ORBIMED ADVISORS LLC Diversified Active

Location: New York, NY

CIK: 0001055951 · Show all filings

Period: Q1 2016 (← Previous) (Next →)

Filing Date: May 16, 2016

Total Value: $9.504B (99.4% shares, 0.6% debt)

Holdings (141)

BMY BRISTOL MYERS SQUIBB CO 5.1%
Value $487M Shares 7,624,900 Est. Cost Unrealized
HCA HCA HOLDINGS INC 4.7%
Value $448M Shares 5,737,100 Est. Cost Unrealized
AMGN AMGEN INC 4.5%
Value $431M Shares 2,876,000 Est. Cost Unrealized
BSX BOSTON SCIENTIFIC CORP 4.4%
Value $423M Shares 22,479,700 Est. Cost Unrealized
ABBV ABBVIE INC 4.4%
Value $422M Shares 7,395,700 Est. Cost Unrealized
ALLERGAN PLC 4.4%
Value $422M Shares 1,572,715 Est. Cost Unrealized
BIIB BIOGEN INC 4.2%
Value $397M Shares 1,526,300 Est. Cost Unrealized
CELGENE CORP 4.0%
Value $378M Shares 3,774,077 Est. Cost Unrealized
GILD GILEAD SCIENCES INC 2.9%
Value $277M Shares 3,019,200 Est. Cost Unrealized
ALEXION PHARMACEUTICALS INC 2.7%
Value $260M Shares 1,870,600 Est. Cost Unrealized
IMPAX LABORATORIES INC 2.3%
Value $217M Shares 6,776,100 Est. Cost Unrealized
TMO THERMO FISHER SCIENTIFIC INC 2.1%
Value $203M Shares 1,435,000 Est. Cost Unrealized
INCY INCYTE CORP 2.1%
Value $200M Shares 2,755,078 Est. Cost Unrealized
REGN REGENERON PHARMACEUTICALS 2.0%
Value $192M Shares 533,000 Est. Cost Unrealized
LLY LILLY ELI & CO 1.9%
Value $183M Shares 2,541,300 Est. Cost Unrealized
WELLCARE HEALTH PLANS INC 1.9%
Value $177M Shares 1,903,300 Est. Cost Unrealized
ISRG INTUITIVE SURGICAL INC 1.8%
Value $166M Shares 276,800 Est. Cost Unrealized
EXPRESS SCRIPTS HLDG CO 1.7%
Value $166M Shares 2,421,000 Est. Cost Unrealized
VRTX VERTEX PHARMACEUTICALS INC 1.6%
Value $149M Shares 1,869,400 Est. Cost Unrealized
ILMN ILLUMINA INC 1.5%
Value $146M Shares 900,000 Est. Cost Unrealized
TEVA TEVA PHARMACEUTICAL INDS LTD 1.5%
Value $144M Shares 2,696,000 Est. Cost Unrealized
INTERCEPT PHARMACEUTICALS IN 1.5%
Value $144M Shares 1,120,000 Est. Cost Unrealized
A AGILENT TECHNOLOGIES INC 1.5%
Value $139M Shares 3,495,000 Est. Cost Unrealized
WRIGHT MED GROUP N V 1.5%
Value $139M Shares 8,345,110 Est. Cost Unrealized
MAGELLAN HEALTH INC 1.4%
Value $130M Shares 1,909,000 Est. Cost Unrealized
IRWD IRONWOOD PHARMACEUTICALS INC 1.3%
Value $126M Shares 11,550,400 Est. Cost Unrealized
COOPER COS INC 1.3%
Value $123M Shares 795,900 Est. Cost Unrealized
PFE PFIZER INC 1.3%
Value $122M Shares 4,122,000 Est. Cost Unrealized
NBIX NEUROCRINE BIOSCIENCES INC 1.1%
Value $105M Shares 2,653,874 Est. Cost Unrealized
UNH UNITEDHEALTH GROUP INC 1.1%
Value $105M Shares 812,000 Est. Cost Unrealized
RELYPSA INC 1.1%
Value $100M Shares 7,400,000 Est. Cost Unrealized
AGN 5.5 03/01/18 A ALLERGAN PLC 1.0%
Value $95.77M Shares 104,200 Est. Cost Unrealized
ACHILLION PHARMACEUTICALS IN 0.9%
Value $88.93M Shares 11,519,700 Est. Cost Unrealized
OPHTHOTECH CORP 0.9%
Value $88.53M Shares 2,094,500 Est. Cost Unrealized
BMRN BIOMARIN PHARMACEUTICAL INC 0.9%
Value $84.39M Shares 1,023,200 Est. Cost Unrealized
TESARO INC 0.9%
Value $84.19M Shares 1,912,000 Est. Cost Unrealized
PBYI PUMA BIOTECHNOLOGY INC 0.9%
Value $80.87M Shares 2,753,425 Est. Cost Unrealized
MALLINCKRODT PUB LTD CO 0.8%
Value $80.22M Shares 1,309,000 Est. Cost Unrealized
CRVS CORVUS PHARMACEUTICALS INC 0.8%
Value $76.25M Shares 5,258,450 Est. Cost Unrealized
INSYS THERAPEUTICS INC NEW 0.8%
Value $72.88M Shares 4,557,740 Est. Cost Unrealized
NUVASIVE INC 0.8%
Value $72.34M Shares 1,487,000 Est. Cost Unrealized
HUM HUMANA INC 0.7%
Value $62.15M Shares 339,700 Est. Cost Unrealized
LOXO ONCOLOGY INC 0.6%
Value $59.49M Shares 2,175,857 Est. Cost Unrealized
JNJ JOHNSON & JOHNSON 0.6%
Value $57.54M Shares 531,800 Est. Cost Unrealized
IMMUNOGEN INC 0.5%
Value $51.94M Shares 6,095,647 Est. Cost Unrealized
SHIRE PLC 0.5%
Value $51.63M Shares 300,371 Est. Cost Unrealized
XBI SPDR SERIES TRUST 0.5%
Value $50.69M Shares 981,200 Est. Cost Unrealized
MDT MEDTRONIC PLC 0.5%
Value $49.97M Shares 666,299 Est. Cost Unrealized
GKOS GLAUKOS CORP 0.5%
Value $48.86M Shares 2,897,938 Est. Cost Unrealized
CIGNA CORPORATION 0.5%
Value $46.04M Shares 335,500 Est. Cost Unrealized
INSM INSMED INC 0.5%
Value $43.96M Shares 3,469,900 Est. Cost Unrealized
DIMENSION THERAPEUTICS INC 0.4%
Value $42.26M Shares 5,397,698 Est. Cost Unrealized
CYH COMMUNITY HEALTH SYS INC NEW 0.4%
Value $40.19M Shares 2,171,400 Est. Cost Unrealized
BLUEBIRD BIO INC 0.4%
Value $40.18M Shares 945,500 Est. Cost Unrealized
ACAD ACADIA PHARMACEUTICALS INC 0.4%
Value $39.19M Shares 1,401,600 Est. Cost Unrealized
DYNAVAX TECHNOLOGIES CORP 0.4%
Value $37.99M Shares 1,974,700 Est. Cost Unrealized
VRAYQ VIEWRAY INC 0.4%
Value $34.36M Shares 7,989,916 Est. Cost Unrealized
ARRAY BIOPHARMA INC 0.3%
Value $31.53M Shares 10,689,000 Est. Cost Unrealized
IBB ISHARES TR 0.3%
Value $29.13M Shares 111,700 Est. Cost Unrealized
OTONOMY INC 0.3%
Value $27.6M Shares 1,850,094 Est. Cost Unrealized
XENOPORT INC 0.3%
Value $27.06M Shares 6,000,400 Est. Cost Unrealized
ALLERGAN PLC 0.3%
Value $26.8M Shares 100,000 Est. Cost Unrealized
MEDIVATION INC 0.2%
Value $23.04M Shares 501,000 Est. Cost Unrealized
SYK STRYKER CORP 0.2%
Value $22.75M Shares 212,000 Est. Cost Unrealized
IMMUNOMEDICS INC 0.2%
Value $20.38M Shares 30,000,000 Est. Cost Unrealized
INFIQ INFINITY PHARMACEUTICALS INC 0.2%
Value $19.62M Shares 3,723,528 Est. Cost Unrealized
PORTOLA PHARMACEUTICALS INC 0.2%
Value $17.1M Shares 838,100 Est. Cost Unrealized
SVA SINOVAC BIOTECH LTD 0.2%
Value $17.05M Shares 2,667,500 Est. Cost Unrealized
NEWLINK GENETICS CORP 0.2%
Value $14.87M Shares 817,006 Est. Cost Unrealized
XNCR XENCOR INC 0.2%
Value $14.86M Shares 1,107,022 Est. Cost Unrealized
AFFIMED N V 0.2%
Value $14.71M Shares 3,931,800 Est. Cost Unrealized
LAB FLUIDIGM CORP DEL 0.1%
Value $14.09M Shares 1,746,100 Est. Cost Unrealized
PIERIS PHARMACEUTICALS INC 0.1%
Value $13.79M Shares 7,259,620 Est. Cost Unrealized
GW PHARMACEUTICALS PLC 0.1%
Value $13.75M Shares 190,600 Est. Cost Unrealized
CAH CARDINAL HEALTH INC 0.1%
Value $13.6M Shares 166,000 Est. Cost Unrealized
FORWARD PHARMA A/S 0.1%
Value $13.57M Shares 798,000 Est. Cost Unrealized
CYNAPSUS THERAPEUTICS INC 0.1%
Value $13.22M Shares 1,140,325 Est. Cost Unrealized
BAXALTA INC 0.1%
Value $13.17M Shares 326,000 Est. Cost Unrealized
EXAS EXACT SCIENCES CORP 0.1%
Value $12.74M Shares 1,890,400 Est. Cost Unrealized
CLOVIS ONCOLOGY INC 0.1%
Value $12.69M Shares 660,900 Est. Cost Unrealized
EHTH EHEALTH INC 0.1%
Value $12.21M Shares 1,300,000 Est. Cost Unrealized
NTRA NATERA INC 0.1%
Value $12.15M Shares 1,276,190 Est. Cost Unrealized
MCK MCKESSON CORP 0.1%
Value $12.14M Shares 77,200 Est. Cost Unrealized
NABRIVA THERAPEUTICS AG 0.1%
Value $11.78M Shares 1,315,000 Est. Cost Unrealized
JAZZ JAZZ PHARMACEUTICALS PLC 0.1%
Value $11.75M Shares 90,000 Est. Cost Unrealized
ENSG ENSIGN GROUP INC 0.1%
Value $11.64M Shares 514,200 Est. Cost Unrealized
PRQR PROQR THRAPEUTICS N V 0.1%
Value $11.25M Shares 2,305,446 Est. Cost Unrealized
MRK MERCK & CO INC NEW 0.1%
Value $11.13M Shares 210,400 Est. Cost Unrealized
HORIZON PHARMA INVT LTD 0.1%
Value $11.13M Shares 13,000,000 Est. Cost Unrealized
ZBH ZIMMER BIOMET HLDGS INC 0.1%
Value $10.98M Shares 103,000 Est. Cost Unrealized
PRONAI THERAPEUTICS INC 0.1%
Value $10.94M Shares 1,623,149 Est. Cost Unrealized
INOTEK PHARMACEUTICALS CORP 0.1%
Value $10.29M Shares 1,391,000 Est. Cost Unrealized
EW EDWARDS LIFESCIENCES CORP 0.1%
Value $10.14M Shares 115,000 Est. Cost Unrealized
SNDX SYNDAX PHARMACEUTICALS INC 0.1%
Value $10.09M Shares 757,365 Est. Cost Unrealized
ABT ABBOTT LABS 0.1%
Value $9.914M Shares 237,000 Est. Cost Unrealized
CLLS CELLECTIS S A 0.1%
Value $9.625M Shares 350,000 Est. Cost Unrealized
GLPG GALAPAGOS NV 0.1%
Value $9.619M Shares 230,000 Est. Cost Unrealized
IMMUNOMEDICS INC 0.1%
Value $9.505M Shares 3,802,000 Est. Cost Unrealized
SIENTRA INC 0.1%
Value $9.285M Shares 1,357,500 Est. Cost Unrealized
AETNA INC NEW 0.1%
Value $8.539M Shares 76,000 Est. Cost Unrealized
INTRA CELLULAR THERAPIES INC 0.1%
Value $8.173M Shares 294,000 Est. Cost Unrealized
RARE ULTRAGENYX PHARMACEUTICAL IN 0.1%
Value $8.123M Shares 128,300 Est. Cost Unrealized
ENTA ENANTA PHARMACEUTICALS INC 0.1%
Value $7.325M Shares 249,400 Est. Cost Unrealized
BIOTIE THERAPIES OYJ 0.1%
Value $7.09M Shares 268,672 Est. Cost Unrealized
ASSEMBLY BIOSCIENCES INC 0.1%
Value $7.013M Shares 1,397,100 Est. Cost Unrealized
REDHILL BIOPHARMA LTD 0.1%
Value $6.92M Shares 564,900 Est. Cost Unrealized
INCYTE CORP 0.1%
Value $6.727M Shares 4,250,000 Est. Cost Unrealized
INCYTE CORP 0.1%
Value $6.574M Shares 4,250,000 Est. Cost Unrealized
SYNERGY PHARMACEUTICALS DEL 0.1%
Value $6.284M Shares 2,276,648 Est. Cost Unrealized
MGNX MACROGENICS INC 0.1%
Value $5.944M Shares 317,000 Est. Cost Unrealized
ADVAXIS INC 0.1%
Value $5.748M Shares 636,600 Est. Cost Unrealized
QIAGEN NV 0.1%
Value $5.737M Shares 256,800 Est. Cost Unrealized
FLUIDIGM CORP DEL 0.1%
Value $5.553M Shares 10,000,000 Est. Cost Unrealized
MARINUS PHARMACEUTICALS INC 0.1%
Value $5.192M Shares 965,000 Est. Cost Unrealized
LION BIOTECHNOLOGIES INC 0.1%
Value $5.192M Shares 1,022,100 Est. Cost Unrealized
VALEANT PHARMACEUTICALS INTL 0.1%
Value $5.126M Shares 194,900 Est. Cost Unrealized
INVITAE CORP 0.0%
Value $4.672M Shares 456,666 Est. Cost Unrealized
CONNECTURE INC 0.0%
Value $4.454M Shares 1,740,000 Est. Cost Unrealized
SERES THERAPEUTICS INC 0.0%
Value $4.426M Shares 166,645 Est. Cost Unrealized
MIRATI THERAPEUTICS INC 0.0%
Value $4.234M Shares 197,859 Est. Cost Unrealized
ASND ASCENDIS PHARMA A S 0.0%
Value $4.122M Shares 222,223 Est. Cost Unrealized
ADAPY ADAPTIMMUNE THERAPEUTICS PLC 0.0%
Value $3.567M Shares 438,784 Est. Cost Unrealized
CERS CERUS CORP 0.0%
Value $3.429M Shares 578,300 Est. Cost Unrealized
MYLAN N V 0.0%
Value $3.235M Shares 69,800 Est. Cost Unrealized
ANACOR PHARMACEUTICALS INC 0.0%
Value $2.849M Shares 53,300 Est. Cost Unrealized
ALIMERA SCIENCES INC 0.0%
Value $2.625M Shares 1,500,000 Est. Cost Unrealized
ROKA BIOSCIENCE INC 0.0%
Value $2.222M Shares 3,220,429 Est. Cost Unrealized
QURE UNIQURE NV 0.0%
Value $2.195M Shares 184,800 Est. Cost Unrealized
OREXIGEN THERAPEUTICS INC 0.0%
Value $2.149M Shares 5,210,000 Est. Cost Unrealized
PORTOLA PHARMACEUTICALS INC 0.0%
Value $2.04M Shares 100,000 Est. Cost Unrealized
MEDIGUS LTD 0.0%
Value $1.608M Shares 600,000 Est. Cost Unrealized
ACHILLION PHARMACEUTICALS IN 0.0%
Value $1.544M Shares 200,000 Est. Cost Unrealized
XTANT MED HLDGS INC 0.0%
Value $1.288M Shares 475,439 Est. Cost Unrealized
FATE FATE THERAPEUTICS INC 0.0%
Value $1.247M Shares 692,900 Est. Cost Unrealized
PERNIX THERAPEUTICS HLDGS IN 0.0%
Value $1.127M Shares 1,073,000 Est. Cost Unrealized
COGENTIX MED INC 0.0%
Value $1.09M Shares 990,745 Est. Cost Unrealized
BIOLINERX LTD 0.0%
Value $1.059M Shares 1,038,600 Est. Cost Unrealized
QLT INC 0.0%
Value $995K Shares 500,000 Est. Cost Unrealized
BIOMARIN PHARMACEUTICAL INC 0.0%
Value $594K Shares 500,000 Est. Cost Unrealized
BIOMARIN PHARMACEUTICAL INC 0.0%
Value $579K Shares 500,000 Est. Cost Unrealized
AMARIN CORP PLC 0.0%
Value $536K Shares 350,000 Est. Cost Unrealized