GOSSAMER BIO INC

Institution	Shares	Value ($000)
Monashee Investment Management LLC	1,000,000	$3,100
Integral Health Asset Management, LLC	1,000,000	$3,100
Hennion & Walsh Asset Management, Inc.	652,977	$2,024
Virtus Investment Advisers, LLC	73,896	$229
SHERBROOKE PARK ADVISERS LLC	13,347	$41
Vickerman Investment Advisors, Inc.	34,787	$108
PROFUND ADVISORS LLC	116,503	$361
China Universal Asset Management Co., Ltd.	47,716	$148
Lighthouse Investment Partners, LLC	92,500	$287
Eaton Financial Holdings Company, LLC	14,199	$44
MMA ASSET MANAGEMENT LLC	10,000	$31
Rafferty Asset Management, LLC	312,804	$970
Caprock Group, LLC	80,000	$248
MANGROVE PARTNERS IM, LLC	30,747	$95
ALGERT GLOBAL LLC	332,336	$1
Squarepoint Ops LLC	221,591	$687
Caption Management, LLC	75,375	$234
HRT FINANCIAL LP	956,879	$3
Engineers Gate Manager LP	51,129	$159
AlphaCore Capital LLC	26,377	$82

Increased Positions (65)

MB Generational Wealth, LLC

Value ($000) $4,977 (+33.8%) Shares 1,605,449 (+13.5%)

Samsara BioCapital, LLC

Value ($000) $22,390 (+38.9%) Shares 7,222,559 (+17.8%)

EntryPoint Capital, LLC

Value ($000) $326 (+141.6%) Shares 105,085 (+105.0%)

683 Capital Management, LLC

Value ($000) $16,091 (+20.9%) Shares 5,190,800 (+2.6%)

Corient Private Wealth LLC

Value ($000) $11,922 (+22559.0%) Shares 3,845,885 (+19123.7%)

XTX Topco Ltd

Value ($000) $1,415 (+95.7%) Shares 456,329 (+66.1%)

Atom Investors LP

Value ($000) $637 (+82.9%) Shares 205,639 (+55.1%)

JACOBS LEVY EQUITY MANAGEMENT, INC

Value ($000) $6,752 (+82.3%) Shares 2,178,033 (+54.7%)

TWO SIGMA INVESTMENTS, LP

Value ($000) $10,531 (+75.1%) Shares 3,397,110 (+48.5%)

AXQ CAPITAL, LP

Value ($000) $196 (+60.5%) Shares 63,117 (+36.1%)

Walleye Capital LLC

Value ($000) $3,339 (+132.6%) Shares 1,077,032 (+97.4%)

TWO SIGMA ADVISERS, LP

Value ($000) $8,050 (+63.7%) Shares 2,596,900 (+38.9%)

STATE STREET CORP

Value ($000) $28,864 (+182.6%) Shares 9,310,969 (+139.7%)

Connor, Clark & Lunn Investment Management Ltd.

Value ($000) $1,637 (+2345.7%) Shares 528,053 (+1974.9%)

BALYASNY ASSET MANAGEMENT L.P.

Value ($000) $4,702 (+132.0%) Shares 1,516,691 (+96.8%)

BlackRock, Inc.

Value ($000) $52,876 (+45.2%) Shares 17,056,878 (+23.2%)

GOLDMAN SACHS GROUP INC

Value ($000) $5,556 (+605.1%) Shares 1,792,114 (+498.2%)

Susquehanna Portfolio Strategies, LLC

Value ($000) $345 (+594.4%) Shares 111,350 (+489.2%)

VANGUARD GROUP INC

Value ($000) $39,907 (+26.3%) Shares 12,873,209 (+7.2%)

AQR CAPITAL MANAGEMENT LLC

Value ($000) $3,470 (+104.0%) Shares 1,119,240 (+73.1%)

Institution	Prev Shares	Curr Shares	Change
MB Generational Wealth, LLC	1,414,824	1,605,449	+190,625 (+13.5%)
Samsara BioCapital, LLC	6,130,268	7,222,559	+1,092,291 (+17.8%)
EntryPoint Capital, LLC	51,264	105,085	+53,821 (+105.0%)
683 Capital Management, LLC	5,059,200	5,190,800	+131,600 (+2.6%)
Corient Private Wealth LLC	20,006	3,845,885	+3,825,879 (+19123.7%)
XTX Topco Ltd	274,782	456,329	+181,547 (+66.1%)
Atom Investors LP	132,552	205,639	+73,087 (+55.1%)
JACOBS LEVY EQUITY MANAGEMENT, INC	1,408,118	2,178,033	+769,915 (+54.7%)
TWO SIGMA INVESTMENTS, LP	2,287,251	3,397,110	+1,109,859 (+48.5%)
AXQ CAPITAL, LP	46,367	63,117	+16,750 (+36.1%)
Walleye Capital LLC	545,679	1,077,032	+531,353 (+97.4%)
TWO SIGMA ADVISERS, LP	1,870,100	2,596,900	+726,800 (+38.9%)
STATE STREET CORP	3,883,667	9,310,969	+5,427,302 (+139.7%)
Connor, Clark & Lunn Investment Management Ltd.	25,449	528,053	+502,604 (+1974.9%)
BALYASNY ASSET MANAGEMENT L.P.	770,574	1,516,691	+746,117 (+96.8%)
BlackRock, Inc.	13,846,054	17,056,878	+3,210,824 (+23.2%)
GOLDMAN SACHS GROUP INC	299,582	1,792,114	+1,492,532 (+498.2%)
Susquehanna Portfolio Strategies, LLC	18,900	111,350	+92,450 (+489.2%)
VANGUARD GROUP INC	12,009,773	12,873,209	+863,436 (+7.2%)
AQR CAPITAL MANAGEMENT LLC	646,615	1,119,240	+472,625 (+73.1%)

Decreased Positions (42)

Octagon Capital Advisors LP

Value ($000) $43,138 (-3.8%) Shares 13,915,371 (-18.4%)

Palo Alto Investors LP

Value ($000) $13,862 (-3.5%) Shares 4,471,592 (-18.2%)

SILVERARC CAPITAL MANAGEMENT, LLC

Value ($000) $6,621 (-47.3%) Shares 2,135,722 (-55.3%)

Monaco Asset Management SAM

Value ($000) $959 (-73.6%) Shares 309,211 (-77.6%)

PLATINUM INVESTMENT MANAGEMENT LTD

Value ($000) $1,742 (-13.3%) Shares 561,951 (-26.5%)

PERCEPTIVE ADVISORS LLC

Value ($000) $9,733 (-2.9%) Shares 3,139,669 (-17.7%)

RENAISSANCE TECHNOLOGIES LLC

Value ($000) $2,043 (-73.9%) Shares 658,888 (-77.9%)

Jain Global LLC

Value ($000) $862 (-68.9%) Shares 278,189 (-73.6%)

Alyeska Investment Group, L.P.

Value ($000) $2,818 (-43.9%) Shares 909,087 (-52.4%)

BRIDGEWAY CAPITAL MANAGEMENT, LLC

Value ($000) $546 (-38.2%) Shares 176,000 (-47.6%)

GSA CAPITAL PARTNERS LLP

Value ($000) $0 (-67.9%) Shares 51,860 (-72.8%)

CITADEL ADVISORS LLC

Value ($000) $2,185 (-63.6%) Shares 704,787 (-69.1%)

Russell Investments Group, Ltd.

Value ($000) $530 (-70.6%) Shares 171,071 (-75.0%)

UBS Group AG

Value ($000) $5,491 (-24.6%) Shares 1,771,381 (-36.1%)

ROYAL BANK OF CANADA

Value ($000) $17 (-99.4%) Shares 5,494 (-99.5%)

Nuveen, LLC

Value ($000) $956 (-66.2%) Shares 308,522 (-71.4%)

BANK OF AMERICA CORP /DE/

Value ($000) $5,911 (-22.0%) Shares 1,906,669 (-33.8%)

JANE STREET GROUP, LLC

Value ($000) $482 (-73.9%) Shares 155,591 (-77.8%)

Graham Capital Management, L.P.

Value ($000) $113 (-36.2%) Shares 36,467 (-45.9%)

NORTHERN TRUST CORP

Value ($000) $4,391 (+11.7%) Shares 1,416,540 (-5.3%)

Institution	Prev Shares	Curr Shares	Change
Octagon Capital Advisors LP	17,050,000	13,915,371	-3,134,629 (-18.4%)
Palo Alto Investors LP	5,464,349	4,471,592	-992,757 (-18.2%)
SILVERARC CAPITAL MANAGEMENT, LLC	4,779,082	2,135,722	-2,643,360 (-55.3%)
Monaco Asset Management SAM	1,379,416	309,211	-1,070,205 (-77.6%)
PLATINUM INVESTMENT MANAGEMENT LTD	764,165	561,951	-202,214 (-26.5%)
PERCEPTIVE ADVISORS LLC	3,812,797	3,139,669	-673,128 (-17.7%)
RENAISSANCE TECHNOLOGIES LLC	2,980,188	658,888	-2,321,300 (-77.9%)
Jain Global LLC	1,054,356	278,189	-776,167 (-73.6%)
Alyeska Investment Group, L.P.	1,909,087	909,087	-1,000,000 (-52.4%)
BRIDGEWAY CAPITAL MANAGEMENT, LLC	335,900	176,000	-159,900 (-47.6%)
GSA CAPITAL PARTNERS LLP	190,815	51,860	-138,955 (-72.8%)
CITADEL ADVISORS LLC	2,284,216	704,787	-1,579,429 (-69.1%)
Russell Investments Group, Ltd.	685,049	171,071	-513,978 (-75.0%)
UBS Group AG	2,770,046	1,771,381	-998,665 (-36.1%)
ROYAL BANK OF CANADA	1,001,606	5,494	-996,112 (-99.5%)
Nuveen, LLC	1,077,135	308,522	-768,613 (-71.4%)
BANK OF AMERICA CORP /DE/	2,881,904	1,906,669	-975,235 (-33.8%)
JANE STREET GROUP, LLC	702,065	155,591	-546,474 (-77.8%)
Graham Capital Management, L.P.	67,367	36,467	-30,900 (-45.9%)
NORTHERN TRUST CORP	1,495,403	1,416,540	-78,863 (-5.3%)

Exited Positions (14)

Eversept Partners, LP

Value ($000) $2,433 Shares 925,233

TANG CAPITAL MANAGEMENT LLC

Value ($000) $2,104 Shares 800,000

Focus Partners Wealth

Value ($000) $3,485 Shares 1,325,198

Woodline Partners LP

Value ($000) $1,302 Shares 495,153

ADAGE CAPITAL PARTNERS GP, L.L.C.

Value ($000) $1,911 Shares 726,800

DLD Asset Management, LP

Value ($000) $99 Shares 37,543

Quadrature Capital Ltd

Value ($000) $209 Shares 79,709

ALPS ADVISORS INC

Value ($000) $261 Shares 99,155

OMERS ADMINISTRATION Corp

Value ($000) $155 Shares 59,100

GROUP ONE TRADING, L.P.

Value ($000) $196 Shares 74,531

BANK OF NOVA SCOTIA

Value ($000) $92 Shares 35,000

BRIGHTON JONES LLC

Value ($000) $36 Shares 13,754

HSBC HOLDINGS PLC

Value ($000) $68 Shares 25,969

GTS SECURITIES LLC

Value ($000) $28 Shares 10,627

Institution	Prev Shares	Prev Value ($000)
Eversept Partners, LP	925,233	$2,433
TANG CAPITAL MANAGEMENT LLC	800,000	$2,104
Focus Partners Wealth	1,325,198	$3,485
Woodline Partners LP	495,153	$1,302
ADAGE CAPITAL PARTNERS GP, L.L.C.	726,800	$1,911
DLD Asset Management, LP	37,543	$99
Quadrature Capital Ltd	79,709	$209
ALPS ADVISORS INC	99,155	$261
OMERS ADMINISTRATION Corp	59,100	$155
GROUP ONE TRADING, L.P.	74,531	$196
BANK OF NOVA SCOTIA	35,000	$92
BRIGHTON JONES LLC	13,754	$36
HSBC HOLDINGS PLC	25,969	$68
GTS SECURITIES LLC	10,627	$28