Location: San Diego, CA
CIK: 0001232621 · Show all filings
Period: Q4 2024 (← Previous) (Next →)
Filing Date: Feb 14, 2025
Total Value: $1.511B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Share Price | Est. Cost/Share | Unrealized @ Report Date | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|---|
| TARS | TARSUS PHARMACEUTICALS INC | 2,254,797 | $125M | 8.3% | $55.37 * | $16.20 | +180.3% | COM | 87650L103 |
| AUPH | AURINIA PHARMACEUTICALS INC | 8,429,500 | $75.7M | 5.0% | $8.98 * | $6.74 | +21.0% | COM | 05156V102 |
| GLPG | GALAPAGOS NV | 2,161,200 | $59.43M | 3.9% | $27.50 | $27.81 | — | SPON ADR | 36315X101 |
| EOLS | EVOLUS INC | 4,997,399 | $55.17M | 3.7% | $11.04 * | $10.30 | +36.6% | COM | 30052C107 |
| MIRM | MIRUM PHARMACEUTICALS INC | 1,237,107 | $51.15M | 3.4% | $41.35 | $22.11 | +88.5% | COM | 604749101 |
| VRDN | VIRIDIAN THERAPEUTICS INC | 2,492,925 | $47.79M | 3.2% | $19.17 * | $16.07 | +35.3% | COM | 92790C104 |
| IMCR | IMMUNOCORE HLDGS PLC | 1,555,600 | $45.89M | 3.0% | $29.50 | $30.56 | — | ADS | 45258D105 |
| KALV | KALVISTA PHARMACEUTICALS INC | 4,893,847 | $41.45M | 2.7% | $8.47 * | $10.21 | +1.4% | COM | 483497103 |
| RLAY | RELAY THERAPEUTICS INC | 8,068,058 | $33.24M | 2.2% | $4.12 * | $6.34 | -14.2% | COM | 75943R102 |
| REPL | REPLIMUNE GROUP INC | 2,700,000 | $32.7M | 2.2% | $12.11 | $10.31 | +17.8% | COM | 76029N106 |
| PTCT | PTC THERAPEUTICS INC | 700,000 | $31.6M | 2.1% | $45.14 * | $22.87 | +87.2% | COM | 69366J200 |
| BNTX | BIONTECH SE | 270,000 | $30.77M | 2.0% | $113.95 | $118.77 | — | SPONSORED ADS | 09075V102 |
| ACAD | ACADIA PHARMACEUTICALS INC | 1,500,000 | $27.52M | 1.8% | $18.35 * | $19.28 | -16.3% | COM | 004225108 |
| — | INTRA-CELLULAR THERAPIES INC | 300,000 | $25.06M | 1.7% | $83.52 | $64.14 | — | COM | 46116X101 |
| PCVX | VAXCYTE INC | 300,000 | $24.56M | 1.6% | $81.86 * | $39.24 | +153.0% | COM | 92243G108 |
| — | DYNAVAX TECHNOLOGIES CORP | 1,850,000 | $23.62M | 1.6% | $12.77 | $11.23 | — | COM NEW | 268158201 |
| LENZ | LENZ THERAPEUTICS INC | 766,940 | $22.14M | 1.5% | $28.87 * | $19.96 | +52.7% | COM | 52635N103 |
| NBIX | NEUROCRINE BIOSCIENCES INC | 150,000 | $20.48M | 1.4% | $136.50 * | $137.09 | -9.8% | COM | 64125C109 |
| ALT | ALTIMMUNE INC | 2,750,000 | $19.83M | 1.3% | $7.21 * | $9.59 | -20.3% | COM NEW | 02155H200 |
| NVDA | NVIDIA CORPORATION | 142,569 | $19.15M | 1.3% | $134.29 * | $102.89 | +33.9% | COM | 67066G104 |
| ANAB | ANAPTYSBIO INC | 1,330,879 | $17.62M | 1.2% | $13.24 * | $21.51 | +12.6% | COM | 032724106 |
| ANIP | ANI PHARMACEUTICALS INC | 317,500 | $17.55M | 1.2% | $55.28 * | $63.41 | -9.5% | COM | 00182C103 |
| JAZZ | JAZZ PHARMACEUTICALS PLC | 140,000 | $17.24M | 1.1% | $123.15 * | $109.94 | +7.2% | SHS USD | G50871105 |
| ZYME | ZYMEWORKS INC | 1,100,000 | $16.1M | 1.1% | $14.64 * | $8.10 | +72.5% | COM | 98985Y108 |
| AVIR | ATEA PHARMACEUTICALS INC | 4,788,912 | $16.04M | 1.1% | $3.35 | $3.68 | -9.6% | COM | 04683R106 |
| — | AVADEL PHARMACEUTICALS PLC | 1,497,500 | $15.74M | 1.0% | $10.51 | $13.43 | — | COM SHS | G29687103 |
| META | META PLATFORMS INC | 26,600 | $15.57M | 1.0% | $585.51 | $486.74 | +20.1% | CL A | 30303M102 |
| LEGN | LEGEND BIOTECH CORP | 450,000 | $14.64M | 1.0% | $32.54 | $32.54 | — | SPONSORED ADS | 52490G102 |
| GSK | GSK PLC | 400,000 | $13.53M | 0.9% | $33.82 | $37.80 | — | SPONSORED ADR | 37733W204 |
| SNY | SANOFI | 270,000 | $13.02M | 0.9% | $48.23 | $50.67 | — | SPONSORED ADR | 80105N105 |
| LQDA | LIQUIDIA CORPORATION | 1,100,000 | $12.94M | 0.9% | $11.76 * | $11.76 | -7.0% | COM NEW | 53635D202 |
| VKTX | VIKING THERAPEUTICS INC | 320,000 | $12.88M | 0.9% | $40.24 * | $53.64 | +6.3% | COM | 92686J106 |
| TDOC | TELADOC HEALTH INC | 1,400,000 | $12.73M | 0.8% | $9.09 * | $11.08 | -12.8% | COM | 87918A105 |
| MRNA | MODERNA INC | 300,000 | $12.47M | 0.8% | $41.58 * | $47.80 | 0.0% | COM | 60770K107 |
| KNSA | KINIKSA PHARMACEUTICALS INTL | 628,609 | $12.43M | 0.8% | $19.78 * | $18.73 | +21.8% | ORD SHS CL A | G52694109 |
| HELP | CYBIN INC | 1,330,097 | $11.73M | 0.8% | $8.82 * | $10.08 | +0.8% | COM NEW | 23256X407 |
| VNDA | VANDA PHARMACEUTICALS INC | 2,353,307 | $11.27M | 0.7% | $4.79 | $4.32 | +11.1% | COM | 921659108 |
| CGEM | CULLINAN THERAPEUTICS INC | 921,138 | $11.22M | 0.7% | $12.18 * | $14.78 | -2.7% | COM | 230031106 |
| CRSP | CRISPR THERAPEUTICS AG | 266,500 | $10.49M | 0.7% | $39.36 * | $56.80 | -16.9% | NAMEN AKT | H17182108 |
| NUVB | NUVATION BIO INC | 3,900,000 | $10.37M | 0.7% | $2.66 * | $1.45 | +77.2% | COM CL A | 67080N101 |
| — | HILLEVAX INC | 4,920,000 | $10.18M | 0.7% | $2.07 | $1.76 | — | COM | 43157M102 |
| AZN | ASTRAZENECA PLC | 150,000 | $9.828M | 0.7% | $65.52 | $56.36 | — | SPONSORED ADR | 046353108 |
| ELAN | ELANCO ANIMAL HEALTH INC | 800,000 | $9.688M | 0.6% | $12.11 * | $13.72 | -4.6% | COM | 28414H103 |
| HRMY | HARMONY BIOSCIENCES HLDGS IN | 281,200 | $9.676M | 0.6% | $34.41 | $41.26 | -16.7% | COM | 413197104 |
| ADMA | ADMA BIOLOGICS INC | 550,000 | $9.432M | 0.6% | $17.15 * | $18.81 | 0.0% | COM | 000899104 |
| RCKT | ROCKET PHARMACEUTICALS INC | 750,000 | $9.428M | 0.6% | $12.57 * | $24.86 | -39.5% | COM | 77313F106 |
| — | CARGO THERAPEUTICS INC | 640,000 | $9.229M | 0.6% | $14.42 | $20.91 | — | COM | 14179K101 |
| DSGN | DESIGN THERAPEUTICS INC | 1,480,975 | $9.138M | 0.6% | $6.17 * | $4.45 | +29.9% | COM | 25056L103 |
| CMPX | COMPASS THERAPEUTICS INC | 5,900,000 | $8.555M | 0.6% | $1.45 * | $1.53 | +8.3% | COM | 20454B104 |
| BLCO | BAUSCH PLUS LOMB CORP | 450,000 | $8.127M | 0.5% | $18.06 * | $17.19 | +13.5% | COMMON SHARES | 071705107 |
| EWTX | EDGEWISE THERAPEUTICS INC COM | 300,000 | $8.01M | 0.5% | $26.70 * | $31.84 | 0.0% | COM | 28036F105 |
| — | ADICET BIO INC | 8,145,988 | $7.836M | 0.5% | $0.96 | $2.54 | — | COM | 007002108 |
| — | ESSA PHARMA INC | 4,300,000 | $7.697M | 0.5% | $1.79 | $1.79 | — | COM NEW | 29668H708 |
| BIOA | BIOAGE LABS INC | 1,318,361 | $7.633M | 0.5% | $5.79 * | $17.24 | 0.0% | COM | 09077V100 |
| ABCL | ABCELLERA BIOLOGICS INC | 2,582,816 | $7.568M | 0.5% | $2.93 * | $2.95 | -5.7% | COM | 00288U106 |
| CTMX | CYTOMX THERAPEUTICS INC | 7,311,760 | $7.531M | 0.5% | $1.03 | $1.90 | -43.4% | COM | 23284F105 |
| — | SINGULAR GENOMICS SYSTEMS IN | 372,000 | $7.228M | 0.5% | $19.43 | $15.67 | — | COM NEW | 82933R308 |
| IBRX | IMMUNITYBIO INC | 2,814,192 | $7.204M | 0.5% | $2.56 * | $4.17 | 0.0% | COM | 45256X103 |
| INSM | INSMED INC | 100,000 | $6.904M | 0.5% | $69.04 * | $38.78 | +85.7% | COM PAR $.01 | 457669307 |
| ONC | BEIGENE LTD | 37,000 | $6.834M | 0.5% | $184.71 | $134.82 | — | SPONSORED ADR | 07725L102 |
| VTYX | VENTYX BIOSCIENCES INC | 3,100,000 | $6.789M | 0.4% | $2.19 * | $7.75 | -70.8% | COM | 92332V107 |
| DERM | JOURNEY MED CORP | 1,725,569 | $6.747M | 0.4% | $3.91 * | $5.46 | 0.0% | COM | 48115J109 |
| BCRX | BIOCRYST PHARMACEUTICALS INC | 800,000 | $6.016M | 0.4% | $7.52 | $9.70 | -21.7% | COM | 09058V103 |
| DNTH | DIANTHUS THERAPEUTICS INC | 264,692 | $5.77M | 0.4% | $21.80 * | $12.62 | +103.8% | COM | 252828108 |
| NKTX | NKARTA INC | 2,293,719 | $5.711M | 0.4% | $2.49 * | $5.12 | -39.7% | COM | 65487U108 |
| ALXO | ALX ONCOLOGY HLDGS INC | 3,296,883 | $5.506M | 0.4% | $1.67 * | $3.72 | -58.7% | COM | 00166B105 |
| BIIB | BIOGEN INC | 35,000 | $5.352M | 0.4% | $152.92 * | $217.32 | -22.4% | COM | 09062X103 |
| IONS | IONIS PHARMACEUTICALS INC | 150,000 | $5.244M | 0.3% | $34.96 * | $32.73 | +14.2% | COM | 462222100 |
| BHVN | BIOHAVEN LTD | 140,000 | $5.229M | 0.3% | $37.35 * | $14.12 | +230.4% | COM | G1110E107 |
| SEER | SEER INC | 2,194,423 | $5.069M | 0.3% | $2.31 * | $1.85 | +18.8% | COM CL A | 81578P106 |
| CHRS | COHERUS BIOSCIENCES INC | 3,650,000 | $5.037M | 0.3% | $1.38 * | $1.47 | -23.5% | COM | 19249H103 |
| KZR | KEZAR LIFE SCIENCES INC | 720,000 | $4.838M | 0.3% | $6.72 * | $7.45 | 0.0% | COM NEW | 49372L209 |
| NVAX | NOVAVAX INC | 600,000 | $4.824M | 0.3% | $8.04 * | $12.91 | -25.3% | COM NEW | 670002401 |
| ALMS | ALUMIS INC | 600,000 | $4.716M | 0.3% | $7.86 * | $11.52 | -13.0% | COM | 022307102 |
| CYTK | CYTOKINETICS INC | 100,000 | $4.704M | 0.3% | $47.04 * | $36.21 | +43.4% | COM NEW | 23282W605 |
| APGE | APOGEE THERAPEUTICS INC | 100,000 | $4.53M | 0.3% | $45.30 * | $43.66 | +16.8% | COM | 03770N101 |
| LNTH | LANTHEUS HLDGS INC | 50,000 | $4.473M | 0.3% | $89.46 * | $58.85 | +65.5% | COM | 516544103 |
| BDTX | BLACK DIAMOND THERAPEUTICS I | 2,070,209 | $4.43M | 0.3% | $2.14 * | $2.72 | +5.4% | COM | 09203E105 |
| RVMD | REVOLUTION MEDICINES INC | 100,000 | $4.374M | 0.3% | $43.74 * | $50.47 | 0.0% | COM | 76155X100 |
| — | MERUS N V | 100,000 | $4.205M | 0.3% | $42.05 | $59.17 | — | COM | N5749R100 |
| PHAT | PHATHOM PHARMACEUTICALS INC | 500,000 | $4.06M | 0.3% | $8.12 * | $12.38 | 0.0% | COM | 71722W107 |
| NUVL | NUVALENT INC | 50,000 | $3.914M | 0.3% | $78.28 * | $82.95 | +12.6% | COM | 670703107 |
| ARE | ALEXANDRIA REAL ESTATE EQ IN | 40,000 | $3.902M | 0.3% | $97.55 * | $108.07 | -6.0% | COM | 015271109 |
| CMPS | COMPASS PATHWAYS PLC | 1,000,000 | $3.78M | 0.3% | $3.78 | $3.78 | — | SPONSORED ADS | 20451W101 |
| IOVA | IOVANCE BIOTHERAPEUTICS INC | 500,000 | $3.7M | 0.2% | $7.40 * | $5.23 | +77.2% | COM | 462260100 |
| TECX | TECTONIC THERAPEUTIC INC | 79,166 | $3.655M | 0.2% | $46.17 * | $15.77 | +168.1% | COM | 878972108 |
| GRAL | GRAIL INC | 200,000 | $3.57M | 0.2% | $17.85 * | $16.26 | 0.0% | COM | 384747101 |
| STOK | STOKE THERAPEUTICS INC | 300,000 | $3.309M | 0.2% | $11.03 * | $12.29 | 0.0% | COM | 86150R107 |
| HRTX | HERON THERAPEUTICS INC | 2,140,271 | $3.275M | 0.2% | $1.53 * | $3.99 | -59.3% | COM | 427746102 |
| CCCC | C4 THERAPEUTICS INC | 900,000 | $3.24M | 0.2% | $3.60 * | $5.77 | -13.9% | COM STK | 12529R107 |
| FATE | FATE THERAPEUTICS INC | 1,855,954 | $3.062M | 0.2% | $1.65 * | $3.85 | -34.5% | COM | 31189P102 |
| TGTX | TG THERAPEUTICS INC | 100,000 | $3.01M | 0.2% | $30.10 * | $13.94 | +105.9% | COM | 88322Q108 |
| CRBP | CORBUS PHARMACEUTICALS HLDGS | 242,653 | $2.863M | 0.2% | $11.80 * | $51.17 | -67.2% | COM NEW | 21833P301 |
| — | SPRINGWORKS THERAPEUTICS INC | 74,265 | $2.683M | 0.2% | $36.13 | $32.04 | — | COM | 85205L107 |
| — | ELEVATION ONCOLOGY INC | 4,760,000 | $2.678M | 0.2% | $0.56 | $1.20 | — | COM | 28623U101 |
| JANX | JANUX THERAPEUTICS INC | 50,000 | $2.677M | 0.2% | $53.54 | $52.89 | 0.0% | COM | 47103J105 |
| DTIL | PRECISION BIOSCIENCES INC | 673,332 | $2.565M | 0.2% | $3.81 * | $11.85 | -38.4% | COM NEW | 74019P207 |
| OKUR | ONKURE THERAPEUTICS INC | 294,626 | $2.534M | 0.2% | $8.60 * | $15.14 | 0.0% | COM CL A | 68277Q105 |
| TBPH | THERAVANCE BIOPHARMA INC | 262,896 | $2.474M | 0.2% | $9.41 * | $8.66 | +5.0% | COM | G8807B106 |
| ATYR | ATYR PHARMA INC | 671,134 | $2.43M | 0.2% | $3.62 * | $2.59 | +16.9% | COM NEW | 002120202 |
| SLNO | SOLENO THERAPEUTICS INC | 50,000 | $2.248M | 0.1% | $44.95 * | $51.81 | 0.0% | COM | 834203309 |
| CDNA | CAREDX INC | 100,000 | $2.141M | 0.1% | $21.41 * | $24.32 | 0.0% | COM | 14167L103 |
| GMAB | GENMAB A/S | 100,000 | $2.087M | 0.1% | $20.87 | $29.91 | — | SPONSORED ADS | 372303206 |
| — | APPLIED THERAPEUTICS INC | 2,428,169 | $2.079M | 0.1% | $0.86 | $6.97 | — | COM | 03828A101 |
| IDXX | IDEXX LABS INC | 5,000 | $2.067M | 0.1% | $413.44 * | $438.63 | 0.0% | COM | 45168D104 |
| — | BOLT BIOTHERAPEUTICS INC | 3,812,773 | $2.04M | 0.1% | $0.54 | $1.28 | — | COM | 097702104 |
| FTRE | FORTREA HLDGS INC | 100,000 | $1.865M | 0.1% | $18.65 * | $19.49 | 0.0% | COMMON STOCK | 34965K107 |
| — | ITEOS THERAPEUTICS INC | 221,716 | $1.703M | 0.1% | $7.68 | $10.21 | — | COM | 46565G104 |
| JPM | JPMORGAN CHASE & CO. | 6,601 | $1.582M | 0.1% | $239.73 * | $207.37 | +10.0% | COM | 46625H100 |
| WMT | WALMART INC | 17,423 | $1.574M | 0.1% | $90.35 * | $73.38 | +16.9% | COM | 931142103 |
| — | THIRD HARMONIC BIO INC | 150,000 | $1.544M | 0.1% | $10.29 | $10.29 | — | COM | 88427A107 |
| ERAS | ERASCA INC | 602,915 | $1.513M | 0.1% | $2.51 * | $2.25 | +22.0% | COM | 29479A108 |
| V | VISA INC | 4,718 | $1.491M | 0.1% | $316.01 * | $277.49 | +7.5% | COM CL A | 92826C839 |
| DIS | DISNEY WALT CO | 13,095 | $1.458M | 0.1% | $111.35 * | $97.10 | +6.6% | COM | 254687106 |
| MSFT | MICROSOFT CORP | 3,413 | $1.438M | 0.1% | $421.46 | $421.45 | +0.2% | COM | 594918104 |
| REGN | REGENERON PHARMACEUTICALS | 2,000 | $1.425M | 0.1% | $712.33 * | $834.60 | 0.0% | COM | 75886F107 |
| VTRS | VIATRIS INC | 114,316 | $1.423M | 0.1% | $12.45 * | $10.99 | +5.8% | COM | 92556V106 |
| BRK/B | BERKSHIRE HATHAWAY INC DEL | 3,099 | $1.405M | 0.1% | $453.26 | $440.92 | +4.7% | CL B NEW | 084670702 |
| VSTM | VERASTEM INC | 270,000 | $1.396M | 0.1% | $5.17 * | $6.94 | -43.3% | COM NEW | 92337C203 |
| — | MIND MEDICINE MINDMED INC | 200,000 | $1.392M | 0.1% | $6.96 | $6.96 | — | COM NEW | 60255C885 |
| PYPL | PAYPAL HLDGS INC | 15,714 | $1.341M | 0.1% | $85.35 | $71.77 | +16.9% | COM | 70450Y103 |
| PG | PROCTER AND GAMBLE CO | 7,962 | $1.335M | 0.1% | $167.65 | $163.40 | +1.4% | COM | 742718109 |
| SNDX | SYNDAX PHARMACEUTICALS INC | 100,000 | $1.322M | 0.1% | $13.22 * | $17.11 | 0.0% | COM | 87164F105 |
| HD | HOME DEPOT INC | 3,353 | $1.304M | 0.1% | $388.97 * | $360.85 | +10.1% | COM | 437076102 |
| BEAM | BEAM THERAPEUTICS INC | 50,000 | $1.24M | 0.1% | $24.80 * | $24.56 | +3.9% | COM | 07373V105 |
| VZ | VERIZON COMMUNICATIONS INC | 30,877 | $1.235M | 0.1% | $39.99 | $38.40 | +2.6% | COM | 92343V104 |
| TXN | TEXAS INSTRS INC | 6,568 | $1.232M | 0.1% | $187.51 * | $189.94 | +1.7% | COM | 882508104 |
| KO | COCA COLA CO | 19,714 | $1.227M | 0.1% | $62.26 | $63.47 | -0.6% | COM | 191216100 |
| UAL | UNITED AIRLS HLDGS INC | 12,392 | $1.203M | 0.1% | $97.10 * | $72.59 | +16.5% | COM | 910047109 |
| NFLX | NETFLIX INC | 1,344 | $1.198M | 0.1% | $891.33 * | $76.00 | +8.3% | COM | 64110L106 |
| NKE | NIKE INC | 15,789 | $1.195M | 0.1% | $75.67 | $76.20 | +0.4% | CL B | 654106103 |
| XOM | EXXON MOBIL CORP | 11,053 | $1.189M | 0.1% | $107.57 * | $110.89 | +1.3% | COM | 30231G102 |
| ULTA | ULTA BEAUTY INC | 2,699 | $1.174M | 0.1% | $434.92 * | $387.42 | 0.0% | COM | 90384S303 |
| UNH | UNITEDHEALTH GROUP INC | 2,308 | $1.168M | 0.1% | $505.95 * | $550.06 | +0.5% | COM | 91324P102 |
| JNJ | JOHNSON & JOHNSON | 7,959 | $1.151M | 0.1% | $144.62 * | $151.52 | -1.3% | COM | 478160104 |
| PFE | PFIZER INC | 42,908 | $1.138M | 0.1% | $26.53 * | $26.06 | -3.6% | COM | 717081103 |
| AXP | AMERICAN EXPRESS CO | 3,799 | $1.128M | 0.1% | $296.79 * | $268.75 | +5.5% | COM | 025816109 |
| INTC | INTEL CORP | 55,997 | $1.123M | 0.1% | $20.05 * | $25.08 | -10.1% | COM | 458140100 |
| BA | BOEING CO | 6,294 | $1.114M | 0.1% | $176.99 * | $156.93 | 0.0% | COM | 097023105 |
| AMZN | AMAZON COM INC | 5,071 | $1.113M | 0.1% | $219.40 * | $199.79 | +2.4% | COM | 023135106 |
| OPRX | OPTIMIZERX CORP | 221,200 | $1.075M | 0.1% | $4.86 * | $5.59 | 0.0% | COM NEW | 68401U204 |
| OABI | OMNIAB INC | 300,000 | $1.062M | 0.1% | $3.54 * | $4.56 | -13.2% | COM | 68218J103 |
| ALL | ALLSTATE CORP | 5,319 | $1.025M | 0.1% | $192.79 | $183.11 | +3.7% | COM | 020002101 |
| ATRA | ATARA BIOTHERAPEUTICS INC | 75,196 | $1.001M | 0.1% | $13.31 * | $15.04 | -29.9% | COM NEW | 046513206 |
| HRL | HORMEL FOODS CORP | 31,741 | $996K | 0.1% | $31.37 * | $30.03 | 0.0% | COM | 440452100 |
| TMUS | T-MOBILE US INC | 4,509 | $995K | 0.1% | $220.75 | $214.87 | +4.0% | COM | 872590104 |
| HPE | HEWLETT PACKARD ENTERPRISE C | 46,391 | $990K | 0.1% | $21.35 * | $20.44 | 0.0% | COM | 42824C109 |
| GE | GE AEROSPACE | 5,911 | $986K | 0.1% | $166.80 * | $172.66 | +2.6% | COM NEW | 369604301 |
| PAYX | PAYCHEX INC | 6,973 | $978K | 0.1% | $140.23 * | $137.31 | 0.0% | COM | 704326107 |
| CLX | CLOROX CO DEL | 6,014 | $977K | 0.1% | $162.40 * | $154.04 | +2.2% | COM | 189054109 |
| MCD | MCDONALDS CORP | 3,365 | $975K | 0.1% | $289.90 | $290.22 | 0.0% | COM | 580135101 |
| WHR | WHIRLPOOL CORP | 8,510 | $974K | 0.1% | $114.48 * | $110.34 | 0.0% | COM | 963320106 |
| — | KRONOS BIO INC | 1,003,382 | $953K | 0.1% | $0.95 | $0.95 | — | COM | 50107A104 |
| SEE | SEALED AIR CORP NEW | 28,132 | $952K | 0.1% | $33.83 * | $34.70 | 0.0% | COM | 81211K100 |
| FDX | FEDEX CORP | 3,349 | $942K | 0.1% | $281.34 * | $271.73 | 0.0% | COM | 31428X106 |
| SHW | SHERWIN WILLIAMS CO | 2,765 | $940K | 0.1% | $339.87 * | $364.13 | +1.5% | COM | 824348106 |
| IPSC | CENTURY THERAPEUTICS INC | 900,000 | $909K | 0.1% | $1.01 * | $1.82 | -25.3% | COM | 15673T100 |
| — | ASTRIA THERAPEUTICS INC | 100,000 | $894K | 0.1% | $8.94 | $9.10 | — | COM | 04635X102 |
| GEV | GE VERNOVA INC | 2,710 | $891K | 0.1% | $328.92 * | $311.89 | 0.0% | COM | 36828A101 |
| — | MARINUS PHARMACEUTICALS INC | 1,641,945 | $879K | 0.1% | $0.54 | $1.17 | — | COM NEW | 56854Q200 |
| KURA | KURA ONCOLOGY INC | 100,000 | $871K | 0.1% | $8.71 * | $19.44 | -26.0% | COM | 50127T109 |
| CVX | CHEVRON CORP NEW | 5,978 | $866K | 0.1% | $144.84 | $145.50 | 0.0% | COM | 166764100 |
| — | PASSAGE BIO INC | 1,500,000 | $851K | 0.1% | $0.57 | $0.99 | — | COM | 702712100 |
| F | FORD MTR CO | 85,749 | $849K | 0.1% | $9.90 | $10.06 | -1.9% | COM | 345370860 |
| BCAB | BIOATLA INC | 1,374,076 | $812K | 0.1% | $0.59 * | $4.72 | -64.4% | COM | 09077B104 |
| ENTA | ENANTA PHARMACEUTICALS INC | 126,655 | $728K | 0.0% | $5.75 * | $9.32 | +2.9% | COM | 29251M106 |
| LAB | STANDARD BIOTOOLS INC | 407,755 | $714K | 0.0% | $1.75 * | $1.96 | -4.9% | COM | 34385P108 |
| MGNX | MACROGENICS INC | 218,856 | $711K | 0.0% | $3.25 * | $9.74 | -63.0% | COM | 556099109 |
| LXRX | LEXICON PHARMACEUTICALS INC | 850,268 | $628K | 0.0% | $0.74 * | $1.28 | -5.2% | COM NEW | 528872302 |
| PBYI | PUMA BIOTECHNOLOGY INC | 200,000 | $610K | 0.0% | $3.05 * | $4.39 | -33.7% | COM | 74587V107 |
| — | NEXTCURE INC | 700,000 | $540K | 0.0% | $0.77 | $1.49 | — | COM | 65343E108 |
| EDIT | EDITAS MEDICINE INC | 400,000 | $508K | 0.0% | $1.27 * | $2.55 | 0.0% | COM | 28106W103 |
| — | ALLAKOS INC | 378,552 | $458K | 0.0% | $1.21 | $1.14 | — | COM | 01671P100 |
| AMLX | AMYLYX PHARMACEUTICALS INC | 100,000 | $378K | 0.0% | $3.78 * | $15.33 | -69.3% | COM | 03237H101 |
| TCRX | TSCAN THERAPEUTICS INC | 117,847 | $358K | 0.0% | $3.04 * | $4.53 | 0.0% | COM | 89854M101 |
| — | ATHIRA PHARMA INC | 600,000 | $352K | 0.0% | $0.59 | $2.66 | — | COM | 04746L104 |
| OTLK | OUTLOOK THERAPEUTICS INC | 182,502 | $345K | 0.0% | $1.89 * | $8.09 | -49.1% | COM | 69012T305 |
| RVPH | REVIVA PHARMACEUTCLS HLDGS I | 170,000 | $308K | 0.0% | $1.81 * | $1.39 | 0.0% | COM | 76152G100 |
| — | ALLOVIR INC | 552,264 | $232K | 0.0% | $0.42 | $0.42 | — | COM | 019818103 |
| AFMDQ | AFFIMED N V | 148,315 | $176K | 0.0% | $1.19 * | $4.41 | -36.5% | ORDINARY SHS NEW | N01045207 |
| IVVD | INVIVYD INC | 330,172 | $146K | 0.0% | $0.44 * | $1.77 | -55.9% | COM | 00534A102 |
| RLMD | RELMADA THERAPEUTICS INC | 200,825 | $104K | 0.0% | $0.52 * | $2.74 | -10.9% | COM | 75955J402 |
| IMRX | IMMUNEERING CORP | 12,073 | $26,561 | 0.0% | $2.20 * | $2.07 | 0.0% | CLASS A COM | 45254E107 |