 2,157,478 | $149M | 2.9% | $80.18 | -11.1% | COM | 45337C102 |
| AGIO | AGIOS PHARMACEUTICALS INC | 3,515,150 | $116M | 2.2% | $50.16 | -6.3% | COM | 00847X104 |
| SRRK | SCHOLAR ROCK HLDG CORP | 2,510,690 | $109M | 2.1% | $19.40 | +67.9% | COM | 80706P103 |
| PODD | INSULET CORP | 321,917 | $84.04M | 1.6% | $199.47 | +26.3% | COM | 45784P101 |
| MDT | MEDTRONIC PLC | 1,042,948 | $83.31M | 1.6% | $78.48 | +6.8% | SHS | G5960L103 |
| EW | EDWARDS LIFESCIENCES CORP | 1,097,848 | $81.27M | 1.6% | $75.51 | -7.3% | COM | 28176E108 |
| DXCM | DEXCOM INC | 1,045,044 | $81.27M | 1.6% | $101.18 | -26.8% | COM | 252131107 |
| UNH | UNITEDHEALTH GROUP INC | 159,713 | $80.79M | 1.6% | $361.14 | +53.1% | COM | 91324P102 |
| CLDX | CELLDEX THERAPEUTICS INC NEW | 3,071,615 | $77.62M | 1.5% | $31.92 | -14.9% | COM NEW | 15117B202 |
| BDX | BECTON DICKINSON & CO | 337,548 | $76.58M | 1.5% | $218.37 | +3.1% | COM | 075887109 |
| BHVN | BIOHAVEN LTD | 2,040,853 | $76.23M | 1.5% | $35.46 | +31.6% | COM | G1110E107 |
| MRNA | MODERNA INC | 1,600,877 | $66.56M | 1.3% | $37.72 | +26.7% | COM | 60770K107 |
| PEN | PENUMBRA INC | 238,053 | $56.53M | 1.1% | $200.28 | +13.5% | COM | 70975L107 |
| WVE | WAVE LIFE SCIENCES LTD | 4,094,458 | $50.65M | 1.0% | $16.12 | -17.2% | SHS | Y95308105 |
| ARVN | ARVINAS INC | 2,389,600 | $45.81M | 0.9% | $32.58 | -25.4% | COM | 04335A105 |
| GEHC | GE HEALTHCARE TECHNOLOGIES I | 524,414 | $41M | 0.8% | $70.33 | +20.6% | COMMON STOCK | 36266G107 |
| EXAS | EXACT SCIENCES CORP | 694,056 | $39M | 0.8% | $67.99 | -8.5% | COM | 30063P105 |
| EWTX | EDGEWISE THERAPEUTICS INC | 1,428,929 | $38.15M | 0.7% | $17.44 | +82.6% | COM | 28036F105 |
| BEAM | BEAM THERAPEUTICS INC | 1,518,121 | $37.65M | 0.7% | $43.36 | -41.1% | COM | 07373V105 |
| PRCT | PROCEPT BIOROBOTICS CORP | 462,894 | $37.27M | 0.7% | $35.93 | +137.8% | COM | 74276L105 |
| RMD | RESMED INC | 160,793 | $36.77M | 0.7% | $187.63 | +27.1% | COM | 761152107 |
| IMCR | IMMUNOCORE HLDGS PLC | 1,205,464 | $35.56M | 0.7% | $61.27 | — | ADS | 45258D105 |
| LLY | ELI LILLY & CO | 45,465 | $35.1M | 0.7% | $420.39 | +95.3% | COM | 532457108 |
| CI | THE CIGNA GROUP | 125,205 | $34.57M | 0.7% | $271.36 | +14.8% | COM | 125523100 |
| ALGN | ALIGN TECHNOLOGY INC | 160,003 | $33.36M | 0.6% | $307.47 | -27.3% | COM | 016255101 |
| COO | COOPER COS INC | 357,130 | $32.83M | 0.6% | $96.75 | +5.3% | COM | 216648501 |
| MGNX | MACROGENICS INC | 9,929,963 | $32.27M | 0.6% | $16.28 | -77.9% | COM | 556099109 |
| IDXX | IDEXX LABS INC | 76,935 | $31.81M | 0.6% | $365.32 | +20.1% | COM | 45168D104 |
| TMO | THERMO FISHER SCIENTIFIC INC | 60,962 | $31.71M | 0.6% | $510.33 | +7.3% | COM | 883556102 |
| ZBH | ZIMMER BIOMET HOLDINGS INC | 293,621 | $31.02M | 0.6% | $118.00 | -10.2% | COM | 98956P102 |
| RLAY | RELAY THERAPEUTICS INC | 7,377,292 | $30.39M | 0.6% | $23.61 | -77.0% | COM | 75943R102 |
| GMED | GLOBUS MED INC | 362,979 | $30.02M | 0.6% | $54.84 | +43.8% | CL A | 379577208 |
| CDNA | CAREDX INC | 1,374,412 | $29.43M | 0.6% | $33.63 | -27.7% | COM | 14167L103 |
| TNDM | TANDEM DIABETES CARE INC | 782,456 | $28.18M | 0.5% | $64.27 | -47.4% | COM NEW | 875372203 |
| DHR | DANAHER CORPORATION | 119,922 | $27.53M | 0.5% | $183.00 | +33.3% | COM | 235851102 |
| INSP | INSPIRE MED SYS INC | 148,478 | $27.52M | 0.5% | $156.51 | +24.0% | COM | 457730109 |
| VEEV | VEEVA SYS INC | 127,575 | $26.82M | 0.5% | $197.26 | +11.5% | CL A COM | 922475108 |
| ANNX | ANNEXON INC | 5,157,290 | $26.46M | 0.5% | $5.18 | +18.8% | COM | 03589W102 |
| — | VERONA PHARMA PLC | 568,955 | $26.42M | 0.5% | $19.12 | — | SPONSORED ADS | 925050106 |
| MRK | MERCK & CO INC | 264,226 | $26.29M | 0.5% | $99.67 | -1.0% | COM | 58933Y105 |
| — | SAGE THERAPEUTICS INC | 4,460,693 | $24.22M | 0.5% | $77.40 | — | COM | 78667J108 |
| MOH | MOLINA HEALTHCARE INC | 82,151 | $23.91M | 0.5% | $248.63 | +24.2% | COM | 60855R100 |
| AMGN | AMGEN INC | 89,240 | $23.26M | 0.4% | $268.25 | +6.6% | COM | 031162100 |
| NTRA | NATERA INC | 145,676 | $23.06M | 0.4% | $50.22 | +190.0% | COM | 632307104 |
| STE | STERIS PLC | 109,887 | $22.59M | 0.4% | $219.91 | -1.1% | SHS USD | G8473T100 |
| REGN | REGENERON PHARMACEUTICALS | 31,412 | $22.38M | 0.4% | $857.89 | -2.7% | COM | 75886F107 |
| ESPR | ESPERION THERAPEUTICS INC NE | 9,944,064 | $21.88M | 0.4% | $19.94 | -88.3% | COM | 29664W105 |
| BMRN | BIOMARIN PHARMACEUTICAL INC | 329,021 | $21.63M | 0.4% | $85.01 | -21.2% | COM | 09061G101 |
| BRKR | BRUKER CORP | 359,588 | $21.08M | 0.4% | $58.77 | 0.0% | COM | 116794108 |
| SRPT | SAREPTA THERAPEUTICS INC | 171,317 | $20.83M | 0.4% | $100.56 | +21.9% | COM | 803607100 |
| CSTL | CASTLE BIOSCIENCES INC | 745,982 | $19.88M | 0.4% | $31.14 | -2.2% | COM | 14843C105 |
| PRVA | PRIVIA HEALTH GROUP INC | 953,164 | $18.63M | 0.4% | $31.57 | -37.2% | COM | 74276R102 |
| HCA | HCA HEALTHCARE INC | 61,883 | $18.57M | 0.4% | $142.65 | +142.7% | COM | 40412C101 |
| BDTX | BLACK DIAMOND THERAPEUTICS I | 8,517,839 | $18.23M | 0.4% | $11.28 | -74.6% | COM | 09203E105 |
| HOLX | HOLOGIC INC | 247,886 | $17.87M | 0.3% | $59.24 | +31.9% | COM | 436440101 |
| INSM | INSMED INC | 258,483 | $17.85M | 0.3% | $28.84 | +149.7% | COM PAR $.01 | 457669307 |
| COR | CENCORA INC | 77,522 | $17.42M | 0.3% | $190.39 | +22.4% | COM | 03073E105 |
| EHC | ENCOMPASS HEALTH CORP | 188,522 | $17.41M | 0.3% | $94.80 | +2.7% | COM | 29261A100 |
| NEO | NEOGENOMICS INC | 1,055,796 | $17.4M | 0.3% | $15.29 | +1.6% | COM NEW | 64049M209 |
| ELV | ELEVANCE HEALTH INC | 38,343 | $14.14M | 0.3% | $341.23 | +19.9% | COM | 036752103 |
| THC | TENET HEALTHCARE CORP | 110,230 | $13.91M | 0.3% | $145.83 | +2.0% | COM NEW | 88033G407 |
| GPCR | STRUCTURE THERAPEUTICS INC | 485,050 | $13.15M | 0.3% | $42.02 | — | SPONSORD ADS | 86366E106 |
| EVH | EVOLENT HEALTH INC | 1,113,658 | $12.53M | 0.2% | $23.44 | -25.0% | CL A | 30050B101 |
| SIBN | SI-BONE INC | 880,979 | $12.35M | 0.2% | $17.88 | -24.7% | COM | 825704109 |
| TMDX | TRANSMEDICS GROUP INC | 192,718 | $12.02M | 0.2% | $30.57 | +204.5% | COM | 89377M109 |
| BIO | BIO RAD LABS INC | 33,551 | $11.02M | 0.2% | $467.64 | -27.4% | CL A | 090572207 |
| MCK | MCKESSON CORP | 19,315 | $11.01M | 0.2% | $521.49 | +6.9% | COM | 58155Q103 |
| PHR | PHREESIA INC | 405,693 | $10.21M | 0.2% | $34.11 | -37.4% | COM | 71944F106 |
| AXSM | AXSOME THERAPEUTICS INC | 118,930 | $10.06M | 0.2% | $56.28 | +63.4% | COM | 05464T104 |
| CRL | CHARLES RIV LABS INTL INC | 50,327 | $9.29M | 0.2% | $236.25 | -18.5% | COM | 159864107 |
| GKOS | GLAUKOS CORP | 60,875 | $9.128M | 0.2% | $93.28 | +47.7% | COM | 377322102 |
| IQV | IQVIA HLDGS INC | 44,833 | $8.81M | 0.2% | $229.76 | -8.2% | COM | 46266C105 |
| ABBV | ABBVIE INC | 45,259 | $8.043M | 0.2% | $156.52 | +13.4% | COM | 00287Y109 |
| FATE | FATE THERAPEUTICS INC | 4,839,779 | $7.986M | 0.2% | $40.00 | -93.7% | COM | 31189P102 |
| JNJ | JOHNSON & JOHNSON | 54,557 | $7.89M | 0.2% | $150.78 | -0.8% | COM | 478160104 |
| HUM | HUMANA INC | 28,367 | $7.197M | 0.1% | $395.71 | -33.4% | COM | 444859102 |
| ALT | ALTIMMUNE INC | 945,446 | $6.817M | 0.1% | $7.23 | +5.6% | COM NEW | 02155H200 |
| ASTH | ASTRANA HEALTH INC | 205,239 | $6.471M | 0.1% | $39.76 | +19.4% | COM NEW | 03763A207 |
| ONC | BEIGENE LTD | 34,229 | $6.322M | 0.1% | $206.58 | — | SPONSORED ADR | 07725L102 |
| TERN | TERNS PHARMACEUTICALS INC | 1,061,753 | $5.882M | 0.1% | $8.20 | -17.4% | COM | 880881107 |
| ILMN | ILLUMINA INC | 43,703 | $5.84M | 0.1% | $276.89 | -48.6% | COM | 452327109 |
| WAY | WAYSTAR HLDG CORP | 157,898 | $5.795M | 0.1% | $22.11 | +39.0% | COM | 946784105 |
| LEGN | LEGEND BIOTECH CORP | 167,341 | $5.445M | 0.1% | $45.72 | — | SPONSORED ADS | 52490G102 |
| CNC | CENTENE CORP DEL | 86,456 | $5.238M | 0.1% | $66.06 | -5.6% | COM | 15135B101 |
| GILD | GILEAD SCIENCES INC | 48,429 | $4.473M | 0.1% | $64.29 | +35.3% | COM | 375558103 |
| OMCL | OMNICELL COM | 94,740 | $4.218M | 0.1% | $80.67 | -44.3% | COM | 68213N109 |
| MASI | MASIMO CORP | 24,166 | $3.995M | 0.1% | $157.91 | 0.0% | COM | 574795100 |
| TXG | 10X GENOMICS INC | 270,728 | $3.888M | 0.1% | $84.17 | -81.3% | CL A COM | 88025U109 |
| PFE | PFIZER INC | 141,560 | $3.756M | 0.1% | $26.02 | -3.5% | COM | 717081103 |
| SPY | SPDR S&P 500 ETF TR | 5,660 | $3.317M | 0.1% | $586.08 | — | TR UNIT | 78462F103 |
| SMMT | SUMMIT THERAPEUTICS INC | 170,594 | $3.044M | 0.1% | $17.36 | +11.7% | COM | 86627T108 |
| BTSG | BRIGHTSPRING HEALTH SVCS INC | 174,152 | $2.966M | 0.1% | $17.29 | 0.0% | COM | 10950A106 |
| CAH | CARDINAL HEALTH INC | 22,298 | $2.637M | 0.1% | $98.91 | +16.1% | COM | 14149Y108 |
| RXRX | RECURSION PHARMACEUTICALS IN | 377,806 | $2.554M | 0.0% | $10.66 | -36.9% | CL A | 75629V104 |
| AZN | ASTRAZENECA PLC | 35,700 | $2.339M | 0.0% | $70.51 | — | SPONSORED ADR | 046353108 |
| BMY | BRISTOL-MYERS SQUIBB CO | 38,113 | $2.156M | 0.0% | $43.95 | +19.6% | COM | 110122108 |
| — | ACCOLADE INC | 615,509 | $2.105M | 0.0% | $27.70 | — | COM | 00437E102 |
| ZTS | ZOETIS INC | 9,779 | $1.593M | 0.0% | $175.67 | +0.4% | CL A | 98978V103 |
| RDY | DR REDDYS LABS LTD | 97,900 | $1.546M | 0.0% | $23.30 | — | ADR | 256135203 |
| DOCS | DOXIMITY INC | 27,911 | $1.49M | 0.0% | $36.02 | +35.9% | CL A | 26622P107 |
| TEVA | TEVA PHARMACEUTICAL INDS LTD | 60,598 | $1.336M | 0.0% | $14.28 | — | SPONSORED ADS | 881624209 |
| RYTM | RHYTHM PHARMACEUTICALS INC | 23,596 | $1.321M | 0.0% | $36.68 | +50.6% | COM | 76243J105 |
| GOOG | ALPHABET INC | 6,000 | $1.143M | 0.0% | $111.55 | +57.5% | CAP STK CL C | 02079K107 |
| PCVX | VAXCYTE INC | 12,038 | $985K | 0.0% | $49.07 | +102.4% | COM | 92243G108 |
| CERT | CERTARA INC | 92,129 | $981K | 0.0% | $16.83 | -35.5% | COM | 15687V109 |
| CVS | CVS HEALTH CORP | 21,844 | $981K | 0.0% | $65.07 | -17.6% | COM | 126650100 |
| BNTX | BIONTECH SE | 8,332 | $949K | 0.0% | $118.77 | — | SPONSORED ADS | 09075V102 |
| PTGX | PROTAGONIST THERAPEUTICS INC | 23,718 | $916K | 0.0% | $31.00 | +40.6% | COM | 74366E102 |
| GDX | VANECK ETF TRUST | 26,200 | $888K | 0.0% | $33.91 | — | GOLD MINERS ETF | 92189F106 |
| AMRX | AMNEAL PHARMACEUTICALS INC | 100,414 | $795K | 0.0% | $6.42 | +30.8% | COM STK CL A | 03168L105 |
| KRYS | KRYSTAL BIOTECH INC | 5,047 | $791K | 0.0% | $83.16 | +113.3% | COM | 501147102 |
| NAMS | NEWAMSTERDAM PHARMA COMPANY | 25,000 | $643K | 0.0% | $20.03 | +6.1% | ORDINARY SHARES | N62509109 |
| ARQT | ARCUTIS BIOTHERAPEUTICS INC | 39,500 | $550K | 0.0% | $9.50 | +15.3% | COM | 03969K108 |
| VKTX | VIKING THERAPEUTICS INC | 12,939 | $521K | 0.0% | $46.27 | +23.2% | COM | 92686J106 |
| CYTK | CYTOKINETICS INC | 10,941 | $515K | 0.0% | $37.85 | +37.2% | COM NEW | 23282W605 |
| BIIB | BIOGEN INC | 2,652 | $406K | 0.0% | $249.86 | -32.5% | COM | 09062X103 |
| TVTX | TRAVERE THERAPEUTICS INC | 23,100 | $402K | 0.0% | $10.42 | +69.8% | COM | 89422G107 |
| QURE | UNIQURE NV | 22,500 | $397K | 0.0% | $8.63 | 0.0% | SHS | N90064101 |
| ASND | ASCENDIS PHARMA A/S | 2,500 | $344K | 0.0% | $137.67 | — | SPONSORED ADR | 04351P101 |
| ZLAB | ZAI LAB LTD | 13,000 | $340K | 0.0% | $26.19 | — | ADR | 98887Q104 |
| MDGL | MADRIGAL PHARMACEUTICALS INC | 1,100 | $339K | 0.0% | $235.71 | +19.3% | COM | 558868105 |
| — | MERUS N V | 8,000 | $336K | 0.0% | $18.01 | — | COM | N5749R100 |
| XENE | XENON PHARMACEUTICALS INC | 8,200 | $321K | 0.0% | $39.75 | +4.0% | COM | 98420N105 |
| DNLI | DENALI THERAPEUTICS INC | 15,700 | $320K | 0.0% | $24.79 | +3.3% | COM | 24823R105 |
| ADMA | ADMA BIOLOGICS INC | 16,900 | $290K | 0.0% | $5.47 | +244.2% | COM | 000899104 |
| BBIO | BRIDGEBIO PHARMA INC | 10,400 | $285K | 0.0% | $12.16 | +112.5% | COM | 10806X102 |
| ROIV | ROIVANT SCIENCES LTD | 24,000 | $284K | 0.0% | $11.82 | 0.0% | SHS | G76279101 |
| — | BLUEPRINT MEDICINES CORP | 3,200 | $279K | 0.0% | $94.86 | — | COM | 09627Y109 |
| MLTX | MOONLAKE IMMUNOTHERAPEUTICS | 4,400 | $238K | 0.0% | $54.24 | -5.9% | CLASS A ORD | 61559X104 |
| ACLX | ARCELLX INC | 3,000 | $230K | 0.0% | $66.59 | +29.7% | COMMON STOCK | 03940C100 |
| GRMN | GARMIN LTD | 1,050 | $217K | 0.0% | $127.62 | +50.8% | SHS | H2906T109 |
| MLYS | MINERALYS THERAPEUTICS INC | 16,499 | $203K | 0.0% | $12.47 | +4.9% | COM | 603170101 |
| PTCT | PTC THERAPEUTICS INC | 3,800 | $172K | 0.0% | $42.80 | 0.0% | COM | 69366J200 |
| OCS | OCULIS HOLDING AG | 10,000 | $170K | 0.0% | $15.74 | 0.0% | ORDINARY SHARES | H5870P102 |
| BIDU | BAIDU INC | 2,000 | $169K | 0.0% | $105.28 | — | SPON ADR REP A | 056752108 |
| RARE | ULTRAGENYX PHARMACEUTICAL IN | 4,000 | $168K | 0.0% | $42.70 | +16.2% | COM | 90400D108 |
| KNSA | KINIKSA PHARMACEUTICALS INTL | 8,100 | $160K | 0.0% | $22.82 | 0.0% | ORD SHS CL A | G52694109 |
| NRIX | NURIX THERAPEUTICS INC | 8,000 | $151K | 0.0% | $22.65 | +1.2% | COM | 67080M103 |
| VCYT | VERACYTE INC | 3,600 | $143K | 0.0% | $28.13 | +34.6% | COM | 92337F107 |
| KURA | KURA ONCOLOGY INC | 13,600 | $118K | 0.0% | $20.48 | -29.7% | COM | 50127T109 |
| — | MODERNA INC | 150 | $110K | 0.0% | — | — | Call | 60770K907 |
| ORCL | ORACLE CORP | 654 | $109K | 0.0% | $114.45 | +53.6% | COM | 68389X105 |
| A | AGILENT TECHNOLOGIES INC | 806 | $108K | 0.0% | $127.78 | +6.4% | COM | 00846U101 |
| NVDA | NVIDIA CORPORATION | 751 | $101K | 0.0% | $97.08 | +41.9% | COM | 67066G104 |
| AUTL | AUTOLUS THERAPEUTICS PLC | 41,500 | $97,525 | 0.0% | $5.83 | — | SPON ADS | 05280R100 |
| MSFT | MICROSOFT CORP | 203 | $85,565 | 0.0% | $372.82 | +13.3% | COM | 594918104 |
| QCOM | QUALCOMM INC | 447 | $68,668 | 0.0% | $133.12 | +19.8% | COM | 747525103 |
| MTD | METTLER TOLEDO INTERNATIONAL | 42 | $51,395 | 0.0% | $1170.94 | +11.4% | COM | 592688105 |
| LH | LABCORP HOLDINGS INC | 216 | $49,533 | 0.0% | $202.00 | +12.1% | COM SHS | 504922105 |
| TEM | TEMPUS AI INC | 237 | $8,001 | 0.0% | $30.66 | +61.3% | CL A | 88023B103 |