Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
—	ISHARES TR	8,000	$99.5M	10.4%	—	—	Put	464287955
—	SPDR S&P 500 ETF TR	3,500	$72.25M	7.5%	—	—	Put	78462F953
—	ACTAVIS PLC	192,100	$57.17M	6.0%	$266.21	—	SHS	G0083B108
PFE	PFIZER INC	1,024,013	$35.63M	3.7%	$17.96	+11.9%	COM	717081103
—	SPDR SERIES TRUST	1,500	$33.06M	3.4%	—	—	Put	78464A950
GILD	GILEAD SCIENCES INC	320,000	$31.4M	3.3%	$71.32	-1.1%	COM	375558103
TEVA	TEVA PHARMACEUTICAL INDS LTD	402,819	$25.1M	2.6%	$51.86	—	ADR	881624209
ABBV	ABBVIE INC	407,000	$23.83M	2.5%	$38.85	0.0%	COM	00287Y109
—	TEVA PHARMACEUTICAL INDS LTD	3,500	$21.8M	2.3%	—	—	Call	881624909
MRK	MERCK & CO INC NEW	375,000	$21.55M	2.2%	$40.30	0.0%	COM	58933Y105
AMGN	AMGEN INC	120,200	$19.21M	2.0%	$115.04	0.0%	COM	031162100
—	ENDO INTL PLC	210,000	$18.84M	2.0%	$89.70	—	SHS	G30401106
—	MYLAN N V	272,100	$16.15M	1.7%	$59.35	—	SHS EURO	N59465109
—	AUSPEX PHARMACEUTICALS INC	125,074	$12.54M	1.3%	$34.61	—	COM	05211J102
ORA	ORMAT TECHNOLOGIES INC	80,092	$12.05M	1.3%	$25.22	+14.9%	COM	686688102
—	AMAG PHARMACEUTICALS INC	200,230	$10.95M	1.1%	$40.43	—	COM	00163U106
—	ISHARES TR	300	$10.3M	1.1%	—	—	Put	464287956
BMRN	BIOMARIN PHARMACEUTICAL INC	80,000	$9.97M	1.0%	$60.50	+75.1%	COM	09061G101
NVS	NOVARTIS A G	100,000	$9.861M	1.0%	$84.65	—	SPONSORED ADR	66987V109
—	SELECT SECTOR SPDR TR	1,300	$9.425M	1.0%	—	—	Put	81369Y959
—	VALEANT PHARMACEUTICALS INTL	45,750	$9.087M	0.9%	$131.20	—	COM	91911K102
UTHR	UNITED THERAPEUTICS CORP DEL	48,840	$8.422M	0.9%	$103.09	+47.9%	COM	91307C102
—	CLOVIS ONCOLOGY INC	112,455	$8.348M	0.9%	$55.55	—	COM	189464100
—	CELGENE CORP	70,000	$8.07M	0.8%	$115.29	—	COM	151020104
—	VERINT SYS INC	122,304	$7.574M	0.8%	$49.78	—	COM	92343X100
—	SHIRE PLC	134,751	$7.229M	0.8%	$80.71	—	SPONSORED ADR	82481R106
—	SEATTLE GENETICS INC	200,000	$7.07M	0.7%	$35.35	—	COM	812578102
IWM	ISHARES TR	56,100	$6.977M	0.7%	$119.77	—	RUSSELL 2000 ETF	464287655
—	ARRAY BIOPHARMA INC	923,922	$6.809M	0.7%	$3.98	—	COM	04269X105
BMY	BRISTOL MYERS SQUIBB CO	100,000	$6.45M	0.7%	$38.91	+11.7%	COM	110122108
—	DYAX CORP	367,556	$6.158M	0.6%	$10.57	—	COM	26746E103
AZN	ASTRAZENECA PLC	86,637	$5.929M	0.6%	$68.43	—	SPONSORED ADR	046353108
CHKP	CHECK POINT SOFTWARE TECH LT	71,927	$5.896M	0.6%	$80.78	0.0%	ORD	M22465104
—	INSYS THERAPEUTICS INC NEW	100,000	$5.813M	0.6%	$58.13	—	COM NEW	45824V209
—	BELLICUM PHARMACEUTICALS INC	249,567	$5.693M	0.6%	$22.81	—	COM	079481107
—	CONCERT PHARMACEUTICALS INC	375,000	$5.679M	0.6%	$14.37	—	COM	206022105
AAPL	APPLE INC	42,733	$5.317M	0.6%	$26.84	0.0%	COM	037833100
—	TEKMIRA PHARMACEUTICALS CORP	298,486	$5.212M	0.5%	$16.11	—	COM NEW	87911B209
INSM	INSMED INC	250,000	$5.2M	0.5%	$17.62	0.0%	COM PAR $.01	457669307
KMDA	KAMADA LTD	293,727	$5.167M	0.5%	$3.69	+13.2%	SHS	M6240T109
—	FORWARD PHARMA A/S	180,000	$5.098M	0.5%	$20.83	—	SPONSORED ADR	34986J105
—	TOWERS WATSON & CO	38,300	$5.063M	0.5%	$107.27	—	CL A	891894107
VNDA	VANDA PHARMACEUTICALS INC	543,390	$5.054M	0.5%	$11.84	-4.6%	COM	921659108
FOLD	AMICUS THERAPEUTICS INC	450,000	$4.896M	0.5%	$6.86	+28.4%	COM	03152W109
—	RELYPSA INC	135,000	$4.869M	0.5%	$24.13	—	COM	759531106
CPRX	CATALYST PHARM PARTNERS INC	1,100,000	$4.763M	0.5%	$2.69	+33.8%	COM	14888U101
—	APPLIED GENETIC TECHNOL CORP	235,124	$4.7M	0.5%	$19.02	—	COM	03820J100
—	IMPAX LABORATORIES INC	100,000	$4.687M	0.5%	$46.87	—	COM	45256B101
—	MEDIVATION INC	36,115	$4.661M	0.5%	$77.09	—	COM	58501N101
—	KYTHERA BIOPHARMACEUTICALS I	90,000	$4.514M	0.5%	$50.16	—	COM	501570105
—	DEPOMED INC	200,000	$4.482M	0.5%	$22.41	—	COM	249908104
—	BROADCOM CORP	100,800	$4.364M	0.5%	$33.39	—	CL A	111320107
CVS	CVS HEALTH CORP	42,260	$4.362M	0.5%	$57.05	+30.2%	COM	126650100
XLV	SELECT SECTOR SPDR TR	59,853	$4.339M	0.5%	$61.55	—	SBI HEALTHCARE	81369Y209
—	ALEXION PHARMACEUTICALS INC	25,000	$4.333M	0.5%	$173.32	—	COM	015351109
—	ALDER BIOPHARMACEUTICALS INC	150,000	$4.329M	0.5%	$28.86	—	COM	014339105
PTCT	PTC THERAPEUTICS INC	70,000	$4.26M	0.4%	$30.94	+97.2%	COM	69366J200
—	INTERCEPT PHARMACEUTICALS IN	15,000	$4.23M	0.4%	$251.78	—	COM	45845P108
BIIB	BIOGEN INC	10,000	$4.222M	0.4%	$323.51	+21.8%	COM	09062X103
SBUX	STARBUCKS CORP	87,308	$4.134M	0.4%	$34.79	+3.8%	COM	855244109
AOS	SMITH A O	61,600	$4.045M	0.4%	$25.54	0.0%	COM	831865209
—	KITE PHARMA INC	65,970	$3.805M	0.4%	$39.80	—	COM	49803L109
—	PORTOLA PHARMACEUTICALS INC	100,023	$3.797M	0.4%	$31.21	—	COM	737010108
—	ARIAD PHARMACEUTICALS INC	445,000	$3.667M	0.4%	$8.24	—	COM	04033A100
—	PTC THERAPEUTICS INC	600	$3.651M	0.4%	—	—	Call	69366J900
FEZ	SPDR INDEX SHS FDS	94,000	$3.649M	0.4%	$38.82	—	EURO STOXX 50	78463X202
—	INTRA CELLULAR THERAPIES INC	150,000	$3.582M	0.4%	$23.88	—	COM	46116X101
PRTA	PROTHENA CORP PLC	88,133	$3.361M	0.3%	$22.36	+14.7%	SHS	G72800108
—	DYAX CORP	2,000	$3.351M	0.3%	—	—	Put	26746E953
ESPR	ESPERION THERAPEUTICS INC NE	36,000	$3.334M	0.3%	$64.53	0.0%	COM	29664W105
TJX	TJX COS INC NEW	47,330	$3.315M	0.3%	$26.63	+9.9%	COM	872540109
—	SAGE THERAPEUTICS INC	65,724	$3.301M	0.3%	$31.50	—	COM	78667J108
PBYI	PUMA BIOTECHNOLOGY INC	13,796	$3.257M	0.3%	$94.57	+126.0%	COM	74587V107
EWG	ISHARES	108,000	$3.223M	0.3%	$29.84	—	MSCI GERMANY ETF	464286806
—	GW PHARMACEUTICALS PLC	35,000	$3.19M	0.3%	$91.14	—	ADS	36197T103
—	SUNESIS PHARMACEUTICALS INC	1,300,000	$3.185M	0.3%	$2.45	—	COM NEW	867328601
VFC	V F CORP	42,170	$3.176M	0.3%	$69.22	0.0%	COM	918204108
—	ORBOTECH LTD	196,622	$3.152M	0.3%	$14.74	—	ORD	M75253100
—	AEGERION PHARMACEUTICALS INC	120,000	$3.14M	0.3%	$20.94	—	COM	00767E102
PRGO	PERRIGO CO PLC	18,400	$3.046M	0.3%	$159.50	0.0%	SHS	G97822103
NBIX	NEUROCRINE BIOSCIENCES INC	75,000	$2.978M	0.3%	$24.55	+45.7%	COM	64125C109
—	MIRATI THERAPEUTICS INC	100,000	$2.932M	0.3%	$29.32	—	COM	60468T105
—	KERYX BIOPHARMACEUTICALS INC	230,000	$2.928M	0.3%	$13.96	—	COM	492515101
—	CELLDEX THERAPEUTICS INC NEW	105,000	$2.926M	0.3%	$27.87	—	COM	15117B103
—	RECEPTOS INC	17,500	$2.886M	0.3%	$55.92	—	COM	756207106
—	AERIE PHARMACEUTICALS INC	90,000	$2.821M	0.3%	$19.11	—	COM	00771V108
—	EPIZYME INC	150,000	$2.817M	0.3%	$18.78	—	COM	29428V104
—	MEDICINES CO	1,000	$2.802M	0.3%	—	—	Call	584688905
—	MEDICINES CO	100,000	$2.802M	0.3%	$27.67	—	COM	584688105
—	TETRAPHASE PHARMACEUTICALS I	75,000	$2.748M	0.3%	$36.64	—	COM	88165N105
—	IMMUNE DESIGN CORP	129,440	$2.732M	0.3%	$21.11	—	COM	45252L103
—	RETROPHIN INC	111,392	$2.669M	0.3%	$23.96	—	COM	761299106
—	ATARA BIOTHERAPEUTICS INC	63,579	$2.643M	0.3%	$41.57	—	COM	046513107
—	VERIFONE SYS INC	75,545	$2.636M	0.3%	$34.89	—	COM	92342Y109
—	TREVENA INC	391,811	$2.555M	0.3%	$6.76	—	COM	89532E109
QURE	UNIQURE NV	102,415	$2.491M	0.3%	$12.24	+78.3%	SHS	N90064101
—	OTONOMY INC	70,000	$2.475M	0.3%	$35.36	—	COM	68906L105
—	AVALANCHE BIOTECHNOLOGIES IN	60,000	$2.431M	0.3%	$40.52	—	COM	05337G107
SNA	SNAP ON INC	15,340	$2.256M	0.2%	$96.54	+13.4%	COM	833034101
—	THERAPEUTICSMD INC	365,000	$2.208M	0.2%	$6.05	—	COM	88338N107
SGMO	SANGAMO BIOSCIENCES INC	140,000	$2.195M	0.2%	$12.14	+27.4%	COM	800677106
—	SUMMIT THERAPEUTICS PLC	175,000	$2.168M	0.2%	$12.39	—	SPONS ADS	86627R102
—	INOTEK PHARMACEUTICALS CORP	400,000	$2.168M	0.2%	$5.42	—	COM	45780V102
ITB	ISHARES	76,000	$2.145M	0.2%	$28.22	—	US HOME CONS ETF	464288752
—	PRICELINE GRP INC	1,820	$2.119M	0.2%	$1164.29	—	COM NEW	741503403
WAB	WABTEC CORP	21,500	$2.043M	0.2%	$84.86	0.0%	COM	929740108
—	STERICYCLE INC	14,500	$2.036M	0.2%	$140.41	—	COM	858912108
—	TRILLIUM THERAPEUTICS INC	95,000	$1.922M	0.2%	$20.23	—	COM NEW	89620X506
—	MARINUS PHARMACEUTICALS INC	213,533	$1.92M	0.2%	$6.47	—	COM	56854Q101
UNP	UNION PAC CORP	17,489	$1.894M	0.2%	$80.32	+14.4%	COM	907818108
ELLO	ELLOMAY CAPITAL LIMITED	221,678	$1.884M	0.2%	$9.45	-5.7%	SHS	M39927120
MGNX	MACROGENICS INC	60,000	$1.882M	0.2%	$26.30	+28.9%	COM	556099109
—	ZOSANO PHARMA CORP	184,619	$1.866M	0.2%	$10.11	—	COM	98979H103
—	TRANSITION THERAPEUTICS INC	272,906	$1.864M	0.2%	$6.83	—	COM NEW	893716209
—	FOAMIX PHARMACEUTICALS LTD	200,000	$1.85M	0.2%	$9.25	—	SHS	M46135105
THRM	GENTHERM INC	34,550	$1.745M	0.2%	$42.34	0.0%	COM	37253A103
CLLS	CELLECTIS S A	50,000	$1.729M	0.2%	$34.58	—	SPONSORED ADS	15117K103
—	TOKAI PHARMACEUTICALS INC	146,341	$1.654M	0.2%	$15.14	—	COM	88907J107
—	CONATUS PHARMACEUTICALS INC	220,000	$1.566M	0.2%	$7.12	—	COM	20600T108
—	MANNKIND CORP	3,000	$1.56M	0.2%	—	—	Put	56400P951
—	GENVEC INC	528,325	$1.559M	0.2%	$2.65	—	COM NEW	37246C307
—	OCERA THERAPEUTICS INC	321,254	$1.513M	0.2%	$7.00	—	COM	67552A108
GALT	GALECTIN THERAPEUTICS INC	450,000	$1.508M	0.2%	$3.57	0.0%	COM NEW	363225202
—	GENOCEA BIOSCIENCES INC	124,200	$1.473M	0.2%	$11.86	—	COM	372427104
—	MEDGENICS INC	175,000	$1.411M	0.1%	$5.06	—	COM NEW	58436Q203
—	NEWLINK GENETICS CORP	25,000	$1.368M	0.1%	$39.76	—	COM	651511107
—	ASSEMBLY BIOSCIENCES INC	100,000	$1.324M	0.1%	$13.24	—	COM	045396108
EXEL	EXELIXIS INC	500,000	$1.285M	0.1%	$2.32	0.0%	COM	30161Q104
ASND	ASCENDIS PHARMA A S	70,000	$1.215M	0.1%	$17.36	—	SPONSORED ADR	04351P101
ALDX	ALDEYRA THERAPEUTICS INC	115,000	$1.194M	0.1%	$10.20	0.0%	COM	01438T106
—	STEMLINE THERAPEUTICS INC	80,957	$1.171M	0.1%	$14.46	—	COM	85858C107
—	SAGENT PHARMACEUTICALS INC	50,000	$1.163M	0.1%	$23.26	—	COM	786692103
HRTX	HERON THERAPEUTICS INC	79,900	$1.163M	0.1%	$11.27	0.0%	COM	427746102
—	IMMUNOMEDICS INC	300,000	$1.149M	0.1%	$3.83	—	COM	452907108
—	CYMABAY THERAPEUTICS INC	157,179	$1.088M	0.1%	$6.84	—	COM	23257D103
—	PALATIN TECHNOLOGIES INC	1,040,266	$1.061M	0.1%	$0.93	—	COM PAR $ .01	696077403
—	AURIS MED HLDG AG	186,300	$997K	0.1%	$5.35	—	COM	H03579101
—	JUNO THERAPEUTICS INC	15,000	$910K	0.1%	$52.20	—	COM	48205A109
—	ELEVEN BIOTHERAPEUTICS INC	87,110	$777K	0.1%	$11.88	—	COM	286221106
—	MAST THERAPEUTICS INC	1,374,900	$667K	0.1%	$0.56	—	COM	576314108
—	ACHILLION PHARMACEUTICALS IN	65,538	$646K	0.1%	$12.25	—	COM	00448Q201
—	OHR PHARMACEUTICAL INC	187,500	$476K	0.0%	$2.54	—	COM NEW	67778H200
—	SAPIENS INTL CORP N V	56,420	$463K	0.0%	$8.21	—	SHS NEW	N7716A151
—	BIOLINERX LTD	193,284	$408K	0.0%	$2.11	—	SPONSORED ADR	09071M106
—	SPECTRUM PHARMACEUTICALS INC	50,000	$304K	0.0%	$6.08	—	COM	84763A108
—	ALCOBRA LTD	200	$1,000	0.0%	$3.74	—	SHS	M2239P109
—	LUMENIS LTD	245	$0	0.0%	—	—	SHS CL B	M6778Q121