ORASURE TECHNOLOGIES INC

Institution	Shares	Value ($000)
Archon Capital Management LLC	573,503	$1,388
Intrinsic Edge Capital Management LLC	349,064	$845
Numerai GP LLC	41,370	$100
Jump Financial, LLC	54,093	$131
Jain Global LLC	31,440	$76
Brevan Howard Capital Management LP	26,496	$64
HighTower Advisors, LLC	20,142	$49
Quadrature Capital Ltd	11,475	$28
Global Retirement Partners, LLC	4,103	$10
BROWN BROTHERS HARRIMAN & CO	295	$1

Increased Positions (32)

Peapod Lane Capital LLC

Value ($000) $2,465 (+13.9%) Shares 1,018,470 (+51.1%)

Murphy Pohlad Asset Management LLC

Value ($000) $278 (-1.1%) Shares 114,867 (+31.2%)

XTX Topco Ltd

Value ($000) $293 (+19.0%) Shares 121,144 (+57.8%)

KLP KAPITALFORVALTNING AS

Value ($000) $879 (+49.0%) Shares 363,300 (+97.7%)

Qube Research & Technologies Ltd

Value ($000) $525 (+239.0%) Shares 216,941 (+349.7%)

SEI INVESTMENTS CO

Value ($000) $446 (+330.7%) Shares 184,226 (+471.3%)

MORGAN STANLEY

Value ($000) $1,281 (+23.3%) Shares 529,262 (+63.5%)

JANE STREET GROUP, LLC

Value ($000) $865 (+65.6%) Shares 357,496 (+119.6%)

CITADEL ADVISORS LLC

Value ($000) $953 (+9.1%) Shares 393,693 (+44.8%)

WELLS FARGO & COMPANY/MN

Value ($000) $2,122 (-16.6%) Shares 877,030 (+10.6%)

HSBC HOLDINGS PLC

Value ($000) $325 (+48.9%) Shares 135,091 (+96.3%)

BANK OF AMERICA CORP /DE/

Value ($000) $320 (-6.1%) Shares 132,429 (+24.5%)

Graham Capital Management, L.P.

Value ($000) $61 (+70.5%) Shares 25,339 (+126.1%)

Invesco Ltd.

Value ($000) $390 (-16.3%) Shares 161,182 (+11.1%)

BARCLAYS PLC

Value ($000) $505 (-39.6%) Shares 208,625 (+6.6%)

GSA CAPITAL PARTNERS LLP

Value ($000) $0 (+4.0%) Shares 151,086 (+37.6%)

Russell Investments Group, Ltd.

Value ($000) $106 (-14.5%) Shares 43,636 (+13.3%)

BNP PARIBAS ARBITRAGE, SA

Value ($000) $48 (-2.9%) Shares 19,676 (+28.8%)

SUSQUEHANNA INTERNATIONAL GROUP, LLP

Value ($000) $71 (-14.5%) Shares 29,215 (+13.4%)

Rockefeller Capital Management L.P.

Value ($000) $8 (+491.1%) Shares 3,473 (+684.0%)

Institution	Prev Shares	Curr Shares	Change
Peapod Lane Capital LLC	674,033	1,018,470	+344,437 (+51.1%)
Murphy Pohlad Asset Management LLC	87,567	114,867	+27,300 (+31.2%)
XTX Topco Ltd	76,765	121,144	+44,379 (+57.8%)
KLP KAPITALFORVALTNING AS	183,800	363,300	+179,500 (+97.7%)
Qube Research & Technologies Ltd	48,242	216,941	+168,699 (+349.7%)
SEI INVESTMENTS CO	32,244	184,226	+151,982 (+471.3%)
MORGAN STANLEY	323,658	529,262	+205,604 (+63.5%)
JANE STREET GROUP, LLC	162,781	357,496	+194,715 (+119.6%)
CITADEL ADVISORS LLC	271,965	393,693	+121,728 (+44.8%)
WELLS FARGO & COMPANY/MN	793,172	877,030	+83,858 (+10.6%)
HSBC HOLDINGS PLC	68,831	135,091	+66,260 (+96.3%)
BANK OF AMERICA CORP /DE/	106,346	132,429	+26,083 (+24.5%)
Graham Capital Management, L.P.	11,206	25,339	+14,133 (+126.1%)
Invesco Ltd.	145,141	161,182	+16,041 (+11.1%)
BARCLAYS PLC	195,793	208,625	+12,832 (+6.6%)
GSA CAPITAL PARTNERS LLP	109,790	151,086	+41,296 (+37.6%)
Russell Investments Group, Ltd.	38,498	43,636	+5,138 (+13.3%)
BNP PARIBAS ARBITRAGE, SA	15,275	19,676	+4,401 (+28.8%)
SUSQUEHANNA INTERNATIONAL GROUP, LLP	25,753	29,215	+3,462 (+13.4%)
Rockefeller Capital Management L.P.	443	3,473	+3,030 (+684.0%)

Decreased Positions (51)

Steamboat Capital Partners, LLC

Value ($000) $968 (-77.7%) Shares 400,000 (-70.4%)

CANNELL CAPITAL LLC

Value ($000) $4,729 (-29.8%) Shares 1,954,012 (-6.9%)

GAGNON SECURITIES LLC

Value ($000) $3,799 (-25.8%) Shares 1,569,782 (-1.6%)

Significant Wealth Partners LLC

Value ($000) $47 (-63.8%) Shares 19,397 (-52.0%)

BRIDGEWAY CAPITAL MANAGEMENT, LLC

Value ($000) $1,058 (-41.4%) Shares 437,263 (-22.2%)

SYSTEMATIC FINANCIAL MANAGEMENT LP

Value ($000) $5,996 (-26.0%) Shares 2,477,574 (-1.8%)

MILLENNIUM MANAGEMENT LLC

Value ($000) $2,087 (-69.2%) Shares 862,397 (-59.2%)

JPMORGAN CHASE & CO

Value ($000) $961 (-80.9%) Shares 397,085 (-74.7%)

DIMENSIONAL FUND ADVISORS LP

Value ($000) $7,886 (-32.4%) Shares 3,258,593 (-10.4%)

ROYAL BANK OF CANADA

Value ($000) $15 (-98.7%) Shares 6,017 (-98.3%)

NEUBERGER BERMAN GROUP LLC

Value ($000) $9,652 (-28.4%) Shares 3,984,854 (-5.2%)

Quadrant Private Wealth Management, LLC

Value ($000) $49 (-49.5%) Shares 20,260 (-33.0%)

BlackRock, Inc.

Value ($000) $15,602 (-27.6%) Shares 6,447,181 (-3.9%)

RENAISSANCE TECHNOLOGIES LLC

Value ($000) $5,191 (-28.5%) Shares 2,145,003 (-5.1%)

Empowered Funds, LLC

Value ($000) $120 (-62.4%) Shares 49,631 (-50.2%)

GOLDMAN SACHS GROUP INC

Value ($000) $767 (-50.0%) Shares 317,066 (-33.7%)

GEODE CAPITAL MANAGEMENT, LLC

Value ($000) $4,239 (-29.4%) Shares 1,751,383 (-6.3%)

Bank of New York Mellon Corp

Value ($000) $515 (-46.3%) Shares 212,862 (-28.7%)

TUDOR INVESTMENT CORP ET AL

Value ($000) $452 (-44.1%) Shares 186,901 (-25.8%)

JACOBS LEVY EQUITY MANAGEMENT, INC

Value ($000) $2,393 (-28.1%) Shares 988,698 (-4.6%)

Institution	Prev Shares	Curr Shares	Change
Steamboat Capital Partners, LLC	1,351,581	400,000	-951,581 (-70.4%)
CANNELL CAPITAL LLC	2,099,815	1,954,012	-145,803 (-6.9%)
GAGNON SECURITIES LLC	1,594,771	1,569,782	-24,989 (-1.6%)
Significant Wealth Partners LLC	40,391	19,397	-20,994 (-52.0%)
BRIDGEWAY CAPITAL MANAGEMENT, LLC	562,263	437,263	-125,000 (-22.2%)
SYSTEMATIC FINANCIAL MANAGEMENT LP	2,522,444	2,477,574	-44,870 (-1.8%)
MILLENNIUM MANAGEMENT LLC	2,112,507	862,397	-1,250,110 (-59.2%)
JPMORGAN CHASE & CO	1,571,228	397,085	-1,174,143 (-74.7%)
DIMENSIONAL FUND ADVISORS LP	3,636,260	3,258,593	-377,667 (-10.4%)
ROYAL BANK OF CANADA	356,665	6,017	-350,648 (-98.3%)
NEUBERGER BERMAN GROUP LLC	4,203,838	3,984,854	-218,984 (-5.2%)
Quadrant Private Wealth Management, LLC	30,260	20,260	-10,000 (-33.0%)
BlackRock, Inc.	6,708,884	6,447,181	-261,703 (-3.9%)
RENAISSANCE TECHNOLOGIES LLC	2,261,103	2,145,003	-116,100 (-5.1%)
Empowered Funds, LLC	99,631	49,631	-50,000 (-50.2%)
GOLDMAN SACHS GROUP INC	478,449	317,066	-161,383 (-33.7%)
GEODE CAPITAL MANAGEMENT, LLC	1,869,711	1,751,383	-118,328 (-6.3%)
Bank of New York Mellon Corp	298,596	212,862	-85,734 (-28.7%)
TUDOR INVESTMENT CORP ET AL	251,867	186,901	-64,966 (-25.8%)
JACOBS LEVY EQUITY MANAGEMENT, INC	1,036,797	988,698	-48,099 (-4.6%)

Exited Positions (20)

Factorial Partners, LLC

Value ($000) $897 Shares 279,592

Brooklyn Investment Group

Value ($000) $141 Shares 46,831

RBF Capital, LLC

Value ($000) $154 Shares 48,096

Allianz Asset Management GmbH

Value ($000) $1,843 Shares 574,266

TWO SIGMA INVESTMENTS, LP

Value ($000) $139 Shares 43,300

ENVESTNET ASSET MANAGEMENT INC

Value ($000) $89 Shares 27,695

COLDSTREAM CAPITAL MANAGEMENT INC

Value ($000) $51 Shares 16,018

Private Advisor Group, LLC

Value ($000) $57 Shares 17,905

STATE OF WISCONSIN INVESTMENT BOARD

Value ($000) $58 Shares 18,142

Engineers Gate Manager LP

Value ($000) $37 Shares 11,481

Pathstone Holdings, LLC

Value ($000) $34 Shares 10,437

PRUDENTIAL FINANCIAL INC

Value ($000) $33 Shares 10,339

Fortitude Family Office, LLC

Value ($000) $3 Shares 873

GROUP ONE TRADING, L.P.

Value ($000) $3 Shares 852

JONES FINANCIAL COMPANIES LLLP

Value ($000) $1 Shares 400

NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO

Value ($000) $1 Shares 383

Advisory Services Network, LLC

Value ($000) $1 Shares 200

HRT FINANCIAL LP

Value ($000) $0 Shares 69,326

SALEM INVESTMENT COUNSELORS INC

Value ($000) $0 Shares 85

Covestor Ltd

Value ($000) $0 Shares 92

Institution	Prev Shares	Prev Value ($000)
Factorial Partners, LLC	279,592	$897
Brooklyn Investment Group	46,831	$141
RBF Capital, LLC	48,096	$154
Allianz Asset Management GmbH	574,266	$1,843
TWO SIGMA INVESTMENTS, LP	43,300	$139
ENVESTNET ASSET MANAGEMENT INC	27,695	$89
COLDSTREAM CAPITAL MANAGEMENT INC	16,018	$51
Private Advisor Group, LLC	17,905	$57
STATE OF WISCONSIN INVESTMENT BOARD	18,142	$58
Engineers Gate Manager LP	11,481	$37
Pathstone Holdings, LLC	10,437	$34
PRUDENTIAL FINANCIAL INC	10,339	$33
Fortitude Family Office, LLC	873	$3
GROUP ONE TRADING, L.P.	852	$3
JONES FINANCIAL COMPANIES LLLP	400	$1
NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO	383	$1
Advisory Services Network, LLC	200	$1
HRT FINANCIAL LP	69,326	$0
SALEM INVESTMENT COUNSELORS INC	85	$0
Covestor Ltd	92	$0