Location: San Francisco, CA
CIK: 0000909661 · Show all filings
Period: Q4 2025 (← Previous) (Next →)
Filing Date: Aug 14, 2026
Total Value: $23.1B
| Ticker | Issuer | Shares | Value | % | Share Price | Est. Cost/Share | Unrealized @ Report Date | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|---|
| SPY | SPDR S&P 500 ETF TR | 3,000,000 | $2.046B | 8.9% | $681.92 | — | — | PUT | 78462F103 |
| RVMD | REVOLUTION MEDICINES INC | 14,582,796 | $1.162B | 5.0% | $79.65 | — | — | COM | 76155X100 |
| MSFT | MICROSOFT CORP | 2,214,079 | $1.071B | 4.6% | $483.62 | — | — | COM | 594918104 |
| AMZN | AMAZON COM INC | 4,499,894 | $1.039B | 4.5% | $230.82 | — | — | COM | 023135106 |
| EA | ELECTRONIC ARTS INC | 5,035,000 | $1.029B | 4.5% | $204.33 | — | — | COM | 285512109 |
| AON | AON PLC | 2,665,238 | $941M | 4.1% | $352.88 | — | — | SHS CL A | G0403H108 |
| NTRA | NATERA INC | 3,914,366 | $897M | 3.9% | $229.09 | — | — | COM | 632307104 |
| BSX | BOSTON SCIENTIFIC CORP | 7,439,564 | $709M | 3.1% | $95.35 | — | — | COM | 101137107 |
| RSP | INVESCO EXCHANGE TRADED FD T | 3,600,000 | $690M | 3.0% | $191.56 | — | — | PUT | 46137V357 |
| EXEL | EXELIXIS INC | 15,709,500 | $689M | 3.0% | $43.83 | — | — | COM | 30161Q104 |
| BBIO | BRIDGEBIO PHARMA INC | 8,998,463 | $688M | 3.0% | $76.49 | — | — | COM | 10806X102 |
| EXAS | EXACT SCIENCES CORP | 6,405,000 | $650M | 2.8% | $101.56 | — | — | COM | 30063P105 |
| HYG | ISHARES TR | 8,000,000 | $645M | 2.8% | $80.63 | — | — | PUT | 464288513 |
| PTGX | PROTAGONIST THERAPEUTICS INC | 6,144,006 | $537M | 2.3% | $87.34 | — | — | COM | 74366E102 |
| WAB | WABTEC | 2,476,003 | $529M | 2.3% | $213.45 | — | — | COM | 929740108 |
| UNH | UNITEDHEALTH GROUP INC | 1,598,906 | $528M | 2.3% | $330.11 | — | — | COM | 91324P102 |
| — | CYBERARK SOFTWARE LTD | 1,053,040 | $470M | 2.0% | $446.06 | — | — | SHS | M2682V108 |
| DIS | DISNEY WALT CO | 4,125,991 | $469M | 2.0% | $113.77 | — | — | COM | 254687106 |
| SNPS | SYNOPSYS INC | 999,200 | $469M | 2.0% | $469.72 | — | — | COM | 871607107 |
| LLY | ELI LILLY & CO | 375,000 | $403M | 1.7% | $1074.68 | — | — | PUT | 532457108 |
| TMO | THERMO FISHER SCIENTIFIC INC | 635,685 | $368M | 1.6% | $579.45 | — | — | COM | 883556102 |
| LNTH | LANTHEUS HLDGS INC | 5,427,479 | $361M | 1.6% | $66.55 | — | — | COM | 516544103 |
| ARMK | ARAMARK | 9,357,046 | $345M | 1.5% | $36.86 | — | — | COM | 03852U106 |
| CRM | SALESFORCE INC | 1,261,177 | $334M | 1.4% | $264.91 | — | — | COM | 79466L302 |
| SCHW | SCHWAB CHARLES CORP | 3,339,657 | $334M | 1.4% | $99.91 | — | — | COM | 808513105 |
| CRNX | CRINETICS PHARMACEUTICALS IN | 6,933,098 | $323M | 1.4% | $46.55 | — | — | COM | 22663K107 |
| AVGO | BROADCOM INC | 892,400 | $309M | 1.3% | $346.10 | — | — | COM | 11135F101 |
| LQDA | LIQUIDIA CORPORATION | 8,656,038 | $299M | 1.3% | $34.49 | — | — | COM NEW | 53635D202 |
| NDAQ | NASDAQ INC | 2,989,213 | $290M | 1.3% | $97.13 | — | — | COM | 631103108 |
| BEAM | BEAM THERAPEUTICS INC | 10,063,111 | $279M | 1.2% | $27.72 | — | — | COM | 07373V105 |
| KKR | KKR & CO INC | 2,017,700 | $257M | 1.1% | $127.48 | — | — | COM | 48251W104 |
| GOOG | ALPHABET INC | 787,040 | $247M | 1.1% | $313.80 | — | — | CAP STK CL C | 02079K107 |
| MCK | MCKESSON CORP | 298,900 | $245M | 1.1% | $820.29 | — | — | COM | 58155Q103 |
| V | VISA INC | 695,910 | $244M | 1.1% | $350.71 | — | — | COM CL A | 92826C839 |
| RNAM | AVIDITY BIOSCIENCES INC | 3,233,000 | $233M | 1.0% | $72.13 | — | — | COM | 05370A108 |
| NYT | NEW YORK TIMES CO | 3,280,678 | $228M | 1.0% | $69.42 | — | — | CL A | 650111107 |
| — | DAYFORCE INC | 2,925,000 | $202M | 0.9% | $69.16 | — | — | COM | 15677J108 |
| GRAL | GRAIL INC | 2,342,684 | $201M | 0.9% | $85.59 | — | — | COM | 384747101 |
| BITW | BITWISE 10 CRYPTO INDEX ETF | 3,385,500 | $199M | 0.9% | $58.76 | — | — | UNIT BENEFICIAL | 091749101 |
| CBRE | CBRE GROUP INC | 983,771 | $158M | 0.7% | $160.79 | — | — | CL A | 12504L109 |
| AGIO | AGIOS PHARMACEUTICALS INC | 5,159,505 | $140M | 0.6% | $27.22 | — | — | COM | 00847X104 |
| CNTA | CENTESSA PHARMACEUTICALS PLC | 5,377,068 | $134M | 0.6% | $25.01 | — | — | SPONSORED ADS | 152309100 |
| BBNX | BETA BIONICS INC | 4,313,920 | $131M | 0.6% | $30.47 | — | — | COM | 08659B102 |
| CAH | CARDINAL HEALTH INC | 576,000 | $118M | 0.5% | $205.50 | — | — | COM | 14149Y108 |
| TNGX | TANGO THERAPEUTICS INC | 13,061,411 | $116M | 0.5% | $8.86 | — | — | COM | 87583X109 |
| HIMS | HIMS & HERS HEALTH INC | 3,386,986 | $110M | 0.5% | $32.47 | — | — | COM CL A | 433000106 |
| IBIT | ISHARES BITCOIN TRUST ETF | 2,137,100 | $106M | 0.5% | $49.65 | — | — | SHS BEN INT | 46438F101 |
| MA | MASTERCARD INCORPORATED | 172,671 | $98.57M | 0.4% | $570.88 | — | — | CL A | 57636Q104 |
| — | CIDARA THERAPEUTICS INC | 382,800 | $84.56M | 0.4% | $220.89 | — | — | COM NEW | 171757206 |
| THC | TENET HEALTHCARE CORP | 372,153 | $73.95M | 0.3% | $198.72 | — | — | COM NEW | 88033G407 |
| WELL | WELLTOWER INC | 343,000 | $63.66M | 0.3% | $185.61 | — | — | COM | 95040Q104 |
| TRU | TRANSUNION | 675,000 | $57.88M | 0.3% | $85.75 | — | — | COM | 89400J107 |
| TYRA | TYRA BIOSCIENCES INC | 2,066,818 | $54.34M | 0.2% | $26.29 | — | — | COM | 90240B106 |
| VNET | VNET GROUP INC | 6,285,386 | $53.17M | 0.2% | $8.46 | — | — | SPONSORED ADS A | 90138A103 |
| ABVX | ABIVAX SA | 387,000 | $52.19M | 0.2% | $134.85 | — | — | SPONSORED ADS | 00370M103 |
| ENTA | ENANTA PHARMACEUTICALS INC | 2,772,262 | $43.72M | 0.2% | $15.77 | — | — | COM | 29251M106 |
| INSM | INSMED INC | 250,000 | $43.51M | 0.2% | $174.04 | — | — | CALL | 457669307 |
| ASMB | ASSEMBLY BIOSCIENCES INC | 1,227,590 | $41.75M | 0.2% | $34.01 | — | — | COM NEW | 045396207 |
| BIDU | BAIDU INC | 315,300 | $41.2M | 0.2% | $130.66 | — | — | SPON ADR REP A | 056752108 |
| ALNY | ALNYLAM PHARMACEUTICALS INC | 100,000 | $39.77M | 0.2% | $397.65 | — | — | PUT | 02043Q107 |
| JOYY | JOYY INC | 578,200 | $37.44M | 0.2% | $64.76 | — | — | ADS REPSTG COM A | 46591M109 |
| ETHA | ISHARES ETHEREUM TR | 1,481,001 | $33.22M | 0.1% | $22.43 | — | — | SHS | 46438R105 |
| GPCR | STRUCTURE THERAPEUTICS INC | 454,000 | $31.58M | 0.1% | $69.55 | — | — | SPONSORED ADS | 86366E106 |
| MLYS | MINERALYS THERAPEUTICS INC | 823,296 | $29.88M | 0.1% | $36.29 | — | — | COM | 603170101 |
| SUNC | SUNOCOCORP LLC | 606,277 | $29.88M | 0.1% | $49.28 | — | — | COM SHS LLC | 86765Q106 |
| PCSC | PERCEPTIVE CAP SOLUTIONS COR | 2,250,000 | $29.32M | 0.1% | $13.03 | — | — | CL A ORD SHS | G70077105 |
| TERN | TERNS PHARMACEUTICALS INC | 642,000 | $25.94M | 0.1% | $40.40 | — | — | COM | 880881107 |
| EHC | ENCOMPASS HEALTH CORP | 234,500 | $24.89M | 0.1% | $106.14 | — | — | COM | 29261A100 |
| AMKR | AMKOR TECHNOLOGY INC | 464,000 | $18.32M | 0.1% | $39.48 | — | — | COM | 031652100 |
| VSTM | VERASTEM INC | 2,000,000 | $15.44M | 0.1% | $7.72 | — | — | COM NEW | 92337C203 |
| DOCS | DOXIMITY INC | 311,000 | $13.77M | 0.1% | $44.28 | — | — | CL A | 26622P107 |
| GH | GUARDANT HEALTH INC | 109,000 | $11.13M | 0.0% | $102.14 | — | — | COM | 40131M109 |
| MDLN | MEDLINE INC | 260,000 | $10.92M | 0.0% | $42.00 | — | — | COM CL A | 58507V107 |
| EDU | NEW ORIENTAL ED & TECHNOLOGY | 196,000 | $10.79M | 0.0% | $55.03 | — | — | SPON ADR | 647581206 |
| NERV | MINERVA NEUROSCIENCES INC | 2,365,000 | $9.507M | 0.0% | $4.02 | — | — | COM NEW | 603380205 |
| WGS | GENEDX HOLDINGS CORP | 70,000 | $9.104M | 0.0% | $130.06 | — | — | COM CL A | 81663L200 |
| ETH | GRAYSCALE ETHEREUM MINI TR E | 228,340 | $6.407M | 0.0% | $28.06 | — | — | SHS NEW | 38964R203 |
| PRME | PRIME MEDICINE INC | 1,240,843 | $4.306M | 0.0% | $3.47 | — | — | COM | 74168J101 |
| OSCR | OSCAR HEALTH INC | 264,000 | $3.794M | 0.0% | $14.37 | — | — | CL A | 687793109 |
| MDGL | MADRIGAL PHARMACEUTICALS INC | 3,319 | $1.933M | 0.0% | $582.34 | — | — | COM | 558868105 |
| SMC | SUMMIT MIDSTREAM CORPORATION | 58,214 | $1.553M | 0.0% | $26.68 | — | — | COM | 86614G101 |
| NVAX | NOVAVAX INC | 195,000 | $1.31M | 0.0% | $6.72 | — | — | COM NEW | 670002401 |
| SDGR | SCHRODINGER INC | 71,000 | $1.269M | 0.0% | $17.88 | — | — | COM | 80810D103 |
| TEVA | TEVA PHARMACEUTICAL INDS LTD | 40,000 | $1.248M | 0.0% | $31.21 | — | — | SPONSORED ADS | 881624209 |
| CAPR | CAPRICOR THERAPEUTICS INC | 41,000 | $1.183M | 0.0% | $28.86 | — | — | COM NEW | 14070B309 |
| ARWR | ARROWHEAD PHARMACEUTICALS IN | 15,800 | $1.049M | 0.0% | $66.39 | — | — | COM | 04280A100 |
| ALVO | ALVOTECH | 199,675 | $1.024M | 0.0% | $5.13 | — | — | ORDINARY SHARES | L01800108 |
| BTSG | BRIGHTSPRING HEALTH SVCS INC | 22,000 | $824K | 0.0% | $37.45 | — | — | COM | 10950A106 |
| ROIV | ROIVANT SCIENCES LTD | 37,000 | $803K | 0.0% | $21.70 | — | — | SHS | G76279101 |
| ARQT | ARCUTIS BIOTHERAPEUTICS INC | 26,000 | $755K | 0.0% | $29.04 | — | — | COM | 03969K108 |
| AXSM | AXSOME THERAPEUTICS INC | 4,000 | $731K | 0.0% | $182.64 | — | — | COM | 05464T104 |
| COGT | COGENT BIOSCIENCES INC | 17,000 | $604K | 0.0% | $35.52 | — | — | COM | 19240Q201 |
| ALKS | ALKERMES PLC | 20,800 | $582K | 0.0% | $27.98 | — | — | SHS | G01767105 |
| INSM | INSMED INC | 3,000 | $522K | 0.0% | $174.04 | — | — | COM PAR $.01 | 457669307 |
| KRYS | KRYSTAL BIOTECH INC | 2,000 | $493K | 0.0% | $246.54 | — | — | COM | 501147102 |
| PGNY | PROGYNY INC | 18,000 | $462K | 0.0% | $25.68 | — | — | COM | 74340E103 |
| TVTX | TRAVERE THERAPEUTICS INC | 12,000 | $459K | 0.0% | $38.21 | — | — | COM | 89422G107 |
| HQY | HEALTHEQUITY INC | 5,000 | $458K | 0.0% | $91.61 | — | — | COM | 42226A107 |
| CELC | CELCUITY INC | 4,000 | $399K | 0.0% | $99.74 | — | — | COM | 15102K100 |
| OMER | OMEROS CORP | 23,000 | $395K | 0.0% | $17.18 | — | — | COM | 682143102 |
| IONS | IONIS PHARMACEUTICALS INC | 4,800 | $380K | 0.0% | $79.11 | — | — | COM | 462222100 |
| LIVN | LIVANOVA PLC | 6,000 | $369K | 0.0% | $61.53 | — | — | SHS | G5509L101 |
| GMED | GLOBUS MED INC | 4,000 | $349K | 0.0% | $87.31 | — | — | CL A | 379577208 |
| COR | CENCORA INC | 1,000 | $338K | 0.0% | $337.75 | — | — | COM | 03073E105 |
| QURE | UNIQURE NV | 14,000 | $335K | 0.0% | $23.93 | — | — | SHS | N90064101 |
| ONC | BEONE MEDICINES LTD | 1,100 | $334K | 0.0% | $303.81 | — | — | SPONSORED ADS | 07725L102 |
| CGON | CG ONCOLOGY INC | 8,000 | $332K | 0.0% | $41.52 | — | — | COM | 156944100 |
| SRRK | SCHOLAR ROCK HLDG CORP | 7,000 | $308K | 0.0% | $44.05 | — | — | COM | 80706P103 |
| IMVT | IMMUNOVANT INC | 12,000 | $305K | 0.0% | $25.42 | — | — | COM | 45258J102 |
| NUVL | NUVALENT INC | 3,000 | $302K | 0.0% | $100.59 | — | — | COM | 670703107 |
| ASND | ASCENDIS PHARMA A/S | 1,400 | $299K | 0.0% | $213.24 | — | — | SPONSORED ADR | 04351P101 |
| VCYT | VERACYTE INC | 7,000 | $295K | 0.0% | $42.10 | — | — | COM | 92337F107 |
| GKOS | GLAUKOS CORP | 2,600 | $294K | 0.0% | $112.91 | — | — | COM | 377322102 |
| SLDPW | SOLID POWER INC | 405,316 | $287K | 0.0% | $0.71 | — | — | *W EXP 12/08/202 | 83422N113 |
| STOK | STOKE THERAPEUTICS INC | 9,000 | $286K | 0.0% | $31.74 | — | — | COM | 86150R107 |
| SBRA | SABRA HEALTH CARE REIT INC | 14,000 | $265K | 0.0% | $18.94 | — | — | COM | 78573L106 |
| MMSI | MERIT MED SYS INC | 3,000 | $264K | 0.0% | $88.14 | — | — | COM | 589889104 |
| GRFS | GRIFOLS S A | 28,000 | $262K | 0.0% | $9.35 | — | — | SP ADR REP B NVT | 398438408 |
| ACLX | ARCELLX INC | 4,000 | $261K | 0.0% | $65.20 | — | — | COMMON STOCK | 03940C100 |
| NUVB | NUVATION BIO INC | 29,000 | $260K | 0.0% | $8.96 | — | — | COM CL A | 67080N101 |
| URGN | UROGEN PHARMA LTD | 11,000 | $258K | 0.0% | $23.42 | — | — | COM | M96088105 |
| PACB | PACIFIC BIOSCIENCES CALIF IN | 135,000 | $252K | 0.0% | $1.87 | — | — | COM | 69404D108 |
| GEHC | GE HEALTHCARE TECHNOLOGIES I | 3,000 | $246K | 0.0% | $82.02 | — | — | COMMON STOCK | 36266G107 |
| TWST | TWIST BIOSCIENCE CORP | 7,650 | $243K | 0.0% | $31.72 | — | — | COM | 90184D100 |
| MIRM | MIRUM PHARMACEUTICALS INC | 3,000 | $237K | 0.0% | $78.99 | — | — | COM | 604749101 |
| SLNO | SOLENO THERAPEUTICS INC | 5,000 | $232K | 0.0% | $46.30 | — | — | COM | 834203309 |
| PCVX | VAXCYTE INC | 5,000 | $231K | 0.0% | $46.14 | — | — | COM | 92243G108 |
| FOLD | AMICUS THERAPEUTICS INC | 16,000 | $228K | 0.0% | $14.24 | — | — | COM | 03152W109 |
| ANNA | ALEANNA INC | 78,400 | $223K | 0.0% | $2.85 | — | — | COM CL A | 01444V103 |
| NEO | NEOGENOMICS INC | 19,000 | $223K | 0.0% | $11.76 | — | — | COM NEW | 64049M209 |
| ICLR | ICON PLC | 1,200 | $219K | 0.0% | $182.22 | — | — | SHS | G4705A100 |
| ESTA | ESTABLISHMENT LABS HLDGS INC | 3,000 | $219K | 0.0% | $72.88 | — | — | COM | G31249108 |
| OCUL | OCULAR THERAPEUTIX INC | 18,000 | $219K | 0.0% | $12.14 | — | — | COM | 67576A100 |
| SNDX | SYNDAX PHARMACEUTICALS INC | 10,000 | $210K | 0.0% | $21.01 | — | — | COM | 87164F105 |
| PGEN | PRECIGEN INC | 50,000 | $209K | 0.0% | $4.18 | — | — | COM | 74017N105 |
| HR | HEALTHCARE RLTY TR | 12,000 | $203K | 0.0% | $16.95 | — | — | CL A COM | 42226K105 |
| DYN | DYNE THERAPEUTICS INC | 10,000 | $196K | 0.0% | $19.56 | — | — | COM | 26818M108 |
| BCRX | BIOCRYST PHARMACEUTICALS INC | 24,000 | $187K | 0.0% | $7.80 | — | — | COM | 09058V103 |
| TVRD | TVARDI THERAPEUTICS INC | 43,225 | $186K | 0.0% | $4.30 | — | — | COM | 140755307 |
| ADPT | ADAPTIVE BIOTECHNOLOGIES COR | 11,000 | $179K | 0.0% | $16.24 | — | — | COM | 00650F109 |
| ANNAW | ALEANNA INC | 990,000 | $163K | 0.0% | $0.17 | — | — | *W EXP 12/13/202 | 01444V111 |
| ARDX | ARDELYX INC | 23,000 | $134K | 0.0% | $5.83 | — | — | COM | 039697107 |
| BGLWW | BLUE GOLD LTD | 300,000 | $132K | 0.0% | $0.44 | — | — | *W EXP 04/01/203 | G1331C112 |
| RVMDW | REVOLUTION MEDICINES INC | 120,085 | $113K | 0.0% | $0.94 | — | — | *W EXP 12/17/202 | 76155X118 |
| RANI | RANI THERAPEUTICS HLDGS INC | 78,000 | $105K | 0.0% | $1.35 | — | — | COM CL A | 753018100 |
| ALT | ALTIMMUNE INC | 27,600 | $99,636 | 0.0% | $3.61 | — | — | COM NEW | 02155H200 |
| IOVA | IOVANCE BIOTHERAPEUTICS INC | 26,000 | $70,980 | 0.0% | $2.73 | — | — | COM | 462260100 |
| GERN | GERON CORP | 43,000 | $56,760 | 0.0% | $1.32 | — | — | COM | 374163103 |
| EVH | EVOLENT HEALTH INC | 14,000 | $56,000 | 0.0% | $4.00 | — | — | CL A | 30050B101 |
| CCCC | C4 THERAPEUTICS INC | 28,000 | $53,480 | 0.0% | $1.91 | — | — | COM STK | 12529R107 |
| IRWD | IRONWOOD PHARMACEUTICALS INC | 13,000 | $43,810 | 0.0% | $3.37 | — | — | COM CL A | 46333X108 |
| CGC | CANOPY GROWTH CORP | 30,000 | $34,200 | 0.0% | $1.14 | — | — | COM NEW | 138035704 |
| NVNIW | NVNI GROUP LIMITED | 375,000 | $22,500 | 0.0% | $0.06 | — | — | *W EXP 11/01/202 | G50716110 |
| BYND | BEYOND MEAT INC | 19,000 | $15,580 | 0.0% | $0.82 | — | — | COM | 08862E109 |