Siren, L.L.C. Diversified Active

Location: New York, NY

CIK: 0002005245 · Show all filings

Period: Q3 2025 (← Previous) (Next →)

Filing Date: Nov 13, 2025

Total Value: $2.556B (100.0% shares, 0.0% debt)

Holdings (115)

SRRK Scholar Rock Holding Corp 13.5%
Value $344M Shares 9,250,005 Est. Cost $8.78 Unrealized +298.3%
KYMR Kymera Therapeutics Inc 7.6%
Value $194M Shares 3,428,150 Est. Cost $43.02 Unrealized +4.8%
ONC BeOne Medicines AG 6.6%
Value $168M Shares 492,990 Est. Cost $219.52 Unrealized
ARWR Arrowhead Pharmaceuticals Inc 3.6%
Value $92.08M Shares 2,669,880 Est. Cost $23.82 Unrealized -7.7%
BCAX Bicara Therapeutics Inc 3.2%
Value $82.38M Shares 5,216,969 Est. Cost $20.25 Unrealized -44.7%
CNTA Centessa Pharmaceuticals PLC 3.1%
Value $78.27M Shares 3,227,517 Est. Cost $15.58 Unrealized
CRNX Crinetics Pharmaceuticals Inc 2.8%
Value $70.33M Shares 1,688,611 Est. Cost $51.69 Unrealized -38.1%
EWTX Edgewise Therapeutics Inc 2.5%
Value $63.21M Shares 3,897,099 Est. Cost $19.34 Unrealized -26.6%
IRON Disc Medicine Inc 2.4%
Value $60.36M Shares 913,401 Est. Cost $55.39 Unrealized +7.4%
DYN Dyne Therapeutics Inc 2.3%
Value $59.82M Shares 4,729,174 Est. Cost $19.51 Unrealized -41.6%
APLS Apellis Pharmaceuticals Inc 2.3%
Value $58.35M Shares 2,578,396 Est. Cost $35.43 Unrealized -34.2%
RNAM Avidity Biosciences Inc 2.2%
Value $56.01M Shares 1,285,610 Est. Cost $42.99 Unrealized -6.0%
STOK Stoke Therapeutics Inc 2.1%
Value $52.81M Shares 2,247,347 Est. Cost $11.96 Unrealized +43.3%
LXRX Lexicon Pharmaceuticals Inc 2.1%
Value $52.54M Shares 38,918,903 Est. Cost $1.78 Unrealized -36.3%
RYTM Rhythm Pharmaceuticals Inc 2.0%
Value $50.49M Shares 499,975 Est. Cost $63.74 Unrealized +45.6%
TNGX Tango Therapeutics Inc 1.9%
Value $49.42M Shares 5,883,188 Est. Cost $7.39 Unrealized -8.5%
RVMD Revolution Medicines Inc 1.9%
Value $48.74M Shares 1,043,720 Est. Cost $41.26 Unrealized -5.1%
ASND Ascendis Pharma A/S 1.8%
Value $46.89M Shares 235,862 Est. Cost $149.31 Unrealized
RZLT Rezolute Inc 1.8%
Value $45.78M Shares 4,870,000 Est. Cost $6.66 Unrealized 0.0%
SLDB Solid Biosciences Inc 1.8%
Value $45.76M Shares 7,415,905 Est. Cost $5.86 Unrealized -0.3%
SEPN Septerna Inc 1.6%
Value $41.43M Shares 2,202,514 Est. Cost $23.65 Unrealized -44.5%
RCUS Arcus Biosciences Inc 1.5%
Value $39.6M Shares 2,912,077 Est. Cost $13.37 Unrealized -22.2%
TSHA Taysha Gene Therapies Inc 1.4%
Value $36.02M Shares 11,014,737 Est. Cost $2.17 Unrealized +30.7%
TBLA Taboola.com Ltd 1.3%
Value $34M Shares 9,969,495 Est. Cost $3.30 Unrealized +3.9%
XENE Xenon Pharmaceuticals Inc 1.3%
Value $32.63M Shares 812,761 Est. Cost $39.56 Unrealized -11.0%
SLNO Soleno Therapeutics Inc 1.2%
Value $31.59M Shares 467,342 Est. Cost $50.20 Unrealized +47.7%
RAPP Rapport Therapeutics Inc 1.2%
Value $31.29M Shares 1,053,469 Est. Cost $19.15 Unrealized -6.8%
GPCR Structure Therapeutics Inc 1.1%
Value $28.75M Shares 1,026,811 Est. Cost $28.00 Unrealized
WVE WAVE Life Sciences Ltd 1.1%
Value $27.06M Shares 3,696,322 Est. Cost $5.98 Unrealized +35.4%
RELY Remitly Global Inc 1.0%
Value $26.38M Shares 1,618,271 Est. Cost $18.06 Unrealized -0.6%
COGT Cogent Biosciences Inc 1.0%
Value $24.76M Shares 1,724,279 Est. Cost $8.72 Unrealized +35.8%
TRVI Trevi Therapeutics Inc 0.9%
Value $23.21M Shares 2,536,867 Est. Cost $4.03 Unrealized +86.3%
NAMS NewAmsterdam Pharma Company NV 0.9%
Value $21.78M Shares 765,705 Est. Cost $19.51 Unrealized +22.9%
KRRO Korro Bio Inc 0.8%
Value $20.06M Shares 418,833 Est. Cost $42.09 Unrealized -47.3%
ERAS Erasca Inc 0.7%
Value $19.09M Shares 8,757,249 Est. Cost $2.82 Unrealized -43.5%
IHS IHS Holding Limited 0.6%
Value $16.08M Shares 2,357,520 Est. Cost $3.08 Unrealized +117.5%
QURE Uniqure NV 0.6%
Value $16.06M Shares 275,200 Est. Cost $18.16 Unrealized 0.0%
BCYC Bicycle Therapeutics PLC 0.6%
Value $15.58M Shares 2,012,752 Est. Cost $13.30 Unrealized
SLN Silence Therapeutics PLC 0.6%
Value $15.11M Shares 2,911,438 Est. Cost $17.66 Unrealized
RAPT RAPT Therapeutics Inc 0.6%
Value $14.97M Shares 580,466 Est. Cost $13.09 Unrealized 0.0%
UPB Upstream Bio Inc 0.6%
Value $14.83M Shares 788,450 Est. Cost $22.33 Unrealized -30.4%
GOSS Gossamer Bio Inc 0.5%
Value $13.7M Shares 5,208,968 Est. Cost $0.96 Unrealized +129.1%
AVBP Arrivent Biopharma Inc 0.5%
Value $12.91M Shares 700,000 Est. Cost $20.76 Unrealized -5.4%
AMZN Amazon.com Inc 0.5%
Value $12.84M Shares 58,500 Est. Cost $196.43 Unrealized +15.2%
ORIC Oric Pharmaceuticals Inc 0.5%
Value $12.09M Shares 1,007,575 Est. Cost $9.89 Unrealized +6.4%
DNLI Denali Therapeutics Inc 0.5%
Value $11.93M Shares 821,513 Est. Cost $24.79 Unrealized -42.0%
IONQ IONQ Inc 0.4%
Value $10.46M Shares 170,000 Est. Cost $7.62 Unrealized +516.9%
SION Sionna Therapeutics Inc 0.4%
Value $9.558M Shares 325,000 Est. Cost $16.34 Unrealized +33.1%
CRWD CrowdStrike Holdings Inc 0.4%
Value $9.072M Shares 18,500 Est. Cost $287.95 Unrealized +57.9%
MSFT Microsoft Corp 0.3%
Value $8.883M Shares 17,150 Est. Cost $424.79 Unrealized +19.8%
SEER Seer Inc 0.3%
Value $8.68M Shares 4,000,000 Est. Cost $1.75 Unrealized +21.5%
NBIS Nebius Group NV 0.3%
Value $8.151M Shares 72,600 Est. Cost $38.64 Unrealized +79.7%
NMRA Neumora Therapeutics Inc 0.3%
Value $7.932M Shares 4,358,283 Est. Cost $11.80 Unrealized -86.3%
TSM Taiwan Semiconductor Manufacturing Co Ltd 0.3%
Value $7.876M Shares 28,200 Est. Cost $173.74 Unrealized
CRM Salesforce Inc 0.3%
Value $7.134M Shares 30,100 Est. Cost $283.24 Unrealized -11.2%
CGEM Cullinan Therapeutics Inc 0.3%
Value $7.077M Shares 1,193,410 Est. Cost $17.74 Unrealized -58.7%
NVDA NVIDIA Corp 0.3%
Value $6.994M Shares 37,485 Est. Cost $118.94 Unrealized +46.5%
NOW ServiceNow Inc 0.3%
Value $6.558M Shares 7,126 Est. Cost $178.55 Unrealized +4.6%
SYRE Spyre Therapeutics Inc 0.2%
Value $6.178M Shares 368,598 Est. Cost $29.32 Unrealized -44.4%
RNAC Cartesian Therapeutics Inc 0.2%
Value $5.757M Shares 563,272 Est. Cost $15.62 Unrealized -28.1%
PDD PDD Holdings Inc 0.2%
Value $5.736M Shares 43,401 Est. Cost $125.87 Unrealized
ELDN Eledon Pharmaceuticals Inc 0.2%
Value $5.368M Shares 2,072,767 Est. Cost $3.32 Unrealized -12.0%
ADBE Adobe Inc 0.2%
Value $5.309M Shares 15,051 Est. Cost $461.82 Unrealized -22.3%
GOOGL Alphabet Inc 0.2%
Value $5.154M Shares 21,203 Est. Cost $178.77 Unrealized +17.0%
FROG Jfrog Ltd 0.2%
Value $5.07M Shares 107,116 Est. Cost $31.23 Unrealized +44.6%
SGMT Sagimet Biosciences Inc 0.2%
Value $4.972M Shares 724,771 Est. Cost $3.08 Unrealized +163.1%
DT Dynatrace Inc 0.2%
Value $4.856M Shares 100,229 Est. Cost $48.66 Unrealized +4.0%
DDOG Datadog Inc 0.2%
Value $4.689M Shares 32,925 Est. Cost $120.18 Unrealized +14.6%
NBP I-Mab 0.2%
Value $4.407M Shares 1,165,957 Est. Cost $3.78 Unrealized
AGEN Agenus Inc 0.2%
Value $4.097M Shares 1,064,250 Est. Cost $3.19 Unrealized +57.0%
LXEO Lexeo Therapeutics Inc 0.2%
Value $4.007M Shares 603,435 Est. Cost $11.93 Unrealized -59.4%
BDTX Black Diamond Therapeutics Inc 0.2%
Value $3.966M Shares 1,046,517 Est. Cost $5.44 Unrealized -46.2%
WHWK Whitehawk Therapeutics Inc 0.2%
Value $3.956M Shares 2,082,000 Est. Cost $2.61 Unrealized -29.6%
VTVT vTv Therapeutics Inc 0.1%
Value $3.806M Shares 163,000 Est. Cost $17.30 Unrealized 0.0%
TIL Instil Bio Inc 0.1%
Value $3.642M Shares 203,933 Est. Cost $23.39 Unrealized +8.5%
FHTX Foghorn Therapeutics Inc 0.1%
Value $3.524M Shares 720,720 Est. Cost $7.24 Unrealized -26.8%
PRQR ProQR Therapeutics NV 0.1%
Value $3.306M Shares 1,552,183 Est. Cost $3.18 Unrealized -31.2%
EDU New Oriental Education & Technology Group Inc 0.1%
Value $3.29M Shares 62,000 Est. Cost $67.56 Unrealized
CRWV CoreWeave Inc 0.1%
Value $3.284M Shares 24,000 Est. Cost $118.31 Unrealized 0.0%
PEPG PepGen Inc 0.1%
Value $3.234M Shares 700,000 Est. Cost $1.61 Unrealized 0.0%
GTLB GitLab Inc 0.1%
Value $2.885M Shares 64,000 Est. Cost $45.74 Unrealized +0.0%
BEKE Ke Holdings Inc 0.1%
Value $2.755M Shares 145,000 Est. Cost $19.71 Unrealized
PANW Palo Alto Networks Inc 0.1%
Value $2.739M Shares 13,450 Est. Cost $180.75 Unrealized +5.9%
TENX Tenax Therapeutics Inc 0.1%
Value $2.682M Shares 352,441 Est. Cost $6.11 Unrealized 0.0%
WK Workiva Inc 0.1%
Value $2.582M Shares 30,000 Est. Cost $83.42 Unrealized -9.9%
QCOM Qualcomm Inc 0.1%
Value $2.329M Shares 14,000 Est. Cost $171.16 Unrealized -8.2%
BIOA BIOAGE Labs Inc 0.1%
Value $2.249M Shares 382,406 Est. Cost $19.40 Unrealized -75.9%
KDP Keurig Dr Pepper Inc 0.1%
Value $1.966M Shares 77,050 Est. Cost $30.82 Unrealized 0.0%
HUBS HubSpot Inc 0.1%
Value $1.871M Shares 4,000 Est. Cost $565.03 Unrealized -11.0%
CMG Chipotle Mexican Grill Inc 0.1%
Value $1.862M Shares 47,500 Est. Cost $45.03 Unrealized 0.0%
KLRS Kalaris Therapeutics Inc 0.1%
Value $1.84M Shares 318,264 Est. Cost $9.06 Unrealized -63.5%
Generation Bio Co 0.1%
Value $1.817M Shares 296,892 Est. Cost $6.12 Unrealized
CLBT Cellebrite DI Ltd 0.1%
Value $1.668M Shares 90,000 Est. Cost $17.12 Unrealized -8.2%
PRMB Primo Brands Corp 0.1%
Value $1.657M Shares 75,000 Est. Cost $28.92 Unrealized -10.5%
SPOT Spotify Technology SA 0.1%
Value $1.517M Shares 2,173 Est. Cost $699.24 Unrealized 0.0%
NIQ NIQ Global Intelligence PLC 0.1%
Value $1.492M Shares 95,000 Est. Cost $17.40 Unrealized 0.0%
MNDY monday.com Ltd 0.1%
Value $1.356M Shares 7,000 Est. Cost $230.24 Unrealized 0.0%
SAIL SailPoint Inc 0.0%
Value $1.104M Shares 50,000 Est. Cost $21.79 Unrealized -3.9%
ESTC Elastic NV 0.0%
Value $1.056M Shares 12,500 Est. Cost $84.19 Unrealized 0.0%
IREN IREN Ltd 0.0%
Value $938K Shares 20,000 Est. Cost $24.29 Unrealized 0.0%
SEMR SEMrush Holdings Inc 0.0%
Value $885K Shares 125,000 Est. Cost $13.58 Unrealized -40.0%
AS Amer Sports Inc 0.0%
Value $869K Shares 25,000 Est. Cost $37.71 Unrealized 0.0%
PINS Pinterest Inc 0.0%
Value $804K Shares 25,000 Est. Cost $36.26 Unrealized 0.0%
FIG Figma Inc 0.0%
Value $778K Shares 15,000 Est. Cost $68.66 Unrealized 0.0%
CFLT Confluent Inc 0.0%
Value $743K Shares 37,500 Est. Cost $20.91 Unrealized 0.0%
PCOR Procore Technologies Inc 0.0%
Value $729K Shares 10,000 Est. Cost $61.37 Unrealized +13.8%
ALAB Astera Labs Inc 0.0%
Value $685K Shares 3,500 Est. Cost $164.44 Unrealized 0.0%
TSLA Tesla Inc 0.0%
Value $667K Shares 1,500 Est. Cost $333.26 Unrealized +4.1%
CHYM Chime Financial Inc 0.0%
Value $504K Shares 25,000 Est. Cost $28.41 Unrealized 0.0%
CCC CCC Intelligent Solutions Holdings Inc 0.0%
Value $456K Shares 50,000 Est. Cost $8.94 Unrealized +8.1%
KVUE Kenvue Inc 0.0%
Value $406K Shares 25,000 Est. Cost $20.06 Unrealized 0.0%
VRT Vertiv Holdings Co 0.0%
Value $302K Shares 2,000 Est. Cost $97.15 Unrealized +37.2%
CYCN Cyclerion Therapeutics Inc 0.0%
Value $267K Shares 116,155 Est. Cost $2.94 Unrealized -7.5%
CRBU Caribou Biosciences Inc 0.0%
Value $245K Shares 105,347 Est. Cost $2.05 Unrealized -7.8%
IRWD Ironwood Pharmaceuticals Inc 0.0%
Value $145K Shares 110,532 Est. Cost $5.38 Unrealized -80.7%