Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
BIIB	BIOGEN INC	100,000	$21.61M	2.8%	—	—	CALL	09062X103
INSM	INSMED INC	118,800	$12.67M	1.7%	—	—	COM PAR $.01	457669307
RYTM	RHYTHM PHARMACEUTICALS INC	80,400	$8.927M	1.2%	—	—	COM	76243J105
LRCX	LAM RESEARCH CORP	18,470	$8.004M	1.0%	—	—	COM NEW	512807306
AMAT	APPLIED MATLS INC	11,040	$7.982M	1.0%	—	—	COM	038222105
IDYA	IDEAYA BIOSCIENCES INC	196,408	$7.32M	1.0%	—	—	COM	45166A102
NVCT	NUVECTIS PHARMA INC	382,945	$7.042M	0.9%	—	—	COM	67080T108
HRMY	HARMONY BIOSCIENCES HLDGS IN	176,663	$6.432M	0.8%	—	—	COM	413197104
VST	VISTRA CORP	29,450	$4.672M	0.6%	—	—	COM	92840M102
TLN	TALEN ENERGY CORP	12,135	$4.663M	0.6%	—	—	COM	87422Q109
CLOU	GLOBAL X FDS	195,900	$4.455M	0.6%	—	—	CLOUD COMPUTNG	37954Y442
AVTX	AVALO THERAPEUTICS INC	232,294	$4.293M	0.6%	—	—	COM NEW	05338F306
PRAX	PRAXIS PRECISION MEDICINES I	12,500	$4.185M	0.5%	—	—	CALL	74006W207
CABA	CABALETTA BIO INC	1,329,012	$4.133M	0.5%	—	—	COM	12674W109
BBOT	BRIDGEBIO ONCOLOGY THERAPEUT	460,985	$3.513M	0.5%	—	—	COM NEW	107924102
PRQR	PROQR THRAPEUTICS N V	1,757,458	$3.269M	0.4%	—	—	SHS EURO	N71542109
ALNY	ALNYLAM PHARMACEUTICALS INC	10,800	$3.251M	0.4%	—	—	COM	02043Q107
LRMR	LARIMAR THERAPEUTICS INC	926,004	$2.824M	0.4%	—	—	COM	517125100
IMMX	IMMIX BIOPHARMA INC	270,000	$2.784M	0.4%	—	—	COM	45258H106
ABVX	ABIVAX SA	20,000	$2.665M	0.3%	—	—	PUT	00370M103
CEG	CONSTELLATION ENERGY CORP	9,850	$2.446M	0.3%	—	—	COM	21037T109
TENX	TENAX THERAPEUTICS INC	127,600	$1.857M	0.2%	—	—	CALL	88032L605
TSHA	TAYSHA GENE THERAPIES INC	250,000	$1.702M	0.2%	—	—	COM SHS	877619106
IKT	INHIBIKASE THERAPEUTICS INC	649,309	$1.318M	0.2%	—	—	COM NEW	45719W205
ORIC	ORIC PHARMACEUTICALS INC	100,000	$1.083M	0.1%	—	—	CALL	68622P109
TRAX	FIRST TRACKS BIOTHERAPEUTICS	27,876	$561K	0.1%	—	—	ORD SHS	337185102
TRAW	TRAWS PHARMA INC	398,486	$336K	0.0%	—	—	COM NEW	68232V884

Increased Positions (32)

TEVA TEVA PHARMACEUTICAL INDS LTD 6.6%

Value $50.82M (+48.4%) Shares 1,500,082 (+31.9%) Est. Cost — Unrealized —

CYTK CYTOKINETICS INC 2.4%

Value $18.74M (+614.1%) Shares 219,987 (+452.5%) Est. Cost — Unrealized —

BMRN BIOMARIN PHARMACEUTICAL INC 2.5%

Value $18.8M (+137.9%) Shares 328,550 (+134.8%) Est. Cost — Unrealized —

HELP CYBIN INC 1.4%

Value $10.71M (+126.1%) Shares 1,620,753 (+64.2%) Est. Cost — Unrealized —

MAZE MAZE THERAPEUTICS INC 1.6%

Value $12.46M (+83.6%) Shares 417,564 (+83.7%) Est. Cost — Unrealized —

SNDX SYNDAX PHARMACEUTICALS INC 2.9%

Value $22.18M (+31.0%) Shares 1,014,606 (+40.0%) Est. Cost — Unrealized —

MDGL MADRIGAL PHARMACEUTICALS INC 1.2%

Value $9.353M (+97.7%) Shares 17,419 (+92.7%) Est. Cost — Unrealized —

BIIB BIOGEN INC 2.7%

Value $20.88M (+23.1%) Shares 96,626 (+4.4%) Est. Cost — Unrealized —

BIOA BIOAGE LABS INC 0.7%

Value $5.237M (+246.1%) Shares 213,671 (+147.0%) Est. Cost — Unrealized —

PRLD PRELUDE THERAPEUTICS INC 0.7%

Value $5.436M (+184.7%) Shares 1,019,832 (+82.7%) Est. Cost — Unrealized —

CLYM CLIMB BIO INC 0.8%

Value $6.308M (+119.7%) Shares 483,747 (+15.4%) Est. Cost — Unrealized —

MLYS MINERALYS THERAPEUTICS INC 5.2%

Value $39.66M (+9.3%) Shares 1,469,971 (+9.7%) Est. Cost — Unrealized —

ACAD ACADIA PHARMACEUTICALS INC 1.2%

Value $9.02M (+58.2%) Shares 356,534 (+39.2%) Est. Cost — Unrealized —

MSLE SATELLOS BIOSCIENCE INC 0.7%

Value $5.074M (+84.2%) Shares 652,590 (+33.4%) Est. Cost — Unrealized —

CTMX CYTOMX THERAPEUTICS INC. 0.4%

Value $3.296M (+218.8%) Shares 879,000 (+299.5%) Est. Cost — Unrealized —

NVS NOVARTIS AG 1.0%

Value $7.833M (+38.6%) Shares 50,000 (+35.1%) Est. Cost — Unrealized —

VOR VOR BIOPHARMA INC 1.0%

Value $7.666M (+33.5%) Shares 416,417 (+29.4%) Est. Cost — Unrealized —

GENB GENERATE BIOMEDICINES INC 0.5%

Value $4.133M (+78.7%) Shares 245,000 (+32.4%) Est. Cost — Unrealized —

COGT COGENT BIOSCIENCES INC 2.3%

Value $17.78M (+10.9%) Shares 459,340 (+10.3%) Est. Cost — Unrealized —

MRK MERCK & CO INC 1.0%

Value $7.53M (+28.8%) Shares 58,600 (+20.6%) Est. Cost — Unrealized —

PALI PALISADE BIO INC 0.6%

Value $4.717M (+55.5%) Shares 2,257,106 (+30.2%) Est. Cost — Unrealized —

ZBIO ZENAS BIOPHARMA INC 0.8%

Value $5.859M (+39.8%) Shares 230,834 (+7.7%) Est. Cost — Unrealized —

PFE PFIZER INC 0.9%

Value $6.887M (+31.9%) Shares 286,000 (+53.8%) Est. Cost — Unrealized —

DYN DYNE THERAPEUTICS INC 0.6%

Value $4.433M (+52.3%) Shares 199,594 (+24.3%) Est. Cost — Unrealized —

ORIC ORIC PHARMACEUTICALS INC 1.1%

Value $8.155M (+19.7%) Shares 752,983 (+40.1%) Est. Cost — Unrealized —

IRON DISC MEDICINE INC 0.6%

Value $4.647M (+35.8%) Shares 63,538 (+18.7%) Est. Cost — Unrealized —

CTNM CONTINEUM THERAPEUTICS INC 0.4%

Value $3.007M (+32.7%) Shares 183,475 (+5.8%) Est. Cost — Unrealized —

SVRA SAVARA INC 0.6%

Value $4.658M (+15.4%) Shares 756,164 (+2.3%) Est. Cost — Unrealized —

VSTM VERASTEM INC 0.3%

Value $2.417M (+32.7%) Shares 632,632 (+84.1%) Est. Cost — Unrealized —

FBRX FORTE BIOSCIENCES INC 0.7%

Value $5.306M (+10.7%) Shares 249,693 (+35.0%) Est. Cost — Unrealized —

IMTX IMMATICS N.V 1.0%

Value $7.294M (+6.5%) Shares 720,057 (+3.4%) Est. Cost — Unrealized —

WVE WAVE LIFE SCIENCES LTD 0.5%

Value $3.708M (-6.7%) Shares 638,272 (+16.4%) Est. Cost — Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
TEVA	TEVA PHARMACEUTICAL INDS LTD	1,500,082 (+31.9%)	$50.82M (+48.4%)	6.6%	—	—	SPONSORED ADS	881624209
CYTK	CYTOKINETICS INC	219,987 (+452.5%)	$18.74M (+614.1%)	2.4%	—	—	COM NEW	23282W605
BMRN	BIOMARIN PHARMACEUTICAL INC	328,550 (+134.8%)	$18.8M (+137.9%)	2.5%	—	—	COM	09061G101
HELP	CYBIN INC	1,620,753 (+64.2%)	$10.71M (+126.1%)	1.4%	—	—	COM NEW	23256X407
MAZE	MAZE THERAPEUTICS INC	417,564 (+83.7%)	$12.46M (+83.6%)	1.6%	—	—	COM	578784100
SNDX	SYNDAX PHARMACEUTICALS INC	1,014,606 (+40.0%)	$22.18M (+31.0%)	2.9%	—	—	COM	87164F105
MDGL	MADRIGAL PHARMACEUTICALS INC	17,419 (+92.7%)	$9.353M (+97.7%)	1.2%	—	—	COM	558868105
BIIB	BIOGEN INC	96,626 (+4.4%)	$20.88M (+23.1%)	2.7%	—	—	COM	09062X103
BIOA	BIOAGE LABS INC	213,671 (+147.0%)	$5.237M (+246.1%)	0.7%	—	—	COM	09077V100
PRLD	PRELUDE THERAPEUTICS INC	1,019,832 (+82.7%)	$5.436M (+184.7%)	0.7%	—	—	COM	74065P101
CLYM	CLIMB BIO INC	483,747 (+15.4%)	$6.308M (+119.7%)	0.8%	—	—	COM	28658R106
MLYS	MINERALYS THERAPEUTICS INC	1,469,971 (+9.7%)	$39.66M (+9.3%)	5.2%	—	—	COM	603170101
ACAD	ACADIA PHARMACEUTICALS INC	356,534 (+39.2%)	$9.02M (+58.2%)	1.2%	—	—	COM	004225108
MSLE	SATELLOS BIOSCIENCE INC	652,590 (+33.4%)	$5.074M (+84.2%)	0.7%	—	—	COM	80401L803
CTMX	CYTOMX THERAPEUTICS INC.	879,000 (+299.5%)	$3.296M (+218.8%)	0.4%	—	—	COM	23284F105
NVS	NOVARTIS AG	50,000 (+35.1%)	$7.833M (+38.6%)	1.0%	—	—	SPONSORED ADR	66987V109
VOR	VOR BIOPHARMA INC	416,417 (+29.4%)	$7.666M (+33.5%)	1.0%	—	—	COM NEW	929033207
GENB	GENERATE BIOMEDICINES INC	245,000 (+32.4%)	$4.133M (+78.7%)	0.5%	—	—	COM SHS	370920100
COGT	COGENT BIOSCIENCES INC	459,340 (+10.3%)	$17.78M (+10.9%)	2.3%	—	—	COM	19240Q201
MRK	MERCK & CO INC	58,600 (+20.6%)	$7.53M (+28.8%)	1.0%	—	—	COM	58933Y105
PALI	PALISADE BIO INC	2,257,106 (+30.2%)	$4.717M (+55.5%)	0.6%	—	—	COM	696389402
ZBIO	ZENAS BIOPHARMA INC	230,834 (+7.7%)	$5.859M (+39.8%)	0.8%	—	—	COM	98937L105
PFE	PFIZER INC	286,000 (+53.8%)	$6.887M (+31.9%)	0.9%	—	—	COM	717081103
DYN	DYNE THERAPEUTICS INC	199,594 (+24.3%)	$4.433M (+52.3%)	0.6%	—	—	COM	26818M108
ORIC	ORIC PHARMACEUTICALS INC	752,983 (+40.1%)	$8.155M (+19.7%)	1.1%	—	—	COM	68622P109
IRON	DISC MEDICINE INC	63,538 (+18.7%)	$4.647M (+35.8%)	0.6%	—	—	COM	254604101
CTNM	CONTINEUM THERAPEUTICS INC	183,475 (+5.8%)	$3.007M (+32.7%)	0.4%	—	—	CL A	21217B100
SVRA	SAVARA INC	756,164 (+2.3%)	$4.658M (+15.4%)	0.6%	—	—	COM	805111101
VSTM	VERASTEM INC	632,632 (+84.1%)	$2.417M (+32.7%)	0.3%	—	—	COM NEW	92337C203
FBRX	FORTE BIOSCIENCES INC	249,693 (+35.0%)	$5.306M (+10.7%)	0.7%	—	—	COM NEW	34962G208
IMTX	IMMATICS N.V	720,057 (+3.4%)	$7.294M (+6.5%)	1.0%	—	—	SHS	N44445109
WVE	WAVE LIFE SCIENCES LTD	638,272 (+16.4%)	$3.708M (-6.7%)	0.5%	—	—	SHS	Y95308105

Exited Positions (18)

FOLD AMICUS THERAPEUTIC 1.1%

Value $8.725M Shares 603,377 Est. Cost — Unrealized —

CLBT CELLEBRITE DI LTD 1.1%

Value $8.702M Shares 631,521 Est. Cost — Unrealized —

APLS APELLIS PHARMACEUTICALS INC 1.1%

Value $8.646M Shares 214,914 Est. Cost — Unrealized —

PANW PALO ALTO NETWORKS INC 1.1%

Value $8.465M Shares 52,800 Est. Cost — Unrealized —

CAMT CAMTEK LTD 1.0%

Value $8.038M Shares 53,020 Est. Cost — Unrealized —

SLNO SOLENO THERAPEUTICS INC 0.9%

Value $7.241M Shares 216,281 Est. Cost — Unrealized —

AMZN AMAZON COM INC 0.9%

Value $6.652M Shares 31,940 Est. Cost — Unrealized —

AAOI APPLIED OPTOELECTRONICS INC 0.8%

Value $6.209M Shares 73,400 Est. Cost — Unrealized —

ENPH ENPHASE ENERGY INC 0.7%

Value $5.385M Shares 142,419 Est. Cost — Unrealized —

ZIM ZIM INTEGRATED SHIPPING SERV 0.4%

Value $2.792M Shares 105,950 Est. Cost — Unrealized —

SEDG SOLAREDGE TECHNOLOGIES INC 0.4%

Value $2.697M Shares 52,836 Est. Cost — Unrealized —

IBIT ISHARES BITCOIN TRUST ETF 0.3%

Value $2.286M Shares 59,505 Est. Cost — Unrealized —

ASND ASCENDIS PHARMA A/S 0.2%

Value $1.83M Shares 8,000 Est. Cost — Unrealized —

OLMA OLEMA PHARMACEUTICALS INC 0.2%

Value $1.491M Shares 100,000 Est. Cost — Unrealized —

BMY BRISTOL-MYERS SQUIBB CO 0.1%

Value $1.061M Shares 17,500 Est. Cost — Unrealized —

NICE NICE LTD 0.1%

Value $619K Shares 5,611 Est. Cost — Unrealized —

DTIL PRECISION BIOSCIENCES INC 0.0%

Value $220K Shares 40,000 Est. Cost — Unrealized —

FHTX FOGHORN THERAPEUTICS INC 0.0%

Value $58,431 Shares 12,224 Est. Cost — Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
FOLD	AMICUS THERAPEUTIC	603,377	$8.725M	1.1%	—	—	—	03152W109
CLBT	CELLEBRITE DI LTD	631,521	$8.702M	1.1%	—	—	—	M2197Q107
APLS	APELLIS PHARMACEUTICALS INC	214,914	$8.646M	1.1%	—	—	—	03753U106
PANW	PALO ALTO NETWORKS INC	52,800	$8.465M	1.1%	—	—	—	697435105
CAMT	CAMTEK LTD	53,020	$8.038M	1.0%	—	—	—	M20791105
SLNO	SOLENO THERAPEUTICS INC	216,281	$7.241M	0.9%	—	—	—	834203309
AMZN	AMAZON COM INC	31,940	$6.652M	0.9%	—	—	—	023135106
AAOI	APPLIED OPTOELECTRONICS INC	73,400	$6.209M	0.8%	—	—	—	03823U102
ENPH	ENPHASE ENERGY INC	142,419	$5.385M	0.7%	—	—	—	29355A107
ZIM	ZIM INTEGRATED SHIPPING SERV	105,950	$2.792M	0.4%	—	—	—	M9T951109
SEDG	SOLAREDGE TECHNOLOGIES INC	52,836	$2.697M	0.4%	—	—	—	83417M104
IBIT	ISHARES BITCOIN TRUST ETF	59,505	$2.286M	0.3%	—	—	—	46438F101
ASND	ASCENDIS PHARMA A/S	8,000	$1.83M	0.2%	—	—	—	04351P101
OLMA	OLEMA PHARMACEUTICALS INC	100,000	$1.491M	0.2%	—	—	CALL	68062P106
BMY	BRISTOL-MYERS SQUIBB CO	17,500	$1.061M	0.1%	—	—	—	110122108
NICE	NICE LTD	5,611	$619K	0.1%	—	—	—	653656108
DTIL	PRECISION BIOSCIENCES INC	40,000	$220K	0.0%	—	—	—	74019P207
FHTX	FOGHORN THERAPEUTICS INC	12,224	$58,431	0.0%	—	—	—	344174107

Decreased Positions (29)

NVMI NOVA LTD 1.8%

Value $13.67M (-41.0%) Shares 25,169 (-52.8%) Est. Cost — Unrealized —

CYTK CYTOKINETICS INC 1.1%

Value $8.519M (-50.2%) Shares 100,000 (-61.4%) Est. Cost — Unrealized —

ORA ORMAT TECHNOLOGIES INC 0.4%

Value $3.051M (-60.1%) Shares 28,015 (-59.0%) Est. Cost — Unrealized —

BCRX BIOCRYST PHARMACEUTICALS INC 0.6%

Value $4.221M (-48.8%) Shares 422,051 (-51.3%) Est. Cost — Unrealized —

RARE ULTRAGENYX PHARMACEUTICAL IN 2.6%

Value $19.65M (+15.9%) Shares 588,494 (-27.3%) Est. Cost — Unrealized —

TSEM TOWER SEMICONDUCTOR LTD 3.7%

Value $28.22M (+10.3%) Shares 108,265 (-25.7%) Est. Cost — Unrealized —

BHVN BIOHAVEN LTD 0.3%

Value $2.447M (-51.3%) Shares 164,437 (-72.3%) Est. Cost — Unrealized —

TRVI TREVI THERAPEUTICS INC 1.2%

Value $9.307M (+35.9%) Shares 499,029 (-13.1%) Est. Cost — Unrealized —

XBI SPDR SERIES TRUST 3.1%

Value $23.74M (-7.1%) Shares 150,000 (-25.0%) Est. Cost — Unrealized —

UPB UPSTREAM BIO INC 0.2%

Value $1.52M (-52.8%) Shares 219,700 (-38.6%) Est. Cost — Unrealized —

EVMN EVOMMUNE INC 0.0%

Value $301K (-83.3%) Shares 22,632 (-71.1%) Est. Cost — Unrealized —

GSK GSK PLC 0.7%

Value $5.347M (-20.6%) Shares 102,000 (-16.4%) Est. Cost — Unrealized —

LLY ELI LILLY & CO 1.3%

Value $9.643M (+16.0%) Shares 8,040 (-11.1%) Est. Cost — Unrealized —

CLDX CELLDEX THERAPEUTICS INC NEW 1.2%

Value $8.963M (+16.0%) Shares 240,868 (-1.1%) Est. Cost — Unrealized —

STTK SHATTUCK LABS INC 0.1%

Value $600K (-66.8%) Shares 86,461 (-69.2%) Est. Cost — Unrealized —

KOD KODIAK SCIENCES INC 0.4%

Value $3.187M (-27.2%) Shares 81,796 (-28.7%) Est. Cost — Unrealized —

RVMD REVOLUTION MEDICINES INC 0.5%

Value $4.195M (-21.7%) Shares 22,400 (-59.4%) Est. Cost — Unrealized —

XENE XENON PHARMACEUTICALS INC 0.8%

Value $6.338M (-14.2%) Shares 105,000 (-17.3%) Est. Cost — Unrealized —

GPCR STRUCTURE THERAPEUTICS INC 0.2%

Value $1.535M (-37.3%) Shares 28,600 (-43.7%) Est. Cost — Unrealized —

ACOG ALPHA COGNITION INC 0.5%

Value $3.941M (+26.5%) Shares 545,816 (-3.8%) Est. Cost — Unrealized —

ELDN ELEDON PHARMACEUTICALS INC 0.6%

Value $4.693M (-14.0%) Shares 1,191,187 (-32.8%) Est. Cost — Unrealized —

TNGX TANGO THERAPEUTICS INC 1.0%

Value $7.948M (+10.6%) Shares 254,250 (-26.0%) Est. Cost — Unrealized —

TENX TENAX THERAPEUTICS INC 0.2%

Value $1.749M (-19.6%) Shares 120,200 (-11.6%) Est. Cost — Unrealized —

VYGR VOYAGER THERAPEUTICS INC 0.2%

Value $1.496M (-17.5%) Shares 427,554 (-9.0%) Est. Cost — Unrealized —

RLAY RELAY THERAPEUTICS INC 0.6%

Value $4.375M (+7.7%) Shares 233,836 (-42.7%) Est. Cost — Unrealized —

ELVN ENLIVEN THERAPEUTICS INC 0.7%

Value $5.723M (-4.7%) Shares 112,765 (-26.4%) Est. Cost — Unrealized —

CRIS CURIS INC 0.1%

Value $1.034M (-5.3%) Shares 98,996 (-95.0%) Est. Cost — Unrealized —

OVID OVID THERAPEUTICS INC 0.5%

Value $3.64M (+1.0%) Shares 1,353,000 (-16.6%) Est. Cost — Unrealized —

CRVS CORVUS PHARMACEUTICALS INC 0.5%

Value $3.66M (+0.9%) Shares 244,961 (-1.2%) Est. Cost — Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
NVMI	NOVA LTD	25,169 (-52.8%)	$13.67M (-41.0%)	1.8%	—	—	COM	M7516K103
CYTK	CYTOKINETICS INC	100,000 (-61.4%)	$8.519M (-50.2%)	1.1%	—	—	CALL	23282W605
ORA	ORMAT TECHNOLOGIES INC	28,015 (-59.0%)	$3.051M (-60.1%)	0.4%	—	—	COM	686688102
BCRX	BIOCRYST PHARMACEUTICALS INC	422,051 (-51.3%)	$4.221M (-48.8%)	0.6%	—	—	COM	09058V103
RARE	ULTRAGENYX PHARMACEUTICAL IN	588,494 (-27.3%)	$19.65M (+15.9%)	2.6%	—	—	COM	90400D108
TSEM	TOWER SEMICONDUCTOR LTD	108,265 (-25.7%)	$28.22M (+10.3%)	3.7%	—	—	SHS NEW	M87915274
BHVN	BIOHAVEN LTD	164,437 (-72.3%)	$2.447M (-51.3%)	0.3%	—	—	COM	G1110E107
TRVI	TREVI THERAPEUTICS INC	499,029 (-13.1%)	$9.307M (+35.9%)	1.2%	—	—	COM	89532M101
XBI	SPDR SERIES TRUST	150,000 (-25.0%)	$23.74M (-7.1%)	3.1%	—	—	PUT	78464A870
UPB	UPSTREAM BIO INC	219,700 (-38.6%)	$1.52M (-52.8%)	0.2%	—	—	COM	91678A107
EVMN	EVOMMUNE INC	22,632 (-71.1%)	$301K (-83.3%)	0.0%	—	—	COM SHS	30054Y107
GSK	GSK PLC	102,000 (-16.4%)	$5.347M (-20.6%)	0.7%	—	—	SPONSORED ADR	37733W204
LLY	ELI LILLY & CO	8,040 (-11.1%)	$9.643M (+16.0%)	1.3%	—	—	COM	532457108
CLDX	CELLDEX THERAPEUTICS INC NEW	240,868 (-1.1%)	$8.963M (+16.0%)	1.2%	—	—	COM NEW	15117B202
STTK	SHATTUCK LABS INC	86,461 (-69.2%)	$600K (-66.8%)	0.1%	—	—	COM	82024L103
KOD	KODIAK SCIENCES INC	81,796 (-28.7%)	$3.187M (-27.2%)	0.4%	—	—	COM	50015M109
RVMD	REVOLUTION MEDICINES INC	22,400 (-59.4%)	$4.195M (-21.7%)	0.5%	—	—	COM	76155X100
XENE	XENON PHARMACEUTICALS INC	105,000 (-17.3%)	$6.338M (-14.2%)	0.8%	—	—	COM	98420N105
GPCR	STRUCTURE THERAPEUTICS INC	28,600 (-43.7%)	$1.535M (-37.3%)	0.2%	—	—	SPONSORED ADS	86366E106
ACOG	ALPHA COGNITION INC	545,816 (-3.8%)	$3.941M (+26.5%)	0.5%	—	—	COM NEW	02074J501
ELDN	ELEDON PHARMACEUTICALS INC	1,191,187 (-32.8%)	$4.693M (-14.0%)	0.6%	—	—	COM	28617K101
TNGX	TANGO THERAPEUTICS INC	254,250 (-26.0%)	$7.948M (+10.6%)	1.0%	—	—	COM	87583X109
TENX	TENAX THERAPEUTICS INC	120,200 (-11.6%)	$1.749M (-19.6%)	0.2%	—	—	COM NEW	88032L605
VYGR	VOYAGER THERAPEUTICS INC	427,554 (-9.0%)	$1.496M (-17.5%)	0.2%	—	—	COM	92915B106
RLAY	RELAY THERAPEUTICS INC	233,836 (-42.7%)	$4.375M (+7.7%)	0.6%	—	—	COM	75943R102
ELVN	ENLIVEN THERAPEUTICS INC	112,765 (-26.4%)	$5.723M (-4.7%)	0.7%	—	—	COM	29337E102
CRIS	CURIS INC	98,996 (-95.0%)	$1.034M (-5.3%)	0.1%	—	—	COM	231269309
OVID	OVID THERAPEUTICS INC	1,353,000 (-16.6%)	$3.64M (+1.0%)	0.5%	—	—	COM	690469101
CRVS	CORVUS PHARMACEUTICALS INC	244,961 (-1.2%)	$3.66M (+0.9%)	0.5%	—	—	COM	221015100

Unchanged Positions (17)

SNY SANOFI SA 1.5%

Value $11.5M Shares 269,515 Est. Cost — Unrealized —

NVO NOVO-NORDISK A S 0.8%

Value $5.785M Shares 120,677 Est. Cost — Unrealized —

ABBV ABBVIE INC 1.0%

Value $7.614M Shares 30,256 Est. Cost — Unrealized —

— SOLAREDGE TECHNOLOGIES INC 1.0%

Value $7.747M Shares 4,000,000 Est. Cost — Unrealized —

KURA KURA ONCOLOGY INC 0.4%

Value $3.237M Shares 295,039 Est. Cost — Unrealized —

SRRK SCHOLAR ROCK HLDG CORP 0.7%

Value $5.185M Shares 94,265 Est. Cost — Unrealized —

AZN ASTRAZENECA PLC 1.5%

Value $11.86M Shares 62,530 Est. Cost — Unrealized —

MDWD MEDIWOUND LTD 0.5%

Value $4.016M Shares 273,192 Est. Cost — Unrealized —

HOWL WEREWOLF THERAPEUTICS INC 0.0%

Value $226K Shares 626,810 Est. Cost — Unrealized —

JNJ JOHNSON & JOHNSON 1.0%

Value $7.322M Shares 28,831 Est. Cost — Unrealized —

PMN PROMIS NEUROSCIENCES INC 0.6%

Value $4.285M Shares 325,591 Est. Cost — Unrealized —

AMGN AMGEN INC 0.4%

Value $2.716M Shares 7,500 Est. Cost — Unrealized —

BBIO BRIDGEBIO PHARMA INC 2.4%

Value $18.27M Shares 245,346 Est. Cost — Unrealized —

SKYE SKYE BIOSCIENCE INC 0.1%

Value $471K Shares 678,928 Est. Cost — Unrealized —

ORGO ORGANOGENESIS HLDGS INC 0.2%

Value $1.337M Shares 550,000 Est. Cost — Unrealized —

TLT ISHARES TR 0.5%

Value $4.062M Shares 47,000 Est. Cost — Unrealized —

APRE APREA THERAPEUTICS INC 0.0%

Value $217K Shares 270,000 Est. Cost — Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
SNY	SANOFI SA	269,515	$11.5M	1.5%	—	—	SPONSORED ADR	80105N105
NVO	NOVO-NORDISK A S	120,677	$5.785M	0.8%	—	—	ADR	670100205
ABBV	ABBVIE INC	30,256	$7.614M	1.0%	—	—	COM	00287Y109
—	SOLAREDGE TECHNOLOGIES INC	4,000,000	$7.747M	1.0%	—	—	NOTE 2.250% 7/0	83417MAE4
KURA	KURA ONCOLOGY INC	295,039	$3.237M	0.4%	—	—	COM	50127T109
SRRK	SCHOLAR ROCK HLDG CORP	94,265	$5.185M	0.7%	—	—	COM	80706P103
AZN	ASTRAZENECA PLC	62,530	$11.86M	1.5%	—	—	ORD	G0593M107
MDWD	MEDIWOUND LTD	273,192	$4.016M	0.5%	—	—	SHS NEW	M68830112
HOWL	WEREWOLF THERAPEUTICS INC	626,810	$226K	0.0%	—	—	COM	95075A107
JNJ	JOHNSON & JOHNSON	28,831	$7.322M	1.0%	—	—	COM	478160104
PMN	PROMIS NEUROSCIENCES INC	325,591	$4.285M	0.6%	—	—	COM SHS	74346M505
AMGN	AMGEN INC	7,500	$2.716M	0.4%	—	—	COM	031162100
BBIO	BRIDGEBIO PHARMA INC	245,346	$18.27M	2.4%	—	—	COM	10806X102
SKYE	SKYE BIOSCIENCE INC	678,928	$471K	0.1%	—	—	COM NEW	83086J200
ORGO	ORGANOGENESIS HLDGS INC	550,000	$1.337M	0.2%	—	—	COM	68621F102
TLT	ISHARES TR	47,000	$4.062M	0.5%	—	—	CALL	464287432
APRE	APREA THERAPEUTICS INC	270,000	$217K	0.0%	—	—	COM NEW	03836J201